Abstract: A pyridine derivative and use thereof are provided. The compound has an obvious inhibitory effect on the activity of KRAS and PI3K proteins, can be used as a KRAS and/or PI3K protein inhibitor, and can be used for preparing a drug for treatment of diseases such as KRAS or PI3K protein-mediated cancer. The compound has an extremely strong inhibitory effect on a KRAS G12C inhibitor (e.g. AMG-510) drug-resistant cancer cells, and has a wide application prospect thereof.

Abstract: An oscillating tool includes a housing; a motor in the housing; a first blade clamp; a blade clamp shaft; and a second blade clamp on the blade clamp shaft. The blade clamp shaft includes a latching portion to engage a seat. The oscillating tool also includes a blade clamp spring configured to bias the latching portion into engagement with the seat.

Abstract: There is disclosed a transmitting node for a Radio Access Network, the transmitting node being adapted for transmitting, based on one or more transmission parameters, of reference signaling, and/or signaling including reference signaling, wherein the reference signaling may comprise phase tracking reference signaling and wherein the one or more transmission parameters comprise a Modulation and Coding Scheme (MCS).

Abstract: A phase shifter and a preparation method thereof, and an electronic device. The phase shifter includes: an adjustable dielectric layer, arranged between a first electrode layer and a second electrode layer, and including a first support structure, wherein the first support structure is arranged on at least one side of a first region, and an orthographic projection of the first support structure on a first base plate is at least non-overlapping with an orthographic projection of the first region on the first base plate. The phase shifter provided in the present application is arranged in the non-capacitive overlap region between the first base plate and the second base plate through the first support structure, which can not only provide good support, but also reduce or even eliminate the impact on phase shifting, achieving large phase shift amount, high uniformity of phase shift degrees, and low loss.

Abstract: An optical imaging lens from an object side to an image side includes a first lens element to a sixth lens element. The first lens element has negative refracting power, a periphery region of the object-side surface of the first lens element is convex, the second lens element has positive refracting power, an optical-axis region of the image-side surface of the second lens element is convex, an optical-axis region of the object-side surface of the third lens element is convex, an optical-axis region of the image-side surface of the third lens element is convex. Only the above-mentioned six lens elements have refracting power. AAGF is a distance from the object-side surface of the first lens element to the object-side surface of the second lens element along the optical axis and T6 is a thickness of the sixth lens element along the optical axis to satisfy AAGF/T6?2.000.

Abstract: A heating element includes: a porous substrate; a heat dissipation layer disposed on the porous substrate, the heat dissipation layer having a porous structure; and a heating layer disposed on a surface of the heat dissipation layer away from the porous substrate. In an embodiment, a thickness of the heat dissipation layer is less than a thickness of the heating layer, and/or a porosity of the heat dissipation layer is greater than a porosity of the heating layer, and/or the heat dissipation layer and the heating layer each have a strip-shaped structure, and a line width of the heat dissipation layer is greater than a line width of the heating layer.

Abstract: The invention relates to a field of polymer preparation and discloses a method for promoting phase-separation of polymer solution. The phase-separation method of polymer solution of the invention comprises: at least a portion of the polymer solution is subjected to a heat treatment under flowing so that the polymer solution is divided into a clear liquid phase and a concentrated liquid phase, wherein the Reynolds number of the polymer solution flowing is 0.2-30. By performing the heat treatment under specific Reynolds number conditions, the invention permits to reduce the temperature of phase-separation of solution, reduce the time of phase-separation of solution, and significantly reduce the material consumption and energy consumption of the entire process, compared with the existing technology that only performs phase-separation through heat treatment.

Abstract: The present disclosure provides a video encoding method, a decoding method, and an apparatus. The video encoding method includes: obtaining an original reference video frame and an original target video frame to be encoded; adjusting a resolution of the original target video frame to obtain an adjusted target video frame with a first preset resolution; and performing feature extraction on the adjusted target video frame to obtain a target feature through a feature extraction network corresponding to the first preset resolution; encoding the original reference video frame and the target features respectively to obtain a video bitstream, and performing video frame reconstruction based on the video bitstream to generate a reconstructed video frame with a same resolution as the original target video frame.

Abstract: Provided are a corrosion-resistant oxide dispersion strengthened steel and a method for preparing the corrosion-resistant oxide dispersion strengthened steel. The corrosion-resistant oxide dispersion strengthened steel includes in percentage by mass: Cr at 8.0 wt %-10.0 wt %, Al at 4.0 wt %-6.0 wt %, Ce at 0.2 wt %-0.8 wt %, Y at 0.2 wt %-0.4 wt %, O at 0.05 wt %-0.3 wt %, C less than or equal to 0.0016 wt %, and the balance of Fe.

Abstract: The compositions and methods described herein are directed to treating solid tumors using CAR T therapy. For example, the compositions include CAR T cells comprising an extracellular domain that binds OR2I1P, LY6G6D, LRRC15, LY6K, GCC, GFRA4, F2RL2, QRFPR, IQGAP3, SIGLEC15, HAVCR1, PSG9, KISS1R, PRAME, HCN4, DPEP3, TMEM270, HER2, SLC7A3, SPRR2F, SLC45A2, CHRM1, CHRNA2, STEAP1B, FCRL2, Luteinizing hormone receptor, EDB, or CLDN18.2.

Abstract: The present invention discloses an intelligent ward round method and system based on an SSVEP electroencephalogram signal, the method including: the interactive terminal is used to present a visual stimulus source that includes a plurality of candidate intention options to the patient, the acquisition terminal is used to collect the patient's electroencephalogram signal, the electroencephalogram signal obtained by the acquisition terminal is transmitted to the interactive terminal for electroencephalogram signal recognition, the patient's expression intention is determined, and the expression intentions comprise disease intentions, privacy intentions, psychological intentions, physiological intentions, environmental intentions, and safety intentions, and the intelligent ward round is completed. This method greatly improving the ability of communication between the patient and medical staff.

Abstract: The present invention discloses a dyskinesia rehabilitation training method and system based on electroencephalogram signal recognition; the method includes: the convolutional neural network is used to recognize the electroencephalogram signal, analyze the patient's motor intention, convert the motor intention into a control instruction for the exoskeleton device, drive the patient's limb movement by controlling the movement of the exoskeleton device, and assist the patient to complete the movement disorder rehabilitation training. In this method, the self-attention mechanism and self-distillation training were used to establish an electroencephalogram signal recognition model, analyzing the patient's motor intention to help motor nerve remodeling, which broke the passive and single problem of traditional rehabilitation methods, realized active rehabilitation of patients, and significantly improved the rehabilitation efficacy.

Abstract: A solar cell is provided, including a substrate having a first surface and a second surface, a first dielectric layer formed on the first surface, a first doped polysilicon layer formed on the first dielectric layer, a second dielectric layer formed on the second surface, a second doped polysilicon layer formed on the second dielectric layer, a first passivation layer formed on the first doped polysilicon layer, a second passivation layer formed on the second doped polysilicon layer, first electrodes and second electrodes. The first doped polysilicon layer is doped with an N-type doping element and has a surface having a first roughness, the second doped polysilicon layer is doped with a P-type doping element and has a surface having a second roughness, and the second roughness is less than the first roughness.

Abstract: The present disclosure provides an ion trap apparatus and a saddle point moving method for the ion trap apparatus. The ion trap apparatus comprises: an insulating base material, the insulating base material being a concave structure; and at least two segments of arc-shaped metal reflective electrodes, wherein the arc-shaped metal reflective electrodes cover the front side of the insulating base material, the front side being a concave surface; each segment of the arc-shaped metal reflective electrodes is electrically insulated; and each segment of the arc-shaped metal reflective electrodes is used to receive a radio frequency voltage which has the same frequency, the same phase and an adjustable amplitude. The apparatus may achieve ideal imaging while improving the light collection efficiency, thereby improving the success rate of the preparation of ion-photon entangled states.

Abstract: Provided are a corrosion-resistant oxide dispersion strengthened steel and a method for preparing the corrosion-resistant oxide dispersion strengthened steel. The corrosion-resistant oxide dispersion strengthened steel includes in percentage by mass: Cr at 8.0 wt %-10.0 wt %, Al at 4.0 wt %-6.0 wt %, Ce at 0.2 wt %-0.8 wt %, Y at 0.2 wt %-0.4 wt %, O at 0.05 wt %-0.3 wt %, C less than or equal to 0.0016 wt %, and the balance of Fe.

Abstract: A method including deforming the reference sample frame through generator in an initial generative model to generate reconstructed sample frames; inputting each reconstructed sample frame and the corresponding to-be-encoded sample frame into a first discriminator in the initial generative model to obtain a first identification result; splicing the to-be-encoded sample frames in timestamp order to obtain a spliced to-be-encoded sample frame, and splicing the reconstructed sample frames to obtain a spliced reconstructed sample frame; inputting the spliced to-be-encoded sample frame and the spliced reconstructed sample frame into a second discriminator in the initial generative model to obtain a second identification result; obtaining an adversarial loss value based on the first identification result and the second identification result; and training the initial generative model based on the adversarial loss value.

Abstract: A magnetoresistive random access memory (MRAM) includes a pillar structure having a bottom electrode and a magnetic tunnel junction (MTJ) having a reference layer, a free layer and a tunnel barrier disposed between the reference layer and the free layer. The MTJ is disposed on the bottom electrode. A top electrode is disposed on the MTJ. The top electrode includes two or more tiers wherein each tier successively includes a smaller footprint.

Abstract: Embodiments described herein relate to an optical device and methods of forming an optical device. The optical device includes a substrate, an illumination source, a capping layer, an encapsulation layer, and a passivation layer. The encapsulation layer includes a first atomic layer deposition (ALD) layer, a chemical vapor deposition (CVD) layer, and a second ALD layer. The method includes disposing a capping layer over an illumination layer, the illumination layer disposed over a substrate in a processing chamber; disposing a first atomic layer deposition (ALD) layer over the capping layer; disposing a chemical vapor deposition (CVD) layer over the first ALD layer; disposing a second ALD layer over the CVD layer; and disposing a passivation layer over the second ALD layer.

Abstract: A display panel and a display device are provided. An organic light-emitting layer includes a doped region and an undoped region, and the undoped region is located between the doped region and the hole blocking layer. When the display panel is in a low grayscale display state, an exciton concentration distribution curve of the organic light-emitting layer includes a first peak located in the doped region and a second peak located in the undoped region, and a peak value of the second peak is less than a peak value of the first peak.

Abstract: A system for radio frequency (RF) residual sideband (RSB) calibration includes a complex (in phase/quadrature (I/Q)) signal receiver, a signal generator configured to generate a transmit (Tx) signal, a first phase shifter operably coupled to the real signal transmitter, a first signal combiner configured to combine a receive (Rx) signal with the transmit (Tx) signal to generate a first combined signal, a second phase shifter configured to provide a selected phase shift to the first combined signal, and a complex downconverter configured to generate an in phase Rx signal and a quadrature Rx signal alternatively using an in phase LO signal and a quadrature LO signal to generate one or more signals indicative of relative Tx-Rx LO phase (?), amplitude (A), Tx LO I/Q phase mismatch (?), Rx I/Q amplitude mismatch (?), and Rx I/Q phase mismatch (?) at the output of the complex receiver.