Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.

Abstract: Methods, systems, and devices are described for wireless communication. A wireless device such as an in-vehicle system (IVS) may transmit an emergency call (eCall) message to a third party eCall server using a communication session which may be packet based or circuit based. The eCall message may include session information and telematics data. The third party eCall server may relay the session information and telematics data to a public safety answering point (PSAP). For example, the third party eCall server may generate an automatic text-to-speech message that is transmitted to the PSAP over a public communications network. In some cases, the third party eCall server may transmit a response to the wireless device including metadata based on the telematics data transmitted in the eCall message. The eCall message may also include a call-back number, and the PSAP may contact the wireless device directly using the call-back number.

Abstract: The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein W, B, n, m, A?, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.

Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: A geographic position information-based community interconnection method may comprise creating a community network using geographic position information and identity information as network nodes; when a user terminal logs onto the community network for the first time, registration and authentication may need to be completed. The method may include receiving information and/or services for interaction, and uploading the received information and/or services to the community network server. The user terminal may acquire desired information and/or services by searching the information and/or services stored in the visible space.

Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein X1, X2, X3, R2, R3, R4, R5, and Y are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.

Abstract: Methods, systems, and devices are described for wireless communication. A wireless device such as an in-vehicle system (IVS) may transmit an emergency call (eCall) message to a third party eCall server using a communication session which may be packet based or circuit based. The eCall message may include session information and telematics data. The third party eCall server may relay the session information and telematics data to a public safety answering point (PSAP). For example, the third party eCall server may generate an automatic text-to-speech message that is transmitted to the PSAP over a public communications network. In some cases, the third party eCall server may transmit a response to the wireless device including metadata based on the telematics data transmitted in the eCall message. The eCall message may also include a call-back number, and the PSAP may contact the wireless device directly using the call-back number.

Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: Methods and apparatuses are provided for facilitating authentication of access terminal identities and for recording a usage relationship between a valid access terminal identity and a user identity. An access terminal and a validation server are both provisioned with corresponding validation keys. The access terminal may determine that a user identity is not recorded for use with the access terminal, and may send a report message to report a usage relationship between the access terminal identity and the user identity, where the report message is signed with a signature based on the validation key. The validation server authenticates the signature using the validation key in the validation server. The validation server may record the usage relationship between the authenticated access terminal identity and the user identity in a database, which database records may be employed to determine whether an access terminal requesting network access is authorized or unauthorized.

Abstract: A method for controlling an electronic device. The method comprises: a control terminal starting a service of a self-organizing network, and initializing and displaying an information table of electronic devices currently on the self-organizing network; sending, based on an electronic device selected from the electronic device information table by a user, an update request to the electronic device through a network route of the self-organizing network; receiving device function information fed back by the electronic device according to the update request, and establishing a function calling table according to the device function information; and displaying a control UI of the remote control terminal according to the function calling table and sending an execution instruction to the electronic device according to a function item selected by the user. A control terminal and a system for controlling the electronic device.

Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein X1, X2, X3, R2, R3, R4, R5, and Y are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.

Abstract: Methods and devices for dynamic VSIM provisioning on a multi-SIM wireless device having a first SIM as a Universal Integrated Circuit Card (UICC) and a virtual SIM (VSIM). A provisioning server may receive updated information from the wireless device, and based at least partially on the received information, determine whether the SIM profile on the VSIM of the wireless device should be changed. To change the SIM profile, the provisioning server may determine whether remote credential management procedures are enabled. If so, the provisioning server may select a new SIM profile from a plurality of SIM profiles, and provision the new SIM profile in the VSIM using remote credential management procedures. If remote credential management procedures are unavailable, the provisioning server may select a remote SIM from a plurality of remote SIMs associated with the provisioning server, and run the remote SIM to execute authentication processes for the wireless device.

Abstract: A method for controlling an electronic device. The method comprises: a control terminal starting a service of a self-organizing network, and initializing and displaying an information table of electronic devices currently on the self-organizing network; sending, based on an electronic device selected from the electronic device information table by a user, an update request to the electronic device through a network route of the self-organizing network; receiving device function information fed back by the electronic device according to the update request, and establishing a function calling table according to the device function information; and displaying a control UI of the remote control terminal according to the function calling table and sending an execution instruction to the electronic device according to a function item selected by the user. A control terminal and a system for controlling the electronic device.

Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein X1, X2, X3, R2, R3, R4, R5, and Y are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.

Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:

Abstract: The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, or a mixture thereof, wherein n, m, q, A?, W1, W2, W3, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.

Abstract: The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein W, B, n, m, A?, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.