Abstract: A component manufacturing method includes a step in which a robot for attachment gripping a long frame presses the frame against a tabular skin and a step in which, in a state in which the frame is pressed against the skin, a robot for riveting gripping a first rivet inserts the first rivet into a first through-hole formed in the skin and a second through-hole formed in the frame. In the step, the robot for riveting changes a position in the gripped first rivet in a direction perpendicular to an axial direction of the first rivet according to a force received by the first rivet from the skin or the frame.

Abstract: A display device according to the present invention comprises: a light source configured to emit light in a manner capable of changing an emission direction as needed within a predetermined irradiation region; a first screen located in said irradiation region; a first reflective unit disposed closer to said light source than said first screen; a second reflective unit disposed at a position where the light reflected by said first reflective unit reaches; and a second screen disposed at a position where the light reflected by said second reflective unit reaches.

Abstract: The present invention relates to a labeling technique which can facilitate the metabolism in the liver after administration to patients without the reduction in the antibody function, thereby reducing accumulation of radionuclides in an organ such as the liver, and provides a modified antibody containing an IgG antibody and an IgG-binding peptide bound to the IgG antibody. The IgG-binding peptide has an amino acid sequence consisting of 13 to 17 amino acid residues, such as GPDCAYH(Xaa1)GELVWCTFH wherein Xaa1 represents a lysine residue, a cysteine residue, an aspartic acid residue, a glutamic acid residue, 2-aminosuberic acid, or diaminopropionic acid, and a compound represented by the following formula (II-1) is linked at a position of the lysine residue via a modification linker to the N terminus of the IgG-binding peptide.

Abstract: The invention relates to an antibody which binds to cell adhesion molecule 3 (CADM3) or an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment thereof, a nucleic acid comprising a nucleotide sequence encoding the antibody or the antibody fragment thereof, a transformant cell comprising a vector comprising the nucleic acid, a method for producing the antibody or the antibody fragment thereof, a composition comprising the antibody or the antibody fragment thereof, and a method for detecting or measuring an antigen present in the brain, a method for diagnosing or treating a brain disease, a method for enhancing the property of accumulating in a brain of an antibody, and a method for increasing the amount of an antibody in the brain, each of which using the antibody or the antibody fragment thereof, and the like.

Abstract: It is an object of the present invention to provide a method for modifying an antibody in a specific and simple manner, and others. The present invention relates to: an IgG-binding peptide, an IgG-binding peptide modified with a crosslinking agent, a complex of an IgG-binding peptide modified with the crosslinking agent and IgG, a method for producing the complex, and others.

Abstract: The present invention provides a compound represented by formula [I] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme.

Abstract: To facilitate mounting of a second member on a first member having a plate shape while the first member is supported in a state of being deformable due to gravity. A method for manufacturing a component includes: a step (S13) where a supporting robot supports a skin having a plate shape in a state where the skin is deformable due to gravity, and a support state of the skin is changed based on teaching data based on a deformed shape of the skin, which is recorded in advance in a storage unit and which is obtained at the time of mounting a frame on the skin; and a step (S15) where a mounting robot makes the frame overlap with the skin where a support state is changed.

Abstract: A drive apparatus is provided for driving a multi-phase rotating electric machine. The rotating electric machine includes a plurality of winding groups for respective phases. The drive apparatus includes a first inverter connected with start terminals of the winding groups of the rotating electric machine, a second inverter connected with intermediate terminals of the winding groups, and an energization controller configured to selectively perform energization of the winding groups by the first inverter and energization of the winding groups by the second inverter. Each of the first and second inverters includes a plurality of switch pairs respectively corresponding to the winding groups and each consisting of an upper-arm switch and a lower-arm switch that are connected in series with each other. Moreover, each of the upper-arm and lower-arm switches of the first inverter is configured to have bidirectionally-conducting and bidirectionally-blocking functions.

Abstract: A sleeve is provided inside a body configuring a channel selector valve, and first and second guide portions with which outer peripheries of first and second land portions of a valve body are in sliding contact are formed on one end side and the other end side of the sleeve. The first and second guide portions are formed to axially overlap with the first and second land portions so as to abut the first and second land portions at all times when the valve body axially moves. The valve body includes a plurality of communicating paths penetrating through the valve body in the axial direction, and, in the sleeve, a first space formed on one end side of the valve body and a second space formed on the other end side of the valve body communicate with each other via the communicating paths.

Abstract: The present invention relates to a carrier core material for electrophotographic developer, having a ferrite composition and having a supernatant transmittance of 85.0% or more, a method for producing the carrier core material, a carrier for electrophotographic developer, containing the carrier core material, and a developer containing the carrier.

Abstract: The present invention provides a technique enabling modification of a soluble protein and in particular regioselective modification of a soluble protein. More specifically, the present invention provides a compound having an affinity substance to a soluble protein, a cleavable portion, and a reactive group represented by the following Formula (I): A-L-B-R??(I) wherein A is an affinity substance to a soluble protein; L is a cleavable linker which is a divalent group comprising a cleavable portion; B is (a) a divalent group comprising a bioorthogonal functional group or (b) a divalent group comprising no bioorthogonal functional group; and R is a reactive group to the soluble protein; or a salt thereof.

Abstract: The present invention relates to an IgG-binding peptide comprising a ligand capable of binding to a radioactive metal nuclide, an IgG-binding peptide labeled with a radioactive metal nuclide, a conjugate of the IgG-binding peptide and IgG, and a radionuclide imaging agent or a diagnostic agent for cancer comprising the IgG-binding peptide or the conjugate, etc.

Abstract: When a hybrid vehicle slides down during a predetermined drive of the hybrid vehicle with disconnection of a first motor and a second motor from a power storage device by a relay, the hybrid vehicle controls the second motor, such that a torque in a direction according to a shift position is output from the second motor by regenerative drive of the second motor and controls the first motor, such that electric power generated by regenerative drive of the second motor is consumed by driving the first motor.

Abstract: The cooling system is provided with an internal passage for circulating the cooling water inside an internal combustion engine, a water pump provided in an one end side external passage connected to the one end portion of the internal passage, and an ECU configured to execute a water flow switching control that switches a cooling water flow in the internal passage between a forward flow directed from the one end portion of the internal passage to the other end portion and a reverse flow directed from the other end portion to the one end portion.

Abstract: A display device according to the present invention comprises: a light source configured to emit light in a manner capable of changing an emission direction as needed within a predetermined irradiation region; a first screen located in said irradiation region; a first reflective unit disposed closer to said light source than said first screen; a second reflective unit disposed at a position where the light reflected by said first reflective unit reaches; and a second screen disposed at a position where the light reflected by said second reflective unit reaches.

Abstract: A transport jig includes: a frame member; and a support section that is installed on the frame member and that supports a plurality of elongated members. The elongated members are each entirely housed inside the frame member in a lengthwise direction and the support section supports the plurality of elongated members in parallel with one another in one direction.

Abstract: The present invention provides an IgG-binding peptide which can be used for the purification of IgG and has excellent stability, e.g., alkali stability. The present invention also provides a method for purifying IgG using the IgG-binding peptide. Specifically, the present invention relates to a solid-phase support including an IgG-binding peptide, an IgG separation column including the solid-phase support, a kit including the solid-phase support or the column, and a method for purifying IgG using the solid-phase support or the column.

Abstract: The invention relates to an antibody which binds to myelin oligodendrocyte glycoprotein (MOG), an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment, a nucleic acid containing a nucleotide sequence which encodes the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment, a composition containing the antibody or the antibody fragment and a method for detecting or measuring an antigen that is present in the brain, a method for diagnosing or treating a brain disease, a method for improving the property of an antibody of accumulating in the brain and a method for increasing the amount of an antibody in the brain which use the antibody or the antibody fragment.

Abstract: To facilitate mounting of a second member on a first member having a plate shape while the first member is supported in a state of being deformable due to gravity. A method for manufacturing a component includes: a step (S13) where a supporting robot supports a skin having a plate shape in a state where the skin is deformable due to gravity, and a support state of the skin is changed based on teaching data based on a deformed shape of the skin, which is recorded in advance in a storage unit and which is obtained at the time of mounting a frame on the skin; and a step (S15) where a mounting robot makes the frame overlap with the skin where a support state is changed.

Abstract: A component production method includes: a step of binding a long frame by a plurality of support devices arranged along the frame; a step of measuring, with a distance sensor, a distance to the frame supported by the plurality of support devices; a step in which, based on frame shape data prerecorded in a memory, the support devices move support positions where the frame is supported so that a calculated radial position of the frame being supported by the support devices matches the data about the frame shape; a step of fixing the frame in a state in which the data about the frame shape matches the radial position of the frame; and a step of performing a hole-making operation on the fixed frame.