Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

Abstract: Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

Abstract: A plug connector includes an insulating body having a mating portion, a ground terminal, and a latch member. A mating slot is disposed in the mating portion. The ground terminal has a first contacting portion protruding and extending into the mating slot, and a first tail portion. The latch member has a connecting portion and two locking arms located on two sides of the connecting portion. The first tail portion is in contact with the connecting portion, or in contact with the locking arms. Plate surfaces of the first tail portions are perpendicular to plate surfaces of the locking arms. The locking arms are located on two sides of the mating portion and respectively have a locking portion protruding and extending into the mating slot. The locking portions are used for engaging with buckling slots of a tongue.

Abstract: A plug connector includes a metal shell, an insulating body retained in the metal shell and having a mating portion, multiple terminals, and at least one grounding elastic piece. The mating portion is recessed from front to back to form a mating slot. The terminals include contacting portions arranged in a row on upper and lower opposite sides of the mating slot. The terminals include at least one ground terminal formed by blanking a sheet metal. The plate surface of the ground terminal is arranged vertically. The grounding elastic piece is formed by blanking a sheet metal. The plate surface of the grounding elastic piece is arranged in parallel to the plate surface of the ground terminal, and the two are connected electrically to each other. A conducting portion is formed on the cutting surface of the grounding elastic piece, and in contact with the metal shell.

Abstract: A vehicle information and environmental monitoring compound vehicle system is provided, including a sensor device used as a mobile sensor for collecting sensory data of roads, and the sensor device integrates various sensor modules and the second-generation on board computer diagnostic system serial port. The sensor device also integrates a long-distance low-power Internet of Things (LoRa) communication protocol, which can transmit data through the long-distance low-power Internet of Things gateway, and upload data to the cloud platform based on algorithm. The results of the analysis can establish a wide range of traffic congestion model through the detection information of traffic flow, and traffic density. The use of pixel-based measurement methods can quantify the urban road temperature, establish the urban heat island effect model, analyze the influence of temperature and humidity on the disease spread, establish the disease diffusion model, and display the sensor data in the graphical user interface.

Abstract: Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

Abstract: Disclosed are a method and a device for testing a defect based on an ultrasonic Lamb wave tomography. The method includes: partitioning an imaging area of a material to be tested into grids; exciting electromagnetic acoustic transducers for emitting to emit Lamb waves with a A0 mode in all directions, and electromagnetic acoustic transducers for receiving to receive the Lamb waves; obtaining a time-frequency analysis result and recording time-of-flights of testing waves; determining a first slowness of each grid to obtain a first defect area; establishing an extrapolation formula according to the first defect area, and iterating the extrapolation formula to trace and revise paths of the Lamb waves until a better imaging precision is obtained.

Abstract: The present disclosure involves systems, software, and computer implemented methods for performing dynamic topology switch in a failover operation. In one example, a failover of a first node is determined. The first node includes a first data server and a first replication server. At least one user application connects to the first data server prior to the failover of the first node. In response to the determined failover, the at least one user application is connected to a second data server of a second node. The second node includes the second data server and a second replication server. Prior to the failover of the first node, a data replication topology of the second node is a remote topology. During the failover, if the first replication server on the first node is down, the data replication topology of the second node is switched from the remote topology to a local topology.

Abstract: An inner detecting device for subsea oil and gas pipeline includes a support shaft defining a sealed chamber therein; a packer cup coupled to the support shaft; a hinge assembly coupled to the support shaft, swinging with respect to the support shaft in a radial direction and sliding with respect to the support shaft in an axial direction; a magnetic detector connected to the hinge assembly to move with respect to the support shaft in the radial and axial directions, and the magnetic detector tending to move away from the support shaft in the radial direction; a battery pack; an electric recorder electrically connected to the battery pack; and a mileage recorder recording a travel distance of the inner detecting device within the pipeline.

Abstract: An electrical connector assembly includes an electrical connector and a mating connector that are mutually inserted. The mating connector includes a socket and a metal shell having an insertion end protruding from the socket formed with an opening. The electrical connector includes an insulating body and an assisting member. The insulating body includes a main body and a mating portion. An upper surface of the main body is higher than that of the mating portion. An interface is formed in the front end of the main body and is positioned behind the socket. The mating portion is smaller than the opening. The assisting member covers the insulating body. A front end of the assisting member guides the insertion of the insertion end. An accommodation space is formed between the assisting member and the main body to receive only the metal shell.

Abstract: A connecting device configured to electrically connect a solenoid valve to a manifold base includes a housing and two spaced-apart conductive bodies disposed inside the housing. The housing has a valve-connecting portion configured to be connected to the solenoid valve, and a base-connecting portion configured to be connected to the manifold base. Each conductive body has a first conductive portion configured to electrically connect with the solenoid valve, a second conductive portion configured to electrically connect with the manifold base, and an electrical connecting portion connected between the first and second conductive portions.

Abstract: A plug connector includes an insulating body having a mating portion, a ground terminal, and a latch member. A mating slot is disposed in the mating portion. The ground terminal has a first contacting portion protruding and extending into the mating slot, and a first tail portion. The latch member has a connecting portion and two locking arms located on two sides of the connecting portion. The first tail portion is in contact with the connecting portion, or in contact with the locking arms. Plate surfaces of the first tail portions are perpendicular to plate surfaces of the locking arms. The locking arms are located on two sides of the mating portion and respectively have a locking portion protruding and extending into the mating slot. The locking portions are used for engaging with buckling slots of a tongue.

Abstract: A plug connector includes a metal shell, an insulating body retained in the metal shell and having a mating portion, multiple terminals, and at least one grounding elastic piece. The mating portion is recessed from front to back to form a mating slot. The terminals include contacting portions arranged in a row on upper and lower opposite sides of the mating slot. The terminals include at least one ground terminal formed by blanking a sheet metal. The plate surface of the ground terminal is arranged vertically. The grounding elastic piece is formed by blanking a sheet metal. The plate surface of the grounding elastic piece is arranged in parallel to the plate surface of the ground terminal, and the two are connected electrically to each other. A conducting portion is formed on the cutting surface of the grounding elastic piece, and in contact with the metal shell.

Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

Abstract: Disclosed herein are system, method, and computer program product embodiments for providing read queries latch-free access to an index page. In an embodiment, a processor receives a request from a read query to access one or more records of an index page. The index page includes an update pointer and a slot array. The processor locates one or more updates prepended to the index page by locating a most recently prepended update indicated by the update pointer. Then, the processor generates a local offset table with entries in the slot array and the located one or more updates. The generated local offset table enables the processor to provide the read query access to the one or more records of the index page.

Abstract: System, method, computer program product embodiments and combinations and sub-combinations thereof for data replication in a database system environment are described. In an aspect, the data replication includes grouping, in-memory, a plurality of transactions to be replicated as a single transaction from a source database system to a target database system. A plurality of net row changes is compiled for the plurality of transactions, and data inconsistency detection and resolution within a command application order are performed. The plurality of net row changes are organized in segments and the segments can be applied simultaneously in bulk to the target database system.

Abstract: A method, device and system for selecting a security algorithm are provided. The method includes: a core network receives an attachment request initiated to a broadband cluster network by a first terminal (UE), wherein the attachment request carries first security capability information supported by the first UE; the core network determines a group to which the first UE belongs, and obtains security capability information of each second UE in the group; and the core network selects a security algorithm supported by both the security capability information of the first UE and the security capability information of each second UE; and sends the selected security algorithm to the first UE as a security algorithm of the group.

Abstract: Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

Abstract: A circuit board includes a circuit board plate, a conductive ring, a solder mask and at least one insulating pad. The circuit board plate includes a surface and a conductive through hole passing through the surface and the circuit board plate, wherein the conductive through hole have a conductive layer disposed on a wall thereof. The conductive ring on the surface surrounds an opening of the conductive through hole on the surface and electrically connects to the conductive layer. The solder mask is disposed on the surface. The conductive ring is exposed outside of the solder mask. The insulating pad has a thickness. The first surface of the insulating pad is adapted to contact the solder mask or the surface and sited at periphery of the conductive ring. The second surface of the insulating pad is adapted for spacing a distance between a solder coating tool and the solder mask.