Abstract: Disclosed are novel pharmaceutical salts and polymorphic forms of (R)—N-(5-((4-((5-chloro-4-fluoro-2-(2-hydroxypropan-2-yl)phenyl)amino)pyrimidin-2-yl)amino)-2-(3-(dimethylamino)pyrrolidin-1-yl)-4-methoxyphenyl)acrylamide (Compound I) that has inhibitory activities against ErbBs (e.g. EGFR or Her2) and/or BTK, especially mutant forms of ErbBs, and/or BTK. Further disclosed herein are the processes for the preparation of pharmaceutical salts and polymorphic forms of Compound I, and uses of such pharmaceutical salts and polymorphic forms of Compound I in inhibiting the ErbB or BTK.

Abstract: A downhole electric submersible pump (ESP) assembly. The downhole ESP assembly disposed comprises a permanent magnet motor (PMM) comprising a first drive shaft, a stator, and a rotor within the stator and comprising a core coupled to the first drive shaft, wherein the core retains a first permanent magnet element within a first magnet pocket defined by the core that extends axially parallel to the first drive shaft and retains a second permanent magnet element within a second magnet pocket defined by the core that extends axially parallel to the first drive shaft; a seal section having a second drive shaft coupled to the first drive shaft; and a pump assembly having a third drive shaft coupled to the second drive shaft.

Abstract: The present disclosure discloses a signal receiving apparatus having parameter optimization mechanism. A signal processing circuit processes a data signal according to at least one equalization parameter to generate an equalized data signal. A clock data recovery circuit performs clock data recovery on the equalized data signal according to a primary sampling signal and a primary threshold value to generate primary recovered data. A multi-sampling circuit performs clock data recovery on the equalized data signal according to secondary sampling signals and secondary threshold values to generate a plurality of pieces of secondary recovered data.

Abstract: This disclosure provides a LiDAR and a receiver and a method for receiving data of the LiDAR, and a computer-readable medium. A sampler of the receiver includes multiple sampling circuit groups corresponding to multiple sub-arrays of a photosensor array. When an echo spot falls on at least two sub-arrays, the sampler can sample electrical signals from the at least two sub-arrays by a sampling circuit group. A complete electrical signal from the echo spot can be sampled by a sampling circuit group. The integrity of an echo signal is ensured while the low power consumption of the LiDAR is maintained. The conflict between low power consumption of the LiDAR can be solved and integrity of an optical signal when alignment between an emitting end and a receiving end deviates.

Abstract: The present invention relates to the field of medicine. Specifically provided are a hemostatic sponge and a preparation method therefor. Components for preparing the hemostatic sponge comprise, by mass, 3-30 parts of a double bond-containing compound, 1-10 parts of chitosan, and 0.1-15 parts of a photoinitiator. Compared with existing commercial products, the hemostatic sponge of the present invention has a higher water absorption percentage and water absorption rate, and can quickly swell after absorbing water. When applied to a wound for hemostasis, the hemostatic sponge can quickly block the wound and achieve a hemostatic effect.

Abstract: Embodiments of the present disclosure provide a method and an apparatus for transmitting a feedback during wireless communication. A first apparatus (90) comprises means (910) for performing: receiving a transmission; transmitting a first feedback in response to the transmission. The first apparatus uses a plurality of resource blocks to form an interlace for the first feedback. The plurality of resource blocks comprises a first resource block, and at least one second resource block. A second resource block in the at least one second resource block is configured to be reusable for the first feedback, and a second feedback transmitted by a second apparatus. According to embodiments of the present disclosure, an improved manner for transmitting a feedback during wireless communication may be provided. Resource blocks may be reusable for more than one feedback from more than one apparatus. Thus, the number of required RBs to enable interlace/feedback may be reduced.

Abstract: A positioning method includes transmitting, by a first device, first information to one or more second devices, wherein the first information includes a positioning request signaling; transmitting, by the first device, a first positioning reference signal to the second devices, and receiving, by the first device, second positioning reference signals from the second devices; and obtaining, by the first device, a positioning calculation result of the first device according to a measurement result of the first positioning reference signal and measurement results of the second positioning reference signals, or receiving, by the first device, the positioning calculation result of the first device from one of the second devices.

Abstract: Provided is an arm-type aerial work platform. The platform includes a chassis mechanism and a walking drive mechanism. The chassis mechanism includes a front drive axle, a rear drive axle, front drive wheels on two sides of the front drive axle, and rear drive wheels on two sides of the rear drive axle. The walking drive mechanism includes a front transmission shaft, a rear transmission shaft, a transfer case, and a first drive motor. The first drive motor includes a first permanent magnet synchronization motor and a first alternating current driver, an input terminal of the first permanent magnet synchronization motor is electrically connected to the first alternating current driver, and an output terminal of the first permanent magnet synchronization motor is connected to an input terminal of the transfer case.

Abstract: Provided is a low-illumination image adaptive enhancement method, an apparatus thereof, a device and a storage medium. The method includes: inputting a low-illumination image to be enhanced into a pre-trained low-illumination image adaptive enhancement model to obtain an enhanced image. A method of training the low-illumination image adaptive enhancement model includes: acquiring a training set containing the low-illumination image and the corresponding reference image; constructing the low-illumination image adaptive enhancement model based on a Retinex algorithm. The low-illumination image adaptive enhancement model includes a projection module, an illumination component module, a reflectance component module and an enhancement module. The training set is used to train the low-illumination image adaptive enhancement model, and the trained low-illumination image adaptive enhancement model is obtained.

Abstract: Certain aspects relate to systems and techniques for an input device for controlling a robotic surgical tool. The input device can include a first pair of opposing links and a second pair of opposing links. The first pair of opposing links and second pair of opposing links can be arranged radially symmetrically. The input device can be configured to control operation of the robotic surgical tool.

Abstract: A display substrate and a display device are provided. The display substrate has a display area and a peripheral area surrounding the display area. The display substrate includes a first common voltage line, a second common voltage line and an integrated circuit. The first common voltage line is provided in the peripheral area and at least partially surrounds the display area; the second common voltage line is provided in the peripheral area, located on a side of the first common voltage line away from the display area, and at least partially surrounds the display area; the integrated circuit is provided in the peripheral area, and located on a first side of the display area, configured to provide first signals to the first and second common voltage line during a display stage, and provide second signals to the first and second common voltage line during a touch stage.

Abstract: A microwave hood system is provided. The microwave hood system includes a microwave oven enclosure defining a cooking cavity therein. A cooking component is positioned within the cooking cavity and configured to emit microwaves. The heating system defines a heating cavity therein, wherein the heating system is coupled to the microwave oven enclosure. A heating element is positioned in the heating cavity. The heating cavity reaches a temperature in a range from about 40° C. to about 80° C. when the heating element is in use. A broiler element is positioned within the heating cavity. The heating cavity reaches a temperature in a range from about hundred and 150° C. to about 300° C. when the broiler element is in use. A dual hood system is also coupled to the microwave hood system.

Abstract: Techniques for semiconductor pattern structure preservation are provided. In one embodiment, the techniques include depositing a metal oxide resist layer over a substrate, removing a portion of the metal oxide resist layer to form a set of pattern structures over the substrate, where the set of pattern structures includes a first pattern structure and a second pattern structure, depositing a treatment composition over the set of pattern structures, where the treatment composition includes an organic liquid and a set of polymeric compounds, tethering a first polymeric compound of the set of polymeric compounds to at least one of: a top surface of a first pattern structure, or a side surface of the first pattern structure, and tethering a second polymeric compound of the set of polymeric compounds to at least one of: a top surface of a second pattern structure, or a side surface of the second pattern structure.

Abstract: A novel biomimetic nano-sphere M@P-WI includes PLGA nanoparticles and the membrane of breast cancer EO771 cells. The PLGA nanoparticles are encapsulated within the membrane of breast cancer EO771 cells, and IR780 and DDR2 inhibitor WRG-28 are embedded in the PLGA nanoparticles. A method for preparing and applying the novel biomimetic nano-sphere M@P-WI is also provided. The method utilizes the aforementioned novel biomimetic nano-sphere M@P-WI, to trigger the conversion of light into heat energy upon near-infrared laser irradiation. This “burns” the tumor and induces specific immune responses within the body, inhibiting tumor recurrence and metastasis. Under the action of WRG-28, it promotes apoptosis of cancer-associated fibroblasts (CAF), reduces the remodeling of tumor extracellular matrix microenvironment, enhances the distribution of nanomaterials within the tumor, and restricts the invasiveness of breast cancer cells.

Abstract: A control circuit and method for an isolated switching-mode converter are disclosed. A secondary side controller receives and responds to a sleep control signal to generate a sleep request signal. When the sleep control signal is in a first state, the secondary-side controller enters a sleep mode and switches the sleep request signal to a third state. A primary-side controller responds to the sleep request signal in the third state and enters the sleep mode. In this way, the primary-side controller can enter the sleep mode in response to the entry of the secondary-side controller into the sleep mode. After the primary and second controllers enter the sleep mode, a majority of functional modules therein, as well as a signal isolator between the controllers, are turned off, effectively reducing standby power consumption of the system.

Abstract: Example embodiments relate to multi-channel dynamic weather estimations. An example embodiment includes a method. The method includes capturing, using a camera, an image of a first field of view of a surrounding environment from a first perspective. The method also includes capturing, using a light detection and ranging (lidar) device, a point cloud of a second field of view of the surrounding environment from a second perspective. Additionally, the method includes aligning, by a computing device, the image with the point cloud. Further, the method includes identifying, by the computing device, one or more high-intensity regions and one or more low-intensity regions of the surrounding environment. In addition, the method includes determining, by the computing device, a first figure of merit that characterizes environmental conditions of the surrounding environment and a second figure of merit that characterizes environmental conditions of the surrounding environment.

Abstract: One or more embodiments of the present disclosure relate to generation of map data. In these or other embodiments, the generation of the map data may include determining whether objects indicated by the sensor data are static objects or dynamic objects. Additionally or alternatively, sensor data may be removed or included in the map data based on determinations as to whether it corresponds to static objects or dynamic objects.

Abstract: Disclosed in the present disclosure are a CDN network request scheduling method, an electronic device, and a storage medium. The method includes: obtaining an original network request generated by the client for a target service; obtaining a first domain name rewriting rule corresponding to the target attribution information, and rewriting the original domain name by using the first domain name rewriting rule, to obtain a first domain name; updating the original domain name in the original network request by using the first domain name, to obtain a target network request; and sending the target network request to a target CDN server corresponding to the target CDN service provider identifier, so that the target CDN server obtains a target scheduling path corresponding to the target equipment room identifier, and forwards the target network request to a target equipment room according to the target scheduling path.

Abstract: A system including a first roofing material installed on the roof deck; a second roofing material installed on the roof deck, adjacent to the first roofing material, where the second roofing material includes: a first layer comprising silicone; and a first substrate, where the first layer partially covers a surface of the first substrate, thereby to provide at least a first area of the surface of the first substrate not covered by the first layer, where the first roofing material overlaps at least a portion of the first area; and a flashing material including silicone, where the flashing material covers a portion of each of: the first roofing material, and the first layer of the second roofing material.

Abstract: Systems and methods for modifying quality of service (QoS) flow for devices having particular device types based on cell congestion are provided. It is determined that a congestion level of a cell associated with a node exceeds a predetermined threshold, where the cell is providing communication to at least a first device having a first device type and a second device having a second device type. Prior to transmitting a packet to a component of a wireless communications network, a header associated with the packet is modified to include an indication that the congestion level of the cell exceeds the predetermined threshold. Based on the indication that the congestion level of the cell exceeds the predetermined threshold, a QoS flow is modified for devices having the first device type but not for devices having the second device type.