Abstract: The present invention discloses a user personalized operating method and operating apparatus for use in a Chemistry analyzer, said method comprises following steps: initiating the operating software of the Chemistry analyzer; loading a profile, said profile comprising at least a database containing combinations of controls for respective users; retrieving configuration information of the function components from the database; and setting display interface and function components by the Chemistry analyzer according to the configuration information. The present invention realizes different combinations of controls and display interface by use of the profile and thus operating software of different versions can be provided.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: A method and apparatus for performing arithmetic encoding/decoding in an arithmetic encoder is disclosed. It comprises: firstly, when performing binary arithmetic encoding/decoding in the arithmetic encoder, an interval update process for arithmetic encoding/decoding to be performed in the original domain is mapped to the logarithm domain, and the interval update computation is implemented with direct add/subtract operations; during arithmetic encoding/decoding in the logarithm domain, data conversions between the original domain and the logarithm domain are performed by approximations; and after encoding/decoding a symbol, its probability is updated when necessary, the update being performed with add/subtract operations in the logarithm domain. It can be seen that with the arithmetic encoding/decoding solutions of the disclosure, the arithmetic encoding/decoding process and the probability estimation involved therein are mapped to the logarithm domain.

Abstract: A binary coding and decoding method and apparatus for MVD (Motion Vector Difference) absolute values, includes: dividing symbols for MVD absolute values to be coded into a plurality of subsets according to probability distribution properties; assigning a binary codeword for each subset; assigning a binary codeword for each symbol in each subset; concatenating and outputting the binary codeword for each subset and the binary codeword for each symbol in the subset, as the binary coding result. At the decoding side, decoding operations are performed by using a principle corresponding to that at the coding side. In this manner, the invention makes full use of the source properties on one hand, and effectively prevents the codeword length from being too long on the other hand. It has been experimentally testified that a better compression effect may be achieved during arithmetic coding process and thus the image coding performance may be improved effectively.

Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TPO activity, particularly diseases or disorders that involve thrombocytopenia.

Abstract: The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit, PDGFR?, PDGFR?, CSF1R, Abl, BCR-Abl, CSK, JNK1, JNK2, p38, p70S6K, TGF?, SRC, EGFR, trkB, FGFR3, FLT3, Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2?, BRK, KDR, c-raf or b-raf kinase, or mutant forms thereof.

Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.

Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S. More particularly, the present invention provides compounds having Formula I: wherein Q is morpholinyl; and A, R5, R6, R7, R8, R9 and Ar are substituents.

Abstract: This invention is directed to novel bicyclic compounds, to the uses of these compounds in various medicinal applications, including treating disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections, and to pharmaceutical compositions comprising these compounds.

Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the FAK, Abl, BCR-Abl, PDGF-R, c-Kit, NPM-ALK, Flt-3, JAK2 and c-Met kinases.

Abstract: The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particularly diseases associated with EDG receptor mediated signal transduction.

Abstract: This invention is directed to novel bicyclic compounds, to the uses of these compounds in various medicinal applications, including treating disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections, and to pharmaceutical compositions comprising these compounds.

Abstract: The present invention is directed to novel benzimidazoles according to representative structures I and II, and their derivatives that possess antibacterial activity. This invention is also directed to compositions including the benzimidazole derivatives, and methods for using the same.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: Epothilone A, epothilone B, analogs of epothilone and libraries of epothilone analogs are synthesized. Epothilone A and B are known anticancers agents that derive their anticancer activity by the prevention of mitosis through the induction and stabilization of microtubulin assembly. The analogs of epothilone are novel. Several of the analogs are demonstrated to have a superior cytotoxic activity as compared to epothilone A or epothilone B as demonstrated by their enhanced ability to induce the polymerization and stabilization of microtubules.

Abstract: The invention relates to a video encoding and decoding technical field of the signal processing, especially relates to a method for video clip assisted by clip identifier. The method defines a clip identifier on the video encoding and decoding rule as an identifier used specially for video stream clip. If the encoded video bit stream is clipped, then said clip identifier is inserted to the bit stream or used to replace the original identifier which functions as a start flag. The clip of the video bit stream can be operated conveniently by the invention. The features of the invention are: the bits, which mark whether the clipped video bit stream may be decoded and displayed incorrectly or not, are not required to appear in the unclipped bit stream; if it clips at a certain point of the bit stream, then said identifier will appear at this point to indicate that a problem in which the picture can not be decoded normally due to the predictive reference data being clipped may appear.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: This invention is directed to novel bicyclic compounds, to the uses of these compounds in various medicinal applications, including treating disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections, and to pharmaceutical compositions comprising these compounds.

Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.