Patents by Inventor Zhigang He

Zhigang He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080142498
    Abstract: This type of product declare a multifunction safe electric pressure cooker comprises lid, outer body, warm-keeping Container, control panel, inner tank, sealant washer, heating plate under the inner tank, control device. The control device comprises the control circuit, pressure switch, temperature control device. The pressure switch and the temperature control device are under the warm-keeping Container. On the lid there are floating valve, pressure discharging valve, safety valve. Between the heating plate and the warm-keeping Container there is a spring device. Under the said heating plate there is a pole. The characteristic of it is that the control device comprises a sensor under the heating plate to sense whether has an inner tank in. Between the lid and the body sets a lid safety control switch that connected to the control circuit.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Zhigang He, Zhibin Huang
  • Publication number: 20080031911
    Abstract: Regeneration of a lesioned CNS axon of a mature neuron, determined to be subject to regeneration inhibition by Smad2/3 signaling, is promoted by contacting the neuron with an inhibitor of Smad2/3 signaling sufficient to promote regeneration of the axon.
    Type: Application
    Filed: August 6, 2006
    Publication date: February 7, 2008
    Inventors: Zhigang He, Fan Wang
  • Patent number: 7309485
    Abstract: Oligodendrocyte-myelin glycoprotein (OMgp)-specific binding agents are used to reduce OMgp-mediated axon growth inhibition. Mixtures of axons and OMgp and mixtures of Nogo receptor (NgR) and OMgp are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to OMgp and promoting axon regeneration.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: December 18, 2007
    Assignee: Children's Medical Center Corporation
    Inventors: Zhigang He, Kevin C. Wang, Vuk Koprivica, Jieun A. Kim
  • Patent number: 7238659
    Abstract: Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.
    Type: Grant
    Filed: November 19, 2005
    Date of Patent: July 3, 2007
    Assignees: Children's Medical Center Corporation, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Zhigang He, Qiwei Zhai, Jing Wang, Ryan Watts, Eric Hoopfer, Liqun Luo
  • Publication number: 20070014792
    Abstract: Compositions and methods for promoting neural regeneration in a patient determined to have a lesion in a mature CNS neuron are disclosed. The method comprises the step of contacting the neuron with an EGFR inhibitor sufficient to promote regeneration of the neuron.
    Type: Application
    Filed: July 12, 2005
    Publication date: January 18, 2007
    Inventors: Zhigang He, Vuk Koprivica
  • Publication number: 20060211743
    Abstract: Neural degeneration is reduced in a patient determined to be suffering from chronic neurodegeneration by administering to the patient an effective amount of 3-pyridinecarboxamide (nicotinamide) and detecting a resultant decrease in the neural degeneration.
    Type: Application
    Filed: March 21, 2005
    Publication date: September 21, 2006
    Inventors: Zhigang He, Jing Wang, Ying Chen, Shijniro Kaneko
  • Publication number: 20060211744
    Abstract: Neural degeneration is reduced in a patient determined to be suffering from chronic neurodegeneration by administering to the patient an effective amount of 3-pyridinecarboxamide (nicotinamide) and detecting a resultant decrease in the neural degeneration.
    Type: Application
    Filed: December 5, 2005
    Publication date: September 21, 2006
    Inventors: Zhigang He, Jing Wang, Ying Chen, Shijniro Kaneko
  • Publication number: 20060104973
    Abstract: Inhibitors of Nogo Receptor (NgR)-p75 binding are used to reduce NgR-p75 binding mediated axon growth inhibition. Mixtures of NgR and p75 are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to p75 and promoting axon regeneration.
    Type: Application
    Filed: December 27, 2005
    Publication date: May 18, 2006
    Inventors: Zhigang He, Kevin Wang, Jieun Kim
  • Publication number: 20060074028
    Abstract: Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.
    Type: Application
    Filed: November 19, 2005
    Publication date: April 6, 2006
    Inventors: Zhigang He, Qiwei Zhai, Jing Wang, Ryan Watts, Eric Hoopfer, Liqun Luo
  • Patent number: 7012063
    Abstract: Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: March 14, 2006
    Assignee: Children's Medical Center Corporation
    Inventors: Zhigang He, Qiwei Zhai, Jing Wang, Ryan Watts, Eric Hoopfer, Liqun Luo
  • Publication number: 20050130877
    Abstract: Regenerative growth of an adult mammalian central nervous system neuron axon subject to growth inhibition by endogenous, myelin growth repulsion factors is promoted by delivering to the axon a therapeutically effective amount of a specific inhibitor of protein kinase C, whereby regenerative growth of the axon is promoted and a resultant promotion of the regenerative growth of the axon is detected.
    Type: Application
    Filed: November 9, 2004
    Publication date: June 16, 2005
    Inventors: Zhigang He, Vuk Koprivica, Rajeev Sivasankaran
  • Publication number: 20040254118
    Abstract: Reduced degeneration of an axon predetermined to be subject to degenerative neuropathy in a term patient is effected by contacting the axon in situ with an effective amount of a ubiquitin-proteasome system (UPS) inhibitor sufficient to reduce degeneration of the axon; and detecting a resultant reduction in the degeneration of the axon in situ.
    Type: Application
    Filed: June 13, 2003
    Publication date: December 16, 2004
    Applicants: Children's Medical Center Corporation, The Board of Trustees for the Leland Stanford Jr. University
    Inventors: Zhigang He, Qiwei Zhai, Jing Wang, Ryan Watts, Eric Hoopfer, Liqun Luo
  • Patent number: 6815450
    Abstract: Regenerative growth of an adult mammalian central nervous system neuron axon subject to growth inhibition by endogenous, myelin growth repulsion factors is promoted by delivering to the axon a therapeutically effective amount of a specific inhibitor of protein kinase C, whereby regenerative growth of the axon is promoted and a resultant promotion of the regenerative growth of the axon is detected.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: November 9, 2004
    Assignee: Children's Medical Center Corporation
    Inventors: Zhigang He, Vuk Koprivica, Rajeev Sivasankaran
  • Publication number: 20040215563
    Abstract: A system for collocating materials includes an application server (115), and a database server (117) connected with the server via a network (107). The application server manages shipment procedures, and includes: a bill generating module (307) for generating a shipment bill in accordance with a requirement of a client; a material collocating module (303) for collocating materials in accordance with the shipment bill; and a processing module (308) for management different shipment. The database server stores basic data related to collocating materials of the application server. A related method includes the steps of: (a) generating a shipment bill; (b) reading a client code from the shipment bill; (c) reading a material code and a quantity from the shipment bill; (d) selecting a supplier in accordance with the client code and the material code; (e) assigning one or more area codes and unit codes to the material; and (f) managing shipment procedure.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 28, 2004
    Inventors: Sheng Chi Luo, Fucheng Wang, ZhiGang He, Andong Lee, Hua Xu, Jinli Ji
  • Publication number: 20040039576
    Abstract: A sales data exchange system and method for exchanging data with customers and suppliers by integrating data in an internal information system and EDI data received. The sales data exchange system (1) includes a main database (16) for storing sales data; an EDI data translator (14) for converting a format of the sales data; an EDI data input and output device (13) for sending and receiving the sales data in EDI format; and a plurality of user clients (11) provided for users to send and receive EDI data. Each of the user clients includes a sales order control unit (12) for handling the sales data, the sales order control unit including an order management module (120) for managing sales orders data, a shipping management module (122) for managing shipping data, and an invoice management module (124) for managing invoice data, and an inventory management module (126).
    Type: Application
    Filed: June 13, 2002
    Publication date: February 26, 2004
    Inventors: ZhiGang He, Simon Shen, Michael Hsu, TangHao Chu
  • Publication number: 20040029169
    Abstract: Inhibitors of Nogo Receptor (NgR)-p75 binding are used to reduce NgR-p75 binding mediated axon growth inhibition. Mixtures of NgR and p75 are used in pharmaceutical screens to characterize agents as inhibiting binding of NgR to p75 and promoting axon regeneration.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 12, 2004
    Applicant: Children's Medical Center Corporation
    Inventors: Zhigang He, Kevin C. Wang, Jieun A. Kim
  • Publication number: 20030233291
    Abstract: A system and method for managing cargo shipment according to inventory status and a received purchase order. The system interchanges data with a carrier MIS (5) and a customer MIS (4) via an EDI value added network (2). The system includes a main database (16) for storing purchase order data and inventory data, and a plurality of user clients (11) electronically connected with the main database. Each user client includes a shipment data management unit (12) for handling the data stored in the main database. The shipment data management unit includes a purchase order data search module (120) for users to search for the data on purchase orders set by customers, an inventory data search module (122) for users to search for inventory data relevant to the purchase orders, and a shipment schedule module (124) for scheduling shipment of cargo according to the purchase order data and the inventory data.
    Type: Application
    Filed: June 13, 2002
    Publication date: December 18, 2003
    Inventors: Michael Hsu, TangHao Chu, ZhiGang He, Simon Shen, Bao Zhong Xu
  • Publication number: 20030233293
    Abstract: A system and method for putting in-warehouse articles in a correct location in a warehouse (9), and for quickly retrieving out-warehouse articles from the warehouse. The system includes: a central management server (1) that includes a database (10) for storing in-warehouse article data, inventory data, out-warehouse article data and storage location information; a plurality of computing devices (3) located in different warehouses and linking to the central management server via an intranet (2); and a plurality of barcode printers (4) respectively linking to the plurality of computing devices for printing inventory data barcodes (14) that are attached to pallets (12).
    Type: Application
    Filed: July 10, 2002
    Publication date: December 18, 2003
    Inventors: Michael Hsu, Yarchen Wen, ZhiGang He, Simon Shen, Taylor Liu
  • Patent number: 6664266
    Abstract: Regenerative growth of an adult mammalian central nervous system neuron axon subject to growth inhibition by endogenous, myelin growth repulsion factors is promoted by delivering to the axon a therapeutically effective amount of a specific inhibitor of protein kinase C, whereby regenerative growth of the axon is promoted and a resultant promotion of the regenerative growth of the axon is detected.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: December 16, 2003
    Assignee: Children's Medical Center Corporation
    Inventors: Zhigang He, Vuk Koprivica, Rajeev Sivasankaran
  • Patent number: 6623738
    Abstract: The invention provides methods and compositions relating to two classes of semaphorin receptors, SR1 and SR2. The polypeptides may be produced recombinantly from transformed host cells from the disclosed SR encoding nucleic acids or purified from human cells. The invention provides isolated SR hybridization probes and primers, capable of specifically hybridizing with the disclosed SR genes. SR-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: September 23, 2003
    Assignee: The Regents of the University of California
    Inventors: Marc Tessier-Lavigne, Zhigang He, Hang Chen