Abstract: The invention provides an easy-to-remove water gradient contact lens. Such a water gradient contact lens comprises imperfections (ditches and/or gaps) in the anterior outer hydrogel layer and can be made according to a cost-effective method involving a step of partially or completely shielding reactive functional groups in selected zones on the anterior surface a to-be-coated contact lens before grafting a layer of a non-silicone hydrogel material. With the imperfections in the anterior outer hydrogel layer, the surface lubricity of the anterior surface is inferior to that of the posterior surface. By adjusting the shape, size, density, and rotational distribution of the imperfections, one also can selectively adjust and optimize the surface lubricity of the anterior surface of a water gradient contact lens so as to have improved lens handlability while maintaining other desirable properties.

Abstract: The present application discloses a display device brightness compensation look-up table obtaining method. The method includes a parameter reading step, an initial grayscale brightness detection step, a compensation region brightness detection step, a compensation data obtaining step, and a compensation look-up table generation step. The above method solves a technical issue that conventional demura technologies cannot uniform brightness of the display panel to result in poor quality of the display panel.

Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

Abstract: A backlight driving method is provided. The method includes: determining a first duration of a first active pulse phase in a backlight driving signal corresponding to a target frame of a to-be displayed picture in a display panel, based on a target duty ratio and a first period corresponding to a target previous frame; wherein the target previous frame is a frame preceding the target frame, and the backlight driving signal is configured to drive a backlight of the display panel; and determining a second duration based on a maximum period corresponding to a frame at a lowest refresh frequency of the display panel and the first period, to delay a start time of the first active pulse phase based on the second duration.

Abstract: Methods and apparatuses are disclosed for data communication between terminal device and application server. According to an embodiment, a network exposure node receives, from a first application server in operator trust domain, configuration information that can be used for data delivery for a terminal device. The network exposure node receives data from one of the terminal device and the first application server and forwards the data to the other of the terminal device and the first application server based on the configuration information.

Abstract: TA preparation method for off-the-shelf human umbilical cord-derived mesenchymal stem cells includes culturing an isolated umbilical cord tissue blocks to obtain P0 cells; carrying out passage on the P0 cells twice to obtain P2 cells, and cryopreserving the P2 cells; the cryopreserved P2 cells are subjected to thawing and passage twice to obtain P4 cells, and the P4 cells are cryopreserved; the cryopreserved P4 cells are subjected to thawing and passage once to obtain P5 cells, and the P5 cells are sequentially digested, washed and resuspended to obtain the human umbilical cord-derived mesenchymal stem cells. The present invention also adopts cryopreservation method to develop a cryopreservation preparation of human umbilical cord-derived mesenchymal stem cells. The cryopreservation preparation is convenient for storage and can be directly administered intravenously after thawing without changing the liquid, avoiding possible contamination risk during dispensing, and is more conducive to clinical use.

Abstract: A cup lid that facilitates convenient operation by allowing effort saving opening of a water passing hole by using only one hand, wherein the cup lid has a main lid and an auxiliary lid; an upper surface of the main lid has the water passing hole and an air vent; the auxiliary lid is rotatably mounted on the upper surface of the main lid, and being axially limited with respect to the main lid. Rotation of the auxiliary lid will cause a water passing port disposed thereon to open or close the water passing hole; the auxiliary lid also has an air guide slot in which the air vent can slide therein when the auxiliary lid rotates, and the air guide slot is in communication with an external environment. A container using the cup lid is also provided.

Abstract: The present disclosure relates to a continuous integration automated test system and method, an electronic device, and a storage medium. The system includes: a deploying server, configured to, in response to detecting one or more events each indicating deploying project codes to a tested server, for each of the one or more events, acquire a test script of a project to which the project codes belong, and send the test script to a testing server, then send a control instruction for executing the test script to the testing server; the testing server, configured to receive the test script through a designated port and store the test script in a corresponding project folder, and in response to receiving the control instruction, execute the test script to output a test instruction to the tested server; the tested server, configured to, in response to receiving the test instruction, test codes before the project codes, and output running data to the testing server.

Abstract: The present invention relates to a crystalline form and/or maleate, phosphate, L-tartrate, and adipate of the compound represented by the structural formula I, and various crystalline forms of various salt forms, and preparation methods and applications thereof.

Abstract: The present application provides a chain-type roller coating apparatus, including a liquid coating roller and a synchronizing wheel. The synchronizing wheel is provided with a mounting hole. A proximity switch is arranged on an outer side of the synchronizing wheel. The synchronizing wheel is further provided with a trigger element which is configured to be sensed by the proximity switch. The liquid coating roller is assembled with the mounting hole of the synchronizing wheel by a connecting shaft. A shaft main body of the connecting shaft is equipped with a rotation support device configured to support a rotation of the shaft main body. The rotation support device is equipped with a first lifting driving device configured to drive the rotation support device to ascend or descend vertically. A ranging sensor is arranged exactly above the liquid coating roller.

Abstract: The present invention discloses the method and system for predicting adverse drug-drug interactions by recovering the multi-attribute information of drugs and the medium. The method includes: collecting adverse drug-drug interactions data and multi-attribute data of drugs; constructing the recovery model of multi-attribute absent feature of drugs; correcting the recovery model of multi-attribute absent feature of drugs by the cosine similarity regularization term, and solving the corrected recovery model to obtain the common features and unique features of multi-attribute information of drugs; obtaining the multi-attribute information of two drugs, calculating common features and unique features of their multi-attribute information as the inputs of the prediction model to predict their adverse drug-drug interactions.

Abstract: This application disclose a method for constructing an indoor map. The method includes: obtaining a plurality of first tracks and a second track, where each first track is a flat-layer track located on an indoor horizontal layer, the second track is a cross-layer track located between different indoor horizontal layers, and a first wireless signal information similarity between each first track point of the first track and each second track point is less than a first threshold; and performing layering on the plurality of first tracks based on a second wireless signal information similarity between the plurality of first tracks, to obtain a layering result, where the layering result may be used to construct an indoor map.

Abstract: The disclosure discloses an ultrasonic-assisted pretreatment method for extraction of multiple steroid hormones in a sediment, including the following steps: (1) lyophilizing the sediment, grinding the sediment, and passing the ground sediment through a 40-60-mesh sieve; (2) placing the sample obtained in step (1) in a container; (3) adding an extractant to the container in step (2), shaking the mixture for 15 s-30 s, centrifuging the mixture to collect an supernatant after ultrasonication, and repeating extraction three times; where the extractants used in the three times of extraction are two of methanol, acetonitrile and acetone; and (4) after mixing the supernatants of the three times of extraction obtained in step (3), concentrating the mixture under a nitrogen flow at 20-30° C., passing the concentrated mixture through a filter, and performing detection. By using the method of the disclosure, the maximum recovery can be up to 100%.

Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including a vinylic monomer having a primary amino or thiolactone group to form an unprocessed contact lens having the polymer matrix of which have pendant primary amino or thiolactone groups, a step of one-pot multistep reactions based on thiolactone chemistry (aminolysis and thiol-induced graft polymerization of a photochromic vinylic monomer to the polymer matrix) which are carried out only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.

Abstract: Methods and systems provide for dynamic prediction of agenda item coverage in a communication session. In one embodiment, the system connects to a communication session with a plurality of participants; receives one or more agenda items and a number of utterances; classifies each agenda item as a long item or a short item; for agenda items classified as long items, extracts one or more topics from the utterances, and uses a topic detection model to predict whether a topic related to each agenda item classified as a long item has been covered; for agenda items classified as short items, applies one or more matching methods to predict whether one or more of the utterances within the sentence threshold cover each agenda item classified as a short item; and transmits, to one or more client devices, a status of the agenda items for the communication session.

Abstract: Methods and apparatuses for communication between lightweight machine to machine (LwM2M) client and server are disclosed. According to an embodiment, a network exposure node performs configuration such that the network exposure node can transfer traffic between a LwM2M client and at least one LwM2M server over non-Internet protocol data delivery (NIDD) through reliable data service (RDS) protocol. The network exposure node transfers traffic between the LwM2M client and the at least one LwM2M server based on the configuration.

Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including mutant EGFR and mutant HER2 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including mutant EGFR and mutant HER2 activity, are described herein.

Abstract: Disclosed are a cocaine esterase mutant and use thereof. The cocaine esterase mutant is obtained by mutating a wildtype cocaine esterase, an amino acid sequence of the wildtype cocaine esterase is shown as SEQ ID No.1, the cocaine esterase mutant is T172R/G173Q/L196C/I301C, or additionally added with V116K point mutation, or additionally added with A51 site mutation, and the A51 site mutation is L, Y, V, F or W. Catalytic efficiency of the cocaine esterase mutant screened on a cocaine toxic metabolite benzoylecgonine is greatly improved compared with that of a wildtype enzyme.

Abstract: The disclosure discloses a preparation method and product of carbon fiber reinforced polymer composites with a designable characteristic structure. The method includes: (a) choosing carbon fabrics as raw material, where a predetermined number of the fabrics are selected to deposit the reinforcement phase; (b) coating all carbon fabrics with resin matrix, placing the fabrics layer by layer, where the carbon fabrics with the reinforcement phases are placed in a predetermined layer, meanwhile a micro power supply is placed in a setting layer during the stacking process, then a prefabricated product is obtained; (c) placing the prefabricated product in a vacuum bag then evacuating and sealing, hot pressing the sealed prefabricated product, finally the carbon fiber reinforced polymer composite product in the vacuum bag after hot pressing is successfully manufactured.