Abstract: Described is a multi-path handwriting recognition framework based upon stroke segmentation, symbol recognition, two-dimensional structure analysis and semantic structure analysis. Electronic pen input corresponding to handwritten input (e.g., a chemical expression) is recognized and output via a data structure, which may include multiple recognition candidates. A recognition framework performs stroke segmentation and symbol recognition on the input, and analyzes the structure of the input to output the data structure corresponding to recognition results. For chemical expressions, the structural analysis may perform a conditional sub-expression analysis for inorganic expressions, or organic bond detection, connection relationship analysis, organic atom determination and/or conditional sub-expression analysis for organic expressions. The structural analysis also performs subscript, superscript analysis and character determination. Further analysis may be performed, e.g.

Abstract: The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen of the invention, wherein said antigen of the invention is CCR5 of the invention, gastrin of the invention, CXCR4 of the invention, CETP of the invention or C5a of the invention. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of diseases in which the antigen of the invention mediates, or contributes to the condition, particularly for the treatment of AIDS, gastrointestinal cancers, coronary heart diseases or inflammatory diseases. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.

Abstract: A method of obtaining a computed tomography image of an object includes determining linear terms and non-linear beam hardening terms in a pair of line integral equations for dual-energy projection data from inserting average and difference from average attenuation terms, obtaining an initial solution of the line integral equation by setting the non-linear beam hardening terms to zero, and iteratively solving the line integral equations to obtain one line integral equations for each basis material. Attenuation by the first basis material corresponds to a photoelectric attenuation process, and attenuation by the second basis material corresponds to a Compton attenuation process. The line integral equations can be inverted by an inverse Radon procedure such as filtered backprojection to give images of each basis material. The images of each basis material can then be optionally combined to give monochromatic images, density and effective atomic number images, or photoelectric and Compton processes images.

Abstract: Ink-parser-parameter optimization may be performed via parallel processing to accelerate searching for a set of optimal ink-parser parameters. Evaluators may parse pages of ink notes with different groups of parameters and may compute corresponding values for evaluation functions. Separate evaluation functions may be defined for the following types of ink-parker parsing engines: writing parser, writing/drawing classification, table detection, and list detection. A searcher may perform a grid-searching algorithm or a genetic algorithm to generate groups of parameters and may then pass the parameters to available evaluators for evaluation until evaluation-function values for a group of parameters satisfy a convergence condition.

Abstract: A computed tomography apparatus and method using line data estimated from circle data and scanogram data. An image of a subject is reconstructed using the circle data and the estimated line data. The circle data and scanogram data may be weighted in estimating the line data. The apparatus and method are useful in diminishing or eliminating streak artifacts in reconstructed images such as images including the spine.

Abstract: A mechanism for recognizing and inputting handwritten mathematical expressions into a computer by providing part of a multi-path framework is described. The part of the multi-path framework includes a subscript/superscript analysis and character determination component that is designed to identify subscript and superscript elements. A method for analyzing a handwritten mathematical expression includes receiving a symbols corresponding to handwritten mathematical expression input strokes, identifying subscript and/or superscript structures, and determining a character for each symbol of the set. A graph of vertexes and edges may be created based upon the set of symbols and the graph may be searched to determine optimized candidates.

Abstract: A mechanism for recognizing and inputting handwritten mathematical expressions into a computer by providing a part of a multi-path framework is described. The part of the multi-path framework includes a symbol grouping and recognition component that is designed to group input strokes that correspond to a handwritten mathematical expression into a symbol and to recognize the symbol based upon information associated with the grouped input strokes. A method for grouping and recognizing symbols of a handwritten mathematical expression includes receiving a plurality of input strokes corresponding to a handwritten mathematical expression, grouping the plurality of input strokes into symbols, recognizing the symbols based upon information, such as shape and time series information, associated with the grouped input strokes. Intra-group and inter-group information associated with the plurality of input strokes may be utilized to group the input strokes.

Abstract: A mechanism for recognizing and inputting handwritten mathematical expressions into a computer by providing a multi-path framework is described. The framework may include symbol grouping and recognition, tabular structure analysis, subordinate sub-expression analysis, subscript/superscript analysis and character determination, and semantic structure analysis components. A method for recognizing a handwritten mathematical expression includes receiving a plurality of input strokes corresponding to a handwritten mathematical expression and providing a candidate list of recognized candidate expressions based upon the input strokes. Input strokes are grouped into symbols, tabular structures are determined, dominant symbol candidates and subordinate symbols are determined, and subscript and superscript structures are determined.

Abstract: A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.

Abstract: The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen array, wherein the antigen is an IL-15 protein, an IL-15 mutein or an IL-15 fragment. More specifically, the invention provides a composition comprising a virus-like particle, and at least one IL-15 protein, IL-15 mutein or at least one IL-15 fragment linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of inflammatory and chronic autoimmune diseases. The composition of the invention efficiently induces immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Abstract: A multi-language interfaces system includes a storage unit, a processing unit, and a language switch unit; the storage unit stores an executable code containing a variable code and multiple language packs; the processing unit is electrically connected for transmission to the storage unit to execute the executable codes; and the language switch unit is respectively electrically connected for transmission to the storage unit and the processing unit to provide a signal to the processing unit where the variable code is converted into one of those language packs.

Abstract: A computer case includes a chassis (70), a cage (10) pivotably engaging with the chassis, a securing member (50) and an intermediate member (30). The cage has a locked position and a unlocked position. The securing member is mounted to the chassis. A receiving portion (57) is formed at the securing member. The intermediate member pivotably connects with the securing member and the cage respectively, and includes a resilient portion (35) corresponding to the receiving portion. When the cage is in the locked position, the resilient portion engages in the receiving portion. When the cage is in the unlocked position, the resilient portion disengages from the receiving portion.

Abstract: Described is a technology by which online recognition of handwritten input data is combined with offline recognition and processing to obtain a combined recognition result. In general, the combination improves overall recognition accuracy. In one aspect, online and offline recognition is separately performed to obtain online and offline character-level recognition scores for candidates (hypotheses). A statistical analysis-based combination algorithm, an AdaBoost algorithm, and/or a neural network-based combination may determine a combination function to combine the scores to produce a result set of one or more results. Online and offline radical-level recognition may be performed. For example, a HMM recognizer may generate online radical scores used to build a radical graph, which is then rescored using the offline radical recognition scores. Paths in the rescored graph are then searched to provide the combined recognition result, e.g., corresponding to the path with the highest score.

Abstract: An exemplary method for online character recognition of East Asian characters includes acquiring time sequential, online ink data for a handwritten East Asian character, conditioning the ink data to produce conditioned ink data where the conditioned ink data includes information as to writing sequence of the handwritten East Asian character and extracting features from the conditioned ink data where the features include a tangent feature, a curvature feature, a local length feature, a connection point feature and an imaginary stroke feature. Such a method may determine neighborhoods for ink data and extract features for each neighborhood. An exemplary Hidden Markov Model based character recognition system may use various exemplary methods for training and character recognition.

Abstract: A method and system for compressing and displaying a digital ink trace. Raw ink data is smoothed, and sharp points of the smoothed line are found. Curve-fitting is then used to generate a mathematical expression that defines the line segments between adjacent sharp points. The ink trace then is represented by a backbone spline that includes the sharp points and the mathematical expressions for the line segments. Thickness information, such as pressure or acceleration information, is combined with the backbone spline to provide a compressed ink file that represents a contour curve of the original ink trace. A display module uses an algorithm to separate the contour curve into a sequence of straight lines. A set of pixels is then generated for the display of each straight line using a novel antialiasing method. The pixels at the ends of adjacent straight lines are aligned using a weighting algorithm.

Abstract: A method and apparatus for reconstruction of a region of interest (ROI) for an object using an imaging system is provided. The imaging system may substantially exactly reconstruct the ROI with a straight line trajectory. In the straight line trajectory, the ROI is not bounded or encircled by the actual trajectory of the source (e.g., no chords that are composed from two points on the source trajectory intersect or fill the ROI to be imaged). However, the ROI may be substantially reconstructed by using “virtual” chords to reconstruct the ROI. The virtual chords are such that no point on the trajectory is included in the virtual chord (such as one that is parallel to the straight line trajectory). These virtual chords may intersect and fill the ROI, thus enabling substantially exact reconstruction. Further, in reconstructing the image, the straight line trajectory may be assumed to be infinite in length.

Abstract: Exemplary methods, systems, and computer-readable media for developing, training and/or using models for online handwriting recognition of characters are described. An exemplary method for building a trainable radical-based HMM for use in character recognition includes defining radical nodes, where a radical node represents a structural element of an character, and defining connection nodes, where a connection node represents a spatial relationship between two or more radicals. Such a method may include determining a number of paths in the radical-based HMM using subsequence direction histogram vector (SDHV) clustering and determining a number of states in the radical-based HMM using curvature scale space-based (CSS) corner detection.

Abstract: Exemplary techniques are described for selecting radical sets for use in probabilistic East Asian character recognition algorithms. An exemplary technique includes applying a decomposition rule to each East Asian character of the set to generate a progressive splitting graph where the progressive splitting graph comprises radicals as nodes, formulating an optimization problem to find an optimal set of radicals to represent the set of East Asian characters using maximum likelihood and minimum description length and solving the optimization problem for the optimal set of radicals. Another exemplary technique includes selecting an optimal set of radicals by using a general function that characterizes a radical with respect to other East Asian characters and a complex function that characterizes complexity of a radical.

Abstract: Electronic ink layout analysis systems and methods provide flexibility and efficiency in organizing, analyzing, and processing digital ink. These layout analysis systems and methods allow users substantial freedom in entering electronic ink into a pen-based computer system. Using these systems and methods, a user's input digital ink is not constrained by requirements that a user write in a specific screen orientation, that a user write in one specific orientation on all portions of a page, or that a user write using a specific minimum or maximum sized stroke. Rather, the systems and methods freely allow the user to write anywhere on a given page, in any orientation or size, while still enabling effective and efficient handwriting recognition and other processing of the input digital ink.

Abstract: A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.