Abstract: A display substrate, a display panel and a display apparatus are provided. The display substrate includes a base substrate, a first display region, and a second display region, and a light transmittance of the first display region is greater than that of the second display region A plurality of sub-pixels are arranged on the base substrate and in the first display region, wherein the sub-pixels include a first pixel driving circuit and a first light-emitting device, and the first pixel driving circuit includes a compensation transistor, a switching transistor, and a light-emitting device initialization transistor each having an active layer. A scan signal line is provided in the first display region. An orthographic projection of the scan signal line on the base substrate overlaps with that of the active layer of each of the compensation transistor, the switching transistor and the light-emitting device initialization transistor on the base substrate.

Abstract: A display substrate includes first and second display regions, and a base substrate. A plurality of sub-pixels are arranged on a side of the base substrate, where the-sub-pixels include a first pixel driving circuit and a first light-emitting device connected to each other in the first display region, and the first pixel driving circuit includes at least a compensation transistor, a switching transistor, and a light-emitting device initialization transistor each having an active layer. A scan signal line is provided in the first display region. An orthographic projection of the scan signal line on the base substrate overlaps with that of the active layer of each of the compensation transistor and the light-emitting device initialization transistor, or that of the active layer of each of the switching transistor and the light-emitting device initialization transistor on the base substrate.

Abstract: A display panel, a driving method and a display apparatus are disclosed. The display panel includes: a substrate, an active semiconductor layer, a gate insulating layer, a first conductive layer, an interlayer dielectric layer, a second conductive layer, a first interlayer insulating layer, a third conductive layer including a plurality of first signal lines, a second interlayer insulating layer, a fourth conductive layer including a plurality of second signal lines stacked in that order. Orthographic projections of the first signal lines on the substrate and orthographic projections of the second signal lines on the substrate are arranged in an intersecting manner.

Abstract: A shift register, comprising an input circuit, a first control circuit, a second control circuit and an output circuit. The input circuit is configured to transmit a first voltage signal from a first voltage signal terminal to a first node under the control of an input signal from a signal input terminal. The first control circuit is configured to transmit a second voltage signal from a second voltage signal terminal to a second node under the control of a first clock signal from a first clock signal terminal and the voltage of the first node. The second control circuit is configured to transmit a second clock signal from a second clock signal terminal to a third node under the control of the voltage of the second node. The output circuit is configured to transmit the first voltage signal from the first voltage signal terminal to a scan signal output terminal under the control of the voltage of the third node.

Abstract: Provided is a tetanus toxin protein variant, the tetanus toxin protein variant comprising a C fragment of the tetanus toxin protein and a partial fragment of a translocation region of the tetanus toxin protein. Further provided is a proteoglycan conjugate, the proteoglycan conjugate comprising a polysaccharide from Streptococcus pneumoniae and a truncated tetanus toxin protein. Also provided is a method for improving immunogenicity, the method comprising the following steps: providing a proteoglycan conjugate comprising a polysaccharide from Streptococcus pneumoniae and a truncated tetanus toxin protein.

Abstract: A linker peptide for constructing a fusion protein. The linker peptide comprises a flexible peptide and a rigid peptide. The flexible peptide consists of one or more flexible units. The rigid peptide consists of one or more rigid units. The flexible unit comprises two or more amino acid residues selected from Gly, Ser, Ala, and Thr. The rigid unit comprises a human chorionic gonadotropin ?-subunit carboxy-terminal peptide (CTP) bearing a plurality of glycosylation sites. The linker peptide can more effectively eliminate mutual steric hindrance of two fusion molecules, decreasing a reduction/loss of polymerization or activity resulting from improper folding of an active protein or a conformational change. On the other hand, the negatively charged, highly sialylated CTP can resist renal clearance, further prolonging a half-life of a fused molecule and enhancing bioavailability of a fused protein.

Abstract: Provided is a shift register. The shift register comprising: an input circuit, an intermediate circuit and an output circuit; the input circuit is connected to a first power supply terminal, a second power supply terminal, an input voltage terminal and a first clock signal terminal, and the input circuit is configured to output an intermediate input signal to the intermediate circuit; the intermediate circuit is connected to the first power supply terminal, the second power supply terminal and a second clock signal terminal, and the intermediate circuit is configured to output a first node signal to the output circuit; and the output circuit is connected to the first power supply terminal, the second power supply terminal, a first output terminal and a second output terminal, and the output circuit is configured to output a first output signal and a second output signal.

Abstract: Provided are a display panel and a display apparatus. The display panel includes: a substrate; a plurality of touch electrodes at least partially located on the substrate in a display area; a plurality of touch leads located on the substrate, one ends of the touch leads being coupled to the touch electrodes, and the other ends of the touch leads being located in a peripheral area; a plurality of data leads located on the substrate in the peripheral area; and a plurality of shield lines located on the substrate in the peripheral area, orthographic projections of the shield lines on the substrate being located between orthographic projections of the touch leads on the substrate and orthographic projections of the data leads on the substrate, and at least two of the plurality of shield lines in the display panel being connected to each other in a shorted manner.

Abstract: A display substrate, a display panel and a display apparatus are provided. The display substrate includes a base substrate, a first display region, and a second display region, and a light transmittance of the first display region is greater than that of the second display region A plurality of sub-pixels are arranged on the base substrate and in the first display region, wherein the sub-pixels include a first pixel driving circuit and a first light-emitting device, and the first pixel driving circuit includes a compensation transistor, a switching transistor, and a light-emitting device initialization transistor each having an active layer. A scan signal line is provided in the first display region . An orthographic projection of the scan signal line on the base substrate overlaps with that of the active layer of each of the compensation transistor, the switching transistor and the light-emitting device initialization transistor on the base substrate.

Abstract: A shift register circuit (100) includes: an input circuit (110), a reset circuit (180), a first control circuit (120), a second control circuit (130), a third control circuit (140), a fourth control circuit (150), a fifth control circuit (160), a first output circuit (170a), a second output circuit (170b) and a third output circuit (170c). The shift register circuit (100) is configured to be capable of providing three different output signals as three different gate driving signals required to drive a pixel array of a display panel (810).

Abstract: A shift register, comprising an input circuit, a first control circuit, a second control circuit and an output circuit. The input circuit is configured to transmit a first voltage signal from a first voltage signal terminal to a first node under the control of an input signal from a signal input terminal. The first control circuit is configured to transmit a second voltage signal from a second voltage signal terminal to a second node under the control of a first clock signal from a first clock signal terminal and the voltage of the first node. The second control circuit is configured to transmit a second clock signal from a second clock signal terminal to a third node under the control of the voltage of the second node. The output circuit is configured to transmit the first voltage signal from the first voltage signal terminal to a scan signal output terminal under the control of the voltage of the third node.

Abstract: The invention provides an antibody and/or an antigen binding fragment that binds to NGF, and the amino acid sequences of the heavy chain and light chain variable regions of the antibody. The NGF antibody and/or its antigen binding fragment provided by the invention has high affinity for NGF and can effectively block the binding between NGF receptor and NGF. This antibody and/or its antigen binding fragment can inhibit the binding activity of NGF and its receptor in vitro, and is suitable for the treatment of pain diseases which are related to the haughty expression or increased expression of NGF.

Abstract: The present disclosure provides a shift register circuit, including A shift register circuit (100) includes: an input circuit (110), a reset circuit (180), a first control circuit (120), a second control circuit (130), a third control circuit (140), a fourth control circuit (150), a fifth control circuit (160), a first output circuit (170a), a second output circuit (170b) and a third output circuit (170c). The shift register circuit (100) is configured to be capable of providing three different output signals as three different gate driving signals required to drive a pixel array of a display panel (810).

Abstract: An electrical connector includes at least one terminal assembly. The terminal assembly includes: a first signal terminal and a second signal terminal being narrow-edge coupled; and an insulating block fixing the first signal terminal and the second signal terminal. A length of the first signal terminal is greater than a length of the second signal terminal. A first connecting portion of the first signal terminal is provided with at least one exposing area, which is exposed to the insulating block and exposed in air medium. The first connecting portion has at least one widening portion and at least one narrow portion connected to each other along a length direction thereof. A width of the widening portion is greater than a width of the narrow portion. The exposing area is provided at the widening portion. A second connecting portion of the second signal terminal is completely wrapped in the insulating block.

Abstract: A method for testing software applications in a system under test (SUT) includes building a reference model of the SUT that defines a computer-based neural network. The method includes training the reference model using input data and corresponding output data generated by the SUT, selecting an output value within a domain of possible output values of the SUT representing an output that is not represented in the output data used to train the reference model, applying the selected output value to the reference model, and tracing the selected output through the reference model to identify test input values that when input to the reference model, produce the selected output value. The method can further include using the identified test input values to test the system under test.

Abstract: A pixel drive circuit, a driving method thereof, and a display panel are provided. The pixel drive circuit comprises a drive transistor, a data writing circuit, a compensation circuit, a light-emitting control circuit, a storage circuit, a first transistor and a second transistor. The first electrode of the drive transistor is connected to the first node, the second electrode thereof is connected to the second node, and the gate thereof is connected to the third node; the data writing circuit is connected to the first node and the data signal terminal; the compensation circuit is connected to the second node and the third node; the light-emitting control circuit is connected to the drive transistor, the first power supply terminal, the light-emitting unit and the enable signal terminal; the storage circuit is connected between the first power supply terminal and the third node.

Abstract: Pixel circuit, driving method thereof and display device are provided. Pixel circuit includes driving transistor, storage capacitor, voltage-stabilizing capacitor, data writing sub-circuit, threshold compensation sub-circuit, reset sub-circuit, sensing sub-circuit and light-emitting control sub-circuit. First terminal of storage capacitor, gate electrode of driving transistor, first terminal of reset sub-circuit and first terminal of threshold compensation sub-circuit are coupled to first node. Second terminal of storage capacitor, first terminal of sensing sub-circuit and first electrode of light-emitting device are coupled to second node. Sensing sub-circuit is configured to transmit initial voltage signal on reference line to second node during reset sub-periods of sensing period and display period; and transmit voltage at second node to reference line during light-emitting sub-period of sensing period to read voltage at second node.

Abstract: A displaying base plate and a displaying device, wherein the displaying base plate includes a displaying region, a binding region, and a fanout region located between the displaying region and the binding region, the fanout region includes a touch-controlling lead wire, a data lead wire, and at least one shielding wire located between the touch-controlling lead wire and the data lead wire, the at least one shielding wire includes a first shielding wire, and the first shielding wire is earthed or is connected to a constant electric potential.

Abstract: A pixel circuit includes: pixel units, wherein each pixel unit includes a light-emitting element and a pixel driving circuit, the pixel driving circuit and the light-emitting element are electrically connected to a first node; a first compensation sub-circuit electrically connected to each pixel driving circuit, and configured to provide an initialization signal to the pixel driving circuit, obtain a voltage at the first node when the light-emitting element emits light via the pixel driving circuit, and generate a compensation data signal based on the voltage at the first node; and a second compensation sub-circuit electrically connected to each pixel driving circuit and configured to keep the voltage at the first node within a set operating voltage range of the light-emitting element. The pixel driving circuit is further configured to initialize the first node based on the initialization signal, and use the compensation data signal to drive the light-emitting element.

Abstract: The present disclosure relates to a display driving device, a display apparatus, a display driving method and a signal controlling device. The signal controlling device includes a scanning signal controlling device configured to output a scanning signal that initiates a scanning of a pixel array, and an image data segmenting device configured to receive the scanning signal and a data signal representing a frame of image from a data source, and to segment the data signal in response to the scanning signal to output a first set of image data signals and a second set of image data signals. The first set of image data signals comprises data information of a first set of column pixels in the frame of image and the second set of image data signals comprises data information of a second set of column pixels in the frame of image.