Patents by Inventor Zheng Rong

Zheng Rong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11065338
    Abstract: A composition includes a polysaccharide at least one retinoid linked to at least one monosaccharide subunit of the polysaccharide with a covalent linkage. The linkage being degradable by hydrolysis during digestion of the composition to provide controlled, delayed, and/or sustained delivery of the at least one retinoid upon enteral administration of the composition to a subject.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: July 20, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Songqi Gao, Krzysztof Palczewski, Zheng-Rong Lu
  • Patent number: 10925980
    Abstract: A molecular probe includes the following formula: P-L-C wherein P is a EDB-FN targeting peptide, C is a contrast agent; and L is a non-peptide linker that covalently links the peptide to the contrast agent.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: February 23, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Zheng-Rong Lu, Zheng Han
  • Publication number: 20200403333
    Abstract: A plug connector includes: an insulative housing including a main body, a reinforcement projecting forward from the main body, and a pair of baffle plates; and a printed circuit board partially received in the insulative housing, the printed circuit board extending forward from the main body and beyond the reinforcement, the reinforcement wrapping on the printed circuit board, wherein a width of a front end of the printed circuit board exposed outside the main body in a horizontal direction is greater than a width of the reinforcement, and a limiting groove is formed between the baffle plate and the printed circuit board for guiding the plug connector to mate with a socket connector.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Inventors: WEI MENG, ZHENG-RONG ZHU, JUN CHEN, YANG-TSUN HSU
  • Publication number: 20200403338
    Abstract: A plug connector used to mate with the socket connector includes: a housing; a printed circuit board received in the housing, the circuit print board having plural soldering points; and a cable electrically connected to the soldering points of the printed circuit board, wherein the soldering points are provided with glue blocks to protect a connection between the printed circuit board and the cable.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Inventors: WEI MENG, ZHENG-RONG ZHU, JUN CHEN, YANG-TSUN HSU
  • Publication number: 20200354315
    Abstract: A nanosized complex includes a nucleic acid and a compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or a polymer, a targeting group, a detectable moiety, or a linker, or a combination thereof, and at least one of R4 and R5 includes a retinoid or retinoid derivative that targets and/or binds to an interphotoreceptor retinoid binding protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 12, 2020
    Inventors: Zheng-Rong Lu, Da Sun, Rebecca Schur
  • Patent number: 10792374
    Abstract: A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or includes a polymer, a targeting group, or a detectable moiety, and at least one of R4 and R5 includes a targeting group that targets and/or binds to a retinal or visual protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: October 6, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Zheng-Rong Lu, Da Sun
  • Publication number: 20200274287
    Abstract: An electrical connector includes: a connector unit having a mating part, the mating part defining a front mating end; a sleeve enclosing the mating part and extending forwardly beyond the front mating end to define a receiving chamber; and an outer cover enclosing the sleeve and the connector unit, wherein the sleeve has a front portion containing the receiving chamber, and the outer cover is made of a material softer than the sleeve.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Inventors: ZHENG-RONG ZHU, JUN CHEN, JERRY WU
  • Patent number: 10653801
    Abstract: A compound includes at least one targeting peptide coupled to a detectable moiety. The targeting peptide binds to EDB-FN or EDA-FN and includes at least one of amino acid sequence selected from the group consisting of SEQ ID NOs: 1-30.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: May 19, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Zheng-Rong Lu, Zheng Han, Hui Zhu
  • Publication number: 20200121754
    Abstract: A pharmaceutical composition includes a retinylamine derivative having the following formula: where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond.
    Type: Application
    Filed: November 12, 2019
    Publication date: April 23, 2020
    Inventors: Krzysztof Palczewski, Zheng-Rong Lu
  • Publication number: 20200031865
    Abstract: A nanosized complex includes siRNA and a compound comprising formula (I):
    Type: Application
    Filed: September 30, 2019
    Publication date: January 30, 2020
    Inventors: Zheng-Rong Lu, Amita M. Vaidya
  • Patent number: 10471118
    Abstract: A pharmaceutical composition includes a retinylamine derivative having the following formula (I): where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: November 12, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Krzysztof Palczewski, Zheng-Rong Lu
  • Publication number: 20190282711
    Abstract: A compound includes at least one targeting peptide coupled to a detectable moiety. The targeting peptide binds to EDB-FN or EDA-FN and includes at least one of amino acid sequence selected from the group consisting of SEQ ID NOs: 1-30.
    Type: Application
    Filed: November 13, 2018
    Publication date: September 19, 2019
    Inventors: Zheng-Rong Lu, Zheng Han, Hui Zhu
  • Patent number: 10416463
    Abstract: A projecting unit includes a first light-source unit, a first digital micro-mirror unit, a second light-source unit, a second digital micro-mirror unit, a first prism, a first wide-angle lens, and a second wide-angle lens. The first light-source unit is configured to provide a first light beam. The first digital micro-mirror unit is configured to receive the first light beam and transform the first light beam into a first image signal. The second light-source unit is configured to provide a second light beam. The second digital micro-mirror unit is configured to receive the second light beam and transform the second light beam into a second image signal. The first prism is configured to receive and reflect the first and second image signals. The first wide-angle lens and the second wide-angle lens are configured to receive and project the first and second image signals reflected from the first prism respectively.
    Type: Grant
    Filed: August 13, 2017
    Date of Patent: September 17, 2019
    Assignees: Inventec Appliances (Pudong) Corporation, Inventec Appliances Corp., Inventec Appliances (JiangNing) Corporation
    Inventor: Zheng-Rong Zou
  • Patent number: 10392902
    Abstract: A technique facilitates the anchoring and use of a downhole tool. The technique may be utilized with operations in which fluid is pumped or otherwise flowed through a tubular to the downhole tool. The operations are performed after the downhole tool has been fixed relative to the wellbore and while the tubular remains connected to the downhole tool. In some operations, the downhole tool is manipulated from the surface via the tubular to control placement of the fluid flowing down through the tubular.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: August 27, 2019
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Michael Hayes Kenison, Zheng Rong Xu, Jeffrey Conner McCabe, Robert Bucher
  • Publication number: 20190216937
    Abstract: A composition includes a polysaccharide at least one retinoid linked to at least one monosaccharide subunit of the polysaccharide with a covalent linkage. The linkage being degradable by hydrolysis during digestion of the composition to provide controlled, delayed, and/or sustained delivery of the at least one retinoid upon enteral administration of the composition to a subject.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 18, 2019
    Inventors: Songqi Gao, Krzysztof Palczewski, Zheng-Rong Lu
  • Publication number: 20190091347
    Abstract: A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or includes a polymer, a targeting group, or a detectable moiety, and at least one of R4 and R5 includes a targeting group that targets and/or binds to a retinal or visual protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 11, 2015
    Publication date: March 28, 2019
    Inventors: Zheng-Rong Lu, Da Sun
  • Patent number: 10226536
    Abstract: A composition includes a polysaccharide at least one retinoid linked to at least one monosaccharide subunit of the polysaccharide with a covalent linkage. The linkage being degradable by hydrolysis during digestion of the composition to provide controlled, delayed, and/or sustained delivery of the at least one retinoid upon enteral administration of the composition to a subject.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: March 12, 2019
    Assignee: Case Western Reserve University
    Inventors: Songqi Gao, Krzysztof Palczewski, Zheng-Rong Lu
  • Patent number: 10211552
    Abstract: A cable connector assembly includes: an insulative base (1); plural contacts secured to the insulative base, each contact having a contacting portion, a terminating portion, and a securing portion between the contacting portion and the terminating portion; a cable including plural wires connected to the contacts, each wire having a center conductor; and an outer shell enclosing the insulative base and a part of the cable; wherein the contact terminating portion has a groove (2021) receiving the cable wire center conductor; and the cable wire center conductor extends to terminate perpendicularly to an associated contact. Plural interconnecting pieces each secured to an associated cable wire center conductor are also designed to replace direct connection of the cable wires to the contacts.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: February 19, 2019
    Assignee: FOXCONN INTERCONNECT TECHNOLOGY LIMITED
    Inventors: Zheng-Rong Zhu, Jun Chen, Jerry Wu
  • Patent number: 10124073
    Abstract: A compound includes at least one targeting peptide coupled to a detectable moiety. The targeting peptide binds to EDB-FN or EDA-FN and includes at least one of amino acid sequence selected from the group consisting of SEQ ID NOs: 1-30.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: November 13, 2018
    Assignee: Case Western Reserve University
    Inventors: Zheng-Rong Lu, Zheng Han, Hui Zhu
  • Publication number: 20180196270
    Abstract: A projecting unit includes a first light-source unit, a first digital micro-mirror unit, a second light-source unit, a second digital micro-mirror unit, a first prism, a first wide-angle lens, and a second wide-angle lens. The first light-source unit is configured to provide a first light beam. The first digital micro-mirror unit is configured to receive the first light beam and transform the first light beam into a first image signal. The second light-source unit is configured to provide a second light beam. The second digital micro-mirror unit is configured to receive the second light beam and transform the second light beam into a second image signal. The first prism is configured to receive and reflect the first and second image signals. The first wide-angle lens and the second wide-angle lens are configured to receive and project the first and second image signals reflected from the first prism respectively.
    Type: Application
    Filed: August 13, 2017
    Publication date: July 12, 2018
    Inventor: Zheng-Rong ZOU