Abstract: Processes for chemically treating polyaromatic feedstock to form aromatic-containing oligomers or polymers are provided. The processes are characterized by treatment of a plurality of different polyaromatic hydrocarbon molecules and/or polyheterocyclic molecules present in polyaromatic feedstock with a first reagent so as to functionalize the molecules. Further treatment in a second step affords oligomeric or polymeric products which may be crosslinked. The products may be thermoplastic or thermoset materials and may find use in, for example, infrastructure applications, composites, fillers, fire retardants and 3-D printing materials.

Abstract: The present disclosure is directed to tetrahydroquinazoline derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV naïve cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

Abstract: A bogie and a rail vehicle, wherein the bogie includes: a framework, a wheel pair connected to the framework, a braking hanger fixed to the framework, a hanger slider used for fixedly connecting to a vehicle wheel braking clamp, and a transmission member; the hanger slider is connected to the braking hanger, and the transmission member is connected to the hanger slider; a first end of the transmission member extends to a side surface of a vehicle wheel in the wheel pair, and the transmission member is used to drive the hanger slider to move along the lateral direction with respect to the braking hanger when the first end is subjected to a thrust applied in the lateral direction by the vehicle wheel, so that the vehicle wheel braking clamp moves to a position corresponding to the vehicle wheel.

Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: Compounds and methods are described herein that are useful in brachytherapy. A compound of the present invention may comprise: a cancer cell targeting agent (e.g., transferrin); a protecting group; a cross-linking moiety; and an enzyme (e.g., a protein, ribozyme, abzyme, or abiological catalyst). Compounds and methods of the present invention may be used for localizing a radioactive compound and/or for creating a self-amplifying response.

Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

Abstract: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: Methods for determining nitrogen and/or sulfur containing surfactant residual concentrations in oil and/or water phases of an oil and water system, particularly produced oil and water from an oil or gas well, are provided. The methods utilize pyro-chemiluminescence/pyro-fluorescence techniques which quantify the total residual surfactants in both oil and water phases. The methods may be applied broadly in areas where quantifying or monitoring surfactant concentrations in solution is required.

Abstract: A head worn equipment and visual feedback method and device thereof. The head worn equipment includes: a support frame, an image acquiring component, a display component, and a processor. The image acquiring component and the display component are disposed on the support frame. When the head worn equipment is in use, the display component is within a visual perception range of a user. The image acquiring component is configured to acquire a captured image. The processor acquires the captured image acquired by the image acquiring component, determines an indication color for display on the basis of the captured image, and controls the display component to display the indication color, so as to indicate a viewing direction of the image acquiring component for the user.

Abstract: A virtual or augmented reality headset that enables use while leaning backwards against a head support or lying down. The front goggles of the headset are relatively small and comfortable compared to typical bulky, heavy headsets that restrict head movement. The goggles are connected to a headband that is constructed from a soft, compliant material to function as a pillow when leaning the head back against a support. The size and weight of the headset may be further reduced by moving the batteries or other components to a separate module that may be for example worn around the neck. The goggles or headband may also contain speakers that direct sound to the ears via integrated directional sound paths while leaving the ears uncovered. The goggles may have an automated mechanism to adjust the distance between left and right lenses to match a user's intraocular distance.

Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

Abstract: The methods and apparatuses (including systems and device) described herein may be used to accurately and comfortably monitor and track body temperature using a wearable device that can be positioned inside a patient's ear for measuring the patient's temperature, sleeping quality, or other vital signs. These systems and methods may also include a base station and a remote analytics unit (e.g., software, hardware or firmware, including application software that may run on a hand-held or wearable electronics device). The inter-aural device (earplug device) may record and pre-process information that may then be adaptively passed on the remote analytics unit for further processing. The earplug device may engage the remote analytics unit with to download and process the temperature measurement data from the device, to electrically charge the device and also to communicate wirelessly with a smart phone or different types of mobile devices.

Abstract: A method involves implantably detecting changes in posture of a patient's body. Baroreflex responses to the posture changes are determined. An autonomic tone of the patient is determined based on the baroreflex responses. Based on the autonomic tone, various patient susceptibilities to disease may be determined, including susceptibilities to heart disease, arrhythmia, and/or sudden cardiac death.

Abstract: A head worn equipment and visual feedback method and device thereof. The head worn equipment includes: a support frame, an image acquiring component, a display component, and a processor. The image acquiring component and the display component are disposed on the support frame. When the head worn equipment is in use, the display component is within a visual perception range of a user. The image acquiring component is configured to acquire a captured image. The processor acquires the captured image acquired by the image acquiring component, determines an indication color for display on the basis of the captured image, and controls the display component to display the indication color, so as to indicate a viewing direction of the image acquiring component for the user.

Abstract: The present invention relates to compounds of the formulas (IA) and (IB) and pharmaceutically acceptable salts thereof, wherein A and R1-R6, are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.