Abstract: Photon starvation causes streaks and noise and seriously impairs the diagnostic value of the CT imaging. To reduce streaks and noise, a new scheme of adaptive Gaussian filtering relies on the diffusion-derived scale-space concept in one embodiment of the current invention. In scale-space view, filtering by Gaussians of different sizes is similar to decompose the data into a sequence of scales. As the scale measure, the variance of the filter linearly relates to the noise standard deviation of a predetermined noise model in the new filtering method. The new filter has only one optional parameter that remains stable once tuned. Although single-pass processing using the new filter generally achieves desired results, iterations are optionally performed.

Abstract: More than two acquired energy or spectral M bins are used for photon counting detectors in a CT system. In the pre-reconstruction data decomposition, the measured photo counts in the M acquired spectral bines are combined into a predetermined fewer number of processed or weighted spectral bines N, which is at least two in number and represents a number of selected basic materials. Since the N basis materials are selected in the imaged subject where N<M, the noise is balanced in the pre-reconstruction data decomposition. In some more detail, after the photon counts n(E) is acquired in each of the M spectral bins as indicated by E=1 to M at each of the detector units for every view, the M acquired spectral bins is combined into the N processed spectral bins so that the photon counts in the N processed spectral bins are substantially balanced to have a least number of differences among the N processed spectral bins.

Abstract: An apparatus and method for reducing the X-ray flux in a computed-tomography (CT) scanner that includes a rotating X-ray source and a plurality of stationary photon-counting detectors configured to capture incident X-ray photons emitted from the X-ray source. A bowtie filter equipped with an edge filter that can be positioned in a reconfigurable manner such that the high X-ray flux at the leading edge of an X-ray fan beam incident on the detector is reduced. The CT apparatus includes a processor that is configured to compute the displacement of the edge filter in either a static or dynamic manner such that that the intensity of X-ray flux at the detectors in within acceptable operating limits.

Abstract: An apparatus and method for dynamically calibrating a computed-tomography (CT) scanner that includes a rotating X-ray source and a plurality of stationary energy-discriminating detectors configured to capture incident X-ray photons emitted from the X-ray source. A bowtie filter with a unique geometry and material composition is used to generate reference beams of a desired intensity. The apparatus includes a processor that is configured to remove a scattering background based on data obtained from the reference beams and compute a change in a predetermined calibration function.

Abstract: More than two acquired energy or spectral M bins are used for photon counting detectors in a CT system. In the pre-reconstruction data decomposition, the measured photo counts in the M acquired spectral bines are combined into a predetermined fewer number of processed or weighted spectral bines N, which is at least two in number and represents a number of selected basic materials. Since the N basis materials are selected in the imaged subject where N<M, the noise is balanced in the pre-reconstruction data decomposition. In some more detail, after the photon counts n(E) is acquired in each of the M spectral bins as indicated by E=1 to M at each of the detector units for every view, the M acquired spectral bins is combined into the N processed spectral bins so that the photon counts in the N processed spectral bins are substantially balanced to have a least number of differences among the N processed spectral bins.

Abstract: A detector includes a photon-counting detector (PCD) layer and a cathode layer arranged adjacent to the PCD layer. The detector further includes a plurality of pixilated anodes arranged adjacent to the photon-counting detecting layer on a side opposite to the cathode layer. The detector also includes a plurality of collimator segments arranged above the cathode layer so as to block a portion of X-ray photons emitted from an X-ray source from reaching the anodes, where each collimator segment is arranged above a portion of at least one anode.

Abstract: An apparatus and method for dynamically calibrating a computed-tomography (CT) scanner that includes a rotating X-ray source and a plurality of stationary energy-discriminating detectors configured to capture incident X-ray photons emitted from the X-ray source. A bowtie filter with a unique geometry and material composition is used to generate reference beams of a desired intensity. The apparatus includes a processor that is configured to remove a scattering background based on data obtained from the reference beams and compute a change in a predetermined calibration function.

Abstract: Provided are techniques for processing a multidimensional query. For each multidimensional expression in the multidimensional query, the multidimensional expression is evaluated to generate a representation that includes an evaluation context, a degeneration status, and condensed value storage that does not store data that would be replicated due to degeneration, and the representation is stored.

Abstract: A method and apparatus for determining a parameter vector that includes a plurality of parameters of a detector pileup model of a photon-counting detector, the detector pileup model being used for pileup correction for a spectral computed-tomography scanner. The method includes setting values of the parameters, the parameters including a dead time parameter and individual probabilities of different pileup events, the probabilities including a probability of single photon events, a probability of double quasi-coincident photon events, and a probability of at least three quasi-coincident photon events. The method include determining, using (1) a detector response model, (2) an incident spectrum, and (3) the set values of the parameter vector, a plurality of component spectra, each component spectrum corresponding to one of the individual probabilities of the different pileup events, and summing the plurality of component spectra to generate an output spectrum.

Abstract: A medical imaging system can include a frame that has a bore that has a central longitudinal axis that intersects a target area for imaging, and a radiation source to emit radiation in radial directions towards the target area to form a fan or cone of emitted radiation that irradiates a cross-section of the target area with respect to the longitudinal axis. The system can include one or more detector arrays including a plurality of detector segments that extend along a detector axis that extends in a direction that is effectively parallel to the longitudinal axis, such that radiation emitted from the radiation source passes through the target area and is incident on one or more of the detector segments. The detector segments can each include a detecting surface that is tilted such that the detecting surface has a tilt (e.g., a non-zero slope) with respect to the detector axis.

Abstract: An apparatus and method for controlling movement of a plurality of fixed detectors arranged in a computed tomography (CT) system that includes a rotating X-ray source. The method including obtaining a view angle of the X-ray source, determining a tilt angle for a detector of the plurality of detectors that is within a scan field-of-view of the X-ray source at the obtained view angle so that an outer face of the detector directly faces the X-ray source, and causing the detector to be moved to the determined tilt angle.

Abstract: A spectral computed tomography scanner apparatus, including a rotating X-ray source, a plurality of fixed energy-discriminating detectors, a processor that generates a shadow map that indicates, for each detector/view angle, a shadow state of the detector, the shadow state indicating that one of X-rays are completely blocked by a second detector and do not reach the detector, the X-rays are partially blocked by the second detector and partially reach the detector, the X-rays are not blocked by any of the detectors and reach the detector, and the detector is not with the scan field of view at the view angle, and a controller configured to cause the scanner apparatus to perform a scan of an object over a first range of view angles to collect view data, wherein the processor is configured to perform scatter correction using the collected view data and the generated shadow map.

Abstract: A method for detector angular response calibration in computed-tomography (CT) comprising capturing incident X-ray photons, emitted from an X-ray source, via a plurality of energy-discriminating detectors, determining photon counts of the captured incident X-ray photons in a plurality of energy windows at each energy-discriminating detector, and adjusting the photon counts based on a pre-determined detector angular response calibration look-up table for a given view for each energy-discriminating detector at each energy window.

Abstract: A method for photon count-loss calibration in a computed-tomography (CT) scanner, including capturing incident X-ray photons via a plurality of energy-discriminating detectors, determining photon counts of the captured incident X-ray photons in a plurality of energy windows at each energy-discriminating detector, and adjusting the determined photon counts in each energy window for each energy-discriminating detector based on a pre-determined photon count-loss look-up table and the determined photon counts.

Abstract: A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.

Abstract: The current invention is generally related to a data acquisition and or image processing method and system for acquiring and or processing sparse channel data. The sparse channel is implemented in a data acquisition system having a predetermined wider pitch between the adjacent detector cells than that in the currently available imaging systems at least in one predetermined direction. In one implementation, the sparse channel data is acquired by the sparse channel data acquisition system, and an image is reconstructed from the sparse channel data according to a predetermined chord based reconstruction method eliminating the differentiation along the channel direction and utilizing a pair of proper weights.

Abstract: Provided are techniques for processing a multidimensional query. For each multidimensional expression in the multidimensional query, the multidimensional expression is evaluated to generate a representation that includes an evaluation context, a degeneration status, and condensed value storage that does not store data that would be replicated due to degeneration, and the representation is stored.

Abstract: A computed-tomography apparatus that includes a CT scanner including an X-ray source and a detector covering respective angle ranges in the axial and transaxial planes of the CT scanner. The CT detector includes first detector elements disposed on a first surface to capture incident X-ray photons emitted from the X-ray source, and second detector elements sparsely disposed on a second surface different from the first surface, the second surface being farther away from the scanner than the first surface, the second detector elements being smaller in number than the first detector elements. Each of the second detector elements is reachable only by X-ray photons originating in a small angle range around a line connecting the X-ray source and a center of the surface of the detector element, the small angle range being determined by the predetermined distance separating the first and second surfaces and a size of the detector element.

Abstract: According to one embodiment of the present invention, a level of a first hierarchy and a second hierarchy of data attributes is determined where the first hierarchy and the second hierarchy share the determined level and each subordinate hierarchical level. The embodiment further removes from a set of tuples of a database operation at least one tuple that lacks corresponding data in a data source based on the tuple containing elements corresponding to non-intersecting sets of attributes at the determined level. Embodiments of the present invention include a method, system and computer program product for reducing tuple sets in substantially the same manner described above.

Abstract: The application is related to compositions and methods for the treatment of hypersensitivity, wherein the compositions comprise a particle packaged with immunostimulatory nucleic acids. The compositions of the invention are particularly useful in the treatment of atopic eczema, asthma and IgE-mediated allergy (type I allergy), especially pollen allergy and house dust allergy.