Methods for in vitro expansion and transdifferentiation of human pancreatic acinar cells into insulin-producing cells

This invention relates, e.g., to a method for expanding mammalian acinar cells, comprising culturing the cells in a cell culture system comprising a cell culture medium and a cell attachment surface, under conditions wherein the acinar cells undergo a 3-4 fold expansion together with transdifferentiation into a modified cell phenotype (IP cells) showing characteristics of acinar cells and liver cells. The invention also relates to a method for transforming these IP cells to insulin-producing cells in vitro, comprising culturing the cells in a novel, defined medium. Also disclosed are suitable culture media for performing these methods, isolated cells having the phenotype of IP cells and/or produced by these methods, and kits for performing the methods.

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Description

This application claims the benefit of provisional application 60/384,000, filed May 28, 2002, which disclosure is incorporated by reference in its entirety herein.

BACKGROUND OF THE INVENTION

1. Field of the Invention

The invention relates to compositions and methods whereby, e.g., human pancreatic acinar cells are cultured under conditions that support expansion and transdifferentiation into glandular epithelial cells and subsequently into insulin-producing cells.

2. Background Information

The potential benefits of taking insulin-producing cells from organ donors and transplanting them into insulin-dependent, Type I diabetic patients is clear. In the Edmonton clinical trials, many patients have lived free from the delivery of exogenous insulin for approximately 2 years after being transplanted with intact islets from organ donor sources. However, current technology requires two organ donor pancreata to generate a sufficient number of islets (about 1 million islets, comprised of about 1,000 cells each) to transplant into one diabetic patient for cellular therapy. Thus, there has been emphasis in the diabetes field to identify new sources of insulin-producing cells for transplantation. Many avenues are being explored, including expansion of islets after harvest and before transplantation and the generation of new islets from stem-like cells derived from the bone marrow, or from precursor cells located in the pancreas. The challenges presented by these approaches are related to maintenance of function of islets over long periods of culture, and of the relative rarity of stem-like cells that can be harnessed for insulin production from the bone marrow and pancreas. The ductular precursor stem-like cells derived from the pancreas are reported to be more efficient than bone-marrow derived cells at differentiation into insulin-producing cells, and this may reflect their site of origin (i.e., pancreas) where they are certainly exposed to many differentiation signals related to the pancreatic microenvironment. The most abundant cell type in the pancreas is the acinar cell, which comprises about 85% of the pancreas. The acinar cells serve to produce and secrete digestive enzymes and, like islet cells, arise during development from the ductular cell compartment.

There have been reports that acinar cells, when cultivated in vitro, especially under conditions of stress, can undergo a ‘transdifferentiation’ into a cell type that resembles ductular cells, as determined by expression of CK19, CK7, and carbonic anhydrase (all reputed by the authors to be markers of duct cells) (Kerr-Conte, 1996; WO 02/29010 A2), Hall et al., 1992). Furthermore, Bouwens et al. (1998) have shown in vivo, in a model of pancreatic duct ligation, that acinar cells in the ligated portion of the pancreas undergo transdifferentiation into cells with a ductular phenotype. Further work has suggested that insulin-producing cells can be produced upon further differentiation of the duct cells in the ligated portion of the pancreas. The acinar cells are also reported to be of limited survivability in primary culture, with some culture conditions leading to loss of at least 50% of cells within a week. While primary duct cells have been demonstrated in vitro to convert into insulin-producing cells under some culture conditions (e.g. Bonner Weir, 2000, U.S. Pat. No. 6,011,647), there are no reports of cells that arose from acinar cells in vitro differentiating further to produce islet-like cells.

Prior to the development of the present system, primary pancreatic acinar cells were expanded without differentiation into insulin-producing cells, either in serum-containing medium (undesirable both because of the risk and the uncertainty associated with the use of serum), or in complex serum free media formulations. Likewise, primary pancreatic acinar cells have been transdifferentiated into insulin-producing cells without expansion, producing cells with an insulin-producing phenotype in small numbers. Furthermore, it has not been previously possible to obtain insulin-producing cells in good numbers using acinar cells as starting material.

Thus, there is a need for a simple cell culture system and method for rapidly generating large numbers of cells that can further differentiate into, e.g., insulin-producing cells, through expansion and transdifferentiation of the abundant pancreatic acinar cells. Further, there is a need for a cell culture system and method for culturing and transforming such cells into insulin-producing cells. One cell culture system and related method disclosed herein allows a simple, one-step approach that generates expanded cultures that contain at least 80% intermediate progenitor cells that can give rise to insulin-producing cells. A second cell culture system and related method allows the further culturing of these intermediate progenitor cells or other glandular epithelial cells to obtain insulin-producing cells. Both IP cells and insulin-producing cells will be useful for cell-based therapies for the treatment of diseases such as diabetes.

SUMMARY OF THE INVENTION

The present invention provides compositions and methods whereby, e.g., acinar cells can be cultivated successfully in vitro, undergoing a 3-4 fold increase in cell number over time, and giving rise to a cell population that co-expresses acinar and ductal markers early during the culture (2-3 days ex vivo), then ultimately (e.g., about 7-8 days ex vivo) acquires a modified phenotype characterized by expression of some acinar-associated genes, as well as some liver-associated genes. The genes expressed by these modified cells at about 7-8 days ex vivo include, e.g., ductular cytokeratins (CK7, CK8, CK18 and CK19), hepatic nuclear factor 1 (HNF1), alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific (basic helix-loop-helix (bHLH) transcription factor, Thy-1, CCAAT/enhancer-binding protein (C/EBP)-alpha and C/EBP-beta. These cells exhibit little if any expression of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase. By “little if any” expression of a gene is meant herein that gene expression is generally undetectable under conventional methods, such as the hybridization and immunocytochemical methods described herein, but expression may be detected by extraordinarily sensitive methods, such as PCR-based analysis. This type of modified cell is referred to herein as an intermediate progenitor (“IP”) cell. The expanded/transdifferentiated acinar cells (IP cells) can be produced using a general serum-containing media, or, in a preferred method, can be produced without serum on a surface comprising one or more extracellular matrix molecules (ECMs) in the presence of one or more soluble active factors. ECMs can be presented in 2 dimensional or 3 dimensional culture systems in the presence of soluble active factors.

The IP cells generated from these cultures are expected to be useful directly in certain medical applications. For example, there is evidence that such cells may under certain conditions become functioning insulin-producing cells when implanted in diabetic patients. The cells can also be used for drug discovery and toxicity studies.

In addition, according to a further aspect of the invention, the IP cells can be cultivated further, in a serum-free medium composed of any standard serum-free base medium (DMEM:HamsF12, for example) with BSA and combinations of factors, including ECMs, small molecules, and growth factors. After 5-10 days of culture, the IP cells undergo additional steps of differentiation, culminating in the formation of cell aggregates that express pro-insulin and C-peptide. Challenge of these cultures with a high-glucose medium causes release of insulin and C-peptide into the medium, indicating the production in these cultures of functional islet-like cells.

Thus, in a first aspect, the present invention provides a cell culture system comprising a superior cell attachment surface that also stimulates cellular expansion, and a simple culture medium including effective amounts of one or more soluble active factors, or serum (e.g. fetal bovine serum), added to a base medium composition. The cell culture system will be particularly useful for primary culture of mammalian epithelial cells, particularly human epithelial cells. In a preferred embodiment the cell culture system is used for the expansion and transdifferentiation of primary acinar cells, especially human pancreatic acinar cells.

The cell attachment surface for this cell culture system is any surface to which the cells can attach and expand, including both 2 dimensional (e.g. plates, flasks, roller bottles, petri dishes, wells etc.) and 3 dimensional (e.g. scaffold) environments. Preferably the surface comprises at least one type of ECM, or a peptide fragment thereof. Cells may, in some circumstances, detach from these surfaces and form self-supporting aggregates. Suitable fragments include peptides consisting of a sequence of three of more amino acid residues that are identical to any portion of the amino acid sequence of the ECM. Such fragments can be easily made and tested by means known to those of skill in the art. Most preferably the surface is a layer of collagen I. Many other surfaces known in the art are also suitable, such as Collagen VI, Collagen IV, Vitronectin, or Fibronectin. Collagen I is preferred due to ease and cost.

The base medium to which the soluble active factors are added may be any cell culture medium appropriate for growth and differentiation of epithelial cells. These include, but are not limited to, DMEM, Hams F12, MEM, M-199 and RPMI. The general requirements for such culture media and many suitable examples are known to those of skill in the art. To this base medium is added either serum (such as fetal bovine serum), or a stabilizing protein such as bovine serum albumin (BSA) along with effective amounts of soluble active factors. The medium is preferably serum-free.

Soluble active factors for the expansion and transdifferentiation of primary pancreatic acinar cells into IP cells include growth factors such as HGF receptor activators and EGF receptor activators. Preferred soluble active factors include one or more of EGF and Transforming Growth Factor-α, IGF1, HGF, betacellulin, prolactin and gastrin 1. HGF, EGF and/or Transforming Growth Factor-α are particularly preferred. Also preferred is the combination of IGF1 and betacellulin.

In one particularly preferred embodiment, the base medium contains a 1:1 mixture of DMEM and Hams F12. The base medium is completed with the addition of glutamine to a final concentration of ˜4 mM, insulin (˜0.1-10 μg/ml, preferably ˜0.01 mg/ml), transferrin (˜0.5-10 μg/ml, preferably ˜0.0055 mg/ml), selenium (˜0.25-5.0 ng/ml, preferably ˜0.0067 μg/ml of sodium selenite), and Epidermal Growth Factor (EGF) (˜1-20 ng/ml, preferably ˜10 ng/ml); this medium is hereafter referred to as pancreatic cell medium, or PCM. To this base medium formulation, up to ˜20% Fetal Bovine Serum (or other serum), preferably between ˜10-˜15% fetal bovine serum, most preferably about 10% or up to about 15% fetal bovine serum) may be added, or, to create a serum-free culture environment, the following components are added in place of serum: heat-inactivated bovine serum albumin (0.1-2%), Hepatocyte growth factor (HGF) (1-20 ng/ml), and/or Transforming Growth Factor Alpha (TGFα) (1-10 ng/ml). In addition, the medium may contain Betacellulin (0.5-20 ng/ml), Gastrin 1 (0.05-10 ng/ml), Prolactin (1.0-10 ng/ml), and/or IGF-1 (5-100 ng/ml). In particular formulations, greater or lesser amounts of these components may be added in order to achieve a formulation that is effective in supporting the expansion and transdifferentiation of the cells. Persons of skill in the art will appreciate that determining effective amounts of the components will require no more than routine experimentation.

By the use of this attachment surface and medium, the expansion and transdifferentiation of primary pancreatic cells with the desired phenotype is simplified greatly.

In a particularly preferred embodiment, the cell culture system is a combination of collagen I coated tissue culture surface (presented in a 2 dimensional or 3 dimensional form) and a serum-free medium containing BSA, insulin, transferrin, selenium, Hepatocyte growth factor (HGF), Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGFA).

The cell culture system enables superior attachment in vitro of primary pancreatic epithelial cells for adherent culture compared to prior methods, while creating a cellular environment that promotes expansion of the epithelial component of primary pancreatic cultures with concomitant transdifferentiation of the acinar cells present in the starting material into IP cells, while minimizing emergence of undesired fibroblasts. Advantages of this culture system are ease of construction, few components needed, and that all components are readily available and easily used in the required manner.

The components of this aspect of the invention may be conveniently packaged in the form of a kit. The kit may include, for example, 1) a cell culture medium such as DMEM: 2) a serum-free medium supplement containing BSA, insulin, transferrin, selenium, HGF, EGF and TGFA, in suitable amounts to yield the concentrations noted above in the completed medium; and 3) at least one collagen I coated substrate, such as a vessel for tissue culture (e.g., dish(es) with at least one collagen-1 coated tissue culture surface), or collagen-1 coated inserts for use in culture dishes or other laboratory ware. The kit may also optionally include a tissue culture dish or other cell culture accessories and additional reagents that may be required to carry out epithelial cell culture and differentiation.

Culture systems consisting of scaffolds, collagen coated flasks or other vessels and serum-free base medium may be packaged along with the soluble active factors as a separate vial that would be added to the culture medium just prior to use. The active factor combination can be added to a variety of base media to accomplish the same end, e.g., growth and differentiation of primary pancreatic acinar cells in vitro. Such culture systems should also be useful for other cell types, particularly glandular epithelial cells derived from other organs and tissues, including those from liver, pancreas, intestine, prostate, and breast.

The collagen I surface provides superior cell attachment (thereby increasing the number of cells that adhere during initial culture and thus enhancing culture efficiency), while the collagen I and the combination of soluble active factors (e.g., HGF, TGFA and EGF) promote continued proliferation of cells over time, leading to an increase in cell number above what has been previously reported for primary pancreatic acinar cells. Furthermore, the expansion of the acinar cells is accompanied by a transdifferentiation in the majority of cells to an IP phenotype, which is potentially a therapeutically useful cell phenotype for the treatment of diseases such as diabetes. This likely occurs due to convergence of the intracellular signaling pathways associated with collagen I, HGF, TGFA and EGF, creating a synergistic response.

The cell culture system of the present invention has unexpected advantages over systems previously in use. Collagen I, IV, VI, Vitronectin and Fibronectin were expected to enhance cell attachment. However, other extracellular matrix molecules that yielded equivalent attachment of cells during the initial 18 hours of culture did not promote consistent growth of the cells over time in the serum-free medium containing HGF/EGF/TGFA. The most efficient and cost-effective method of achieving cell expansion AND differentiation into IP cells is to utilize a collagen-I surface and a medium containing reduced serum (preferably less than 20%, more preferably less than 15%, 10%, or 5%, most preferably 2%).

Another aspect of the invention is a method for culturing mammalian epithelial cells comprising adding said cells to the cell culture system described above, and maintaining them at suitable temperature and atmospheric conditions. By “mammalian epithelial cell” is meant any cell of a tissue or organ with an epithelial cell phenotype, defined by the presence of expression of cytokeratins and often through the presence of markers that suggest a tissue-specific function (i.e., epithelial cells of the skin make keratin, epithelial cells of the intestine make mucin, epithelial cells of the prostate make PSA). In a preferred embodiment, the cells are primary pancreatic cells, particularly human pancreatic cells. Suitable temperature for mammalian cells is usually in the range of about 37° C., but may be varied somewhat according to cell type. The atmosphere can be ordinary air, or other specialized mixtures of gasses suitable for maintaining cells, as will be familiar to persons of skill in the art. Expansion of pancreatic acinar cells can be maximized by decreasing the oxygen tension in the culture atmosphere to less than 21%, while transdifferentiation to IP cells can be enhanced by increasing oxygen tension to greater than 5%. A preferred range of oxygen tension is between about 5% and about 21%.

In a second aspect, the invention also provides methods and compositions for transforming glandular epithelial cells that have acquired expression of markers characteristic of an intermediate progenitor (IP) phenotype as described above into insulin-producing cells. By “glandular epithelial cell” is meant an epithelial cell that is a component of a gland. Glands are tissues that have a specific function related to secretion of key molecules—most organs in the body have glandular function (liver, intestine, pancreas, prostate, breast, pituitary, adrenal, kidney) whereby they produce and release hormones, digestive enzymes, or other life-essential fluids. Glandular epithelial cells from endoderm-derived organs (e.g., liver, intestine, pancreas) share many characteristics, including the ability to express many of the same genes. Particularly preferred are glandular epithelial cells from pancreas, for example acinar cells. As used herein, the terms “express” and “expression” generally refer to nucleic acids (e.g., mRNAs) or to protein gene products that are detectable by standard immunocytochemical methods.

In this aspect, the invention provides a second cell culture system comprising a cell attachment surface and a culture medium that supports and promotes the transformation of glandular epithelial cells into insulin-producing cells. The cell attachment surface is similar to and may be identical to the attachment surface for expanding primary pancreatic acinar cells. It may be presented in the form of a flat surface coated on a vessel or in the form of a scaffold or other surface adapted for cell culture. It can be comprised of, or coated with, any composition that is capable of maintaining cells or supporting cell growth. In a preferred embodiment, it comprises at least one ECM, such as Collagen I, Collagen VI, Collagen IV, Vitronectin or Fibronectin. In a particularly preferred embodiment, the cell attachment surface is Collagen-I.

In this aspect, the invention provides a further culture medium comprising at least one differentiation promoting factor (“DPF”) that promotes the transformation of glandular epithelial cells into insulin producing cells. The DPFs for the transformation of glandular epithelial cells into insulin producing cells can be one or more of Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), or VEGF. Preferred concentrations in culture medium of each of these 23 DPFs are listed in Table 1. Although in some cases one DPF is sufficient, preferably two or more factors are used. As many as all 23 of the factors may be used.

TABLE 1 Concentration (micrograms/ Substance mL) Activin A (human, recombinant) 0.0005 CGRP alpha, (Calcitonin Gene Related Peptide, rat) 0.1905 C natriuretic peptide) (human, porcine, rat: frag 32-53) 0.10985 (CNP) Cholera Toxin B Subunit, recombinant 0.0125 DEXamethasone (9 alpha-fluoro-16alpha- 0.002 methylprednisolone)(hydrocortisone analogue) FGF acidic (aFGF = FGF1), Recombinant Human 0.0025 GLP-1 (7-36) amide, human (Glucagon-Like Peptide 0.033 1) Glucose (base should be l0ow; 0.9 ug/ml) 1.08 Insulin, human (low [ ] in base media 1 ug/ml) 9.5 LIF, human (leukemia inhibitory factor, human) 0.0025 PDGF AA + PDGF BB MIX 0.005 TGF alpha 0.001 Prolactin (human, recombinant)(a plasma growth 0.0012 hormone) Trolox (soluable Vitamin E) (C14H18O4) 0.625 GRP (Gastrin Releasing Peptide, Human) 0.143 IGF-1, recombinant human 0.0025 IGF-2, recombinant human 0.0025 Laminin 2.25 Met-Enkephalin (tyr-gly-glyl-phe-met) 0.003 Sonic Hedgehog (mouse, recombinant) 0.025 Substance P (full length) (H1875 is frag 1-4) 5 FGFb (=FGF2), human Recombinant 0.0025 VEGF 0.0025

In a preferred embodiment of this aspect of the invention, the culture medium comprises at least one (or as many as all 10) of the following differentiation promoting DPFs:.C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Laminin, Met-Enkephalin, PDGFAA+PDGFBB, Sonic Hedgehog, and Substance P.

In a preferred embodiment, the culture medium that promotes the transformation of glandular epithelial cells into insulin producing cells consists of a 1:1 mixture of DMEM and Hams F12 plus the components listed in Table 2. This medium is sometimes referred to herein as “Media or Medium G9.”

TABLE 2 Factor Substance Concentration (Final) ug/ml 1 ANP Atrial Natriuretic 0.1530 Peptide, Rat (28 amino acids) 2 CCK-8-frag-amide CCK8, Fragment 26-33 0.0250 Amide (Cholecystokinin) (Asp-Tyr(SO3H)-Met- Gly-Trp-Met-Asp-Phe- NH2) 3 Caerulin sulfate Caerulein (Pyr-Gln- 0.0300 Asp-Tyr(SO3H)-Thr- Gly-Trp-Met-Asp-Phe- NH2 4 Cholera Toxin-B Cholera Toxin B 0.0125 Subunit, recombinant 5 Dex DEXamethasone (9 0.0020 alpha-fluoro-16alpha- methylprednisolone)(hydrocortisone analogue) 6 FGF-7 FGF7 (KGF) 0.0025 7 GLP-1 GLP-1 (7-36) amide, 0.0330 human (Glucagon-Like Peptide 1) 8 GRP GRP (Gastrin 0.1430 Releasing Peptide, Human) 9 Gastrin-1 Gastrin I Human 0.0000 10 Glucose Glucose (base should 1.0800 be l0ow; 0.9 ug/ml) 11 HGF Hepatocyte Growth 0.0025 Factor (HGF) recombinant 12 IGF-1 IGF-1, recombinant 0.0025 human 13 IGF-2 IGF-2, recombinant 0.0025 human 14 Insulin Insulin (low [ ] in base 9.5000 media 1 ug/ml) 15 Leu-Enkephalin Leu-Enkepthalin (tyr- 0.0030 gly-gly-phe-leu) 16 Nicotinamide Nicotinamide 610.0000 17 PTHRP-frag-1-34 pT II RP (Parathyroid 0.2060 Hormone Related Peptide (1-34), human) 18 Progesterone Progesterone 0.0030 19 Prolactin Prolactin (human, 0.0012 recombinant)(a plasma growth hormone) 20 Retinol acetate Retinoic Acid (Vitamin 0.0250 A) 21 SHH Sonic Hedgehog 0.0250 (mouse, recombinant) 22 Sodium selenite Selenium (Selenous 0.0250 Acid, Na salt) 23 Soybean trypsin inhibitor Trypsin Inhibitor, 0.5000 soybean (type I-S) 24 TGF-beta sRII TGF beta sRII (soluable 0.0050 receptor type 2) 25 Transferrin transferrin 2.7500 26 Trolox Trolox (soluable 0.6250 Vitamin E) (C14H18O4) 27 VIP Vasoactive Intestinal 0.0665 Peptide (VIP), human 28 aFGF FGF acidic (aFGF = FGF1), 0.0025 Recombinant Human 29 bFGF FGFb (=FGF2), human 0.0025 Recombinant 30 n-Butyric acid n Butyric Acid, Sodium 4.5400 Salt

The components of this aspect of the invention may also be conveniently packaged in the form of a kit. The kit may include, for example, 1) a cell culture medium such as DMEM, Hams F12, or a combination thereof, 2) a serum-free medium supplement containing: BSA and the DPFs Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), or VEGF, or two or more of these components in combination, in suitable amounts to yield the concentrations noted in Table 1 in the completed medium; and 3) tissue culture dish(es) with at least one collagen-1 coated tissue culture surface (or collagen-1 coated inserts for use in culture dishes or other laboratory ware). The kit may also optionally include a tissue culture dish and/or other cell culture accessories and additional reagents that may be required to carry out epithelial cell culture and differentiation. In other embodiments, the kit may contain any of the media or media components discussed herein.

Culture systems consisting of scaffolds, collagen coated flasks or other vessels and serum-free base medium may be packaged along with the DPF(s) as a separate vial that would be added to the culture medium just prior to use. The DPF combination can be added to a variety of base media to accomplish the same end, e.g., growth and differentiation of primary pancreatic acinar cells in vitro. Such culture systems may also be useful for other cell types, particularly other epithelial cells derived from glandular tissues, including those from liver, pancreas, intestine, prostate, and breast.

The invention also provides a method for converting glandular epithelial cells into insulin-producing cells comprising culturing the glandular epithelial cells in the cell culture system described above. The method may further comprise removing the culture medium from the cell culture, re-feeding the cell culture with a serum-free medium with glucose, and measuring proinsulin production C-peptide production, or insulin release.

Furthermore, the invention provides an isolated population of insulin-producing cells containing cytoplasmic granules with immunodetectable proinsulin, insulin, and/or c-peptide that is derived from a population of cells of which a subset of cells expressed at least one marker associated with IP cells (e.g., expressed some acinar-associated genes, as well as some liver-associated genes, including, e.g., ductular cytokeratins (CK7, CK8, CK18 and CK19), HNF1, alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific bHLH transcription factor, Thy-1, C/EBP-alpha and C/EBP-beta, and expressed little if any of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase).

By an “isolated” cell or population of cells is meant herein that the cell or cell population is removed from its original environment (e.g., the natural environment if it is naturally occurring), and isolated or separated from at least one other component with which it is naturally associated. For example, a naturally-occurring cell present in its natural living host is not isolated, but the same cell, separated from some or all of the coexisting materials in the natural system, is isolated. Such cell or cell populations could be part of a cell culture or cell population, and still be isolated in that such culture or population is not part of its natural environment.

In one preferred embodiment, the insulin-producing cells are derived from glandular epithelial cells obtained from mammalian pancreas, such as primary acinar cells.

The data disclosed in the examples below are generated from freshly isolated human pancreatic cells. The expansion of primary human pancreatic cells in these conditions produces cultures with a mixed epithelial IP phenotype, suitable for in vitro studies of IP cells for a variety of purposes, and suitable for transplantation in vivo for cell therapy for the treatment of diseases such as diabetes. The IP cells generated by these methods may also be useful in the study of pancreatic cell biology, as normal controls in the study of pancreatic epithelial cancers, and to test the effects of drugs/compounds on normal pancreatic epithelial cells (ductal or acinar). Furthermore, the cells may be further cultured to yield insulin-producing cells as demonstrated below.

BRIEF DESCRIPTION OF THE DRAWINGS

FIGS. 1A-D show microscopic images after treatment of starting material with antibodies to amylase (FIG. 1A), insulin (FIG. 1B), and CK19 (FIG. 1C) and the composition of the cell pellet of freshly isolated primary human pancreatic cells (FIG. 1D).

FIG. 2 shows growth curves constructed from primary human pancreatic cultures grown in commercial medium (with serum) or in the described pancreatic cell medium (PCM) with serum.

FIG. 3 shows a comparison of cell expansion in the base medium composition described vs. base medium+soluble growth factors (serum-free formula) vs. base medium+fetal bovine serum.

FIGS. 4A-B shows the effect of different culture surfaces on total cell number (FIG. 4A) and cell phenotype (FIG. 4B) after expansion.

FIGS. 5A-B show a comparison of cell phenotype after expansion in serum-containing (5A) and serum-free (5B) medium containing all soluble active factors.

FIG. 6 shows high power images of cell cultures expanded in various conditions, including serum-free base media supplemented with 3 soluble active factors, HGF, EGF & TGFA. Note epithelial morphology.

FIG. 7 shows a demonstration of growth of IP cells on ECM-coated surfaces as determined by metabolic activity assay over time. Note superior growth when Collagen I surface is combined with the media formulation described herein, yielding results superior to the combination of Matrigel and commercial media with serum.

FIG. 8A (upper left) shows expression of amylase by acinar cells after two days of culture (red staining), FIG. 8B (lower left) shows expression of CK19 (green staining), FIG. 8C (right) shows an overlay of the two images, showing co-expression (yellow) in a large proportion of cells.

FIG. 9 shows changing phenotype of primary acinar cells in culture over 5 days. Amylase is red, CK19 is green. Note appearance of yellow (amylase+CK19) on Day 2 and 3.

FIGS. 10A and 10B show primary human pancreatic cells that were expanded in serum-containing medium on Collagen I coated surface. Images were analyzed to determine total cells (FIG. 10A, blue nuclei) and total positive cells (FIG. 10B, blue nuclei surrounded by green staining for CK19).

FIG. 11 shows light microscopic (200×) appearance of pancreatic acinar cells cultured on a collagen I surface with all DPFs (Activin A, 0.5 ng/ml; acidic FGF, 2.5 ng/ml; basic FGF, C-Natriuretic Peptide (CNP), 0.11 μg/ml; Calcitonin Gene Related Peptide, 0.19 μg/ml; Cholera Toxin B Subunit, 12.5 ng/ml; Dexamethasone, 0.002 μg/ml; Gastrin-Releasing Peptide, 0.143 μg/ml; Glucagon-like Peptide-1 (GLP-1), 0.033 μg/ml; Glucose, 1.08 μg/ml; IGF1, 0.0025 μg/ml; IGF2, 0.0025 μg/ml; Insulin, 9.5 μg/ml; Laminin, 2.25 μg/ml; LIF, 0.0025 μg/ml; Met-Enkephalin, 0.0030 μg/ml; PDGFAA+PDGFBB (0.0050 μg/ml: 0.0025 μg/ml of PDGFAA+0.0025 μg/ml PDGFBB); Prolactin, 0.0012 μg/ml; Sonic Hedgehog, 0.025 μg/ml; Substance P, 5.0 μg/ml; TGF-alpha, 0.0010 μg/ml; Trolox (alpha-tocopherol derivative), 0.625 μg/ml; and VEGF, 0.0025 μg/ml).

FIG. 12A (top right panel) shows immunocytochemical analysis with CK19 antibodies (green).

FIG. 12B (lower right panel) shows immunocytochemical analysis with C-peptide antibodies (red).

FIG. 12C (left panel) shows an overlay image demonstrating the colocalization of CK19 and C-peptide (orange). Blue portions are DAPI stained nuclei.

FIG. 13A shows insulin release upon glucose challenge in IP cells that have not been detached and relocated (subcultured) during the growth and differentiation process.

FIG. 13B shows insulin release upon glucose challenge in IP cells that have been subcultured according to Example 10.

FIG. 13C shows C-peptide release upon glucose challenge in IP cells that have not been subcultured according to Example 10.

FIG. 14 shows the Insulin/DNA ratio in subcultured and nonsubcultured cells that are treated with Combinations 1, 2 and 3 of DFP media, as described in Example 11.

FIG. 15 shows insulin release in response to base level glucose (5 mm) and a glucose challenge (22 mm) over 10 days of culture in PCM and DPF media, as described in Example 13.

FIG. 15A shows insulin release in response to base level glucose (5 mm) and a glucose challenge (22 mm) over 14 days of culture in PCM and DMG9 media, as detailed in Example 14.

FIG. 16 is a graphical representation of the characteristics of the 17 classes of genes shown in Table 6, as indicated in the last column of the Table, as detailed in Example 14.

DETAILED DESCRIPTION OF THE INVENTION

In describing preferred embodiments of the present invention, specific terminology is employed for the sake of clarity. However, the invention is not intended to be limited to the specific terminology so selected. It is to be understood that each specific element includes all technical equivalents, which operate in a similar manner to accomplish a similar purpose. Each reference cited here is incorporated by reference as if each were individually incorporated by reference.

The following abbreviations are used:

BSA: bovine serum albumin

BMP Bone Morphogenetic Protein

bHLH: basic helix loop helix

DMEM: Dulbecco's Modified Eagle's Medium

TGFβ1: Transforming Growth Factor β1

ECM: extracellular matrix molecules; naturally occurring proteins produced by cells of a tissue that provide structural support as well as a source of cellular signals related to adhesion. Examples are collagen, vitronectin, fibronectin, laminin.

EGF: Epidermal Growth Factor

Hams F12: Ham's Nutrient Mixture F12

HGF: Hepatocyte growth factor

HNF-1: Hepatic nuclear factor 1

IGF1: Insulin-like growth factor 1

IGF-II: Insulin-like growth factor 2

IP cells: Intermediate progenitor cells derived from an epithelial cell, such as, e.g., a pancreatic acinar cell or a liver cell, wherein the derived cells express some acinar-associated genes, as well as some liver-associated genes, including, e.g., cytokeratins (CK7, CK8, CK18 and CK19), HNF1, alpha-1 antitrypsin, pi-glutathione s transferase (pi-GST), liver-specific bHLH transcription factor, Thy-1, C/EBP-alpha and C/EBP-beta, and express little if any of the pancreas-associated genes carbonic anhydrase, cystic fibrosis transmembrane conductance regulator (CFTR), elastase and amylase).

PDGF-A: Platelet derived growth factor alpha

PDGF-B: Platelet derived growth factor beta

TGFA, TGF-α Transforming Growth Factor α

As used herein, the term “culture system” is intended to mean a system for growing and/or differentiating cells in culture, which comprises a cell attachment surface, preferably one that also stimulates cellular expansion, and a culture medium, which includes effective amounts of one or more factors, or serum (e.g. fetal bovine serum), added to a base medium composition.

When referring to active soluble factors and DPFs herein, “effective amount” means an amount that either alone or in combination with other included factors is effective in promoting either expansion and differentiation into IP cells, or into insulin-producing cells, as applicable.

EXAMPLES

I. Expansion and Transdifferentiation of Primary Acinar Cells into Glandular Epithelial Cells (Culture Phase I)

Materials and Methods:

Starting Material: Primary human pancreatic acinar cells are collected as waste from standard COBE gradient preparation of islet cells for transplantation (Lake et al., 1989). After density gradient centrifugation, the islets are present as a layer between 1.063 density and 1.10 density, and the remaining cells are collected as the pellet that sediments to the bottom of the gradient based on density. Approximately 48 hours after collection of the cells at the transplant center are received by the inventors in non-tissue-culture treated polystyrene flasks and are suspended in RPMI+10% fetal calf serum at a density of approximately 2.0 million cells/ml. Cell number and viability is assessed by trypan blue exclusion and enumeration on a hemacytometer by light microscopic observation.

Phenotypic Evaluation of Starting Material. A preparation of starting material was formalin fixed and paraffin-embedded as a cell pellet about 24 hours after initial harvest of the pancreatic cells. Paraffin sections were prepared, placed on slides, and subjected to immunocytochemical analysis with antibodies to insulin (Biogenex, San Ramon, Calif.), CK19 (Biogenex), and Amylase (Biogenex). A minimum of (3) sections per sample were assessed with each marker. All antibody staining was carried out according to the manufacturer's suggestion with pre-diluted commercial antibodies. For CK19, a 3 minute treatment with pepsin enzyme (Biogenex) preceded the blocking step for the purpose of antigen retrieval. Briefly, the sections were rehydrated through graded ethanols, followed by a 15 minute incubation in phosphate buffered saline (PBS) without calcium and magnesium. Protein Blocker (Biogenex) was added for 30 minutes prior to addition of primary antibodies. After (3) 5-minute washes, biotinylated secondary antibody (Biogenex) was added at a 1:100 dilution and sections were incubated for 30 minutes at room temperature. After (3) 5-minute washes, Alexa488 or Alexa-596-conjugated StreptAvidin (Molecular Probes, Eugene, Oreg.) was added for fluorescent visualization. For each slide, a minimum of (3) 200× images were captured using a Nikon fluorescent microscope fitted with a SPOT camera (Diagnostic Systems, Inc., Webster, Tex.). The images were assessed quantitatively using image analysis software (MetaMorph/Universal Imaging Corporation, Downington, Pa.) to determine relative fraction of insulin-positive, CK19+, and amylase+ cells. Insulin+ cells are the beta cells of the islets, CK19+ cells are the primary ductal cells, and amylase+ cells are the acinar cells (see Example 1).

Example 1 Characterization of Cell Culture Conditions

A. Serum-Free Medium

Freshly isolated primary human pancreatic cells were collected as a pellet from a COBE cell separator, fixed in formalin, paraffin-embedded, sectioned, and analyzed with antibodies to amylase, CK19, and Insulin. Images (FIGS. 1A and 1B) were collected on a Universal Imaging System (Universal Imaging Corporation) and analyzed with MetaMorph Software. This cell pellet (FIG. 1C) was comprised of 1.0% insulin+ cells (beta cells of the islet), 5.8% CK19+ cells (primary ductal cells), and 93.2% amylase+ and unlabeled (acinar cells and other cell types).

Primary human pancreatic cells were then seeded at 104 or 105 cells/cm2 onto tissue culture treated polystyrene in either DMEM commercial medium plus 10% fetal bovine serum or in PCM plus 10% fetal bovine serum. Replicate cultures were harvested at 3 day intervals via trypsinization and live cells (as determined by trypan blue exclusion) and enumerated on a hemocytometer. The results (shown in FIG. 2) demonstrate that the (serum-containing) medium formulation described herein is superior to commercial media formulation for growth and maintenance of primary pancreatic cells. FIG. 3 compares the results of expanding the cells for 6 days in base medium, base medium plus all of the soluble active factors [HGF, ˜1-˜20 ng/ml, preferably ˜5.0 ng/ml; TGFA, ˜1-˜10 ng/ml, preferably ˜2 ng/ml; Betacellulin, ˜0.5-˜20 ng/ml, preferably ˜10 ng/ml; Gastrin 1, ˜0.05-˜10 ng/ml, preferably ˜0.06 ng/ml; Prolactin, ˜1.0-˜10 ng/ml, preferably ˜2.4 ng/ml; and IGF1, ˜5-˜100 ng/ml, preferably ˜5 ng/ml] and base medium plus 10% serum. The serum-free media formulation meets/exceeds expansion provided by media+serum.

The cell expansion experiment was repeated essentially as above, except that the base medium was supplemented with only three of the soluble active factors: TGF, HGF, and EGF. FIG. 6D compares the results of expanding the cells in the various media; FIGS. 6A, 6B and 6C show high power images of the cell cultures expanded under the various media conditions.

B. ECM Surfaces

The attachment of primary human pancreatic cells was evaluated by counting the number of attached cells vs. the number of cells initially seeded on a panel of ECM surfaces comprised of Collagen I (1 μg/cm2), Fibronectin (3 μg/cm2), Laminin (2 μg/cm2), Vitronectin (1 μg/cm2), Matrigel (1 μg/cm2), Human ECM (1 μg/cm2), or Poly-D-Lysine (3 μg/cm2). In one condition, a mixture of Collagen IV, Laminin, and Fibronectin was utilized. ECMs were placed into solution at the above concentrations and allowed to coat tissue culture-treated polystyrene surfaces according to manufacturer's suggestions of 1 hour at room temp. Excess ECM solution was then removed and surfaces were rinsed twice in water. Just before seeding cells, the water was aspirated, then cells were seeded onto the ECM surface at a density of 1×105 cells/cm2 in growth medium (PCM) composed of DMEM:HamsF12 mixture (1:1) with 4 mM glutamine, 1×ITS supplement (GIBCO 51500-056), 10% Fetal Calf Serum (Inactivated, Qualified, GIBC 26140-079), and 10 ng/ml Epidermal Growth Factor (EGF) (BD 4001). Cells were seeded onto tissue-culture polystyrene surface as a control. After 18 hours, unattached cells were washed away and remaining attached cells were re-fed with PCM and allowed to grow for 7 days prior to evaluation. Cultures were fixed in 10% formalin and subjected to immunocytochemistry with antibodies for CK19 and Amylase as described previously to determine phenotypic composition. Cells were counterstained with DAPI fluorescent blue nuclear stain to visualize individual cell nuclei for cell counting. The metabolic activity of cells subjected to the various conditions was determined by an MTS assay. Viable cells were measured using the MTS assay (Promega CellTiter 96 Aqueous One Solution Cell Proliferation Assay), a colorimetric method for determining the number of viable cells in proliferation or cytotoxicity. The results of this analysis are shown in FIG. 7.

Example 2 Further Studies with ECM Surfaces and Various Media Components

Primary pancreatic cells, composed of >90% non-islet/non-duct cells, were plated onto various coated surfaces at a density of 28,900 cells/well (105 cells/cm2). Unattached cells were washed off after 18 hours, and cultures were re-fed and allowed to grow for 8 days. Cultures were fixed in formalin (10%) and subjected to phenotypic analysis with antibodies to CK19 and Amylase. The results are shown in FIG. 4A-B. While Collagens I, IV, Laminin, Fibronectin, and Matrigel provide a suitable surface for cell attachment and expansion, maintenance of acinar (amylase+) phenotype along with the presence of an increased proportion of cells with a glandular epithelial phenotype (CK19+) was superior on Collagen I. More than 50% of cells analyzed expressed amylase and more than 50% of cells analyzed expressed CK19, suggesting that a subpopulation of cells in these experimental conditions express both markers.

Tissue culture-treated polystyrene culture surfaces were coated with Collagen I as described above. Tissue culture medium (PCM) was prepared as described above. In some cases, serum was replaced with Fraction V BSA (99% pure, heat inactivated, Sigma), along with combinations of soluble growth factors, including IGF1, IGF2, betacellulin, HGF, EGF, and TGF-alpha. Optimal seeding density is between 104 and 105 cells/cm2, as demonstrated in Example 3. Cells were seeded onto collagen-coated flasks (150 cm2) at 1.5×106 cells/flask in PCM. After an ˜18 hr attachment period, unattached cells were washed away with gentle aspiration/rinse, followed by re-feeding with fresh medium. Cultures were monitored over time by metabolic assay (MTT) and by trypsinization and cell counting, to establish cell number (see example 3). Cell phenotype at the end of the culture period was assessed as follows: small-scale cultures were set up simultaneously in 96-well plates. At the end of the culture phase, monolayer cells were fixed in 10% formalin for a minimum of 1 hour. After formalin was removed and monolayers were rinsed, cultures were subjected to immunocytochemistry as described in previous section for CK19, amylase, insulin, and vimentin (a marker of fibroblasts). The relative fraction of CK19+ cells was determined by quantitative image analysis as described above (see Example 4). After formalin was removed and monolayers were rinsed, cultures were subjected to immunocytochemistry as described in previous section for CK19 and vimentin (a marker of fibroblasts). Cells were also stained with amylase antibodies, but did not produce positive results due to release of digestive enzymes, such as amylase, by the cells over time in culture. The relative fraction of CK19+ cells was determined by quantitative image analysis as described above (see example 4). Acquisition of ductal markers by acinar cells was verified by demonstrating concomitant expression of CK19 and amylase in cell subpopulations during days 2-3 of culture (see example 5). For these experiments, CK19 primary antibodies were reacted with formalin-fixed cell cultures, followed by visualization with Alexa488-conjugated Goat anti-mouse IgG (Molecular Probes). Then, cells were subjected to a blocking step (Protein Blocker, BioGenex), followed by application of the second primary antibody (anti-amylase). Visualization of the amylase was accomplished by application of Alexa594-conjugated Goat Anti-Mouse IgG. Images were collected as described above. At the end of a 7-day culture period in the conditions described herein, between 65-90% of the cells in the culture express CK19, while less than 20% express vimentin (see example 6). Variations in the relative proportion of CK19+ cells probably reflect heterogeneity due to age, gender, and other unique characteristics of individual patients.

Example 3 Density of Cell Seeding

Primary pancreatic cells were seeded at (3) densities on tissue-culture treated polystyrene dishes (60 mm) and fed with PCM. Light microcopic observations were made daily. At the 24-hour timepoint, dishes were sacrificed and stained with trypan blue to assess viability. The results are shown in Table 3.

TABLE 3 After 3 days Seeding Density At 24 Hours: At 48 Hours: Growth: 104 cells/cm2 Most cells attached, Mitotic Figures present Epithelial trypan blue negative (light microscopy) monolayer (live) forming 105 cells/cm2 Most cells attached, Mitotic Figures present Epithelial trypan blue negative (light microscopy) monolayer (live) forming 106 cells/cm2 Some cells attached, Few Mitotic Figures Cells are most are trypan blue positive present (light microscopy) detached; some (dead) fibroblasts present

Example 4

Cells were grown on a Collagen I surface, at 37° C. in 21% oxygen, in PCM medium or in base medium with 2% BSA, 2 ng/ml TGF-α, 10 ng/ml EGF, and 10 ng/ml HGF. After 7 days, cultures were fixed in 10% formalin and subjected to immunocytochemical analysis with fluorescent detection, followed by automated image collection and analysis. The results are shown in FIGS. 5A and 5B. Fibroblast (vimentin+) fraction, glandular epithelial cell fraction (CK19+), and fraction of unlabeled cells (Other) are similar after expansion. This suggests that replacement of serum with the serum-free medium maintains fraction of CK19+ cells without overgrowth of fibroblasts as compared to cells grown in serum-containing media.

Example 5

Primary pancreatic acinar cells were cultured for several days in a 1:1 ratio of DMEM and HamsF12, with 10% fetal bovine serum, 0.01 mg/ml insulin, 0.0055 mg/ml transferrin, 0.0067 μg/ml sodium selenite, 10 ng/ml EGF, 4 mmol/liter glutamine and antibiotics. After 2 days of culture (4 days ex vivo), expression of amylase by the acinar cells is still strong (FIG. 8A, upper left panel, red staining) as determined by immunocytochemistry. Expression of CK19 is also apparent (FIG. 8B, lower left panel, green staining). Overlay of the two images (FIG. 8C) demonstrates clear co-expression of amylase and CK19 in a large proportion of the cells, indicating that an intermediate cell exists from active conversion of amylase+ acinar cells to an amylase+/CK19+ mixed acinar/ductal phenotype (AD cells). Daily evaluation of cultures (FIG. 9) demonstrated that onset of CK19 expression begins around Day 2 of culture and by Day 5 cultures have lost most immunodetectable amylase expression and CK19 expression is prevalent.

Example 6

After 7 days of growth in PCM/Collagen I surface, cells were fixed, stained with antibodies to CK19, and counterstained with nuclear DAPI. Total cell number was evaluated by automated image analysis (FIG. 10A left panel, blue-stained cell nuclei), while CK19+ cells were counted (FIG. 10B, right panel, green-stained cell cytoplasm). Of 378 total cells, 342 were immunopositive for CK19 (90%). After approximately 7 days of culture using conditions described herein, the acinar cells have concrete ductular characteristics, now referred to as IP cells. For most primary human cultures, more than 80% of cells in the culture after about 7 days express markers such as CK19 that are associated with ductular cells from a variety of tissues.

Example 7 Gene Expression Analysis of 7-Day Cultures (IP Cells)

Two independent IP cell cultures were subjected to Clontech 8K Atlas Gene Array analysis. IP cells were obtained by culturing primary acinar cells in a cell culture system comprising PCM and a Collagen I surface. Monolayer cultures were rinsed 2× with PBS, then detached from the flasks with 0.25% trypsin. Cells were pelleted by centrifugation at 1,200 RPM for 3 minutes in a swinging bucket centrifuge. Cell pellets were resuspended and washed 2× in PBS before a final centrifugation at 1,200 RPM for 3 minutes as described above. The supernatant was discarded and gently aspirated to remove as much liquid as possible from the cell pellet, which was then quick-frozen in a dry-ice/ethanol bath and stored at −80° C. until transfer to BD Clontech where gene expression analysis was performed, using conventional techniques.

Labelled P-33 cDNA probes were prepared from the 30 μg of total RNA from each sample by first enriching for poly A+RNA using a streptavidin-magnetic bead separation method that is part of the Atlas Pure Total RNA Labeling system. The labeled probes from each sample were hybridized with the plastic human 8 K gene arrays for about 16 hours, the arrays were washed and imaged according to the Atlas array protocols. The Atlas image 2.7 software was used to align array images with the array grid template and to exclude false background signals or false signals due to strong signal bleedover. The transcript signals were then extracted from these aligned arrays using the Atlas Image 2.7 software and further statistical analysis of the changes in gene expression were performed.

In general, mRNA transcription was assayed, by hybridization to suitable oligonucleotide probes. In a few cases, e.g., for CK19 and amylase, the protein expression product was measured, using conventional methods of immunohistochemistry. A summary of the expression by these cell populations of a selected set of genes is presented in Table 4. Table 4 contains a list of genes expressed in IP cells and a comparison of expression patterns in primary acinar cells and primary ductal cells. Gene products identified as “+” were expressed; those identified as “++” were strongly expressed. Gene products designated) are found in regenerating pancreas.

TABLE 4 Primary Acinar Gene IP Cells Primary Ductal Cells Cells Aquaporin 1 + ++(mRNA)/+(protein) 0 Aquaporin 5 ++ +(mRNA)/−(protein) Aquaporin 8 + − + Insulin Receptor Substrate-2 + ++ ® Protein Kinase B (AKT) 0 + + Calpain (mu) ++ − ++ CFTR (Cystic Fibrosis 0 0 0 Transmembrane Conductance Regulator) Claudin 2 nd ++ − Claudin 3 + + + Claudin 4 + + + Claudin 5 nd − ++ Carbonic Anhydrase II 0 0 0 Inositol 1,4,5 triphosphate ++ − ++ Rc, Type 3 MUC-1 + ++ + MUC-6 ++ + Cytokeratin 7 ++ ++ − Cytokeratin 8 ++ + Cytokeratin 18 + + Cytokeratin 19 + ++ − alpha v integrin 0 + alpha 3 integrin ++ n/a beta 3 integrin 0 + beta 4 integrin + n/a beta 5 integrin 0 + fibronectin 0 + collagen IV + + vitronectin 0 + ® MMP2 0 Trace MMP9 + Trace TIMP1 ++ Trace TGF-alpha Trace ++ ® Gastrin 0 ++ ® ICAM-1 0 0 ICAM-2 0 0 ICAM-3 0 0 Pancreatitis Associated ++ + ® Trace Protein (PAP) Reg-1 + 0 Trace pyrimidinergic receptor P2Y + + Syndecan + +(low) Trace Glutathione S Transferase - + + − pi

II. Transformation of Glandular Epithelial Cells into Insulin Producing Cells—Generating Insulin-Producing Cells by Differentiation of IP Cultures (Culture Phase II)

IP cultures can be utilized to generate insulin-producing cells by placing the cells in a second phase of culture that includes a surface, such as Collagen I, that promotes attachment of the IP cells combined with a defined medium formula that lacks serum but contains combinations of the following differentiation promoting factors: Activin A, acidic FGF, basic FGF, C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Glucagon-like Peptide-1 (GLP-1), Glucose, IGF1, IGF2, Insulin, Laminin, LIF, Met-Enkephalin, PDGFAA+PDGFBB, Prolactin, Sonic Hedgehog, Substance P, TGF-alpha, Trolox (alpha-tocopherol derivative), and VEGF. In the following examples, the base medium is composed of a 1:1 mixture of HamsF12 and DMEM with antibiotics and 0.2% Bovine Serum Albumin (Fraction V, heat inactivated 99% pure). In one example (Combination 1), the base medium contained Cholera Toxin B, Dexamethasone, GRP, GLP-1, Glucose, IGF-1, IGF-2, Insulin, Prolactin, Sonic Hedgehog, Trolox, aFGF, and bFGF. In another example (Combination 2), the base medium contained Activin A, CGRP-alpha, CNP, Glucose, GLP-1, IGF-2, Insulin, LIF, Met-Enkephalin, Prolactin, Sonic Hedgehog, aFGF, and vEGF. In a third example (Combination 3), the base medium contains Activin A, CGRP-alpha, Cholera Toxin B, Dexamethasone, Glucose, GLP-1, Insulin, LIF, Laminin, Met-Enkephalin, PDGFAA/BB, Sonic Hedgehog, Substance P, TGF-alpha, aFGF, and VEGF. The concentrations of these media supplements are listed in Table 1.

AD cells were placed into culture by either: 1) trypsinizing the cells from the surface on which they were generated, and redistribution onto a fresh attachment-promoting surface at a density of ˜5×104 cells/cm2, or 2) removing the medium, washing 2× in PBS to remove traces of old medium, and cultures re-fed with the new medium (described above) containing differentiation promoting factors. Cells are cultured for a period of 4-10 days at 37° C. and 21% oxygen. On Day 5, half of the medium is removed and replaced with an equal volume of fresh medium containing differentiation promoting factors.

Phenotypic Analysis of IP cells After Differentiation Culture.

Morphological assessment of IP cells cultured in differentiation conditions described above was captured by light microscopy (see Example 8, below). The cellular phenotype of the cells comprising these cultures was assessed by immunocytochemistry as described above using monoclonal antibodies to vimentin, pro-insulin, C-peptide, MUC-1, and CK19 (See Example 10, below). Briefly, cultures were fixed with 10% formalin for 1 hour at room temperature, then washed with PBS and subjected to immunocytochemical protocol. (See Example 9, below).

Functional Analysis of IP cells After Differentiation Culture.

The ability of the aggregated cell clusters to release insulin and C-peptide was assessed by subjecting the cultured cells to a glucose challenge as follows. Cells that had been cultured in differentiation medium for 7-10 days were washed 3× in PBS, then re-fed with either 1) base medium (described above) with 5 mM Glucose, or 2) base medium with 22 mM glucose. After 18 hours, the cell-conditioned medium was collected and subjected to ELISA analysis for insulin and C-peptide release (Diagnostic Systems Laboratories (DSL)). ELISAs were conducted using the standard range assay procedure according to manufacturer's specifications. Plates were incubated on a shaker during the assay and results were read in a Tecan spectrophotometric plate reader. Total ng of insulin or C-peptide per well were calculated for each media condition, for both 5 mM glucose media and 22 mM glucose media (See Example 10).

Example 8

Pancreatic acinar cells were cultured in Base Medium+ITS+Serum (10%) for 1 week, then trypsinized (treated with 0.25% Trypsin without EDTA for 10 minutes at 37° C.) and transferred to a fresh collagen-1 coated surface and placed in a medium containing all 23 DFPs listed. Over a period of 3-5 days, the cells readily formed three-dimensional pod-like structures, clearly observable by light microscopy (FIG. 11). Some larger pods detached from the culture surface after about 4-6 days in culture, and remained viable, as determined by trypan blue exclusion. The pod-like structures were hypothesized to be aggregations of insulin-producing cells, and subjected to further analysis as described below.

Example 9

Pod-like structures, generated the same manner as described in the previous example, were fixed in 10% formalin and subjected to immunocytochemical analysis first with CK19 monoclonal antibodies, then with C-peptide monoclonal antibodies, as described above. FIG. 12A shows a group of cells (DAPI stained nuclei are blue), some of which are immunopositive for CK19 (green staining). FIG. 12B shows the same group of cells, many of which are positive for C-Peptide, which is produced when the proinsulin molecule synthesized within the cell is cleaved to yield mature insulin; the C-peptide stained cells are red, with a typical granular staining of the cytoplasm. FIG. 12C shows a higher power overlay image, demonstrating colocalization of CK19 and C-peptide in a small subset of cells. Co-stained cells appear yellow-orange on the overlay image.

Example 10

Cells cultured in base medium (negative control), or in Combinations 1, 2 and 3 of the differentiation promoting media, were evaluated for their ability to release insulin and C-peptide into the culture medium. In addition, we assessed whether increasing concentrations of glucose led to the release of a greater quantity of insulin and C-peptide, indicating an islet-like functionality. First, the cells were cultured for 1 week in base medium+EGF (10 ng/ml)+ITS+10% fetal bovine serum (PCM). Then, cells were either subjected to a wash and medium change (non-subcultured), or to a wash, trypsinization/detachment, reseeding, and medium change. Replicate cultures were re-fed with either base medium (serum-free), fresh PCM, or one of the three combinations of differentiation promoting media (all serum-free). After 10 days, differentiation media were removed, cultures were washed 3× with PBS, then re-fed with serum-free base medium containing either 5 mM glucose or 22 mM glucose (final concentration). After 18 hours, the conditioned media were collected and subjected to ELISA analysis with antibodies to either Insulin or C-Peptide (DSL laboratories). FIGS. 13A, 13B and 13C, respectively, show insulin release by nonsubcultured cells, and insulin release and C-peptide release in response to glucose challenge. Since some of the cultures contain insulin, and cells can take insulin up from the medium, production of C-peptide is an important confirmation that the cells are synthesizing insulin de novo from the synthesis and processing of proinsulin. Furthermore, the production of insulin and C-peptide is increased in most cases with increasing glucose concentration, suggesting an islet-like function of cells within these cultures. Note that little insulin or C-peptide is produced in the base medium that contains no DPFs.

Example 11

Both the quantity of insulin and the quantity of DNA were measured in IP cells subjected to differentiation culture with or without enzymatic detachment and subculturing. Cultures were carried out precisely as described in the previous paragraph. DNA was measured utilizing a standard Picogreen assay (Molecular Probes), while insulin was measured by ELISA assay. Total ng of Insulin was divided by total μg of DNA in the sample, thus providing the insulin:DNA ratio value, in order to calculate a ratio of the quantity of insulin present vs. the number of cells present (reflected by DNA content). The results are shown in FIG. 14. In each of the differentiation media combinations, the insulin:DNA ratio is increased compared to base medium, suggesting that more insulin is produced on a per cell basis in the presence of DPFs than when cultured without them. Furthermore, the insulin:DNA ratio is increased slightly in some conditions upon glucose challenge (22 mM glucose vs. 5 mM), suggesting that the cells respond to glucose by releasing a greater quantity of insulin.

Example 12

Insulin-producing cells obtained by the preceding method were subjected to gene expression analysis as described above. Table 5 contains a list of the highest expressed genes, their position on the Clontech atlas 8K gene array, and relative expression of these genes (after normalization). Table 5 is attached hereto as Appendix 1

Example 13

Primary human pancreatic cells were seeded at 0.5×105 cells/cm2 in PCM on a collagen-1 surface and grown for 7 days. Insulin was measured at Days 1, 7, and 10 as follows: Growth medium was removed, wells were washed 3× in phosphate buffered saline. After a pre-incubation for 1 hour at 37 C in base medium without insulin, with 5 mM glucose, media was removed and replaced with either 1) base medium (without insulin) with 5 mM glucose, or 2) base medium (without insulin) with 22 mM glucose. Insulin was measured in cell-conditioned media after 18 hours at 37° C. After 7 days of culture, PCM medium was replaced with either 1) fresh PCM, 2) serum-free base medium, 3) serum free base medium with all 23 differentiating factors, 4) serum-free combination 1, or 5) serum-free combination 2. The results are shown in FIG. 15. After 3 days exposure to the differentiating factors, increased insulin release is noted in presence of differentiating factors. The results on Day 1 argue against the presence of a significant number of insulin-producing cells in the starting material, demonstrating the de novo generation of insulin-producing cells from acinar cells in the primary culture. It can be seen in the Figure that at the end of 10 days, insulin release in response to a glucose challenge is much greater in the DFP media than in the PCM or base medium, verifying the stimulatory effect that the DFPs exert on transformation of glandular epithelial cells into insulin-producing cells.

Example 14

Human pancreatic acinar cells were cultured on a collagen I surface in PCM from Day 1 to Day 7, thus generating a culture of IP cells at Day 7. On Day 7, the EP cells were washed and the PCM medium was replaced with the G09 differentiation medium containing the 30 factors listed in Table 2. At each time point (Days 1, 7, 10 and 14), insulin release was measured by washing the cultures three times with PBS, then challenging the cultures with a 1:1 mixture of DMEM and HAMs F12 containing either 5 mM or 22 mM glucose. After 18 hours of exposure to the glucose, supernatants were collected and insulin measured by ELISA. The results are shown in FIG. 15a.

III. Expression Studies at Several Time Points of Primary Human Acinar Cells that are Expanded, Allowed to Differentiate into IP Cells and then Allowed to Differentiate Further into Insulin-Producing Cells

Example 15

Three independent samples of primary human pancreatic acinar cells were seeded and expanded described above. From Day 0 to Day 8, cells were on collagen I surface, seeded at 104 cells/cm2, in PCM. On Day 8, the medium was changed from PCM to the medium with the active factors shown in Table 2. Cells were fed twice with G09 (50% of medium replaced) between days 8 and 16. The cells remained on the surface throughout the culture process. Cultures were harvested at 3 days after the initial plating (actively trans-differentiating acinar cells), 8 days after plating (IP cells) and 16 days after plating (putative insulin producing cells) and subjected to gene expression analysis, as described in Example 7. mRNA expression data were obtained with 12K microarrays from Clonetech.

Briefly, growth medium was removed from the culture flasks and cells were lysed in trizol LS (Invitrogen) chaotrope/phenol reagent for about 2 minutes by pipetting the lysis solution over the cell layer. Three ml of RNAse free water was added per 9 ml of lysis solution in an Oak Ridge Cetrifuge tube. 2.4 ml chloroform was then added and the solution vigorously vortexed for 1 minute. The aqueous and organic phases were then separated by cetrifugation at 4° C. and the upper aqueous phase containing RNA was removed to a clean PET tube. The RNA was precipitated by isopropanol precipitation, washed with 70% ethanol and redissolved in 200 μl of RNAse free water. A chaotrope lysis reagent was immediately added to the RNA and it was further purified using a Qiagen spin column method with a DNAse digestion step. The purified RNA was finally eluted in 80 μl RNAse free water and stored at −80° C.

Labelled P-33 cDNA probes were prepared from the 30 μg of total RNA from each sample by first enriching for poly A+RNA using a streptavidin-magnetic bead separation method that is part of the Atlas Pure Total RNA Labeeling system. The labeled probes from each sample were hybridized with the plastic human 12 K gene arrays for about 16 hours, the arrays were washed and imaged according to the Atlas array protocols. The Atlas image 2.7 software was used to alighn array images with the array grid template and to exclude false background signals or false signals due to strong signal bleedover. The transcript signals were then extracted from these aligned arrays using the Atlas Image 2.7 software and further statistical analysis of the changes in gene expression were performed.

The raw expression data were analyzed as follows: (1) We filtered out genes that were not expressed at any of the 3 conditions/time points; (2) We normalized all of the microarrays against each other to remove differences from array-to-array and the effects of variability in sample processing, hybridization, etc.; (3) We identified genes which showed a statistically significant difference among the conditions/time points; and (4) We clustered the genes based on their temporal patterns in a way that is consistent with the design of the study and the changes in phenotype.

Table 6 shows expression data for the genes that were identified by the above analysis. This Table is attached hereto as Appendix 2. These identified genes were expressed at high levels at both Day 3 and Day 8, or their expression increased substantially between Day 3 and Day 8. The Table also shows the expression levels of these genes at Day 16, and the mean expression for all three condition/time points. The Table also shows the ratios of expression at various times: “I to A” is the ratio of expression of putative insulin-producing cells (Day 16) to acinar (Day 8) cells; “Int to A” is the ratio of IP cells (Day 8) cells to acinar cells (Day 3).

The data shown in Table 6 were further analyzed by clustering them into one of 17 “classes,” whose features are summarized on the Table. A graphical representation of the characteristics of these 17 classes in presented in FIG. 16.

The data from the Day 8 time points in Table 6 were also grouped with regard to whether the genes expressed at Day 8 in these cells belong to the classes of genes expressed normally in (1) liver and pancreas; (2) pancreas-associated genes; (3) liver-associated genes; or (4) progenitor-associated genes. The results are shown in Table 7.

TABLE 7 BDT Intermediate Cells Genes Expressed in Liver and Pancreatic Pattern of Pancreas Sample 1 Sample 2 Sample 3 Hepatic Pattern of Expression Expression CK18 + + + hepatic lineage acinar cells CK8 + + + hepatic lineage acinar cells CK19 + + + bile duct duct cells CK7 + + + bile duct duct cells HNF1 + + + liver tc factor in beta cells α-1 antitrypsin ++ ++ ++ produced in differentiated hepatocytes yes Notch-1 − − Trace involved in differentiation of cells into developing pancreatic hepatic lineage epithelium α-fetoprotein − − − developing hepatocytes and hepatic developing pancreatic progenitors ducts Notch-3 Trace Trace Trace involved in differentiation of cells into pancreatic mesenchyme hepatic lineage and endothelium Notch-4 Trace Trace Trace- involved in differentiation of cells into pancreatic mesenchyme hepatic lineage and endothelium Jagged-2 + + + involved in differentiation of cells into yes hepatic lineage pi-glutathione s + + ++ developing liver duct cells and centroacinar transferase (pi-GST) cells γ-glutamyl transferase − − − developing bile duct acinar cells Pancreatic Pattern of Pancreas-Associated Genes Sample 1 Sample 2 Sample 3 Hepatic Pattern of Expression Expression carbonic anhydrase − − Trace no duct cells CF transmemb conductance regulator − − Trace no duct cells elastase − − − no acinar cells amylase − − − no acinar cells insulin + Trace Trace no islet somatostatin Trace Trace Trace no islet Pancreatic Polypeptide + + Trace no islet Glucagon − − − no islet Liver-Associated Pancreatic Pattern of Genes Sample 1 Sample 2 Sample 3 Hepatic Pattern of Expression Expression Sialyltransferase-6 − − − produced in differentiated hepatocytes no Liver-specific bHLH + + + liver-specific Tc factor no transcrip factor Thy-1 + + + hepatic oval cell marker no Glucose-6-phosphatase − − Trace hepatic lineage, progenitors and adult No Glutamine synthetase − − Trace hepatocyte No Carbamoyl phosphate − − − hepatocyte no synthetase-1 Dipeptidylpeptidase IV − − − hepatocyte no C/EBP-α ++ ++ + liver-specific Tc factor *turned on and upregul during hepatization of pancreas (copper-deficient diet) C/EBP-beta ++ ++ ++ liver-specific Tc factor *turned on and upregul during hepatization of pancreas (copper-deficient diet) Progenitor Cell-Associated Genes Sample 1 Sample 2 Sample 3 Tissue Musashi-1 − − − Intestine Nestin − − − Pancreas/Neuronal CD34 − − − Hematopoietic Thy-1 − − − Hepatic progenitors BMP-2 − − − Neuronal BMPRcIA − − Trace Mesenchyme c-kit − − − Liver/Pancreas/Neuronal chromogranin A Trace Trace Trace Neuroendocrine/Liver/Intestine PDX-1 − − + Pancreas

As can be seen, at Day 8 IP cells no longer expressed genes consistent with pancreatic acinar cells, nor did they express a complement of genes specific for pancreatic ductular cells. The IP cells expressed low levels of some markers associated with pancreatic islets, including insulin, somatostatin and pancreatic polypeptide, suggesting that at least some cells in the population are competent to express endocrine genes of the pancreatic islets.

Surprisingly, the IP cells also expressed several liver-specific transcription factors (e.g., C/EBP alpha, C-EBP-beta) and other markers of mature and developing liver, including low levels of Thy-1, a marker associated with hepatic “oval” stem cells. This suggests that the differentiating cells were not moving simply from pancreatic acinar to pancreatic ductal, but had developed into a cell with both hepatic and pancreatic characteristics, while not fitting into any single gene expression profile of one of these cell types. The cells generated in this example resemble the cells that emerge from the pancreas of rodents that are fed a copper-deficient diet. (See, e.g. Rao et al., 1988). The pancreas of such animals goes through an acute phase of pancreatitis followed by “hepatization” of liver (which means cells that begin to express hepatic genes rather than pancreatic genes). Liver-like cells have also been reported in human fetal pancreas (Tsanadis et al., 1995) Isolated cells generated by the methods of the present invention (e.g., by propagating primary acinar cells or other types of endodermal cells or progenitor cells by the methods of the invention) are to be distinguished from naturally occurring cells that may have some of the characteristics of IP cells, such as oval cells or cells isolated from the pancreas of a rodent on a copper-deficient diet.

Cells having the characteristics of these IP cells may be useful for, e.g., therapeutic approaches in the treatment of diabetes. Furthermore, although the cells in this example were derived from pancreas, other epithelial tissues, or perhaps even any endoderm-derived tissue, may provide additional sources of cells that can be differentiated into cells having a similar phenotype. Suitable tissue types include, e.g., liver or intestine. These IP cells express genes associated with pancreas, liver, intestine and neuronal tissues. For example, they express mucin, CK19 and CK7, which are common markers associated with duct cells in the pancreas, liver and intestine. Thus, the gene expression pattern seen in these IP cells may serve as a predictive measure for cells derived from each of these tissues for the purpose of generating insulin-producing cells. Furthermore, IP cells may, under appropriate conditions, give rise, not only to pancreatic islet cells, but also to hepatocytes or any endoderm-derived tissue.

The disclosures of the following references, cited above in part, relate to the present invention:

  • WO 02/29010 A2 (Kerr-Conte);
  • Bonner-Weir, S. et al., Proc. Natl. Acad. Sci. USA 97: 7999-8004 (2000),
  • Bouwens, L., Microsc. Res. Tech. 43: 332-6 (1998),
  • Bowens, L. et al. Diabetologia 41:629-33 (1998);
  • Gmyr, V. et al., Diabetes 49:1671-80 (2000);
  • Gmyr, V. et al. Cell Transplant 10:109-21 (2001),
  • Gmyr, V. et al. Diabetes 49:1671-80 (2000),
  • Hall, P. A. et al., J. Pathol. 166: 97-103 (1992);
  • Kerr-Conte, J. et al., Diabetes 45:1108-14 (1996);
  • Kerr-Conte, J. et al., Transplant Proc 27:3268 (1985);
  • Pattou F. et al., Bull. Acad. Natl. Med. 184:1887-99 (2000);
  • Rao, M S et al Biochem Biophys Res Comm. 156:131-6 (1988);
  • Rooman, Ilse et al., Diabetes 51: 686-90 (2002);
  • Rooman, I, et al. Diabetologia 43:907-14 (2000);
  • Rooman, I. et al., Gastroenterology 121: 940-9 (2001);
  • Trivedi, N. et al. Endocrinology 142:2115-22 (2001);
  • Tsanadis, G. et al. Histol. Histopathol. 10:1-10 (1995);
  • Wang, R. N. et al., Diabetologia 38:1405-11(1995);
  • U.S. Pat. No. 6,011,647 (Ammon Peck).

The embodiments illustrated and discussed in the present specification are intended only to teach those skilled in the art the best way known to the inventors to make and use the invention, and should not be considered as limiting the scope of the present invention. The exemplified embodiments of the invention may be modified or varied, and elements added or omitted, without departing from the invention, as appreciated by those skilled in the art in light of the above teachings. It is therefore to be understood that, within the scope of the claims and their equivalents, the invention may be practiced otherwise than as specifically described.

The entire disclosure of all applications, patents and publications, cited above and in the figures are hereby incorporated in their entirety by reference.

Appendix 1

TABLE 5 GENE Position on Atlas 8K Array Relative Expression, Sample 1 Relative Expression,Sample 2 aquaporin 5 7547 4539 4550 actin, beta 3952 3598 3442 actin, beta 8176 3047 3747 growth hormone secretagogue receptor 6846 2092 1710 profilin 1 448 1580 1246 special AT-rich sequence binding protein 1 3035 1437 886 (binds to nuclear matrix/scaffold- associating DNA's) cardiac-specific homeo box 2050 1395 2850 CCAAT/enhancer binding protein (C/EBP), 1588 1374 1671 beta RAS guanyl releasing protein 2 (calcium 8262 1263 1616 and DAG-regulated) cartilage paired-class homeoprotein 1 6677 1166 1241 paired-like homeodomain transcription 6805 1113 756 factor 1 transcription factor 21 7621 1063 801 CD3E antigen, epsilon polypeptide (TiT3 8054 994 1113 complex) CD151 antigen 5613 935 808 ATPase, Ca++ transporting, plasma 7940 919 876 membrane 2 ficolin (collagen/fibrinogen domain- 824 901 829 containing) 3 (Hakata antigen) inositol polyphosphate phosphatase-like 1 5989 832 425 protein tyrosine phosphatase, receptor 8367 806 810 type, S integrin, alpha 3 (antigen CD49C, alpha 3 1743 758 647 subunit of VLA-3 receptor) syntaxin 1A (brain) 6851 743 658 parathymosin 7135 725 852 thymosin, beta 10 7436 709 1617 midkine (neurite growth-promoting factor 2) 2470 682 802 arylsulfatase A 3147 678 3084 calbindin 2, (29 kD, calretinin) 7000 676 786 serine (or cysteine) proteinase inhibitor, 5214 668 678 clade A (alpha-1 antiproteinase, antitrypsin), member 1 retinal G protein coupled receptor 7972 653 696 myosin regulatory light chain 2, smooth 2499 638 561 muscle isoform butyrate response factor 1 (EGF-response 7325 630 646 factor 1) type I transmembrane receptor (seizure- 7583 589 394 related protein) type I transmembrane receptor (seizure- 7583 589 394 related protein) procollagen C-endopeptidase enhancer 3593 576 713 mitogen-activating protein kinase kinase 7069 558 571 kinase kinase 2 protease, serine, 1 (trypsin 1) 6323 558 656 pancreatitis-associated protein 4576 536 2177 angiotensin receptor 1B 4093 516 491 stratifin 6489 503 581 keratin 17 7903 500 364 somatostatin receptor 3 6872 432 433 myosin-binding protein H 4692 428 96 ephrin-A5 4202 411 381 RAP1, GTPase activating protein 1 1965 407 263 chymotrypsinogen B1 6604 405 830 ankyrin-like with transmembrane domains 1 3577 395 431 Misshapen/NIK-related kinase 2439 391 341 bone morphogenetic protein 6 4492 381 308 splicing factor proline/glutamine rich 713 375 662 (polypyrimidine tract-binding protein- associated) claudin 12 2720 370 378 matrix metalloproteinase 23A 7491 368 138 neurogranin (protein kinase C substrate, 4465 366 335 RC3) dopamine receptor D2 1649 362 234 cardiotrophin 1 5283 359 507 CCAAT/enhancer binding protein (C/EBP), 7237 359 645 alpha paired box gene 9 5206 335 201 protein tyrosine phosphatase, receptor 8235 331 250 type, N keratin 8 7215 327 449 claudin 7 280 325 173 trophinin associated protein (tastin) 462 323 360 neuronal thread protein 8356 322 366 basic helix-loop-helix domain containing, 6734 318 215 class B, 2 annexin A2 4467 290 226 cathepsin D (lysosomal aspartyl protease) 7370 289 600 Bicaudal D (Drosophila) homolog 1 6822 284 217 lectin, galactoside-binding, soluble, 1 7331 280 310 (galectin 1) keratin 7 7171 278 481 glyceraldehyde-3-phosphate 3953 278 307 dehydrogenase aquaporin 6, kidney specific 7591 277 258 TNF receptor-associated factor 1 6037 269 270 Rho GDP dissociation inhibitor (GDI) alpha 5565 267 321 calcium channel, voltage-dependent, 3142 260 207 gamma subunit 4 glutamate receptor, ionotropic, kainate 1 4776 244 296 CCR4-NOT transcription complex, subunit 4 983 244 428 filamin A, alpha (actin-binding protein-280) 3457 241 233 peanut (Drosophila)-like 1 711 233 310 enhancer of rudimentary (Drosophila) 5921 231 405 homolog endothelin converting enzyme 1 7835 229 197 protocadherin 17 2483 223 208 aquaporin 8 7679 217 145 synapsin I 4871 216 164 Tubulin, alpha, brain-specific 2827 212 345 CD44 antigen (homing function and Indian 7848 207 141 blood group system) cerebral cavernous malformations 1 2731 205 116 insulin-like 3 (Leydig cell) 666 202 365 adenylate cyclase activating polypeptide 1 4489 200 74 (pituitary) hairless (mouse) homolog 5185 196 36 insulin 4427 190 44 granulin 928 184 201 granulin 928 184 201 early growth response 1 2111 178 136 cyclin-dependent kinase inhibitor 1A (p21, 7852 175 108 Cip1) stem cell growth factor; lymphocyte 1606 174 152 secreted C-type lectin CD4 antigen (p55) 5608 172 143 PCTAIRE protein kinase 1 6334 161 78 Rho GTPase activating protein 6 1035 160 220 G protein-coupled receptor 37 (endothelin 6318 158 35 receptor type B-like) syndecan 4 (amphiglycan, ryudocan) 3154 157 147 PCTAIRE protein kinase 3 8050 155 159 empty spiracles (Drosophila) homolog 2 2084 150 207 transglutaminase 1 (K polypeptide 6674 150 101 epidermal type I, protein-glutamine-gamma- glutamyltransferase) potassium voltage-gated channel, 1335 147 62 subfamily G, member 2 aldehyde dehydrogenase 4 (glutamate 5985 147 207 gamma-semialdehyde dehydrogenase; pyrroline-5-carboxylate dehydrogenase) E1A binding protein p300 1433 144 197 LIM homeobox transcription factor 1, beta 8211 143 89 eukaryotic translation elongation factor 2 4536 134 150 mitogen-activated protein kinase kinase 5462 129 92 kinase 10 PPAR(gamma) angiopoietin related protein 3074 129 56 homeo box A5 7037 128 87 CD63 antigen (melanoma 1 antigen) 7769 124 91 nuclear receptor coactivator 3 4181 119 84 CD68 antigen 443 118 256 transmembrane 4 superfamily member 7 1571 117 29 pancreatic polypeptide 2735 116 136 endothelin type b receptor-like protein 2 6656 114 74 neurogenin 1 5772 113 91 insulin receptor substrate 2 6016 110 130 glutamate receptor, ionotropic, N-methyl D- 4702 109 58 asparate-associated protein 1 (glutamate binding) neurotrophin 5 (neurotrophin 4/5) 8259 108 89 pyrimidinergic receptor P2Y, G-protein 3857 105 65 coupled, 6 empty spiracles (Drosophila) homolog 1 2040 103 87 chromobox homolog 2 (Drosophila Pc 2832 101 139 class) heart and neural crest derivatives 2146 92 129 expressed 1 transglutaminase 2 (C polypeptide, protein- 7731 92 74 glutamine-gamma-glutamyltransferase) enolase 1, (alpha) 1389 92 205 thyroid transcription factor 1 4519 89 60 keratin 19 5923 88 223 Deleted in split-hand/split-foot 1 region 3641 87 104 glutathione peroxidase 4 (phospholipid 1874 84 72 hydroperoxidase) aristaless (Drosophila) homeobox 1783 81 103 GATA-binding protein 4 659 80 110 transcription factor 1, hepatic; LF-B1, 712 80 136 hepatic nuclear factor (HNF1), albumin proximal factor heat shock transcription factor 1 6708 79 57 liver-specific bHLH-Zip transcription factor 765 77 188 liver-specific bHLH-Zip transcription factor 765 77 188 eukaryotic translation initiation factor 3, 6280 76 94 subunit 4 (delta, 44 kD) eukaryotic translation initiation factor 3, 6280 76 94 subunit 4 (delta, 44 kD) gamma-aminobutyric acid (GABA) A 3720 70 178 receptor, alpha 6 retinoic acid receptor, gamma 5191 70 109 homeo box D9 1776 69 34 MAD1 (mitotic arrest deficient, yeast, 1946 63 38 homolog)-like 1 homeo box A4 7177 57 103 Thy-1 cell surface antigen 559 57 87 talin 603 53 84 bone morphogenetic protein receptor, type 332 53 45 II (serine/threonine kinase) hepatocyte nuclear factor 3, alpha 72 52 60 ryanodine receptor 2 (cardiac) 5244 47 40 signal transducer and activator of 3661 40 35 transcription 6, interleukin-4 induced

TABLE 6 SwissProt Spot geneName day3 day8 day16 P04270 E19ab2 actin; alpha; cardiac muscle 1198.174 760 5955.077 O95996 N17ab2 adenomatous polyposis coli like 2708.542 5180 7594.139 Q14697 G02ef8 alpha glucosidase II alpha subun 306.0691 350 775.3358 P14209 G23ab7 antigen identified by monoclonal 389.822 507 1238.43 P30530 G14ef5 AXL receptor tyrosine kinase 314.4639 288 634.5658 O43770 I23ab3 B-cell CLL/lymphoma 7C 700.573 1050 1504.52 O43852 P08ab3 calumenin 801.582 1290 4720.807 O75718 O24cd6 cartilage associated protein 430.4432 256 1090.59 Q9Y3C0 G14ef2 CGI-116 protein 181.0293 301 416.7246 P78369 G09cd6 claudin 10 1176.087 742 2598.595 P08572 P08ef6 collagen; type IV; alpha 2 1130.23 1350 4684.425 P11802 B05ef5 cyclin-dependent kinase 4 914.1579 978 2342.994 Q16555 O07ab4 dihydropyrimidinase-like 2 114.6165 164 921.1473 P33316 H23ab5 dUTP pyrophosphatase 177.2032 238 541.5382 P07992 K20ef6 excision repair cross-complemen 362.031 415 907.7933 O75636 B14cd3 ficolin (collagen/fibrinogen doma 1081.127 1010 4327.606 Q9UBA6 B19ef4 G8 protein 370.6842 578 1489.206 Q9Y5P5 P08ef7 GDP-mannose pyrophosphoryla 171.1216 198 414.0862 O75293 E02ef7 growth arrest and DNA-damage- 194.3626 203 386.6833 P50152 C05ab6 guanine nucleotide binding prote 204.743 150 497.3097 Q9NX09 C05gh3 HIF-1 responsive RTP801 348.8574 253 1032.929 P05204 J22ab7 high-mobility group (nonhistone 2067.865 1120 6059.895 Q9P0P2 C17ef3 homolog of yeast MOG1 325.8407 378 682.7568 Q9NWF8 L15gh2 hypothetical protein FLJ10055 172.167 241 374.3 Q9NWV4 B17gh2 hypothetical protein FLJ20580 221.4432 280 483.5381 Q9P0S8 A21ef3 hypothetical protein HSPC195 153.824 165 330.9111 Q9BWS9 P04gh5 hypothetical protein MGC3234 196.9154 161 427.2066 Q9BSK0 K21gh8 hypothetical protein MGC4415 156.4692 117 684.3425 Q9Y6M1 P09cd6 IGF-II mRNA-binding protein 2 135.2566 153 408.5101 Q9NQX7 H02gh7 integral membrane protein 3 478.2728 481 1102.244 P08648 E23ef7 integrin; alpha 5 (fibronectin rece 183.4629 124 478.7266 O00410 J24ab6 karyopherin (importin) beta 3 326.6874 196 629.7656 P07195 N16ab6 lactate dehydrogenase B 1003.971 1200 5593.079 P09382 N22ab6 lectin; galactoside-binding; solub 19170.52 35400 78086.75 O75427 P20ab6 leucine-rich repeat protein; neur 174.9605 231 543.3883 Q16553 A15ab7 lymphocyte antigen 6 complex; I 425.8933 494 938.4504 O75900 O05cd4 matrix metalloproteinase 23A 381.2184 297 851.7221 Q9UNF1 H16ef7 melanoma antigen; family D; 2 193.8125 219 659.9701 P13995 J16cd6 methylene tetrahydrofolate dehy 321.4878 226 759.6021 O00265 G19cd8 microtubule-associated protein; 189.7616 234 377.5576 P27361 B13ef5 mitogen-activated protein kinase 358.0872 382 720.3119 P24844 E18cd6 myosin; light polypeptide 9; regul 5480.451 7380 22518.95 Q9NVD4 J10gh2 N-acetylneuraminic acid phosph 153.4762 167 390.6642 Q9Y617 N22ef8 phosphoserine aminotransferase 169.9503 250 1238.851 O95356 A11gh7 pituitary tumor-transforming 3 237.2126 192 2276.181 Q9Y5X6 G04cd6 plasma glutamate carboxypeptid 169.6268 142 366.6202 Q15113 G20ab8 procollagen C-endopeptidase en 497.3967 402 2628.947 O15460 D20cd4 procollagen-proline; 2-oxoglutar 262.1395 433 756.4003 O43556 I19gh1 sarcoglycan; epsilon 172.7191 215 349.304 P50454 M17ab6 serine (or cysteine) proteinase in 339.1762 612 4091.161 Q92853 A23cd8 similar to vaccinia virus HindIII K 444.062 553 997.4551 Q16658 P20cd1 singned-like (fascin homolog; sea 262.7872 479 1472.155 Q9Y4Y8 E18cd7 Sm protein F 257.2026 278 548.9705 Q9BVH9 D18gh7 thioredoxin related protein 522.0262 481 1903.964 Q9HBB0 L08gh8 Thy-1 co-transcribed 327.3502 374 1110.527 P01033 P09ef7 tissue inhibitor of metalloprotein 1236.457 1500 13029.41 Q15582 L20ef6 transforming growth factor; beta- 1221.083 2060 8540.86 Q01995 M07cd2 transgelin 3307.821 3880 18534.27 Q13641 B05ab2 trophoblast glycoprotein 479.6488 426 1399.786 P06468 G08cd2 tropomyosin 2 (beta) 339.2292 589 13203.05 P51784 M21cd4 ubiquitin specific protease 11 158.0478 194 491.1246 P03996 E17ab2 actin; alpha 2; smooth muscle; a 412.1187 1940 41801.34 P08123 P02ef6 collagen; type I; alpha 2 186.5666 576 14565.36 P24821 A05ef7 hexabrachion (tenascin C; cytota 355.495 918 2371.983 Q9NVA2 F13gh3 hypothetical protein FLJ10849 374.1496 861 3471.789 P40261 M09cd1 nicotinamide N-methyltransferase 1060.579 2310 5683.533 Q15063 C01ef7 osteoblast specific factor 2 (fascl 276.634 795 8328.222 P09486 A09ef7 secreted protein; acidic; cysteine 404.2839 2760 63837.2 P35625 K20ef5 tissue inhibitor of metalloprotein 216.254 619 10078.17 Q9H2L5 G06gh8 AD037 protein 361.2297 681 158.8121 P15121 C18ab2 aldo-keto reductase family 1; me 2342.744 5380 2337.052 P08582 B14ef5 antigen p97 (melanoma associat 299.1375 595 80.80392 P20292 E06ab2 arachidonate 5-lipoxygenase-act 100.0016 687 203.2911 O15342 A13ab3 ATPase; H+ transporting; lysoso 6063.171 16500 6160.831 Q9BXJ0 H18gh6 C1q and tumor necrosis factor re 180.2978 350 154.1441 Q9NRJ3 P09gh4 CC chemokine CCL28 250.0021 1830 763.2866 P05305 F17ab5 endothelin 1 866.4561 1810 403.431 P09341 A04ab6 GRO1 oncogene (melanoma gro 933.2938 4770 1006.711 Q92730 O14ef4 GTP-binding protein 653.8575 2760 542.7528 Q9H5K0 L10gh5 hypothetical protein FLJ23360 151.2029 296 130.3196 P18564 E21ef7 integrin; beta 6 540.0362 1180 233.0055 P14316 B16ef6 interferon regulatory factor 2 252.3603 472 255.7047 P40305 O20ab7 interferon; alpha-inducible protei 117.3152 766 218.2471 P05161 B21cd5 interferon-stimulated protein; 15 302.3796 983 326.6346 P42701 A06ef7 interleukin 12 receptor; beta 1 1227.347 22100 1333.521 P09237 J15ef1 matrix metalloproteinase 7 (matri 9598.545 87300 19849.69 P16860 O13ab8 natriuretic peptide precursor B 4340.214 12900 1260.906 P21359 L16ab7 neurofibromin 1 (neurofibromato 132.483 292 155.0822 P02775 B07ef7 pro-platelet basic protein (includ 33.98656 1400 265.2119 Q9UDQ9 J22gh4 SBBI26 protein 121.5886 1080 238.8624 O75635 P14cd3 serine (or cysteine) proteinase in 232.6336 3890 326.2581 P02735 A11cd3 serum amyloid A1 496.9578 17400 957.6141 O60635 F10cd5 tetraspan 1 321.8888 843 177.6479 P50591 C09cd4 tumor necrosis factor (ligand) su 536.7773 1550 476.2305 Q03169 I10ef7 tumor necrosis factor; alpha-indu 366.7502 1260 326.6536 Q9C075 N11ef8 type I intermediate filament cytok 848.9829 4200 401.4854 P02248 A01cd3 ubiquitin C 155.6735 892 62.04595 O95497 A15cd5 vanin 1 309.1556 1840 510.7208 Q14202 B15cd5 zinc finger protein 261 199.6246 1040 247.9161 P15514 M02ef7 amphiregulin (schwannoma-deri 103.1419 405 65.66067 Q9BZL9 I21gh8 B aggressive lymphoma gene 126.3951 211 84.56927 P30991 D14ef5 chemokine (C—X—C motif); recept 64.37115 260 120.2328 P29400 H13ab3 collagen; type IV; alpha 5 (Alport 53.50943 374 141.1609 Q9UK22 H22cd7 F-box only protein 2 87.59822 217 120.3781 Q16769 O15cd8 glutaminyl-peptide cyclotransfera 89.90252 195 113.0683 P02261 M06gh6 H2A histone family; member I 65.46028 263 126.664 P20769 D03ef1 immunoglobulin heavy constant 101.245 176 102.5687 P52945 I12ab6 insulin promoter factor 1; homeo 74.60504 351 86.42558 Q14496 F21cd6 interferon-induced protein 44 99.27101 286 98.28057 P01583 F15ef7 interleukin 1; alpha 103.386 375 66.6314 P01584 F17ef7 interleukin 1; beta 116.7675 415 119.0156 Q9GZM1 I20gh7 NDRG family member 4 102.1328 348 101.569 P25105 G15ef5 platelet-activating factor receptor 97.43121 356 80.47935 P58294 O14gh8 prokineticin 1 precursor 79.98286 241 137.5167 P23471 A06ef6 protein tyrosine phosphatase; re 85.55935 346 93.65845 O88386 D10ef3 RAB10; member RAS oncogene 123.2003 399 68.13944 P10826 I08gh6 retinoic acid receptor; beta 67.98871 241 120.9469 O95786 I24ef3 RNA helicase 112.9366 241 89.32396 P02778 O10ef7 small inducible cytokine subfamil 65.03395 418 86.09019 P80162 F14cd1 small inducible cytokine subfamil 54.00821 311 129.2639 P43005 N23ef5 solute carrier family 1 (neuronal/ 99.30514 189 110.8119 P01375 O09ef6 tumor necrosis factor (TNF supe 138.6153 386 75.13436 Q16890 G04cd2 tumor protein D52-like 1 103.5477 191 98.01862 Q9H949 K11gh5 WW45 protein 111.8812 218 79.54574 Q9H4G4 O06gh5 17 kD fetal brain protein 88.61746 223 532.2979 Q14040 B15ef1 collagen; type VI; alpha 1 38.27203 209 4724.413 P12110 B17ef1 collagen; type VI; alpha 2 88.00282 164 3835.637 P02751 K15ef1 fibronectin 1 4.441362 152 4171.603 P14652 N23ab6 homeo box B2 62.71629 291 3571.974 P08476 D15ef7 inhibin; beta A (activin A; activin 64.38161 318 854.6532 P17936 D07ab6 insulin-like growth factor binding 38.22268 349 1302.669 Q9Y4K0 P18ab6 lysyl oxidase-like 2 75.91549 260 2525.644 P03956 N05ef7 matrix metalloproteinase 1 (inter 106.2193 203 590.2622 P39900 N15ef7 matrix metalloproteinase 12 (ma 18.2367 381 1219.953 P55001 G09ab7 microfibrillar-associated protein 2 99.33548 526 3302.631 Q9NYR0 O07gh7 SH3-domain kinase binding prot 34.69271 197 656.4675 O43623 D06ef4 snail homolog 2 (Drosophila) 96.88079 292 3028.508 P09936 I13cd4 ubiquitin carboxyl-terminal ester 48.30052 219 1523.166 Q02952 J11ab2 A kinase (PRKA) anchor protein 103.9756 364 229.1446 Q99541 I19ab2 adipose differentiation-related p 67.38509 182 146.1347 P54284 N17ab3 calcium channel; voltage-depend 106.3248 227 254.9633 Q13269 G14ab5 cAMP responsive element bindin 100.6639 193 217.7521 Q9NPF2 M02ef4 chondroitin 4-sulfotransferase 133.8375 192 303.01 Q9H7A5 F12gh7 chromosome 20 open reading fra 98.71521 179 208.0134 Q9H9Q2 L23gh5 COP9 constitutive photomorpho 86.57682 115 184.3088 P42771 D17ef5 cyclin-dependent kinase inhibitor 43.35217 471 355.7426 Q14650 J20ef4 cytoplasmic FMR1 interacting pr 132.5759 272 321.6348 Q96IK6 F14gh6 DKFZP434C245 protein 145.227 104 91.06477 P12034 D05ef7 fibroblast growth factor 5 60.2377 259 317.6018 Q93079 M20gh6 H2B histone family; member J 144.6906 428 271.2983 Q9P016 A10ef8 HSPC144 protein 123.4601 348 399.4935 Q9HBI5 M09gh4 HT021 116.3605 276 309.5798 Q9BY45 O24gh8 HTPAP protein 78.49388 109 177.2043 P08397 G18ab6 hydroxymethylbilane synthase 139.0857 188 260.8417 Q9BUV0 M06gh4 hypothetical protein dJ465N24.2. 68.40543 152 167.5592 Q9H9A2 N22gh6 hypothetical protein DKFZp762 82.54725 110 169.5379 Q9NUV6 P09gh3 hypothetical protein FLJ11113 87.43713 178 136.6771 Q9NXF7 C20gh2 hypothetical protein FLJ20280 66.49705 143 170.7367 Q9H6V0 M05gh5 hypothetical protein FLJ21839 116.3704 258 323.3964 Q9BUW5 K21gh6 hypothetical protein MGC4707 80.31127 170 203.9516 Q9H765 I15gh6 hypothetical protein MGC5540 106.3949 220 206.6405 Q14157 N23gh1 KIAA0144 gene product 95.13957 147 147.7214 Q9Y2D8 A07ef8 KIAA0923 protein 84.1225 237 206.8269 Q9H6Z3 E24gh5 kinesin family member 13A 111.6382 206 238.8822 Q99748 J24ab8 neurturin 123.7486 150 246.4754 Q9NVD7 D11gh3 parvin; alpha 82.67948 140 230.66 O43175 H24cd6 phosphoglycerate dehydrogenas 98.81456 119 192.3326 Q9Y253 E24cd1 polymerase (DNA directed); eta 108.2715 101 157.8762 P24158 M05ef5 proteinase 3 (serine proteinase; 87.66238 280 172.8525 Q9U8K7 M21ef3 RAB; member of RAS oncogene 110.9871 189 313.4316 Q13636 K19cd7 RAB31; member RAS oncogene 76.36263 118 170.0352 Q9UIC2 L10ef2 RNB6 80.78879 171 194.395 Q9NVQ7 K12gh3 Sec61 alpha form 2 82.6036 143 162.0674 O75368 J08cd1 SH3 domain binding glutamic aci 92.82513 212 196.8753 O95863 N01cd2 snail homolog 1 (Drosophila) 76.58448 134 157.9807 Q9UL01 H01cd8 squamous cell carcinoma antige 86.70353 111 176.4557 Q16226 N05cd6 thioredoxin interacting protein 111.1384 454 529.2322 P07996 A11ef7 thrombospondin 1 79.00174 139 163.2593 Q99081 F10ef6 transcription factor 12 (HTF4; he 112.2294 181 256.0348 O95922 L06ef7 tubulin tyrosine ligase-like 1 73.12945 245 253.9213 P15036 H18ef6 v-ets erythroblastosis virus E26 149.9259 114 83.55955 O95337 D04ef8 weakly similar to glutathione per 69.55111 164 284.3593 Q9H1B5 M18gh5 xylosyltransferase II 81.87715 106 174.2539 P55263 K07ab2 adenosine kinase 891.6698 720 299.6337 P51648 A22ab2 aldehyde dehydrogenase 3 famil 1955.203 1390 507.3786 P50995 I08ab2 annexin A11 4888.71 3870 1773.94 P12429 I14ab2 annexin A3 9711.235 10800 1720.452 P05026 L22ab2 ATPase; Na+/K+ transporting; b 3965.733 5290 1976.367 P00751 M07ab3 B-factor; properdin 2984.309 2460 1178.473 Q9HA23 E10gh6 calponin like transmembrane dor 480.5263 528 193.0456 Q16170 M17ab3 carcinoembryonic antigen-relate 984.7628 1230 212.7712 P25774 P07ab5 cathepsin S 857.9751 776 228.9093 P21926 J13ef7 CD9 antigen (p24) 2011.966 3500 833.332 Q9H2A7 M19gh5 chemokine (C—X—C motif) ligand 1 650.7961 842 235.8205 O14493 G21ab4 claudin 4 1919.128 2480 799.5104 P12277 M06ab4 creatine kinase; brain 373.8119 617 193.0681 Q9NYS7 E20ef4 CS box-containing WD protein 596.6891 384 211.1821 P53355 D09ab5 death-associated protein kinase 1325.243 1260 558.9756 O15205 D17cd6 diubiquitin 7363.301 14700 2196.358 Q9UFZ2 C23ef8 DKFZP564K247 protein 1325.797 1060 313.5237 P28562 M22ab5 dual specificity phosphatase 1 2077.188 1680 754.9876 Q16690 B21ab4 dual specificity phosphatase 5 485.6475 305 155.0161 Q9UJW0 H10ef1 dynactin 4 (p62) 778.5079 662 335.9831 E13gh5 ectonucleotide pyrophosphatase 233.9728 378 183.3797 P00533 A06ef5 epidermal growth factor receptor 263.2516 334 182.4044 Q13113 J02cd5 epithelial protein up-regulated in 13324.19 15500 2641.961 P28161 M09ab6 glutathione S-transferase M2 (m 1020.341 690 217.4433 Q03013 L06ab3 glutathione S-transferase M4 333.2767 465 210.8696 P52594 A18ab7 HIV-1 Rev binding protein 439.4544 468 252.8058 Q9NWT9 D09gh2 hypothetical protein FLJ20607 1062.388 757 368.3558 Q9BZR4 L12gh7 hypothetical protein HT036 748.0681 844 160.1449 Q9BW25 A19gh6 hypothetical protein MGC3101 315.4695 409 150.4768 P16144 I16ab6 integrin; beta 4 490.7243 672 157.31 P10145 O22ef7 interleukin 8 6902.736 13300 1783.339 Q05084 G10ab7 islet cell autoantigen 1 (69 kD) 600.5671 588 209.1329 Q9Y484 E14cd7 JM5 protein 1335.218 2010 938.9827 P14923 M23ef6 junction plakoglobin 1969.949 2610 912.3081 P05783 N06ef6 keratin 18 17317.24 12500 2306.177 P08727 L06ab6 keratin 19 4025.258 2800 631.8404 P08729 N14ef6 keratin 7 11605.48 11100 1888.38 P05787 N16ef6 keratin 8 11031.01 7880 1694.024 O14782 H22ab6 kinesin family member 3C 366.3528 652 242.2822 O00515 D05ab7 ladinin 1 3562.632 2040 824.2377 P80188 D13ab7 lipocalin 2 (oncogene 24p3) 5234.435 9070 664.0466 Q9UQ53 G02ef3 mannosyl (alpha-1; 3-)-glycoprot 1485.546 931 398.5069 P80294 D15gh6 metallothionein 1H 327.8489 366 208.8705 O75394 M10cd5 mitochondrial ribosomal protein 441.6574 646 213.7295 Q9Y376 H18ef2 MO25 protein 860.3225 1410 550.0258 P15941 H22ab7 mucin 1; transmembrane 2330.649 1250 487.1995 Q16301 H11cd4 myelin transcription factor 2 2433.02 2560 545.0513 Q99836 M07ab7 myeloid differentiation primary re 1088.39 1110 413.4864 P24001 H08cd4 natural killer cell transcript 4 49232.84 71300 13531.68 Q9C002 O12gh8 normal mucosa of esophagus sp 8605.554 17700 4423.686 P25963 A16ef1 nuclear factor of kappa light poly 938.908 1270 605.6118 P00491 L18ab7 nucleoside phosphorylase 820.4015 500 250.4586 P49763 O20ef7 placental growth factor; vascular 5604.053 12600 1723.953 Q9Y342 A13ef2 plasmolipin 942.5595 983 300.2833 P43490 H04cd5 pre-B-cell colony-enhancing fact 2261.72 1730 651.3251 Q99988 B23ef7 prostate differentiation factor 1470.061 2930 681.8854 Q9UJY1 B05ef3 protein kinase H11 1836.927 2080 544.441 Q9H1C7 O10gh8 putative nuclear protein ORF1-F 11454.74 14800 3062.014 P51149 A21ef6 RAB7; member RAS oncogene f 3422.13 5250 2267.107 P51151 J22cd4 RAB9A; member RAS oncogene 1882.687 1580 721.6194 P15153 C17ef6 ras-related C3 botulinum toxin s 383.0769 418 213.0301 P52566 I19ef1 Rho GDP dissociation inhibitor ( 986.1501 788 352.0789 P01011 I08ef7 serine (or cysteine) proteinase in 40450.89 43700 10172.44 P05120 P07ef7 serine (or cysteine) proteinase in 24922.82 38200 2879.818 O14508 M13ef6 STAT induced STAT inhibitor-2 1511.844 1490 420.453 Q9Y6N5 G13gh4 sulfide dehydrogenase like (yeas 823.7665 871 284.0637 O00161 C23cd4 synaptosomal-associated protein 1077.833 1340 687.0432 P31431 F24cd1 syndecan 4 (amphiglycan; ryudo 2109.871 3080 887.6687 O15533 B16ef7 TAP binding protein (tapasin) 313.1585 424 162.3501 P17987 E11ef5 t-complex 1 495.6787 298 157.6175 O14746 O20ef6 telomerase reverse transcriptase 264.8687 373 151.5845 P30408 C06ef1 transmembrane 4 superfamily m 16658.44 17400 6051.147 Q9HCN3 E07gh5 transmembrane protein 8 (five m 947.8492 1010 462.0955 Q16149 B15cd1 transporter 1; ATP-binding casse 862.1561 1100 480.8685 Q9Y2A9 C22ef3 UDP-GlcNac:betaGal beta-1; 3-N 774.5506 436 153.9485 O60625 N10cd3 vesicle-associated membrane p 2480.868 2680 584.39 P07948 A21ab7 v-yes-1 Yamaguchi sarcoma vira 512.646 443 170.1742 Q9P2N4 M10gh4 a disintegrin-like and metalloprot 159.7274 227 72.96867 P47895 C04ab2 aldehyde dehydrogenase 1 famil 1247.008 2370 146.6644 P04233 G09ef1 CD74 antigen (invariant polypept 229.4566 174 86.99566 Q9NZ31 L12gh4 chromosome 20 open reading fra 345.4771 375 137.4415 O96002 G07cd5 chromosome × open reading frar 401.521 375 130.7318 O94907 J15gh6 dickkopf homolog 1 (Xenopus la 150.3215 200 84.53571 Q92796 K06ef5 discs; large (Drosophila) homolo 161.9581 154 84.90819 Q13115 O17ab4 dual specificity phosphatase 4 533.5415 730 146.312 P29317 F02ef5 EphA2 267.722 279 82.15254 P29323 D10ef5 EphB2 269.1596 232 74.35016 Q9UKF9 H10cd7 ets homologous factor 603.0262 587 102.0333 Q9NPD3 P22gh2 exosome component Rrp41 273.527 300 49.72784 O43524 G12ab4 forkhead box O3A 262.2734 169 102.6435 P21217 M16ab3 fucosyltransferase 3 (galactoside 189.3354 257 60.24803 O75205 D24ef2 G protein-coupled receptor; famil 621.7284 382 90.93956 O75712 A03ef1 gap junction protein; beta 3; 31 k 235.3139 402 145.5466 Q92908 D12ab4 GATA binding protein 6 293.117 199 93.59788 O95210 P05cd4 genethonin 1 331.9855 241 112.69 O95395 K21cd5 glucosaminyl (N-acetyl) transfera 297.4236 274 45.82301 P48506 F22ab5 glutamate-cysteine ligase; cataly 299.1944 243 134.9982 Q9UI98 F08ef8 hqp0256 protein 357.587 336 106.803 Q9H6D8 D18gh5 hypothetical protein FLJ22362 542.6184 595 127.4299 P05362 I02ab6 intercellular adhesion molecule 1 411.0131 424 67.80016 Q07627 J20gh7 keratin associated protein 1.1 288.3566 303 40.28571 Q9BYQ7 D10gh8 keratin associated protein 4.10 493.4934 605 96.51137 O75071 F15gh1 KIAA0494 gene product 240.2512 167 91.77931 Q9UPQ2 G22ef8 KIAA1100 protein 224.7248 349 135.6811 O43896 H10cd6 kinesin family member 1C 159.6982 170 73.44924 Q13887 L05ab5 Kruppel-like factor 5 (intestinal) 494.1259 376 97.43054 O00312 D22cd3 MAP kinase-interacting serine/th 147.9629 150 86.60695 O15264 H07ab8 mitogen-activated protein kinase 213.7425 160 76.32069 Q9UHA4 P10gh1 mitogen-activated protein kinase 268.8101 244 72.50042 P21397 F23ef6 monoamine oxidase A 427.3495 480 30.42645 P55196 N07ab7 myeloid/lymphoid or mixed-linea 164.9238 168 78.62952 Q12965 I24ab7 myosin IE 212.4935 276 122.0015 Q9HBW1 O10gh7 NAG14 protein 417.9837 396 86.84398 Q9H2W4 D20gh6 neural precursor cell expressed; 361.6431 463 75.41197 Q9NRR3 O06gh4 non-kinase CDc42 effector protei 194.8075 327 117.0936 P23511 M19ab8 nuclear transcription factor Y; al 239.2485 226 132.3351 Q99650 D14cd4 oncostatin M receptor 337.1614 233 141.0848 P04085 O16ef7 platelet-derived growth factor alp 441.7554 463 124.4793 Q13048 N06cd2 pregnancy specific beta-1-glycop 149.7737 203 84.53571 P10586 E11ef6 protein tyrosine phosphatase; re 466.2876 405 136.6718 O95200 N22ab8 retinoic acid receptor responder 437.2899 315 72.62859 Q9NVX8 P17ef3 Rho GTPase activating protein 8 425.2848 479 109.2541 Q15418 N14ef5 ribosomal protein S6 kinase; 90 k 299.528 361 78.38666 Q15434 F10ab8 RNA binding motif; single strand 454.6438 328 145.2438 Q15437 O10cd6 Sec23 homolog B (S. cerevisiae) 261.2005 235 126.9582 O60679 D15ef5 serum-inducible kinase 202.0368 194 62.20916 Q12890 N06ef5 SFRS protein kinase 1 350.4057 278 113.0428 Q12971 L03cd6 sialyltransferase 247.3141 329 96.91002 P78556 M02cd2 small inducible cytokine subfamil 308.0437 382 59.31325 O75751 F14ef4 solute carrier family 22 (extraneu 164.6419 238 66.83593 Q9UM01 D08cd4 solute carrier family 7 (cationic a 201.657 260 55.89528 Q9Y5X1 D10ef2 sorting nexin 9 219.1839 240 108.9101 P08842 D19ab3 steroid sulfatase (microsomal); a 436.4255 414 136.2997 O43760 G09cd5 synaptogyrin 2 391.0545 238 118.1167 O75674 N15cd5 target of myb1-like 1 (chicken) 276.5234 285 54.32353 P01135 K04ef7 transforming growth factor; alpha 215.9023 160 59.63082 Q9NT70 K13gh3 transmembrane protein vezatin 365.9385 401 129.2607 O60656 G13gh3 UDP glycosyltransferase 1 family 546.3937 438 27.51254 Q9NZ42 N18gh4 uncharacterized hematopoietic s 196.9377 213 115.2737 O76080 E14cd4 zinc finger protein 216 314.9706 211 74.56541 Q13015 H11ab2 ALL1-fused gene from chromoso 329.6061 1730 1752.9 P04083 I06ab2 annexin A1 1114.486 8240 8292.245 O60592 B14ab2 Arg/Abl-interacting protein ArgBF 1576.114 3320 2017.836 Q07814 E04ef6 BCL2-associated × protein 430.8903 862 1101.457 Q14201 E17cd7 BTG family; member 3 197.8608 451 419.4378 Q9NR00 J21gh4 chromosome 8 open reading fra 2766.931 7310 3283.111 Q9BUW7 K19gh6 chromosome 9 open reading fra 228.4878 650 551.4272 O95401 N04cd4 cofactor required for Sp1 transcri 186.3494 395 588.6133 Q00535 B09ef5 cyclin-dependent kinase 5 269.7495 476 432.1176 P21741 E17ab7 midkine (neurite growth-promotin 2991.463 15400 9802.656 Q9Y291 J15ef2 mitochondrial ribosomal protein 177.4689 330 365.4484 O75376 E17cd6 nuclear receptor co-repressor 1 375.3679 1270 727.3836 P03973 N10cd1 secretory leukocyte protease inhi 592.855 2070 4153.51 O15427 F06cd4 solute carrier family 16 (monocar 228.58 753 785.8975 P16949 D11ab7 stathmin 1/oncoprotein 18 728.2643 2630 1984.807 Q9NZ86 J08gh3 uncharacterized bone marrow p 311.3754 945 536.938 O00748 H07cd4 carboxylesterase 2 (intestine; live 1080.553 220 253.3623 Q13630 M01cd3 tissue specific transplantation an 622.3905 287 255.576 P00505 C14ab6 glutamic-oxaloacetic transamina 494.0876 356 260.2263 P50440 A09ab5 glycine amidinotransferase (L-ar 1737.906 395 261.2318 P29622 A06cd1 serine (or cysteine) proteinase in 461.3518 189 264.9574 O14646 C17ab4 chromodomain helicase DNA bin 867.7631 180 273.1703 P48307 I10cd4 tissue factor pathway inhibitor 2 920.3007 366 277.6619 Q15125 D08cd6 emopamil binding protein (sterol 897.4306 230 282.4317 P19387 B13ab8 polymerase (RNA) II (DNA direct 196.4282 155 282.8549 Q9P0K7 H08gh6 retinoic acid induced 14 177.983 275 283.8007 P30086 E04ab8 prostatic binding protein 634.2686 462 300.6211 Q13045 C06ab5 flightless I homolog (Drosophila) 622.7072 501 306.0777 O95084 G10cd7 protease; serince: 23 1096.756 246 314.746 P49770 L11ef4 eukaryotic translation initiation fa 731.6826 547 329.7361 Q13948 J02ef6 cut-like 1: CCAAT displacement 222.2758 349 330.5149 Q30201 H05ab3 hemochromatosis 205.1607 291 339.4607 P52895 I16gh6 aido-keto reductase family 1; me 4001.572 263 339.7988 Q9Y5N1 M24cd7 histamine receptor H3 526.5133 203 341.1301 P43378 N23ab8 protein tyrosine phosphatase; no 1360.729 445 368.4734 P35414 O11ab2 angiotensin receptor-like 1 620.7039 406 395.8948 Q14802 K03cd1 FXYD domain-containing ion tra 2174.215 711 402.87 Q9Y266 F16cd6 nuclear distribution gene C hom 745.3985 447 408.3037 P30043 O21ab3 biliverdin reductase B (flavin red 877.6813 565 417.1383 Q9NP73 L06gh3 uncharacterized hematopoietic s 804.2103 446 421.5183 Q12972 D17ab8 protein phosphatase 1; regulator 251.1796 358 425.52 Q9Y296 N21ef2 PTD009 protein 738.5086 424 436.6114 Q02750 K02ef7 mitogen-activated protein kinase 810.206 508 441.4249 P42226 G23cd2 signal transducer and activator 0 892.6025 516 450.4229 P31947 M07ef6 stratifin 2941.197 741 452.267 P46597 J12ab2 acetylserotonin O-methyltransfer 2225.944 437 466.9229 O14745 J24cd4 solute carrier family 9 (sodium/h 1844.719 642 504.4269 Q9NS67 D24gh1 G protein-coupled receptor 27 1464.475 381 595.0192 Q9UKL5 J07cd8 programmed cell death 6 interact 995.6375 886 605.9272 Q9UQL3 B11ef2 liver-specific bHLH-Zip transcript 825.7324 1150 606.7901 Q9NZZ1 P18ef2 hypothetical protein HSPC138 397.5554 450 618.4035 Q9Y3Q3 H03cd7 integral type I protein 526.2023 355 631.4284 Q9NSN3 C10gh4 similar to aspartate beta hydroxy 355.1305 273 667.4052 Q9Y5Z0 B12cd7 beta-site APP-cleaving enzyme 2 1469.687 960 680.3343 C21gh7 H2B histone family; member B 511.589 855 733.4035 O14713 M11cd5 integrin cytoplasmic domain-ass 446.3806 746 737.9643 P46095 P11ab4 G protein-coupled receptor 6 2336.841 460 760.4217 Q9BV10 K07gh6 hypothetical protein MGC3136 1761.627 653 779.7338 Q99653 O08cd7 calcium binding protein P22 1713.549 1430 793.2383 P41584 P16gh1 polymerase (RNA) II (DNA direct 560.1066 892 821.9856 P11940 E06ab8 poly(A) binding protein; cytoplas 1738.585 669 827.8343 Q00341 G21ab6 high density lipoprotein binding 545.5844 444 866.5328 Q16795 K08ab7 NADH dehydrogenase (ubiquino 1582.872 1190 873.0478 Q13082 E05ab7 microtubule-associated protein 4 1217.396 472 873.8683 P36405 D16ab2 ADP-ribosylation factor-like 3 508.3031 547 939.7264 Q9NXH2 C04gh2 hypothetical protein FLJ20254 515.6731 467 959.9781 Q9Y323 D21ef2 hypothetical protein HSPC177 838.9663 1630 976.2242 P48059 I12ab7 LIM and senescent cell antigen- 560.9674 918 1003.945 Q9P0M9 M02ef2 mitochondrial ribosomal protein 579.0083 936 1024.359 Q13813 E07cd2 spectrin; alpha; non-erythrocytic 2261.592 886 1070.984 Q9Y379 H07ef2 CGI-69 protein 2556.713 1900 1174.107 Q13247 O13gh1 splicing factor; arginine/serine-ri 718.1614 1210 1194.951 P14416 D03ef6 dopamine receptor D2 814.5351 745 1299.03 Q06323 A15ef7 proteasome (prosome; macropai 1491.803 2350 1386.719 Q9NR31 H17gh4 SAR1 protein 752.6343 886 1386.849 P05451 C07cd3 regenerating islet-derived 1 alph 75644.12 1690 1394.425 P04075 C12ab2 aldolase A; fructose-bisphosphat 4534.199 1590 1470.967 Q15904 A19ab3 ATPase; H+ transporting; lysoso 833.0193 1380 1471.799 P15559 G24ef7 NAD(P)H dehydrogenase; quino 537.0892 303 1486.45 O00303 L20cd3 eukaryotic translation initiation fa 1243.805 636 1556.448 P56705 M01gh7 wingless-type MMTV integration 3589.752 1590 1635.805 P39210 I04ef7 MpV17 transgene; murine homo 990.336 894 1723.06 Q9UKL9 N03ef4 aldo-keto reductase family 1; me 16311.31 2840 1896.102 O43516 E12cd3 Wiskott-Aldrich syndrome protein 1162.511 1190 1979.246 Q9Y470 D01ef7 stem cell growth factor; lymphoc 1346.693 1110 2049.542 P29312 H12cd4 tyrosine 3-monooxygenase/trypt 5187.766 4710 2331.854 Q9Y5R8 P24gh4 MUM2 protein 1596.032 1750 2568.113 P17676 D01ab5 CCAAT/enhancer binding protein 6064.068 2880 2723.688 O95362 F11gh6 differentially expressed in hemat 10407.52 2680 2912.158 O60417 C11gh7 S100 calcium binding protein A1 6955.642 5690 3097.579 P19623 E17cd2 spermidine synthase 1644.266 1020 3417.978 Q9P039 P02ef7 FXYD domain-containing ion tra 2410.08 2120 4486.029 Q9BUF5 F05gh8 tubulin beta-5 2252.623 1580 4730.755 P00995 C23cd2 serine protease inhibitor; Kazal 67989.21 11300 5416.175 P11142 E22ef7 heat shock 70 kD protein 8 11154.99 7840 5433.843 P10620 E16ef7 microsomal glutathione S-transfe 6706.736 2430 5571.411 Q13347 N02cd3 eukaryotic translation initiation fa 19633.03 5210 5660.757 P15880 B16cd1 ribosomal protein S2 4356.01 2060 5964.993 Q9HCU0 E24gh4 tumor endothelial marker 1 prec 3139.145 2600 7148.075 Q04941 O16ab8 proteolipid protein 2 (colonic epit 17951.73 11800 8567.736 Q9UPI1 M14cd2 small nuclear ribonucleoprotein 4625.515 8280 8998.787 P13987 B18ef7 CD59 antigen p18-20 (antigen id 17383.17 19200 10453.43 P15951 N04cd2 protease; serine; 3 (trypsin 3) 74972.46 7610 11417.5 P04687 P12cd1 tubulin; alpha; ubiquitous 15943.82 7260 15413.44 P04687 H12cd1 tubulin; alpha; ubiquitous 15832.93 7590 24085.35 Q9UI09 L02gh4 13 kDa differentiation-associated 1754.698 1990 2889.148 Q9Y6H1 E23ef2 16.7 Kd protein 5687.333 4050 5837.94 Q9P0U1 C07gh3 6.2 kd protein 2323.402 1990 3847.586 P80095 N10ab7 6-pyruvoyl-tetrahydropterin synt 3223.922 2620 1569.69 Q92747 F04ab2 actin related protein 2/3 complex 4894.401 3990 3030.018 O15144 F08ab2 actin related protein 2/3 complex 13976.76 21400 17206.31 O15145 F10ab2 actin related protein 2/3 complex 3065.881 3190 1793.813 P02570 A01cd7 actin; beta 66304.81 45400 38777.92 P02570 H12cd7 actin; beta 64949.74 42400 44598.66 P02570 P12cd7 actin; beta 21347.36 12200 15408.61 P02571 A06ab6 actin; gamma 1 69165.16 59100 65677.15 P12814 E23ab2 actinin; alpha 1 2400.607 2160 2638.011 O43707 G05ab2 actinin; alpha 4 6999.138 3810 3499.234 P53999 C05cd7 activated RNA polymerase II tran 4478.986 4320 6009.318 P18848 I03ef5 activating transcription factor 4 ( 7160.888 5420 7668.286 P53680 A07ef1 adaptor-related protein complex 2255.235 2530 4102.633 P29274 A18ef5 adenosine A2a receptor 1990.124 2960 2004.596 P54819 A04ab2 adenylate kinase 2 2997.607 2520 2851.739 Q01518 O18cd6 adenylyl cyclase-associated pro 6946.788 11000 7171.205 P32889 C03ef6 ADP-ribosylation factor 1 6040.796 7220 7907.02 P18085 P21ab2 ADP-ribosylation factor 4 4777.904 8880 8342.165 P26437 B02ab2 ADP-ribosylation factor 5 3739.477 4430 3984.845 Q9BZX4 L08gh6 AKAP-binding sperm protein rop 2345.455 2780 2500.118 P11766 K01ab2 alchocol dehydrogenase 5 (class 2220.156 1990 2854.318 P05067 N03ef6 amyloid beta (A4) precursor prot 2846.85 4180 3918.595 Q06481 K22ab2 amyloid beta (A4) precursor-like 2117.652 3230 2290.191 P07355 I12ab2 annexin A2 74767.39 112000 97217.17 P08758 I18ab2 annexin A5 4487.905 4270 7134.202 P55064 O08ab2 aquaporin 5 10851.57 14200 11650.24 Q13520 O10ab2 aquaporin 6; kidney specific 2404.748 2350 2457.278 P32391 D19ab2 ARP3 actin-related protein 3 ho 4291.823 4280 3941.05 O43776 E18ab7 asparaginyl-tRNA synthetase 2570.968 3010 2854.989 P24539 N22ab2 ATP synthase; H+ transporting; 2908.697 3800 3228.203 P48201 P04ab2 ATP synthase; H+ transporting; 5694.182 4370 4857.955 P05496 N24ab2 ATP synthase; H+ transporting; 2176.378 1760 2400.575 Q06055 P02ab2 ATP synthase; H+ transporting; 5784.579 3530 7732.552 O75947 P14ab2 ATP synthase; H+ transporting; 2668.028 2520 1881.974 P56385 P06ab2 ATP synthase; H+ transporting; 2682.798 2090 2616.726 P56134 P10ab2 ATP synthase; H+ transporting; 11587.91 17200 14181.18 P18859 P08ab2 ATP synthase; H+ transporting; 3879.939 4840 5176.585 O75964 P16ab2 ATP synthase; H+ transporting; 2021.591 2630 2009.026 P25705 N14ab2 ATP synthase; H+ transporting; 3657.512 2410 2967.207 P06576 N16ab2 ATP synthase; H+ transporting; 4072.978 3280 2557.962 P36542 N18ab2 ATP synthase; H+ transporting; 2479.5 2030 2436.284 P48047 P18ab2 ATP synthase; H+ transporting; 4222.314 4100 3541.047 Q01814 P01ef5 ATPase; Ca++ transporting; plas 3157.447 3180 3242.707 Q99437 A11ab3 ATPase; H+ transporting; lysoso 2495.618 3870 2087.291 P36543 A09ab3 ATPase; H+ transporting; lysoso 1854.198 2920 1659.749 O75348 A15ab3 ATPase; H+ transporting; lysoso 2734.484 5660 2721.878 Q16864 A21ab3 ATPase; H+ transporting; lysoso 6452.29 15900 7960.234 P27449 A05ab3 ATPase; H+ transporting; lysoso 17134.14 24300 13120.57 O00244 L14ab2 ATX1 antioxidant protein 1 homo 2833.957 3500 3977.547 O14503 M19ab3 basic helix-loop-helix domain co 4978.916 4280 3254.631 O60238 L11ab5 BCL2/adenovirus E1B 19 kD inte 1473.428 2420 3224.141 P30536 L21ab3 benzodiazapine receptor (periph 1997.929 2890 2326.211 P01884 C23ab3 beta-2-microglobulin 64872 105000 36055.95 P22004 I13ab5 bone morphogenetic protein 6 5036.985 4710 3780.005 O95415 B02ef3 brain protein I3 7498.734 11200 5348.84 O75531 K11ab3 Breakpoint cluster region protein 2541.789 2740 2924.826 P02593 A10ab6 calmodulin 2 (phosphorylase kin 1573.77 4130 4742.485 P07384 O24ef1 calpain 1; (mu/l) large subunit 3429.132 3420 2390.011 P27797 P05ab5 calreticulin 10259.42 9700 15437.35 N06gh8 CaM-KII inhibitory protein 20298.71 28200 21760.79 P47756 N14ab4 capping protein (actin filament) n 4348.079 4450 5015.377 P15086 H13ab5 carboxypeptidase B1 (tissue) 9766.062 27.1 26.97129 P52952 D22ab5 cardiac-specific homeo box 2859.197 1740 2282.546 P13862 M21ef1 casein kinase 2; beta polypeptid 3674.921 3840 3873.228 O14675 I02ef6 CASP8 and FADD-like apoptosis 2622.586 2500 1151.661 P35221 C17ef7 catenin (cadherin-associated pro 3813.516 4230 3300.738 P07858 E01ab5 cathepsin B 2480.797 3860 4485.422 P48509 K16ab4 CD151 antigen 7267.56 13700 8768.731 P25063 G22cd8 CD24 antigen (small cell lung ca 21319.27 18200 8278.973 P16070 O21ef1 CD44 antigen (homing function 16178.96 9640 5778.642 P08962 O18ab4 CD63 antigen (melanoma 1 anti 9354.914 11600 10016.29 O14519 K04ef5 CDK2-associated protein 1 4231.191 4180 4763.013 P25763 A12ab6 cell division cycle 42 (GTP bindi 4588.819 2840 2852.186 P49368 N17cd2 chaperonin containing TCP1; su 2356.627 2880 2222.361 P48643 H10ef4 chaperonin containing TCP1; su 2238.933 2330 1561.625 O00299 M19ab6 chloride intracellular channel 6811.55 7240 5727.121 Q9Y2Q7 N02cd8 chromosome 11 open reading fr 4087.361 3800 5946.259 P09496 F15ab5 clathrin; light polypeptide (Lca) 5758.632 9260 5849.641 O95832 L04gh1 claudin 1 3046.376 2450 918.0838 O95471 A13ef1 claudin 7 2888.819 3350 1520.977 P23528 M20ab5 cofillin 1 (non-musle) 16021.95 18700 14063.43 P16989 L08ef6 cold shock domain protein A 2942.723 2530 2069.184 P38936 O21ef5 cyclin-dependent kinase inhibitor 3643.18 4250 3437.076 Q9UII4 B14ef1 cyclin-E binding protein 1 26180.8 29800 39655.02 P04080 G16ab3 cystatin B (stefin B) 4312.168 5420 2370.13 P21291 J01ab5 cysteine and glycine-rich protein 2478.366 1710 2135.86 O00622 J15ef7 cysteine-rich; angiogenic inducer 2070.203 1620 2978.542 P13073 L19ab5 cytochrome c oxidase subunit IV 6219.628 8550 6571.848 P12074 K13gh1 cytochrome c oxidase subunit VI 3253.24 5800 4244.557 Q02221 E17ab6 cytochrome c oxidase subunit VI 2968.24 2820 4604.241 P14854 A20ab6 cytochrome c oxidase subunit VII 1991.91 2660 2380.795 P09669 E12ab6 cytochrome c oxidase subunit VI 2580.598 2090 1927.002 P14406 G02ab5 cytochrome c oxidase subunit VII 4846.713 4500 4245.478 O14548 G23cd5 cytochrome c oxidase subunit VII 2182.954 2450 3040.586 P24311 K17ab5 cytochrome c oxidase subunit VII 3224.558 5150 3801.752 P15954 P04ab5 cytochrome c oxidase subunit VII 12335.74 12200 9883.688 P10176 B10ab5 cytochrome c oxidase subunit VII 3019.162 1900 3329.281 O43293 K19ab4 death-associated protein kinase 2535.403 1850 2088.808 P46966 G14ef6 defender against cell death 1 7921.682 11200 9546.896 Q09753 G01ab6 defensin; beta 1 4071.982 7630 2153.638 P18282 F23ab2 destrin (actin depolymerizing fac 7729.126 7570 6083.408 P07108 H04gh1 diazepam binding inhibitor (GAB 2541.011 1730 2995.768 P31689 D18ab7 DnaJ (Hsp40) homolog; subfamil 2491.051 2930 1789.662 Q9Y5T4 I10cd8 DNAJ domain-containing 2324.933 2520 2397.896 Q9Y463 G15cd5 dual-specificity tyrosine-(Y)-phos 8211.965 6870 5987.39 Q9NP97 C02ef8 dynein light chain 2A 4080.949 4160 5365.928 Q15701 L08cd3 dynein; cytoplasmic; light polype 4492.679 5800 4332.161 P78545 O16ab4 E74-like factor 3 (ets domain tra 3781.196 2780 1455.944 O60869 A03cd4 endothelial differentiation-related 5515.692 5680 4090.527 Q14259 L06ab4 enhancer of rudimentary homolo 3593.608 3950 5175.131 P06733 C16ab4 enolase 1; (alpha) 12539.97 7460 9955.024 P22712 D11gh6 enolase 1; (alpha) 6900.857 4290 5016.695 P04720 O07ab6 eukaryotic translation elongation 36222.34 23200 23485.94 P26641 A10ab4 eukaryotic translation elongation 6863.565 6540 11607.61 P13639 I15ab5 eukaryotic translation elongation 4023.855 2310 3360.073 O15372 L24cd3 eukaryotic translation initiation fa 2870.027 1930 2391.869 O75821 L22cd3 eukaryotic translation initiation fa 3009.075 2670 3333.728 Q64252 L11ab6 eukaryotic translation initiation fa 2755.438 1540 2127.874 O15371 L18cd3 eukaryotic translation initiation fa 4273.919 4030 3558.838 P04765 A22ab4 eukaryotic translation initiation fa 7716.222 7170 6363.169 Q14240 H13ab4 eukaryotic translation initiation fa 2091.816 2190 2519.322 P10159 A18ab5 eukaryotic translation initiation fa 9023.244 5240 5651.752 Q9NQT4 H05gh4 exosome component Rrp46 2098.514 2590 2304.48 P02794 C12ab6 ferritin; heavy polypeptide 1 35912.81 48700 42075.22 P02792 M10ab3 ferritin; light polypeptide 44225.86 29600 17849.2 Q05472 B02ab4 Finkel-Biskis-Reilly murine sarco 10322.94 10400 9704.642 P20071 F08ab3 FK506 binding protein 1A (12 kD) 2741.389 1870 1414.969 P50395 J02ab4 GDP dissociation inhibitor 2 2287.713 1580 2291.27 P48507 E12ab5 glutamate-cysteine ligase; modif 154.1773 76.2 5937.375 P36969 D14ab5 glutathione peroxidase 4 (phosp 3397.2 4860 3108.036 P09211 L10ab3 glutathione S-transferase pi 6392.334 8670 4067.789 P04406 A01cd8 glyceraldehyde-3-phosphate deh 28809.37 38300 44655.67 P04406 H12cd8 glyceraldehyde-3-phosphate deh 37562.25 60200 57135.41 P04406 P12cd8 glyceraldehyde-3-phosphate deh 12053.5 14900 19061.62 P43304 H01ab3 glycerol-3-phosphate dehydroge 3450.634 2340 3276.264 P41250 F02ef7 glycyl-tRNA synthetase 4333.439 3630 6248.604 P04895 K17ef5 GNAS complex locus 7755.858 9290 9107.558 P24522 B03ef6 growth arrest and DNA-damage- 2792.429 6130 3396.736 Q92847 M24ab5 growth hormone secretagogue re 2827.902 2100 2597.123 P04901 B01ef1 guanine nucleotide binding prote 5734.337 7610 5853.112 P25388 E20cd6 guanine nucleotide binding prote 22430.28 15300 19055.7 P06351 G08ab6 H3 histone; family 3B (H3.3B) 2448.264 2770 2042.864 P04792 A16ef5 heat shock 27 kD protein 1 41952.14 34500 31970.86 P11021 H01ef1 heat shock 70 kD protein 5 (glucc 3226.183 1600 4101.742 P38646 O19ab7 heat shock 70 kD protein 9B (mor 2851.743 2180 2220.509 Q9UK76 J14ef1 hematological and neurological 26342.33 35400 41099.58 P09651 F12ab7 heterogeneous nuclear ribonucle 2522.253 1650 2524.082 Q9Y4J5 I23ef1 heterogeneous nuclear ribonucle 3825.912 2370 3770.457 P09429 F10ab7 high-mobility group (nonhistone 2534.273 1660 3502.047 P49773 M03ef6 histidine triad nucleotide binding 6025.978 7790 7379.267 Q92769 N05ab4 histone deacetylase 2 2454.324 2220 1789.508 P17693 F08ab7 HLA-G histocompatibility antigen 2048.009 2780 1844.177 P17483 C15gh2 homeo box B4 2892.488 3490 2902.69 Q9UL99 C01cd8 hyaluronoglucosaminidase 4 3623.461 2050 2189.656 Q9GZT3 L18gh7 hypothetical protein DC50 3343.922 3750 4298.676 Q9NWY5 O12gh2 hypothetical protein FLJ20533 3104.471 5460 6184.227 Q9UI30 P08ef2 hypothetical protein HSPC152 3000.217 4060 4396.862 Q9BQB6 P08gh5 hypothetical protein IMAGE3455 3599.509 5410 8687.307 Q9BWJ5 P18gh7 hypothetical protein MGC3133 2074.073 2520 2719.671 Q9Y683 N11ef2 hypothetical protein MGC8721 2425.475 2730 2939.253 Q16665 P01ef6 hypoxia-inducible factor 1; alpha 3544.753 2960 1526.935 O75353 G04ef6 immediate early response 3 4564.408 4690 3129.721 Q16270 J15ab6 insulin-like growth factor binding 6185.622 21800 18047.34 Q9Y287 A03gh2 integral membrane protein 2B 6908.997 10500 10014.47 P56537 D16ab6 integrin beta 4 binding protein 2594.316 3270 1568.747 P26006 D08ab6 integrin; alpha 3 (antigen CD49C 2669.777 2740 1339.712 P05556 G01ef7 integrin; beta 1 (fibronectin recep 6743.428 5390 6511.579 Q01628 C09gh7 interferon induced transmembra 14426.62 14800 8827.997 Q12905 C10ab7 interleukin enhancer binding fact 3045.484 2420 2596.915 Q13907 A24ab7 isopentenyl-diphosphate delta is 2958.139 1660 2475.365 P33947 K03cd7 KDEL (Lys-Asp-Glu-Leu) endopl 1667.246 1250 3924.993 P00338 D15ab7 lactate dehydrogenase A 44081.29 34500 42150.03 P08865 G21ef7 laminin receptor 1 (67 kD; riboso 8548.245 6070 9921.409 Q08380 D17ab7 lectin; galactoside-binding; solub 2294.491 2850 3014.02 O14949 F17ef3 low molecular mass ubiquinone- 2942.579 3550 3637.463 Q15012 F20ef4 lysosomal-associated protein tra 2815.002 4690 5453.634 P14174 J05ef7 macrophage migration inhibitory 5544.722 6700 6763.718 P49006 M05ef6 macrophage myristoylated alanir 5857.382 10400 8986.315 P30463 G10ab6 major histocompatibility complex; 2701.757 4890 2255.929 P10321 A01cd2 major histocompatibility complex; 8949.086 17000 10196.88 P10321 H12cd2 major histocompatibility complex; 7187.905 21600 11111.54 P10321 P12cd2 major histocompatibility complex; 13121.35 16800 11725.68 P13747 M24ab7 major histocompatibility complex; 2540.911 2790 2053.351 Q95HC0 P02gh6 major histocompatibility complex; 5067.294 4140 3295.115 P13640 D13gh6 metallothionein 1G 6180.376 4750 2940.683 P80297 D17gh6 metallothionein 1X 4881.982 5310 5233.749 P02795 L04ab7 metallothionein 2A 6620.235 7330 8067.274 O14880 E04ab7 microsomal glutathione S-transfe 5023.542 7940 4177.165 Q9NYZ2 M22ef2 mitochondrial solute carrier 2488.07 2850 2240.824 P26038 K05ab7 moesin 4260.51 4580 3801.298 O15329 O12ef1 mucin 6; gastric 5574.093 5950 6685.047 P16475 J02gh1 myosin; light polypeptide 6; alkal 48122.62 45200 48882.54 P19105 N03cd6 myosin; light polypeptide; regula 7920.873 8150 7228.401 Q9UK23 D06ef1 N-acetylglucosamine-1-phospho 1884.596 2680 2511.293 O15239 E22ab7 NADH dehydrogenase (ubiquino 2859.738 5440 3719.503 O00483 J02ab7 NADH dehydrogenase (ubiquino 5214.222 5540 9086.615 O75438 J04ab8 NADH dehydrogenase (ubiquino 1628.024 2170 2842.647 O95168 J08ab8 NADH dehydrogenase (ubiquino 2297.787 3270 2253.854 O95298 J12ab8 NADH dehydrogenase (ubiquino 1909.371 2840 2888.281 O43920 J18ab8 NADH dehydrogenase (ubiquino 6241.135 11500 8014.187 Q13765 H09ab7 nascent-polypeptide-associated 2800.535 3390 3897.956 Q15843 K13cd1 neural precursor cell expressed; 3449.484 4710 4139.56 Q9NX14 C01gh3 neuronal protein 17.3 3476.812 3150 5077.834 Q9Y2R6 F18gh6 NICE-3 protein 1763.974 2250 2329.521 Q15668 H13cd6 Niemann-Pick disease; type C2 1516.592 3640 2828.255 O14597 J21ef4 non-functional folate binding pro 2917.293 2170 3004.012 P15531 E02ef5 non-metastatic cells 1; protein (N 6653.515 6940 7836.897 P22392 L12cd2 non-metastatic cells 2; protein (N 4827.494 5680 4836.596 O00746 D04ef7 non-metastatic cells 4; protein e 2211.058 2270 4300.604 O75534 B01cd4 NRAS-related gene 3478.657 3510 2737.425 Q9H9A1 C24gh6 nuclear receptor co-repressor/H 5951.715 3290 2990.083 Q9NPE3 K15ef4 nucleolar protein family A; memb 3543.239 7130 3639.205 P54368 G10ef1 ornithine decarboxylase antizym 7212.068 6880 7782.339 Q9UH52 L23cd8 over-expressed breast tumor pro 2335.527 2320 1884.264 Q15070 A09cd1 oxidase (cytochrome c) assembly 2161.529 2500 1436.483 Q9H230 G14gh5 p53-induced protein PIGPC1 1823.554 3330 1443.914 O60356 M03cd8 p8 protein (candidate of metasta 1774.942 1940 2740.792 P78337 M22ab8 paired-like homeodomain transcr 15428.96 13300 14490.63 Q9C086 P20gh7 PAP-1 binding protein 2992.2 3610 5014.215 Q15165 D06ef6 paraoxonase 2 1325.972 3740 2122.119 P20962 N13ab8 parathymosin 2345.869 2330 3489.616 P23284 I17ab8 peptidylprolyl isomerase B (cyclo 5298.839 5860 8890.43 Q06830 E18ab8 peroxiredoxin 1 2973.862 2450 2056.112 P32119 G04ef7 peroxiredoxin 2 3141.718 3330 2921.471 P30048 N09ab2 peroxiredoxin 3 2420.936 2010 1671.796 Q13162 N07ab2 peroxiredoxin 4 2744.707 2080 3645.718 P30044 P15cd7 peroxiredoxin 5 2205.14 3820 1714.041 Q13492 B13cd4 phosphatidylinositol binding clat 2688.917 2690 1861.508 P08237 P02ab7 phosphofructokinase; muscle 2790.708 1980 2829.743 P00558 P06ab7 phosphoglycerate kinase 1 5186.346 5130 6341.68 P18669 K14ab6 phosphoglycerate mutase 1 (brai 1847.463 2730 2859.446 Q14801 B01cd8 phosphoprotein enriched in astrc 23286.56 17400 19729.36 O14832 A04cd1 phytanoyl-CoA hydroxylase (Ref 7333.104 7780 8341.917 P53801 L01ef1 pituitary tumor-transforming 1 int 4385.308 5330 4172.137 Q9HB21 E19gh5 pleckstrin homology domain-con 2318.08 3070 2907.381 Q15365 O09cd1 poly(rC) binding protein 1 4617.635 3130 3156.644 P52433 B17ab8 polymerase (RNA) II (DNA direct 2157.353 3780 3657.763 P52436 L16gh1 polymerase (RNA) II (DNA direct 2161.398 2600 2709.495 Q03052 B19ab8 POU domain; class 3; transcripti 3321.206 2650 2251.677 K20gh5 PP1201 protein 7127.293 6650 2688.636 P40425 G08ab8 pre-B-cell leukemia transcription 2817.191 2650 3413.81 Q99471 K06ab8 prefoldin 5 1827.777 2160 2837.334 Q9UHZ2 E21ef8 PRO1073 protein 1872.208 3140 1690.101 P07737 A21cd1 profilin 1 29650.38 48900 35394.8 Q92740 E03gh1 prosaposin (variant Gaucher dis 4235.232 5370 4268.459 P07478 N02cd2 protease; serine; 2 (trypsin 2) 77359.27 42600 51746.68 Q9UL46 N09ab8 proteasome (prosome; macropa 3682.153 4550 2712.172 P25786 L09ef7 proteasome (prosome; macropa 2270.079 2570 2265.763 P20618 J17ab8 proteasome (prosome; macropa 2835.653 3590 2820.916 P49720 J21ab8 proteasome (prosome; macropa 1714.767 2100 2435.426 P28070 J23ab8 proteasome (prosome; macropa 2193.138 1760 2224.325 Q99436 L03ab8 proteasome (prosome; macropa 4179.694 3450 3072.098 P08129 G01ef6 protein phosphatase 1; catalytic 2543.089 2200 2276.462 O15355 D07ab8 protein phosphatase 1G (former 5896.408 4200 3717.85 P30153 A06ef3 protein phosphatase 2 (formerly 3858.567 4100 2765.011 Q15249 H13ef5 prothymosin; alpha (gene seque 11382.44 14500 9974.587 Q9NQ11 G03gh7 putative ATPase 2774.724 2460 2271.593 P41567 N06cd5 putative translation initiation fact 7487.872 6600 8909.545 Q15181 L18gh1 pyrophosphatase (inorganic) 4914.897 4350 2667.605 P14786 M24ab8 pyruvate kinase; muscle 6305.222 8060 9000.504 P57735 G12gh4 RAB25; member RAS oncogene 3343.628 4890 1366.379 P54725 E21cd1 RAD23 homolog A (S. cerevisiae 2533.36 1790 1753.113 P54727 M10ef6 RAD23 homolog B (S. cerevisiae 4038.864 5410 4983.21 O00538 P16cd5 RAS guanyl releasing protein 2 ( 2418.688 2310 1906.199 P06749 C21gh1 ras homolog gene family; memb 2136.708 1940 3003.841 P08134 B16ab2 ras homolog gene family; memb 4404.567 4490 2930.236 P06gh8 ras-like protein VTS58635 5451.542 6580 9066.798 P15154 C01ef6 ras-related C3 botulinum toxin s 10849.13 9720 10044.19 Q15347 B20cd6 Ras-related GTP-binding protein 1728.963 2380 2623.418 O95197 A06cd6 reticulon 3 3712.756 3420 3833.411 P09455 F12ab8 retinol binding protein 1; cellular 2211.12 4480 2383.274 P52565 K13ef6 Rho GDP dissociation inhibitor ( 3166.04 3200 3141.434 P27635 N19cd2 ribosomal protein L10 13406.29 7100 11103.69 P53025 G22cd1 ribosomal protein L10a 19374.73 15100 19939.26 P39026 D07cd1 ribosomal protein L11 14172.29 6760 10346.92 P30050 D09cd1 ribosomal protein L12 38376.69 24500 38669.34 P40429 A01ef1 ribosomal protein L13a 23800.5 22200 28159.37 P50914 B18cd4 ribosomal protein L14 18507.36 14600 16108.18 P39030 C13cd3 ribosomal protein L15 8407.532 8100 10809.12 P18621 D19cd1 ribosomal protein L17 8779.141 8440 10004.78 Q07020 D13cd1 ribosomal protein L18 12168.43 10200 15619.17 Q02543 C15gh1 ribosomal protein L18a 24976.59 27200 28170.19 P14118 D15cd1 ribosomal protein L19 6226.589 5530 5535.643 P46778 A13cd3 ribosomal protein L21 11156.59 11800 16742.21 P35268 D17cd1 ribosomal protein L22 16289.45 16200 18991.35 P23131 F11cd4 ribosomal protein L23 20972.93 20400 25729.93 P29316 G09cd3 ribosomal protein L23a 6385.675 4840 5446.963 P38663 D21cd1 ribosomal protein L24 7805.803 6180 5479.195 P08526 F01cd1 ribosomal protein L27 12874.22 5280 10256.69 P46776 F05cd1 ribosomal protein L27a 16046.37 17000 20949.85 P46779 F07cd1 ribosomal protein L28 40540.59 32400 45810.52 P47914 E23cd3 ribosomal protein L29 3346.473 1960 1947.028 P39023 B21cd1 ribosomal protein L3 13192.5 10500 13962.55 P04645 F03cd1 ribosomal protein L30 17693.61 12300 21530.83 P12947 F09cd1 ribosomal protein L31 9749.468 8980 12591.65 P02433 A15cd3 ribosomal protein L32 22774.44 24400 30742.77 P49207 F11cd1 ribosomal protein L34 13251.1 11500 13193.66 P42766 K16cd7 ribosomal protein L35 10454.27 10500 10655.65 P18077 F13cd1 ribosomal protein L35a 14583.91 10700 8811.726 P09896 J06gh1 ribosomal protein L36a 8395.644 8780 12052.18 P09896 A19cd3 ribosomal protein L36a-like 5167.775 5750 4693.401 P02403 F15cd1 ribosomal protein L37 31895.4 45000 41301.54 P12751 F17cd1 ribosomal protein L37a 18652.48 17300 19955.82 P23411 F19cd1 ribosomal protein L38 5149.82 5570 7560.21 P02404 A17cd3 ribosomal protein L39 14114.05 21300 22827.16 P36578 B23cd1 ribosomal protein L4 14367.47 10400 10448.85 P28751 L06gh1 ribosomal protein L41 35135.75 34300 40372.62 P46777 E21cd3 ribosomal protein L5 12002.66 8880 10351.69 Q02878 D01cd1 ribosomal protein L6 15861.7 7300 10119.01 P18124 D03cd1 ribosomal protein L7 21230.67 15900 19538.32 P11518 G11cd3 ribosomal protein L7a 13385.5 8240 10586.53 P25120 D05cd1 ribosomal protein L8 23580.43 18300 24766.14 P32969 B19cd1 ribosomal protein L9 28853.42 32200 37288.41 P46783 H13cd1 ribosomal protein S10 7453.342 7660 7511.766 P04643 H15cd1 ribosomal protein S11 13429.85 15600 13623.52 P25398 H17cd1 ribosomal protein S12 16170.73 10600 12294.27 Q02546 H19cd1 ribosomal protein S13 13956.88 12600 15289.54 P11174 H21cd1 ribosomal protein S15 21322.73 19600 23334.6 P39027 H23cd1 ribosomal protein S15a 16787.1 15100 21854.01 P17008 J01cd1 ribosomal protein S16 26604.5 15700 24481.55 P08708 J03cd1 ribosomal protein S17 13979.25 7990 15360.88 P25232 A17gh2 ribosomal protein S18 12558.18 12600 20093.07 P17075 J07cd1 ribosomal protein S20 21944.13 19900 31381.43 P35265 D24ef7 ribosomal protein S21 14046.7 9470 9023.678 P39028 J09cd1 ribosomal protein S23 12228.98 10900 14550.17 P16632 J11cd1 ribosomal protein S24 12913.37 13100 12135.49 P25111 J13cd1 ribosomal protein S25 6274.159 5630 5123.747 P02383 C01cd3 ribosomal protein S26 26138.26 30900 19440.2 P42677 G01cd3 ribosomal protein S27 (metallop 17556.94 12800 20383.13 P14798 B18cd1 ribosomal protein S27a 3284.551 3180 2757.252 P25112 J15cd1 ribosomal protein S28 30384.24 32000 28529.21 P30054 J17cd1 ribosomal protein S29 18454.55 20900 25539.27 P23396 H03cd1 ribosomal protein S3 5913.682 2830 5523.561 P49241 O16ef5 ribosomal protein S3A 7154.088 6200 8592.248 P12750 A21cd3 ribosomal protein S4; X-linked 19821.56 16200 21778.05 P22090 A23cd3 ribosomal protein S4; Y-linked 2629.697 2330 2779.184 P46782 H05cd1 ribosomal protein S5 15421.08 11000 17355.54 P10660 H07cd1 ribosomal protein S6 46408.18 26100 40579.46 P23821 H09cd1 ribosomal protein S7 18906.94 16200 14326.88 P09058 H11cd1 ribosomal protein S8 15941.2 12300 20997.59 P46761 A01cd5 ribosomal protein S9 6215.562 3930 5714.843 P46781 H12cd5 ribosomal protein S9 8827.416 9710 15295.98 P46781 P12cd5 ribosomal protein S9 9059.523 1790 5725.082 P05387 H01cd1 ribosomal protein; large P2 16611.14 12700 17775.72 P05388 F21cd1 ribosomal protein; large; P0 17127.41 12400 19746.88 P05386 F23cd1 ribosomal protein; large; P1 2226.298 1880 3134.529 Q9Y254 C08ef3 ring-box 1 2597.578 4260 3365.165 Q9NWJ8 A23gh3 roundabout homolog 4; magic 1969.602 3940 2093.279 P08206 D06cd1 S100 calcium binding protein A1 38485.73 49800 31745.47 P31949 E09cd3 S100 calcium binding protein A1 8890.594 11100 5408.269 P06703 P17gh6 S100 calcium binding protein A6 3403.146 4070 2088.478 P55735 J04ef4 SEC 13-like 1 (S. cerevisiae) 1695.152 1990 2362.541 P38384 I06ef3 Sec61 gamma 5653.955 7820 7254.423 Q9NZJ3 H06ef2 selenoprotein T 2923.813 2440 1325.491 O15532 H16cd1 selenoprotein W; 1 2678.843 2970 3918.44 Q13501 J23cd4 sequestosome 1 3214.395 3170 1164.17 P35237 L18ab8 serine (or cysteine) proteinase in 4203.074 8180 2936.72 P05121 P05ef7 serine (or cysteine) proteinase in 4454.56 7280 9179.863 Q00587 C14cd7 serum constituent protein 2480.698 2660 2044.608 Q9H299 P16gh7 SH3 domain binding glutamic aci 14473.6 17100 13798.02 P37108 E21cd2 signal recognition particle 14 kD ( 24326.27 35600 24319.59 P49458 E19cd2 signal recognition particle 9 kD 1874.967 2640 3141.422 P43308 G15cd2 signal sequence receptor; beta ( 4209.147 4610 5876.451 P51571 O15gh1 signal sequence receptor; delta ( 2062.113 2330 2654.968 O00422 M17cd6 sin3-associated polypeptide; 18 k 2502.79 2610 2079.295 O75918 J10cd5 small EDRK-rich factor 2 5927.595 7010 7926.059 P13500 C15cd3 small inducible cytokine A2 (mon 17077.97 38100 8786.323 Q15356 A09cd2 small nuclear ribonucleoprotein 2743.428 2150 2819.855 P14648 A13cd2 small nuclear ribonucleoprotein 899.6242 2800 2362.597 P12236 G01ef1 solute carrier family 25 (mitochor 7384.066 4760 6176.034 Q00325 K22ab8 solute carrier family 25 (mitochor 5074.308 3750 3779.577 P32745 N01cd1 somatostatin receptor 3 4102.668 4170 4748.989 P30626 E13cd2 sorcin 1895.592 2790 2280.297 Q01826 F18ef6 special AT-rich sequence bindin 26449.32 41300 24225.61 P21673 D12cd1 spermidine/spermine N1-acetyl 8349.882 16500 6013.659 P34991 G05cd3 S-phase kinase-associated prote 3072.601 2990 2396.506 P23246 B09cd2 splicing factor proline/glutamine 2694.629 2460 3348.423 P35716 C07cd2 SRY (sex determining region Y)- 5019.988 4860 2125.089 P35713 E10ef4 SRY (sex determining region Y)- 2575.791 3100 2024.386 Q06945 C05cd2 SRY (sex determining region Y)- 2299.474 2210 1636.067 P00441 G20ef7 superoxide dismutase 1; soluble 4439.342 4930 3239.195 P50502 I18cd2 suppression of tumorigenicity 13 2307.599 2530 2358.117 Q9Y5Y6 P20gh1 suppression of tumorigenicity 14 2358.28 2700 1494.856 P17600 J06cd2 synapsin I 1969.157 2220 2010.908 O43759 G11cd5 synaptogyrin 1 14516.6 10700 10060.61 Q12962 P19cd2 TAF 10 RNA polymerase II; TATA 5937.255 5080 3962.323 Q15763 B20cd2 t-complex-associated-testis-expr 2022.997 2890 2885.017 P10599 B23cd4 thioredoxin 11525.16 11900 6440.37 P13472 O02ef7 thymosin; beta 10 46982.91 74300 54263.48 P01253 L12gh1 thymosin; beta 4; X chromosome 23145.54 26000 16231.51 Q01085 C02cd2 TIA1 cytotoxic granule-associate 2250.456 1770 2917.342 Q15370 J12cd2 transcription elongation factor B 2616.595 3980 3919.327 O43680 O11cd2 transcription factor 21 1789.295 1790 3044.118 P21980 O16cd2 transglutaminase 2 (C polypeptid 3131.079 3490 1857.596 P29401 N15cd1 transketolase (Wernicke-Korsak 3258.575 2040 2715.206 O60739 O01cd6 translation factor sui 1 homolog 2671.935 3400 3868.727 Q9NS69 I02gh7 translocase of outer mitochondri 2988.423 2450 3754.914 P00938 M24cd1 triosephosphate isomerase 1 5701.29 5820 8345.738 P07226 G10cd2 tropomyosin 4 2636.256 2300 3755.882 P04687 F09cd4 tubulin; alpha 3 20220.03 14500 22303.88 P04687 A01cd1 tubulin; alpha; ubiquitous 15258.81 7840 22478.65 Q13509 E04cd6 tubulin; beta; 4 2338.877 2990 1853.273 P04350 F01gh6 tubulin; beta; 5 7573.765 4430 3448.455 O75347 O08cd2 tubulin-specific chaperone a 3000.065 3900 3275.629 O75509 L10ef3 tumor necrosis factor receptor su 2245.338 4890 1881.231 P13693 G16cd2 tumor protein; translationally-con 39878.18 60800 48468.25 P14625 G24cd2 tumor rejection antigen (gp96) 1 2185.187 2060 4905.342 P42655 K04cd4 tyrosine 3-monooxygenase/trypt 6584.565 5730 5558.974 Q04917 G06cd3 tyrosine 3-monooxygenase/trypt 8621.322 8150 4562.366 P29312 A01cd4 tyrosine 3-monooxygenase/trypt 5873.282 4670 2279.148 P29312 P12cd4 tyrosine 3-monooxygenase/trypt 4562.964 1140 1520.2 O14957 G17cd7 ubiquinol-cytochrome c reductas 2728.765 3990 3332.422 P14793 D01cd4 ubiquitin A-52 residue ribosomal 3536.225 1730 3258.439 P02248 D22gh1 ubiquitin B 2753.942 4430 4152.235 O76069 B12cd4 ubiquitin-conjugating enzyme E2 2001.262 1980 2223.574 Q9BZL1 B17gh7 ubiquitin-like 5 4339.474 9100 5279.835 P08670 C24cd3 vimentin 5940.876 8720 17783.4 P45880 C18cd3 voltage-dependent anion channe 7005.537 7280 4758.179 Q9Y277 C04cd4 voltage-dependent anion channe 1863.424 2210 2573.885 P17861 O15cd4 X-box binding protein 1 3398.455 1600 2040.224 O43670 M04cd3 zinc finger protein 207 3338.117 3170 3176.631 Q07352 N21ef6 zinc finger protein 36; C3H type-I 6097.384 5750 4958.224 Q15942 M10cd3 zyxin 2570.21 2070 2519.748 Q16659 B17ef5 mitogen-activated protein kinase 144.6425 141 100.0111 O75324 B05cd3 stannin 131.7242 172 100.0655 Q9BYP8 E16gh8 keratin associated protein 17.1 176.4958 174 100.1011 P55291 J01ab4 cadherin 15; M-cadherin (myotut 158.7215 128 100.3297 P49768 L14ab7 presenilin 1 (Alzheimer disease 127.9653 124 100.3504 P55107 G10ab5 growth differentiation factor 10 114.7206 168 100.6326 P17082 P18cd7 related RAS viral (r-ras) oncoger 433.219 176 100.8465 P23634 N08ab2 ATPase; Ca++ transporting; plas 179.3836 276 100.9041 P78347 J20ab5 general transcription factor II; 151.6834 103 100.9514 P09912 F08ef7 interferon; alpha-inducible protein 183.6419 1050 101.0749 Q9H2F5 F13gh7 enhancer of polycomb 1 127.3938 115 101.3763 O14811 M06cd7 programmed cell death 10 152.3457 132 101.596 O60942 A17cd4 RNA guanylyltransferase and 5′- 176.7836 97.1 101.6765 Q9Y5Y3 M18cd7 G protein-coupled receptor 45 174.3335 161 101.8478 P11908 H15ab8 phosphoribosyl pyrophosphate s 166.1373 174 101.9334 Q92851 P18ab3 caspase 10; apoptosis-related cy 135.919 107 101.9435 Q9BQE5 M03gh7 apolipoprotein L; 2 109.8196 148 102.0533 P55327 D05cd2 tumor protein D52 136.2596 112 102.1111 P28332 K03ab2 alcohol dehydrogenase 6 (class 142.4055 97.7 102.1575 O95861 E02cd6 3′(2′); 5′-bisphosphate nucleotid 128.1251 116 102.1715 Q9NXJ5 A10gh2 hypothetical protein FLJ20208 122.4219 151 102.3038 Q15642 K09gh1 thyroid hormone receptor interac 120.9158 142 102.3082 O94997 O09cd7 decidual protein induced by prog 174.3087 140 102.3137 O95453 G02ab8 poly(A)-specific ribonuclease (de 139.9344 105 102.3217 Q9H9C5 F01gh7 KIAA1453 protein 135.8299 126 102.4347 P10451 B13cd1 secreted phosphoprotein 1 (oste 190.4604 76.7 102.5193 P53992 B03cd5 SEC24 related gene family; mem 134.307 105 102.5437 Q9NQW1 F22gh6 secretory pathway component S 111.3643 158 102.6234 Q01449 A17gh5 myosin light chain 2a 179.1031 170 103.0725 Q9NX46 K12gh2 hypothetical protein FLJ20446 109.5374 159 103.1083 P53609 A23cd1 protein geranylgeranyltransferas 140.0296 128 103.1248 Q15029 J16cd4 U5 snRNP-specific protein; 116 119.3284 126 103.1503 P50458 O23cd5 LIM homeobox protein 2 145.905 120 103.1971 P33764 B24cd1 S100 calcium binding protein A3 150.5991 204 103.3783 Q9P289 G03ef3 Mst3 and SOK1-related kinase 133.5225 116 103.4345 P52429 P17cd3 diacylglycerol kinase; epsilon (64 128.7238 123 103.5015 P54578 H17cd5 ubiquitin specific protease 14 (tR 160.7495 108 103.6864 Q13219 E24ab8 pregnancy-associated plasma p 112.9052 154 103.7948 O60547 M12ab5 GDP-mannose 4; 6-dehydratase 147.2805 108 103.8004 P23297 I17ef6 S100 calcium binding protein A1 145.2558 126 103.9033 Q9H5J8 M01gh6 hypothetical protein MGC5306 216.091 91.7 104.0432 Q14493 I08cd4 stem-loop (histone) binding prote 126.7755 155 104.1318 Q9NZU0 O16cd8 fibronectin leucine rich transmer 284.9107 268 104.3033 P80370 B01ef7 delta-like 1 homolog (Drosophila 160.1421 80 104.328 Q9NYV4 C23ef3 CDC2-related protein kinase 7 128.5947 107 104.3521 P09016 C23ef5 homeo box D4 173.2254 192 104.3556 Q13873 A16ab3 bone morphogenetic protein rec 155.8113 86.8 104.4206 O14878 B22ef4 inosine triphosphatase (nucleosi 124.8814 120 104.4238 P52848 J01ab6 N-deacetylase/N-sulfotransferas 166.2411 84.4 104.4555 Q14848 A05cd5 TNF receptor-associated factor 4 124.2461 136 104.4604 O00204 O04cd2 sulfotransferase family; cytosolic 185.8106 117 104.4824 P35610 E13gh1 sterol O-acyltransferase (acyl-Cc 143.8417 88 104.5518 Q04760 L03ab5 glyoxalase I 132.6871 107 104.5782 P51690 H06ab2 arylsulfatase E (chondrodysplasi 177.023 76.2 104.5865 P26012 C11ef7 integrin; beta 8 110.7396 170 104.6296 Q14978 K11cd5 nucleolar and coiled-body phosp 117.0048 131 104.685 O00764 D16cd3 pyridoxal (pyridoxine; vitamin B6 160.2678 140 104.6915 Q9Y6Q5 P13cd5 adaptor-related protein complex 149.3929 107 104.7705 O95350 G04cd5 Homer; neuronal immediate earl 137.2833 126 104.7829 P49748 C13ab2 acyl-Coenzyme A dehydrogenas 121.151 141 104.7897 P08100 O24cd1 rhodopsin (opsin 2; rod pigment) 125.3282 116 104.8101 Q15477 F24cd2 superkiller viralicidic activity 2-lik 102.5551 186 104.8138 O43520 I17cd1 ATPase; Class I; type 8B; memb 199.1157 91.5 104.8252 Q13039 P02ef4 ATP-binding cassette; sub-family 175.7841 80.5 104.8585 O15291 L12cd1 solute carrier family 7 (cationic a 276.3689 176 104.904 Q9NR71 L23gh4 mitochondrial ceramidase 108.9644 152 104.9361 O60884 H10cd4 DnaJ (Hsp40) homolog; subfamil 221.9835 239 104.9441 Q9BYE0 J17gh8 hairy and enhancer of split 7 (Dr 128.0255 108 104.9542 Q9Y272 L01ef2 RAS; dexamethasone-induced 1 101.2051 166 104.9825 Q9BUR5 M13gh6 hyphothetical protein MGC4825 78.2636 239 105.0137 O60859 A13cd7 neuropathy target esterase 123.9707 117 105.029 Q9GZU1 A20gh4 mucolipin 1 85.32301 243 105.1039 P19878 B15ab6 neutrophil cytosolic factor 2 (65k 310.5103 515 105.1041 Q13277 K12cd2 syntaxin 3A 118.5375 185 105.2511 B04gh8 reserved 130.849 124 105.2594 P32456 N18ab4 guanylate binding protein 2; inter 109.3786 142 105.2611 Q9H4M9 E01cd7 EH-domain containing 1 149.0051 151 105.3893 Q9BTX7 O19gh6 chromosome 20 open reading fr 115.9099 157 105.4128 Q9NVN2 M02gh3 solute carrier family 4 (anion exc 123.8178 114 105.466 Q99758 A17ab2 ATP-binding cassette; sub-family 238.456 145 105.5504 P43694 B06ef6 GATA binding protein 4 107.7539 161 105.5891 Q13825 C07ab3 AU RNA binding protein/enoyl-C 123.4494 140 105.6272 Q92550 L23ef3 ring finger protein 10 197.4603 112 105.7052 Q9UJS0 C12ef3 solute carrier family 25; member 119.1806 139 105.8216 Q99611 O05ef3 seleriophosphate synthetase 2 168.8742 128 105.8955 P17275 F08ab6 jun B proto-oncogene 135.9478 94.9 105.9141 Q13477 B09cd4 mucosal vascular addressin cell 127.8352 110 105.9239 Q14692 D09gh1 KIAA0187 gene product 114.5267 131 105.9487 P49908 D13cd2 selenoprotein P; plasma; 1 140.6083 104 105.9794 P54803 M24ab3 galactosylceramidase (Krabbe di 130.3854 105 105.9866 P50991 H09cd6 chaperonin containing TCP1; su 161.4396 148 106.0337 P35548 K11ab7 msh homeo box homolog 2 (Dro 182.4309 124 106.057 P11309 M14ab8 pim-1 oncogene 136.3951 99 106.0757 O75570 A03cd5 mitochondrial translational relea 128.9238 118 106.1208 Q9NY61 O01ef3 apoptosis antagonizing transcrip 120.3605 124 106.1404 Q9BTY8 D01gh7 hypothetical protein MGC4342 139.5304 92.9 106.2168 Q9NWS2 F09gh2 hypothetical protein FLJ20640 183.0823 140 106.2384 O00180 H06ab6 potassium channel; subfamily K; 129.4915 122 106.2703 O15382 I05ab3 branched chain aminotransferas 136.8391 95.5 106.3058 Q9Y2Z1 D05ef2 CGI-01 protein 156.4563 196 106.3369 Q9Y315 E18ef2 CGI-26 protein 135.7793 111 106.6662 Q9Y592 P20ef1 NY-REN-58 antigen 118.6541 121 106.7049 Q9NYT0 D20ef3 pleckstrin 2 (mouse) homolog 114.999 153 106.7508 Q9Y343 M10ef4 SBBI31 protein 123.0625 120 106.8362 Q9BVI4 G09gh6 hypothetical protein MGC3162 140.5988 123 106.8523 P30622 B20cd1 restin (Reed-Steinberg cell-expr 116.8074 136 107.0013 Q08345 F08ef5 discoidin domain receptor family; 266.6468 264 107.136 P33176 C16ab7 kinesin family member 5B 123.5679 113 107.2314 P55273 D14ab4 cyclin-dependent kinase inhibitor 99.64375 174 107.4234 Q9NW92 E10gh3 hypothetical protein FLJ10209 177.1237 168 107.454 Q9NZC3 K03ef3 membrane interacting protein of 105.8303 152 107.465 P15172 M19ab7 myogenic factor 3 132.7839 110 107.4694 P27144 A06ab2 adenylate kinase 3 118.5733 124 107.5998 O60508 A06ef2 pre-mRNA splicing factor 17 150.1968 130 107.6187 Q14012 B08cd3 calcium/calmodulin-dependent p 113.9231 135 107.6204 P98179 G12cd1 RNA binding motif protein 3 140.1356 93.2 107.7553 Q13223 E10ab5 BRF1 homolog; subunit of RNA 150.0469 115 107.7567 P55198 N09ab7 myeloid/lymphoid or mixed-linea 180.7113 122 107.7762 P46459 G02ef1 N-ethylmaleimide-sensitive facto 138.9363 95.7 107.8044 P34969 I21ef1 5-hydroxytryptamine (serotonin) 218.7666 181 107.8181 Q14667 K02gh1 KIAA0100 gene product 105.9471 222 107.8612 Q92830 J14cd8 GCN5 general control of amino- 129.4527 106 107.863 P14cd2 RNA binding motif protein; Y chr 112.3917 153 107.9125 O43252 J01cd5 3′-phosphoadenosine 5′-phosph 194.4946 188 107.9154 Q9NS93 G09ef3 seven transmembrane protein T 138.0932 237 107.9483 O60616 E20ab6 core-binding factor; runt domain; 489.0924 48.1 107.9969 P02261 D19cd4 H2A histone family; member C 145.0821 84.1 108.023 Q14701 F18ef7 DNA cross-link repair 1A (PSO2 119.2486 307 108.208 Q9P025 A04ef8 HSPC135 protein 160.3109 135 108.2493 P06702 O12ef7 S100 calcium binding protein A9 144.7319 163 108.2576 Q9Y5Q9 P05cd7 general transcription factor IIIC; 138.644 220 108.3524 P19075 O20cd2 transmembrane 4 superfamily m 129.5468 103 108.6355 O60905 B16cd4 sperm associated antigen 9 110.7683 139 108.6913 Q13322 F24ef5 growth factor receptor-bound pro 120.8593 115 108.7182 Q9UQ09 L01gh1 KIAA0470 gene product 190.3667 103 108.9005 P57053 J20gh6 H2B histone family; member S 113.6057 199 108.9238 Q92876 J03ab8 kallikrein 6 (neurosin; zyme) 197.2979 130 108.9308 P09960 F21ab6 leukotriene A4 hydrolase 96.36818 185 109.0526 Q9HBH1 O02gh5 peptide deformylase-like protein 138.0653 91 109.0612 P55082 L15ab7 microfibrillar-associated protein 121.4467 124 109.134 Q9NVH6 B01gh3 trimethyllysine hydroxylase; epsil 174.7559 81.6 109.1442 O95249 K10cd5 golgi SNAP receptor complex m 107.5878 143 109.1657 Q13891 M15ab6 basic transcription factor 3; like 2 126.6543 120 109.1942 Q9BZM5 H05gh7 UL16 binding protein 2 133.6731 245 109.2193 O94913 O20ef2 PCF11p homolog 205.6752 80.3 109.2409 Q12987 E03ef4 acidic 82 kDa protein mRNA 132.1136 117 109.4318 Q92499 D05ab5 DEAD/H (Asp-Glu-Ala-Asp/His) 176.6983 124 109.4356 Q13686 B19ab2 alkylation repair; alkB homolog 105.5169 143 109.4797 P43250 I08ab4 G protein-coupled receptor kinas 120.3579 113 109.4844 Q9UMX0 L03ef4 ubiquilin 1 122.0111 141 109.5522 O94905 G12cd7 chromosome 8 open reading fra 127.8659 107 109.6202 Q9UHK0 K01cd8 nuclear fragile X mental retardat 157.4757 87.6 109.6296 P25189 D01ab6 myelin protein zero (Charcot-Ma 110.5502 132 109.6859 Q10567 M11ab2 adaptor-related protein complex 208.9283 187 109.8204 O15230 D18cd8 laminin; alpha 5 111.864 141 109.8469 P52294 J10ab6 karyopherin alpha 1 (importin alc 178.7513 169 109.9831 O60668 M03cd2 TAF2 RNA polymerase II; TATA 123.6244 111 110.0571 P11688 J02cd1 surfactant; pulmonary-associate 136.0267 117 110.0847 Q9NWB6 P03gh2 hypothetical protein FLJ10154 174.7789 75 110.1306 Q9H028 E22gh8 histone deacetylase 10 107.5034 138 110.1585 Q9UMZ2 O22cd7 AP1 gamma subunit binding prot 120.2821 119 110.2219 P24752 C15ab2 acetyl-Coenzyme A acetyltransfe 216.1409 114 110.2562 P11230 B06ab3 cholinergic receptor; nicotinic; b 106.1774 151 110.2999 O14977 O18ef2 omithine decarboxylase antizym 119.9172 129 110.3 E15ef5 T cell receptor beta locus 139.7091 844 110.3287 P56937 N06ef2 hydroxysteroid (17-beta) dehydr 227.1137 74.5 110.3428 O75299 B21ab7 kinesin family member C3 113.15 128 110.3535 P16219 C09ab2 acyl-Coenzyme A dehydrogenas 109.4688 136 110.3636 Q9NZ48 J20gh3 uncharacterized hematopoietic s 112.5665 189 110.3995 Q9P163 L10gh4 hypothetical protein PRO2521 101.1317 159 110.4184 Q9BVT8 I07gh8 hypothetical protein MGC5442 135.5302 137 110.5044 Q99933 E02ef6 BCL2-associated athanogene 119.7332 115 110.533 O14645 M12cd3 dynein; axonemal; light intermed 164.1806 207 110.5493 Q9BRR9 E01gh8 Rho GTPase activating protein 9 120.3646 115 110.5606 Q9Y3E7 J19ef2 CGI-149 protein 158.4397 202 110.6074 P46976 C09ab6 glycogenin 127.6502 117 110.6815 O75928 C01cd5 Protein inhibitor of activated STA 98.84393 173 110.7286 Q9NX63 I18gh2 hypothetical protein FLJ20420 123.3725 159 110.8068 Q9UBS0 I20cd2 ribosomal protein S6 kinase; 70k 186.953 155 110.8188 Q15185 F18cd6 unactive progesterone receptor; 169.4269 72.3 110.8534 O60516 J18cd3 eukaryotic translation initiation fa 104.3739 147 110.9085 Q16651 J01ab8 protease; serine; B (prostasin) 334.0498 125 110.9253 P48788 E22cd2 troponin I; skeletal; fast 121.3602 110 110.9357 Q01968 N06ab7 oculocerebrorenal syndrome of L 169.0079 95.9 110.9507 Q9H6Z6 L11gh7 hypothetical protein FLJ21628 115.1546 126 111.0337 Q9NQ55 B01gh4 peter pan homolog (Drosophila) 122.449 120 111.0627 O95359 A24gh1 transforming; acidic coiled-coil α 108.2194 139 111.0999 P01189 I15ab8 proopiomelanocortin (adrenocort 145.0634 90.4 111.1389 Q9Y525 G13cd8 v-maf musculoaponeurotic fibros 119.023 141 111.1934 Q9UHC9 L09cd8 NPC1 (Niemann-Pick disease; ty 107.7403 138 111.3741 Q9HBT2 P14gh7 hypothetical protein PP1057 147.5097 98 111.4385 O00219 M22ef1 hyaluronan synthase 3 224.5087 89 111.4539 P22735 M16cd1 transglutaminase 1 (K polypeptid 136.8808 91 111.5589 O15388 A11ab4 sialic acid binding Ig-like lectin 6 105.2847 147 111.6016 O95389 J01cd4 WNT1 inducible signaling pathw 134.8825 94 111.6123 Q06190 D21ab8 protein phosphatase 2 (formerly: 134.6973 102 111.6192 P50226 C03cd3 sulfotransferase family; cytosolic 147.6874 101 111.8328 Q16632 N10ab5 general transcription factor IIIC; 120.7982 116 111.85 P54762 A24ef7 EphB1 107.3397 168 111.8669 Q15269 E15cd1 PWP2 periodic tryptophan protei 125.0688 107 111.8713 O14495 H10cd3 phosphatidic acid phosphatase 120.761 109 111.9087 Q9P0U0 N24ef3 PC326 protein 152.5639 101 111.9543 P50120 J02ab8 retinol binding protein 2; cellular 231.806 217 111.9639 Q9UHR0 D08gh1 G protein-coupled receptor kinas 111.83 151 111.9778 Q13977 A12ef1 cerebellar degeneration-related 105.2052 180 112.0477 P51692 C18cd8 signal transducer and activator o 126.7779 100 112.0645 P51164 N12ab2 ATPase; H+/K+ exchanging; bet 136.4695 112 112.2007 Q9NXH3 C02gh2 protein phosphatase 1; regulator 113.3081 127 112.2521 C04gh7 ER to nucleus signalling 2 112.9203 125 112.2701 P16435 G16ef6 P450 (cytochrome) oxidoreducta 110.2003 132 112.2899 E05gh6 hypothetical protein MGC5338 116.1511 137 112.3522 Q02080 L03ab7 MADS box transcription enhance 138.6124 100 112.3745 Q15334 J06ab7 lethal giant larvae homolog 1 (Dr 123.3076 110 112.3893 P10636 J13ab7 microtubule-associated protein 115.8818 142 112.4092 Q9Y4J6 A01gh2 zinc finger protein 6 (CMPX1) 138.8767 102 112.4376 Q9UHY7 P18gh4 E-1 enzyme 108.9217 134 112.5485 Q14147 K04gh1 DEAD/H (Asp-Glu-Ala-Asp-/His) 117.5358 119 112.7866 O95880 N06gh4 KIAA1513 protein 168.2097 104 112.9115 Q15013 J23ef3 gene predicted from cDNA with a 104.556 198 113.0807 Q9P1E2 E01gh4 hypothetical protein PRO2219 138.6039 107 113.1066 P07203 H23ef1 glutathione peroxidase 1 120.5127 114 113.1788 Q13206 M07ab5 DEAD/H (Asp-Glu-Ala-Asp/His) 140.5274 92.5 113.1804 O15085 L15ef3 Rho guanine nucleotide exchang 121.8405 111 113.2492 P48426 C07cd1 phosphatidylinositol-4-phosphate 232.9191 163 113.2533 Q9NRQ2 K20gh4 phospholipid scramblase 4 126.2397 116 113.2849 O43171 B24cd3 CDC14 cell division cycle 14 hon 126.784 113 113.382 Q9HB90 M02gh5 Rag C protein 132.9037 136 113.4299 Q9H733 I21gh5 single Ig IL-1R-related molecule 113.5449 137 113.4753 P43353 C06ab2 aldehyde dehydrogenase 3 famil 141.7651 101 113.5244 Q15053 G14gh1 KIAA0040 gene product 111.1705 146 113.5775 P22301 H01ef7 interleukin 10 174.8595 108 113.5877 Q9BW47 N12gh5 chromosome 20 open reading fr 125.8289 154 113.6231 P21917 M03ab6 dopamine receptor D4 158.6974 151 113.7899 Q9Y6K5 M19cd1 2′-5′-oligoadenylate synthetase 3 127.2648 142 113.9993 Q9Y2A4 N22cd5 Kruppel-type zinc finger (C2H2) 136.0849 133 114.1396 Q16880 A16cd3 UDP glycosyltransferase 8 (UDP 112.9309 133 114.1612 O95747 D09cd5 oxidative-stress responsive 1 113.39 123 114.2384 P25106 L12ef4 G protein-coupled receptor 100.7123 147 114.2482 H23ab6 immunoglobulin superfamily; me 102.6971 145 114.3219 P45984 L18ef5 mitogen-activated protein kinase 139.4168 88 114.3405 Q9NPF7 I03ef3 interleukin 23; alpha subunit p19 98.83593 182 114.4153 Q9UH94 L07cd8 prolactin regulatory element bind 140.4102 106 114.4158 Q16559 F05cd2 T-cell acute lymphocytic leukem 131.4974 111 114.5482 Q9UGH0 C02cd8 solute carrier family 17 (anion/su 98.73308 158 114.6616 Q15544 J13cd2 TAF11 RNA polymerase II; TATA 117.4634 123 114.6792 O00628 N24ab7 peroxisomal biogenesis factor 7 156.16 96.9 114.7281 O43241 F07ab5 golgi autoantigen; golgin subfam 123.9421 104 114.8381 Q9Y6N1 M14ab4 COX11 homolog; cytochrome c c 127.1203 100 114.8993 Q9UHX5 O01ef4 HT002 protein; hypertension-rela 98.26523 155 114.9242 Q01664 A02cd2 transcription factor AP-4 (activati 268.3453 66.7 115.0377 Q9BUI1 O03gh6 leukocyte receptor cluster (LRC) 112.2417 125 115.039 Q9HBL5 M17gh4 AD023 protein 103.9999 137 115.0443 Q9NXV2 N08gh2 hypothetical protein FLJ20040 126.6647 147 115.1386 Q15424 D08cd1 scaffold attachment factor B 134.9613 92.7 115.1845 P26440 F06ab6 isovaleryl Coenzyme A dehydrog 178.7093 115 115.2412 O60264 J11cd3 SWI/SNF related; matrix associa 105.7775 132 115.2498 Q15286 K07cd7 RAB35; member RAS oncogene 138.2766 183 115.3443 Q9UGK0 I10ef4 DIPB protein 303.2745 172 115.4096 Q92980 J06cd5 putative protein similar to nessy 142.089 181 115.4166 Q99726 M06cd3 solute carrier family 30 (zinc tran 112.8008 121 115.4854 P01111 O17ab8 neuroblastoma RAS viral (v-ras) 123.6283 108 115.5932 Q92574 G13cd3 tuberous scierosis 1 109.8519 128 115.7107 P16106 C01gh7 H3 histone family; member I 134.9364 118 115.868 Q9NWX5 O24gh2 hypothetical protein FLJ20548 118.1581 112 115.9919 Q9Y6B7 M05ab3 adaptor-related protein complex 217.8572 170 116.0173 Q9Y4F1 J04cd5 FERM; RhoGEF (ARHGEF) and 108.6215 130 116.0342 Q06710 M14cd3 paired box gene 8 120.1357 129 116.1006 Q9H6N1 J17gh5 hypothetical protein FLJ22056 214.4909 242 116.2509 Q9NSY1 K09gh3 homolog of mouse BMP-2 inducil 111.9034 123 116.2514 Q14106 H20cd6 transducer of ERBB2; 2 117.9634 134 116.2536 Q9UK11 B02ef4 zinc finger protein 223 119.1221 133 116.2873 P08069 O17ef6 insulin-like growth factor 1 recep 106.3434 178 116.3103 Q9H6F5 I21gh6 hypothetical protein MGC2574 120.5097 112 116.3129 Q14373 O04ab3 galactose-1-phosphate uridylyltr 157.7476 231 116.3555 P20393 G04ef5 nuclear receptor subfamily 1; gro 107.1138 138 116.4228 P36915 O01ab5 guanine nucleotide binding prote 120.9306 111 116.4819 O95109 G02cd8 chromosome 20 open reading fr 143.5726 103 116.5321 Q9NVS2 I24gh3 mitochondrial ribosomal protein 117.9573 124 116.6011 Q92950 B08cd6 CUG triplet repeat; RNA binding 109.8876 129 116.7366 Q14977 C04ab7 SP110 nuclear body protein 107.0969 158 116.8973 P16106 O04gh6 H3 histone family; member A 94.76745 159 116.9796 Q9Y3C1 N18ef2 hypothetical protein HSPC111 145.1935 164 117.0185 P37287 C11ef1 phosphatidylinositol glycan; clas 132.5354 109 117.2467 Q9UIG5 G05ef4 SEEK1 protein 102.5149 148 117.279 Q9UNE2 G15cd6 rabphilin 3A-like (without C2 dorr 110.3023 123 117.2874 Q14123 A17cd1 phosphodiesterase 1C; calmodul 121.3078 132 117.3754 Q16206 P03ab2 cytosolic ovarian carcinoma anti 116.5183 157 117.4492 Q9NWT1 D21gh2 hypothetical protein FLJ20624 116.0517 116 117.4816 Q12756 C05ab3 axonal transport of synaptic vesi 138.4398 232 117.5489 P28288 B10ab8 ATP-binding cassette; sub-family 140.4464 95.9 117.5959 P05198 G08ab5 eukaryotic translation initiation fa 115.5074 119 117.6033 Q9H0V9 D08gh7 hypothetical protein DKFZp564L 128.832 101 117.6689 Q92984 M10ef1 interferon-induced protein 35 258.0737 221 117.8182 O95498 A13cd5 vanin 2 109.7731 123 117.8273 Q9H1E1 J01gh8 ribonuclease 7 109.332 131 117.8377 Q9NV88 H01gh3 hypothetical protein FLJ10871 108.5849 125 117.8411 Q9Y310 F06cd6 SnRNP assembly defective 1 ho 119.9305 113 117.8563 P48382 O06cd1 regulatory factor X; 5 (influences 191.5142 122 118.0773 P52738 K04cd3 zinc finger protein 140 (clone pH 136.6586 154 118.1501 Q9NRW1 G23ef3 RAB6B; member RAS oncogene 100.578 179 118.1659 O15298 A02ab3 basic leucine zipper nuclear fact 266.9887 110 118.2062 Q9NUN5 D14gh3 hypothetical protein FLJ11240 114.5392 116 118.2691 Q07699 L03cd1 sodium channel; voltage-gated; 116.5431 113 118.3239 P27701 F10ab6 kangai 1 (suppression of tumorig 116.2761 108 118.3881 Q9UER5 O02ef3 TNF-induced protein 104.9755 131 118.4653 Q8TAC6 I24gh7 chromosome 11 open reading fr 117.4257 138 118.5887 Q9NRW9 K16gh4 angiotensin II; type I receptor-as 136.6357 105 118.6777 O95147 O15cd7 dual specificity phosphatase 14 181.9968 200 118.7007 Q13895 A19ef7 bystin-like 108.0232 124 118.7967 P31645 N03ef5 solute carrier family 6 (neurotran 114.6464 189 118.8487 P51511 N17ef7 matrix metalloproteinase 15 (me 122.9018 125 118.8609 Q15154 O11cd1 pericentriolar material 1 127.8378 139 118.8759 Q00007 E17ef6 protein phosphatase 2 (formerly; 108.364 123 118.9838 P55822 L08cd2 SH3 domain binding glutamic aci 131.7189 133 119.0263 Q14442 L20ab8 phosphatidylinositol glycan; clas 121.0635 114 119.0306 P54792 L04ab4 dishevelled; dsh homolog 1 (Dro 126.677 113 119.067 P42336 A03ef6 phosphoinositide-3-kinase; catal 101.0905 143 119.1581 Q9UMQ3 G15ab3 BarH-like homeobox 2 99.5713 179 119.1741 Q9UPY5 M04ef3 solute carrier family 7; (cationic 173.9407 69.5 119.3079 P19113 H01ef6 histidine decarboxylase 111.9277 119 119.3155 O95394 B16ef3 N-acetylglucosamine-phosphate 124.8164 112 119.3184 P22557 A14ab2 aminolevulinate; delta-; synthase 202.1179 129 119.3857 Q9Y3A2 G10ef2 CGI-94 protein 108.7497 167 119.4751 Q9H5J4 I05gh6 long-chain fatty-acyl elongase 135.0119 87 119.5181 P16083 E15ab8 NAD(P)H dehydrogenase; quino 154.7986 98.6 119.5724 Q99819 D02ab2 Rho GDP dissociation inhibitor ( 125.7962 106 119.5853 O75569 F06cd3 protein kinase; interferon-inducib 100.3086 137 119.6257 O15038 F12ef7 serine/arginine repetitive matrix 125.19 96.6 119.719 Q9HBH5 K09gh4 PAN2 protein 102.0601 139 119.7321 P41231 C22ab8 purinergic receptor P2Y; G-prote 131.9219 130 119.8105 O15397 D01cd6 RAN binding protein 8 114.6925 118 119.9197 Q9UDY8 C17cd7 mucosa associated lymphoid tiss 114.4769 120 119.9403 O95819 E22cd5 mitogen-activated protein kinase 92.42403 156 119.956 Q12999 J01ef5 sarcoma amplified sequence 114.9397 110 119.9579 P25440 D07cd2 bromodomain containing 2 116.6707 108 120.0152 P20827 H21ef7 ephrin-A1 298.0458 760 120.3333 Q9H652 P20gh8 hypothetical protein MGC4171 129.5733 107 120.4428 P31483 L20ef4 TIA1 cytotoxic granule-associate 105.4425 129 120.5386 Q9BSM8 G15gh8 hypothetical protein MGC10812 148.2279 273 120.573 P36897 F04ef5 transforming growth factor; beta 115.7567 108 120.6724 Q9UMR9 E08ef3 YME1-like 1 (S. cerevisiae) 256.0314 197 120.7227 Q92560 G11ab3 BRCA1 associated protein-1 (ubi 101.36 161 120.7575 Q9NWU1 D05gh2 hypothetical protein FLJ20604 99.76081 154 120.7609 Q92696 N14ab8 Rab geranylgeranyltransferase; 222.7157 272 120.7706 O95236 M24ef3 apolipoprotein L; 3 106.592 130 120.798 Q13202 E21ab5 dual specificity phosphatase 8 146.3963 129 120.7987 P11277 M02cd1 spectrin; beta; erythrocytic (inclu 112.72 114 120.8055 O95397 P18ef1 putative glycolipid transfer protei 99.78536 143 120.8708 P05423 A20ab3 BN51 (BHK21) temperature sens 131.8122 95.5 120.9201 Q14338 I17ab6 fucosyltransferase 2 (secretor st 99.71915 181 120.9483 Q9BYI8 A22gh8 AIE-75 binding protein protein 90.11911 164 121.0209 Q06203 D01ab8 phosphoribosyl pyrophosphate a 216.3154 105 121.029 Q9NZ33 P10gh4 brain expressed; X-linked 1 113.8613 162 121.0508 P04196 O10ab6 histidine-rich glycoprotein 116.1305 116 121.1163 O96029 F03cd7 opioid growth factor receptor 201.3579 93.5 121.2888 Q01196 I16ab5 runt-related transcription factor 1 441.1217 136 121.3316 Q9UHL4 J17cd8 dipeptidylpeptidase 7 180.3445 191 121.351 P55211 P16ab3 caspase 9; apoptosis-related cys 113.5416 111 121.3742 P21283 A07ab3 ATPase; H+ transporting; lysoso 288.6034 288 121.3828 O43422 P02ab8 protein-kinase; interferon-inducit 131.8635 100 121.394 P78406 L01cd3 RAE1 RNA export 1 homolog (S. 147.1192 97.1 121.4625 P43362 J18ab7 melanoma antigen; family A; 9 99.05783 139 121.5326 Q9H693 E12gh6 hypothetical protein FLJ22477 171.7699 96.4 121.6097 Q9UJ83 A11cd8 2-hydroxyphytanoyl-CoA lyase 99.45467 141 121.6399 Q05048 I15ab4 cleavage stimulation factor; 3′ pr 124.1609 105 121.6764 P19784 D11ab4 casein kinase 2; alpha prime pol 94.68573 152 121.7819 Q9BUX8 D06gh6 homolog of yeast ribosome biog 167.4752 178 121.8214 Q9Y5P6 D23cd8 GDP-mannose pyrophosphoryla 166.4572 89.4 121.8219 Q9Y3E1 F16af1 hepatoma-derived growth factor: 97.00713 148 121.9163 P40426 O07cd1 pre-B-cell leukemia transcription 122.6888 94.8 121.9253 P11217 K01cd1 phosphorylase; glycogen; muscl 314.8041 110 122.008 Q16563 D18cd2 synaptophysin-like protein 97.62823 144 122.0944 O95698 L07ab6 inhibitor of growth family; membe 102.2388 135 122.1358 P19447 K24ef6 excision repair cross-complemen 95.41189 148 122.1425 Q9UK39 D08cd7 CCR4 carbon catabolite repressi 173.8761 262 122.1589 Q15785 E23cd7 translocase of outer mitochondri 296.8521 144 122.1776 Q99571 C14ab8 purinergic receptor P2X; ligand- 418.1812 410 122.3053 Q9BTY2 E24gh8 hypothetical protein MGC1314 si 131.9449 91.5 122.3524 Q9P0P1 D12ef1 hypothetical protein FLJ10769 147.9172 191 122.4861 Q9Y324 P01ef1 CGI-35 protein 129.1118 97 122.5531 P37286 O17cd3 ubiquitin-conjugating enzyme E2 98.88763 165 122.5669 Q00577 O07ef5 purine-rich element binding prot 116.0341 123 122.5705 O75152 L21gh1 KIAA0663 gene product 101.4464 140 122.5789 P23610 H06cd7 coagulation factor VIII-associate 164.911 103 122.5902 O75436 M20cd5 vacuolar protein sorting 26 (yeas 118.1135 108 122.6522 Q9HA40 B23gh5 hypothetical protein FLJ12287 si 104.6286 126 122.666 Q9NX62 I20gh2 hypothetical protein FLJ20421 103.7764 136 122.701 O76062 E04cd2 transmembrane 7 superfamily m 301.1903 215 122.7645 Q16445 H02ab3 gamma-aminobutyric acid (GAB 150.641 87.5 122.7829 Q08462 G11ef6 adenylate cyclase 2 (brain) 107.541 146 122.8502 P78560 A22ef6 CASP2 and RIPK1 domain conta 108.4508 153 122.8627 P19634 N17ef5 solute carrier family 9 (sodium/h 118.9969 99 122.898 P28370 N12cd1 SWI/SNF related; matrix associa 115.471 106 122.9184 Q92503 H06cd1 SEC14-like 1 (S. cerevisiae) 151.5939 151 122.9424 Q9UL02 H24ef1 L-kynurenine/alpha-aminoadipat 105.6951 124 123.0487 Q9Y5T5 J13cd6 ubiquitin specific protease 16 117.1056 120 123.0646 G03gh8 protocadherin 15 153.0978 126 123.1548 P15848 H02ab2 arylsulfatase B 149.4791 95.6 123.1651 Q9UP66 P24ab6 low density lipoprotein receptor- 114.2435 124 123.2083 O75160 P07gh1 KIAA0672 gene product 121.9398 117 123.2554 P78385 L14ab6 keratin; hair; basic: 3 100.703 135 123.2569 O94967 B21ef8 KIAA0893 protein 92.15324 158 123.2707 O95719 K01cd5 xenotropic and polytropic retrovir 108.0877 122 123.3497 P48147 F09ab8 prolyl endopeptidase 130.0641 129 123.3564 P20231 B15gh7 tryptase beta 2 106.6865 130 123.4905 O95299 G02ab7 NADH dehydrogenase (ubiquino 107.385 129 123.5991 O75033 I18gh1 KIAA0445 gene product 121.5196 122 123.624 P51668 D03cd4 ubiquitin-conjugating enzyme E2 99.84401 137 123.637 P28289 E08cd2 tropomodulin 303.877 272 123.6484 Q15631 O12ef6 translin 173.134 152 123.6887 P49868 F03cd2 sulfotransferase; estrogen-prefer 122.2586 95.1 123.7564 P51959 O12ef5 cyclin G1 116.6841 102 123.7661 Q9Y5V0 J16ef1 HSPC038 protein 114.0123 179 123.7928 P56270 I12ef1 MYC-associated zinc finger prot 248.3395 140 123.8618 Q9HD23 O11gh4 MRS2-like; magnesium homeost 140.8864 117 123.8621 P78358 O03ab6 cancer/testis antigen 1 217.9167 137 123.9307 O00327 D24ab2 aryl hydrocarbon receptor nuclea 118.2008 185 123.9698 Q9H969 F08gh5 hypothetical protein FLJ12969 89.23821 177 124.0248 O15504 F01cd7 nucleoporin-like protein 1 200.4449 124 124.2046 P35250 I24ef8 replication factor C (activator 1); 111.3418 112 124.3534 Q9BXC0 F17gh8 G protein-coupled receptor 81 104.4833 128 124.3568 O15232 A19ef1 matrilin 3 113.1634 110 124.4317 O76049 L19cd5 spectrin SH3 domain binding pro 171.9625 299 124.5037 Q14145 C21cd8 Kelch-like ECH-associated protei 193.9671 120 124.5928 P20848 A10cd1 serine (or cysteine) proteinase in 97.77909 161 124.6004 Q9P0N6 C19ef3 hypothetical protein HSPC242 112.0065 109 124.6034 P05188 E12ab2 alkaline phosphatase; placental 88.50098 164 124.6125 Q9UBJ4 A01gh5 transposon-derived Buster1 tran 131.0923 97.3 124.7023 Q13876 I24ef7 quiescin Q6 144.3305 109 124.7205 Q9UBF2 F12cd7 coatomer protein complex; subur 110.1673 115 124.9117 P43026 I23cd3 growth differentiation factor 5 (ca 101.9864 152 124.9218 Q9HD20 E14gh4 CGI-152 protein 111.6731 134 124.9301 Q96KK6 P04ab8 RAB2; member RAS oncogene f 119.8171 106 124.9467 P40617 D18ab2 ADP-ribosylation factor-like 4 124.1402 143 125.0573 O75651 L12gh2 unc-93 homolog A (C. elegans) 131.989 128 125.0667 Q9Y2S1 L04ef1 galanin-related peptide 135.6724 134 125.067 Q13330 M20ef5 metastasis associated 1 104.9962 118 125.1131 Q9Y389 L22gh4 aminoadipate-semialdehyde deh 115.3352 104 125.222 O60513 I03gh1 UDP-Gal: betaGlcNAc beta 1; 4- 113.705 106 125.2504 O00212 C15ef6 ras homolog gene family; memb 407.7018 492 125.2682 Q9NXE1 J04gh2 membrane-associated nucleic ac 96.25484 146 125.3861 O95405 A16cd5 MAD; mothers against decapent 113.9303 223 125.3908 P01112 K12ab7 v-Ha-ras Harvey rat sarcoma vir 129.7326 104 125.3947 O15120 F11cd6 1-acylglycerol-3-phosphate O-ac 264.2959 238 125.4039 P12645 N10ab3 bone morphogenetic protein 3 (o 107.6548 117 125.4244 P50579 I01cd7 methionyl aminopeptidase 2 144.5853 95.1 125.4613 O14908 K01cd6 regulator of G-protein signalling 204.527 200 125.5241 Q9HCC6 I17gh4 bHLH factor Hes4 82.07855 213 125.5621 Q15737 E23gh1 suppressor of Ty 6 homolog (S. 112.2771 140 125.5917 Q9Y519 A17cd8 chromosome 22 open reading fra 100.4037 131 125.6586 Q9Y5J0 J01ef2 mitochondrial ribosomal protein 117.4353 107 125.8555 P51687 O16cd1 sulfite oxidase 105.2314 128 125.9497 P51178 A13ef6 phospholipase C; delta 1 126.4221 162 126.0345 Q9H8J6 H23gh5 NDRG family member 3 121.7115 198 126.048 O95900 B20ef8 hypothetical protein CLONE2492 165.6404 257 126.0637 Q9Y6N3 B01cd5 chloride channel; calcium activat 99.89597 135 126.1695 Q07869 C21cd1 peroxisome proliferative activate 120.1031 112 126.2127 Q9Y333 I07gh4 chromosome 6 open reading frar 109.0761 114 126.2563 Q9NPD1 L06gh2 G protein-coupled receptor 85 206.0578 285 126.2683 Q15928 K06cd3 zinc finger protein 141 (clone pH 101.1559 188 126.2732 O43826 I04ab4 glucose-6-phosphatase; transpo 229.7084 111 126.3113 Q9NWL0 J05gh2 hypothetical protein FLJ20758 114.0453 120 126.3891 P31629 B04ef6 human immunodeficiency virus t 116.0174 211 126.4284 O15530 I10ab8 3-phosphoinositide dependent p 186.1234 193 126.45 Q9Y2R5 L21ef4 mitochondrial ribosomal protein 106.3741 136 126.4713 Q15208 D01cd7 serine/threonine kinase 38 158.8765 204 126.5253 Q9UET6 J19gh6 FisJ homolog 1 (E. coli) 102.5266 120 126.5378 Q9H5N0 F15gh5 chromosome 7 open reading frar 102.3349 129 126.5687 Q9H019 B22gh4 hypothetical protein RP1-317E23 102.5329 150 126.5974 Q9Y673 F05cd8 A1g5; S. cerevisiae; homolog of 100.2543 131 126.6884 O75690 M08gh7 UHS KerB 121.3598 150 126.7819 Q9NUP6 H22gh2 hypothetical protein FLJ11220 95.908 144 126.8164 Q14296 C03cd7 FAST kinase 122.4924 92.9 126.9021 Q9NW55 B20gh2 hypothetical protein FLJ10307 94.73914 141 126.9877 O43639 H01cd3 NCK adaptor protein 2 139.9609 79.6 127.0293 P17544 L08ab2 activating transcription factor 7 108.5839 112 127.0848 O75911 M01cd5 short-chain dehydrogenase/redu 156.3658 173 127.1125 Q06430 K15ef3 glucosaminyl (N-acetyl) transfera 94.56995 139 127.1541 Q13769 D10cd3 chromosome 22 open reading fra 122.7812 121 127.1547 Q9H864 J14gh5 hypothetical protein FLJ11021 si 97.58044 142 127.1909 O95500 F06cd7 claudin 14 183.0294 181 127.2815 P14222 P02cd2 perforin 1 (pore forming protein) 99.11893 135 127.3674 Q9Y4C8 B06ef2 KIAA0682 gene product 105.4769 146 127.3803 Q9H3H5 M23ab4 dolichyl-phosphate (UDP-N-acet 193.8179 108 127.5134 Q13433 G05cd8 LIV-1 protein; estrogen regulate 118.096 105 127.6623 Q00059 O07cd2 transcription factor A; mitochond 111.4615 131 127.6629 Q15119 I06ab8 pyruvate dehydrogenase kinase; 97.01115 135 127.6675 O43791 F03cd3 speckle-type POZ protein 111.349 114 127.7061 Q14206 P10cd5 Down syndrome critical region g 119.8147 263 127.7164 Q92926 N24cd1 SWI/SNF related; matrix associa 115.147 105 127.7503 Q9P288 G15ef3 BRCA2 and CDKN1A interacting 148.9477 132 127.8623 Q9NZU5 C16ef4 LIM and cysteine-rich domains 1 164.1438 128 127.9349 Q13569 O13cd2 thymine-DNA glycosylase 83.16502 172 127.9545 P48167 D17ef6 glycine receptor; beta 109.5501 139 127.9738 Q9NQR1 I02gh4 PR/SET domain containing prote 154.2185 92.7 128.0258 O43405 B23ab4 coagulation factor C homolog; cc 103.0764 121 128.1793 Q9P028 N24ef2 CCR4-NOT transcription comple 104.0341 133 128.2089 Q9Y6E8 P04cd7 sirtuin silent mating type informa 109.1684 110 128.2444 Q9NV65 H17gh3 hypothetical protein FLJ10901 92.33747 188 128.3243 Q9H0R8 M13gh7 GABA(A) receptor-associated pr 122.091 179 128.3386 O95817 P02cd4 BCL2-associated athanogene 3 107.1752 114 128.4319 P36956 K10cd2 sterol regulatory element binding 140.2284 109 128.532 P08236 D05ab3 glucuronidase; beta 123.7102 114 128.6103 Q13425 D12cd2 syntrophin; beta 2 (dystrophin-as 106.7241 122 128.6723 Q14676 E18gh1 KIAA0170 gene product 93.41288 145 128.7328 P16106 O12gh6 H3 histone family; member F 98.02235 136 128.7695 Q14773 J03ab6 intercellular adhesion molecule 4 101.85 137 128.8098 O14736 N19gh4 putative methyltransferase 124.8741 126 128.8151 Q9Y297 N21cd4 beta-transducin repeat containin 152.2864 142 128.8641 Q13585 H16cd4 G protein-coupled receptor 50 121.9424 113 128.8853 O60858 L24cd5 ret finger protein 2 110.1643 110 128.8939 Q9Y2Z6 E06ef2 CGI-07 protein 96.22816 139 128.9272 Q9UG66 P16ef7 hypothetical protein DKFZp586G 318.3297 374 128.9795 Q9Y6G5 N17ef2 PTD002 protein 107.7937 141 129.1324 P98155 E06cd3 very low density lipoprotein rece 113.1365 104 129.1355 Q9NP50 C07gh5 TERA protein 94.63638 199 129.2792 P28328 C01ab8 peroxisomal membrane protein 3 321.6292 219 129.3474 Q969T4 M24cd6 ubiquitin-conjugating enzyme E2 117.2071 100 129.3512 P19827 D18ab6 inter-alpha (globulin) inhibitor; H 239.4455 186 129.3613 O15096 M18ab8 phosphatidylinositol 4-kinase; ca 117.2574 115 129.4365 Q9Y5J6 J16cd7 fracture callus 1 homolog (rat) 102.357 127 129.4503 Q92889 M24ab4 excision repair cross-complemen 157.5735 97.6 129.5255 P08697 C07ef1 serine (or cysteine) proteinase in 138.5253 136 129.5425 Q9UBX1 A05cd4 cathepsin F 113.4065 118 129.6557 Q9NPI7 D22ef1 hypothetical protein LOC51315 240.5378 171 129.76 P11586 D14ef7 methylenetetrahydrofolate dehyd 141.2456 106 129.8444 O96010 J15cd4 LIM domain binding 1 90.9506 155 129.8567 Q13188 P13cd2 serine/threonine kinase 3 (STE2 117.4664 135 129.8809 Q13845 I21ab3 B-cell CLL/lymphoma 7B 145.9359 88.3 129.9273 Q9Y5W9 D07cd8 sorting nexin 11 144.6605 198 130.0152 O60539 I02cd7 Ras association (RalGDS/AF-6) 126.8466 102 130.0346 O60885 I02ef3 bromodomain-containing 4 114.9928 98.1 130.1093 Q9H2B0 O16gh5 nucleosome assembly protein 1- 122.5782 147 130.1112 P51582 C24ab8 pyrimidinergic receptor P2Y; G-p 116.4263 109 130.158 O00585 F08cd1 small inducible cytokine subfamil 168.745 216 130.1849 Q15131 B23ef5 cyclin-dependent kinase (CDC2- 168.6104 108 130.2201 O75148 F08cd8 cryptochrome 2 (photolyase-like) 86.14249 172 130.27 Q15691 G17cd8 microtubule-associated protein; 173.7024 168 130.2758 Q15779 H21ab8 procollagen (type III) N-endopep 141.4408 133 130.2905 Q9UHD2 K14cd8 TANK-binding kinase 1 82.31867 172 130.2947 Q9NSS3 K15gh3 hypothetical protein DKFZp434E 107.5389 115 130.3095 Q13797 I01ef7 integrin; alpha 9 156.9946 85 130.4752 P46531 M10ef5 Notch homolog 1; translocation- 86.01963 164 130.4897 O43262 C01cd6 deleted in lymphocytic leukemia; 76.79463 195 130.4943 Q9Y2H6 k12ef8 KIAA0970 protein 170.8655 128 130.5238 P25788 J11ab8 proteasome (prosome; macropah 258.6025 285 130.5899 Q9BQS8 D09gh7 FYVE and coiled-coil domain co 164.6348 207 130.6451 Q9Y396 J04ef1 elongation of very long chain fatt 162.6431 82.2 130.6722 Q9P0R7 K06ef2 hypothetical protein LOC51242 126.7302 218 130.6804 O15269 F17cd6 serine palmitoyltransferase; long 97.42808 133 130.7429 Q9UFX0 B02ef2 calcium binding atopy-related au 233.5089 287 130.8943 Q9H663 F24gh5 likely ortholog of mouse actin-rel 98.1679 128 130.9258 O75410 P17cd2 transforming; acidic coiled-coil cc 224.1188 133 130.9827 Q9Y5N5 I14cd8 putative N6-DNA-methyltransfera 99.34841 133 131.0924 Q9BQ72 F02gh7 hypothetical protein MGC10471 106.3824 115 131.1126 Q9Y303 E10ef2 CGI-14 protein 153.5787 101 131.2035 Q9P005 A22ef8 HSPC159 protein 341.3083 579 131.3146 Q9Y3A1 H19ef2 DKFZP566O084 protein 200.4927 262 131.514 Q15172 C12cd1 protein phosphatase 2; regulator 168.3914 140 131.5524 Q9BV19 I19gh6 hypothetical protein MGC955 96.47316 141 131.6188 Q14534 E11cd2 squalene epoxidase 155.5799 71.3 131.8107 Q9BS43 G19gh8 hypothetical protein MGC12435 592.1694 121 131.9022 P49788 D24ab8 retinoic acid receptor responder 97.19637 135 131.9355 Q9UP83 M10cd6 component of oligomeric golgi cc 100.2446 141 131.938 Q9Y2X0 N11cd5 thyroid hormone receptor-associ 116.8982 97.9 131.9541 Q9Y3E3 I15ef2 CGI-145 protein 94.76733 132 131.9919 O95183 J14cd6 vesicle-associated membrane pr 91.19765 157 132.0539 Q13242 N22cd3 splicing factor; arginine/serine-ri 156.0624 141 132.0637 Q9Y5R5 A06gh1 doublesex and mab-3 related tra 100.8446 162 132.1528 P04181 N02ab7 ornithine aminotransferase (gyra 112.3954 106 132.1687 Q14254 B15ab4 flotillin 2 130.1586 154 132.2038 Q9Y6E6 P08cd7 sirtuin silent mating type informa 94.40989 136 132.2501 Q9H237 D20gh5 porcupine 148.2204 258 132.2656 Q92785 N21cd2 requiern; apoptosis response zin 118.3718 108 132.3893 O95458 N11cd2 tubulin-specific chaperone d 128.9522 100 132.4761 P20749 P23ef6 B-cell CLL/lymphoma 3 264.1174 186 132.484 Q9H2N8 D24gh7 hypothetical protein GL012 104.3233 160 132.5137 Q15020 M08gh1 squamous cell carcinoma antige 117.2757 147 132.5393 P42025 O01gh1 ARP1 actin-related protein 1 hon 243.7979 92 132.554 P98173 I23gh5 2.19 gene 113.0426 116 132.6703 O95295 C06cd8 SNARE associated protein snapl 324.3312 119 132.6986 Q9NVA1 F15gh3 chromosome 20 open reading fr 111.7508 100 132.7232 P35573 O03ab2 amylo-1; 6-glucosidase; 4-alpha- 111.9583 106 132.7432 Q13126 K13ab7 methylthioadenosine phosphoryl 202.8169 236 132.9211 P43034 C11ab8 platelet-activating factor acetylhy 106.8174 125 132.987 Q01844 E15ab5 Ewing sarcoma breakpoint regio 111.2628 102 133.001 P27482 E18ab6 calmodulin-like 3 114.7017 104 133.018 Q9NUW4 N23gh3 BRIX 223.8591 77.1 133.0208 P78552 J23ab6 interleukin 13 receptor; alpha 1 118.2476 93.9 133.0765 P51843 O24ab2 nuclear receptor subfamily 0; gr 104.7329 112 133.1401 P15822 L23ab5 human immunodeficiency virus 83.26942 160 133.2118 Q9BXY9 O13gh8 RALBP1 associated Eps domain 90.84238 140 133.274 Q9ULB4 P10ef1 cadherin 9; type 2 (T1-cadherin) 275.2974 137 133.4641 Q9NZZ7 C08ef8 HSPC171 protein 214.9523 265 133.5412 Q02086 C09cd2 Sp2 transcription factor 101.0989 133 133.5465 Q9BUV9 H14gh6 DKFZP586J0119 protein 102.1174 119 133.5923 Q9UHJ9 A09ef4 FGF receptor activating protein 1 100.7903 121 133.6008 Q16401 E11cd1 proteasome (prosome; macropa 143.6091 120 133.6156 Q9Y4K4 D04cd6 mitogen-activated protein kinase 132.4072 158 133.6676 O60463 H06cd3 phosphalidic acid phosphatase 103.2417 151 133.6898 O95639 P20cd6 cleavage and polyadenylation sp 183.1762 67.6 133.7241 P50539 N19ab7 MAX interacting protein 1 175.6646 187 133.7304 Q9UH62 I15ef3 ALEX3 protein 118.2527 171 133.7314 O15525 C13ab7 v-maf musculoaponeurotic fibros 105.3252 109 133.7521 Q9H8T0 H21gh5 fused toes homolog (mouse) 106.2145 241 133.7606 Q9Y4X5 K03cd6 ariadne homolog; ubiquitin-conju 99.46477 128 133.8771 Q9H9E1 O01gh5 ankyrin repeat; family A (RFXAN 172.6266 78.8 134.052 Q93063 F13ab3 exostoses (multiple) 2 123.2886 161 134.3466 Q9H992 D22gh5 axotrophin 89.54768 149 134.4784 O43237 P02ab4 dynein; cytoplasmic; light interm 290.6769 119 134.4914 Q99643 H02cd1 succinate dehydrogenase compl 143.4474 125 134.5527 P24386 F11ef1 choroideremia (Rab escort protei 93.86058 129 134.5538 Q9Y5F7 F12gh4 protocadherin gamma subfamily 101.7878 114 134.5585 P06756 D14ab6 integrin: alpha V (vitronectin rec 200.0782 219 134.6115 Q9H5L7 C02gh6 chromosome 1 open reading frar 173.8106 148 134.6601 O15517 A14ef6 tumor necrosis factor receptor su 92.33364 207 134.6603 Q9P0N5 K24ef2 HSPC244 107.9991 129 134.6618 Q9NWT2 D19gh2 hypothetical protein FLJ20623 107.8864 105 134.7112 Q9Y2A0 O02cd7 TP53 target gene 1 127.408 88.2 134.8491 Q9NZ43 N16gh4 uncharacterized hematopoietic s 141.2548 137 134.9524 P27986 A10ef1 phosphoinositide-3-kinase; regul 111.3806 112 134.9586 Q9UBP6 J13ef1 methyltransferase-like 1 107.2187 122 134.986 Q9BWK5 P24gh5 hypothetical protein MGC5242 101.1324 123 134.9881 P54802 M24ab6 N-acetylglucosaminidase; alpha- 206.038 66.3 135.077 O75963 H09cd7 G-protein coupled receptor 110.3886 184 135.3412 Q9NXZ4 F03ef4 ELG protein 124.5205 105 135.3934 O60353 B11cd3 frizzled homolog 6 (Drosophila) 85.64918 146 135.5169 Q9NQS6 F13gh4 latexin protein 94.21822 163 135.5761 O14776 A19cd7 transcription elongation regulator 113.3803 117 135.6603 Q9Y5A2 L13ef1 putative zinc finger protein NY-R 154.0704 186 135.6708 P49842 G23cd6 serine/threonine kinase 19 133.3557 171 135.7013 Q06546 J14ab5 GA binding protein transcription 88.93312 138 135.7488 Q9Y2E7 I02ef8 KIAA0938 protein 109.8218 105 135.7763 Q9UM11 I02ef2 Fzr1 protein 80.82847 186 135.8949 Q99447 B14ab8 phosphate cytidylyltransferase 2; 174.8201 77.4 135.988 Q9H1R3 F22gh8 myosin light chain kinase 2; skel 93.58977 129 136.0456 P28358 P05ab6 homeo box D10 108.9905 102 136.1419 O76070 P18cd1 synuclein; gamma (breast cancer 128.551 140 136.1645 Q9Y5A7 N07ef2 NEDD8 ultimate buster-1 119.0653 195 136.2606 Q9NWY7 A16gh3 hypothetical protein FLJ20530 103.7638 110 136.3026 O43715 P02ef2 hypothetical protein HSPC132 137.4694 110 136.3043 Q9BY75 K19gh8 itchy homolog E3 ubiquitin protei 118.5721 127 136.5094 O43431 A12ef7 endothelial differentiation; lysop 126.4659 171 136.5393 O43567 D15cd7 ring finger protein 13 110.4449 153 136.5722 Q9Y2S7 P13ef8 DKFZP586F1524 protein 113.1366 104 136.7041 O14582 O24ef2 spondyloepiphyseal dysplasia; la 135.1666 135 136.7342 O75056 G12gh1 syndecan 3 (N-syndecan) 120.0661 162 136.797 Q9P2Y2 D18gh4 beta-1; 4 mannosyltransferase 89.6857 143 136.8208 Q16595 M08ab3 Friedreich alaxia 139.5657 130 136.8314 Q14807 B18ab7 kinesin-like 4 114.4726 94.2 136.9298 Q9BZL4 L10gh6 protein phosphatase 1; regulator 110.5367 123 137.0777 P30876 I13ab8 polymerase (RNA) II (DNA direct 265.5337 200 137.1153 Q9UGP6 B17cd7 coatomer protein complex; subu 94.73601 134 137.3091 P52655 M01ef2 general transcription factor IIA; 1 121.4896 128 137.3707 Q9HB07 G23gh5 chromosome 12 open reading fr 121.2547 118 137.4723 Q92940 H23ab7 MAD; mothers against decapent 414.4889 223 137.6028 Q9NWN1 H19gh2 hypothetical protein FLJ20727 117.7514 120 137.6351 O43664 A10cd6 G protein-coupled receptor 66 108.1311 102 137.6789 O14647 C19ab4 chromodomain helicase DNA bin 96.14904 164 137.7441 O75333 N15cd2 T-box 10 126.0065 129 137.7737 Q16539 J04ef5 mitogen-activated protein kinase 148.7339 219 137.8 Q9NQG5 A07gh5 chromosome 20 open reading fr 86.80552 143 137.803 Q15149 E05ab8 plectin 1; intermediate filament bi 125.7248 83.9 138.0785 Q9NVZ7 G12gh3 hypothitical protein FLJ10407 166.213 175 138.1444 Q15800 D02cd2 sterol-C4-methyl oxidase-like 171.8648 71.2 138.1497 Q9H0B6 D16gh5 hypothetical protein FLJ12387 si 96.54943 129 138.1542 P09001 K14cd7 mitochondrial ribosomal protein 94.17331 128 138.1601 O00301 D24cd3 KH-type splicing regulatory prote 126.0509 88.3 138.3014 P55786 J19ef7 aminopeptidase puromycin sensi 273.7328 98.9 138.3924 Q9Y5Y9 B14cd2 sodium channel; voltage-gated; t 127.3727 139 138.4331 P19235 M0ef7 erythropoietin receptor 198.5954 77.3 138.4803 O15228 A16ef3 glyceronephosphate O-acyltrans 225.1315 186 138.5137 Q9UK97 K05cd8 F-box only protein 9 151.0501 104 138.5593 P50990 D20cd6 chaperonin containing TCP1; sut 274.982 178 138.6001 Q9NZM1 P19cd8 fer-1-like 3; myoferlin (C. elegan 218.8411 202 138.6209 Q92924 N20cd1 SWI/SNF related; matrix associa 131.7669 82.7 138.6764 O75845 A18gh1 sterol-C5-desaturase (ERG3 dell 101.9285 153 138.7232 Q9NQ88 I10gh4 chromosome 12 open reading fr 80.2401 158 138.8274 Q16515 C19ab2 amiloride-sensitive cation chann 102.1159 109 138.9915 P49759 F16ab5 CDC-like kinase 1 86.24615 147 139.0985 P33552 A22ab5 CDC28 protein kinase 2 109.5671 96 139.1297 O75808 H21cd2 small optic lobes homolog (Dros 115.654 98.9 139.1625 Q9NXR1 M07gh2 LIS1-interacting protein NUDE1; 96.20481 123 139.1939 O75381 L12ab8 peroxisomal biogenesis factor 14 473.8395 113 139.2209 O60930 P23cd1 ribonuclease H1 167.3611 111 139.2393 O14653 P14cd4 golgi SNAP receptor complex me 115.7917 89.7 139.2541 Q16540 L24gh1 mitochondrial ribosomal protein 209.2433 120 139.3426 O14658 P06cd2 ras-related C3 botulinum toxin s 158.176 166 139.3634 Q15814 M17cd2 tubulin-specific chaperone c 103.3699 112 139.6311 Q9Y3C9 J09ef2 CGI-127 protein 83.4762 163 139.6599 P18827 F22cd1 syndecan 1 114.4045 92.7 139.6607 P04150 B21ab3 nuclear receptor subfamily 3; gro 106.6921 103 139.6889 Q9Y301 N05ef1 CGI-12 protein 108.0511 101 139.7035 O00626 F10cd1 small inducible cytokine subfamil 113.478 106 139.8189 B18cd8 neural precursor cell expressed; 108.1711 133 139.9597 Q9Y311 C01ef2 mitochondrial ribosomal protein 1 162.8519 74.8 139.9856 Q15633 K14cd2 TAR (HIV) RNA binding protein 169.3779 125 140.0138 P02278 M22gh6 H2B histone family; member K 100.2794 216 140.0965 P53672 J11cd7 crystallin; beta A2 101.7321 187 140.2804 P09417 C05ab8 quinoid dihydropteridine reducta 126.6361 161 140.3564 Q9HAY2 K14gh5 MAGEF1 protein 96.01675 126 140.3654 P30273 A20ab5 Fc fragment of IgE; high affinity I 88.48289 171 140.4541 Q92949 G10ab4 forkhead box J1 250.4112 167 140.5084 Q9GZT9 G01gh7 egl nine homolog 1 (C. elegans) 112.8025 99.2 140.6556 P35658 O23cd4 nucleoporin 214 kD (CAIN) 141.8279 137 140.7761 Q9HB40 G01gh5 likely homolog of rat mouse 105.9316 99.3 140.9548 O14686 O16cd3 myeloid/lymphoid or mixed-linea 117.844 157 141.0674 Q92911 O12cd1 solute carrier family 5 (sodium io 264.1256 125 141.0904 Q9Y5E4 B18ef3 protocadherin beta 5 95.08061 148 141.1894 Q13057 H17gh7 nucleotide binding protein 186.8796 125 141.2202 Q14863 B23ab8 POU domain; class 6; transcripti 103.2077 103 141.3258 P36610 G10ef3 frequenin homolog (Drosophila) 110.2191 136 141.4925 O60240 O12ab8 perilipin 1121.108 52.2 141.5046 Q9H9B4 P05gh5 hypothetical protein FLJ12876 87.99841 133 141.7125 O00584 J14cd3 ribonuclease 6 precursor 124.6932 250 141.8008 Q9H658 M04gh7 G protein-coupled receptor 107 158.2595 214 141.8139 P18858 K14ef6 ligase I; DNA; ATP-dependent 92.33071 128 141.8761 Q02877 D23cd1 ribosomal protein L26 449.1728 297 141.8851 P15586 J07ab4 glucosamine (N-acetyl)-6-sulfata 261.466 119 141.968 P42696 H08ef4 KIAA0117 protein 110.9202 231 141.9948 O75710 A17ef1 molybdenum cofactor synthesis 105.3087 101 142.0352 Q9NPI8 C01gh2 Fanconi anemia; complementatic 193.8104 214 142.0643 Q9HAR6 O10gh5 uterine-derived 14 kDa protein 118.9551 198 142.0669 P15018 O18ef7 leukemia inhibitory factor (cholin 253.8099 309 142.2733 Q13546 A23cd4 receptor (TNFRSF)-interacting s 139.7074 131 142.2746 P24298 H01ab4 glutamic-pyruvate transaminase 210.426 97.1 142.3123 Q14129 C22cd4 DiGeorge syndrome critical regio 112.1253 141 142.4302 Q9BQA2 K09gh8 KIAA1882 protein 164.9357 187 142.4325 Q9UJX9 B12ef3 hypothetical protein; estradiol-in 121.7396 98.5 142.5053 Q99590 I01cd5 splicing factor; arginine/serine-ri 231.0328 199 142.5273 O14798 C06ef7 tumor necrosis factor receptor su 142.6951 213 142.5294 P32238 P01ab3 cholecystokinin A receptor 487.368 168 142.5911 Q9UQ90 C17cd2 spastic paraplegia 7; paraplegin 101.2857 146 142.6321 P82980 M03gh8 retinol binding protein 5; cellular 111.2191 93.9 142.6923 P49716 P15ab5 CCAAT/enhancer binding protei 169.1889 73.4 142.8277 P20062 M12cd1 transcobalamin II; macrocytic an 125.6347 141 142.8402 P21580 B06cd2 tumor necrosis factor; alpha-indu 275.8225 317 142.8664 Q99774 H01cd5 protein phosphatase 4; regulator 195.85 173 143.1867 Q9P0T1 A17ef3 hypothetical protein HSPC192 104.4363 101 143.2517 P06737 B18ab8 phosphorylase; glycogen; liver ( 85.14818 139 143.2732 O15063 K10gh1 KIAA0355 gene product 149.9191 144 143.2945 P02743 K14ab2 amyloid P component; serum 108.0152 94.7 143.3031 Q9NVT0 I14gh3 hypothetical protein FLJ10534 136.4264 109 143.3056 Q9Y4P3 O07ef3 transducin (beta)-like 2 112.0852 104 143.4853 Q13886 N14ab3 basic transcription element bindi 164.4049 88.7 143.5269 Q9NVP8 L19gh4 hypothetical protein FLJ10595 101.7956 106 143.5829 P08240 G05cd2 signal recognition particle recept 158.3565 132 143.6823 P49459 M19ef5 ubiquitin-conjugating enzyme E2 98.6462 170 143.74 Q9NVAB L16gh2 solute carrier family 38; member 112.6488 127 143.7595 P25325 K23cd3 mercaptopyruvate sulfurtransfer 288.1435 274 143.8077 Q9UHI6 K08cd7 DEAD/H (Asp-Glu-Ala-Asp-His) t 135.6699 209 143.8383 P52298 H01cd7 nuclear cap binding protein subu 138.9223 191 143.8819 Q9NQ30 A10cd7 endothelial cell-specific molecut 104.1846 122 143.9703 O00541 I08ef3 pescadillo homolog 1; containing 180.43 204 144.0988 Q9H2V9 B06gh7 hypothetical protein CDA08 173.5608 169 144.1057 Q9NNX1 F12gh1 tuftelin 1 147.0323 175 144.106 Q13508 H14ab2 ADP-ribosyltransferase 3 109.4052 101 144.1545 Q9NR30 B21gh6 DEADE/H (Asp-Glu-Ala-Asp/His) t 110.4836 130 144.2348 Q14320 E15cd5 DNA segment on choromosome X 102.5057 178 144.2677 Q04726 D03cd2 transducin-like enhancer of split 211.8773 115 144.3217 P20061 N13cd1 transcobalamin I (vitamin B12 bi 177.3445 85.5 144.4835 Q9Y2Y1 J12ef2 polymerase (RNA) III (DNA direc 153.7426 145 144.5561 P35754 G22ab5 glutaredoxin (thioltransferase) 153.823 138 144.7308 Q02978 F01cd3 solute carrier family 25 (mitocho 106.877 98.2 144.7822 O95792 N20gh2 protein associated with PRK1 130.6914 146 144.7909 Q13232 D20ef7 non-metastatic cells 3; protein e 90.7906 156 144.8861 Q9NVH2 L01ef8 DKFZP434B168 protein 117.6587 91.2 144.9821 Q15561 O15cd2 TEA domain family member 4 234.306 172 145.3307 Q9UPN9 B01ef2 tripartite motif-containing 33 110.9269 135 145.3321 Q14353 O06ab3 guanidinoacetate N-methyltrans 109.1385 103 145.3798 Q9NZM5 A18ef4 glioma tumor suppressor candid 150.098 122 145.587 O43255 B11cd2 seven in absentia homolog 2 (D 114.6318 101 145.653 Q14331 G04ab5 FSHD region gene 1 164.0964 176 145.6576 P18847 N23ab5 activating transcription factor 3 127.5442 154 145.6654 O60258 I07cd4 fibroblast growth factor 17 159.7671 223 145.6821 P47929 P02ab6 lectin; galactoside-binding; solub 151.1595 92.8 145.699 P35227 O14cd4 zinc finger protein 144 (Mel-18) 108.2295 151 145.8554 Q15599 O15cd5 solute carrier family 9 (sodium/h 168.9673 80.5 145.993 Q9UKJ5 B20cd7 cystein-rich hydrophobic domain 184.4717 206 145.9967 Q9HCB9 C10gh5 chromosome 1 open reading frar 94.16759 126 146.1683 Q9Y3A0 K07ef2 CGI-92 protein 119.1033 178 146.1698 P49815 M17ef6 tuberous sclerosis 2 106.0159 163 146.2712 P25116 L19ab4 coagulation factor II (thrombin) r 82.48228 143 146.2742 O75829 O01cd7 chondromodulin I precursor 121.7658 119 146.4876 Q9NYI1 M16ef2 ECSIT 111.7926 110 146.6345 P24347 I24ef5 matrix metalloproteinase 11 (stro 97.57916 136 146.649 O43189 K24ab8 PHD finger protein 1 112.1101 101 146.6925 Q9P029 N22ef2 TH1-like (Drosophila) 201.2292 159 146.6998 Q9NZP9 E17ef2 immediate early response 5 105.1683 157 146.761 Q9UIA3 I12ef2 neutral sphingomyelinase 165.6408 147 146.8134 Q99734 M12ef5 Notch homolog 2 (Drosophila) 220.4251 263 147.0111 O00411 C19cd1 polymerase (RNA) mitochondrial 120.5078 105 147.0481 P28347 P04gh1 TEA domain family member 1 (S 230.2101 174 147.0913 Q13619 G19gh1 cullin 4A 153.1592 218 147.2043 O94929 O06ef8 KIAA0843 protein 108.7821 99.4 147.2921 Q9P026 A02ef8 HSPC134 protein 115.4895 184 147.3205 P28067 D08ab5 major histocompatibility complex; 128.7098 100 147.3934 Q14126 E11ef7 desmoglein 2 426.8387 366 147.4196 Q14267 P01cd1 regulatory factor X: 4 (influences 127.7912 98.9 147.4351 P55197 H09ab2 myeloid/lymphoid or mixed-linea 160.668 185 147.4439 Q9NP87 O20cd8 polymerase (DNA directed); mu 115.1765 86.7 147.4845 P04155 A04cd2 trefoil factor 1 (breast cancer; es 258.058 136 147.487 Q9C069 N02gh7 sec13-like protein 52.65015 424 147.5255 P12270 G14cd2 translocated promoter region (to 104.4493 136 147.7447 Q9UIG6 I14ef2 LPAP for lysophosphatidic acid 218.3106 325 147.8779 O15453 P08cd5 NBR2 99.08545 108 147.9143 Q9UNW8 F17cd8 G protein-coupled receptor 239.3255 347 148.021 P06746 I10ef6 polymerase (DNA directed); beta 142.5013 225 148.0351 O15414 I08cd7 trinucleotide repeat containing 4 131.6219 199 148.0947 O15259 L22ab7 nephronophthisis 1 (juvenile) 115.0436 110 148.3613 Q9NRA8 P05gh4 eIF4E-transporter 106.343 178 148.4323 Q9NP77 C10ef8 HSPC182 protein 171.17 175 148.5234 Q06587 P17cd1 ring finger protein 1 119.2377 127 148.657 Q9Y5Z5 E22ef2 heme binding protein 1 181.0768 196 148.7681 O15327 I05cd4 inositol polyphosphate-4-phosph 183.6815 131 148.785 P49646 P19cd1 regulator of mitotic spindle assen 143.9463 117 148.8487 Q99809 F16cd5 conserved gene amplified in oste 134.0126 91.3 148.9901 Q9UBM1 G02cd7 phosphatidylethanolamine N-mel 138.4849 122 149.0109 P16403 G04ab6 H1 histone family; member 2 427.1258 558 149.1016 O75503 B01ab4 ceroid-lipofuscinosis; neuronal 5 148.9991 75.4 149.1361 P15814 P20gh6 immunoglobulin lambda-like poly 78.91644 144 149.2005 Q03164 N01ab7 myeloid/lymphoid or mixed-linea 157.0713 81.9 149.358 Q13624 B08ef6 interleukin enhancer binding fact 136.4076 130 149.4265 Q14118 M02ab5 dystroglycan 1 (dystrophin-assoc 105.7987 99 149.6192 Q13286 E20ab3 ceroid-lipofuscinosis; neuronal 3; 240.521 302 149.6542 Q9Y5Q0 E15gh7 fatty acid desaturase 3 117.0825 115 149.704 Q9P0R1 K08ef2 forkhead box P1 99.17408 114 149.7517 P41182 C24ab5 B-cell CLL/lymphoma 6 (zinc fing 115.9704 85.9 149.853 O75497 K14cd6 microspherule protein 1 145.7927 163 149.9313 Q14185 M19ab4 dedicator of cyto-kinesis 1 95.3322 112 150.0398 O95163 P05cd3 inhibitor of kappa light polypeptic 203.0161 120 150.0489 Q14508 L05ef7 WAP four-disulfide core domain: 102.6084 201 150.0782 P25942 M21ef7 tumor necrosis factor receptor su 110.0933 239 150.083 Q9Y6E0 F15cd3 serine/threonine kinase 24 (STE: 206.7079 225 150.279 Q9UQF2 J21cd5 mitogen-activated protein kinase 229.9384 182 150.2902 Q9Y285 D11ab5 phenylalanine-tRNA synthetase- 179.7613 145 150.3716 Q04762 F09ab4 cell matrix adhesion regulator 134.1594 176 150.3997 Q9Y6J9 P19ef6 TAF6-like RNA polymerase II; p3 77.59128 158 150.4181 O43913 C06ab8 origin recognition complex; subu 147.9187 168 150.4866 P25208 M05cd1 nuclear transcription factor Y; be 106.4862 138 150.5231 Q9H9X4 F03gh5 hypothetical protein FLJ11618 189.58 179 150.5879 O95297 P17cd4 myelin protein zero-like 1 127.461 121 150.7509 Q9UPG8 O06ab8 pleiomorphic adenoma gene-like 134.8747 165 150.9533 P16333 H16ef5 NCK adaptor protein 1 237.1463 351 150.9549 Q14108 I22ab5 CD36 antigen (collagen type I re 155.206 139 150.9785 Q9UFF9 O05cd5 CCR4-NOT transcription comple 162.9025 208 151.0687 O15242 O19ab8 nardilysin (N-arginine dibasic co 210.0164 198 151.1245 Q13442 N15ef3 PDGFA associated protein 1 156.1376 188 151.1314 Q99755 A15ef6 phosphatidylinositol-4-phosphat 112.2177 146 151.3432 Q9NZV1 E09gh2 cysteine-rich motor neuron 1 112.5932 99.1 151.3541 Q05195 C09ab7 MAX dimerization protein 136.8996 254 151.5662 O95671 J14ab2 acetylserotonin O-methyltransfer 99.67178 98.5 151.7064 Q9Y658 A09ef2 RNA helicase 112.9715 95.3 151.8988 Q9BTU6 N12gh6 phosphatidylinositol 4-kinase typ 97.30862 178 151.965 Q9UPN6 G04ef8 KIAA1116 protein 127.681 113 152.0268 O00170 J03ab2 aryl hydrocarbon receptor intera 555.1127 223 152.0508 Q9UJW6 P01ef3 activity-regulated cytoskeleton-a 221.8559 185 152.1474 Q9HCT0 N02ef8 fibroblast growth factor 22 157.7471 126 152.2042 Q15459 O03cd6 splicing factor 3a; subunit 1; 120 163.4432 145 152.3945 O95400 G16cd6 CD2 antigen (cytoplasmic tail) bi 192.2313 238 152.5257 P07954 M06ab3 fumarate hydratase 121.2546 142 152.5652 Q9H6Z5 C16gh5 hypothetical protein FLJ21634 101.1467 152 152.6745 Q9HCN8 A05gh1 stromal cell-derived factor 2-like 136.5604 128 152.9097 Q92890 A24cd4 ubiquitin fusion degradation 1-lik 157.2559 220 152.9538 O43324 N24cd4 eukaryotic translation elongation 150.6748 112 152.9613 Q9NVU8 H10gh2 hypothetical protein FLJ10496 145.4398 119 152.9651 Q9NQW6 H01ef4 anillin; actin binding protein (scr 113.8655 85.6 152.992 Q9NWH4 L01gh2 mitochondrial ribosomal protein 173.4347 107 153.0783 Q9UBV8 M13cd8 PEF protein with a long N-termin 146.0371 144 153.0828 P15328 F10ab3 folate receptor 1 (adult) 152.5051 123 153.1163 Q9Y583 B01cd6 NS1-associated protein 1 143.6283 177 153.2797 Q07326 M08ab8 phosphatidylinositol glycan; clas 132.6521 93 153.3084 O75396 M12cd5 SEC22 vesicle trafficking protein 143.9018 153 153.3626 Q9Y2Z8 D09ef2 CGI-09 protein 117.2943 110 153.5282 Q9H3P7 N05gh5 golgi phosphoprotein 1 251.3681 258 153.65 O95678 E03cd5 cytokeratin type II 339.3692 195 153.797 P17026 M04cd4 zinc finger protein 22 (KOX 15) 152.726 88.3 153.8779 Q9Y3N9 M05gh7 olfactory receptor; family 2; subf 127.2527 137 153.9228 Q9BYT8 K08gh7 neurolysin (metallopeptidase M3 85.99781 193 154.0005 Q9UHQ7 F02ef8 pp21 homolog 119.2248 136 154.0057 O60921 A22ab7 HUS1 checkpoint homolog (S. p 148.5718 204 154.126 O00400 D05ab2 acetyl-Coenzyme A transporter 196.9505 124 154.2012 Q9Y690 H01gh6 mortality factor 4 253.2426 259 154.2307 Q9NZL9 L24ef7 methionine adenosyltransferase 128.4144 99.7 154.2681 O60563 A05ab4 cyclin T1 179.5706 171 154.2911 P20591 M03ab7 myxovirus (influenza virus) resist 459.0611 873 154.338 Q9BQC6 P14gh5 mitochondrial ribosomal protein 188.6422 74.3 154.357 P28838 J02ef1 leucine aminopeptidase 3 409.1007 383 154.3828 Q9NZE5 P08ef1 hypothetical protein LOC51319 135.1502 171 154.3904 Q9NX47 K10gh2 hypothetical protein FLJ20445 299.3918 338 154.4327 O60612 K11cd2 supervillin 113.628 270 154.4497 O00559 F22cd4 estrogen receptor binding site as 181.5726 147 154.679 Q9NUU9 E17gh3 hypothetical protein F23149_1 140.3785 224 154.7106 P22059 C10ab8 oxysterol binding protein 133.2924 93.6 154.8714 O00408 I05ef6 phosphodiesterase 2A; cGMP-sti 860.2983 169 154.9688 O94935 P22ef7 SAC1 suppressor of actin mutati 146.0417 128 154.9914 P41134 H15ef5 inhibitor of DNA binding 1; domi 434.1844 292 155.0439 P24407 M08ab7 mel transforming oncogene (deri 224.1153 189 155.1684 O00232 N05ab8 proteasome (prosome; macropa 122.517 139 155.2465 Q01432 G04ab2 adenosine monophosphate dea 111.1768 117 155.341 Q13525 G15cd4 interleukin 1 receptor-like 2 136.0802 130 155.4674 Q16611 N04ab3 BCL2-antagonist/killer 1 280.4131 194 155.5414 Q9NPA3 C11gh5 hypothetical protein STRAIT114 112.5378 85.5 155.5531 Q9GZM8 D14gh7 LIS1-interacting protein NUDEL; 137.8235 131 155.5611 P42702 P06ab6 leukemia inhibitory factor recept 92.44914 112 155.6189 Q05940 P07ef5 solute carrier family 18 (vesicular 374.4901 153 155.637 Q9Y3Q5 H18cd6 putative DNA/chromatin binding 75.96908 150 155.6726 Q15756 H08ab7 potassium inwardly-rectifying ch 149.0689 80.9 155.7504 O75386 M17cd3 tubby like protein 3 128.6914 82.7 155.7811 P50750 D03ef5 cyclin-dependent kinase 9 (CDC: 270.8229 215 155.8317 Q9NWY6 A18gh3 hypothetical protein FLJ20531 91.85185 130 156.1332 P50391 K05cd1 pancreatic polypeptide receptor 136.5278 112 156.1953 Q9NX07 L20gh6 tRNA selenocysteine associated 258.434 287 156.2449 O75354 A15ab4 ectonucleoside triphosphate dip 386.4989 258 156.4638 Q9H832 L12gh5 hypothetical protein FLJ13855 173.4437 307 156.9292 Q9UBW8 F18ef1 COP9 constitutive photomorpho 102.8052 111 157.0119 P14136 E23ab5 glial fibrillary acidic protein 108.166 86.6 157.2761 Q9NYF3 F08ef1 chromosome 5 open reading frar 121.4116 94.3 157.5806 Q15056 A09gh2 Williams-Beuren syndrome chror 202.4969 124 157.6763 O15534 I16ab8 period homolog 1 (Drosophila) 237.2007 143 157.7195 Q9Y399 O21ef2 mitochondrial ribosomal protein 229.9134 139 157.7339 O14972 A04cd6 Down syndrome critical region g 230.0837 267 157.7386 Q14113 M15ab2 AE binding protein 1 124.9796 95.3 157.955 O95755 O18cd5 RAB36; member RAS oncogene 132.9919 97 158.0474 Q9NPC3 I09gh4 enhancer of invasion 10 104.2128 121 158.1023 Q9Y6E9 N24cd7 sirtuin silent mating type informal 111.8557 153 158.2227 Q9Y5B8 D17cd8 NME7 92.69165 116 158.2444 P49642 I21ab8 primase; polypeptide 1 (49 kD) 135.2376 70.2 158.2887 O60660 J04ab2 ash2 (absent; small; or homeotic 274.3502 177 158.3372 Q9H251 O08gh7 cadherin related 23 113.1038 184 158.4524 Q9Y6C2 A22cd7 elastin microfibril interface locate 107.9751 92.2 158.6648 O95825 D13cd5 crystallin; zeta (quinone reducta 144.0183 133 158.6719 Q9UHG3 J02ef2 prenylcysteine lyase 250.3969 207 158.8419 O00629 J18ab6 karyopherin alpha 4 (importin alp 518.8184 295 158.8458 Q15397 B14gh1 KIAA0020 gene product 109.8533 134 158.9595 Q14999 H01gh1 KIAA0076 gene product 71.35119 173 159.0037 Q12772 M18cd2 sterol regulatory element binding 158.6108 94.6 159.1986 O75150 F09gh1 ring finger protein 40 129.2351 169 159.2038 O43423 L07gh6 acidic (leucine-rich) nuclear pho 140.3006 143 159.4372 O43311 D12cd8 muscleblind-like (Drosophila) 165.2243 99.4 159.4681 Q9NYX4 B07ef4 calcyon; D1 dopamine receptor- 207.2791 147 159.5302 Q9HD71 G04gh4 hypothetical nuclear factor SBB 123.7874 140 159.5491 Q9NZH2 N03cd8 replication initiation region prote 225.0949 179 159.6113 Q9NVH1 B05gh3 hypothetical protein FLJ10737 137.4673 217 159.6304 Q9NVG3 B11gh3 hypothetical protein FLJ10751 96.28296 105 159.6829 P52179 A21cd4 myomesin 1 (skelemin) (185 kD) 157.0608 94 159.8272 O94815 B09cd3 frizzled homolog 1 (Drosophila) 93.97877 101 159.9198 Q9UBY9 G01ef4 heat shock 27 kD protein family; 98.97552 102 160.1725 Q9NVX7 G18gh3 hypothetical protein FLJ10450 111.5196 121 160.2507 O95704 A02cd6 FE65-like protein 2 99.35088 115 160.3239 P19801 A23ab2 amiloride binding protein 1 (amin 164.6296 68.3 160.3477 O43709 L18ef3 Williams Beuren syndrome chror 127.8538 134 160.4415 Q12839 N24ef1 H326 109.677 116 160.6141 O43503 D10ab8 RAD51 homolog C (S. cerevisiae 96.34779 97.6 160.6551 Q07898 J10cd4 CD163 antigen 87.73563 177 160.8614 O96015 F22cd5 dynein; axonemal; light polypepti 94.54055 251 160.9963 Q92524 L11ab8 proteasome (prosome; macropal 396.6515 220 161.0391 Q92692 B06ab8 poliovirus receptor-related 2 (her 302.7185 317 161.2569 Q9Y6Y8 I16cd7 Sec23-interacting protein p125 104.2429 131 161.2684 Q9NZ78 J16gh3 uncharacterized bone marrow pn 107.2001 127 161.3587 Q15120 G15cd1 pyruvate dehydrogenase kinase; 96.64061 107 161.6468 P35241 F22ab8 radixin 276.6012 213 161.7003 Q9Y326 D23ef2 brain specific protein 359.3582 160 161.7123 Q92600 J03cd5 RCD1 required for cell differentia 115.6633 145 161.7142 O00487 N14cd5 26S proteasome-associated pad 329.3518 275 161.8834 Q9Y689 P21cd7 ADP-ribosylation factor-like 5 137.7737 159 161.8965 Q9ULB8 P05cd8 CMP-NeuAC: (beta)-N-acetylgala 91.01128 121 161.9148 O60897 L09cd7 RAB; member of RAS oncogene 89.32474 112 162.0127 P51809 J05cd2 synaptobrevin-like 1 228.3546 141 162.1052 O75581 A03ab7 low density lipoprotein receptor-r 122.4708 125 162.1159 O43795 F12ef4 myosin class I; myh-1c 259.4543 282 162.137 Q14188 H17ef5 transcription factor Dp-2 (E2F dir 107.308 204 162.1489 P06280 B07ab3 galactosidase; alpha 178.0238 304 162.2871 Q14541 O17ab7 hepatocyte nuclear factor 4; gam 549.8997 283 162.4659 P57723 E17gh8 poly(rC) binding protein 4 186.2845 231 162.5267 Q9NWU3 A24gh3 DEAD/H (Asp-Glu-Ala-Asp/His) t 154.71 104 162.6529 Q9NPC5 J16ef8 nudix (nucleoside diphosphate 107.1863 98.4 162.6929 Q9Y3C5 B19ef3 ring finger protein 11 160.0631 164 162.7518 Q9NWX3 B01gh2 chromosome 20 open reading fr 98.58482 95.6 162.7744 P52742 I22cd3 zinc finger portein 135 (clone pH 81.4141 121 162.8382 Q9Y313 D17ef2 PTD013 protein 90.25232 116 163.4053 Q9P2W9 B11ef4 syntaxin 18 128.6426 188 163.4277 P14778 F09ab6 interleukin 1 receptor; type I 264.5401 539 163.4432 Q15464 I12ef5 SHB (Src homology 2 domain co 284.291 301 163.5379 O15444 H07cd2 small inducible cytokine subfamil 244.6426 97.1 163.6053 P49796 P14ef4 regulator of G-protein signalling: 220.2769 99.3 163.6222 Q9NUS7 B04gh3 hypothetical protein FLJ11164 81.76063 114 163.6422 P48651 L11ef3 phosphatidylserine synthase 1 211.8695 139 163.6792 Q07706 F15cd4 tetracycline transporter-like prote 143.0791 144 163.7206 O75143 B11gh1 KIAA0652 gene product 106.5331 155 163.7687 O75039 L19gh1 KIAA0451 gene product 174.142 135 163.8572 P02261 M10gh6 H2A histone family; member N 93.48591 273 163.8621 Q9H9A0 L20gh5 hypothetical protein FLJ12895 86.42599 130 164.3655 Q9NV35 J21gh3 hypothetical protein FLJ10958 99.15342 154 164.4852 Q9P1G8 C05gh4 WW domain-containing adapter 119.4436 182 164.5311 P26368 D11cd7 U2 small nuclear ribonucleoprote 217.0564 107 164.8861 Q9BSZ7 E11gh8 DEAD/H (Asp-Glu-Ala-Asp/His) t 130.7858 111 164.9084 Q9Y391 G23ef2 androgen-regulated short-chain 222.3497 128 164.9823 Q9NYR5 E05ef3 HSPC126 protein 99.37243 110 165.2098 P05165 N12ab7 propionyl Coenzyme A carboxyla 100.892 120 165.6902 Q9NPF4 O21gh3 O-sialoglycoprotein endopeptida 103.8223 112 165.9716 P16106 D01cd3 H3 histone family; member K 99.19006 130 166.1216 P35249 O03ef5 replication factor C (activator 1) 105.2406 98.7 166.2092 P28702 P18gh1 retinoid X receptor; beta 74.914 142 166.2214 P49674 K14ab4 casein kinase 1; epsilon 99.33956 145 166.3564 Q9NXW2 I03gh2 DnaJ (Hsp40) homolog; subfamil 247.7907 235 166.4412 O14672 I01ab2 a disintegrin and metalloproteina 378.0042 226 166.5417 Q9Y5B9 I20cd7 chromatin-specific transcription 163.0543 188 166.6045 Q9H9J2 H22gh5 mitochondrial ribosomal protein 206.428 256 166.8142 P23759 G06ab8 paired box gene 7 92.41833 200 166.8514 Q16643 L05ab4 drebrin 1 265.008 152 166.9734 P48454 I21cd1 protein phosphatase 3 (formerly: 105.9496 169 167.0428 Q9Y508 F21ef4 zinc finger protein 313 331.595 395 167.2366 P19474 G09cd2 Sjogren syndrome antigen A1 (5: 301.1776 183 167.414 P46109 N13ab5 v-crk sarcoma virus CT10 oncog 151.2065 141 167.7716 P54855 B19cd4 UDP glycosyltransferase 2 family 137.8939 127 167.8346 Q14242 H14cd1 selectin P ligand 112.9679 130 167.9184 Q9BSS1 P17gh8 hypothetical protein FLJ14525 86.75908 113 167.974 Q9Y3B2 L23ef1 homolog of yeast exosomal core 152.0751 140 167.9915 P31391 N03cd1 somatostatin receptor 4 147.3942 92.5 168.0254 O60623 O03ab4 diptheria toxin resistance protein 210.9658 170 168.0762 Q99959 L24ab8 plakophilin 2 362.9423 211 168.1655 B21gh7 leukocyte immunoglobulin-like re 139.2571 234 168.1829 Q01658 P18ab5 down-regulator of transcription 1: 205.2249 122 168.2606 Q9HCS4 P10gh7 HMG-box transcription factor TCI 76.48423 156 168.2926 Q9P035 N20ef2 butyrate-induced transcript 1 102.716 142 168.3034 Q9C0K7 P24gh3 amyotrophic lateral sclerosis 2 ( 102.352 108 168.4355 Q9NYF4 I13ef3 chromosome 5 open reading frar 89.72908 137 168.4424 P30042 M19cd4 chromosome 21 open reading fra 98.84241 97.5 168.5171 O75325 K16cd6 glioma amplified on chromosome 116.3239 83.3 168.5172 Q9Y670 N01ef2 transient receptor potential catio 96.41826 90.8 168.5297 Q9UPR8 I14ef8 KIAA1084 protein 101.3235 111 168.5336 Q9Y2X7 I21ef4 G protein-coupled receptor kinas 160.7403 167 168.7352 P47872 D24cd1 secretin receptor 174.6672 209 168.738 O43353 C17cd4 receptor-interacting serine-threo 272.5279 388 168.7722 P32321 P14ab5 dCMP deaminase 218.5685 60.1 168.8404 O43612 J16ab4 hypocretin (orexin) neuropeptide 66.45691 194 168.9064 Q92874 M15ab4 deoxyribonuclease I-like 2 218.1787 146 168.9596 Q9UI90 I15ef8 PRO0038 protein 89.17218 389 168.9849 P30519 N05ab6 heme oxygenase (decycling) 2 586.3897 387 169.1269 Q9NVE7 D03gh3 hypothetical protein FLJ10782 141.6695 148 169.2644 Q9P010 A14ef8 HSPC154 protein 227.9143 246 169.4393 Q9UH59 M04cd8 bromodomain-containing 7 147.6635 103 169.5045 Q9UM82 E01cd6 spermatogenesis associated 2 230.7114 221 169.6678 Q9P2Y4 N14ef1 zinc finger protein 219 105.6753 175 169.7666 Q9GZS3 H19gh7 recombination protein REC14 124.7245 162 169.9984 P07686 J17ab3 hexosaminidase B (beta polypep 217.0423 135 170.0092 Q9NZV6 L06ef2 selenoprotein X; 1 241.3633 202 170.0232 O14678 E17cd1 ATP-binding cassette; sub-family 77.65216 127 170.0525 P29972 O04ab2 aquaporin 1 (channel-forming int 309.1218 134 170.2078 O95373 D03cd6 RAN binding protein 7 247.4368 113 170.45 Q15436 O12cd6 Sec23 homolog A (S. cerevisiae) 90.05071 100 170.9386 Q9BQ67 K23gh6 glutamate rich WD repeat protein 140.3198 112 170.966 P35321 D21gh6 small proline-rich protein 1A 62.28271 237 171.0104 Q9UPQ8 I10ef8 KIAA1094 protein 76.76245 123 171.0467 O43292 A19cd4 GPAA1P anchor attachment prot 95.36294 92.4 171.0704 Q9UBM3 G02cd1 proteasome (prosome; macropai 287.6026 204 171.1554 P19338 M20ab7 nucleolin 148.8642 87.6 171.2094 Q9NPE6 E17gh1 sperm associated antigen 4 111.172 135 171.4356 O00442 J12cd3 RTC domain containing 1 274.6701 279 171.531 P28356 D09ef1 homeo box D9 84.5638 106 171.5949 P49447 G06ef1 cytochrome b-561 174.7152 167 171.6447 Q9UQA4 P18cd4 nuclear factor (erythroid-derived 227.4253 470 171.8945 O15254 D09ab2 acyl-Coenzyme A oxidase 3; pris 192.2301 192 172.0218 Q9NWW6 B11gh2 hypothetical protein FLJ20559 198.7861 220 172.0261 O75391 M08cd5 sperm associated antigen 7 154.1159 140 172.0658 Q92959 H19cd2 solute carrier family 21 (prostag 86.25485 102 172.112 O00499 G06ab2 bridging integrator 1 162.8584 111 172.4453 Q14197 J05ab6 immature colon carcinoma trans 90.92583 102 172.5526 Q9NXS9 K15gh2 hypothetical protein FLJ20071 121.4575 103 172.5552 O75954 N18cd6 tetraspan transmembrane 4 sup 83.06795 119 172.5557 Q9UJY9 E17cd8 lifeguard 156.5909 75.6 172.6495 P82912 F10gh5 mitochondrial ribosomal protein 105.0578 196 172.7091 Q12918 J02ab6 killer cell lectin-like receptor sub 205.6225 290 172.8141 Q14789 E01ab6 golgi autoantigen; golgin subfam 96.09162 194 173.0059 Q04206 I23ef6 v-rel reticuloendotheliosis viral o 328.9295 242 173.0443 P19838 M15ef5 nuclear factor of kappa light poly 229.2262 277 173.0997 Q92748 A24cd2 thyroid hormone responsive (SP 101.3906 88.2 173.314 O95095 P13ab2 amyloid beta precursor protein ( 199.951 201 173.3314 P52209 K18ab8 phosphogluconate dehydrogena 211.8178 147 173.42 P42566 H10ef5 epidermal growth factor receptor 194.9437 158 173.4643 Q13772 D05gh6 nuclear receptor coactivator 4 273.5167 367 173.5038 P43897 D09gh6 Ts translation elongation factor; 325.7575 226 173.8489 P09329 D08ef7 phosphoribosyl pyrophosphate 103.7882 86.2 174.5738 O75618 F24cd4 death effector domain-containing 172.0163 176 174.7689 Q9UHI9 B18ef1 flavohemoprotein b5 + b5R 169.2028 197 174.7919 Q9H824 J07gh6 F-box only protein 22 89.2751 161 175.62 Q9UQ43 G07ab3 BAI1-associated protein 2 184.8198 165 175.6399 O43173 N08ef1 sialyltransferase 8C (alpha2; 3Ga 220.9909 256 175.9869 Q9BZZ2 G13gh7 sialoadhesin 147.52 189 175.9952 Q92611 I16gh1 KIAA0212 gene product 96.3144 94.3 176.0348 Q969V6 K14gh7 megakaryoblastic leukemia (tran 135.6533 161 176.0531 P08107 K14ab7 heat shock 70 kD protein 1B 153.5141 106 176.1145 Q9BQ24 E21gh6 hypothetical protein MGC2550 153.9741 255 176.3889 Q9H7X1 N07gh5 hypothetical protein FLJ14153 155.291 236 176.5938 Q99616 D09cd2 small inducible cytokine subfamil 130.1641 100 176.5958 Q92896 L04cd7 golgi apparatus protein 1 97.73429 90.3 176.622 Q14582 J16ef6 Mad4 homolog 210.3185 244 176.6383 Q13505 K21ab7 metaxin 1 199.1231 168 176.6745 Q13722 O24cd8 chromosome 3p21.1 gene seque 85.85963 144 176.7101 P01308 I10ab6 insulin 367.022 113 176.7437 O00405 D19ab8 protein phosphatase 1; regulator 233.0866 306 176.8763 P41215 E03ab5 fatty-acid-Coenzyme A ligase; lo 267.9822 199 177.1301 P31314 F04ef6 homeo box 11 (T-cell lymphoma 107.4127 170 177.4236 O95427 G21cd8 phosphatidylinositol glycan; clas 84.22817 116 177.4629 Q12981 C24ef6 BCL2/adenovirus E1B 19 kD inte 82.38214 99.8 177.5246 Q9Y5V1 L10ef1 HSPC042 protein 212.074 184 177.7635 Q9H4B4 O22ab4 cytokine-inducible kinase 161.982 194 177.788 Q9H6D1 P15gh5 chromosome 20 open reading fr 95.43432 108 177.8526 O60504 J18cd5 vinexin beta (SH3-containing ad 109.3831 99.8 177.8876 Q9UNK0 I02cd5 syntaxin 8 218.2149 171 177.9777 O95657 B24cd4 proline-serine-threonine phosph 369.9485 158 178.0072 P20645 C05ab7 mannose-6-phosphate receptor ( 355.8249 234 178.1318 O14569 B03ab2 putative tumor suppressor 122.4884 79.2 178.136 O15293 D18cd3 MAP-kinase activating death don 157.092 114 178.1677 P00390 E14ef7 glutathione reductase 282.1492 196 178.1741 Q9HBV3 K24gh5 PP3111 protein 229.2714 361 178.4093 Q14558 H17ab8 phosphoribosyl pyrophosphate 301.219 227 178.4567 O14710 F01ef5 cell cycle progression 2 protein 261.2178 189 178.7923 Q9UJ70 J10ef3 N-acetylglucosamine kinase 151.2986 276 178.7992 Q13397 M18cd6 zinc finger protein 238 215.883 285 178.9318 Q9NRG4 B21gh4 HSKM-B protein 143.1326 279 178.999 P51449 B01cd2 RAR-related orphan receptor C 236.6977 97.2 179.0372 Q9H768 O21gh7 synaptotagmin-like 2 83.78255 121 179.0813 Q14332 F22ef5 frizzled homolog 2 (Drosophila) 86.25011 129 179.1323 Q13207 N13cd2 T-box 2 118.9378 108 179.1858 Q9H6B8 B19gh5 hypothetical protein similar to m 134.338 129 179.5015 O00462 J09ab7 mannosidase; beta A; lysosomal 83.23817 107 179.6953 Q9Y3D8 H14ef2 adrenal gland protein AD-004 178.4931 163 179.7989 P17900 F19ab3 GM2 ganglioside activator protei 124.7747 232 179.914 Q9P0M4 O10cd8 interleukin 17C 260.8753 223 180.0241 F13gh8 G protein-coupled receptor 54 87.92591 133 180.0735 Q9NZ92 J02gh3 SWI/SNF related; matrix associa 267.7307 247 180.206 Q9NX94 L18gh6 hypothetical protein FLJ20154 133.6318 165 180.3424 P04049 G12ef5 v-raf-1 murine leukemia viral onc 225.086 183 180.3925 Q13181 B06cd1 ATP-binding cassette; sub-family 167.9383 127 180.4651 P22102 M05ab6 phosphoribosylglycinamide form 295.0489 180 180.5026 Q9NQZ8 A09gh5 endothelial zinc finger protein inc 96.79284 138 180.7283 Q9UN30 D04cd2 sex comb on midleg-like 1 (Dros 97.47885 86 181.0121 P26651 J04ef6 zinc finger protein 36; C3H type; 286.0733 162 181.0638 P18887 O06ef6 X-ray repair complementing defe 85.61601 102 181.0778 Q9Y2S0 P14ef1 RNA polymerase I 16 kDa subun 182.9338 149 181.2184 P49023 I05ef7 paxillin 313.7788 334 181.2995 P49321 O03ab7 nuclear autoantigenic sperm pro 119.903 78.2 181.3524 Q13428 M14cd1 Treacher Collins-Franceschetti s 164.3621 123 181.4282 Q9HCS6 G07gh4 vacuolar protein sorting 11 (yeas 177.2833 302 181.4601 P20813 I02gh6 cytochrome P450; subfamily IIB 122.3562 162 181.476 O00459 C05cd1 phosphoinositide-3-kinase; regul 145.3741 160 181.534 P50151 H24ab4 guanine nucleotide binding prote 186.5329 193 182.0963 Q16850 D12ab3 cytochrome P450; 51 (lanosterol 353.9667 116 182.1309 Q9ULW3 J09cd8 TATA-binding protein-binding pr 97.23454 207 182.1565 Q16378 O20cd7 proline rich 4 (lacrimal) 81.91 152 182.3589 P41240 J14ab4 c-src tyrosine kinase 175.1285 153 182.4257 Q16649 G05cd1 nuclear factor; interleukin 3 regul 353.6698 169 182.4266 Q9Y3M2 J03ef8 chromosome 22 open reading fr 74.27488 194 182.6022 Q9UK58 M14gh4 cyclin L ania-6a 191.3619 313 182.6351 P47874 M23cd1 olfactory marker protein 250.3691 172 182.73 O95620 O03cd7 protein similar to E. coli yhdg and 227.8932 207 183.1055 Q9UHV2 J11cd8 CDK4-binding protein p34SEI1 144.2806 163 183.5211 P02810 F07gh6 proline-rich protein HaeIII subfa 410.3478 392 183.6977 O94903 K04cd7 proline synthetase co-transcribe 242.2062 146 183.9744 Q9P0W6 I03ef4 lipopolysaccharide specific resp 149.1418 177 184.0725 Q9H8X4 O15gh5 stromal membrane-associated pr 358.1542 342 184.0879 P02786 D24ef5 transferrin receptor (p90; CD71) 320.8365 257 184.2545 E15ef1 immunoglobulin heavy constant 386.489 176 184.3533 Q99717 J01ab7 MAD; mothers against decapent 227.5817 153 184.3978 Q15036 B23gh1 sorting nexin 17. 303.8909 411 184.4831 P31751 A08ab2 v-akt murine thymoma viral onco 253.7531 253 184.8245 P11177 G21ab8 pyruvate dehydrogenase (lipoam 229.1486 150 185.0719 Q9UEQ6 F22ab2 arrestin; beta 2 190.7331 128 185.1221 Q16531 J11ab5 damage-specific DNA binding pr 205.1934 229 185.1363 P28698 G24cd3 zinc finger protein 42 (myeloid-s 76.12612 105 185.3347 P41968 N12ef4 melanocortin 3 receptor 225.3987 287 185.5363 P54920 E03cd4 N-ethylmaleimide-sensitive facto 306.753 267 185.697 Q99487 C19ab8 platelet-activating factor acetylhy 228.4138 241 185.7091 Q9H0C8 N15gh7 integrin-linked kinase-associated 120.8459 109 185.7532 P17252 F17ab8 protein kinase C; alpha 108.3851 74 185.8466 P06493 B01ef5 cell division cycle 2; G1 to S and 108.1696 76.2 185.8754 O00139 C14ab7 kinesin heavy chain member 2 140.4141 205 185.9437 P54259 N05ef6 dentatorubral-pallidoluysian atro 165.5295 152 186.0962 Q99757 G10cd8 thioredoxin 2 309.0415 163 186.106 Q9NW68 B12gh2 hypothetical protein FLJ10276 107.4044 242 186.1575 P16106 O16gh6 H3 histone family; member J 137.9914 135 186.2589 P40692 M06ef6 mutL homolog 1; colon cancer; n 98.77988 108 186.2872 Q99798 E01ab2 aconilase 2; mitochondrial 615.211 291 186.5524 P53618 A11ef3 coatomer protein complex; subu 238.4951 102 186.6268 Q9UJ69 N24gh2 Toll-interacting protein 211.4055 259 186.6408 Q9NRM2 P22ef8 zinc finger protein 277 232.9567 227 186.8854 Q92879 B06cd6 CUG triplet repeat; RNA binding 217.3752 198 187.122 O75399 H22gh1 deformed epidermal autoregulat 189.8387 266 187.2872 Q9BZE4 I17cd8 G protein-binding protein CRFG 151.2547 214 187.3094 Q9NXB2 G08gh2 hypothetical protein FLJ20343 259.0672 285 187.4246 O95424 M06ef4 MYLE protein 103.2077 184 187.5574 P54577 D14cd3 tyrosyl-tRNA synthetase 145.5748 108 187.5756 O43692 N03ef7 protease inhibitor 15 102.5299 163 187.7565 O60507 J03cd3 tyrosylprotein sulfotransferase 1 190.271 136 188.0843 Q9BYS9 B15gh5 MMS19-like (MET18 homolog; S. 99.29429 117 188.1006 P32780 G11ab6 general transcription factor IIH; p 258.9396 180 188.3175 Q14004 D07ef5 cell division cycle 2-like 5 (cholin 92.56943 158 188.3656 Q15910 L08ab5 enhancer of zeste homolog 2 (D 213.1801 306 188.8314 P47974 H22ab4 zinc finger protein 36; C3H type- 187.7102 163 188.8801 Q13177 E20ab8 p21 (CDKN1A)-activated kinase 367.7706 232 188.9048 P16gh8 baculoviral IAP repeat-containin 251.3679 126 189.0052 P98172 J01ef7 ephrin-B1 122.8828 109 189.5198 Q9BQB1 N04gh6 hypothetical protein FLJ10342 113.906 172 189.7648 O75472 H11cd5 DnaJ (Hsp40) homolog; subfamil 227.1041 204 189.9354 O75608 K06cd6 lysophospholipase I 357.6112 374 190.1833 O00193 E14ef3 small acidic protein 223.9793 284 190.2397 Q14452 B08ab5 glucocorticoid receptor DNA bin 158.8451 147 190.439 P55268 P18ef6 laminin; beta 2 (laminin S) 125.0717 152 190.5787 Q9P006 A20ef8 mitochondrial ribosomal protein 114.6952 151 190.6578 Q9Y365 P07ef1 CGI-111 protein 158.6983 176 190.6804 Q9NQ34 A10gh4 chromosome 11 open reading fr 144.3438 161 190.6944 Q9NWY4 O14gh2 hypothetical protein FLJ20534 70.02507 110 191.0561 Q9UBS8 P17ab2 ring finger protein 14 227.9827 247 191.1542 Q9UBS4 J06ef2 DnaJ (Hsp40) homolog; subfamil 181.8446 175 191.2168 Q12797 J22ab2 aspartate beta-hydroxylase 101.2251 86.5 191.3988 Q9H4I9 P10gh8 hypothetical gene supported by 167.5049 219 191.4831 O14907 E24ef8 Tax interaction protein 1 351.7729 403 191.7684 Q14673 B09gh1 Bcl-2-associated transcription fa 97.16912 117 191.9499 Q9NWB7 P01gh2 estrogen-related receptor beta li 567.7076 84.6 192.0982 Q9BVH4 G21gh6 hypothetical protein MGC3196 164.8572 169 192.4133 P22897 I17ab7 mannose receptor; C type 1 77.30638 100 192.4612 P19012 L04ab6 keratin 15 146.5632 130 192.6097 Q14738 C16cd1 protein phosphatase 2; regulator 224.4642 183 192.7984 O95152 F04cd4 vesicle trafficking protein 197.6319 196 192.9314 P78426 A09cd3 NK6 transcription factor homolog 198.5291 353 193.0203 Q14790 P14ab3 caspase 8; apoptosis-related cys 124.8603 284 193.1013 P07711 N13ab4 cathepsin L 137.16 121 193.1454 P32942 B02ab6 intercellular adhesion molecule 3 140.3673 140 193.1656 L18ab2 ATPase; Na+/K+ transporting; a 188.9371 131 194.2503 Q9NWS0 F13gh2 hypothetical protein FLJ20643 81.29108 107 194.4652 Q9NWZ5 O06gh2 uridine kinase-like 1 176.188 358 194.4782 O75792 D15cd6 ribonuclease HI; large subunit 100.3515 99.6 194.705 P05141 I04ab2 solute carrier family 25 (mitocho 454.9832 311 194.7577 Q9NX38 K22gh2 hypothetical protein FLJ20457 140.7383 161 195.2668 Q9Y682 A18cd8 sec22 homolog 193.7656 271 195.3918 P78381 C02cd4 solute carrier family 35 (UDP-gal 276.1892 207 195.6585 Q9UMP5 B23ef3 replication initiation region protei 270.4297 179 195.6957 Q9P0Q0 C15ef3 hypothetical protein HSPC226 129.6054 241 195.7376 Q9UBQ3 M12cd7 polyamine-modulated factor 1 189.4397 172 195.7465 P27540 D22ab2 aryl hydrocarbon receptor nuclea 239.4814 258 195.776 Q9Y2W1 F03cd5 thyroid hormone receptor-associ 160.2008 248 195.7775 P82267 E15ab4 adaptor-related protein complex 198.6022 231 195.7793 P00918 C16ab3 carbonic anhydrase II 283.4506 172 195.9099 Q9Y663 E07cd6 heparan sulfate (glucosamine) 3 259.052 99.8 196.1045 Q9NX40 K18gh2 ovarian carcinoma immunoreacti 119.6155 247 196.1836 P50222 L09ab7 mesenchyme homeo box 2 (grow 165.3048 223 196.5502 Q13610 C16cd7 nuclear phosphoprotein similar t 160.8948 331 196.7055 P49591 B12cd2 seryl-tRNA synthetase 152.5268 69.6 196.7944 P04554 C19gh5 protamine 3 314.8934 296 196.9835 P02538 N12ef6 keratin 6A 227.8925 277 197.1759 Q13637 G23cd7 RAB32; member RAS oncogene 392.0158 269 197.2609 P39086 J02ab3 glutamate receptor; ionotropic; k 184.3318 210 197.334 Q9H8F9 H20gh5 hypothetical protein 24432 287.08 202 197.402 Q99460 L13ab8 proteasome (prosome; macropa 298.3527 228 197.4025 Q9UKP6 D20gh1 G protein-coupled receptor 14 213.3717 142 197.5131 Q16589 A04ef5 cyclin G2 99.61434 214 197.5658 O95316 M03cd5 ribosomal protein S6 kinase; 90 k 144.8234 145 197.5662 O14545 A09cd7 FLN29 gene product 238.4292 288 197.8936 Q9Y249 P03cd6 homologous to yeast nitrogon pe 191.1146 224 198.1049 Q92794 K12cd4 zinc finger protein 220 134.123 179 198.312 P36894 A12ab3 bone morphogenetic protein rece 149.2953 236 198.4963 P79525 L21ab7 MHC class I polypeptide-related 120.8289 125 198.5782 O14947 K04ab6 laminin; beta 3 (nicein (125 kD); 360.8887 284 199.2636 Q12899 K16cd3 tripartite motif-containing 26 188.6935 250 199.2998 M24gh8 zinc finger protein 289; ID1 regul 91.37228 137 199.4969 Q9UIJ5 A18ef2 zinc finger; DHHC domain contai 436.5048 452 199.696 P46821 J11ab7 microtubule-associated protein 1 121.2356 136 199.8286 O60906 P04cd1 sphingomyelin phosphodiesteras 282.5771 281 199.835 P04040 O18ab5 catalase 160.7098 239 199.9283 O60709 B16cd5 dynamin 1-like 85.33527 220 199.9492 Q14714 A02cd4 sarcospan (Kras oncogene-asso 378.724 148 200.1413 P39687 F01cd4 acidic (leucine-rich) nuclear pho 226.8272 108 200.186 O75341 K16cd4 BRCA1 associated protein 151.895 209 200.2666 Q9NUN1 D16gh3 hypothetical protein FLJ11259 152.5767 196 200.5435 Q9UHR5 L22ef7 transcriptional regulator protein 225.1172 345 200.7483 Q9UMX3 D15gh8 BCL2-related ovarian killer 185.2616 176 200.9857 Q02297 J05ef6 neuregulin 1 89.51288 234 201.3025 Q9BQ83 A21gh6 hypothetical protein MGC5178 302.7768 398 201.3498 O43491 C22ab4 erythrocyte membrane protein b 265.5557 144 201.5208 Q92922 N16cd1 SWI/SNF related; matrix associa 251.3134 195 201.571 Q16099 J11ef3 glutamate receptor; ionotropic; k 200.0311 288 201.66 O95328 B06gh4 hypothetical protein 628 253.2751 240 201.6989 Q06265 C15cd1 polymyositis/scleroderma autoan 167.3169 182 202.2097 Q01780 K12gh6 polymyositis/scleroderma autoan 196.9508 270 202.2308 Q9NPF9 G07ef3 HeLa cyclin-dependent kinase 2 251.6953 170 202.5242 Q9P1U0 B03ef4 zinc ribbon domain containing; 1 110.7474 151 202.7351 Q13480 C02ab5 GRB2-associated binding protei 171.5634 150 203.065 O95205 O05gh1 C3H-type zinc finger protein; sim 138.7838 267 203.3797 O76091 I11cd1 nitrilase 1 194.24 179 203.4317 Q9Y364 F21ef2 DKFZP434J154 protein 208.15 322 203.5516 P51116 I14cd5 fragile × mental retardation; auto 215.9784 213 203.6388 P49915 H19cd4 guanine monphosphate syntheta 175.5001 115 203.6534 Q9UHR3 O04cd8 nasopharyngeal carcinoma susc 120.0173 196 203.8212 Q15007 O10cd5 Wilms' tumour 1-associating prot 237.1077 258 204.228 P24941 B03ef5 cyclin-dependent kinase 2 98.60804 214 204.3554 P53634 L01ef7 cathepsin C 97.3314 77.9 204.771 Q13123 K03ef7 IK cytokine; down-regulator of H 108.6134 153 204.9565 Q9NUT6 P21gh3 hypothetical protein FLJ11151 285.3106 565 205.0219 Q9Y279 B23cd7 Ig superfamily protein 356.8489 226 205.0366 O75319 H07cd3 dual specificity phosphatase 11 250.2151 205 205.1456 Q9NYH9 L08ef3 hepatocellular carcinoma-associ 287.2586 283 205.223 Q9UNF0 M20cd7 protein kinase C and casein kina 438.5503 349 205.53 O60437 D03ab8 periplakin 443.9882 301 205.5879 Q9NZN8 N22cd8 CCR4-NOT transcription comple 189.665 224 205.673 Q14232 A18ab4 eukaryotic translation initiation fa 273.7271 210 205.7436 O00142 C03ef5 thymidine kinase 2; mitochondria 124.7128 147 205.9951 O60443 N15ab5 deafness; autosomal dominant 5 122.4035 264 206.3187 O95406 J20cd5 cornichon-like 181.7181 138 206.4442 Q12841 E24cd7 follistatin-like 1 80.93058 97.7 206.5097 O15217 B04ab5 glutathione S-transferase A4 78.38055 91.3 206.6118 P10645 E01ab4 chromogranin A (parathyroid sec 115.7467 283 206.8714 Q9HA66 D09gh5 G protein beta subunit-like 198.1992 192 206.9573 Q9Y439 B06ef8 PRP31 pre-mRNA processing fa 175.7234 310 207.0904 Q9Y386 G08ef2 CGI-78 protein 325.6509 246 207.7702 P53990 D21gh1 KIAA0174 gene product 230.1187 401 207.9831 O95865 O11ef3 dimethylarginine dimethylaminoh 125.0105 157 208.0048 B21ef1 immunoglobulin lambda-like poly 142.7367 230 208.1338 Q15834 I17cd7 hepatitis delta antigen-interactin 320.7647 226 208.1753 P18846 H05ab4 activating transcription factor 1 470.9776 206 208.3404 Q14349 A23cd7 HLA-B associated transcript 8 138.8938 175 208.5984 Q9NVM5 M08gh3 hypothetical protein FLJ10637 98.19923 115 209.0315 P12955 N18ab7 peptidase D 133.8157 192 209.0325 Q99700 D14cd1 spinocerebellar ataxia 2 (olivopo 191.0044 240 209.0555 Q9UJA2 E21gh3 chromosome 20 open reading fra 134.2553 316 209.227 Q02246 J21ef6 contactin 2 (axonal) 108.0043 68.8 209.3915 P48553 E06cd2 transmembrane protein 1 148.0375 238 209.4168 Q99639 K03cd2 suppressor of Ty 5 homolog (S. 225.1962 296 209.795 Q9NQX5 N02gh4 neural proliferation; differentiatio 188.0695 206 209.8245 Q99799 O08cd6 nuclear RNA export factor 1 205.4132 175 209.9237 Q9BZV1 J05gh7 UBX domain-containing 1 127.7069 236 209.9733 Q03113 M19ab5 guanine nucleotide binding prote 140.2412 112 209.9975 P01130 B21ab6 low density lipoprotein receptor ( 301.1179 394 210.369 Q9UHN6 L11cd8 transmembrane protein 2 182.3012 130 210.5088 Q99738 A03cd3 pinin; desmosome associated pr 200.7164 204 210.6944 Q9Y576 N03ef2 ankyrin repeat and SOCS box-cc 121.1139 76.2 210.8606 P02304 B03gh6 H4 histone; family 2 81.15302 191 210.8651 P01118 I08ab7 v-Ki-ras2 Kirsten rat sarcoma 2 v 209.4177 239 211.0234 P15924 K13ef7 desmoplakin (DPI; DPII) 249.9083 263 211.0334 O43597 A19cd6 sprouty homolog 2 (Drosophila) 119.5051 155 211.0573 P09622 I06ab3 dihydrolipoamide dehydrogenas 346.3029 232 211.1679 Q08257 G16ef7 crystallin; zeta (quinone reducta 514.6998 301 211.6448 Q9UHY8 J09cd7 fasciculation and elongation pro 86.8735 95.1 211.8371 P10646 P23cd2 tissue factor pathway inhibitor (li 596.8869 458 212.0146 Q92685 L08cd5 Not56 (D. melanogaster)-like pro 195.2017 217 212.2397 P34949 I13ab7 mannose phosphate isomerase 102.2281 135 212.3424 Q9NPE9 M21ef8 HSPC055 protein 91.56792 157 212.3544 Q99853 J24ef7 forkhead box B1 141.4272 105 212.4773 Q9HD41 C24gh4 CHMP1.5 protein 280.2988 230 212.8608 Q16625 A10ab8 occludin 859.5688 338 212.9222 P45973 L18ef6 chromobox homolog 5 (HP1 alph 164.9514 124 213.1315 Q9NVI9 O12gh3 hypothetical protein FLJ10707 136.0971 136 213.1484 P37173 O09ef7 transforming growth factor; beta 112.4415 208 213.3211 Q9UKF7 O21cd8 retinal degeneration B beta 333.6061 287 213.5389 P16870 J23ef7 carboxypeptidase E 81.85341 137 213.5973 P00374 D16ab3 dihydrofolate reductase 148.8142 59.6 213.6217 P19957 M04ab8 protease inhibitor 3; skin-dervied 202.9357 582 213.9068 O75962 J24cd2 triple functional domain (PTPRF 233.7849 197 213.9409 P16050 C24ab2 arachidonate 15-lipoxygenase 288.5504 87.3 213.9824 Q9Y3D2 N14cd7 pilin-like transcription factor 200.9397 224 214.0069 O00505 J16ab6 karyopherin alpha 3 (importin alp 358.8945 313 214.0819 Q9NZD8 N15ef1 acid cluster protein 33 222.816 223 214.2958 P46937 G10cd6 Yes-associated protein 1; 65 kD 219.0427 268 214.3846 P53384 O05ab7 nucleotide binding protein 1 (Min 272.4995 223 214.5051 Q9UI28 K10ef4 AD-003 protein 120.4834 147 214.7067 Q14651 O20ab8 plastin 1 (I isoform) 517.7448 303 214.7993 P10914 K01ef6 interferon regulatory factor 1 310.699 395 214.9514 P21281 A03ab3 ATPase; H+ transporting; lysoso 299.07 638 215.0012 P53701 G19ab6 holocytochrome c synthase (cyto 251.8825 415 215.1177 Q9Y2B1 C18ef3 transmembrane protein 5 103.4737 123 215.2492 Q14166 D23ef8 KIAA0153 protein 332.5834 276 215.4465 Q15738 B09ef4 NAD(P) dependent steroid dehy 253.061 171 215.5558 Q16586 I06cd1 sarcoglycan; alpha (50 kD dystro 358.221 129 215.8058 Q9Y6J8 L05ef2 map kinase phosphatase-like pr 275.0054 326 215.9987 Q9H5F2 P17gh5 hypothetical protein FLJ23499 204.1242 332 216.1178 Q05655 E02cd1 protein kinase C; delta 419.7056 297 216.1184 Q9NXU7 M03gh3 hypothetical protein FLJ20048 240.4802 235 216.1338 O15498 P21cd6 SNARE protein Ykt6 188.9561 242 216.7243 Q92664 F07ab4 general transcription factor IIIA 318.1862 193 216.7575 Q9Y223 N03cd5 UDP-N-acetylglucosamine-2-epi 207.311 295 217.1156 O95816 E21ab3 BCL2-associated athanogene 2 84.7224 94.2 217.4827 Q9H0K5 A21gh8 hypothetical protein DKFZp434H 193.1934 324 217.6924 Q9BTJ1 C03ef2 ribosomal protein S27-like 132.1497 411 218.2702 Q9NRR5 J23gh4 chromosome 1 open reading fra 138.2192 201 218.4149 Q9Y5L3 A13ab4 ectonucleoside triphosphate dip 235.2745 316 218.4547 O75351 K06cd5 suppressor of K+ transport defec 274.5936 311 218.6389 O75443 F07cd2 tectorin alpha 183.4591 150 218.7282 Q9H7X4 K04gh7 KIAA1085 protein 268.2576 372 218.7527 O00255 K22ab6 multiple endocrine neoplasia I 134.7209 117 218.9335 Q9BV94 D05gh3 chromosome 20 open reading fr 319.259 316 219.2324 O14813 D10ab2 aristaless homeobox (Drosophila 226.3067 320 219.2567 P35269 D15ab4 general transcription factor IIF; p 243.8395 213 219.8975 Q12891 E08ef5 hyaluronoglucosaminidase 2 331.3833 311 220.4462 O15162 L08gh1 phospholipid scramblase 1 440.6448 597 220.6688 Q14469 O08ab7 hairy homolog (Drosophila) 151.2148 251 221.0242 P06241 P13ab4 FYN oncogene related to SRC; 106.4214 82.5 221.2951 Q9BVG9 P17gh7 phosphatidylserine synthase 2 225.5812 200 221.5588 Q9P0P9 K12ef2 hypothetical protein LOC51249 290.4444 434 222.6323 Q9UMF9 L14cd3 eukaryotic translation initiation fa 207.6515 242 222.6344 Q03527 L07ab8 proteasome (prosome; macropai 441.6371 284 222.6794 P31153 J15ab7 methionine adenosyltransferase 245.2111 134 222.7802 Q04741 D21ef1 empty spiracles homolog 1 (Dros 240.3769 189 222.791 Q13153 L22ef5 p21/Cdc42/Rac1-activated kinas 243.198 277 222.8583 Q9Y388 H15ef2 CGI-79 protein 100.7214 181 223.2467 Q9HC14 K17gh5 mitochondrial ribosomal protein 158.7783 200 223.2594 P30281 O08ef5 cyclin D3 107.4859 167 223.2751 Q9UFK2 P05ef8 DKFZP564K1964 protein 133.0476 210 223.4229 Q13011 O23ab4 enoyl Coenzyme A hydratase 1; 337.9818 273 223.7187 P09601 E20ef7 heme oxygenase (decycling) 1 186.4519 425 223.7447 Q9BVZ8 P23gh8 hypothetical protein FLJ14936 126.689 127 224.0692 Q13889 A11ab5 general transcription factor IIH; p 112.1935 202 224.1653 P49703 P23ab2 ADP-ribosylation factor 4-like 125.6732 91.2 224.1896 Q9GZU7 G11gh4 nuclear LIM interactor-interactin 305.5546 150 224.2596 P10253 M22ab3 glucosidase; alpha; acid (Pompe 187.3998 156 224.2782 Q9Y3V5 B18ef8 hypothetical protein DKFZP586F 303.8477 426 224.4103 O14773 P17ef7 ceroid-lipofuscinosis; neuronal 2 169.6468 214 224.4535 P22061 G13cd1 protein-L-isoaspartate (D-aspart 118.1783 163 224.5569 P14868 K21ab4 aspartyl-tRNA synthetase 117.1946 78.1 225.0996 Q14938 D16ef6 nuclear factor I/X (CCAAT-bindin 94.58773 84.9 225.3458 O75968 P21ef3 pannexin 1 215.9189 216 225.5368 Q9H779 C15gh6 hypothetical protein MGC2821 138.4597 313 225.8086 Q9BX72 C02gh8 IFP38 168.9682 172 225.8249 O43563 G24cd1 solute carrier family 22 (organic 133.7352 149 225.8428 O15142 D17ab2 ARP2 actin-related protein 2 ho 250.3086 215 226.0552 Q9UJ41 K17ef4 putative Rab5 GDP/GTP exchan 121.9096 165 226.5205 P05231 F21ef7 interleukin 6 (interferon; beta 2) 240.2349 673 226.529 Q9Y2H0 G24ef8 KIAA0964 protein 279.6086 310 226.545 Q9UJT9 E15cd8 F-box and leucine-rich repeat pr 287.9128 294 226.762 Q9Y306 O23ef2 pelota homolog (Drosophila) 146.8037 190 226.8083 Q9Y6A6 N04ef3 transcription factor (p38 interacti 174.5425 171 226.9539 O75300 K18cd2 ribosome binding protein 1 homo 98.67954 73.7 227.0651 P51798 L03ef1 chloride channel 7 278.4282 282 228.319 Q14839 C21ab4 chromodomain helicase DNA bin 104.8847 161 228.322 O60299 O18gh1 KIAA0552 gene product 132.5981 337 228.426 Q9Y6F1 H03ab2 ADP-ribosyltransferase (NAD+; 248.9844 399 228.5355 O15212 E04ef3 HLA class II region expressed g 250.113 292 228.5629 Q9Y2W2 J14ef2 WW domain binding protein 11 335.0512 304 228.6314 Q9UKN5 O03cd8 PR domain containing 4 252.6208 80.6 228.639 Q00978 C24cd6 interferon-stimulated transcriptio 303.7171 404 228.7768 Q9UHY0 L08ef1 HP1-BP74 295.9512 267 228.8435 Q9Y248 L13ef2 HSPC037 protein 92.39515 70.3 229.0541 O96019 E21ab2 BAF53 228.9673 345 229.5696 P10276 K19ab8 retinoic acid receptor; alpha 250.0312 122 229.7466 Q9BUC7 P22gh8 hypothetical protein MGC4172 136.4413 398 229.8471 Q9HAC1 D01gh5 praja 1 143.4188 97.5 230.0154 Q93078 M18gh6 H2B histone family; member H 179.9656 203 230.2553 P08572 N22ef6 collagen; type IV; alpha 2 70.14126 87.3 230.3868 P15056 G10ef5 v-raf murine sarcoma viral oncog 194.1803 174 231.0687 Q15543 J15cd2 TAF13 RNA polymerase II; TAT 222.3129 262 231.2695 O14901 J05cd3 TGFB inducible early growth res 277.9069 277 231.5821 N10gh8 diphosphate dimethylallyl diphos 313.8915 257 231.841 P51965 O13cd3 ubiquitin-conjugating enzyme E2 254.2693 673 232.1178 Q9Y3R2 G04cd8 transportin-SR 338.45 219 232.2301 O94829 G10gh1 importin 13 160.8646 247 232.3109 Q92859 M13ab8 neogenin homolog 1 (chicken) 153.0455 249 232.6926 Q12846 O02cd2 syntaxin 4A (placental) 323.5547 93.2 232.9973 P01286 G15ef1 growth hormone releasing hormo 237.6384 263 233.028 Q9UH92 L01cd8 transcription factor-like 4 172.7135 195 233.1639 O75323 P09ab5 glioblastoma amplified sequence 178.3893 168 233.5843 Q9UQ33 P07ef2 microtubule-associated protein; 101.7866 134 234.2195 Q9Y3A7 A17ef2 CGI-101 protein 402.1639 210 234.3057 Q9Y2Z0 A17cd7 suppressor of G2 allele of SKP1; 184.6693 256 234.3223 P56211 F16ab2 cyclic AMP phosphoprotein; 19 k 276.9734 386 234.3401 P21127 O13ef1 cell division cycle 2-like 2 159.1108 304 234.454 Q07866 B23ab7 kinesin 2 (60-70 kD) 254.5932 408 234.5156 Q9BTI3 H11ef8 KIAA1068 protein 228.7025 230 234.5211 Q9H2J4 E11gh6 hypothetical protein MGC3062 238.7573 256 235.0353 Q9NXE5 E10gh2 hypothetical protein FLJ20296 193.8379 399 235.1468 Q92572 E17ab4 adaptor-related protein complex: 86.23952 209 235.2813 Q9NXT6 K05gh2 FtsJ homolog 3 (E. coli) 254.7485 277 235.4026 O15321 F05cd6 transmembrane 9 superfamily m 295.1129 227 235.695 O15383 F07cd6 HIV-1 Tat interactive protein 2; 3 402.8554 444 235.7849 O60403 B06cd8 olfactory receptor; family 10; sub 237.7465 262 235.906 P49354 K24ab4 famesyltransferase; CAAX box; 173.9344 193 235.9155 P48039 B07ef6 melatonin receptor 1A 305.0267 208 236.1249 O43562 C08ab8 solute carrier family 22 (organic 115.4101 125 236.1587 Q9HC89 N24ef8 calpain 10 212.0136 242 236.247 P00790 M13ef1 pepsinogen 5; group I (pepsinog 256.009 266 236.6918 Q9NVP1 G01cd6 DEAD/H (Asp-Glu-Ala-Asp/His) 78.40555 89 236.7778 Q9UBN1 F23ef3 calcium channel; voltage-depend 269.9719 360 237.0557 P35659 M22cd3 DEK oncogene (DNA binding) 80.02159 77.8 237.1934 P54252 N09ef6 Machado-Joseph disease (spino 156.7549 274 237.2775 Q14152 L12cd3 eukaryotic translation initiation fa 364.5131 268 237.302 Q9Y314 E16ef2 eNOS interacting protein 123.3313 219 237.3058 Q9NRC7 E23ef3 sirtuin silent mating type informa 136.0486 328 237.5194 P02533 N02ef6 keratin 14 (epidermolysis bullosa 203.4102 190 237.6951 O60907 J19cd2 transducin (beta)-like 1 X-linked 175.9553 171 237.7396 P43155 B16ab3 carnitine acetyltransferase 288.355 190 237.8908 Q15077 H08ab8 pyrimidinergic receptor P2Y; G-p 389.9746 248 238.1475 Q12840 I06ab7 kinesin family member 5A 238.3605 282 238.2407 P26599 A05cd3 polypyrimidine tract binding prot 160.4912 345 238.4 Q9Y316 M11ef2 C21orf19-like protein 450.6398 327 238.5981 P24394 O18ab6 interleukin 4 receptor 309.5199 330 238.6201 P32418 J22gh1 solute carrier family 8 (sodium/c 171.4835 134 238.7225 P42694 N01ef3 helicase with zinc finger domain 165.7017 146 238.7561 O60755 L09cd3 galanin receptor 3 162.6185 268 238.7669 Q16204 A18cd4 DNA segment; single copy; prob 192.0586 225 238.8166 Q12980 N15cd7 Conserved gene telomeric to alp 183.7714 174 238.9231 P08559 N16ab7 pyruvate dehydrogenase (lipoam 375.1479 206 239.4879 Q9Y2U9 K02ef3 host cell factor homolog 127.5142 154 239.623 Q9Y2T2 P17cd7 adaptor-related protein complex: 336.9686 395 239.6299 Q13105 K10cd3 zinc finger protein 151 (pHZ-67) 177.9188 243 240.018 Q9H1J1 J12gh5 similar to yeast Upf3; variant A 154.12 183 241.0316 Q08752 E01cd1 peptidylprolyl isomerase D (cycl 446.371 203 241.0389 P38159 F14ab7 RNA binding motif protein; X ch 342.4693 176 241.0429 Q9Y337 A12cd8 kallikrein 5 215.5515 312 241.2144 P25445 A02ef6 tumor necrosis factor receptor su 102.3524 215 241.2257 Q9BZH1 P02gh5 membrane-spanning 4-domains; 350.8825 212 241.5154 O43633 O12ef4 putative breast adenocarcinoma 308.4601 232 241.573 Q99536 B03cd6 vesicle amine transport protein 1 222.8504 400 241.6698 P24557 N11cd1 thromboxane A synthase 1 (plat 326.4482 236 241.6841 O75369 G16ab4 filamin B; beta (actin binding pro 331.6975 459 241.7672 P50453 H10ab8 serine (or cysteine) proteinase in 439.8605 370 242.4005 P35680 O18cd1 transcription factor 2; hepatic; LF 235.5021 174 242.5943 Q03924 I01gh7 zinc finger protein 117 (HPF9) 257.8571 301 242.7729 Q9NRQ5 F17gh4 FN5 protein 361.924 325 242.8257 Q99867 G12gh7 tubulin; beta polypeptide 4; mem 376.7361 247 243.6773 Q9H682 B19gh7 A20-binding inhibitor of NF-kapp 205.6095 365 243.7949 O00148 N12cd5 DEAD/H (Asp-Glu-Ala-Asp/His) 259.196 140 244.0023 F11cd8 TCF3 (E2A) fusion partner (in ch 170.7519 295 244.0153 Q9UG51 N05ef3 anaphase-promoting complex su 274.4079 331 244.0324 O75175 F12cd8 CCR4-NOT transcription comple 230.1579 253 244.0384 Q9GZQ8 C05gh2 microtubule-associated proteins 261.5987 395 244.0725 P19438 A04ef6 tumor necrosis factor receptor su 233.3188 197 244.3384 Q9NRR8 O04gh4 small protein effector 1 of Cdc42 338.2133 329 244.5729 O95162 N10ef8 peroxisomal short-chain alcohol 154.9486 108 244.9155 O95279 J22cd3 potassium channel; subfamily K; 274.3417 127 244.9972 Q9NTW4 N21ef8 DKFZP564A2416 protein 403.4188 219 245.1953 Q9NWM9 H21gh2 hypothetical protein FLJ20730 121.538 207 245.69 P40121 P23ab5 capping protein (actin filament); 452.2006 414 245.8846 Q92466 I04ab3 damage-specific DNA binding p 99.17314 220 246.0478 O43365 K05gh7 homeo box A3 132.7369 196 246.2071 Q9NVJ7 O02gh3 DEAD/H (Asp-Glu-Ala-Asp/His) 336.1927 284 246.3831 Q9NVY5 H08ef7 serologically defined colon canc 182.4596 178 246.7633 Q9BY40 G12gh8 CDA11 protein 141.0763 131 246.8975 Q9NZE2 O06ef2 hypothetical protein LOC51321 76.41026 135 247.0025 P29275 K11ab2 adenosine A2b receptor 354.5115 191 247.0615 Q9NZE0 P22ef1 WW domain-containing adapter 82.72809 71.1 247.6094 Q03111 N03ab7 myeloid/lymphoid or mixed-linea 225.1377 162 247.8275 Q08499 G21ef6 phosphodiesterase 4D; cAMP-sp 125.5177 92.9 248.1727 Q15628 A20ef6 TNFRSF1A-associated via death 214.1641 250 248.2613 Q9Y657 C07cd7 spindlin 217.9487 202 248.4185 Q9UHQ1 I09cd8 nuclear prelamin A recognition f 312.9614 303 248.5926 P17980 H24ef6 proteasome (prosome; macropai 331.1488 193 248.6286 P45877 I19ab8 peptidylprolyl isomerase C (cycl 165.0716 169 248.9851 O95340 A23cd5 3′-phosphoadenosine 5′-phosph 110.9876 88.6 249.0622 Q9H9Z7 F18gh5 hypothetical protein FLJ12448 158.5794 279 249.1478 O15172 E11cd4 phosphoserine phosphatase-like 321.9068 291 249.3629 P01298 F05ab8 pancreatic polypeptide 544.0034 194 249.376 Q13395 J17cd2 TAR (HIV) RNA binding protein 1 260.7056 234 249.3777 O15551 G23ab4 claudin 3 279.9519 250 249.4618 P55060 G20ef6 CSE1 chromosome segregation 322.1588 276 249.5903 O43286 E13ab3 UDP-Gal: betaGlcNAc beta 1; 4- 316.581 468 249.8072 P04424 J10ab2 argininosuccinate lyase 594.9833 269 250.046 Q9NWR5 C10gh3 hypothetical protein FLJ20657 171.9643 252 250.1961 Q9BUN8 M21gh6 hypothetical protein MGC3067 165.6904 175 250.2847 P49760 G01ab4 CDC-like kinase 2 69.23701 97.1 250.3266 Q9UEG3 E01gh7 myotubularin related protein 3 367.623 236 250.553 Q9P0Y6 N07ef1 chromosome 3 open reading frar 268.1158 256 250.6098 Q92535 M06ab8 phosphatidylinositol glycan; clas 218.2502 172 250.9192 Q00577 A24gh7 purine-rich element binding prot 839.6 273 251.0214 O75717 L21ab2 AND-1 protein 225.9974 250 251.1522 P04278 L09cd1 sex hormone-binding globulin 215.6067 196 251.1944 P51124 G19ab5 granzyme M (lymphocyte met-as 108.9072 114 251.2498 P15259 P04ab7 phosphoglycerate mutase 2 (mu 333.2442 363 251.6606 Q12893 O13cd7 PL6 protein 174.3077 280 252.0241 P57738 A11gh2 T-cell leukemia transiocation aite 166.5683 232 252.2165 P24863 O22ef5 cyclin C 668.8634 523 252.3632 Q9Y370 H03ef2 CGI-60 protein 153.6349 157 252.5036 Q9HD89 E04gh4 found in inflammatory zone 3 189.8748 182 252.7224 O14807 N04cd7 muscle RAS oncogene homolog 105.1243 181 252.8147 Q13435 I07cd7 splicing factor 3b; subunit 2; 145 270.3354 268 252.8473 Q9UMY4 F19cd8 sorting nexin 12 178.8659 227 253.0136 O43929 C04ab8 origin recognition complex; subu 267.5605 354 253.265 Q9BZQ1 H14gh7 chromosome 1 open reading frar 219.6632 362 253.5183 P55042 K03ef5 Ras-related associated with diab 300.5794 514 253.5279 Q92870 k18ef1 amyloid beta (A4) precursor prot 76.07104 77.9 253.5714 P33778 C19gh7 H2B histone family; member F 169.4431 391 253.9554 Q9ULZ3 K22cd8 apoptosis-associated speck-like 255.9554 517 254.0856 Q13485 A20ef5 MAD; mothers against decapent 163.1373 181 254.1546 Q9H684 C24gh5 zinc finger protein 335 326.6826 261 254.3385 Q9H7F8 O06gh7 hypothetical protein FLJ20958 190.1073 258 254.7196 Q92508 B17gh1 KIAA0233 gene product 241.1859 216 255.0491 Q9UM47 C15ab8 Notch homolog 3 (Drosophila) 64.97745 132 255.0839 P18084 E17ef7 integrin; beta 5 259.2818 129 255.1335 Q99462 K22gh6 ubiquitin-conjugating enzyme E2 207.6691 179 255.2632 O75619 J10ef7 RNA helicase-related protein 198.1059 335 255.6713 Q92733 K07cd1 papillary renal cell carcinoma (tr 200.3207 260 256.1407 Q15796 H21ab7 MAD; mothers against decapent 376.8422 446 256.2171 P15291 E07ab3 UDP-Gal: betaGlcNAc beta 1; 4- 411.9325 403 256.9006 Q99417 I07cd8 c-myc binding protein 264.1386 256 256.9088 P06732 D09ab4 creatine kinase; muscle 202.527 127 257.2272 P50570 K13ab5 dynamin 2 248.1389 228 257.2474 Q9Y5A9 F20ef2 high-glucose-regulated protein 8 359.385 371 257.3917 Q92841 B17cd6 DEAD/H (Asp-Glu-Ala-Asp/His) t 229.8916 270 257.9255 P51808 B22cd2 t-complex-associated-testis-exp 182.2992 245 257.9487 O95758 H23cd5 ROD1 regulator of differentiation 411.9888 462 258.1758 P32970 I15ef5 tumor necrosis factor (ligand) su 443.4158 456 258.4229 O75689 K21cd7 centaurin; alpha 1 191.7263 327 258.6362 P55072 O06cd4 valosin-containing protein 466.7034 363 258.8411 P47813 A16ab4 eukaryotic translation initiation fa 486.6493 337 259.0481 Q15532 J03cd2 synovial sarcoma translocation; 190.8535 212 259.1488 Q15813 M19cd2 tubulin-specific chaperone 151.2337 166 259.2747 P14373 B08cd2 ret finger protein 282.5757 270 259.3599 O14980 G02cd3 exportin 1 (CRM1 homolog; yeas 239.4965 207 259.7187 P07942 P20ef6 laminin; beta 1 71.03574 92.4 259.7579 P53041 C20cd1 protein phosphatase 5; catalytic 272.5094 196 259.8136 Q07820 E12ef6 myeloid cell leukemia sequence 362.5007 243 260.0329 P53816 E04cd7 HRAS-like suppressor 3 606.0957 558 260.1565 Q9P1C8 E09gh4 hypothetical protein PRO2577 238.9909 205 260.3147 P51966 O21cd3 ubiquitin-conjugating enzyme E2 148.3528 243 260.3185 Q99739 M03cd7 plm-2 oncogene 178.694 274 260.4482 P35913 N14ab7 phosphodiesterase 6B; cGMP-s 199.3654 173 260.5708 P52756 J24cd5 RNA binding motif protein 5 280.6537 230 261.0637 Q9NXX5 K17gh3 hypothetical protein FLJ20004 130.163 197 261.2642 Q14498 O06cd5 RNA-binding region (RNP1; RR 196.0463 216 261.5829 P28069 A03ab8 POU domain; class 1; transcripti 261.1822 206 261.7763 P51397 E20ab5 death-associated protein 348.1009 312 261.9342 Q9NUI8 C24gh7 putative methyltransferase 157.3551 329 262.0287 O00322 M09cd7 uroplakin 1A 223.5286 295 262.0828 P78368 I09ab4 casein kinase 1; gamma 2 211.1048 272 262.1137 Q01081 I22cd4 U2(RNU2) small nuclear RNA au 138.1533 91.3 262.1811 O43193 J15ab5 G protein-coupled receptor 38 69.57316 206 262.301 Q9Y3B0 M03ef2 CGI-105 protein 174.5026 177 262.5458 Q9NV80 H05gh3 WD repeat domain 12 178.5139 279 262.6286 Q9Y473 O18cd4 zinc finger protein 175 141.3794 275 263.1099 Q9Y548 L20gh2 hypothetical protein DJ167A19.1 233.5442 240 263.4412 Q13952 N15ef6 nuclear transcription factor Y; ga 241.7469 354 263.6055 P18615 K17cd3 RD RNA-binding protein 237.0199 242 263.7642 P33241 B23ef1 lymphocyte-specific protein 1 94.80267 131 264.242 O15116 C01ef4 Lsm1 protein 344.8146 479 264.6979 P50897 A11ab8 palmitoyl-protein thioesterase 1 ( 126.6311 142 264.8236 F20gh8 MADP-1 protein 134.6124 228 264.9564 Q9Y3A5 G12ef2 CGI-97 protein 469.4567 544 265.0744 Q9BVT1 G03gh6 leukocyte receptor cluster (LRC) 282.5457 328 265.5443 Q9UM44 E10cd7 HERV-H LTR-associating 2 180.7238 119 265.5625 Q9UGC7 A05gh3 similar to prokaryotic-type Class I 289.9756 362 265.7778 P49146 G01ab8 neuropeptide Y receptor Y2 222.0084 57.8 265.9266 P54687 I03ab3 branched chain aminotransferas 103.4218 93.8 266.0547 O60884 O09cd6 DnaJ (Hsp40) homolog; subfamil 330.3137 367 266.0819 Q9NVC6 J01cd7 cofactor required for Sp1 transcri 183.0562 150 266.1556 O43399 G06cd2 tumor protein D52-like 2 283.4636 348 266.2168 O75880 K22cd2 SCO cytochrome oxidase deficie 156.7184 117 266.2419 P49406 F01gh1 mitochondrial ribosomal protein 577.0339 353 266.3918 Q9NYK5 E15gh2 mitochondrial ribosomal protein 473.2712 449 266.7642 O15428 P18cd2 protein (peptidyl-prolyl cis/trans 185.1313 249 267.1449 O14842 K04ab5 G protein-coupled receptor 40 222.6002 170 267.4241 O15262 I06cd6 ring finger protein 3 243.845 401 267.4275 Q9NP61 J01ef3 ADP-ribosylation factor GTPase 344.6989 175 267.443 O15491 P22cd5 WD-repeat protein 254.6166 355 267.6951 O75390 P01ab5 citrate synthase 656.561 312 268.0488 P57088 I12gh3 hypothetical protein FLJ10525 377.5067 349 268.1833 Q9NRY6 K06gh4 phospholipid scramblase 3 272.0774 334 268.2248 O15403 E05cd5 solute carrier family 16 (monocar 384.2992 73.5 268.3423 Q9BPZ5 K09gh6 hypothetical protein MGC3123 127.3745 286 268.7928 P10301 P01cd2 related RAS viral (r-ras) oncoger 314.4978 204 268.8367 A20gh7 HLA-B associated transcript 4 168.0802 234 269.0656 Q9P018 A08ef8 HSPC142 protein 196.1899 346 269.5447 Q9Y4H2 L10cd3 insulin receptor substrate 2 297.029 329 270.4962 Q9UJX3 F04ef2 anaphase-promoting complex su 210.2906 204 270.642 Q9H5X0 O01gh6 hypothetical protein MGC2941 333.5834 308 270.759 Q92820 H23cd4 gamma-glutamyl hydrolase (conj 78.13783 101 271.925 Q9UKK3 K15ab2 ADP-ribosyltransferase (NAD+; 337.297 450 271.9944 Q9NWC8 N13gh2 hypothetical protein FLJ10120 315.7654 301 272.0013 O14965 I07cd2 serine/threonine kinase 6 139.2727 101 272.158 P50613 B11ef5 cyclin-dependent kinase 7 (MO1 286.8535 423 272.2018 Q9H1C4 H08gh7 unc-93 homolog B1 (C. elegans) 348.8713 501 272.3385 P21851 E13ab4 adaptor-related protein complex 338.7753 373 272.4617 Q9UGJ0 B14ef2 protein kinase; AMP-activated; g 425.3015 543 272.5312 P04035 D17ab6 3-hydroxy-3-methylglutaryl-Coen 242.9132 169 273.2324 Q9UKY7 K03gh3 hypothetical protein H41 643.0085 272 273.736 O95478 B18gh1 hypothetical protein YR-29 248.2059 221 273.8047 Q9Y3W9 B16ef8 sentrin/SUMO-specific protease 220.4064 333 274.1753 Q9Y325 A20ef2 CGI-36 protein 346.618 338 274.2434 Q92854 B09cd6 sema domain; immunoglobulin d 342.6474 183 274.4146 P16106 O08gh6 H3 histone family; member C 105.4744 221 274.8424 O43143 M05ab4 DEAD/H (Asp-Glu-Ala-Asp/His) 412.7015 349 274.9731 Q13547 L12ef6 histone deacetylase 1 375.5725 372 275.2293 Q9H6F9 D11gh5 hypothetical protein FLJ22313 306.5811 290 275.269 O9NX18 M08gh2 hypothetical protein FLJ20487 311.71 394 275.6418 O94764 P03cd5 RAN binding protein 9 256.3223 268 275.8144 P82909 N18gh8 mitochondrial ribosomal protein 261.4618 343 275.8463 Q9UI07 D18ef8 likely ortholog of mouse heal sh 199.8914 199 276.061 P20337 M01ef5 RAB3B; member RAS oncogene 214.8304 126 276.148 Q07960 B22ab2 Rho GTPase activating protein 219.98 218 276.184 P49448 P03cd7 Glutamate dehydrogenase-2 344.3683 229 276.2751 Q9NX48 K08gh2 hypothetical protein FLJ20442 493.7568 601 276.8343 Q9NV56 J03gh3 chromosome 20 open reading fr 138.9543 104 277.4945 O00154 L21cd7 brain acyl-CoA hydrolase 173.5669 189 277.5737 Q9UI70 B04ef1 nucleolar protein ANKT 307.7657 349 277.6076 P26045 N17ab8 protein tyrosine phosphatase; no 412.292 315 277.6603 Q9Y2A8 C24ef3 CD209 antigen-like 72.21222 91.3 277.8103 Q9BZ89 F08gh7 phospholipase A2; group XII 175.384 216 277.9804 P35052 J24ab4 glypican 1 214.4355 173 278.2085 Q9H0S9 K21gh7 nuclear receptor binding factor-2 80.19669 155 278.4321 Q15654 I07ef7 thyroid hormone receptor interac 264.295 238 278.8016 P51948 I09ab7 menage a trois 1 (CAK assembly 239.1769 272 278.9368 Q13133 B20cd5 nuclear receptor subfamily 1; gro 276.5554 260 279.1408 Q9P0J9 H22gh3 goliath protein 337.3229 215 279.5646 Q15546 G23cd8 monocyte to macrophage differe 136.5038 94 279.6415 P28325 E09ab5 cystatin D 371.6792 309 279.7092 O94985 O04ef8 calsyntenin 1 137.0471 205 279.921 P48634 M03cd4 HLA-B associated transcript 2 266.8369 179 280.5497 Q9BRL6 O15gh7 Splicing factor; arginine/serine- 220.3804 304 280.5881 O94851 E06gh1 KIAA0750 gene product 108.6672 172 280.9738 Q9NW56 E20gh3 hypothetical protein FLJ10305 240.4538 314 281.002 Q9H6X6 P19gh5 CasL interacting molecule 183.3739 302 281.185 P41217 N13ab7 antigen identified by monoclonal 325.1642 166 281.3505 P31512 P04ab4 flavin containing monooxygenas 192.4074 276 281.6555 Q15425 H05cd2 SA hypertension-associated hor 186.2788 151 281.9205 P40306 L05ab8 proteasome (prosome; macropai 408.3043 513 281.9429 Q9NWZ8 O02gh2 hypothetical protein FLJ20514 287.569 146 281.9498 P57073 E22ef8 SRY (sex determining region Y) 202.5886 268 281.9705 Q9Y450 H22cd6 HBS1-like (S. cerevisiae) 230.8266 312 282.4288 P04062 O08ab3 glucosidase; beta; acid (includes 295.5318 389 282.6453 O75065 E22gh1 phosphodiesterase 4D interactin 168.0201 154 282.6456 Q9ULX2 F09ef3 NIMA (never in mitosis gene a) 288.5578 208 283.1715 Q99871 C06ef4 three prime repair exonuclease 2 205.6083 225 283.2504 Q93065 I15cd6 PERB11 family member in MHC 295.7132 457 283.4269 O43837 B12ab7 isocitrate dehydrogenase 3 (NA 348.9961 298 283.6422 Q9H9L3 L06gh7 hypothetical protein FLJ12671 209.5906 279 283.6912 Q13740 A18ab2 activated leucocyte cell adhesio 231.4555 253 283.7582 Q12888 L09cd2 tumor protein p53 binding protei 132.9276 223 283.8572 P78318 J13ab6 immunoglobulin (CD79A) binding 423.8715 512 283.9511 P48436 K24cd1 SRY (sex determining region Y)- 345.2087 197 284.0786 P18065 B19ef1 insulin-like growth factor binding 286.6516 283 284.2331 Q9ULW6 F22cd8 nucleosome assembly protein 1- 223.0694 148 284.717 O95154 N03cd7 aldo-keto reductase family 7; me 299.9079 298 284.8919 O95169 P14ab8 NADH dehydrogenase (ubiquino 374.2624 199 285.0096 Q99982 C24ef4 XIAP associated factor-1 63.10609 116 285.0252 Q99470 F14cd2 stromal cell-derived factor 2 230.3684 316 285.1394 P16104 N19ab5 H2A histone family; member X 234.8351 195 285.2056 Q9UG25 B04ef8 SOCS box-containing WD protei 213.293 398 285.5392 Q13158 C21cd4 Fas (TNFRSF6)-associated via d 263.0157 281 285.9553 Q9NW32 D10gh2 hypothetical protein FLJ10346 235.0532 386 286.3524 O95153 M05cd5 peripheral benzodiazepine recep 155.1824 231 287.1271 Q9BQ73 H06gh7 hypothetical protein FKSG28 212.0736 297 287.201 Q15426 C02ef7 protein tyrosine phosphatase; re 296.9619 441 287.2583 Q92858 L12ab2 atonal homolog 1 (Drosophila) 611.3779 278 287.2641 Q16849 P15ab8 protein tyrosine phosphatase; re 145.9896 55.6 287.3262 P11279 D07ab7 lysosomal-associated membrane 369.9925 310 287.3935 Q96II1 I16gh7 hypothetical protein MGC14961 103.7251 80.7 287.4071 P78504 O20ab2 jagged 1 (Alagille syndrome) 255.0945 347 287.4633 O75937 G06ef3 DnaJ (Hsp40) homolog; subfami 294.9992 264 287.503 O60575 O16ef4 serine protease inhibitor; Kazal 142.2326 152 287.9 Q9NYP7 K05gh5 homolog of yeast long chain poly 299.2029 187 288.1627 O95436 H01cd6 solute carrier family 34 (sodium 238.6021 425 288.3247 O95324 B15ab2 ATP-binding cassette; sub-family 267.704 275 288.4558 Q9UQF6 B08ef3 ribosomal protein L36 519.2003 425 288.5855 P13010 K12ef6 X-ray repair complementing defe 174.6996 256 288.9405 Q9UJZ1 P03cd8 stomatin (EPB72)-like 2 490.6115 272 289.2003 P50281 I18ab7 matrix metalloproteinase 14 (mer 126.7204 196 289.8803 P15927 B08cd1 replication protein A2 (32 kD) 100.0172 194 290.3306 O75496 B02ef1 geminin 466.4376 454 290.7216 Q9P1E3 C23gh4 presenilins associated rhomboid- 232.5496 263 291.2445 P40189 B14ab6 interleukin 6 signal transducer (g 330.8834 315 291.3287 Q9Y259 H03ab4 choline kinase-like 328.1801 375 291.3288 O00633 C12ef5 phosphatase and tensin homolog 199.7323 189 291.6118 Q13432 H13cd5 unc-119 homolog (C. elegans) 127.1818 268 291.793 Q9Y677 E03ef2 COP9 constitutive photomorpho 186.9367 204 291.9539 Q9BW24 D03ef8 KIAA0676 protein 170.3265 240 292.9836 Q9NSD9 B12cd5 phenylalanyl-tRNA synthetase b 226.6641 219 293.111 Q9NWQ0 C16gh3 hypothetical protein FLJ20695 497.4612 656 293.1504 Q9NWT6 C02gh3 hypoxia-inducible factor 1; alpha 521.7793 276 293.7543 Q9UPN3 J12ef7 microtubule-actin crosslinking fa 578.3578 563 294.1533 Q96HW0 A06gh7 zinc finger protein 38 (KOX 25) 126.7599 355 294.3016 Q14257 F18ab8 reticulocalbin 2; EF-hand calciu 237.969 217 295.1469 Q9NRJ5 J05gh4 poly(A) polymerase beta (testis s 379.2857 276 295.7341 P23280 P02ab3 carbonic anhydrase VI 137.6155 102 296.1358 Q14677 I02gh1 KIAA0171 gene product 330.738 204 296.1674 Q9Y394 H17ef2 CGI-86 protein 471.0368 358 296.7589 Q9UKX5 L18cd7 integrin; alpha 11 99.18133 126 297.0397 Q92539 G02gh1 lipin 2 260.7493 235 297.1151 Q9NW01 G10gh3 hypothetical protein FLJ10402 165.6121 135 297.1276 Q9NUW5 N21gh3 hypothetical protein FLJ11099 228.3252 247 297.5163 Q9BYC4 C13gh8 mitochondrial ribosomal protein 478.9122 408 297.754 P02545 F01ab7 lamin A/C 707.7874 294 297.9921 O60585 A17cd6 serine/arginine repetitive matrix 318.399 331 298.2057 P23458 L12ef5 Janus kinase 1 (a protein tyrosin 385.7348 441 298.2124 Q9BY13 O06gh8 hook3 protein 435.0319 471 298.2969 Q9UBC2 C05gh5 epidermal growth factor receptor 171.9695 271 298.6179 O76022 A14cd7 E1B-55 kDa-associated protein 5 256.9682 243 298.7615 P33993 K04ef6 MCM7 minichromosome mainten 239.0601 165 298.875 Q92963 F02cd2 Ric-like: expressed in many tissu 447.2008 499 299.9377 Q9HAF1 P09gh5 hypothetical protein FLJ11730 270.4702 414 300.0397 Q9NZ36 P02gh4 uncharacterized hypothalamus p 505.7323 333 300.1219 Q9BQQ3 C09gh8 golgi phosphoprotein 5 208.3671 343 300.1696 O95214 P09ef3 leptin receptor overlapping trans 292.4076 419 300.357 Q9Y294 A21ef8 DKFZP547E2110 protein 166.5906 243 301.1573 O95810 O01cd4 serum deprivation response (phc 279.903 272 301.2133 P30670 L21ab4 guanine nucleotide binding prote 470.8713 466 301.8899 P51946 O14ef5 cyclin H 180.4218 244 301.9337 Q15290 G18cd1 retinoblastoma binding protein 6 298.4739 346 302.0906 Q9NX11 A03gh3 hypothetical protein FLJ20498 165.3845 190 302.1175 Q9P0S3 A23ef2 hypothetical protein LOC51240 187.2653 229 302.318 P04554 H11ab8 protamine 2 393.1528 362 302.3989 O15243 O05ef4 leptin receptor gene-related prot 329.3033 391 302.5417 O43717 G03cd7 tumor differentially expressed 1 284.4848 364 302.9444 O95876 J10ef1 hypothetical protein LOC51057 172.7128 226 302.9853 Q9H8D5 N17gh5 tumor endothelial marker 6 247.105 190 303.4837 Q9Y3B6 D24ef1 CGI-112 protein 493.6755 288 303.7855 Q9P0S7 E13ef2 hypothetical protein LOC51238 143.0704 139 303.896 O60630 D22ab4 deltex homolog 1 (Drosophila) 310.6617 221 303.9702 O95285 O07gh1 macrophage erythroblast attache 332.2343 413 304.0714 Q08945 G17cd2 structure specific recognition pro 335.05 229 304.6617 O43583 D08cd3 density-regulated protein 203.0088 253 304.7034 O95149 D04cd5 RNA; U transporter 1 186.979 254 304.889 Q9HAS8 N10gh4 elaC homolog 2 (E. coli) 243.3076 331 304.8937 Q9BQ39 A23gh6 nucleolar protein GU2 234.3353 160 305.2734 O15304 C06ef6 CD27-binding (Siva) protein 88.75727 153 305.4708 Q15394 I08gh1 basic leucine-zipper protein BZA 347.7168 384 305.6252 Q9NZA3 N09ef1 CDA14 235.1955 312 305.7623 P26022 P23ab8 pentaxin-related gene; rapidly in 97.61703 61.3 305.8598 Q00536 L24ef5 PCTAIRE protein kinase 1 290.1914 359 306.0473 Q9UMW5 E19ef2 cerebral cell adhesion molecule 52.28353 234 306.6326 O95353 J17cd6 Cdc42 effector protein 3 95.65314 208 306.7186 O95808 B03ef2 arsenate resistance protein ARS 187.799 225 307.4311 Q9BXJ8 O17gh8 transmembrane protein induced I 411.8484 646 308.2116 P36776 A06cd5 protease; serine; 15 390.4608 365 308.5755 Q9BUR9 M19gh6 hypothetical protein MGC4614 250.3191 338 308.7431 Q9Y3R1 F23cd6 Rab acceptor 1 (prenylated) 158.9446 207 308.7948 Q92997 D03ef7 dishevelled; dsh homolog 3 (Dro 240.0941 305 309.2314 O14682 N17cd3 ectodermal-neural cortex (with B 326.0664 189 309.539 Q9Y255 I08cd8 px19-like protein 533.9688 455 309.7497 Q16664 O17ef4 protein \A\** 354.4762 286 310.2736 P31943 O04ab7 heterogeneous nuclear ribonucle 690.0051 250 310.5901 P49848 J09cd2 TAF6 RNA polymerase II; TATA 151.1422 133 310.9274 Q04984 P19ab8 heat shock 10 kD protein 1 (chap 338.1568 327 311.1011 P20719 N08ef4 homeo box A5 271.4135 326 311.2742 Q9H5Y0 D21gh7 hypothetical protein FLJ22795 325.1674 305 311.3753 P19021 G15ab8 peptidylglycine alpha-amidating 219.5791 273 311.913 Q92544 B13gh1 KIAA0255 gene product 270.8313 307 312.0297 Q12907 G07cd7 chromosome 5 open reading frar 313.0938 222 312.5092 Q9BW91 C03gh6 nudix (nucleoside diphosphate li 346.395 314 312.5575 P53365 M23cd8 partner of RAC1 (arfaptin 2) 293.2566 349 312.9335 P35869 O17ab2 aryl hydrocarbon receptor 249.5731 417 313.1153 Q13145 I19cd8 putative transmembrane protein 490.8698 608 313.616 O14747 A18ef6 death-associated protein 6 348.2382 450 313.7398 Q9GZT5 H03gh7 wingless-type MMTV integration 362.0025 327 313.9764 P08174 M19ef1 decay accelerating factor for corr 705.5781 457 314.0939 Q9H689 K01gh4 hypothetical protein RG083M05 241.9641 291 314.1855 Q9P0T7 K05ef2 hypothetical protein LOC51235 266.1575 324 314.3982 Q9H2V7 I12gh8 spinster-like protein 275.9977 394 314.4425 Q9NWT0 D23gh2 hypothetical protein FLJ20625 420.628 488 314.6523 Q9Y6X2 E22cd6 protein inhibitor of activated STA 149.0425 237 315.009 Q9P1P1 F10ef8 clone FLB1727 (LOC51215) 419.9659 330 315.0092 P23919 H04cd7 deoxythymidylate kinase (thymid 123.4582 84.1 315.562 P37140 D09ab8 protein phosphatase 1; catalytic 355.0781 503 315.7751 Q9NW54 B22gh2 homolog of rat nadrin 432.3799 670 315.8314 Q9UMS0 C05ef4 HIRA interacting protein 5 504.0153 382 315.8386 P14207 E23ef1 folate receptor 2 (fetal) 235.5291 154 316.0649 Q9UHC7 L05ef4 makorin; ring finger protein; 1 243.752 243 316.3297 O75844 K23cd6 zinc metalloproteinase (STE24 h 338.221 174 316.3789 P18gh8 LIM homeobox protein 4 87.11814 84.8 316.6454 P16587 P19ab2 ADP-ribosylation factor 3 444.3724 348 317.1873 Q9NVY2 F18gh2 hypothetical protein FLJ10439 420.4716 399 317.2936 Q9Y3I1 J09ef4 F-box only protein 7 368.7457 422 317.6515 Q9H320 P21cd8 variable charge; X chromosome 147.0814 348 318.4769 P49903 J11ef4 selenium donor protein 329.031 446 318.9322 O00506 B05cd6 serine/threonine kinase 25 (STE 273.696 275 319.3179 O00273 F14ab5 DNA fragmentation factor; 45 kD 328.993 401 319.634 Q08170 H11cd2 splicing factor; arginine/seriene-ri 231.1994 193 319.7733 Q9Y3B8 N15ef8 small fragment nuclease 120.8094 282 320.0578 Q9P0N0 E11ef2 mitochondrial ribosomal protein 377.6692 391 320.1382 Q9BRI3 D11gh8 hypothetical protein MGC11303 373.5695 391 320.4318 Q9Y319 D19ef2 CGI-30 protein 107.1253 123 320.4576 Q16514 M17gh1 TAF12 RNA polymerase II; TATA 116.3618 304 320.8611 P13489 D13ef7 ribonuclease/angiogenin inhibito 224.1663 232 321.0895 Q99987 P08ef5 vaccinia related kinase 2 205.9202 194 321.2364 P56181 H21ef1 NADH dehydrogenase (ubiquino 435.0715 319 321.3696 P51148 N18ab8 RAB5C; member RAS oncogene 329.7976 358 321.5906 Q9HD34 E12gh4 CGI-203 protein 257.866 249 322.345 Q9HAN2 F02gh6 purnilio homolog 2 (Drosophila) 291.9641 326 322.4096 P08107 K13ef5 heat shock 70 kD protein 1A 535.4871 382 322.6223 O60499 N18cd3 syntaxin 10 189.7411 304 322.7738 Q9HBL3 M19gh4 N-terminal kinase-like 165.2938 224 323.2472 Q9BSJB D22gh6 KIAA0747 protein 549.1645 575 323.5208 O60838 G09gh7 SAC2 suppressor of actin mutati 216.0571 254 324.4643 Q98TM6 M11gh8 hypothetical protein MGC3195 371.9412 334 324.5103 Q9H4L0 K06gh5 leucine zipper protein FKSG14 47.34403 70.6 324.6661 P50402 I14ab3 emerin (Emery-Dreifuss muscula 321.3743 304 324.6751 Q9NZP7 G05ef3 calcium binding protein Cab45 p 336.1107 239 324.6956 P49116 G22cd2 nuclear receptor subfamily 2; gro 295.9342 224 325.1253 P11234 D14ab8 v-ral sirrian leukemia viral oncog 565.699 444 325.5924 P15408 D21ab5 FOS-like antigen 2 265.6989 437 325.8448 Q9P1Q8 N05cd8 RAB3A interacting protein (rabin 357.8493 253 326.2784 P39060 P16ef6 collagen; type XVIII; alpha 1 151.6584 212 326.8288 Q9Y2N3 N05gh1 KIAA0618 gene product 378.8717 252 326.8347 P02749 M22ab2 apolipoprotein H (beta-2-glycopn 408.7454 226 327.1228 Q9P189 L20gh3 hypothetical protein PRO1855 392.3328 358 327.1908 O43822 B19ab4 chromosome 21 open reading fr 249.9987 297 327.8679 Q9UNZ2 N15ef2 likely ortholog of rat p47 413.5167 519 327.9429 Q9Y4G5 B22cd8 dynein; cytoplasmic; heavy poly 376.6624 426 327.9518 Q13310 C13cd4 poly(A) binding protein; cytoplas 316.8746 338 328.1257 P45974 O14cd3 ubiquitin specific protease 5 (iso 268.1073 316 328.8257 P55317 A04ab7 hepatocyte nuclear factor 3; alph 273.7527 306 328.8562 O43364 H06cd8 homeo box A2 511.053 468 329.1292 P55345 H15ab6 HMT1 hnRNP methyltransferase 364.8758 307 329.5023 P48230 O22cd2 transmembrane 4 superfamily m 565.1635 417 330.825 Q9BUY3 C21gh5 sorting nexin 6 166.5144 297 330.8949 O00115 B01ef6 deoxyribonuclease II; lysosomal 275.2503 372 331.0554 O43318 M11cd2 mitogen-activated protein kinase 186.7739 247 331.1308 O95572 B08gh1 mitofusin 2 252.7846 277 331.4516 P35080 K12ab8 profilin 2 111.4363 85.9 332.2299 Q9NW29 E24gh3 hypothetical protein FLJ10350 219.5611 173 332.8499 Q9NZE9 O07ef2 BRAF35/HDAC2 complex (80 kD 219.3916 348 332.8813 Q9BYV2 C E05gh8 ring finger protein 30 500.2246 338 333.9675 Q9UJX4 F02ef2 anaphase promoting complex sul 237.1218 269 334.5884 O00302 B19cd6 calcium homeostasis endoplasm 327.1489 382 334.7371 Q92886 K23cd1 neurogenin 1 290.2357 283 335.1054 O14929 P07cd3 histone acetyltransferase 1 344.9153 130 335.4301 Q9NVK7 M18gh3 chromosome 19 open reading fre 281.2043 287 335.4383 Q9UBN0 P09ef4 proline rich 3 309.9093 344 335.4526 O43611 E14cd3 cytoplasmic linker 2 180.9108 220 336.1459 O94777 G23cd4 dolichyl-phosphate mannosyltran 294.1356 244 336.7183 Q14669 K05gh1 thyroid hormone receptor interac 486.9829 397 337.0199 Q9NUR0 B20gh3 hypothetical protein FLJ11196 63.09205 107 337.0769 Q16822 L08ab8 phosphoenolpyruvate carboxykin 262.4601 156 337.1655 Q9Y640 A14cd8 stromal cell derived factor recept 215.2348 220 337.2906 P48595 C01cd1 serine (or cysteine) proteinase in 62.04001 410 337.3872 P26639 M15cd2 threonyl-tRNA synthetase 355.1309 422 337.8401 P29597 O03cd3 tyrosine kinase 2 209.3427 258 338.1471 O60671 B02ab8 RAD1 homolog (S. pombe) 188.2716 104 339.1461 Q9NW97 P17gh2 hypothetical protein FLJ10199 262.3124 536 339.3086 Q9P027 O23ef8 HSPC133 protein 616.0461 363 339.3102 O95772 E20gh8 hypothetical protein MGC3251 195.9084 227 339.3844 Q9NR28 N13gh4 second mitochondria-derived act 271.4457 543 339.8107 P11413 F15ab3 glucose-6-phosphate dehydroge 258.0938 135 340.0217 Q99567 A04ab8 nucleoporin 88 kD 464.4826 320 340.5878 Q9BZR9 F22gh7 ring finger protein 27 206.7918 398 340.7239 O43632 L22cd6 gamma-tubulin complex protein 2 328.0052 322 341.4805 Q9Y305 I05cd8 Mitochondrial Acyl-CoA Thioeste 447.9229 475 341.5085 P17096 L14ef6 high-mobility group (nonhistone 393.4158 266 341.5301 P28677 E10cd3 visinin-like 1 235.283 241 341.6123 Q9UBX5 K04cd6 fibulin 5 79.52593 108 341.7638 Q9Y304 E12ef2 ovarian cancer overexpressed 1 326.0044 238 341.8947 O15379 L16ef6 histone deacetylase 3 198.0005 380 342.3529 Q02790 H16ab5 FK506 binding protein 4 (59 kD) 323.5993 240 343.4254 Q9H240 K12ef5 Notch homolog 2 (Drosophila) 270.5904 566 343.4339 O76095 P22cd6 jumping translocation breakpoint 252.8696 227 343.482 Q9Y5Q8 P07cd7 general transcription factor IIIC; 545.6403 324 343.9958 Q9NNW5 H06ef8 WD repeat domain 6 254.1607 369 344.0253 P01121 C09ef6 ras homolog gene family; memb 241.7544 304 344.0732 Q9H0V7 K18gh8 hypothetical protein DKFZp564O 568.248 304 344.2985 O60664 P02cd5 cargo selection protein (mannos 520.0919 232 344.5523 P56554 O15cd3 ubiquitin-conjugating enzyme E2 374.4383 417 345.0269 O00330 O06cd3 Pyruvate dehydrogenase comple 345.9372 430 345.2213 O60784 N17cd5 target of myb1 (chicken) 364.3098 317 345.2431 Q9NQZ0 H03ef4 CMP-N-acetylneuraminic acid sy 788.5176 339 345.3498 P52790 A04ab5 hexokinase 3 (white cell) 260.6034 430 345.4621 P52815 B10cd1 mitochondrial ribosomal protein 234.3191 277 345.7776 O14983 O10ef1 ATPase; Ca++ transporting; card 167.4068 223 346.1734 P04259 D01ab7 keratin 6B 534.1837 405 347.6543 P16455 M04ef6 O-6-methylguanine-DNA methylt 299.0887 307 348.0545 Q9Y5L9 N04cd6 Snf2-related CBP activator protei 285.2875 187 348.0925 P41214 A16gh1 ligatin 237.0742 307 348.5538 Q9H6U4 P13gh5 hypothetical protein FLJ21865 419.2747 175 348.8375 Q15393 L10ef7 splicing factor 3b; subunit 3; 130 242.1115 239 349.6571 P55055 C04gh1 nuclear receptor subfamily 1; gro 325.6291 368 349.8393 P51805 M03ef4 SEX gene 303.0664 383 350.6414 O75815 G23ab3 breast cancer anti-estrogen resis 249.1903 293 350.9571 Q9Y2Y9 F19ef2 Kruppel-like factor 13 241.1753 366 351.0501 Q99633 D04cd3 pre-mRNA processing factor 1 405.046 348 351.3478 P05155 C08ab3 serine (or cysteine) proteinase in 303.3386 334 351.5074 Q9UN50 O16cd7 EAP30 subunit of ELL complex 321.9045 326 351.5535 Q14011 E11ab4 cold inducible RNA binding prote 292.5107 412 351.6685 O75807 M02ef3 protein phosphatase 1; regulator 371.7509 652 352.5048 Q14457 K19ab3 beclin 1 (coiled-coil; myosin-like 368.4142 678 352.9542 Q02818 J06ef6 nucleobindin 1 330.8747 213 353.1168 O15235 L10gh1 mitochondrial ribosomal protein 355.1234 467 353.2438 Q9Y3E0 A02ef2 CGI-141 protein 152.8668 320 353.6986 Q9NQZ5 H19gh4 START domain containing 7 277.2941 280 353.7264 Q9UHW4 D24ef8 protein × 0001 266.9848 291 353.7644 P82914 P04gh7 mitochondrial ribosomal protein 444.1517 417 354.4965 P25787 L11ef7 proteasome (prosome; macropal 432.9379 526 355.1116 P26447 D02cd1 S100 calcium binding protein A4 198.7401 273 355.1396 Q9Y605 P02gh8 T-cell activation protein 411.1148 356 355.1531 Q14776 K14cd4 leucine-zipper-like transcriptiona 202.0365 273 355.4522 P30837 C02ab2 aldehyde dehydrogenase 1 famil 631.0407 451 355.7998 P09668 L03ef7 cathepsin H 460.8488 564 356.7735 Q02313 J02gh6 Krueppel-related zinc finger prot 402.289 391 356.9162 Q13148 H11cd7 TAR DNA binding protein 322.5816 353 357.1404 Q16645 K24ab5 FK506 binding protein 1B (12.6 216.7704 486 357.2698 N02gh8 protein phosphatase 1; regulator 77.52993 71.1 357.2714 P57739 F18gh1 claudin 2 188.162 238 357.443 O60568 F13cd4 procollagen-lysine; 2-oxoglutarat 332.5306 269 357.5594 Q9HAU4 N11gh5 E3 ubiquitin ligase SMURF2 425.5948 665 357.6911 P49914 J01cd6 5; 10-methenyltetrahydrofolate sy 340.2344 238 358.0826 O60510 E11cd8 atrophin-1 interacting protein 1; 171.9425 265 358.342 Q9BX68 L15gh8 histidine triad nucleotide binding 207.0703 360 358.5328 P29084 B02ab5 general transcription factor IIE; p 261.3572 225 358.821 P09526 C05ef6 RAP1B; member of RAS oncoge 320.4156 355 359.0861 O15471 P01ef4 leukocyte immunoglobulin-like re 219.8277 260 359.2909 Q9UEE9 K03ab3 craniofacial development protein 124.0304 245 359.5047 Q15011 L03ef3 homocysteine-inducible; endopla 352.4459 183 359.7095 Q9BWG8 A13gh6 hypothetical protein MGC2491 170.1162 203 360.534 Q9Y397 A04ef2 zinc finger; DHHC domain contai 431.1743 495 360.6182 Q14596 H17ab7 membrane component; chromos 303.2476 402 361.5265 P23497 C13cd2 nuclear antigen Sp100 331.8296 491 361.9825 Q16633 A24cd1 POU domain; class 2; associatin 103.1231 99.3 362.0007 Q99961 J12cd1 SH3-domain GRB2-like 1 231.086 247 362.8536 Q07021 N20ab3 complement component 1; q sub 471.8742 202 363.3385 Q16513 E04cd1 protein kinase C-like 2 546.0111 561 364.4852 Q9H070 H10cd8 adaptor-related protein complex: 353.2901 278 364.7541 Q13227 A16ab5 G protein pathway suppressor 2 557.5311 352 364.8449 P20339 M03ef5 RAB5A; member RAS oncogene 404.6579 664 365.7139 Q9NXX4 G15gh2 hypothetical protein FLJ20005 155.2731 246 365.9622 Q92900 N17cd1 regulator of nonsense transcripts 328.2926 316 366.2931 Q9H2K4 I05gh3 chromosome 11 open reading fr 198.6548 155 366.4866 O14917 E17ef4 protocadherin 17 250.3859 311 366.6879 Q9NZ88 J06gh3 chromosome 6 open reading frar 199.6701 362 367.2681 Q9BYC8 C15gh8 mitochondrial ribosomal protein 257.9414 429 367.9727 Q15311 C21cd7 ralA binding protein 1 295.4648 411 368.6028 Q9NWE9 E02gh3 hypothetical protein FLJ10074 455.3747 383 369.4489 O95571 G22ef3 protein expressed in thyroid 398.0124 507 369.925 P36941 A09ab7 lymphotoxin beta receptor (TNFF 403.0565 454 370.0343 P49790 F11cd5 nucleoporin 153 kD 264.6175 316 370.2793 Q99607 C06ab4 E74-like factor 4 (ets domain trar 267.135 268 371.3515 Q9UIV1 H05cd8 CCR4-NOT transcription comple; 201.0959 465 371.6771 Q9Y3E4 O13ef2 CGI-146 protein 107.5317 262 371.8333 P19367 D17ab3 hexokinase 1 512.0647 215 371.9817 Q14250 J15cd5 enigma (LIM domain protein) 229.1944 218 371.9927 Q9UL33 B20ef2 unknown 343.1533 636 372.4427 Q15019 H03ef5 neural precursor cell expressed; 489.0601 274 372.9279 Q13084 H05cd6 melanoma-associated antigen re 421.8259 278 373.0512 Q9UMR2 O18cd7 DEAD/H (Asp-Glu-Ala-Asp/His) 383.654 423 373.0622 P55855 H06cd2 SMT3 suppressor of mif two 3 ho 454.9011 444 373.596 Q13155 G20cd4 JTV1 gene 322.6641 409 373.7416 P78371 H11cd6 chaperonin containing TCP1; su 480.5464 430 374.014 P08173 P17ab3 cholinergic receptor; muscarinic 444.2461 514 374.4117 O60478 E02cd2 transmembrane 7 superfamily m 274.7639 438 374.61 O60429 D16gh4 hypothetical protein FLJ12886 142.8322 257 375.0573 O75935 O04cd7 dynactin 3 (p22) 408.9696 432 375.1224 Q13147 J05ab2 abl-interactor 2 299.098 249 375.379 Q9NPH4 E14gh3 LUC7-like (S. cerevisiae) 207.38 302 376.3768 Q9UJ96 C13cd8 potassium voltage-gated channe 582.717 448 376.4373 P17081 C13ef6 likely ortholog of mouse TC10-al 293.1604 417 376.4996 P11166 J05ef5 solute carrier family 2 (facilitated 351.7333 393 376.564 Q14820 D12ef6 splicing factor 1 382.846 408 376.7779 Q92935 I06ab5 exostoses (multiple)-like 1 659.9005 276 376.8548 P31749 E20ef6 v-akt murine thymoma viral onco 385.4669 303 376.9169 Q13454 L05cd7 Putative prostate cancer tumor s 326.9146 363 377.0852 P35520 C24ab3 cystathionine-beta-synthase 70.85109 68.1 377.1148 P53602 M01ab7 mevalonate (diphospho) decarbc 682.0309 178 378.114 Q9H7G3 C04gh6 mitochondrial ribosomal protein 333.6677 207 378.1396 Q13123 C06ab7 IK cytokine; down-regulator of HI 257.7332 439 378.1806 O14744 G14cd6 SKB1 homolog (S. pombe) 348.0026 410 378.4165 Q9Y566 D16ef8 SH3 and multiple ankyrin repeat 209.2687 281 379.5197 Q9BUJ9 A03gh7 Mov10; Moloney leukemia virus 385.0517 472 380.308 P51790 I02ab5 chloride channel 3 330.2251 237 380.3105 O14547 J09cd6 PRP8 pre-mRNA processing fact 239.0005 256 380.5886 Q99753 A05cd7 cisplatin resistance associated 257.1873 397 380.7894 Q9NQC8 H15gh4 hypothetical protein LOC58912 185.2607 276 381.0416 O43919 M01ef6 linker for activation of T cells 206.6586 105 381.2059 P78345 F15cd6 ribonuclease P (38 kD) 321.791 530 381.5687 P54257 A03ef5 huntingtin-associated protein 1 ( 450.2874 322 382.6029 Q9Y3F4 G18cd7 unr-interacting protein 390.9437 335 382.6142 P29536 F14cd7 leiomodin 1 (smooth muscle) 343.3731 209 382.9438 O75925 K03cd4 protein inhibitor of activated STA 423.9992 606 383.7943 Q9UMX5 J23ef4 secreted protein of unknown fun 344.8668 306 384.5676 Q9UMZ9 N02cd7 interleukin enhancer binding fact 348.7866 278 384.7729 Q92905 P03ef6 COP9 constitutive photomorphog 257.5597 392 386.1452 Q9NSD7 L20ef1 G-protein coupled receptor SALF 734.6282 277 386.7193 Q9P2W3 G01ef3 guanine nucleotide binding prote 70.71144 81.4 386.7442 Q9BVI7 N14gh5 mitochondrial ribosomal protein 367.7177 520 386.9198 Q9Y4L1 B23cd6 oxygen regulated protein (150 kD 413.0575 372 387.5372 Q02363 F18ab7 inhibitor of DNA binding 2; domir 484.7132 359 388.2552 Q9Y5J8 E06cd8 translocase of inner mitochondri 440.2763 542 388.4554 E22ef1 G protein-coupled receptor 26 499.1316 450 389.582 Q99501 N11cd6 growth arrest-specific 2 like 1 359.8065 540 389.6398 Q00613 M17ef5 heat shock transcription factor 1 363.3847 375 389.8695 Q9H5Z1 H16gh4 DEAD/H (Asp-Glu-Ala-Asp/His) t 136.5899 124 389.9835 P09661 P24cd1 small nuclear ribonucleoprotein 441.1409 115 390.2085 P54709 P05ef5 ATPase; Na+/K+ transporting; b 425.6647 432 391.8135 P13164 M06ef5 interferon induced transmembra 45.13817 256 392.1204 Q9Y6E2 A23ef8 HSPC028 protein 329.8857 363 392.2431 Q9NVG2 B13gh3 vacuolar protein sorting 35 (yeas 359.0233 557 392.2574 P27448 E10ef5 MAP/microtubule affinity-regulati 397.7845 369 392.3918 O15438 P18cd3 ATP-binding cassette; sub-family 618.0409 488 392.8159 Q9UL48 I04ef2 CK2 interacting protein 1; HQ002 176.5553 215 393.4111 O94763 A11cd4 RPB5-mediating protein 333.6215 533 393.9448 Q13190 I19cd2 syntaxin 5A 179.6148 235 393.985 Q13122 D21ef3 EBNA-2 co-activator (100 kD) 381.3069 375 394.5999 O75312 L01cd4 zinc finger protein 259 348.7542 422 394.8016 P37837 D20cd2 transaldolase 1 399.2717 326 395.693 O75762 G19cd6 ankyrin-like with transmembrane 222.8517 364 395.7427 Q99969 K19ef3 retinoic acid receptor responder 283.5705 257 396.0287 Q9UNP2 H15cd2 solute carrier family 1 (neutral an 149.1019 138 396.5014 P56524 C23cd6 histone deacetylase 4 328.6037 303 397.1317 Q9H644 C19gh6 hypothetical protein MGC5585 140.9811 228 397.2624 Q13627 O19ab4 dual-specificity tyrosine-(Y)-phos 498.484 327 397.3922 Q03405 O01ef5 plasminogen activator; urokinase 500.1391 396 398.2456 Q9NPQ8 L18gh4 likely ortholog of mouse synemb 372.8251 443 398.4083 Q15375 A10ab5 EphA7 243.0574 290 398.5414 P05114 G04ab7 high-mobility group (nonhistone 196.8334 278 398.7327 Q9UKU4 C13ef2 retinal short-chain dehydrogenas 370.8225 497 399.4413 P08195 E21ab7 solute carrier family 3 (activators 442.5453 345 399.5678 Q15545 J11cd2 TAF7 RNA polymerase II; TATA 400.689 526 401.1308 D24gh8 hypothetical protein FLJ14511 246.3293 225 401.3816 Q05397 L20ef5 PTK2 protein tyrosine kinase 2 389.8718 440 401.4713 Q9Y6G1 C21ef8 PTD011 protein 434.6906 483 401.5119 P41212 O23ef5 ets variant gene 6 (TEL oncogen 315.7331 502 401.8428 O14737 G05cd5 programmed cell death 5 498.729 430 402.3091 Q9UHB9 A10ef3 signal recognition particle 68 kD 212.5357 247 402.3276 Q96D21 C20ef8 RASD family; member 2 395.909 486 402.4304 Q9Y4I1 J05ef1 myosin VA (heavy polypeptide 1 371.5954 353 402.453 Q9Y5L4 L14ef7 translocase of inner mitochondri 291.7019 369 404.0738 O75439 N22cd4 peptidase (mitochondiral proces 512.9004 184 404.5715 P55010 K22ab4 eukaryotic translation initiation fa 427.4989 296 405.4996 Q9BY44 G10gh8 CDA02 protein 453.6064 401 405.956 Q13164 B21ef5 mitogen-activated protein kinase 209.1026 256 406.234 P53667 P08ab6 LIM domain kinase 1 359.4655 392 406.5183 Q9UNH6 F05ef2 sorting nexin 7 479.6898 396 406.7812 O00258 K17cd4 tryptophan rich basic protein 339.3172 500 407.1504 Q9Y3I0 I12ef3 hypothetical protein 458.2693 546 407.2408 Q9Y368 D13cd8 parvin; beta 114.232 159 407.3882 P14866 H13ab6 heterogeneous nuclear ribonucle 442.5489 274 407.4025 Q13885 K01cd3 tubulin; beta polypeptide 441.2669 413 407.8683 O43765 J06cd1 small glutamine-rich tetratricope 378.9705 438 408.6453 O14632 B12ef4 homeodomain interacting protein 394.449 535 408.8773 P31939 L10ab2 5-aminoimidazole-4-carboxamid 501.3028 386 409.3069 P28331 P18ab8 NADH dehydrogenase (ubiquino 490.4347 417 409.3283 P41970 P05ef6 ELK3; ETS-domain protein (SRF 205.9453 359 410.8037 Q92973 J22ab6 karyopherin (importin) beta 2 393.6551 234 410.9425 P36507 J10ef5 mitogen-activated protein kinase 395.22 437 411.4052 Q16512 F21ab8 protein kinase C-like 1 456.2727 486 411.8245 O43447 M08cd6 peptidyl prolyl isomerase H (cyc 179.441 222 411.9165 P30040 M13ef3 chromosome 12 open reading fr 346.6792 296 412.2064 O95399 C19cd7 urotensin 2 452.0721 366 413.1451 M01ab3 UDP-Gal:betaGal beta 1; 3-galac 499.9529 290 413.3454 Q12792 N11ab8 protein tyrosine kinase 9 476.3952 364 413.4208 Q14318 J02cd7 FK506 binding protein 8 (38 kD) 461.2322 432 413.4238 O75955 N10cd5 fiotillin 1 304.6674 310 415.4364 Q9BVY8 B09gh7 hypothetical protein MGC5499 490.2382 417 416.02 Q16288 O19ef5 neurotrophic tyrosine kinase; rec 126.7467 188 416.4128 O75380 J20ab8 NADH dehydrogenase (ubiquino 449.5778 413 416.4836 Q9BY51 B15gh8 hypothetical protein GL009 429.1998 354 417.3575 Q9BVK3 E19gh6 hypothetical protein MGC2463 462.5828 387 417.7046 Q9P0N3 A24ef2 hypothetical protein FLJ10597 137.7487 289 417.999 P24534 D03ab4 eukaryotic translation elongation 347.2405 328 418.0152 P49336 C01ab4 cyclin-dependent kinase 8 426.3751 281 418.121 P34130 P16cd2 neurotrophin 5 (neurotrophin 4/5 327.4146 223 418.6011 O75425 P06gh5 hypothetical protein AF053356_ 340.4357 339 419.3637 Q15293 F16ab8 reticulocalbin 1; EF-hand calciu 241.6383 250 420.5597 O95376 D08ab2 ariadne homolog 2 (Drosophila) 254.1122 322 420.8229 O75489 J16ab8 NADH dehydrogenase (ubiquino 375.7034 327 422.3772 P28482 B15ef5 mitogen-activated protein kinase 493.835 452 422.4625 P20823 B09cd1 transcription factor 1; hepatic; LF 322.4782 527 423.4405 O15250 I04cd4 X-prolyl aminopeptidase (amino 524.8188 542 423.7387 P55769 P22ab8 NHP2 non-histone chormosome 137.3557 479 424.0031 O94817 N21ab2 APG12 autophagy 12-like (S. ce 631.6055 402 424.3577 O75352 K08cd5 mannose-P-dolichol utilization d 272.444 523 424.8266 Q16585 I16cd1 sarcoglycan; beta (43 kD dystrop 256.2113 293 425.1172 Q9H7X7 B16gh5 hypothetical protein FLJ14117 261.9578 463 425.3725 O15173 I16cd6 progesterone receptor membrane 295.0481 244 425.8728 Q9GZX9 A16gh4 twisted gastrulation 84.61732 147 426.1124 Q16594 M09cd2 TAF9 RNA polymerase II; TATA 171.3507 520 426.7606 O00479 O17gh1 high-mobility group (nonhistone 265.695 354 426.7642 P54760 C22ab5 EphB4 528.7066 413 427.0543 P25490 F06ef6 YY1 transcription factor 481.2844 530 427.184 Q9UJY0 B07ef3 putative nucleotide binding prote 505.9493 431 427.3544 Q09666 A22ef1 AHNAK nucleoprotein (desmoyol 392.0671 399 427.3828 O15305 P22ab7 phosphomannomutase 2 325.0777 480 428.3778 O60492 M09ab4 7-dehydrocholestrol reductase 388.5228 213 428.5923 Q9UND3 G11cd6 nuclear pore complex interacting 280.8175 312 428.5952 Q9HB15 M15gh5 potassium channel: subfamily K: 473.5589 408 428.9306 Q9Y3B4 H23ef2 CGI-110 protein 290.9669 331 429.1497 Q14107 F05ef5 D123 gene product 387.0465 405 429.9331 P52435 A22cd1 polymerase (RNA) II (DNA direct 527.0446 461 429.9488 Q9Y262 L11ef2 eukaryotic translation initiation fa 591.5767 311 430.6788 P10163 L20cd2 proline-rich protein BstNI subfam 521.4154 251 431.1299 P38378 F01cd8 protein transport protein SEC61 635.5838 369 431.9958 P48735 B06ab6 isocitrate dehydrogenase 2 (NA 600.2178 338 432.1616 Q9NPF5 F02gh4 DNA methyltransferase 1-associ 451.5343 382 432.3473 O14616 K22cd4 zinc finger protein-like 1 194.5871 348 432.4885 Q00839 A12ab7 heterogeneous nuclear ribonucle 416.5145 410 432.5188 O95563 J15ef8 DKFZP564B167 protein 390.848 389 432.8082 Q92974 I03cd6 rho/rac guanine nucleotide exch 142.3392 124 433.2386 Q9UEE5 M07cd5 serine/threonine kinase 17a (apc 397.8599 472 433.4221 Q9NX81 O19gh3 BTB (POZ) domain containing 2 175.3887 206 433.4811 Q9NXF9 O01gh3 O-linked mannose beta1; 2-N-ac 477.6375 353 434.2927 P98171 F13ef1 Rho GTPase activating protein 4 368.9887 231 435.3585 P56192 I14ab7 methionine-tRNA synthetase 263.0076 295 435.894 O95411 K09cd5 TGFB1-Induced anti-apoptotic fa 233.3926 310 436.2684 P09132 E23cd2 signal recognition particle 19 kD 227.8193 595 436.5994 Q92537 O24gh1 KIAA0247 gene product 291.1054 232 437.1141 P49761 G03ab4 CDC-like kinase 3 458.9286 562 437.5601 Q9HDC4 O19gh4 junctophilin 3 346.7829 388 439.282 P98160 A13ef7 heparan sulfate proteoglycan 2 ( 505.6962 372 439.9544 Q9NQV6 O22gh4 PR domain containing 10 369.157 514 440.5347 Q9NRX6 J09gh4 protein × 013 324.5306 345 440.8995 O76084 A13cd4 catenin (cadherin-associated pro 471.1305 211 441.7617 P23197 E19cd7 chromobox homolog 1 (HP1 beta 480.8183 362 441.9595 Q99439 E10ab6 calponin 2 429.1961 304 442.4148 O14656 O04ef6 dystonia 1: torsion (autosomal d 415.3893 533 442.9429 Q9NPJ3 P04gh4 uncharacterized hypothalamus p 411.0811 430 443.2575 P41226 B10ef7 ubiquitin-activating enzyme E1- 298.6597 342 443.334 Q9Y478 C24cd1 protein kinase; AMP-activated; b 306.0158 165 443.5049 P06cd8 nodal homolog (mouse) 349.4202 252 443.7188 Q12904 O06ef7 small inducible cytokine subfamil 374.6683 459 445.5171 P20264 C02cd1 POU domain; class 3; transcription 458.6994 302 447.8929 Q15428 B11cd4 splicing factor 3a; subunit 2; 66 kD 284.0454 334 448.6652 P49771 G06ef6 fms-related tyrosine kinase 3 liga 449.6827 417 452.1329 P49005 A18cd1 polymerase (DNA directed); delt 363.5225 232 452.6832 Q99879 M14gh6 H2B histone family; member E 325.9523 483 452.8012 P49821 G20cd1 NADH dehydrogenase (ubiquino 511.5488 392 454.6223 P10644 H22ef5 protein kinase; cAMP-dependent 420.8225 518 454.8256 Q9Y5J4 L17gh6 pyrroline 5-carboxylate reductase 145.6987 303 455.1667 P31040 K02cd2 succinate dehydrogenase compl 671.3369 351 456.2212 Q9UHA2 F04ef8 synovial sarcoma translocation g 438.6951 480 456.469 Q9UBF6 C02ef3 ring finger protein 7 315.6541 400 456.9368 Q9Y5S2 C21cd6 CDC42 binding protein kinase b 386.9683 447 456.9709 P20809 H07ef7 interleukin 11 399.048 140 458.1544 Q13526 F21ef5 protein (peptidyl-prolyl cis/trans 333.4194 460 458.2237 Q9NWQ9 H01gh2 hypothetical protein FLJ20671 430.7122 577 458.2293 Q9Y6J0 E05cd8 calcineurin binding protein 1 474.3964 117 458.7489 Q9Y4Z6 B13cd7 vacuolar protein sorting 45A (ye 115.1679 276 458.8586 Q01433 G02ab2 adenosine monophosphate dean 352.5251 390 459.2935 O43181 M07ab8 NADH dehydrogenase (ubiquino 417.4586 432 460.2425 Q9NWT5 D15gh2 hypothetical protein FLJ20618 354.3599 523 460.3326 O75431 P19cd6 metaxin 2 282.4791 443 460.352 P09543 A18gh7 2′;3′-cyclic nucleotide 3′ phospho 258.2862 510 462.033 Q9BTE1 B05gh8 dynactin 4 562.6142 460 462.4054 P16152 H14ab5 carbonyl reductase 1 234.3184 240 463.6916 O15121 D06cd3 degenerative spermatocyte homo 264.7024 270 464.4612 O60909 E09ab3 UDP-Gal: betaGlcNAc beta 1; 4- 365.8881 379 464.9697 O75223 C11gh6 hypothetical protein MGC3077 493.9011 276 465.7709 Q9BQA1 K03gh6 MEP50 protein 379.1943 303 466.1997 O43427 F20cd4 fibroblast growth factor (acidic) 323.6471 325 466.8724 Q9BWG6 A15gh6 hypothetical protein MGC3180 309.3486 596 468.0924 Q9Y6R2 M04cd6 chromosome 4 open reading frar 337.7358 352 469.9502 Q9HBK7 M07gh4 NPD007 protein 367.4893 489 471.1924 P52758 E04ef7 translational inhibitor protein p14 324.9333 318 471.2741 P47897 E19cd1 glutaminyl-tRNA synthetase 400.1718 364 472.5359 Q9BWQ6 P20gh5 hypothetical protein MGC3262 288.8083 483 473.0084 P35325 H22cd2 small proline-rich protein 2B 390.5307 584 474.2762 Q9HA68 O23gh5 hypothetical protein FLJ12154 556.3876 383 474.593 P49366 P16ab5 deoxyhypusine synthase 458.6886 481 477.1999 Q9UKZ7 J18ef1 colon carcinoma related protein 505.0182 450 478.4787 P01730 K15ef5 CD4 antigen (p55) 516.4046 432 478.8033 P20674 L06cd4 cytochrome c oxidase subunit Va 512.4055 372 480.2708 Q12828 H02ef6 far upstream element (FUSE) bin 462.592 312 480.5079 Q9Y6A4 J18ef3 similar to mouse Git3 or D. malar 359.9248 485 480.8661 O60888 B09ef2 divalent cation tolerant protein C 298.6981 304 481.136 O75716 F08cd3 serine/threonine kinase 16 364.1875 379 481.1652 P30711 E18ef7 glutathione S-transferase theta 1 327.8121 533 481.9461 Q15008 L03gh1 KIAAO107 gene product 475.6485 506 482.3327 P17174 N07ab4 glutamic-oxaloacetic transamina 412.5293 224 484.4384 P13798 K16ab2 N-acylaminoacyl-peptide hydrola 365.1218 351 484.44 Q9P2R8 E15ef4 Misshapen/NIK-related kinase 469.5725 511 484.515 Q9UNT1 E20cd7 RAB; member of RAS oncogene 268.916 347 484.9919 O75607 L11cd7 nucleophosmin/nucleoplasmin; 3 350.2387 272 485.5671 O94925 B20gh1 glutaminase 410.4357 471 486.8946 O95390 A06ab3 growth differentiation factor 11 264.606 324 489.3912 O75956 K13cd6 tumor suppressor deleted in oral 524.962 482 489.6212 O95573 I23ab5 fatty-acid-Coenzyme A ligase; lo 354.1387 174 489.6455 Q9BXH1 N23gh6 Bcl-2 binding component 3 493.3887 433 492.1083 P13662 L20cd5 nuclear transport factor 2 392.576 479 492.4942 Q92793 H05ab5 CREB binding protein (Rubinstel 468.559 474 494.3525 Q9P0H6 K23ef4 AD-012 protein 406.4789 469 495.1858 Q9P0R3 C05ef3 hypothetical protein HSPC213 339.0916 509 495.2656 O75094 E11gh1 slit homolog 3 (Drosophila) 345.9855 439 496.3812 Q9P011 P10ef2 non-canonical ubquitin conjugati 460.4398 538 497.256 Q92504 M12cd4 HLA class II region expressed g 251.7256 339 497.6138 O95190 L12cd8 omithine decarboxylase antizym 421.0592 441 497.6839 Q9Y230 N12cd6 RuvB-like 2 (E. coli) 342.0841 300 497.7767 Q9BSG0 M16gh8 chromosome 2 open reading frar 324.5321 458 497.8462 Q9Y366 I17ef2 chromosome 20 open reading fra 278.1968 453 498.3057 Q14094 O24ef5 cyclin I 407.6242 354 499.6223 P43403 H04ef5 zeta-chain (TCR) associated pro 396.0583 396 500.6282 P52803 H23ef7 ephrin-A5 357.5339 316 501.0718 O95402 E18cd5 cofactor required for Sp1 transcri 106.0683 58.7 501.9814 O00233 L23ab8 proteasome (prosome; macropali 581.8818 399 502.2082 Q9H1K6 O18gh7 mesoderm development candidar 432.735 560 502.7516 Q9BXL6 K15gh6 caspase recruitment domain prot 425.1251 523 502.8514 Q9H173 H03gh5 endoplasmic reticulum chaperon 456.5646 449 503.5156 Q9NV83 H03gh3 hypothetical protein FLJ10876 423.9423 497 504.9702 P11926 A12ab8 omithine decarboxylase 1 591.3922 362 505.3016 Q04743 D23ef1 empty spiracles homolog 2 (Dros 531.3866 311 505.7367 Q9BVK2 G11gh6 hypothetical protein MGC2840 si 388.8682 383 505.9804 O43251 I16ef3 RNA binding motif protein 9 346.6445 530 507.0674 Q99829 L13cd4 copine I 355.3783 268 508.4915 O95777 B10ef2 U6 snRNA-associated Sm-like pr 391.981 311 508.8683 Q9UN53 C19ef2 calcium binding protein Cab45 pr 327.721 407 509.3316 P24310 F03ab4 cytochrome c oxidase subunit VII 184.0695 288 509.4504 Q9H929 N09gh5 hypothetical protein FLJ13055 387.341 500 510.1197 P10768 K19ef1 esterase D/formylglutathione hyd 596.3068 102 510.5002 O95287 D17cd5 golgi autoantigen; golgin subfam 346.1135 560 510.6433 Q01105 H18cd1 SET translocation (myeloid leuke 328.6513 403 511.1477 Q9UK45 B08ef2 U6 snRNA-associated Sm-like pr 388.4486 551 511.9386 P35611 I17ab2 adducin 1 (alpha) 435.0349 519 512.6447 O14681 K22cd5 etoposide-induced mRNA 451.5599 324 516.5292 P80303 A05cd1 nucleobindin 2 296.1418 236 516.7037 Q9NWC0 N19gh2 F-box only protein 4 434.5394 477 517.7728 P00367 B06ab5 glutamate dehydrogenase 1 360.6 303 518.2525 O00469 I09ab8 procollagen-lysine; 2-oxoglutarat 735.8327 238 518.6446 Q9UI04 M18ef4 mitochondrial ribosomal protein I 364.1383 336 520.377 P20338 N08ab8 RAB4A; member RAS oncogene 487.9427 457 520.7608 Q9HCU8 I19gh4 polymerase (DNA-directed); delt 513.52 431 522.5153 P00519 I06ef5 v-abl Abelson murine leukemia v 232.4636 301 522.7624 Q13880 O02cd5 brain and reproductive organ-ex 572.4849 263 523.9906 P25789 L13ef7 proteasome (prosome; macropali 436.5895 534 526.397 O43805 J16cd3 Sjogren's syndrome nuclear auto 368.0123 539 526.5215 O75817 A13cd6 POP7 (processing of precursor; 375.1187 433 526.6432 Q9UBI1 N11cd7 BUP protein 337.1018 428 526.9646 P03950 G12ab2 angiogenin; ribonuclease; RNase 395.0198 200 527.7882 P78423 F20cd1 small inducible cytokine subfamily 201.965 747 530.2357 Q9P1D0 E07gh4 hypothetical protein PRO2533 58.04051 73.3 531.5331 P03999 K05ab3 opsin 1 (cone pigments); short-w 116.5093 37.9 532.8048 O95793 M22cd2 staufen; RNA binding protein (Dr 417.7687 498 534.8626 P22750 M05ef2 RAB4B; member RAS oncogene 297.3584 346 538.4665 B06gh8 ubiquitin UBF-fi 431.0731 472 540.8482 Q9NRX8 J15gh4 oxidoreductase UCPA 168.7047 523 544.0864 Q9UHQ3 J20gh4 stromal cell protein 469.8784 214 546.1893 Q96S52 J22gh8 phosphatidylinositol glycan; clas 404.9498 287 546.8906 Q9H3F6 C24gh8 MSTP028 protein 442.9007 396 549.0707 P37198 K03cd8 nucleoporin 62 kD 428.2961 499 550.8083 Q9H1D4 B05gh4 arginyl aminopeptidase (aminop 430.3273 477 551.8541 O75350 K04cd5 glycoprotein; synaptic 2 480.7082 436 552.8489 Q9P024 D16ef3 Huntingtin Interacting protein K 369.5132 480 553.5493 Q9Y224 H21ef2 CGI-99 protein 449.089 472 554.6607 Q13361 O12cd3 Microfibril-associated glycoprotel 194.28 354 557.066 Q02535 F01ef1 inhibitor of DNA binding 3; domir 84.05787 174 559.513 O95864 L24cd4 fatty acid desaturase 2 298.4502 113 559.6571 P53621 H16ab4 coatomer protein complex; subur 409.2779 471 560.6313 P35638 N03ab4 DNA-damage-inducible transcrip 322.5942 318 565.361 P22307 D22cd1 sterol carrier protein 2 354.3674 356 569.1558 Q92543 D15gh1 KIAA0254 gene product 328.3511 356 569.5472 P78330 N06ab8 phosphoserine phosphatase 253.4253 220 569.9825 Q9UNX3 G15ef2 ribosomal protein L26-like 1 401.3697 445 572.3441 P49189 C10ab2 aldehyde dehydrogenase 9 famil 446.252 277 579.314 Q9ULX0 H03gh6 inorganic pyrophosphatase 488.3446 402 579.6142 O15353 H21cd3 winged-helix nude 407.9375 497 580.6191 Q9NRP2 D21gh4 DC13 protein 382.8544 421 581.5421 Q16280 E18ef1 cyclic nucleotide gated channel 464.0608 360 584.8035 P04183 C04cd2 thymidine kinase 1; soluble 346.7317 289 588.3101 Q12824 O17ef5 SWI/SNF related; matrix associa 218.8831 554 590.2326 Q99719 B09ab8 peanut-like 1 (Drosophila) 419.5269 410 592.2598 P46100 H07ab3 alpha thalassemia/mental retard 309.8648 167 594.3041 Q16610 O05ab5 extracellular matrix protein 1 238.3172 335 596.1691 P39656 E23ab6 dolichyl-diphosphooligosacchari 433.6719 367 598.0668 P53814 G07cd3 smoothelin 517.4102 269 598.16 Q9P0N4 P24ef1 hypothetical protein LOC51260 609.9142 286 601.9324 Q9BXZ1 A02gh7 peptidylprolyl isomerase (cyclopt 465.4301 362 603.8737 Q9Y2Q4 H19ef8 HSPC002 protein 337.5615 391 604.9187 O15527 A18ab8 8-oxoguanine DNA glycosylase 330.4852 282 605.3444 Q04323 G01ef2 ORF 497.159 255 610.1121 P12004 G18ab8 proliferating cell nuclear antigen 332.1465 303 612.821 Q99720 M11cd6 sigma receptor (SR31747 binding 363.8609 379 615.0729 P43307 G13cd2 signal sequence receptor; alpha 226.1566 322 618.9554 Q9H3Y8 O05gh6 chromosome 20 open reading fra 221.2984 246 619.4944 Q9NRX2 A08gh5 mitochondrial ribosomal protein 284.6282 305 627.9834 Q9P2X0 L10gh2 dolichyl-phosphate mannosyltran 285.542 431 638.6696 Q9Y5Z8 E05cd7 male-specific lethal 3-like 1 (Dro 361.7331 394 639.7431 P78524 F01cd2 suppression of tumorigenicity 5 343.4117 289 643.333 P55145 F02ab2 arginine-rich; mutated in early st 413.1582 420 656.6324 P33551 O23ab5 CDC28 protein kinase 1 296.3533 355 671.4891 Q9BVQ0 E09gh6 hypothetical protein MGC5363 43.30788 54.5 681.2449 P34897 D15cd2 serine hydroxymethyltransferase 440.9652 290 685.6584 Q9Y5B4 L23ef2 androgen induced protein 268.4081 519 685.9395 Q9Y2V5 B15ef2 transforming growth factor beta 1 249.1479 327 712.3879 Q13953 B19cd2 solute carrier family 12 (potassiu 342.5865 428 729.2688 Q92686 I11ef6 neurogranin (protein kinase C su 330.8792 299 736.2348 O60565 J05cd8 cysteine knot superfamily 1; BMF 106.6904 151 781.0154 Q9Y4M4 I21gh3 putative UDP-GalNAc:polypeptid 346.098 251 846.4309 P16581 E01ef7 selectin E (endothelial adhesion 109.3094 378 875.1666 O14733 P02ef5 mitogen-activated protein kinase 98.83312 140 888.014 Q16623 M24cd2 syntaxin 1A (brain) 403.2337 165 926.5022 Q9P1M5 P12gh3 WW domain containing oxidored 38.93 19.3 1292.23 O60613 L18cd4 15 kDa selenoprotein 1220.902 1110 1285.07 Q16698 M07ab4 2:4-dienoyl CoA reductase 1; mit 469.9997 706 615.3087 Q9HBA8 D23gh1 24-dehydrocholesterol reductase 768.0888 278 626.0195 Q9P0I2 M13ef4 30 kDa protein 546.352 691 614.5795 Q9UL53 P24cd7 5′-3′ exoribonuclease 2 648.132 604 430.2235 P49902 N16cd7 5′-nucleotidase; cytosolic II 1040.523 1220 440.0817 O95336 P09cd7 6-phosphogluconolactonase 524.3104 755 812.5955 Q03393 A23ab8 6-pyruvoyltetrahydropterin synth 358.0591 700 517.4335 Q13443 P01ef7 a disintegrin and metalloproteina 1306.754 481 445.3663 O75173 F15ab2 a disintegrin-like and metalloprot 786.5151 1060 1254.804 P51572 O03gh1 accessory proteins BAP31/BAP2 985.1381 889 656.6554 P42765 D03ab2 acetyl-Coenzyme A acyltransfera 849.6041 1280 1204.131 P24666 E05ab2 acid phosphatase 1; soluble 1642.966 1970 1890.909 Q92688 D21cd6 acidic (leucine-rich) nuclear phos 470.8575 289 835.9103 O14639 B21ab2 actin binding LIM protein 1351.973 393 358.779 O15143 F06ab2 actin related protein 2/3 complex 696.0033 513 349.0474 O15509 F12ab2 actin related protein 2/3 complex 909.0832 889 807.751 O15511 F14ab2 actin related protein 2/3 complex 732.1996 619 466.1372 P12718 A08ab6 actin; gamma 2; smooth muscle; 585.3438 846 2095.96 Q9P0I6 O09ef4 AD-015 protein 947.0386 837 1259.571 O43747 M13ab2 adaptor-related protein complex 1104.332 532 419.4712 P20172 A11ab6 adaptor-related protein complex: 1286.83 1280 2285.193 O14617 H07ab2 adaptor-related protein complex: 679.4847 495 357.0868 P07741 M24ab2 adenine phosphoribosyltransfera 1885.065 862 823.8455 P00568 A02ab2 adenylate kinase 1 2404.119 399 354.3768 Q9U1J7 I06ef2 adenylate kinase 3 alpha like 758.7288 1060 662.8834 P30566 M07ab2 adenylosuccinate lyase 495.8874 622 518.4238 Q16186 M11cd7 adhesion regulating molecule 1 622.3901 610 574.5888 Q9NVF6 B19gh3 ADP-ribosylation factor 1 GTPas 449.3679 623 676.1878 P26438 B04ab2 ADP-ribosylation factor 6 732.1241 818 876.9277 P40616 D12ab2 ADP-ribosylation factor-like 1 827.1898 1220 1141.92 P36404 D14ab2 ADP-ribosylation factor-like 2 1751.048 1550 1871.661 P56559 D20ab2 ADP-ribosylation factor-like 7 485.4562 598 568.6824 P35368 K17ab2 adrenergic; alpha-1B: receptor 1433.715 1510 1335.995 P15144 G24ab2 alanyl (membrane) aminopeptida 987.3343 222 480.1162 P30038 L09ab2 aldehyde dehydrogenase 4 famil 1179.797 598 657.4315 P14550 L05ab2 aldo-keto reductase family 1: me 555.464 886 609.9901 O43488 L07ab2 aldo-keto reductase family 7: me 546.409 525 748.5424 P09972 C16ab2 aldolase C; fructose-bisphospha 878.5714 1050 947.5062 O43590 G12ef4 alpha-actinin-2-associated LIM p 776.3757 1070 501.1993 Q08117 M19ab2 amino-terminal enhancer of split 1779.707 1430 1219.695 Q13438 G05cd7 amplified in osteosarcoma 658.0513 638 802.3407 O96018 M01gh1 amyloid beta (A4) precursor prot 762.3898 750 1117.682 Q13564 P11ab2 amyloid beta precursor protein bi 587.5144 664 786.6426 Q9Y679 B08cd7 ancient ubiquitous protein 1 1191.741 1270 1022.771 Q9UKB4 B12ef2 angiomotin like 2 523.7253 776 568.8766 Q13725 H19ab2 angiotensin receptor 1 1495.332 1360 1058.942 P08133 I20ab2 annexin A6 253.0936 413 879.9474 P20073 I22ab2 annexin A7 650.1591 481 420.4945 P03971 E22ab2 anti-Mullerian hormone 1140.812 948 640.7158 P30041 O08cd5 anti-oxidant protein 2 (non-seleni 1248.922 1160 3067.945 P27695 K06ef6 APEX nuclease (multifunctional 665.9854 653 835.6897 Q9Y4J7 P01ab2 apoptosis inhibitor 5 1850.534 68.4 147.4186 Q9Y5L7 L03ef2 apoptosis related protein APR-3 662.9122 583 1426.489 O94778 O14ab2 aquaporin 8 1475.036 1420 1474.307 O15296 E02ab2 arachidonate 15-lipoxygenase; s 826.8209 607 720.2105 P48444 O18ab2 archain 1 1291.871 1200 1374.223 P00966 J24ab2 argininosuccinate synthetase 1049.688 1600 949.4889 P42024 D15ab2 ARP1 actin-related protein 1 hon 1054.286 1720 1777.944 O43681 J16ab2 arsA arsenite transporter; ATP-bi 540.3448 724 595.3348 Q9ULX3 E02ef4 ART-4 protein 728.7274 595 509.3934 O96030 H16ab2 arternin 881.7849 728 638.2016 P15289 F24ab2 arylsulfatase A 1639.546 1230 1012.121 P08243 J18ab2 asparagine synthetase 891.3027 643 1540.113 O95630 L17ab2 associated molecule with the SH 660.3522 872 729.2383 O95135 B09ab2 ataxin 2 related protein 902.4529 345 342.3299 O14530 N15ab2 ATP binding protein associated v 827.4646 1390 766.257 P30049 N20ab2 ATP synthase; H+ transporting; r 625.0408 468 441.4691 Q9UII2 I10ef2 ATPase inhibitor precursor 776.4612 1220 641.2787 Q9Y5K8 F17ef2 ATPase; H+ transporting; lysoso 998.0597 1670 1029.886 O75787 P15ab2 ATPase; H+ transporting; lysoso 815.707 945 1081.688 P05023 P09ef5 ATPase; Na+/K+ transporting; al 1299.236 517 709.0882 P45844 P13ef5 ATP-binding cassette; sub-family 863.8068 381 606.1642 Q9HAP7 M08gh5 baculoviral IAP repeat-containing 1507.175 1740 1945.196 O94812 G09ab3 BAI1-associated protein 3 1073.67 983 826.6524 P35613 B14ef7 basigin (OK blood group) 603.4821 474 865.2409 Q9BSR6 A20gh8 BBP-like protein 1 816.219 1320 914.1927 O00512 K01ab3 B-cell CLL/lymphoma 9 1357.15 76.7 80.36541 Q12983 E19ab5 BCL2/adenovirus E18 19 kD inte 763.7046 548 991.4529 Q92934 K24ef1 BCL2-antagonist of cell death 538.8191 727 603.5103 Q07817 E10ef6 BCL2-like 1 2062.673 2510 1097.372 O43892 M23ab3 Bicaudal D homolog 1 (Drosophil 654.9397 414 548.7409 P53004 O19ab3 biliverdin reductase A 490.0724 569 512.2807 O60629 G21ab3 bladder cancer associated protei 607.9847 1180 1083.411 Q9HBX3 N21gh6 brain and nasopharyngeal carcin 1672.876 54 44.02379 P56945 H23ef3 breast cancer anti-estrogen resis 1334.88 1300 1304.356 O15255 G21cd6 CAAX box 1 733.6878 577 1202.182 P12830 C16ef5 cadherin 1; type 1; E-cadherin (e 1094.64 924 489.5012 P19022 E03ef7 cadherin 2; type 1; N-cadherin (n 337.5528 540 747.1198 P22223 K19ef7 cadherin 3; type 1; P-cadherin (p 896.8467 1200 372.3054 P22676 N07ab5 calbindin 2; (29 kD; calretinin) 1781.134 1500 2116.438 Q99828 O19gh1 calcium and integrin binding 1 (c 1130.551 1320 838.3709 P02593 I18ab4 calmodulin 1 (phosphorylase kin 1076.299 787 983.6302 Q13942 L01ab5 calmodulin 3 (phosphorylase kin 902.667 464 871.1455 P27824 I05ef1 calnexin 1492.644 1370 1543.709 P17655 C20ef6 calpain 2; (m/ll) large subunit 671.5939 837 549.4365 P04632 C22ef6 calpain; small subunit 1 1565.935 1650 1258.047 Q15417 P17ab5 calponin 3; acidic 911.495 603 737.1204 Q9UEG5 D17ef8 capicua homolog (Drosophila) 629.0213 486 439.6052 P52907 O08ab4 capping protein (actin filament) n 848.0436 684 584.7035 Q9GZX3 N16gh1 carbohydrate (N-acetylglucosami 793.1054 929 751.3352 Q16619 K01ab4 cardiotrophin 1 1478.249 1220 1559.477 Q9UBD9 I24cd8 cardiotrophin-like cytokine; neur 361.4077 893 489.6592 Q15699 M16cd4 cartilage paired-class homeopro 747.0317 596 1109.834 P48729 A22ab6 casein kinase 1; alpha 1 690.8551 1150 902.9474 P48730 L07ab4 casein kinase 1; delta 951.5238 1160 1111.571 P19138 L08ef5 casein kinase 2; alpha 1 polypep 483.6062 597 461.8036 P49662 C12ef6 caspase 4; apoptosis-related cys 2013.957 2460 1017.425 P21964 F19ef6 catechol-O-methyltransferase 697.5886 1170 1268.869 P26232 K01ef7 catenin (cadherin-associated pro 797.8639 717 810.257 P35222 G07ef7 catenin (cadherin-associated pro 969.252 1290 1103.619 P07339 N23ef7 cathepsin D (lysosomal aspartyl 1253.01 947 1133.879 Q99967 C18cd6 Cbp/p300-interacting transactiva 1293.915 1600 2245.133 P49715 N17ef6 CCAAT/enhancer binding protei 882.9323 884 1045.45 P53567 N22ab5 CCAAT/enhancer binding protei 826.9569 1160 1584.869 O95627 B21cd8 CCR4-NOT transcription comple 606.4629 851 692.4535 Q04900 G02cd4 CD164 antigen; sialomucin 750.3086 570 673.7234 P07766 P07ab3 CD3E antigen; epsilon polypepti 1808.209 1410 2643.721 P34810 A21ab4 CD68 antigen 2460.227 1100 1293.961 P18582 B21ab5 CD81 antigen (target of antiprolif 1303.144 938 1598.276 Q16181 F09ef5 CDC10 cell division cycle 10 hon 426.6642 443 751.3623 Q16543 H01ef5 CDC37 cell division cycle 37 hon 1085.897 1050 1336.155 O14735 I14cd6 CDP-diacylglycerol-inositol 3-ph 241.7793 1180 311.7422 P30260 F13ef5 cell division cycle 27 1060.812 1470 1469.824 P49427 B12ef7 cell division cycle 34 762.5808 1300 766.6843 P29373 F01ef7 cellular retinoic acid binding prot 1226.236 803 1350.177 P41208 F09ab5 centrin; EF-hand protein; 2 539.1633 672 676.8582 O00522 F05ab4 cerebral cavemous malformation 870.4309 631 723.1482 O15183 B12cd3 CGG triplet repeat binding protei 402.949 610 883.3283 Q9Y2Z5 D07ef2 CGI-06 protein 721.6709 674 1177.641 Q9Y3C3 J05ef2 CGI-120 protein 1229.537 1360 2124.304 Q9Y3D0 J11ef2 CGI-128 protein 1592.767 2370 2011.685 Q9Y3E5 J17ef2 CGI-147 protein 532.425 788 567.0634 Q9Y3E8 C08ef2 CGI-150 protein 785.276 924 778.0449 Q9Y320 A19ef2 CGI-31 protein 745.0314 932 703.7829 Q9Y357 P16ef1 CGI-40 protein 817.7272 769 418.6337 Q9Y360 A10ef2 CGI-45 protein 786.0567 914 796.6229 Q9Y512 B04ef3 CGI-51 protein 967.3508 859 1045.638 Q9Y390 K21ef2 CGI-81 protein 1391.902 802 1140.01 P40227 N20ab4 chaperonin containing TCP1; su 1011.613 436 592.4944 Q99832 H07cd6 chaperonin containing TCP1; su 1190.644 1090 1548.874 Q9UBR5 I23ef4 chemokine-like factor 1 1047.63 1800 1059.437 Q9UHN8 N05ef4 chemokine-like factor 1 1568.851 2030 1237.728 P54105 L07ef5 chloride channel; nucleotide-sen: 471.0775 487 640.6855 Q14781 F09ef1 chromobox homolog 2(Pc class I 795.873 749 713.815 Q9BXS4 K12cd5 chromosome 1 open reading frar 874.0189 1370 904.3066 Q9NPA0 H07gh4 chromosome 11 hypothetical pro 998.8577 834 858.794 Q9UKR5 G14cd7 chromosome 14 open reading fra 1181.962 1160 1285.11 P56378 M16cd5 chromosome 14 open reading fra 503.5233 690 890.9975 O95433 B22cd7 chromosome 14 open reading fra 656.1775 563 438.9755 Q9NV31 J23gh3 chromosome 15 open reading fra 853.8367 832 861.2221 Q9NVE2 D09gh3 chromosome 2 open reading frar 648.49 671 468.6352 Q9UI05 L04gh4 chromosome 20 open reading fra 2518.951 2140 1201.051 Q9P0A7 M09ef8 chromosome 20 open reading fra 581.9098 1080 1200.665 Q9Y3B1 H22ef1 chromosome 20 open reading fra 1691.864 1230 783.7799 Q9BQ89 C01gh8 chromosome 20 open reading fra 1460.875 952 1221.732 Q96C58 J19gh7 chromosome 6 open reading frar 1254.647 1080 480.9999 Q9Y5Z4 K12ef3 chromosome 6 open reading frar 915.3818 988 372.3119 Q00610 I12cd5 clathrin; heavy polypeptide (Hc) 1639.759 1210 1437.44 P56749 F04cd7 claudin 12 2262.278 2480 1233.472 O43809 M15cd7 cleavage and polyadenylation sp 640.2301 503 683.3467 O96005 G05ab4 cleft lip and palate associated tre 1353.338 1170 1394.845 Q16740 E20cd4 ClpP caseinolytic protease; ATP- 625.8711 528 475.0848 P55085 O24ab5 coagulation factor II (thrombin) re 829.7537 979 392.7495 P13726 B05ab4 coagulation factor III (thrombopla 1079.841 880 442.6212 Q9Y678 D14ef8 coat protein gamma-cop 815.7993 738 1009.756 Q15363 M11ef3 coated vesicle membrane protein 706.3054 804 870.2118 O43513 N06cd4 cofactor required for Sp1 transcri 591.8619 481 798.8706 Q9Y281 N18cd8 cofilin 2 (muscle) 671.9394 270 1093.534 P04141 G22gh6 colony stimulating factor 2 (gran 116.2139 1290 165.718 P02745 L06ef1 complement component 1; q sub 683.4431 1650 798.2366 P29279 I16ab4 connective tissue growth factor 596.4123 537 1071.517 O43191 B02cd3 COP9 constitutive photomorphog 855.8616 1030 1302.334 Q99627 C01cd7 COP9 homolog 788.2297 968 1195.497 O15387 G21cd7 COP9 subunit 6 (MOV34 homolo 590.9973 382 628.5041 Q9ULV4 K18ef3 coronin; actin binding protein; 1C 1594.037 1200 1362.545 Q9BR76 I14gh7 coronin; actin-binding protein; 1E 708.5653 1080 690.8568 Q14061 B22cd5 COX17 homolog; cytochrome c c 889.1581 1440 745.8658 Q9Y6B2 E02ef8 CREBBP/EP300 inhibitory protei 946.9513 1030 1988.725 Q9NY68 C06gh4 CTL2 gene 1381.821 804 788.5002 P24385 O04ef5 cyclin D1 (PRAD1: parathyroid a 1214.611 2150 1100.478 Q9NXT4 K09gh2 cyclin M2 1560.659 1720 1582.768 P01034 I11ab6 cystatin C (amyloid angiopathy a 1067.127 970 1366.396 Q15828 I13ab4 cystatin E/M 967.1669 2790 451.3932 P01036 C02ab6 cyctatin S 1261.605 466 1069.756 P52943 I05ab4 cysteine-rich protein 2 874.1939 499 1277.819 P13498 G18ab3 cytochrome b-245; alpha polyper 708.9954 1050 359.3156 P00167 C04ab6 cytochrome b-5 2187.128 1480 1034.311 P00001 N24gh6 cytochrome c 547.6708 442 517.6125 P10606 I24gh6 cytochrome c oxidase subunit Vb 1364.01 2100 2087.456 P08574 P10ab5 cytochrome c-1 667.9346 443 441.6771 Q99426 C17gh1 cytoskeleton-associated protein 560.9411 684 777.3269 Q07065 G13cd7 cytoskeleton-associated protein 602.5101 575 1785.415 Q15038 L13ef3 DAZ associated protein 2 808.0755 890 564.7611 Q9H2L4 B18gh8 DC32 408.0427 702 780.2878 Q9NPA8 G22gh7 DC6 protein 944.3094 1570 1514.164 O60231 H13cd3 DEAD/H (Asp-Glu-Ala-Asp/His) t 753.8815 873 799.6561 Q9GZR7 E02gh4 DEAD/H (Asp-Glu-Ala-Asp/His) t 803.42 984 774.3765 P17844 F04ab4 DEAD/H (Asp-Glu-Ala-Asp/His) t 1482.642 1440 1670.104 Q08211 M03ab4 DEAD/H (Asp-Glu-Ala-Asp/His) t 907.5859 658 907.4343 Q9UJV9 D08ef2 DEAD-box protein abstrakt 976.8378 1230 870.3672 P51398 G18ef6 death associated protein 3 920.3044 981 814.3518 Q13437 G22cd4 Deleted in split-hand/split-foot 1 1565.344 1500 1721.872 O60735 O06cd6 dendritic cell protein 858.6375 502 467.3432 Q16854 M06ab5 deoxyguanosine kinase 858.1918 885 989.3036 Q9Y295 H04ab8 developmentally regulated GTP I 736.3786 634 660.7023 P00387 F09ab3 diaphorase (NADH) (cytochrome 1402.134 1030 1435.74 Q9UHY9 I08ef2 dicarbonyl/L-xylulose reductase 544.2125 740 938.7807 P36957 C06ab6 dihydrolipoamide S-succinyltrans 625.9037 713 393.7165 Q99075 M12ef7 diphtheria toxin receptor (hepari 721.8431 638 197.117 Q9UFN1 H10gh6 DKFZP564B147 protein 966.5927 947 1469.105 O95882 C13ef8 DKFZP564C1940 protein 941.4076 865 804.639 Q9Y269 C07ef8 DKFZP564M082 protein 675.8991 1110 1208.543 Q9NWE3 J11ef8 DKFZP566C243 protein 419.5607 770 625.8483 Q9H6Y7 H04gh6 DKFZP566H073 protein 1390.389 1480 1191.195 Q9Y3X0 P23ef8 DKFZP586M1019 protein 588.3603 505 672.4872 O60762 G19cd4 dolichyl-phosphate mannosyltran 407.0059 581 605.8353 P53805 B11ab5 Down syndrome critical region g 370.0907 663 511.9248 Q13597 N13ef3 downregulated in ovarian cancer 594.6931 693 623.702 Q9C005 J05gh8 dpy-30-like protein 810.4585 1210 1174.001 Q13448 J03cd6 DR1-associated protein 1 (negati 1240.359 1140 2382.895 Q9UHF9 K01ef4 dual oxidase 2 1146.14 648 316.6462 P51452 N22ab4 dual specificity phosphatase 3 (v 649.6813 605 473.5652 Q14203 A13ab6 dynactin 1 (p150; glued homolog 507.5942 529 623.6948 Q13561 D19cd6 dynactin 2 (p50) 1565.567 1380 1173.024 Q13409 I16ef1 dynein; cytoplasmic; intermediate 793.3207 604 464.9675 Q09472 C18ab4 E1A binding protein p300 1496.409 2120 1342.944 D20gh8 EAF1 protein 642.1587 652 469.6834 P78365 N19ab4 early development regulator 2 (p 894.3715 1070 761.5923 Q99848 G11cd7 EBNA1 binding protein 2 977.8671 611 818.6583 Q12805 A21ab6 EGF-containing fibulin-like extra 1002.82 332 458.9563 Q9Y6I3 D21cd8 EH domain-binding mitotic phosp 736.8984 500 629.1845 Q15717 C04ab4 ELAV (embryonic lethal; abnorm 850.8493 800 843.4463 P13804 I24ab3 electron-transfer-flavoprotein; alp 918.8391 545 529.2866 Q14247 K17ef6 ems1 sequence (mammary tumo 1135.188 1050 1002.084 P42892 O21ab4 endothelin converting enzyme 1 602.4294 799 809.7071 P30084 A17ab6 enoyl Coenzyme A hydratase; sh 802.3114 1210 741.2226 P07099 I20ab3 epoxide hydrolase 1; microsomal 1231.48 1840 1198.169 P29692 H04ab5 eukaryotic translation elongation 1329.756 744 1110.87 P20042 L05cd4 eukaryotic translation initiation fa 1489.433 603 956.276 P41091 A20ab4 eukaryotic translation initiation fa 742.5843 474 478.7249 Q99613 L16cd3 eukaryotic translation initiation fa 1140.022 853 998.7488 P78344 C02ab4 eukaryotic translation initiation fa 1562.952 1520 1177.845 P23588 A24ab4 eukaryotic translation initiation fa 1343.019 1010 1125.825 Q13541 C03ab5 eukaryotic translation initiation fa 1655.926 1060 2293.236 Q13542 A19ab6 eukaryotic translation initiation fa 1620.111 1850 1663.197 O60573 G16cd5 eukaryotic translation initiation fa 799.7789 883 819.3679 Q16394 K02ab3 exostoses (multiple) 1 513.7526 428 813.2693 P37268 C17ab6 famesyl-diphosphate famesyltra 726.0862 455 649.0518 P55899 L22ab5 Fc fragment of IgG; receptor; tra 450.8629 771 476.1039 Q9UK73 P05ef3 fem-1 homolog b (C. elegans) 548.2677 547 530.801 P21333 G14ab4 filamin A; alpha (actin binding pr 946.0465 675 1277.458 P26885 P07ab4 FK506 binding protein 2 (13 kD) 814.6357 510 661.4593 Q13451 F15ab4 FK506 binding protein 5 1366.905 1110 812.8568 O95633 M01cd6 follistatin-like 3 (secreted glycop 1312.174 1280 1092.99 P15407 A20cd4 FOS-like antigen 1 1696.135 1350 1218.491 Q14192 G02ab4 four and a half LIM domains 2 309.9219 591 1210.635 Q9NZA0 N17gh6 fuse-binding protein-interacting 924.2347 911 1110.468 P35637 P19ab4 fusion; derived from t(12; 16) mali 866.3996 654 1159.792 E21gh7 FXYD domain-containing ion tra 942.6126 1060 802.8679 Q9Y653 B02cd5 G protein-coupled receptor 56 2010.489 2160 1501.617 Q9H1C0 E18gh4 G protein-coupled receptor 92 712.1007 750 719.7999 P15170 L13ab4 G1 to S phase transition 1 2042.425 1410 1109.721 O95166 D09cd7 GABA(A) receptor-associated pr 1280.495 2210 1227.378 O08765 D21cd7 GABA(A) receptor-associated pr 1241.27 1130 918.8337 P16278 O05ef1 galactosidase; beta 1 539.4222 800 656.0518 P78537 J23ab4 GCN5 general control of amino- 813.3309 637 919.5196 P31150 F14ab4 GDP dissociation inhibitor 1 633.6157 894 640.108 P06396 B23ab3 gelsolin (amyloidosis; Finnish typ 330.1567 577 633.2269 P52657 E03ab6 general transcription factor IIA; 2 538.6557 685 700.1857 Q00403 F08ef6 general transcription factor IIB 500.4565 791 454.8328 P48060 I23cd7 glioma pathogenesis-related pro 676.4844 692 752.7928 P06744 B19ab3 glucose phosphate isomerase 900.9772 553 726.4749 P30101 G13ab5 glucose regulated protein; 58 kD 1708.658 1250 2220.105 O43836 I22ef1 glutamate receptor; ionotropic; N 1729.777 1890 1655.131 P15104 H22ab5 glutamate-ammonia ligase (gluta 1170.59 1040 1180.088 Q06210 A23ab5 glutamine-fructose-6-phosphate 869.494 600 863.157 Q9Y3D4 M19ef2 glutaredoxin 2 888.5406 894 1099.209 Q9Y2Q3 C24ef2 glutathione S-transferase subuni 841.3959 346 414.7892 P48637 D01ab3 glultathione synthatase 650.8496 429 488.6663 P78417 E20cd5 glutathione-S-transferase like; gl 1983.626 2020 1805.489 P49840 J14ef4 glycogen synthase kinase 3 alph 1057.368 1460 1247.816 P13224 F23ab3 glycoprotein lb (platelet): beta pc 487.4684 530 653.4727 Q9UBQ7 L08cd7 glyoxylate reductase/hydroxypyn 947.0262 977 997.593 Q9P2T1 C02ef2 GMPR2 for guanosine monopho 762.0126 1070 817.0496 Q9H4A6 I04gh5 golgi phosphoprotein 3 (coat-pro 1027.603 1210 1209.783 P28799 B19ab5 granulin 1611.298 1750 1238.745 Q14393 H10ab3 growth arrest-specific 6 484.489 563 739.1661 P29354 H06ef5 growth factor receptor-bound pro 721.5894 854 663.0587 Q14451 D20ab4 growth factor receptor-bound pro 712.3296 846 636.8962 Q9Y6G2 E04ef8 growth hormone inducible trans 1289.256 1020 974.263 P04899 J09ab4 guanine nucleotide binding prote 860.9208 1390 1748.649 P11016 M13ef5 guanine nucleotide binding prote 758.629 773 836.6295 Q13905 G09ab6 guanine nucleotide-releasing fac 410.0949 569 535.1889 Q16774 L16ab3 guanylate kinase 1 968.5867 1340 975.8911 Q9Y649 K16ef4 GW128 protein 1663.305 2420 1834.174 P07305 G13ab6 H1 histone family; member 0 1780.353 1870 1746.555 O75367 M14cd5 H2A histone family; member Y 1065.311 837 455.5967 P17317 C24ab6 H2A histone family; member Z 591.0013 461 1570.489 P02278 M16gh6 H2B histone family; member G 586.8773 852 684.6287 Q9NS37 A03gh5 HCF-binding transcription factor 857.3143 717 601.7268 O96004 E02cd5 heart and neural crest derivatives 705.5163 612 621.033 P10809 M11ef5 heat shock 60 kD protein 1 (chap 1693.23 1020 1276.41 P34932 I11ef1 heat shock 70 kD protein 4 1402.505 1610 1042.113 P07900 G18ef7 heat shock 90 kD protein 1; alpha 2405.793 1430 1512.258 P08238 B20ab7 heat shock 90 kD protein 1; beta 2781.462 1950 979.1145 O75506 H17ab6 heat shock factor binding protein 1132.126 1300 1081.748 Q9UHG4 K18ef4 heme-regulated initiation factor 2 413.2841 659 576.3971 P09105 J21ab4 hemoglobin; theta 1 702.445 484 769.2336 O43504 D23cd6 hepatitis B virus x interacting pro 1008.655 1340 949.0116 Q9H2I6 N10gh5 hepatitis C virus core-binding pro 676.7297 620 473.9328 P51858 K16ef7 hepatoma-derived growth factor 894.1008 1170 490.7458 Q04150 A08ab7 heterogeneous nuclear ribonucle 943.3857 870 1065.597 Q13151 E15cd7 heterogeneous nuclear ribonucle 906.986 944 1143.552 P22626 N09ab6 heterogeneous nuclear ribonucle 1021.87 1010 1584.855 P07910 A10ab7 heterogeneous nuclear ribonucle 747.5309 718 1059.349 O14979 L09cd5 heterogeneous nuclear ribonucle 1057.699 1990 1646.172 P52597 G06ab7 heterogeneous nuclear ribonucle 1902.939 1280 1517.274 Q07244 N13ab6 heterogeneous nuclear ribonucle 847.6967 667 684.4978 Q15584 P03ab7 heterogeneous nuclear ribonucle 725.3651 569 858.2829 P12081 J12ab4 histidyl-tRNA synthetase 555.5578 565 424.3904 Q9UBN7 E11cd6 histone deacetylase 6 685.5336 407 695.1552 Q13838 M07cd4 HLA-B associated transcript 1 681.4666 604 921.7532 Q99873 H02ef7 HMT1 hnRNP methyltransferase- 890.1184 836 1209.872 Q9H063 M14gh8 homolog of yeast MAF1 744.9951 921 1013.86 P51610 L21ab5 host cell factor C1 (VP16-access 583.7478 580 735.1691 O00165 I04cd6 HS1 binding protein 1482.068 1490 2425.818 Q9Y2Q5 P24ef7 HSPC003 protein 620.7783 1010 625.6574 Q9Y2R0 A05ef8 HSPC009 protein 1507.005 1720 1784.568 Q9Y2T0 A17ef8 HSPC022 protein 453.0964 733 326.4215 Q9UNZ5 C17ef8 HSPC023 protein 825.3888 1310 1347.488 Q9P032 O19ef8 HSPC125 protein 558.8905 602 843.0953 Q9P019 A06ef8 HSPC141 protein 717.9096 1700 1519.292 Q9P004 A24ef8 HSPC160 protein 1182.006 1070 545.8523 Q9P003 C04ef8 HSPC163 protein 801.5204 1410 1148.378 Q9P000 C06ef8 HSPC166 protein 508.2074 921 523.3806 Q9Y684 N09ef2 HSPCO34 protein 569.9533 628 797.4819 Q9NRG2 D01gh4 HTGN29 protein 1276.132 1470 1639.451 Q16775 G15ab6 hydroxyacyl glutathione hydrolas 511.3412 676 407.0538 P40939 D07ab3 hydroxacyl-Coenzyme A dehydr 1814.498 1770 1617.578 P55084 D09ab3 hydroxacyl-Coenzyme A dehydr 539.2691 890 1218.105 Q14526 B13ab5 hypermethylated in cancer 1 918.3678 904 1008.759 Q9UBS2 A15ef1 hyperpolarization activated cyclic 676.9289 688 520.6835 Q96EW8 P08gh8 hypothetical gene ZD52F10 727.4433 605 223.8014 Q9Y2S6 D01ef2 hypothetical protein 1188.199 1490 1593.015 Q9UKZ1 I23gh3 hypothetical protein C40 657.2427 614 506.0272 Q9UJJ9 D21gh8 hypothetical protein CAB56184 432.491 695 601.25 O95891 D08ef8 hypothetical protein CL25022 1675.198 2070 1477.523 Q9UJI9 F08gh6 hypothetical protein DJ328E19.C 1119.481 935 1005.691 Q9H0U3 K20gh8 hypothetical protein DKFZp564K 1287.049 1080 1145.302 Q9NWD8 N05gh2 hypothetical protein FLJ10099 754.9838 758 710.8818 Q9NW90 P21gh2 hypothetical protein FLJ10211 492.5962 551 601.7235 Q9NW61 B18gh2 hypothetical protein FLJ10297 772.0358 844 620.8513 Q9NW16 G04gh3 hypothetical protein FLJ10374 756.2846 543 467.9722 Q9NVZ3 G14gh3 hypothetical protein FLJ10420 437.615 702 362.923 Q9NVC3 D23gh3 hypothetical protein FLJ10815 1402.842 928 598.595 Q9H9K7 B10gh5 hypothetical protein FLJ12681 446.1454 657 593.5606 Q9H8H4 H06gh5 hypothetical protein FLJ12800 1058.023 775 1421.894 Q9P0R5 L02ef1 hypothetical protein FLJ14868 702.1841 684 1117.168 Q9NXQ4 M07gh3 hypothetical protein FLJ20113 1503.987 1520 1545.141 Q9NXI2 M21gh3 hypothetical protein FLJ20234 643.4985 877 178.0291 Q9NXD5 E18gh2 hypothetical protein FLJ20309 617.1482 1420 758.0334 Q9NX64 I16gh2 hypothetical protein FLJ20419 938.8958 825 981.6359 Q9NWX1 A20gh3 hypothetical protein FLJ20552 1366.306 1800 1533.352 Q9NWT8 D11gh2 hypothetical protein FLJ20608 980.6383 915 907.2393 Q9NWM3 C20gh3 hypothetical protein FLJ20739 381.202 593 689.893 Q9H7C7 D05gh5 hypothetical protein FLJ21044 si 551.5395 708 585.1487 Q9H6R6 J23gh5 hypothetical protein FLJ21952 425.3152 396 679.1125 Q9H673 F11gh5 hypothetical protein FLJ22548 si 1394.825 1220 530.5646 O95476 H15ef8 hypothetical protein HSA011916 1310.097 1040 1485.684 Q9Y244 B23ef2 hypothetical protein HSPC014 1668.101 1530 1243.802 Q9P022 P04ef2 hypothetical protein HSPC138 666.1765 521 643.5979 Q9P013 P06ef2 hypothetical protein HSPC148 916.5214 1450 1133.279 Q9P009 P14ef2 hypothetical protein HSPC155 1031.658 1330 662.2481 Q9P0S9 A19ef3 hypothetical protein HSPC194 1336.172 1570 1957.055 Q9NPI0 A23ef3 hypothetical protein HSPC196 280.0356 644 672.086 O95887 C18ef2 hypothetical protein LOC51061 777.5591 709 551.8354 Q9P0T9 K02ef2 hypothetical protein LOC51234 1224.056 1290 1457.544 Q9P0Q1 K10ef2 hypothetical protein LOC51248 376.8259 933 1014.441 Q9P0P0 K20ef2 hypothetical protein LOC51255 1301.286 2190 1904.375 Q9P0N9 K22ef2 hypothetical protein LOC51256 540.326 374 604.1319 Q9NZD9 M23ef2 hypothetical protein LOC51323 600.1582 715 506.8479 O75207 M02gh4 hypothetical protein LOC57019 663.8685 644 680.7704 Q9BWL0 L24gh7 hypothetical protein MGC: 5244; 569.8856 436 732.9891 Q9BW61 C09gh6 hypothetical protein MGC2594 1446.395 2460 1354.586 Q9BQ49 K05gh6 hypothetical protein MGC2747 527.9287 679 677.2851 Q9BQD3 E17gh6 hypothetical protein MGC2749 841.5499 889 899.9017 Q9BQ61 A09gh6 hypothetical protein MGC2803 1234.395 2170 1980.421 Q9BTV4 O23gh6 hypothetical protein MGC3222 561.6572 502 583.5781 Q9BVX2 C17gh6 hypothetical protein MGC5576 747.2749 762 604.3725 Q9H773 I17gh6 hypothetical protein MGC5627 799.182 819 584.0079 Q9BPX5 L02gh7 hypothetical protein similar to ac 583.4076 424 632.4101 Q9UJX8 B09ef3 hypothetical protein; estradiol-in 1184.334 948 1116.899 P00492 P12cd6 hypoxanthine phosphoribosyltra 1210.895 233 566.0945 P22304 I04ab6 iduronate 2-sulfatase (Hunter sy 1197.3 1320 1095.895 Q03827 F02ef6 immediate early protein 650.6358 537 536.2705 P12268 F11ab6 IMP (inosine monophosphate) d 1254.916 567 1293.693 Q9Y6K9 P03cd3 inhibitor of kappa light polypepti 822.3859 788 807.6888 Q14573 F04ab6 inositol 1;4;5-triphosphate recep 555.9397 646 627.6143 O15357 L09ab6 inositol polyphosphate phosphat 997.7512 1150 1290.473 O15503 B05ab7 insulin induced gene 1 472.0202 428 615.7553 P52945 L13gh8 insulin upstream factor 1 1437.285 3700 746.514 P51460 B07ab7 insulin-like 3 (Leydig cell) 1227.459 1290 1040.851 P46977 D20ab6 integral membrane protein 1 1693.474 1790 2514.977 Q13418 H08ef5 integrin-linked kinase 1340.442 962 1599.336 P48551 O21ef7 interferon (alpha; beta and omeg 605.1613 669 389.178 P15260 A02ef7 interferon gamma receptor 1 1165.784 2600 1179.083 P38484 D12ef5 interferon gamma receptor 2 (int 593.6133 773 550.2678 O14896 K05ef6 interferon regulatory factor 6 495.9782 951 406.9438 G13ef5 interferon-gamma receptor (IFNG 616.4461 474 457.8757 Q14116 L03ab6 interleukin 18 (interferon-gamma 1525.444 1610 556.9614 O75874 H11ab7 isocitrate dehydrogenase 1 (NA 660.9773 496 904.897 P51553 I21gh1 isocitrate dehydrogenase 3 (NA 815.5318 899 784.1063 P41252 P23ab6 isoleucine-tRNA synthetase 643.6728 316 992.267 Q9UE89 J07ef7 jagged 2 657.9935 460 696.5019 P52292 J14ab6 karyopherin alpha 2 (RAG cohor 1105.911 1270 1670.406 P24390 E07cd7 KDEL (Lys-Asp-Glu-Leu) endopl 1556.771 1210 1411.383 P08779 D03ab7 keratin 16 (focal non-epidermoly 815.5106 786 663.0228 Q04695 O24ab6 keratin 17 580.3123 1180 1056.274 Q07666 B04cd6 KH domain containing: RNA bind 1212.816 780 1103.092 Q14165 O16gh1 KIAA0152 gene product 285.0232 348 1374.81 Q12765 F03gh1 KIAA0193 gene product 951.658 1000 981.6527 O43310 F11gh1 KIAA0427 gene product 482.1741 589 556.0999 O43167 J03gh1 KIAA0441 gene product 1398.244 982 1102.589 Q9H7D5 I18gh7 KIAA1191 protien 886.4026 1930 1061.302 Q9HD96 L03cd8 LAG1 longevity assurance homol 1319.272 798 1016.572 O00182 P04ab6 lectin; galactoside-binding: solub 760.6622 1300 527.6081 Q99538 B04ef7 legumain 464.5 517 1105.037 O95751 G01cd8 leucine zipper; down-regulated ir 874.8344 274 970.9239 O15468 P03ef4 leukocyte immunoglobulin-like re 826.8073 939 1120.204 Q9UBB4 I06cd8 like mouse brain protein E46 877.3997 623 692.5911 Q9UFW4 N17ef8 likely ortholog of rat golgi stackin 1680.361 1700 2121.05 Q14847 P09ab7 LIM and SH3 protein 1 664.6143 758 895.1972 O00158 M09ef3 LIM domain only 4 457.4088 299 1353.355 Q9HAP6 M16gh5 Lin-7b protein: likely ortholog of 2114.229 1550 2175.236 P38571 K08ab6 lipase A; lysosomal acid; cholest, 604.0401 587 512.8879 Q99732 I18cd5 LPS-induced TNF-alpha factor 680.3876 893 449.4711 Q9Y4Z1 O21ef4 Lsm3 protein 1641.224 1300 1596.905 O75896 D05cd7 lung cancer candidate 690.6061 772 601.3296 Q06643 O07ef6 lymphotoxin beta (TNF superfam 405.7368 1040 298.9254 O95372 J04ef7 lysophospholipase II 480.0562 737 752.7079 P13473 N06ab6 lysosomal-associated membrane 952.6393 2000 1277.773 Q08397 F09ab7 lysyl oxidase-like 1 1391.453 1630 2243.025 Q15046 B17ab7 lysyl-tRNA synthetase 900.8177 556 539.813 Q13312 D17cd3 MAD1 mitotic arrest deficient-like 807.7267 503 574.4266 Q09160 A05ab6 major histocompatibility complex; 1524.076 2710 1290.783 P40925 J23ab7 malate dehydrogenase 1; NAD ( 1144.218 788 1089.134 P40926 L01ab7 malate dehydrogenase 2; NAD ( 1525.837 1020 1212.544 Q16626 J15ef3 male-enhanced antigen 1253.21 1530 1827.301 Q9NQG1 C06gh5 mannosidase; beta A; lysosomal 533.2883 800 736.627 P26572 G11ab7 mannosyl (alpha-1;3-)-glycoprote 619.6733 369 887.6535 Q10469 G15ab7 mannosyl (alpha-1;6-)-glycoprote 600.1049 583 636.621 P41223 L09cd4 maternal G10 transcript 372.2443 563 575.7695 Q9Y5V3 G13cd6 melanoma antigen: family D; 1 397.4495 952 1674.881 P43121 I22ef5 melanoma cell adhesion molecu 886.0756 795 432.1718 Q92494 D11ef1 membrane cofactor protein (CD4 973.362 1050 834.044 Q14444 H15ab7 membrane component; chromos 549.4803 666 464.8174 Q9NPE2 O12ef2 mesenchymal stem cell protein C 749.8938 932 1085.26 Q92571 G07ab7 mesoderm specific transcript hon 617.581 446 537.1735 O95204 N11ef3 metalloprotease 1 (pitrilysin fam 735.157 349 478.8153 P80297 H20ab7 metallothionein 1L 589.6327 502 656.4441 Q99735 C18ef7 microsomal glutathione S-transfe 527.4698 686 373.9779 Q98XW5 D13gh8 microtubule-associated protein 1 247.2817 692 887.6299 Q9Y6C9 M14ef3 mitochondrial carrier homolog 2 1874.893 1910 1893.062 Q9Y3B7 E07ef2 mitochondrial ribosomal protein 1 401.0368 421 732.113 Q9P015 A12ef8 mitochondrial ribosomal protein 1 553.658 760 589.0617 Q9NX20 M06gh2 mitochondrial ribosomal protein 1 642.9143 496 701.1442 Q9H0U6 O13ef8 mitochondrial ribosomal protein 1 741.5383 1000 826.8816 Q9NZE8 O04ef2 mitochondrial ribosomal protein 1 914.9722 910 956.7888 Q9P0P3 K18ef2 mitochondrial ribosomal protein 1 1217.101 891 1196.143 Q9Y317 M15ef2 mitochondrial ribosomal protein 1 799.6979 1020 1372.352 Q9Y6G3 C19ef8 mitochondrial ribosomal protein 1 571.7264 810 689.3229 Q9BYC7 K12gh8 mitochondrial ribosomal protein 490.5463 665 619.0928 Q9Y3D3 B12ef1 mitochondrial ribosomal protein 966.7611 1020 1006.958 Q9Y676 C15ef8 mitochondrial ribosomal protein 683.2889 580 761.9887 Q9Y3D5 G19ef2 mitochondrial ribosomal protein 696.3306 1080 825.557 P82921 O11gh7 mitochondrial ribosomal protein 748.082 1190 1115.5 P82650 D07gh4 mitochondrial ribosomal protein 554.1784 515 470.683 Q9Y2Q9 A03ef8 mitochondrial ribosomal protein 1439.076 1420 1329.749 Q9NP92 F02ef3 mitochondrial ribosomal protein 669.1652 532 617.3223 Q02750 J08ef5 mitogen-activated protein kinase 615.689 701 453.8702 Q02779 K09ab7 mitogen-activated protein kinase 597.1743 423 509.6637 Q12851 N10ab8 mitogen-activated protein kinase 988.0971 1020 976.7391 P49137 J06ef5 mitogen-activated protein kinase 942.7459 1000 1068.579 Q9BYG3 O02gh8 MKI67 (FHA domain) interacting 791.8688 407 307.4404 Q15014 C17cd8 MORF-related gene X 1146.48 1030 1262.273 F22ef4 mRNA; clone: PO2ST9 1052.442 1040 905.2614 Q15773 M18ef5 myeloid leukemia factor 2 577.4585 467 766.6809 P35579 O01ef1 myosin; heavy polypeptide 9; no 1426.003 1150 1203.964 Q9Y6D2 C21ef2 N-acetyltransferase 5 (ARD1 ho 531.5485 708 274.9715 P41227 G13gh1 N-acetyltransferase; homolog of 800.6676 905 818.2554 Q13510 H20ab2 N-acylsphingosine amidohydrola 752.1534 1660 677.5006 O43678 O09ab7 NADH dehydrogenase (ubiquino 1366.754 1930 2137.906 O95167 E24ab7 NADH dehydrogenase (ubiquino 1431.655 1770 1506.934 P56556 O11ab7 NADH dehydrogenase (ubiquino 1650.612 916 795.8725 O95182 K06ab7 NADH dehydrogenase (ubiquino 750.0893 777 725.1711 P51970 L04cd8 NADH dehydrogenase (ubiquino 554.1995 728 1021.163 O96000 J10ab8 NADH dehydrogenase (ubiquino 1110.197 1440 1111.615 O95178 J06ab8 NADH dehydrogenase (ubiquino 925.3926 768 815.266 O95139 M03ab8 NADH dehydrogenase (ubiquino 1392.873 1480 2162.279 P17568 H02ab8 NADH dehydrogenase (ubiquino 787.0681 567 591.1924 Q9Y6M9 P16ab8 NADH dehydrogenase (ubiquino 1299.803 1450 746.8017 O43677 M05ab8 NADH dehydrogenase (ubiquino 586.5059 601 532.551 O00217 M09ab8 NADH dehydrogenase (ubiquino 1383.411 1130 1194.001 P19404 M07ef1 NADH dehydrogenase (ubiquino 1151.224 443 356.308 O76008 A12cd6 Nef-associated factor 1 720.2744 951 424.04 Q9UPY4 K22ef3 nesca protein 425.9149 469 621.9336 L19gh8 neurabin II 1241.544 862 1023.077 Q99742 O07ab8 neuronal PAS domain protein 1 1076.259 405 606.3589 O60448 P20ef3 neuronal thread protein 1831.592 1660 1490.624 Q9UNW9 O05ab8 neuro-oncological ventral antiger 1049.959 1050 1219.792 Q9UGL9 C09gh3 NICE-1 protein 1026.838 1360 381.058 Q9UGL6 M09ef4 NICE-5 protein 912.7542 1390 955.016 Q92982 I09ef7 ninjurin 1 458.23 689 412.0181 Q9BPW8 N19cd3 nipsnap homolog 1 (C. elegans) 829.4266 529 562.9689 Q9NQR4 B13gh4 Nit protein 2 519.1587 868 665.8632 Q9UF10 L08ef2 non-canonical ubquitin conjugati 1336.406 2000 1488.008 Q9Y385 H11ef2 non-canonical ubquitin conjugati 625.6356 808 669.812 Q15233 O02ef1 non-POU domain containing; oct 1083.363 1210 1234.216 Q13137 A03cd6 nuclear domain 10 protein 910.7725 914 944.6079 Q16236 M03cd1 nuclear factor (erythroid-derived 1233.751 1180 1043.638 P08651 B07ef1 nuclear factor I/C (CCAAT-bindin 726.0476 624 659.6305 O95134 P10cd3 nuclear localization signal delete 465.2933 522 536.7333 Q15772 N19ab2 nuclear protein; marker for differ 1473.704 923 1157.202 Q9UHY1 L15cd8 nuclear receptor binding protein 515.949 948 619.7512 Q9UPC9 H23ab2 nuclear receptor coactivator 3 822.7768 1190 932.9058 Q15325 N22cd2 nuclease sensitive element bindi 1644.614 1720 2064.24 O00567 D05cd6 nucleolar protein 5A (56 kD with 659.4335 608 623.2536 Q9NX24 A10gh3 nucleolar protein family A; memb 466.2539 625 594.8443 P06748 K06gh6 nucleophosmin (nucleolar phosp 1605.368 1080 1136.972 P50583 B01ab2 nudix (nucleoside diphosphate li 1590.763 211 251.3768 Q9UHM6 N20gh8 opsin 4 (melanopsin) 1076.73 1200 1643.887 Q9Y218 P22gh1 optineurin 1014.697 1980 912.1917 Q16612 O01cd5 P311 protein 322.7444 349 2231.846 P55771 J21cd7 paired box gene 9 692.506 380 573.135 Q9UKJ1 N21cd8 paired immunoglobulin-like rece 674.1862 450 558.3225 Q15165 P24ab7 paraoxonase 2 338.5244 891 583.7771 Q07002 P06ef5 PCTAIRE protein kinase 3 836.5659 916 632.7298 Q9Y3C6 J07ef2 peptidylprolyl isomerase (cyclop 548.5938 731 526.6097 P30405 F14cd5 peptidylprolyl isomerase F (cyclo 843.1834 925 467.6738 O43924 G24ab8 phosphodiesterase 6D; cGMP-s 373.1208 630 699.1887 P17858 K10ab8 phosphofructokinase; liver 950.5746 525 774.727 Q01813 C17ef1 phosphofructokinase; platelet 573.5211 646 555.9236 O00511 N20cd3 phosphoprotein enriched in astrc 1330.005 1500 2288.098 P11216 B16ab8 phosphorylase; glycogen; brain 516.7884 495 988.163 P00749 P19ef7 plasminogen activator; urokinase 1096.052 3440 1051.513 P13797 C13cd1 plastin 3 (T isoform) 990.1173 804 1393.037 Q15102 E16ab8 platelet-activating factor acetylhy 469.9778 674 468.9765 P01127 A08ef5 platelet-derived growth factor bel 500.6466 674 456.4576 Q15795 C19ef6 pleckstrin homology; Sec7 and 578.295 740 518.8327 O43660 O18ab8 pleiotropic regulator 1 (PRL 1hor 743.7263 933 804.3456 Q15155 G12ef3 pM5 protein 664.2511 423 490.295 Q9H361 L04gh7 poly(A) binding protein; cytoplas 759.4566 491 710.9543 Q15366 A11cd1 poly(rC) binding protein 2 1951.241 1490 2128.585 P19388 B15ab8 polymerase (RNA) II (DNA direct 552.3545 529 698.4965 P52434 F05gh6 polymerase (RNA) II (DNA direct 949.7064 1480 1210.411 P36954 A20cd1 polymerase (RNA) II (DNA direct 1603.557 1820 1413.573 P53803 C17cd1 polymerase (RNA) II (DNA direct 437.9544 893 528.0144 Q9UQQ3 J08cd6 POP4 (processing of precursor; 480.5848 645 551.3661 Q13670 B07ab8 postmeiotic segregation increase 812.7865 779 532.0548 Q9P0J7 L07gh4 potassium channel modulatory fa 1401.591 1720 1192.204 O60925 K02ab8 prefoldin 1 1631.996 1720 1860.632 Q9UHV9 J15ef4 prefoldin 2 514.4897 882 833.1525 Q13519 J07ef6 prepronociceptin 564.2079 464 887.4522 P04156 A13ab8 prion protein (p27-30) Creutzfel 797.9495 631 701.8217 Q9UI73 K03ef8 PRO0246 protein 430.412 535 546.8599 Q9P0T3 D14ef1 proapoptotic caspase adaptor p 1261.463 1650 2553.652 Q02809 P20ab7 procollagen-lysine; 2-oxoglutarat 503.7557 477 1993.232 P07237 G13ab8 procollagen-proline; 2-oxoglutar 633.8309 406 575.6635 P09466 E12ab8 progestagen-associated endome 367.0939 625 708.8717 Q16342 G22ef6 programmed cell death 2 735.0961 759 490.3938 O75340 I02cd8 programmed cell death 6 1055.886 1090 1358.597 P35232 C22ef5 porhibitin 2045.693 1810 1600.236 Q9UQ80 O03cd1 proliferation-associated 2G4; 38 1902.387 1390 2003.135 Q12796 E05ab3 proline rich 2 1927.78 1530 1475.973 Q15188 P20cd2 proline-rich protein BstNI subfa 997.5582 1290 1404.4 P35998 L09ab8 proteasome (prosome; macropali 1010.463 1200 1059.594 P47210 N16cd2 proteasome (prosome; macropali 1037.339 1150 1193 O00495 N03ab8 proteasome (prosome; macropali 1043.875 498 563.7775 O75831 N07ab8 proteasome (prosome; macropali 763.7632 622 506.8297 Q13200 L15ab8 proteasome (prosome; macropali 644.3008 594 331.4288 O43242 L17ab8 proteasome (prosome; macropali 2159.327 1230 1637.67 P55036 N18cd2 proteasome (prosome; macropali 460.8093 724 588.5346 P48556 L21ab8 proteasome (prosome; macropali 1240.243 1030 1685.116 Q92530 G07cd6 proteasome (prosome; macropali 1804.777 1570 1800.731 P28066 J13ab8 proteasome (prosome; macropali 766.589 767 775.2704 O14818 J15ab8 proteasome (prosome; macropali 1242.517 1540 1139.994 P49721 J19ab8 proteasome (prosome; macropali 1832.921 2110 1617.062 P28062 H18ab8 proteasome (prosome; macropali 797.3912 905 505.3638 P28065 B06ef7 proteasome (prosome; macropali 771.1998 1630 1002.72 P10619 A07ab8 protective protein for beta-galac 1539.157 907 980.3046 Q9UNN8 F03cd6 protein C receptor; endothelial (E 892.1589 702 488.5084 Q15084 H02cd5 protein disulfide isomerase-relat 1081.309 407 859.0228 Q9Y2B9 C22cd7 protein kinase (cAMP-dependent 650.9588 1040 754.6101 Q13517 A09ef5 protein kinase C binding protein 380.9448 587 630.5497 P54619 F15ab8 protein kinase; AMP-activated; g 482.8359 572 841.1746 P17612 F13ab8 protein kinase; cAMP-dependent 643.0385 629 901.5293 P09131 F10gh1 Protein P3 529.0069 607 617.0621 O60927 P02gh1 protein phosphatase 1; regulator 1728.646 1760 1404.955 P41236 C08cd1 protein phosphatase 1; regulator 532.1136 621 583.7663 Q15435 D15ab8 protein phosphatase 1; regulator 634.9759 963 753.9046 P05323 E13ef6 protein phosphatase 2 (formerly 1058.276 1120 796.6526 Q15257 G01ef5 protein phosphatase 2A; regulat 925.4458 905 1160.437 P33172 F01ab8 protein phosphatase 4 (formerly 1791.171 1220 1064.665 O00743 F03ab8 protein phosphatase 6; catalytic 998.7 1070 738.4815 P38391 E21cd7 protein translocation complex be 1049.306 1050 1428.451 P78324 M17cd4 protein tyrosine phosphatase; no 639.2381 741 591.4877 Q13332 P21ab8 protein tyrosine phosphatase; re 1882.284 1880 2019.865 Q9HAD6 C08gh6 protocadherin 16 dachsous-like ( 967.2552 906 1070.494 O43445 E11cd5 PRP4 pre-mRNA processing fact 777.1081 549 569.3749 Q9Y6B3 L19ef2 PTD013 protein 652.1251 701 1031.739 Q9HAN1 P19gh6 pumillo homolog 1 (Drosophila) 842.4925 1170 1047.18 Q9NQA4 C23ef4 putative acid-sensing ion channe 742.723 762 678.3813 O43598 J05cd6 putative c-Myc-responsive 473.6498 621 459.383 O43257 M12cd6 putative cyclin G1 interacting pro 1118.374 1190 1238.925 Q9NY06 M07ef4 putative integral membrane trans 966.4384 544 569.8565 P17152 H21cd4 putative receptor protein 399.9305 650 591.3162 Q9Y6I9 B13ef2 putative secreted protein 373.307 485 742.537 P54886 B12ab8 pyrroline-5-carboxylate syntheta 406.7128 302 905.8993 Q13876 B03ef7 quiescin Q6 745.299 585 842.2489 O14679 K24ef5 quinone oxidoreductase homolo 710.5753 1160 651.2257 P53611 N16ab8 Rab geranylgeranyltransferase; 758.1496 727 938.6179 P47224 D06ab8 RAB interacting factor 645.5902 859 577.3956 Q15907 H04cd4 RAB11B; member RAS oncogen 926.8757 1030 1224.758 P51153 D04ab8 RAB13; member RAS oncogene 619.0867 935 1131.86 P35287 J24ef2 RAB14; member RAS oncogene 543.7425 584 586.1635 Q9NP72 P02ef8 RAB18; member RAS oncogene 459.4786 794 634.6616 P11476 H22ab6 RAB1A; member RAS oncogene 1039.455 767 993.586 Q9H0U4 L08gh7 RAB1B; member RAS oncogene 526.9882 691 696.5292 P08886 B22ab8 RAB2; member RAS oncogene f 1483.703 1900 2195.304 O95716 P04cd4 RAB3D; member RAS oncogene 908.9015 638 556.2242 P35239 D02ab8 RAB5B; member RAS oncogene 598.5113 708 393.3892 P20340 C07ef6 RAB6A; member RAS oncogene 503.1507 655 416.7552 P43487 D16ab8 RAN binding protein 1 1438.305 1180 1786.177 Q9UI26 B20ef1 Ran binding protein 11 1505.224 1180 1273.677 P47736 D18ab8 RAP1; GTPase activating protei 875.8692 414 461.3322 Q15382 F17cd2 Ras homolog enriched in brain 2 1435.587 2190 1635.792 P52199 B18ab2 ras homolog gene family; memb 534.6169 1520 399.0517 P35238 B20ab2 ras homolog gene family; memb 1022.646 872 1019.472 Q14644 J08ef7 RAS p21 protein activator (GTPa 615.946 623 627.059 Q15404 A10cd8 Ras suppressor protein 1 1543.953 1920 2317.155 Q13283 H14cd5 Ras-GTPase-activating protein S 846.7267 789 571.1476 Q9NVQ9 M05gh1 Rec8p; a meiotic recombination 1334.371 1200 1325.85 O60895 K17cd6 receptor (calcitonin) activity modi 572.8174 519 899.2606 P35244 I22ef6 replication protein A3 (14 kD) 544.0212 502 924.5385 Q99623 D03cd7 repressor of estrogen receptor a 1139.283 689 1233.151 Q9UMQ4 C01gh1 ret proto-oncogene (multiple end 769.2484 602 803.931 Q9NQC3 M19cd7 reticulon 4 1459.586 586 927.9776 P47804 P03cd1 retinal G protein coupled recepto 403.1219 497 627.4176 Q16576 P07ef6 retinoblastoma binding protein 7 1539.006 1410 798.8744 O95357 D02cd4 retinoic acid induced 3 678.1926 713 206.6352 Q15299 D20ef1 retinoic acid receptor-beta assoc 1060.232 979 1013.444 Q9UMY1 P05ef2 retinoic acid repressible protein 610.5279 726 586.2413 Q13017 M15ef6 Rho GTPase activating protein 5 560.443 807 514.6138 O43182 B24ab2 Rho GTPase activating protein 6 1257.146 806 895.7191 O60274 F04gh6 Rho-specific guanine nucleotide 651.9484 577 366.4761 P07998 P21cd1 ribonuclease; RNase A family; 1 1294.476 3040 1592.811 P04843 B12cd1 ribophorin I 1493.814 1360 2248.214 P04844 B14cd1 ribophorin II 1574.181 1170 1880.047 P26373 D11cd1 ribosomal protein L13 2091.256 1200 1924.546 P40429 H12ef1 ribosomal protein L13a 1928.024 2060 1091.46 P39019 J05cd1 ribosomal protein S19 1794.644 1480 2253.771 P78317 B04cd1 ring finger protein 4 756.2395 661 668.8027 Q99942 F04cd2 ring finger protein 5 1016.837 949 1126.187 O43148 A15cd4 RNA (guanine-7-) methyltransfer 572.6495 730 390.498 O02916 F06ab8 RNA binding motif protein 4 533.7121 628 430.5298 Q9Y580 J10gh6 RNA binding motif protein 7 368.8423 710 558.043 Q14621 H07cd7 RNA binding protein (autoantige 499.5699 737 506.822 Q93062 K17cd7 RNA-binding protein gene with r 845.0994 659 640.4514 Q99497 B15cd7 RNA-binding protein regulatory s 1914.86 1400 2563.974 Q99584 L17cd2 S100 calcium binding protein A1 492.6196 421 675.1457 P23526 A06ef1 S-adenosylhomocysteine hydrol 550.6181 603 478.692 O43865 H21ab2 S-adenosylhomocysteine hydrol 1460.581 526 466.4887 O14826 D02cd5 secretory carrier membrane prot 661.3975 460 481.9262 O75326 L05cd3 sema domain; immunoglobulin d 795.0564 768 943.1132 O43278 I16cd2 serine protease inhibitor; Kunitz 1295.263 1260 641.0775 O00271 C05ef5 serine protease inhibitor; Kunitz 1379.545 1740 876.4128 Q9UEW8 N22ef5 serine threonine kinase 39 (STE 1230.117 1030 841.1872 Q13043 P15cd2 serine/threonine kinase 4 750.7132 838 756.1662 Q9Y282 F01ef2 serologically defined breast canc 1279.414 1160 1907.544 P35542 A02gh1 serum amyloid A4; constitutive 754.5041 1310 811.5701 O75790 I22cd6 seven transmembrane domain pr 761.3872 778 799.0998 Q9P0V3 H17ef3 SH3-domain binding protein 4 1204.005 1710 1539.363 Q99519 C13ab8 sialidase 1 (lysosomal sialidase) 712.4593 680 498.7449 Q92185 J20cd1 sialytransferase 8A (alpha-N-ac 622.4236 478 462.7941 Q9Y6A9 C05ef8 signal peptidase 12 kDa 449.125 742 887.4615 P21378 I04ef3 signal peptidase complex (18 kD) 630.5617 515 732.1592 O15302 P10ab3 signal recognition particle 72 kD 1040.23 818 841.5078 O76094 J02cd2 signal recognition particle 72 kD 1473.56 965 1422.2 Q9UNL2 J10cd2 signal sequence receptor; gamm 1150.724 450 1654.744 P40763 K09ef5 signal transducer and activator o 671.5038 545 348.0347 Q92783 M24cd3 signal transducing adaptor mole 827.9851 1020 725.7017 Q9H723 N01gh5 similar to rat nuclear ubiquitous 749.7661 530 1258.65 O15258 A04cd7 similar to S. cerevisiae RER1 710.8499 635 933.6382 O14834 A11cd7 similar to S. pombe dim1+ 701.2292 753 903.8926 O43617 H05ef3 similar to yeast BET3 (S. cerevis 1759.348 1750 1443.578 Q04837 G11cd2 single-stranded DNA binding pro 1264.277 894 1034.75 P05455 E19gh1 Sjogren syndrome antigen B (aut 850.9691 744 930.6428 P43331 K08cd2 small nuclear ribonucleoprotein 916.3597 1260 1042.335 P09012 M12cd2 small nuclear ribonucleoprotein 548.0261 310 685.6636 P08579 A03cd2 small nuclear ribonucleoprotein 502.6355 570 669.9879 P09234 A05cd2 small nuclear ribonucleoprotein 1054.327 1450 1302.742 P08578 A07cd2 small nuclear ribonucleoprotein 1901.214 1740 1818.557 Q15357 A11cd2 small nuclear ribonucleoprotein 382.4892 734 593.847 P14678 C23cd3 small nuclear ribonucleoprotein 2036.574 1280 1737.398 Q13487 P08cd1 small nuclear RNA activating co 517.5819 684 648.0121 P35326 E17cd3 small proline-rich protein 2A 290.6174 1030 839.3072 P55854 H04cd2 SMT3 suppressor of mif two 3 ho 791.7437 658 962.4453 P14648 P19cd5 SNRPN upstream reading frame 1581.907 2270 1670.964 P55011 L17cd1 solute carrier family 12 (sodium 591.8676 740 517.2382 O95258 P15cd4 solute carrier family 25 (mitochor 476.3075 518 577.8319 O15431 A21ab5 solute carrier family 31 (copper t 1227.872 1010 1769.026 P04920 L04cd1 solute carrier family 4; anion exc 1614.362 1560 1704.134 Q01650 J11ef5 solute carrier family 7 (cationic a 832.6996 632 1032.106 Q07890 H23cd2 son of sevenless homolog 2 (Dro 476.9505 568 680.8529 O60749 A19cd2 sorting nexin 2 364.9343 931 769.5782 O60493 A09cd4 sorting nexin 3 1008.916 1350 1180.469 Q9Y5X3 G06ef4 sorting nexin 5 676.0975 647 688.5568 Q01082 E09cd2 spectrin; beta; non-erythrocytic 1 571.4909 679 387.0403 P52788 M10cd2 spermine synthase 895.1994 854 770.002 P17947 C19cd2 spleen focus forming virus (SFF 1307.418 1150 1646.278 Q14818 D10ef6 splicing factor 1 547.0998 499 782.2929 Q15427 K11cd6 splicing factor 3b; subunit 4; 49k 441.2394 612 540.0723 Q15815 M06cd2 splicing factor; arginine/serine-ri 738.2591 553 551.9082 Q01130 H22cd1 splicing factor; arginine/serine-ri 553.5808 527 488.5465 P23152 H24cd1 splicing factor; arginine/serine-ri 1547.474 1460 1426.273 Q13503 L22cd4 SRB7 suppressor of RNA polym 712.8859 574 725.0591 Q9P2R9 C23ef2 SRp25 nuclear protein 495.796 558 515.095 Q9H6I2 F07gh5 SRY (sex determining region Y)- 774.5162 970 714.8666 Q9BT81 I13gh8 SRY (sex determining region Y)- 497.0608 530 550.1706 O60526 M03cd6 STIP1 homology and U-Box cont 706.6078 538 543.7559 Q9Y6X1 A21ef4 stress-associated endoplasmic 1683.36 1220 2201.647 P31948 M15ef3 stress-induced-phosphoprotein 1 436.1143 549 517.5834 P21912 E09gh1 succinate dehydrogenase compl 701.7228 902 751.7357 O14521 H04cd1 succinate dehydrogenase compl 628.8405 505 672.375 P53597 I09gh1 succinate-CoA ligase; GDP-form 704.4006 491 553.293 O95605 P15cd5 SUMO-1 activating enzyme subu 776.4199 499 433.2742 Q16550 K01cd2 suppressor of Ty 4 homolog 1 (S 813.5735 1440 991.3588 Q15526 K07cd2 surfeit 1 468.3614 522 583.8097 O43539 P02cd1 SWI/SNF related; matrix associa 1047.14 1280 1212.614 Q9UPX1 D23cd7 synaptopodin 683.4973 536 421.1841 O95721 O09cd5 synaptosomal-associated protein 830.7721 1030 686.6755 O43391 H09cd2 syndecan binding protein (synter 625.6962 640 379.1899 Q15833 J04cd2 syntaxin binding protein 2 661.0175 556 840.6951 Q92804 O20cd3 TAF15 RNA polymerase II; TAT 873.5584 605 1063.778 Q9Y490 B04cd2 talin 1 1342.238 1170 2365.625 O94797 H20ef7 Tara-like protein 899.0807 448 496.1404 Q13311 C05cd6 Tax1 (human T-cell leukemia vir 899.9979 1190 926.2314 Q16650 F08cd6 T-box; brain; 1 1407.309 1750 1777.889 P51864 O04ef7 teratocarcinoma-derived growth 2037.212 1590 1447.46 P55061 O19cd2 testis enhanced gene transcript ( 1540.968 1330 1972.323 Q15569 P21cd2 testis-specific kinase 1 837.6269 796 708.1178 O60636 F08cd5 tetraspan 2 468.1664 702 375.3225 O60637 F06cd5 tetraspan 3 1025.362 742 545.9662 O95857 F13ef3 tetraspan NET-6 protein 702.1579 676 359.1921 Q99614 M03cd3 tetratricopeptide repeat domain 1 706.3536 891 635.5379 Q13118 L05cd2 TGFB inducible early growth res 445.9691 601 679.2931 Q15583 A16cd2 TGFB-induced factor (TALE fami 885.9 1290 1140.439 Q9H3N1 N03gh7 thioredoxin domain-containing 409.6333 426 686.7997 O43396 O17cd5 thioredoxin-like; 32 kD 1821.595 1710 1548.596 P04216 B02cd2 Thy-1 cell surface antigen 169.8064 298 4157.367 P12956 K10ef6 thyroid autoantigen 70 kD (Ku an 1172.56 1490 1395.803 P16035 P11ef7 tissue inhibitor of metalloprotein 360.2533 354 913.1351 Q9H2X8 I08gh8 TLH29 protein precursor 710.2447 1000 1386.102 Q13077 L11cd2 TNF receptor-associated factor 1 1265.054 1270 756.401 Q9NZ34 P08gh4 TPA regulated locus 1074.319 1090 1284.44 Q15369 D18ef6 transcription elongation factor B 771.5598 1100 693.1767 Q15906 P11ef6 transcription factor-like 1 436.5561 510 878.9083 P50616 H08cd5 transducer of ERBB2; 1 888.8059 874 518.1816 Q13595 N04ef7 transformer-2 alpha (htra-2 alpha 247.4437 612 698.379 P37802 F05cd3 transgelin 2 1986.716 2240 1173.434 Q9Y5Z9 D01cd8 transitional epithelia response pr 1324.284 875 1126.793 Q99595 K10cd6 translocase of inner mitochondri 450.6578 665 448.5161 O60830 A09cd6 translocase of inner mitochondri 1646.564 1590 1992.925 O14925 I24cd6 translocase of inner mitochondri 745.8102 813 653.4301 Q9Y5J9 E08cd8 translocase of inner mitochondri 1641.377 1550 1653.524 Q15629 G18ef3 translocating chain-associating n 1003.031 1060 624.4499 Q99442 C10cd2 translocation protein 1 526.8783 772 1065.397 Q99805 A18cd5 transmembrane 9 superfamily m 1023.368 1260 957.2801 Q9Y2B0 C20ef3 transmembrane protein 4 681.3857 1320 985.8397 P49755 J05ef4 transmembrane trafficking protei 1311.203 469 700.7243 F03gh4 transmembrane; prostate androg 1287.98 841 662.4165 Q03519 B07cd1 transporter 2; ATP-binding casse 851.2148 573 680.8519 Q9NWF9 P02gh2 TRIAD3 protein 665.9772 444 688.6646 Q15656 O07ef7 TRK-fused gene 1878.254 1640 1858.307 Q92734 J17cd7 TRK-fused gene 1450.307 1810 1609.067 Q12815 A21ef7 trophinin associated protein (last 821.5601 1100 722.8644 P09493 O02cd1 tropomyosin 1 (alpha) 988.1694 429 1004.982 P49411 M11cd3 Tu translation elongation factor; 525.8572 555 476.4592 P05217 F03gh6 tubulin; beta; 2 1203.686 705 920.1831 P23258 K03cd3 tubulin; gamma 1 1733.971 1220 2149.365 Q9UBN6 A16ef6 tumor necrosis factor receptor su 470.7412 751 531.524 Q13829 L22ef4 tumor necrosis factor; alpha-indu 849.276 792 552.7776 O00496 K21cd3 tumor suppressing subtransferab 628.3509 554 800.8751 Q99816 G04cd4 tumor susceptibility gene 101 723.8133 766 627.1295 P16422 C03ab7 tumor-associated calcium signal 1448.512 791 373.663 Q9NP84 K03ef2 type I transmembrane protein Fn 691.89 498 560.2824 Q9UJ47 O09cd8 type I transmembrane receptor ( 792.9873 819 809.9056 P31946 K21ef6 tyrosine 3-monooxygenase/tryp 1220.989 955 724.9898 P35214 J19ef4 tyrosine 3-monooxygenase/tryp 881.0131 989 682.5327 P27348 G15cd7 tyrosine 3-monooxygenase/tryp 2196.334 1540 1104.855 O60704 J01cd3 tyrosylprotein sulfotransferase 2 658.3761 299 686.1339 Q9Y4Z0 G09cd8 U6 snRNA-associated Sm-like pr 837.5087 689 914.9547 P14927 G06cd4 ubiquinol-cytochrome c reductas 995.1237 817 954.3085 Q9UI02 P18ef7 ubiquinol-cytochrome c reductas 953.6884 1460 1546.568 P31930 A22cd3 ubiquinol-cytochrome c reductas 846.6396 849 686.9864 P22695 A24cd3 ubiquinol-cytochrome c reductas 468.5936 636 581.791 P07919 E08cd4 ubiquinol-cytochrome c reductas 1328.532 1810 1005.378 P47985 E06cd4 ubiquinol-cytochrome c reductas 1519.763 1270 1127.575 Q9NZ09 N17ef1 ubiquitin associated protein 1588.177 1820 1392.592 Q9UNP0 F09gh6 ubiquitin specific protease 15 525.3364 492 597.7817 Q9UHP3 L21cd8 ubiquitin specific protease 25 554.0657 724 561.5817 P22314 O07cd3 ubiquitin-activating enzyme E1 ( 1857.238 1640 1863.316 Q13404 O23cd3 ubiquitin-conjugating enzyme E2 1073.414 1210 1128.962 P51669 D05cd4 ubiquitin-conjugating enzyme E2 1266.25 1300 1173.73 P47986 O11cd3 ubiquitin-conjugating enzyme E2 616.3689 520 567.7317 O14933 H14cd4 ubiquitin-conjugating enzyme E2 717.4244 893 596.6415 Q16781 D07cd4 ubiquitin-conjugating enzyme E2 923.6537 816 533.7389 Q93068 A02cd3 ubiquitin-like 1 (sentrin) 1376.087 1530 1294.307 Q15386 I10gh1 ubiquitin-protein isopeptide ligas 531.8659 630 628.2454 Q9UBK9 I15cd4 ubiquitously-expressed transcrip 936.2619 1060 1384.764 O60512 E11ab3 UDP-Gal: betaGlcNAc beta 1; 4- 436.7634 610 542.39 P78383 P20cd5 UDP-galactose transporter relat 1570.135 1700 2180.117 Q16851 I24cd4 UDP-glucose pyrophosphorylase 1324.08 1260 1318.78 Q9NZ45 L02gh3 uncharacterized hematopoietic s 652.0685 670 696.5692 Q9NZ32 L20gh4 uncharacterized hypothalamus p 1035.575 1250 1354.231 Q9NZ29 L16gh4 uncharacterized hypothalamus p 659.53 992 1118.776 Q15853 C02cd3 upstream transcription factor 2; c 601.6839 635 698.0128 Q92528 D02ef7 uridine monophosphate kinase 560.3976 685 623.5243 P15692 M04ef7 vascular endothelial growth facto 460.9257 539 857.3853 P50552 C08cd3 vasodilator-stimulated phosphop 468.4573 648 392.5569 O60763 H16cd3 vesicle docking protein p115 639.538 543 745.4806 Q15836 A15ef5 vesicle-associated membrane p 804.2648 1370 1060.211 Q9UEU0 O22cd6 vesicle-associated soluble NSF 468.6024 697 698.3534 P14921 E24ef5 v-ets erythroblastosis virus E26 913.893 765 291.1538 P18206 C14cd3 vinculin 580.3315 857 865.7505 P00540 G08ef5 v-mos Moloney murine sarcoma 1115.145 728 663.6747 P01106 E18ef5 v-myc myelocytomatosis viral on 537.8131 601 405.1047 P21796 C16cd3 voltage-dependent anion channe 483.8969 510 584.201 Q15765 C12cd3 von Hippel-Lindau binding prote 689.743 705 891.2621 P10398 D01ab4 v-raf murine sarcoma 3611 viral 1061.812 639 532.2153 P11233 A19ef6 v-ral simian leukemia viral oncog 848.7099 1060 1081.428 Q9Y6W5 A22gh1 WAS protein family; member 2 1283.077 1630 1493.145 Q9UPY6 L06cd6 WAS protein family; member 3 1503.584 1210 2151.643 O75083 D15cd5 WD repeat domain 1 892.4425 977 963.3448 O76071 A24cd5 WD40 protein Clao1 609.8821 898 730.5311 Q9HCN4 H11gh6 XPA binding protein 1; putative 1199.21 1070 507.3277 Q9UM05 N17ef3 yeast Sec31p homolog 1887.447 1590 1542.778 Q9UQR1 P06gh1 zinc finger protein 148 (pHZ-52) 513.8639 737 563.7625 Q14119 G21ef5 zinc finger protein 161 1199.558 1760 1197.34 Q9NW07 F06gh2 zinc finger protein 358 402.8342 575 684.7069 P20694 D04ef6 zinc finger protein 9 (a cellular re 1042.65 1010 856.5924 SwissProt allMean ratioItoA rationIntto classID classsName P04270 2637.676 2.31E+00 −6.57E−01 7 Equal A/Int; Up Islets O95996 5161.464 1.49E+00 9.36E−01 7 Equal A/Int; Up Islets Q14697 477.0123 1.34E+00 1.92E−01 7 Equal A/Int; Up Islets P14209 711.8924 1.67E+00 3.80E−01 7 Equal A/Int; Up Islets P30530 412.2115 1.01E+00 −1.29E−01 7 Equal A/Int; Up Islets O43770 1085.931 1.10E+00 5.87E−01 7 Equal A/Int; Up Islets O43852 2269.921 2.56E+00 6.84E−01 7 Equal A/Int; Up Islets O75718 592.2327 1.34E+00 −7.52E−01 7 Equal A/Int; Up Islets Q9Y3C0 229.7237 1.20E+00 7.36E−01 7 Equal A/Int; Up Islets P78369 1505.471 1.14E+00 −6.65E−01 7 Equal A/Int; Up Islets P08572 2389.488 2.05E+00 2.60E−01 7 Equal A/Int; Up Islets P11802 1411.839 1.36E+00 9.79E−02 7 Equal A/Int; Up Islets Q16555 399.8267 3.01E+00 5.14E−01 7 Equal A/Int; Up Islets P33316 318.7836 1.61E+00 4.23E−01 7 Equal A/Int; Up Islets P07992 561.6388 1.33E+00 1.97E−01 7 Equal A/Int; Up Islets O75636 2139.448 2.00E+00 −9.87E−02 7 Equal A/Int; Up Islets Q9UBA6 812.6378 2.01E+00 6.41E−01 7 Equal A/Int; Up Islets Q9Y5P5 261.0679 1.27E+00 2.10E−01 7 Equal A/Int; Up Islets O75293 261.3841 9.92E−01 6.35E−02 7 Equal A/Int; Up Islets P50152 283.8702 1.28E+00 −4.53E−01 7 Equal A/Int; Up Islets Q9NX09 545.0622 1.57E+00 −4.61E−01 7 Equal A/Int; Up Islets P05204 3082.818 1.55E+00 −8.84E−01 7 Equal A/Int; Up Islets Q9P0P2 462.1583 1.07E+00 2.14E−01 7 Equal A/Int; Up Islets Q9NWF8 262.6222 1.12E+00 4.88E−01 7 Equal A/Int; Up Islets Q9NWV4 328.2481 1.13E+00 3.37E−01 7 Equal A/Int; Up Islets Q9P0S8 216.4274 1.11E+00 9.72E−02 7 Equal A/Int; Up Islets Q9BWS9 261.7132 1.12E+00 −2.90E−01 7 Equal A/Int; Up Islets Q9BSK0 319.1224 2.13E+00 −4.25E−01 7 Equal A/Int; Up Islets Q9Y6M1 232.2937 1.59E+00 1.79E−01 7 Equal A/Int; Up Islets Q9NQX7 687.2575 1.20E+00 8.97E−03 7 Equal A/Int; Up Islets P08648 262.0713 1.38E+00 −5.65E−01 7 Equal A/Int; Up Islets O00410 384.2402 9.47E−01 −7.35E−01 7 Equal A/Int; Up Islets P07195 2599.05 2.48E+00 2.57E−01 7 Equal A/Int; Up Islets P09382 44205.77 2.03E+00 8.83E−01 7 Equal A/Int; Up Islets O75427 316.5457 1.63E+00 4.03E−01 7 Equal A/Int; Up Islets Q16553 619.3701 1.14E+00 2.13E−01 7 Equal A/Int; Up Islets O75900 510.1038 1.16E+00 −3.58E−01 7 Equal A/Int; Up Islets Q9UNF1 357.6132 1.77E+00 1.77E−01 7 Equal A/Int; Up Islets P13995 435.6746 1.24E+00 −5.09E−01 7 Equal A/Int; Up Islets O00265 267.156 9.93E−01 3.03E−01 7 Equal A/Int; Up Islets P27361 486.849 1.01E+00 9.38E−02 7 Equal A/Int; Up Islets P24844 11793.09 2.04E+00 4.29E−01 7 Equal A/Int; Up Islets Q9NVD4 237.1908 1.35E+00 1.26E−01 7 Equal A/Int; Up Islets Q9Y617 553.0005 2.87E+00 5.58E−01 7 Equal A/Int; Up Islets O95356 901.8229 3.26E+00 −3.05E−01 7 Equal A/Int; Up Islets Q9Y5X6 226.0168 1.11E+00 −2.58E−01 7 Equal A/Int; Up Islets Q15113 1176.046 2.40E+00 −3.08E−01 7 Equal A/Int; Up Islets O15460 483.9569 1.53E+00 7.25E−01 7 Equal A/Int; Up Islets O43556 245.5263 1.02E+00 3.13E−01 7 Equal A/Int; Up Islets P50454 1680.942 3.59E+00 8.53E−01 7 Equal A/Int; Up Islets Q92853 664.6951 1.17E+00 3.15E−01 7 Equal A/Int; Up Islets Q16658 738.014 2.49E+00 8.66E−01 7 Equal A/Int; Up Islets Q9Y4Y8 361.3772 1.09E+00 1.12E−01 7 Equal A/Int; Up Islets Q9BVH9 968.9954 1.87E+00 −1.18E−01 7 Equal A/Int; Up Islets Q9HBB0 603.8101 1.76E+00 1.90E−01 7 Equal A/Int; Up Islets P01033 5256.861 3.40E+00 2.83E−01 7 Equal A/Int; Up Islets Q15582 3939.09 2.81E+00 7.51E−01 7 Equal A/Int; Up Islets Q01995 8573.074 2.49E+00 2.29E−01 7 Equal A/Int; Up Islets Q13641 768.6158 1.55E+00 −1.70E−01 7 Equal A/Int; Up Islets P06468 4710.469 5.28E+00 7.96E−01 7 Equal A/Int; Up Islets P51784 280.9819 1.64E+00 2.94E−01 7 Equal A/Int; Up Islets P03996 14717.63 6.66E+00 2.23E+00 9 Increasing A/Int/I P08123 5109.251 6.29E+00 1.63E+00 9 Increasing A/Int/I P24821 1215.165 2.74E+00 1.37E+00 9 Increasing A/Int/I Q9NVA2 1568.848 3.21E+00 1.20E+00 9 Increasing A/Int/I P40261 3016.993 2.42E+00 1.12E+00 9 Increasing A/Int/I Q15063 3133.301 4.91E+00 1.52E+00 9 Increasing A/Int/I P09486 22333.48 7.30E+00 2.77E+00 9 Increasing A/Int/I P35625 3637.823 5.54E+00 1.52E+00 9 Increasing A/Int/I Q9H2L5 400.4602 −1.19E+00 9.15E−00 19 Int> (A; I) P15121 3354.494 −3.51E−03 1.20E+00 19 Int> (A; I) P08582 324.9781 −1.89E+00 9.92E−00 19 Int> (A; I) P20292 330.0345 1.02E+00 2.78E+00 19 Int> (A; I) O15342 9572.914 2.31E−02 1.44E+00 19 Int> (A; I) Q9BXJ0 228.0109 −2.26E−01 9.55E−00 19 Int> (A; I) Q9NRJ3 948.0274 1.61E+00 2.87E+00 19 Int> (A; I) P05305 1026.992 −1.10E+00 1.06E+00 19 Int> (A; I) P09341 2236.622 1.09E−01 2.35E+00 19 Int> (A; I) Q92730 1318.381 −2.69E−01 2.08E+00 19 Int> (A; I) Q9H5K0 192.6442 −2.14E−01 9.71E−01 19 Int> (A; I) P18564 650.9277 −1.21E+00 1.13E+00 19 Int> (A; I) P14316 326.8164 1.90E−02 9.04E−01 19 Int> (A; I) P40305 367.2688 8.96E−01 2.71E+00 19 Int> (A; I) P05161 537.4035 1.11E−01 1.70E+00 19 Int> (A; I) P42701 8218.994 1.20E−01 4.17E+00 19 Int> (A; I) P09237 38905.32 1.05E+00 3.18E+00 19 Int> (A; I) P16860 6171.6 −1.78E+00 1.57E+00 19 Int> (A; I) P21359 193.3208 2.27E−01 1.14E+00 19 Int> (A; I) P02775 567.1992 2.96E+00 5.37E+00 19 Int> (A; I) Q9UDQ9 479.5908 9.74E−01 3.15E+00 19 Int> (A; I) O75635 1483.169 4.88E−01 4.06E+00 19 Int> (A; I) P02735 6295.724 9.46E−01 5.13E+00 19 Int> (A; I) O60635 447.5729 −8.58E−01 1.39E+00 19 Int> (A; I) P50591 854.3061 −1.73E−01 1.53E+00 19 Int> (A; I) Q03169 650.583 −1.67E−01 1.78E+00 19 Int> (A; I) Q9C075 1818.182 −1.08E+00 2.31E+00 19 Int> (A; I) P02248 369.9913 −1.33E+00 2.52E+00 19 Int> (A; I) O95497 887.0948 7.24E−01 2.57E+00 19 Int> (A; I) Q14202 496.3668 3.13E−01 2.38E+00 19 Int> (A; I) P15514 191.2981 −6.52E−01 1.97E+00 18 Off A/I; On Int Q9BZL9 140.8098 −5.80E−01 7.42E−01 18 Off A/I; On Int P30991 148.3131 9.01E−01 2.02E+00 18 Off A/I; On Int P29400 189.6904 1.40E+00 2.81E+00 18 Off A/I; On Int Q9UK22 141.6466 4.59E−01 1.31E+00 18 Off A/I; On Int Q16769 132.7502 3.31E−01 1.12E+00 18 Off A/I; On Int P02261 151.868 9.52E−01 2.01E+00 18 Off A/I; On Int P20769 126.7136 1.87E−02 8.00E−01 18 Off A/I; On Int P52945 170.7555 2.12E−01 2.24E+00 18 Off A/I; On Int Q14496 161.3017 −1.45E−02 1.53E+00 18 Off A/I; On Int P01583 181.5566 −6.34E−01 1.86E+00 18 Off A/I; On Int P01584 216.8707 2.75E−02 1.83E+00 18 Off A/I; On Int Q9GZM1 183.8736 −7.99E−03 1.77E+00 18 Off A/I; On Int P25105 177.9689 −2.76E−01 1.87E+00 18 Off A/I; On Int P58294 152.9437 7.82E−01 1.59E+00 18 Off A/I; On Int P23471 175.0253 1.30E−01 2.02E+00 18 Off A/I; On Int O88386 196.7342 −8.54E−01 1.69E+00 18 Off A/I; On Int P10826 143.3844 8.31E−01 1.83E+00 18 Off A/I; On Int O95786 147.8829 −3.38E−01 1.10E+00 18 Off A/I; On Int P02778 189.6022 4.05E−01 2.68E+00 18 Off A/I; On Int P80162 164.6594 1.26E+00 2.52E+00 18 Off A/I; On Int P43005 133.1898 1.58E−01 9.32E−01 18 Off A/I; On Int P01375 200.0804 −8.84E−01 1.48E+00 18 Off A/I; On Int Q16890 130.885 −7.92E−02 8.84E−01 18 Off A/I; On Int Q9H949 136.5769 −4.92E−01 9.64E−01 18 Off A/I; On Int Q9H4G4 281.2148 2.59E+00 1.33E+00 8 Off Acinar; Increasing Int/I Q14040 1657.194 6.95E+00 2.45E+00 8 Off Acinar; Increasing Int/I P12110 1362.487 5.45E+00 8.97E−01 8 Off Acinar; Increasing Int/I P02751 1442.812 9.88E+00 5.10E+00 8 Off Acinar; Increasing Int/I P14652 1308.575 5.83E+00 2.21E+00 8 Off Acinar; Increasing Int/I P08476 412.2794 3.73E+00 2.30E+00 8 Off Acinar; Increasing Int/I P17936 563.1937 5.09E+00 3.19E+00 8 Off Acinar; Increasing Int/I Q9Y4K0 953.7036 5.06E+00 1.77E+00 8 Off Acinar; Increasing Int/I P03956 299.8442 2.47E+00 9.53E−01 8 Off Acinar; Increasing Int/I P39900 539.7471 6.06E+00 4.39E+00 8 Off Acinar; Increasing Int/I P55001 1309.293 5.06E+00 2.40E+00 8 Off Acinar; Increasing Int/I Q9NYR0 296.0285 4.24E+00 2.50E+00 8 Off Acinar; Increasing Int/I O43623 1139.155 4.97E+00 1.59E+00 8 Off Acinar; Increasing Int/I P09936 596.7714 4.98E+00 2.18E+00 8 Off Acinar; Increasing Int/I Q02952 232.3779 1.14E+00 1.81E+00 4 Off Acinar; On Int = I Q99541 132.005 1.12E+00 1.44E+00 4 Off Acinar; On Int = I P54284 195.985 1.26E+00 1.09E+00 4 Off Acinar; On Int = I Q13269 170.529 1.11E+00 9.40E−01 4 Off Acinar; On Int = I Q9NPF2 209.7612 1.18E+00 5.24E−01 4 Off Acinar; On Int = I Q9H7A5 161.8637 1.08E+00 8.58E−01 4 Off Acinar; On Int = I Q9H9Q2 128.7341 1.09E+00 4.14E−01 4 Off Acinar; On Int = I P42771 290.1928 3.04E+00 3.44E+00 4 Off Acinar; On Int = I Q14650 242.2271 1.28E+00 1.04E+00 4 Off Acinar; On Int = I Q96IK6 113.265 −6.73E−01 −4.89E−01 4 Off Acinar; On Int = I P12034 212.2747 2.40E+00 2.10E+00 4 Off Acinar; On Int = I Q93079 281.3281 9.07E−01 1.56E+00 4 Off Acinar; On Int = I Q9P016 290.4476 1.69E+00 1.50E+00 4 Off Acinar; On Int = I Q9HBI5 233.835 1.41E+00 1.24E+00 4 Off Acinar; On Int = I Q9BY45 121.5622 1.17E+00 4.74E−01 4 Off Acinar; On Int = I P08397 196.1361 9.07E−01 4.38E−01 4 Off Acinar; On Int = I Q9BUV0 129.3473 1.29E+00 1.15E+00 4 Off Acinar; On Int = I Q9H9A2 120.7311 1.04E+00 4.16E−01 4 Off Acinar; On Int = I Q9NUV6 134.1021 6.44E−01 1.03E+00 4 Off Acinar; On Int = I Q9NXF7 126.7851 1.36E+00 1.11E+00 4 Off Acinar; On Int = I Q9H6V0 232.5844 1.47E+00 1.15E+00 4 Off Acinar; On Int = I Q9BUW5 151.3887 1.34E+00 1.08E+00 4 Off Acinar; On Int = I Q9H765 177.6046 9.58E−01 1.05E+00 4 Off Acinar; On Int = I Q14157 129.9305 6.35E−01 6.27E−01 4 Off Acinar; On Int = I Q9Y2D8 176.1358 1.30E+00 1.50E+00 4 Off Acinar; On Int = I Q9H6Z3 185.578 1.10E+00 8.85E−01 4 Off Acinar; On Int = I Q99748 173.2957 9.94E−01 2.74E−01 4 Off Acinar; On Int = I Q9NVD7 151.1753 1.48E+00 7.62E−01 4 Off Acinar; On Int = I O43175 136.6151 9.61E−01 2.64E−01 4 Off Acinar; On Int = I Q9Y253 122.2465 5.44E−01 −1.06E−01 4 Off Acinar; On Int = I P24158 180.0275 9.80E−01 1.67E+00 4 Off Acinar; On Int = I Q9U8K7 204.6287 1.50E+00 7.72E−01 4 Off Acinar; On Int = I Q13636 121.5169 1.15E+00 6.30E−01 4 Off Acinar; On Int = I Q9UIC2 148.7422 1.27E+00 1.08E+00 4 Off Acinar; On Int = I Q9NVQ7 129.1434 9.72E−01 7.89E−01 4 Off Acinar; On Int = I O75368 167.1823 1.08E+00 1.19E+00 4 Off Acinar; On Int = I O95863 122.817 1.04E+00 8.06E−01 4 Off Acinar; On Int = I Q9UL01 124.5829 1.03E+00 3.51E−01 4 Off Acinar; On Int = I Q16226 364.6675 2.25E+00 2.03E+00 4 Off Acinar; On Int = I P07996 127.0819 1.05E+00 8.15E−01 4 Off Acinar; On Int = I Q99081 182.9347 1.19E+00 6.86E−01 4 Off Acinar; On Int = I O95922 190.8311 1.80E+00 1.75E+00 4 Off Acinar; On Int = I P15036 115.8531 −8.43E−01 −3.94E−01 4 Off Acinar; On Int = I O95337 172.7489 2.03E+00 1.24E+00 4 Off Acinar; On Int = I Q9H1B5 120.5878 1.09E+00 3.68E−01 4 Off Acinar; On Int = I P55263 637.198 −1.57E+00 −3.08E−01 15 On A/Int; Down I P51648 1284.046 −1.95E+00 −4.93E−01 15 On A/Int; Down I P50995 3511.843 −1.46E+00 −3.36E−01 15 On A/Int; Down I P12429 7424.351 −2.50E+00 1.59E−01 15 On A/Int; Down I P05026 3744.962 −1.00E+00 4.16E−01 15 On A/Int; Down I P00751 2206.568 −1.34E+00 −2.81E−01 15 On A/Int; Down I Q9HA23 400.5912 −1.32E+00 1.36E−01 15 On A/Int; Down I Q16170 807.5766 −2.21E+00 3.15E−01 15 On A/Int; Down I P25774 620.9386 −1.91E+00 −1.45E−01 15 On A/Int; Down I P21926 2115.74 −1.27E+00 8.00E−01 15 On A/Int; Down I Q9H2A7 576.1228 −1.46E+00 3.71E−01 15 On A/Int; Down I O14493 1732.749 −1.26E+00 3.70E−01 15 On A/Int; Down I P12277 394.4895 −9.53E−01 7.22E−01 15 On A/Int; Down I Q9NYS7 397.3278 −1.50E+00 −6.35E−01 15 On A/Int; Down I P53355 1048.818 −1.25E+00 −7.03E−02 15 On A/Int; Down I O15205 8102.423 −1.75E+00 1.00E+00 15 On A/Int; Down I Q9UFZ2 900.9109 −2.08E+00 −3.18E−01 15 On A/Int; Down I P28562 1502.864 −1.46E+00 −3.09E−01 15 On A/Int; Down I Q16690 315.2743 −1.65E+00 −6.70E−01 15 On A/Int; Down I Q9UJW0 592.1023 −1.21E+00 −2.34E−01 15 On A/Int; Down I 265.0097 −3.52E−01 6.91E−01 15 On A/Int; Down I P00533 259.7582 −5.29E−01 3.42E−01 15 On A/Int; Down I Q13113 10494.6 −2.33E+00 2.20E−01 15 On A/Int; Down I P28161 642.7437 −2.23E+00 −5.63E−01 15 On A/Int; Down I Q03013 336.469 −6.60E−01 4.81E−01 15 On A/Int; Down I P52594 386.6697 −7.98E−01 9.00E−02 15 On A/Int; Down I Q9NWT9 729.2943 −1.53E+00 −4.89E−01 15 On A/Int; Down I Q9BZR4 584.0643 −2.22E+00 1.74E−01 15 On A/Int; Down I Q9BW25 291.8079 −1.07E+00 3.76E−01 15 On A/Int; Down I P16144 440.0464 −1.64E+00 4.54E−01 15 On A/Int; Down I P10145 7330.866 −1.95E+00 9.47E−01 15 On A/Int; Down I Q05084 465.8994 −1.52E+00 −3.05E−02 15 On A/Int; Down I Q9Y484 1429.625 −5.08E−01 5.93E−01 15 On A/Int; Down I P14923 1831.613 −1.11E+00 4.07E−01 15 On A/Int; Down I P05783 10707.79 −2.91E+00 −4.70E−01 15 On A/Int; Down I P08727 2484.93 −2.67E+00 −5.25E−01 15 On A/Int; Down I P08729 8203.912 −2.62E+00 −6.19E−02 15 On A/Int; Down I P05787 6867.677 −2.70E+00 −4.86E−01 15 On A/Int; Down I O14782 420.177 −5.97E−01 8.31E−01 15 On A/Int; Down I O00515 2140.683 −2.11E+00 −8.08E−01 15 On A/Int; Down I P80188 4989.308 −2.98E+00 7.93E−01 15 On A/Int; Down I Q9UQ53 938.2331 −1.90E+00 −6.75E−01 15 On A/Int; Down I P80294 300.7815 −6.50E−01 1.57E−01 15 On A/Int; Down I O75394 433.794 −1.05E+00 5.49E−01 15 On A/Int; Down I Q9Y376 939.6431 −6.45E−01 7.11E−01 15 On A/Int; Down I P15941 1357.116 −2.26E+00 −8.95E−01 15 On A/Int; Down I Q16301 1844.855 −2.16E+00 7.14E−02 15 On A/Int; Down I Q99836 871.4196 −1.40E+00 3.15E−02 15 On A/Int; Down I P24001 44684.13 −1.86E+00 5.34E−01 15 On A/Int; Down I Q9C002 10242.28 −9.60E−1 1.04E+00 15 On A/Int; Down I P25963 937.0159 −6.33E−01 4.32E−01 15 On A/Int; Down I P00491 523.7383 −1.71E+00 −7.13E−01 15 On A/Int; Down I P49763 6646.258 −1.70E+00 1.17E+00 15 On A/Int; Down I Q9Y342 742.036 −1.65E+00 6.10E−02 15 On A/Int; Down I P43490 1546.408 −1.80E+00 −3.90E−01 15 On A/Int; Down I Q99988 1694.813 −1.11E+00 9.96E−01 15 On A/Int; Down I Q9UJY1 1485.828 −1.75E+00 1.77E−01 15 On A/Int; Down I Q9H1C7 9771.26 −1.90E+00 3.69E−01 15 On A/Int; Down I P51149 3646.784 −5.94E−01 6.18E−1 15 On A/Int; Down I P51151 1393.904 −1.38E+00 −2.55E−01 15 On A/Int; Down I P15153 338.0922 −8.47E−01 1.26E−01 15 On A/Int; Down I P52566 708.6827 −1.49E+00 −3.24E−01 15 On A/Int; Down I P01011 31439.89 −1.99E+00 1.11E−01 15 On A/Int; Down I P05120 21999.69 −3.11E+00 6.16E−01 15 On A/Int; Down I O14508 1139.68 −1.85E+00 −2.42E−02 15 On A/Int; Down I Q9Y6N5 659.5107 −1.54E+00 7.99E−02 15 On A/Int; Down I O00161 1034.031 −6.50E−01 3.11E−01 15 On A/Int; Down I P31431 2026.067 −1.25E+00 5.46E−01 15 On A/Int; Down I O15533 299.8834 −9.48E−01 4.38E−01 15 On A/Int; Down I P17987 317.0491 −1.65E+00 −7.35E−01 15 On A/Int; Down I O14746 262.9869 −8.05E−01 4.92E−01 15 On A/Int; Down I P30408 13372.16 −1.46E+00 6.34E−02 15 On A/Int; Down I Q9HCN3 806.2983 −1.04E+00 9.01E−02 15 On A/Int; Down I Q16149 813.3307 −8.42E−01 3.47E−01 15 On A/Int; Down I Q9Y2A9 454.8446 −2.33E+00 −8.29E−01 15 On A/Int; Down I O60625 1914.133 −2.09E+00 1.10E−01 15 On A/Int; Down I P07948 375.1466 −1.59E+00 −2.12E−01 15 On A/Int; Down I Q9P2N4 153.1495 −1.13E+00 5.06E−01 14 On A/Int; Off I P47895 1254.954 −3.09E+00 9.27E−01 14 On A/Int; Off I P04233 163.6002 −1.40E+00 −3.96E−01 14 On A/Int; Off I Q9NZ31 285.9642 −1.33E+00 1.18E−01 14 On A/Int; Off I O96002 302.4558 −1.62E+00 −9.81E−02 14 On A/Int; Off I O94907 145.044 −8.30E−01 4.14E−01 14 On A/Int; Off I Q92796 133.5184 −9.32E−01 −7.56E−02 14 On A/Int; Off I Q13115 469.8392 −1.87E+00 4.52E−01 14 On A/Int; Off I P29317 209.5143 −1.70E+00 5.78E−02 14 On A/Int; Off I P29323 191.9946 −1.86E+00 −2.11E−01 14 On A/Int; Off I Q9UKF9 430.6372 −2.56E+00 −3.92E−02 14 On A/Int; Off I Q9NPD3 207.9117 −2.46E+00 1.36E−01 14 On A/Int; Off I O43524 177.9385 −1.35E+00 −6.35E−01 14 On A/Int; Off I P21217 168.8097 −1.65E+00 4.40E−01 14 On A/Int; Off I O75205 364.8596 −2.77E+00 −7.03E−01 14 On A/Int; Off I O75712 260.8655 −6.93E−01 7.72E−01 14 On A/Int; Off I Q92908 195.3976 −1.65E+00 −5.55E−01 14 On A/Int; Off I O95210 228.6851 −1.56E+00 −4.60E−01 14 On A/Int; Off I O95395 205.5863 −2.70E+00 −1.21E−01 14 On A/Int; Off I P48506 225.879 −1.15E+00 −2.97E−01 14 On A/Int; Off I Q9UI98 266.8154 −1.74E+00 −8.96E−02 14 On A/Int; Off I Q9H6D8 421.5312 −2.09E+00 1.32E−01 14 On A/Int; Off I P05362 301.0074 −2.60E+00 4.56E−02 14 On A/Int; Off I Q07627 210.3957 −2.84E+00 6.93E−02 14 On A/Int; Off I Q9BYQ7 398.2261 −2.35E+00 2.93E−01 14 On A/Int; Off I O75071 166.3595 −1.39E+00 −5.24E−01 14 On A/Int; Off I Q9UPQ2 236.4102 −7.28E−01 6.34E−01 14 On A/Int; Off I O43896 134.4385 −1.12E+00 9.16E−02 14 On A/Int; Off I Q13887 322.6178 −2.34E+00 −3.93E−01 14 On A/Int; Off I O00312 128.2701 −7.73E−01 2.20E−02 14 On A/Int; Off I O15264 150.0667 −1.49E+00 −4.17E−01 14 On A/Int; Off I Q9UHA4 195.0133 −1.89E+00 −1.41E−01 14 On A/Int; Off I P21397 312.5207 −3.81E+00 1.67E−01 14 On A/Int; Off I P55196 137.1449 −1.07E+00 2.56E−02 14 On A/Int; Off I Q12965 203.3655 −8.01E−01 3.75E−01 14 On A/Int; Off I Q9HBW1 300.2834 −2.27E+00 −7.79E−02 14 On A/Int; Off I Q9H2W4 299.9778 −2.26E+00 3.56E−01 14 On A/Int; Off I Q9NRR3 213.1256 −7.34E−01 7.49E−01 14 On A/Int; Off I P23511 199.2783 −8.54E−01 −8.06E−02 14 On A/Int; Off I Q99650 237.114 −1.26E+00 −5.33E−01 14 On A/Int; Off I P04085 343.2015 −1.83E+01 6.89E−02 14 On A/Int; Off I Q13048 145.8869 −8.25E−01 4.41E−01 14 On A/Int; Off I P10586 335.8682 −1.77E+00 −2.05E−01 14 On A/Int; Off I O95200 275.0752 −2.59E+00 −4.72E−01 14 On A/Int; Off I Q9NVX8 337.8544 −1.96E+00 1.72E−01 14 On A/Int; Off I Q15418 246.2347 −1.93E+00 2.68E−01 14 On A/Int; Off I Q15434 309.3377 −1.65E+00 −4.70E−01 14 On A/Int; Off I Q15437 214.4633 −1.15E+00 −2.58E−01 14 On A/Int; Off I O60679 152.8498 −1.70E+00 −5.63E−02 14 On A/Int; Off I Q12890 247.1823 −1.63E+00 −3.33E−01 14 On A/Int; Off I Q12971 224.3379 −1.35E+00 4.11E−01 14 On A/Int; Off I P78556 249.7105 −2.38E+00 3.10E−01 14 On A/Int; Off I O75751 156.4431 −1.30E+00 5.31E−01 14 On A/Int; Off I Q9UM01 172.4611 −1.85E+00 3.66E−01 14 On A/Int; Off I Q9Y5X1 189.2981 −1.01E+00 1.30E−01 14 On A/Int; Off I P08842 328.904 −1.68E+00 −7.62E−02 14 On A/Int; Off I O43760 249.1866 −1.73E+00 −7.14E−01 14 On A/Int; Off I O75674 205.2456 −2.35E+00 4.30E−02 14 On A/Int; Off I P01135 145.3108 −1.86E+00 −4.29E−01 14 On A/Int; Off I Q9NT70 298.7991 −1.50E+00 1.33E−01 14 On A/Int; Off I O60656 337.3961 −4.31E+00 −3.18E−01 14 On A/Int; Off I Q9NZ42 175.1842 −7.73E−01 1.15E−01 14 On A/Int; Off I O76080 200.0768 −2.08E+00 −5.80E−01 14 On A/Int; Off I Q13015 1272.138 2.41E+00 2.40E+00 6 On Acinar; Up Int = I P04083 5883.787 2.90E+00 2.89E+00 6 On Acinar; Up Int = I O60592 2304.427 3.56E−01 1.07E+00 6 On Acinar; Up Int = I Q07814 797.9572 1.35E+00 1.00E+00 6 On Acinar; Up Int = I Q14201 355.9496 1.08E+00 1.19E+00 6 On Acinar; Up Int = I Q9NR00 4453.955 2.47E−01 1.40E+00 6 On Acinar; Up Int = I Q9BUW7 476.5934 1.27E+00 1.51E+00 6 On Acinar; Up Int = I O95401 390.063 1.66E+00 1.08E+00 6 On Acinar; Up Int = I Q00535 392.629 6.80E−01 8.19E−01 6 On Acinar; Up Int = I P21741 9388.855 1.71E+00 2.36E+00 6 On Acinar; Up Int = I Q9Y291 290.8529 1.04E+00 8.93E−01 6 On Acinar; Up Int = I O75376 791.9381 9.54E−01 1.76E+00 6 On Acinar; Up Int = I P03973 2270.718 2.81E+00 1.80E+00 6 On Acinar; Up Int = I O15427 589.0175 1.78E+00 1.72E+00 6 On Acinar; Up Int = I P16949 1781.654 1.45E+00 1.85E+00 6 On Acinar; Up Int = I Q9NZ86 597.7198 7.86E−01 1.60E+00 6 On Acinar; Up Int = I O00748 517.9952 −2.09E+00 −2.30E+00 20 Other Q13630 388.1959 −1.28E+00 −1.12E+00 20 Other P00505 369.968 −9.25E−01 −4.75E−01 20 Other P50440 798.1958 −2.73E+00 −2.14E+00 20 Other P29622 304.9848 −8.00E−01 −1.29E+00 20 Other O14646 440.3418 −1.67E+00 −2.27E+00 20 Other P48307 521.385 −1.73E+00 −1.33E+00 20 Other Q15125 470.0852 −1.67E+00 −1.96E+00 20 Other P19387 211.5128 5.26E−01 −3.39E−01 20 Other Q9P0K7 245.4643 6.73E−01 6.26E−01 20 Other P30086 465.627 −1.08E+00 −4.57E−01 20 Other Q13045 476.5407 −1.02E+00 −3.14E−01 20 Other O95084 552.6166 −1.80E+00 −2.15E+00 20 Other P49770 536.2071 −1.15E+00 −4.19E−01 20 Other Q13948 300.5112 5.72E−01 6.50E−01 20 Other Q30201 278.446 7.26E−01 5.03E−01 20 Other P52895 1534.634 −3.56E+00 −3.93E+00 20 Other Q9Y5N1 356.7517 −6.26E−01 −1.38E+00 20 Other P43378 724.8175 −1.88E+00 −1.61E+00 20 Other P35414 474.2345 −6.49E−01 −6.12E−01 20 Other Q14802 1096.127 −2.43E+00 −1.61E+00 20 Other Q9Y266 533.6949 −8.68E−01 −7.37E−01 20 Other P30043 620.0433 −1.07E+00 −6.35E−01 20 Other Q9NP73 557.2055 −9.32E−01 −8.51E−01 20 Other Q12972 345.0523 7.61E−01 5.13E−01 20 Other Q9Y296 532.9995 −7.58E−01 −8.01E−01 20 Other Q02750 586.6635 −8.76E−01 −6.72E−01 20 Other P42226 619.5568 −9.87E−01 −7.92E−01 20 Other P31947 1378.205 −2.70E+00 −1.99E+00 20 Other P46597 1043.272 −2.25E+00 −2.35E+00 20 Other O14745 997.106 −1.87E+00 −1.52E+00 20 Other Q9NS67 813.4043 −1.30E+00 −1.94E+00 20 Other Q9UKL5 829.3129 −7.16E−01 −1.68E−01 20 Other Q9UQL3 860.8974 −4.44E−01 4.78E−01 20 Other Q9NZZ1 488.5944 6.37E−01 1.78E−01 20 Other Q9Y3Q3 504.2124 2.63E−01 −5.68E−01 20 Other Q9NSN3 431.8528 9.10E−01 −3.79E−01 20 Other Q9Y5Z0 1036.811 −1.11E+00 −6.14E−01 20 Other 699.9713 5.20E−01 7.41E−01 20 Other O14713 643.5596 7.25E−01 7.42E−01 20 Other P46095 1185.918 −1.62E+00 −2.34E+00 20 Other Q9BV10 1064.815 −1.18E+00 −1.43E+00 20 Other Q99653 1313.03 −1.11E+00 −2.59E−01 20 Other P41584 758.0427 5.53E−01 6.71E−01 20 Other P11940 1078.525 −1.07E+00 −1.38E+00 20 Other Q00341 618.5713 6.67E−01 −2.99E−01 20 Other Q16795 1214.409 −8.58E−01 −4.15E−01 20 Other Q13082 854.4272 −4.78E−01 −1.37E+00 20 Other P36405 665.1099 8.87E−01 1.07E−01 20 Other Q9NXH2 647.4269 8.97E−01 −1.44E−01 20 Other Q9Y323 1148.545 2.19E−01 9.59E−01 20 Other P48059 827.7691 8.40E−01 7.11E−01 20 Other Q9P0M9 846.5801 8.23E−01 6.93E−01 20 Other Q13813 1406.107 −1.08E+00 −1.35E+00 20 Other Q9Y379 1877.939 −1.12E+00 −4.26E−01 20 Other Q13247 1041.827 7.35E−01 7.55E−01 20 Other P14416 952.9439 6.73E−01 −1.28E−01 20 Other Q06323 1742.377 −1.05E−01 6.55E−01 20 Other Q9NR31 1008.646 8.82E−01 2.36E−01 20 Other P05451 26243.72 −5.76E+00 −5.48E+00 20 Other P04075 2532.66 −1.62E+00 −1.51E+00 20 Other Q15904 1228.765 8.21E−01 7.30E−01 20 Other P15559 775.5735 1.47E+00 −8.25E−01 20 Other O00303 1145.377 3.23E−01 −9.68E−01 20 Other P56705 2271.364 −1.13E+00 −1.18E+00 20 Other P39210 1202.587 7.99E−01 −1.47E−01 20 Other Q9UKL9 7016.796 −3.10E+00 −2.52E+00 20 Other O43516 1444.29 7.68E−01 3.51E−02 20 Other Q9Y470 1503.556 6.06E−01 −2.73E−01 20 Other P29312 4076.247 −1.15E+00 −1.40E−01 20 Other Q9Y5R8 1971.095 6.86E−01 1.32E−01 20 Other P17676 3890.676 −1.15E+00 −1.07E+00 20 Other O95362 5333.102 −1.84E+00 −1.96E+00 20 Other O60417 5248.939 −1.17E+00 −2.89E−01 20 Other P19623 2027.643 1.06E+00 −6.88E−01 20 Other Q9P039 3004.627 8.96E−01 −1.87E−01 20 Other Q9BUF5 2855.744 1.07E+00 −5.08E−01 20 Other P00995 28226.58 −3.65E+00 −2.59E+00 20 Other P11142 8144.601 −1.04E+00 −5.08E−01 20 Other P10620 4901.595 −2.68E−01 −1.47E+00 20 Other Q13347 10168.91 −1.79E+00 −1.91E+00 20 Other P15880 4127.437 4.54E−01 −1.08E+00 20 Other Q9HCU0 4295.784 1.19E+00 −2.72E−01 20 Other Q04941 12775.93 −1.07E+00 −6.04E−01 20 Other Q9UPI1 7300.387 9.60E−01 8.39E−01 20 Other P13987 15673.38 −7.34E−01 1.42E−01 20 Other P15951 31332.74 −2.72E+00 −3.30E+00 20 Other P04687 12871.67 −4.88E−02 −1.14E+00 20 Other P04687 15834.49 6.05E−01 −1.06E+00 20 Other Q9UI09 2210.196 7.19E−01 1.79E−01 3 Unchanged High Q9Y6H1 5191.628 3.77E−02 −4.90E−01 3 Unchanged High Q9P0U1 2721.439 7.28E−01 −2.21E−01 3 Unchanged High P80095 2471.592 −1.04E+00 −2.99E−01 3 Unchanged High Q92747 3972.89 −6.92E−01 −2.93E−01 3 Unchanged High O15144 17538.09 3.00E−01 6.17E−01 3 Unchanged High O15145 2683.638 −7.73E−01 5.78E−02 3 Unchanged High P02570 50171.41 −7.74E−01 −5.45E−01 3 Unchanged High P02570 50643.44 −5.42E−01 −6.16E−01 3 Unchanged High P02570 16331.85 −4.70E−01 −8.03E−01 3 Unchanged High P02571 64643.45 −7.47E−02 −2.27E−01 3 Unchanged High P12814 2400.844 1.36E−01 −1.50E−01 3 Unchanged High O43707 4769.196 −1.00E+00 −8.78E−01 3 Unchanged High P53999 4936.98 4.24E−01 −5.13E−02 3 Unchanged High P18848 6749.873 9.88E−02 −4.02E−01 3 Unchanged High P53680 2963.423 8.63E−01 1.67E−01 3 Unchanged High P29274 2318.367 1.05E−02 5.73E−01 3 Unchanged High P54819 2788.3 −7.20E−02 −2.53E−01 3 Unchanged High Q01518 8362.375 4.59E−02 6.59E−01 3 Unchanged High P32889 7056.851 3.88E−01 2.58E−01 3 Unchanged High P18085 7331.81 8.04E−01 8.93E−01 3 Unchanged High P26437 4052.262 9.17E−02 2.45E−01 3 Unchanged High Q9BZX4 2541.066 9.21E−02 2.44E−01 3 Unchanged High P11766 2354.247 3.62E−01 −1.59E−01 3 Unchanged High P05067 3649.558 4.61E−01 5.55E−01 3 Unchanged High Q06481 2546.598 1.13E−01 6.10E−01 3 Unchanged High P07355 94734.13 3.79E−01 5.86E−01 3 Unchanged High P08758 5295.976 6.69E−01 −7.32E−02 3 Unchanged High P55064 12248.87 1.02E−01 3.93E−01 3 Unchanged High Q13520 2404.397 3.12E−02 −3.25E−02 3 Unchanged High P32391 4171.013 −1.23E−01 −3.92E−03 3 Unchanged High O43776 2811.634 1.51E−01 2.27E−01 3 Unchanged High P24539 3312.717 1.50E−01 3.86E−01 3 Unchanged High P48201 4974.135 −2.29E−01 −3.82E−01 3 Unchanged High P05496 2112.628 1.41E−01 −3.06E−01 3 Unchanged High Q06055 5682.609 4.19E−01 −7.12E−01 3 Unchanged High O75947 2355.858 −5.04E−01 −8.37E−02 3 Unchanged High P56385 2462.524 −3.60E−02 −3.62E−01 3 Unchanged High P56134 14327.12 2.91E−01 5.71E−01 3 Unchanged High P18859 4633.559 4.16E−01 3.20E−01 3 Unchanged High O75964 2219.11 −8.99E−03 3.78E−01 3 Unchanged High P25705 3009.915 −3.02E−01 −6.05E−01 3 Unchanged High P06576 3305.047 −6.71E−01 −3.11E−01 3 Unchanged High P36542 2313.989 −2.54E−02 −2.91E−01 3 Unchanged High P48047 3955.838 −2.54E−01 −4.09E−02 3 Unchanged High Q01814 3193.535 3.84E−02 1.05E−02 3 Unchanged High Q99437 2817.803 −2.58E−01 6.33E−01 3 Unchanged High P36543 2145.908 −1.60E−01 6.57E−01 3 Unchanged High O75348 3704.42 −6.67E−03 1.05E+00 3 Unchanged High Q16864 10101.59 3.03E−01 1.30E+00 3 Unchanged High P27449 18185.04 −3.85E−01 5.04E−01 3 Unchanged High O00244 3435.675 4.89E−01 3.03E−01 3 Unchanged High O14503 4169.761 −6.13E−01 −2.20E−01 3 Unchanged High O60238 2371.407 1.13E+00 7.14E−01 3 Unchanged High P30536 2405.625 2.19E−01 5.34E−01 3 Unchanged High P01884 68478.91 −8.47E−01 6.88E−01 3 Unchanged High P22004 4509.317 −4.14E−01 −9.65E−02 3 Unchanged High O95415 8032.295 −4.87E−01 5.85E−01 3 Unchanged High O75531 2736.992 2.03E−01 1.11E−01 3 Unchanged High P02593 3482.215 1.59E+00 1.39E+00 3 Unchanged High P07384 3078.324 −5.21E−01 −5.61E−03 3 Unchanged High P27797 11797.33 5.89E−01 −8.16E−02 3 Unchanged High 23425.99 1.00E−01 4.75E−01 3 Unchanged High P47756 4604.9 2.06E−01 3.38E−02 3 Unchanged High P15086 3273.378 −8.50E+00 −8.49E+00 3 Unchanged High P52952 2292.94 −3.25E−01 −7.19E−01 3 Unchanged High P13862 3795.282 7.58E−02 6.25E−02 3 Unchanged High O14675 2092.229 −1.19E+00 −6.77E−02 3 Unchanged High P35221 3782.772 −2.08E−01 1.51E−01 3 Unchanged High P07858 3607.853 8.54E−01 6.37E−01 3 Unchanged High P48509 9901.71 2.71E−01 9.11E−01 3 Unchanged High P25063 15932.79 −1.36E+00 −2.28E−01 3 Unchanged High P16070 10533.43 −1.49E+00 −7.47E−01 3 Unchanged High P08962 10307.1 9.86E−02 3.04E−01 3 Unchanged High O14519 4389.995 1.71E−01 −1.90E−02 3 Unchanged High P25763 3426.736 −6.86E−01 −6.93E−01 3 Unchanged High P49368 2484.939 −8.46E−02 2.87E−01 3 Unchanged High P48643 2042.12 −5.20E−01 5.49E−02 3 Unchanged High O00299 6591.299 −2.50E−01 8.71E−02 3 Unchanged High Q9Y2Q7 4610.942 5.41E−01 −1.05E−01 3 Unchanged High P09496 6957.341 2.26E−02 6.86E−01 3 Unchanged High O95832 2138.383 −1.73E+00 −3.14E−01 3 Unchanged High O95471 2587.177 −9.25E−01 2.14E−01 3 Unchanged High P23528 16255.64 −1.68E−01 2.22E−01 3 Unchanged High P16989 2515.212 −5.08E−01 −2.16E−01 3 Unchanged High P38936 3777.57 −8.40E−02 2.23E−01 3 Unchanged High Q9UII4 31877.4 5.99E−01 1.87E−01 3 Unchanged High P04080 4034.272 −8.63E−01 3.30E−01 3 Unchanged High P21291 2109.096 −2.15E−01 −5.33E−01 3 Unchanged High O00622 2224.339 5.25E−01 −3.50E−01 3 Unchanged High P13073 7115.048 7.95E−02 4.60E−01 3 Unchanged High P12074 4434.13 3.84E−01 8.35E−01 3 Unchanged High Q02221 3464.904 6.33E−01 −7.28E−02 3 Unchanged High P14854 2344.331 2.57E−01 4.17E−01 3 Unchanged High P09669 2197.58 −4.21E−01 −3.08E−01 3 Unchanged High P14406 4530.346 −1.91E−01 −1.07E−01 3 Unchanged High O14548 2556.481 4.78E−01 1.64E−01 3 Unchanged High P24311 4057.995 2.38E−01 6.75E−01 3 Unchanged High P15954 11482.48 −3.20E−01 −1.27E−02 3 Unchanged High P10176 2750.974 1.41E−01 −6.65E−01 3 Unchanged High O43293 2157.783 −2.80E−01 −4.55E−01 3 Unchanged High P46966 9563.241 2.69E−01 5.02E−01 3 Unchanged High Q09753 4619.611 −9.19E−01 9.07E−01 3 Unchanged High P18282 7126.01 −3.45E−01 −3.09E−02 3 Unchanged High P07108 2422.578 2.38E−01 −5.54E−01 3 Unchanged High P31689 2402.398 −4.77E−01 2.32E−01 3 Unchanged High Q9Y5T4 2414.457 4.46E−02 1.17E−01 3 Unchanged High Q9Y463 7023.599 −4.56E−01 −2.57E−01 3 Unchanged High Q9NP97 4534.283 3.95E−01 2.63E−02 3 Unchanged High Q15701 4875.685 −5.25E−02 3.69E−01 3 Unchanged High P78545 2673.744 −1.38E+00 −4.42E−01 3 Unchanged High O60869 5094.856 −4.31E−01 4.19E−02 3 Unchanged High Q14259 4241.036 5.26E−01 1.38E−01 3 Unchanged High P06733 9983.774 −3.33E−01 −7.50E−01 3 Unchanged High P22712 5403.444 −4.60E−01 −6.85E−01 3 Unchanged High P04720 27648.74 −6.25E−01 −6.40E−01 3 Unchanged High P26641 8337.901 7.58E−01 −6.91E−02 3 Unchanged High P13639 3231.325 −2.60E−01 −8.01E−01 3 Unchanged High O15372 2398.394 −2.63E−01 −5.70E−01 3 Unchanged High O75821 3005.577 1.48E−01 −1.70E−01 3 Unchanged High Q64252 2141.68 −3.73E−01 −8.38E−01 3 Unchanged High O15371 3954.374 −2.64E−01 −8.46E−02 3 Unchanged High P04765 7083.99 −2.78E−01 −1.05E−01 3 Unchanged High Q14240 2267.015 2.68E−01 6.61E−02 3 Unchanged High P10159 6638.65 −6.75E−01 −7.84E−01 3 Unchanged High Q9NQT4 2331.056 1.35E−01 3.04E−01 3 Unchanged High P02794 42243.59 2.28E−01 4.41E−01 3 Unchanged High P02792 30568.13 −1.31E+00 −5.78E−01 3 Unchanged High Q05472 10145.46 −8.91E−02 1.19E−02 3 Unchanged High P20071 2009.291 −9.54E−01 −5.51E−01 3 Unchanged High P50395 2051.41 2.24E−03 −5.38E−01 3 Unchanged High P48507 2055.914 5.27E+00 −1.02E+00 3 Unchanged High P36969 3787.13 −1.28E−01 5.15E−01 3 Unchanged High P09211 6378.198 −6.52E−01 4.40E−01 3 Unchanged High P04406 37260.67 6.32E−01 4.11E−01 3 Unchanged High P04406 51621.55 6.05E−01 6.80E−01 3 Unchanged High P04406 15342.7 6.61E−01 3.07E−01 3 Unchanged High P43304 3023.392 −7.48E−02 −5.58E−01 3 Unchanged High P41250 4736.632 5.28E−01 −2.56E−01 3 Unchanged High P04895 8718.93 2.32E−01 2.61E−01 3 Unchanged High P24522 4105.138 2.83E−01 1.13E+00 3 Unchanged High Q92847 2508.414 −1.23E−01 −4.29E−01 3 Unchanged High P04901 6398.85 2.96E−02 4.08E−01 3 Unchanged High P25388 18939.85 −2.35E−01 −5.49E−01 3 Unchanged High P06351 2421.658 −2.61E−01 1.80E−01 3 Unchanged High P04792 36135.19 −3.92E−01 −2.83E−01 3 Unchanged High P11021 2976.537 3.46E−01 −1.01E+00 3 Unchanged High P38646 2417.791 −3.61E−01 −3.87E−01 3 Unchanged High Q9UK76 34286.74 6.42E−01 4.27E−01 3 Unchanged High P09651 2231.413 1.05E−03 −6.14E−01 3 Unchanged High Q9Y4J5 3320.487 −2.11E−02 −6.94E−01 3 Unchanged High P09429 2567.093 4.67E−01 −6.06E−01 3 Unchanged High P49773 7064.436 2.92E−01 3.70E−01 3 Unchanged High Q92769 2155.575 −4.56E−01 −1.43E−01 3 Unchanged High P17693 2225.106 −1.51E−01 4.42E−01 3 Unchanged High P17483 3095.004 5.08E−03 2.71E−01 3 Unchanged High Q9UL99 2621.286 −7.27E−01 −8.21E−01 3 Unchanged High Q9GZT3 3797.943 3.62E−01 1.66E−01 3 Unchanged High Q9NWY5 4915.419 9.94E−01 8.14E−01 3 Unchanged High Q9UI30 3819.313 5.51E−01 4.37E−01 3 Unchanged High Q9BQB6 5897.337 1.27E+00 5.87E−01 3 Unchanged High Q9BWJ5 2436.767 3.91E−01 2.79E−01 3 Unchanged High Q9Y683 2699.545 2.77E−01 1.73E−01 3 Unchanged High Q16665 2675.668 −1.22E+00 −2.62E−01 3 Unchanged High O75353 4129.098 −5.44E−01 4.01E−02 3 Unchanged High Q16270 15334.47 1.54E+00 1.82E+00 3 Unchanged High Q9Y287 9139.933 5.36E−01 6.03E−01 3 Unchanged High P56537 2476.062 −7.26E−01 3.32E−01 3 Unchanged High P26006 2249.026 −9.95E−01 3.62E−02 3 Unchanged High P05556 6216.314 −5.05E−02 −3.22E−01 3 Unchanged High Q01628 12669.24 −7.09E−01 3.23E−02 3 Unchanged High Q12905 2687.538 −2.30E−01 −3.32E−01 3 Unchanged High Q13907 2362.933 −2.57E−01 −8.38E−01 3 Unchanged High P33947 2281.692 1.24E+00 −4.12E−01 3 Unchanged High P00338 40260.24 −6.46E−02 −3.52E−01 3 Unchanged High P08865 8180.607 2.15E−01 −4.93E−01 3 Unchanged High Q08380 2719.794 3.94E−01 3.13E−01 3 Unchanged High O14949 3377.305 3.06E−01 2.71E−01 3 Unchanged High Q15012 4319.567 9.54E−01 7.36E−01 3 Unchanged High P14174 6337.062 2.87E−01 2.74E−01 3 Unchanged High P49006 8400.725 6.17E−01 8.22E−01 3 Unchanged High P30463 3281.592 −2.60E−01 8.55E−01 3 Unchanged High P10321 12044.89 1.88E−01 9.25E−01 3 Unchanged High P10321 13298.19 6.28E−01 1.59E+00 3 Unchanged High P10321 13868.02 −1.62E−01 3.53E−01 3 Unchanged High P13747 2460.503 −3.07E−01 1.33E−01 3 Unchanged High Q95HC0 4168.835 −6.21E−01 −2.90E−01 3 Unchanged High P13640 4624.849 −1.07E+00 −3.79E−01 3 Unchanged High P80297 5142.996 1.00E−01 1.22E−01 3 Unchanged High P02795 7340.215 2.85E−01 1.48E−01 3 Unchanged High O14880 5712.043 −2.66E−01 6.60E−01 3 Unchanged High Q9NYZ2 2527.436 −1.51E−01 1.98E−01 3 Unchanged High P26038 4212.427 −1.65E−01 1.03E−01 3 Unchanged High O15329 6068.269 2.62E−01 9.31E−02 3 Unchanged High P16475 47407.02 2.26E−02 8.99E−02 3 Unchanged High P19105 7764.994 −1.32E−01 4.04E−02 3 Unchanged High Q9UK23 2357.087 4.14E−01 5.05E−01 3 Unchanged High O15239 4005.894 3.79E−01 9.27E−01 3 Unchanged High O00483 6613.046 8.01E−01 8.70E−02 3 Unchanged High O75438 2212.932 8.04E−01 4.13E−01 3 Unchanged High O95168 2607.423 −2.79E−02 5.09E−01 3 Unchanged High O95298 2544.679 5.97E−01 5.71E−01 3 Unchanged High O43920 8594.08 3.61E−01 8.85E−01 3 Unchanged High Q13765 3363.371 4.77E−01 2.76E−01 3 Unchanged High Q15843 4098.747 2.63E−01 4.48E−01 3 Unchanged High Q9NX14 3902.8 5.46E−01 −1.41E−01 3 Unchanged High Q9Y2R6 2113.511 4.01E−01 3.49E−01 3 Unchanged High Q15668 2662.845 8.99E−01 1.26E+00 3 Unchanged High O14597 2697.108 4.23E−02 −4.27E−01 3 Unchanged High P15531 7143.349 2.36E−01 6.07E−02 3 Unchanged High P22392 5114.664 2.72E−03 2.35E−01 3 Unchanged High O00746 2927.223 9.60E−01 3.80E−02 3 Unchanged High O75534 3241.269 −3.46E−01 1.20E−02 3 Unchanged High Q9H9A1 4076.544 −9.93E−01 −8.56E−01 3 Unchanged High Q9NPE3 4771.656 3.86E−02 1.01E+00 3 Unchanged High P54368 7292.818 1.10E−01 −6.72E−02 3 Unchanged High Q9UH52 2181.482 −3.10E−01 −6.73E−03 3 Unchanged High Q15070 2031.796 −5.90E−01 2.08E−01 3 Unchanged High Q9H230 2199.367 −3.37E−01 8.69E−01 3 Unchanged High O60356 2150.631 6.27E−01 1.25E−01 3 Unchanged High P78337 14411.94 −9.05E−02 −2.12E−01 3 Unchanged High Q9C086 3872.969 7.45E−01 2.72E−01 3 Unchanged High Q15165 2394.717 6.78E−01 1.49E+00 3 Unchanged High P20962 2722.317 5.73E−01 −8.88E−03 3 Unchanged High P23284 6683.166 7.47E−01 1.45E−01 3 Unchanged High Q06830 2493.75 −5.32E−01 −2.79E−01 3 Unchanged High P32119 3130.835 −1.05E−01 8.37E−02 3 Unchanged High P30048 2035.218 −5.34E−01 −2.66E−01 3 Unchanged High Q13162 2822.139 4.10E−01 −4.03E−01 3 Unchanged High P30044 2581.24 −3.63E−01 7.94E−01 3 Unchanged High Q13492 2414.998 −5.31E−01 3.03E−03 3 Unchanged High P08237 2533.875 2.00E−02 −4.94E−01 3 Unchanged High P00558 5552.736 2.90E−01 −1.57E−02 3 Unchanged High P18669 2477.75 6.30E−01 5.61E−01 3 Unchanged High Q14801 20128.93 −2.39E−01 −4.23E−01 3 Unchanged High O14832 7819.036 1.86E−01 8.57E−02 3 Unchanged High P53801 4627.881 −7.19E−02 2.80E−01 3 Unchanged High Q9HB21 2766.359 3.27E−01 4.07E−01 3 Unchanged High Q15365 3635.431 −5.49E−01 −5.60E−01 3 Unchanged High P52433 3198.285 7.62E−01 8.09E−01 3 Unchanged High P52436 2489.343 3.26E−01 2.65E−01 3 Unchanged High Q03052 2740.913 −5.61E−01 −3.26E−01 3 Unchanged High 5487.085 −1.41E+00 −1.01E−01 3 Unchanged High P40425 2958.976 2.77E−01 −9.05E−02 3 Unchanged High Q99471 2275.038 6.34E−01 2.41E−01 3 Unchanged High Q9UHZ2 2234.209 −1.48E−01 7.46E−01 3 Unchanged High P07737 37970.06 2.55E−01 7.21E−01 3 Unchanged High Q92740 4622.898 1.13E−02 3.41E−01 3 Unchanged High P07478 57240.67 −5.80E−01 −8.60E−01 3 Unchanged High Q9UL46 3648.995 −4.41E−01 3.06E−01 3 Unchanged High P25786 2369.437 −2.75E−03 1.80E−01 3 Unchanged High P20618 3082.003 −7.52E−03 3.40E−01 3 Unchanged High P49720 2081.991 5.06E−01 2.89E−01 3 Unchanged High P28070 2058.212 2.04E−02 −3.20E−01 3 Unchanged High Q99436 3566.368 −4.44E−01 −2.78E−01 3 Unchanged High P08129 2339.797 −1.60E−01 −2.09E−01 3 Unchanged High O15355 4605.064 −6.65E−01 −4.89E−01 3 Unchanged High P30153 3572.89 −4.81E−01 8.58E−02 3 Unchanged High Q15249 11954.68 −1.90E−01 3.50E−01 3 Unchanged High Q9NQ11 2501.162 −2.89E−01 −1.75E−01 3 Unchanged High P41567 7666.779 2.51E−01 −1.81E−01 3 Unchanged High Q15181 3978.537 −8.82E−01 −1.75E−01 3 Unchanged High P14786 7787.922 5.13E−01 3.54E−01 3 Unchanged High P57735 3198.699 −1.29E+00 5.47E−01 3 Unchanged High P54725 2026.126 −5.31E−01 −5.00E−01 3 Unchanged High P54727 4809.132 3.03E−01 4.20E−01 3 Unchanged High O00538 2210.191 −3.44E−01 −6.90E−02 3 Unchanged High P06749 2358.668 4.91E−01 −1.43E−01 3 Unchanged High P08134 3943.029 −5.88E−01 2.91E−02 3 Unchanged High 7033.479 7.34E−01 2.72E−01 3 Unchanged High P15154 10202.94 −1.11E−01 −1.59E−01 3 Unchanged High Q15347 2244.978 6.02E−01 4.63E−01 3 Unchanged High O95197 3654.06 4.61E−02 −1.20E−01 3 Unchanged High P09455 3023.27 1.08E−01 1.02E+00 3 Unchanged High P52565 3169.009 −1.13E−02 1.52E−02 3 Unchanged High P27635 10536.25 −2.72E−01 −9.17E−01 3 Unchanged High P53025 18124.91 4.14E−02 −3.63E−01 3 Unchanged High P39026 10427.07 −4.54E−01 −1.07E+00 3 Unchanged High P30050 33860.13 1.10E−02 −6.45E−01 3 Unchanged High P40429 24735.85 2.43E−01 −9.73E−02 3 Unchanged High P50914 16402.14 −2.00E−01 −3.43E−01 3 Unchanged High P39030 9104.589 3.62E−01 −5.43E−02 3 Unchanged High P18621 9074.168 1.89E−01 −5.71E−02 3 Unchanged High Q07020 12658.45 3.60E−01 −2.56E−01 3 Unchanged High Q02543 26796.74 1.74E−01 1.25E−01 3 Unchanged High P14118 5762.718 −1.70E−01 −1.72E−01 3 Unchanged High P46778 13222.79 5.86E−01 7.72E−02 3 Unchanged High P35268 17168.94 2.21E−01 −5.63E−03 3 Unchanged High P23131 22356.23 2.95E−01 −4.24E−02 3 Unchanged High P29316 5556.302 −2.29E−01 −4.01E−01 3 Unchanged High P38663 6488.503 −5.11E−01 −3.37E−01 3 Unchanged High P08526 9469.252 −3.28E−01 −1.29E+00 3 Unchanged High P46776 18008.07 3.85E−01 8.57E−02 3 Unchanged High P46779 39577.25 1.76E−01 −3.24E−01 3 Unchanged High P47914 2417.223 −7.81E−01 −7.73E−01 3 Unchanged High P39023 12535.38 8.18E−02 −3.36E−01 3 Unchanged High P04645 17188.03 2.83E−01 −5.20E−01 3 Unchanged High P12947 10441.63 3.69E−01 −1.18E−01 3 Unchanged High P02433 25982.45 4.33E−01 1.01E−01 3 Unchanged High P49207 12661.96 −6.27E−03 −1.99E−01 3 Unchanged High P42766 10527.37 2.75E−02 2.47E−03 3 Unchanged High P18077 11356.13 −7.27E−01 −4.50E−01 3 Unchanged High P09896 9742.196 5.22E−01 6.44E−02 3 Unchanged High P09896 5203.379 −1.39E−01 1.54E−01 3 Unchanged High P02403 39386.47 3.73E−01 4.95E−01 3 Unchanged High P12751 18651.98 9.74E−02 −1.05E−01 3 Unchanged High P23411 6091.715 5.54E−01 1.12E−01 3 Unchanged High P02404 19427.01 6.94E−01 5.96E−01 3 Unchanged High P36578 11723.95 −4.59E−01 −4.72E−01 3 Unchanged High P28751 36614.61 2.00E−01 −3.32E−02 3 Unchanged High P46777 10411.06 −2.13E−01 −4.35E−01 3 Unchanged High Q02878 11094.61 −6.48E−01 −1.12E+00 3 Unchanged High P18124 18885.03 −1.20E−01 −4.18E−01 3 Unchanged High P11518 10736.39 −3.38E−01 −7.00E−01 3 Unchanged High P25120 22208.81 7.08E−02 −3.67E−01 3 Unchanged High P32969 32766.75 3.70E−01 1.56E−01 3 Unchanged High P46783 7540.695 1.13E−02 3.89E−02 3 Unchanged High P04643 14209.6 2.07E−02 2.14E−01 3 Unchanged High P25398 13018.69 −3.95E−01 −6.11E−01 3 Unchanged High Q02546 13946.74 1.32E−01 −1.48E−01 3 Unchanged High P11174 21408.92 1.30E−01 −1.24E−01 3 Unchanged High P39027 17912.92 3.81E−01 −1.53E−01 3 Unchanged High P17008 22257.3 −1.20E−01 −7.62E−01 3 Unchanged High P08708 12443.09 1.36E−01 −8.07E−01 3 Unchanged High P25232 15089.7 6.78E−01 6.84E−03 3 Unchanged High P17075 24400.98 5.16E−01 −1.43E−01 3 Unchanged High P35265 10847.43 −6.38E−01 −5.69E−01 3 Unchanged High P39028 12545.6 2.51E−01 −1.72E−01 3 Unchanged High P16632 12699.84 −8.96E−02 1.53E−02 3 Unchanged High P25111 5677.337 −2.92E−01 −1.55E−01 3 Unchanged High P02383 25499.92 −4.27E−01 2.42E−01 3 Unchanged High P42677 16927.4 2.15E−01 −4.51E−01 3 Unchanged High P14798 3073.17 −2.52E−01 −4.77E−02 3 Unchanged High P25112 30318.47 −9.09E−02 7.66E−02 3 Unchanged High P30054 21630.2 4.69E−01 1.79E−01 3 Unchanged High P23396 4754.218 −9.85E−02 −1.07E+00 3 Unchanged High P49241 7316.667 2.64E−01 −2.06E−01 3 Unchanged High P12750 19282.5 1.36E−01 −2.87E−01 3 Unchanged High P22090 2580.924 7.98E−02 −1.72E−01 3 Unchanged High P46782 14598.96 1.70E−01 −4.85E−01 3 Unchanged High P10660 37695.24 −1.94E−01 −8.30E−01 3 Unchanged High P23821 16494.24 −4.00E−01 −2.19E−01 3 Unchanged High P09058 16406.16 3.97E−01 −3.76E−01 3 Unchanged High P46761 5285.193 −1.21E−01 −6.63E−01 3 Unchanged High P46781 11278.36 7.93E−01 1.38E−01 3 Unchanged High P46781 5525.883 −6.62E−01 −2.34E+00 3 Unchanged High P05387 15695.14 9.78E−02 −3.87E−01 3 Unchanged High P05388 16430.54 2.05E−01 −4.64E−01 3 Unchanged High P05386 2413.78 4.92E−01 −2.46E−01 3 Unchanged High Q9Y254 3408.892 3.74E−01 7.15E−01 3 Unchanged High Q9NWJ8 2666.66 8.79E−02 9.99E−01 3 Unchanged High P08206 40017.88 −2.78E−01 3.72E−01 3 Unchanged High P31949 8466.714 −7.17E−01 3.20E−01 3 Unchanged High P06703 3188.753 −7.04E−01 2.60E−01 3 Unchanged High P55735 2016.062 4.79E−01 2.32E−01 3 Unchanged High P38384 6908.432 3.60E−01 4.67E−01 3 Unchanged High Q9NZJ3 2230.091 −1.14E+00 −2.60E−01 3 Unchanged High O15532 3189.642 5.49E−01 1.50E−01 3 Unchanged High Q13501 2517.543 −1.47E+00 −1.82E−02 3 Unchanged High P35237 5105.477 −5.17E−01 9.60E−01 3 Unchanged High P05121 6972.284 1.04E+00 7.09E−01 3 Unchanged High Q00587 2393.46 −2.79E−01 9.80E−02 3 Unchanged High Q9H299 15134.74 −6.90E−02 2.43E−01 3 Unchanged High P37108 28082.56 −3.96E−04 5.49E−01 3 Unchanged High P49458 2551.928 7.45E−01 4.93E−01 3 Unchanged High P43308 4898.581 4.81E−01 1.31E−01 3 Unchanged High P51571 2349.29 3.65E−01 1.77E−01 3 Unchanged High O00422 2396.002 −2.67E−01 5.83E−02 3 Unchanged High O75918 6955.245 4.19E−01 2.42E−01 3 Unchanged High P13500 21330.26 −9.59E−01 1.16E+00 3 Unchanged High Q15356 2570.901 3.96E−02 −3.52E−01 3 Unchanged High P14648 2021.429 1.39E+00 1.64E+00 3 Unchanged High P12236 6107.995 −2.58E−01 −6.32E−01 3 Unchanged High Q00325 4200.626 −4.25E−01 −4.37E−01 3 Unchanged High P32745 4340.964 2.11E−01 2.39E−02 3 Unchanged High P30626 2323.149 2.67E−01 5.59E−01 3 Unchanged High Q01826 30645.09 −1.27E−01 6.42E−01 3 Unchanged High P21673 10275.93 −4.74E−01 9.80E−01 3 Unchanged High P34991 2820.643 −3.59E−01 −3.80E−02 3 Unchanged High P23246 2834.056 3.13E−01 −1.32E−01 3 Unchanged High P35716 4001.241 −1.24E+00 −4.71E−02 3 Unchanged High P35713 2565.998 −3.48E−01 2.66E−01 3 Unchanged High Q06945 2049.214 −4.91E−01 −5.59E−02 3 Unchanged High P00441 4202.954 −4.55E−01 1.51E−01 3 Unchanged High P50502 2400.085 3.12E−02 1.35E−01 3 Unchanged High Q9Y5Y6 2183.041 −6.58E−01 1.93E−01 3 Unchanged High P17600 2067.417 3.03E−02 1.74E−01 3 Unchanged High O43759 11775.53 −5.29E−01 −4.33E−01 3 Unchanged High Q12962 4992.528 −5.83E−01 −2.26E−01 3 Unchanged High Q15763 2600.459 5.12E−01 5.16E−01 3 Unchanged High P10599 9965.777 −8.40E−01 5.00E−02 3 Unchanged High P13472 58508.68 2.08E−01 6.61E−01 3 Unchanged High P01253 21783.42 −5.12E−01 1.66E−01 3 Unchanged High Q01085 2312.331 3.74E−01 −3.47E−01 3 Unchanged High Q15370 3505.384 5.83E−01 6.05E−01 3 Unchanged High O43680 2209.014 7.67E−01 3.49E−03 3 Unchanged High P21980 2827.774 −7.53E−01 1.58E−01 3 Unchanged High P29401 2671.504 −2.63E−01 −6.75E−01 3 Unchanged High O60739 3315.099 5.34E−01 3.50E−01 3 Unchanged High Q9NS69 3062.809 3.29E−01 −2.89E−01 3 Unchanged High P00938 6622.243 5.50E−01 2.97E−02 3 Unchanged High P07226 2897.509 5.11E−01 −1.97E−01 3 Unchanged High P04687 18992.31 1.42E−01 −4.84E−01 3 Unchanged High P04687 15193.76 5.59E−01 −9.60E−01 3 Unchanged High Q13509 2394.89 −3.36E−01 3.56E−01 3 Unchanged High P04350 5149.498 −1.14E+00 −7.75E−01 3 Unchanged High O75347 3390.719 1.27E−01 3.77E−01 3 Unchanged High O75509 3007.078 −2.55E−01 1.12E+00 3 Unchanged High P13693 49731.11 2.81E−01 6.10E−01 3 Unchanged High P14625 3049.346 1.17E+00 −8.69E−02 3 Unchanged High P42655 5956.713 −2.44E−01 −2.01E−01 3 Unchanged High Q04917 7111.932 −9.18E−01 −8.07E−02 3 Unchanged High P29312 4275.506 −1.37E+00 −3.29E−01 3 Unchanged High P29312 2406.497 −1.59E+00 −2.01E+00 3 Unchanged High O14957 3351.45 2.88E−01 5.49E−01 3 Unchanged High P14793 2840.732 −1.18E−01 −1.03E+00 3 Unchanged High P02248 3779.352 5.92E−01 6.86E−01 3 Unchanged High O76069 2068.646 1.52E−01 −1.46E−02 3 Unchanged High Q9BZL1 6239.513 2.83E−01 1.07E+00 3 Unchanged High P08670 10813.94 1.58E+00 5.53E−01 3 Unchanged High P45880 6347.014 −5.58E−01 5.49E−02 3 Unchanged High Q9Y277 2216.75 4.66E−01 2.48E−01 3 Unchanged High P17861 2347.333 −7.36E−01 −1.08E+00 3 Unchanged High O43670 3226.643 −7.15E−02 −7.67E−02 3 Unchanged High Q07352 5601.518 −2.98E−01 −8.49E−02 3 Unchanged High Q15942 2387.987 −2.86E−02 −3.09E−01 3 Unchanged High Q16659 128.6073 −5.32E−01 −3.51E−02 1 Unchanged Low O75324 134.7009 −3.97E−01 3.88E−01 1 Unchanged Low Q9BYP8 150.0893 −8.18E−01 −2.33E−02 1 Unchanged Low P55291 128.8583 −6.62E−01 −3.16E−01 1 Unchanged Low P49768 117.5823 −3.51E−01 −4.04E−02 1 Unchanged Low P55107 127.9343 −1.89E−01 5.54E−01 1 Unchanged Low P17082 236.7776 −2.10E+00 −1.30E+00 1 Unchanged Low P23634 185.4081 −8.30E−01 6.21E−01 1 Unchanged Low P78347 118.6963 −5.87E−01 −5.52E−01 1 Unchanged Low P09912 444.3716 −8.61E−01 2.51E+00 1 Unchanged Low Q9H2F5 114.5773 −3.30E−01 −1.48E−01 1 Unchanged Low O14811 128.8019 −5.85E−01 −2.02E−01 1 Unchanged Low O60942 125.1735 −7.98E−01 −8.65E−01 1 Unchanged Low Q9Y5Y3 145.8365 −7.75E−01 −1.12E−01 1 Unchanged Low P11908 147.2722 −7.05E−01 6.46E−02 1 Unchanged Low Q92851 115.0308 −4.15E−01 −3.42E−01 1 Unchanged Low Q9BQE5 119.8218 −1.06E−01 4.26E−01 1 Unchanged Low P55327 116.9522 −4.16E−01 −2.77E−01 1 Unchanged Low P28332 114.0924 −4.79E−01 −5.43E−01 1 Unchanged Low O95861 115.4153 −3.27E−01 −1.44E−01 1 Unchanged Low Q9NXJ5 125.322 −2.59E−01 3.05E−01 1 Unchanged Low Q15642 121.6641 −2.41E−01 2.30E−01 1 Unchanged Low O94997 138.8592 −7.69E−01 −3.17E−01 1 Unchanged Low O95453 115.7147 −4.52E−01 −4.16E−01 1 Unchanged Low Q9H9C5 121.5247 −4.07E−01 −1.05E−01 1 Unchanged Low P10451 123.2388 −8.94E−01 −1.31E+00 1 Unchanged Low P53992 113.9998 −3.89E−01 −3.53E−01 1 Unchanged Low Q9NQW1 123.8833 −1.18E−01 5.02E−01 1 Unchanged Low Q01449 150.5611 −7.97E−01 −7.94E−02 1 Unchanged Low Q9NX46 123.8664 −8.73E−02 5.37E−01 1 Unchanged Low P53609 123.8135 −4.41E−01 −1.26E−01 1 Unchanged Low Q15029 115.9932 −2.10E−01 7.28E−02 1 Unchanged Low P50458 122.9669 −5.00E−01 −2.84E−01 1 Unchanged Low P33764 152.5858 −5.43E−01 4.36E−01 1 Unchanged Low Q9P289 117.7841 −3.68E−01 −1.98E−01 1 Unchanged Low P52429 118.2956 −3.15E−01 −6.96E−02 1 Unchanged Low P54578 124.2132 −6.33E−01 −5.71E−01 1 Unchanged Low Q13219 123.4254 −1.21E−01 4.44E−01 1 Unchanged Low O60547 119.8044 −5.05E−01 −4.43E−01 1 Unchanged Low P23297 124.9008 −4.83E−01 −2.10E−01 1 Unchanged Low Q9H5J8 137.2762 −1.05E+00 −1.24E+00 1 Unchanged Low Q14493 128.4702 −2.84E−01 2.85E−01 1 Unchanged Low Q9NZU0 219.1816 −1.45E+00 −8.65E−02 1 Unchanged Low P80370 114.6185 −6.18E−01 −1.00E+00 1 Unchanged Low Q9NYV4 113.4542 −3.01E−01 −2.60E−01 1 Unchanged Low P09016 156.5829 −7.31E−01 1.50E−01 1 Unchanged Low Q13873 115.6624 −5.77E−01 −8.45E−01 1 Unchanged Low O14878 116.398 −2.58E−01 −5.89E−02 1 Unchanged Low P52848 118.3793 −6.70E−01 −9.77E−01 1 Unchanged Low Q14848 121.4689 −2.50E−01 1.27E−01 1 Unchanged Low O00204 135.653 −8.31E−01 −6.71E−01 1 Unchanged Low P35610 112.1404 −4.60E−01 −7.08E−01 1 Unchanged Low Q04760 114.7132 −3.43E−01 −3.12E−01 1 Unchanged Low P51690 119.2772 −7.59E−01 −1.22E+00 1 Unchanged Low P26012 128.4899 −8.19E−02 6.19E−01 1 Unchanged Low Q14978 117.4911 −1.61E−01 1.61E−01 1 Unchanged Low O00764 135.073 −6.14E−01 −1.92E−01 1 Unchanged Low Q9Y6Q5 120.3004 −5.12E−01 −4.85E−01 1 Unchanged Low O95350 122.6314 −3.90E−01 −1.26E−01 1 Unchanged Low P49748 122.4441 −2.09E−01 2.23E−01 1 Unchanged Low P08100 115.4338 −2.58E−01 −1.10E−01 1 Unchanged Low Q15477 131.0636 3.14E−02 8.58E−01 1 Unchanged Low O43520 131.8072 −9.26E−01 −1.12E+00 1 Unchanged Low Q13039 120.383 −7.45E−01 −1.13E+00 1 Unchanged Low O15291 185.7368 −1.40E+00 −6.52E−01 1 Unchanged Low Q9NR71 122.091 −5.43E−02 4.84E−01 1 Unchanged Low O60884 188.5763 −1.08E+00 1.05E−01 1 Unchanged Low Q9BYE0 113.6134 −2.87E−01 −2.39E−01 1 Unchanged Low Q9Y272 124.0354 5.29E−02 7.13E−01 1 Unchanged Low Q9BUR5 140.65 4.24E−01 1.61E+00 1 Unchanged Low O60859 115.3513 −2.39E−01 −8.28E−02 1 Unchanged Low Q9GZU1 144.4516 3.01E−01 1.51E+00 1 Unchanged Low P19878 310.3051 −1.56E+00 7.31E−01 1 Unchanged Low Q13277 136.1937 −1.72E−01 6.41E−01 1 Unchanged Low 120.0361 −3.14E−01 −7.76E−02 1 Unchanged Low P32456 118.8515 −5.54E−02 3.76E−01 1 Unchanged Low Q9H4M9 134.9992 −5.00E−01 1.54E−02 1 Unchanged Low Q9BTX7 126.203 −1.37E−01 4.40E−01 1 Unchanged Low Q9NVN2 114.476 −2.31E−01 −1.17E−01 1 Unchanged Low Q99758 163.1362 −1.18E+00 −7.14E−01 1 Unchanged Low P43694 124.6996 −2.93E−02 5.77E−01 1 Unchanged Low Q13825 123.0884 −2.25E−01 1.83E−01 1 Unchanged Low Q92550 138.2365 −9.02E−01 −8.24E−01 1 Unchanged Low Q9UJS0 121.1782 −1.72E−01 2.17E−01 1 Unchanged Low Q99611 134.292 −6.73E−01 −3.99E−01 1 Unchanged Low P17275 112.2701 −3.60E−01 −5.18E−01 1 Unchanged Low Q13477 114.7415 −2.71E−01 −2.11E−01 1 Unchanged Low Q14692 117.1898 −1.12E−01 1.95E−01 1 Unchanged Low P49908 116.7316 −4.08E−01 −4.41E−01 1 Unchanged Low P54803 113.8221 −2.99E−01 −3.11E−01 1 Unchanged Low P50991 138.5613 −6.06E−01 −1.23E−01 1 Unchanged Low P35548 137.5011 −7.83E−01 −5.57E−01 1 Unchanged Low P11309 113.8227 −3.63E−01 −4.62E−01 1 Unchanged Low O75570 117.597 −2.81E−01 −1.31E−01 1 Unchanged Low Q9NY61 116.8527 −1.81E−01 4.36E−02 1 Unchanged Low Q9BTY8 112.876 −3.94E−01 −5.87E−01 1 Unchanged Low Q9NWS2 143.0354 −7.85E−01 −3.89E−01 1 Unchanged Low O00180 119.3824 −2.85E−01 −8.14E−02 1 Unchanged Low O15382 112.8868 −3.64E−01 −5.19E−01 1 Unchanged Low Q9Y2Z1 153.067 −5.57E−01 3.28E−01 1 Unchanged Low Q9Y315 117.8557 −3.48E−01 −2.89E−01 1 Unchanged Low Q9Y592 115.3792 −1.53E−01 2.56E−02 1 Unchanged Low Q9NYT0 124.8364 −1.07E−01 4.10E−01 1 Unchanged Low Q9Y343 116.6438 −2.04E−01 −3.60E−02 1 Unchanged Low Q9BVI4 123.6298 −3.96E−01 −1.88E−01 1 Unchanged Low P30622 119.7985 −1.27E−01 2.15E−01 1 Unchanged Low Q08345 212.6497 −1.32E+00 −1.35E−02 1 Unchanged Low P33176 114.5075 −2.05E−01 −1.33E−01 1 Unchanged Low P55273 126.8971 1.08E−01 8.01E−01 1 Unchanged Low Q9NW92 150.3287 −7.21E−01 −9.00E−02 1 Unchanged Low Q9NZC3 121.8015 2.21E−02 5.23E−01 1 Unchanged Low P15172 116.7347 −3.05E−01 −2.72E−01 1 Unchanged Low P27144 116.7128 −1.40E−01 6.42E−02 1 Unchanged Low O60508 129.259 −4.81E−01 −2.09E−01 1 Unchanged Low Q14012 118.8965 −8.21E−02 2.46E−01 1 Unchanged Low P98179 113.6891 −3.79E−01 −5.89E−01 1 Unchanged Low Q13223 124.3969 −4.78E−01 −3.79E−01 1 Unchanged Low P55198 138.7788 −7.46E−01 −5.69E−01 1 Unchanged Low P46459 114.1635 −3.66E−01 −5.37E−01 1 Unchanged Low P34969 169.3507 −1.02E+00 −2.70E−01 1 Unchanged Low Q14667 145.1883 2.58E−02 1.07E+00 1 Unchanged Low Q92830 114.5758 −2.63E−01 −2.83E−01 1 Unchanged Low 124.4395 −5.87E−02 4.45E−01 1 Unchanged Low O43252 163.4169 −8.50E−01 −5.02E−02 1 Unchanged Low Q9NS93 160.8518 −3.55E−01 7.76E−01 1 Unchanged Low O60616 215.0608 −2.81E+00 −3.35E+00 1 Unchanged Low P02261 112.4051 −4.26E−01 −7.87E−01 1 Unchanged Low Q14701 178.2467 −1.40E−01 1.37E+00 1 Unchanged Low Q9P025 134.6437 −5.67E−01 −2.44E−01 1 Unchanged Low P06702 138.5985 −4.19E−01 1.70E−01 1 Unchanged Low Q9Y5Q9 155.7377 −3.56E−01 6.68E−01 1 Unchanged Low P19075 113.7491 −2.54E−01 −3.30E−01 1 Unchanged Low O60905 119.4574 −2.73E−02 3.27E−01 1 Unchanged Low Q13322 114.7351 −1.53E−01 −7.64E−02 1 Unchanged Low Q9UQ09 134.0152 −8.06E−01 −8.89E−01 1 Unchanged Low P57053 140.5964 −6.07E−02 8.11E−01 1 Unchanged Low Q92876 145.5667 −8.57E−01 −5.97E−01 1 Unchanged Low P09960 130.2822 1.78E−01 9.44E−01 1 Unchanged Low Q9HBH1 112.7249 −3.40E−01 −6.01E−01 1 Unchanged Low P55082 118.1545 −1.54E−01 2.87E−02 1 Unchanged Low Q9NVH6 121.828 −6.79E−01 −1.10E+00 1 Unchanged Low O95249 119.983 2.10E−02 4.12E−01 1 Unchanged Low Q13891 118.5076 −2.14E−01 −8.18E−02 1 Unchanged Low Q9BZM5 162.5485 −2.91E−01 8.73E−01 1 Unchanged Low O94913 131.7517 −9.13E−01 −1.36E+00 1 Unchanged Low Q12987 119.3623 −2.72E−01 −1.81E−01 1 Unchanged Low Q92499 136.6656 −6.91E−01 −5.13E−01 1 Unchanged Low Q13686 119.4385 5.32E−02 4.42E−01 1 Unchanged Low P43250 114.2814 −1.37E−01 −9.10E−02 1 Unchanged Low Q9UMX0 124.0398 −1.55E−01 2.04E−01 1 Unchanged Low O94905 114.8261 −2.22E−01 −2.57E−01 1 Unchanged Low Q9UHK0 118.2396 −5.22E−01 −8.46E−01 1 Unchanged Low P25189 117.3068 −1.13E−02 2.52E−01 1 Unchanged Low Q10567 168.4738 −9.28E−01 −1.62E−01 1 Unchanged Low O15230 120.9363 −2.63E−02 3.35E−01 1 Unchanged Low P52294 152.7331 −7.01E−01 −7.70E−02 1 Unchanged Low O60668 114.8794 −1.68E−01 −1.56E−01 1 Unchanged Low P11688 121.0017 −3.05E−01 −2.19E−01 1 Unchanged Low Q9NWB6 119.9579 −6.66E−01 −1.22E+00 1 Unchanged Low Q9H028 118.4626 3.52E−02 3.57E−01 1 Unchanged Low Q9UMZ2 118.5628 −1.26E−01 −1.32E−02 1 Unchanged Low P24752 146.8035 −9.71E−01 −9.23E−01 1 Unchanged Low P11230 122.607 5.50E−02 5.11E−01 1 Unchanged Low O14977 119.7626 −1.21E−01 1.06E−01 1 Unchanged Low 364.6946 −3.41E−01 2.59E+00 1 Unchanged Low P56937 137.3284 −1.04E+00 −1.61E+00 1 Unchanged Low O75299 117.1803 −3.61E−02 1.78E−01 1 Unchanged Low P16219 118.69 1.17E−02 3.16E−01 1 Unchanged Low Q9NZ48 137.2614 −2.80E−02 7.46E−01 1 Unchanged Low Q9P163 123.4514 1.27E−01 6.51E−01 1 Unchanged Low Q9BVT8 127.7419 −2.95E−01 1.76E−02 1 Unchanged Low Q99933 115.0469 −1.15E−01 −5.98E−02 1 Unchanged Low O14645 160.4204 −5.71E−01 3.31E−01 1 Unchanged Low Q9BRR9 115.1711 −1.23E−01 −7.10E−02 1 Unchanged Low Q9Y3E7 157.1807 −5.18E−01 3.54E−01 1 Unchanged Low P46976 118.5706 −2.06E−01 −1.21E−01 1 Unchanged Low O75928 127.4786 1.64E−01 8.06E−01 1 Unchanged Low Q9NX63 131.146 −1.55E−01 3.68E−01 1 Unchanged Low Q9UBS0 150.9199 −7.54E−01 −2.71E−01 1 Unchanged Low Q15185 117.54 −6.12E−01 −1.23E+00 1 Unchanged Low O60516 120.8526 8.76E−02 4.97E−01 1 Unchanged Low Q16651 190.1399 −1.59E+00 −1.41E+00 1 Unchanged Low P48788 114.1376 −1.30E−01 −1.40E−01 1 Unchanged Low Q01968 125.3025 −6.07E−01 −8.17E−01 1 Unchanged Low Q9H6Z6 117.2667 −5.26E−02 1.25E−01 1 Unchanged Low Q9NQ55 117.676 −1.41E−01 −3.50E−02 1 Unchanged Low O95359 119.4624 3.79E−02 3.62E−01 1 Unchanged Low P01189 115.5442 −3.84E−01 −6.82E−01 1 Unchanged Low Q9Y525 123.6546 −9.82E−02 2.42E−01 1 Unchanged Low Q9UHC9 118.9021 4.79E−02 3.53E−01 1 Unchanged Low Q9HBT2 118.9743 −4.05E−01 −5.90E−01 1 Unchanged Low O00219 141.641 −1.01E+00 −1.34E+00 1 Unchanged Low P22735 113.1407 −2.95E−01 −5.89E−01 1 Unchanged Low O15388 121.3043 8.41E−02 4.82E−01 1 Unchanged Low O95389 113.4959 −2.73E−01 −5.21E−01 1 Unchanged Low Q06190 116.2494 −2.69E−01 −3.98E−01 1 Unchanged Low P50226 120.0792 −4.01E−01 −5.52E−01 1 Unchanged Low Q16632 116.1383 −1.11E−01 −6.14E−02 1 Unchanged Low P54762 129.1191 5.96E−02 6.48E−01 1 Unchanged Low Q15269 114.654 −1.61E−01 −2.25E−01 1 Unchanged Low O14495 113.9808 −1.10E−01 −1.44E−01 1 Unchanged Low Q9P0U0 121.9267 −4.47E−01 −5.91E−01 1 Unchanged Low P50120 187.0028 −1.05E+00 −9.36E−02 1 Unchanged Low Q9UHR0 124.9147 1.91E−03 4.33E−01 1 Unchanged Low Q13977 132.4319 9.09E−02 7.75E−01 1 Unchanged Low P51692 112.9412 −1.78E−01 −3.43E−01 1 Unchanged Low P51164 120.3347 −2.82E−01 −2.81E−01 1 Unchanged Low Q9NXH3 117.6836 −1.35E−02 1.70E−01 1 Unchanged Low 116.8658 −8.33E−03 1.51E−01 1 Unchanged Low P16435 118.227 2.71E−02 2.62E−01 1 Unchanged Low 121.7814 −4.80E−02 2.36E−01 1 Unchanged Low Q02080 117.0502 −3.03E−01 −4.69E−01 1 Unchanged Low Q15334 115.3049 −1.34E−01 −1.62E−01 1 Unchanged Low P10636 123.46 −4.39E−02 2.94E−01 1 Unchanged Low Q9Y4J6 117.8247 −3.05E−01 −4.43E−01 1 Unchanged Low Q9UHY7 118.5336 4.73E−02 3.00E−01 1 Unchanged Low Q14147 116.4348 −5.95E−02 1.76E−02 1 Unchanged Low O95880 128.5046 −5.75E−01 −6.88E−01 1 Unchanged Low Q15013 138.5918 1.13E−01 9.22E−01 1 Unchanged Low Q9P1E2 119.6869 −2.93E−01 −3.69E−01 1 Unchanged Low P07203 115.8519 −9.06E−02 −8.19E−02 1 Unchanged Low Q13206 115.4153 −3.12E−01 −6.03E−01 1 Unchanged Low O15085 115.3055 −1.05E−01 −1.37E−01 1 Unchanged Low P48426 169.6778 −1.04E+00 −5.16E−01 1 Unchanged Low Q9NRQ2 118.4782 −1.56E−01 −1.23E−01 1 Unchanged Low O43171 117.8862 −1.61E−01 −1.60E−01 1 Unchanged Low Q9HB90 127.5658 −2.29E−01 3.71E−02 1 Unchanged Low Q9H733 121.334 −8.84E−04 2.71E−01 1 Unchanged Low P43353 118.734 −3.21E−01 −4.90E−01 1 Unchanged Low Q15053 123.496 3.09E−02 3.91E−01 1 Unchanged Low P22301 132.021 −6.22E−01 −7.00E−01 1 Unchanged Low Q9BW47 131.1841 −1.47E−01 2.92E−01 1 Unchanged Low P21917 141.2355 −4.80E−01 −6.96E−02 1 Unchanged Low Q9Y6K5 127.6931 −1.59E−01 1.56E−01 1 Unchanged Low Q9Y2A4 127.5854 −2.54E−01 −3.82E−02 1 Unchanged Low Q16880 119.9407 1.56E−02 2.33E−01 1 Unchanged Low O95747 116.7318 1.08E−02 1.12E−01 1 Unchanged Low P25106 120.5368 1.82E−01 5.42E−01 1 Unchanged Low 120.6924 1.55E−01 4.98E−01 1 Unchanged Low P45984 113.914 −2.86E−01 −6.64E−01 1 Unchanged Low Q9NPF7 131.5891 2.11E−01 8.77E−01 1 Unchanged Low Q9UH94 120.3231 −2.95E−01 −4.04E−01 1 Unchanged Low Q16559 118.9991 −1.99E−01 −2.45E−01 1 Unchanged Low Q9UGH0 123.6748 2.16E−01 6.75E−01 1 Unchanged Low Q15544 118.4317 −3.46E−02 6.82E−02 1 Unchanged Low O00628 122.588 −4.45E−01 −6.89E−01 1 Unchanged Low O43241 114.422 −1.10E−01 −2.46E−01 1 Unchanged Low Q9Y6N1 114.0678 −1.46E−01 −3.44E−01 1 Unchanged Low Q9UHX5 122.8348 2.26E−01 6.60E−01 1 Unchanged Low Q01664 150.0321 −1.22E+00 −2.01E+00 1 Unchanged Low Q9BUI1 117.3611 3.55E−02 1.53E−01 1 Unchanged Low Q9HBL5 118.5457 1.46E−01 3.93E−01 1 Unchanged Low Q9NXV2 129.6462 −1.38E−01 2.16E−01 1 Unchanged Low Q15424 114.2781 −2.29E−01 −5.42E−01 1 Unchanged Low P26440 136.2534 −6.33E−01 −6.38E−01 1 Unchanged Low O60264 117.7402 1.24E−01 3.22E−01 1 Unchanged Low Q15286 145.6 −2.62E−01 4.06E−01 1 Unchanged Low Q9UGK0 196.7868 −1.39E+00 −8.21E−01 1 Unchanged Low Q92980 146.2003 −3.00E−01 3.50E−01 1 Unchanged Low Q99726 116.3247 3.39E−02 9.75E−02 1 Unchanged Low P01111 115.8629 −9.70E−02 −1.90E−01 1 Unchanged Low Q92574 117.8303 7.50E−02 2.20E−01 1 Unchanged Low P16106 122.8016 −2.20E−01 −1.98E−01 1 Unchanged Low Q9NWX5 115.5043 −2.67E−02 −7.26E−02 1 Unchanged Low Q9Y6B7 168.0108 −9.09E−01 −3.57E−01 1 Unchanged Low Q9Y4F1 118.0819 9.52E−02 2.55E−01 1 Unchanged Low Q06710 121.7641 −4.93E−02 1.03E−01 1 Unchanged Low Q9H6N1 190.8582 −8.84E−01 1.73E−01 1 Unchanged Low Q9NSY1 117.0914 5.50E−02 1.38E−01 1 Unchanged Low Q14106 122.8358 −2.11E−02 1.87E−01 1 Unchanged Low Q9UK11 122.8322 −3.47E−02 1.60E−01 1 Unchanged Low P08069 133.4883 1.29E−01 7.42E−01 1 Unchanged Low Q9H6F5 116.1638 −5.11E−02 −1.10E−01 1 Unchanged Low Q14373 168.3955 −4.39E−01 5.51E−01 1 Unchanged Low P20393 120.571 1.20E−01 3.67E−01 1 Unchanged Low P36915 116.2706 −5.41E−02 −1.18E−01 1 Unchanged Low O95109 121.0452 −3.01E−01 −4.79E−01 1 Unchanged Low Q9NVS2 119.5497 −1.67E−02 7.31E−02 1 Unchanged Low Q92950 118.6125 8.72E−02 2.34E−01 1 Unchanged Low Q14977 127.3783 1.26E−01 5.62E−01 1 Unchanged Low P16106 123.5385 3.04E−01 7.45E−01 1 Unchanged Low Q9Y3C1 141.934 −3.11E−01 1.72E−01 1 Unchanged Low P37287 119.4716 −1.77E−01 −2.87E−01 1 Unchanged Low Q9UIG5 122.443 1.94E−01 5.25E−01 1 Unchanged Low Q9UNE2 117.0111 8.86E−02 1.62E−01 1 Unchanged Low Q14123 123.5304 −4.75E−02 1.21E−01 1 Unchanged Low Q16206 130.1671 1.15E−02 4.26E−01 1 Unchanged Low Q9NWT1 116.4708 1.77E−02 −2.15E−03 1 Unchanged Low Q12756 162.7767 −2.36E−01 7.47E−01 1 Unchanged Low P28288 117.9674 −2.56E−01 −5.51E−01 1 Unchanged Low P05198 117.2266 2.59E−02 3.77E−02 1 Unchanged Low Q9H0V9 115.9248 −1.31E−01 −3.47E−01 1 Unchanged Low Q92984 198.9799 −1.13E+00 −2.23E−01 1 Unchanged Low O95498 116.8572 1.02E−01 1.64E−01 1 Unchanged Low Q9H1E1 119.4295 1.08E−01 2.62E−01 1 Unchanged Low Q9NV88 117.172 1.18E−01 2.04E−01 1 Unchanged Low Q9Y310 117.0556 −2.52E−02 −8.10E−02 1 Unchanged Low P48382 143.9771 −6.98E−01 −6.47E−01 1 Unchanged Low P52738 136.2205 −2.10E−01 1.71E−01 1 Unchanged Low Q9NRW1 132.4668 2.32E−01 8.29E−01 1 Unchanged Low O15298 165.1797 −1.18E+00 −1.27E+00 1 Unchanged Low Q9NUN5 116.1573 4.62E−02 1.41E−02 1 Unchanged Low Q07699 115.8757 2.19E−02 −4.76E−02 1 Unchanged Low P27701 114.2624 2.60E−02 −1.05E−01 1 Unchanged Low Q9UER5 118.2694 1.74E−01 3.24E−01 1 Unchanged Low Q8TAC6 124.5089 1.42E−02 2.28E−01 1 Unchanged Low Q9NRW9 120.1901 −2.03E−01 −3.76E−01 1 Unchanged Low O95147 166.9415 −6.17E−01 1.37E−01 1 Unchanged Low Q13895 116.9004 1.37E−01 1.98E−01 1 Unchanged Low P31645 140.7231 5.19E−02 7.19E−01 1 Unchanged Low P51511 122.1739 −4.82E−02 2.16E−02 1 Unchanged Low Q15154 128.7076 −1.05E−01 1.25E−01 1 Unchanged Low Q00007 116.7703 1.35E−01 1.82E−01 1 Unchanged Low P55822 128.0275 −1.46E−01 1.76E−02 1 Unchanged Low Q14442 118.0476 −2.44E−02 −8.61E−02 1 Unchanged Low P54792 119.4338 −8.94E−02 −1.70E−01 1 Unchanged Low P42336 121.01 2.37E−01 4.98E−01 1 Unchanged Low Q9UMQ3 132.6879 2.59E−01 8.49E−01 1 Unchanged Low Q9UPY5 120.9226 −5.44E−01 −1.32E+00 1 Unchanged Low P19113 116.6743 9.22E−02 8.57E−02 1 Unchanged Low O95394 118.8198 −6.50E−02 −1.52E−01 1 Unchanged Low P22557 150.2281 −7.60E−01 −6.46E−01 1 Unchanged Low Q9Y3A2 131.6512 1.36E−01 6.16E−01 1 Unchanged Low Q9H5J4 113.8461 −1.76E−01 −6.34E−01 1 Unchanged Low P16083 124.3296 −3.73E−01 −6.50E−01 1 Unchanged Low Q99819 117.2457 −7.30E−02 −2.42E−01 1 Unchanged Low O75569 118.9057 2.54E−01 4.47E−01 1 Unchanged Low O15038 113.8294 −6.45E−02 −3.74E−01 1 Unchanged Low Q9HBH5 120.3437 2.30E−01 4.48E−01 1 Unchanged Low P41231 127.3275 −1.39E−01 −1.84E−02 1 Unchanged Low O15397 117.4304 6.43E−02 3.71E−02 1 Unchanged Low Q9UDY8 118.129 6.73E−02 6.76E−02 1 Unchanged Low O95819 122.7769 3.76E−01 7.55E−01 1 Unchanged Low Q12999 114.8641 6.17E−02 −6.74E−02 1 Unchanged Low P25440 114.7701 4.08E−02 −1.16E−01 1 Unchanged Low P20827 392.8203 −1.31E+00 1.35E+00 1 Unchanged Low Q9H652 118.9065 −1.05E−01 −2.80E−01 1 Unchanged Low P31483 118.2227 1.93E−01 2.87E−01 1 Unchanged Low Q9BSM8 180.6391 −2.98E−01 8.82E−01 1 Unchanged Low P36897 114.8546 6.00E−02 −9.83E−02 1 Unchanged Low Q9UMR9 191.0958 −1.08E+00 −3.82E−01 1 Unchanged Low Q92560 127.8687 2.53E−01 6.72E−01 1 Unchanged Low Q9NWU1 124.8325 2.76E−01 6.26E−01 1 Unchanged Low Q92696 205.3234 −8.83E−01 2.91E−01 1 Unchanged Low O95236 119.1528 1.80E−01 2.87E−01 1 Unchanged Low Q13202 131.9045 −2.77E−01 −1.88E−01 1 Unchanged Low P11277 116.0084 9.99E−02 2.26E−02 1 Unchanged Low O95397 121.1071 2.77E−01 5.16E−01 1 Unchanged Low P05423 116.0734 −1.24E−01 −4.65E−01 1 Unchanged Low Q14338 133.9938 2.78E−01 8.63E−01 1 Unchanged Low Q9BYI8 125.1864 4.25E−01 8.67E−01 1 Unchanged Low Q06203 147.3953 −8.38E−01 −1.04E+00 1 Unchanged Low Q9NZ33 132.4428 8.83E−02 5.12E−01 1 Unchanged Low P04196 117.5882 6.06E−02 −7.63E−03 1 Unchanged Low O96029 138.7174 −7.31E−01 −1.11E+00 1 Unchanged Low Q01196 232.9078 −1.86E+00 −1.69E+00 1 Unchanged Low Q9UHL4 164.207 −5.72E−01 8.23E−02 1 Unchanged Low P55211 115.3899 9.62E−02 −2.94E−02 1 Unchanged Low P21283 232.7446 −1.25E+00 −1.78E−03 1 Unchanged Low O43422 117.7416 −1.19E−01 −4.00E−01 1 Unchanged Low P78406 121.9098 −2.76E−01 −5.99E−01 1 Unchanged Low P43362 119.97 2.95E−01 4.92E−01 1 Unchanged Low Q9H693 129.9396 −4.98E−01 −8.33E−01 1 Unchanged Low Q9UJ83 120.5495 2.91E−01 4.99E−01 1 Unchanged Low Q05048 117.088 −2.92E−02 −2.36E−01 1 Unchanged Low P19784 122.6579 3.63E−01 6.78E−01 1 Unchanged Low Q9BUX8 155.6701 −4.59E−01 8.56E−02 1 Unchanged Low Q9Y5P6 125.8828 −4.50E−01 −8.97E−01 1 Unchanged Low Q9Y3E1 122.172 3.30E−01 6.05E−01 1 Unchanged Low P40426 113.1427 −9.01E−03 −3.72E−01 1 Unchanged Low P11217 182.286 −1.37E+00 −1.52E+00 1 Unchanged Low Q16563 121.3173 3.23E−01 5.63E−01 1 Unchanged Low O95698 119.6732 2.57E−01 3.97E−01 1 Unchanged Low P19447 121.7269 3.56E−01 6.30E−01 1 Unchanged Low Q9UK39 185.8825 −5.09E−01 5.89E−01 1 Unchanged Low Q15785 187.6861 −1.28E+00 −1.04E+00 1 Unchanged Low Q99571 316.7241 −1.77E+00 −2.96E−02 1 Unchanged Low Q9BTY2 115.258 −1.09E−01 −5.28E−01 1 Unchanged Low Q9P0P1 153.8845 −2.72E−01 3.71E−01 1 Unchanged Low Q9Y324 116.2093 −7.52E−02 −4.13E−01 1 Unchanged Low P37286 128.7921 3.10E−01 7.38E−01 1 Unchanged Low Q00577 120.658 7.91E−02 8.84E−02 1 Unchanged Low O75152 121.2139 2.73E−01 4.61E−01 1 Unchanged Low P23610 130.3149 −4.28E−01 −6.73E−01 1 Unchanged Low O75436 116.2363 5.44E−02 −1.30E−01 1 Unchanged Low Q9HA40 117.8494 2.29E−01 2.71E−01 1 Unchanged Low Q9NX62 120.7522 2.42E−01 3.88E−01 1 Unchanged Low O76062 212.8749 −1.29E+00 −4.89E−01 1 Unchanged Low Q16445 120.3177 −2.95E−01 −7.83E−01 1 Unchanged Low Q08462 125.3933 1.92E−01 4.39E−01 1 Unchanged Low P78560 128.1152 1.80E−01 4.97E−01 1 Unchanged Low P19634 113.6214 4.65E−02 −2.66E−01 1 Unchanged Low P28370 114.9572 9.02E−02 −1.17E−01 1 Unchanged Low Q92503 141.9225 −3.02E−01 −3.46E−03 1 Unchanged Low Q9UL02 117.4294 2.19E−01 2.25E−01 1 Unchanged Low Q9Y5T5 120.0007 7.16E−02 3.32E−02 1 Unchanged Low 134.1729 −3.14E−01 −2.78E−01 1 Unchanged Low P15848 122.7499 −2.79E−01 −6.45E−01 1 Unchanged Low Q9UP66 120.4437 1.09E−01 1.17E−01 1 Unchanged Low O75160 120.8501 1.55E−02 −5.53E−02 1 Unchanged Low P78385 119.6793 2.92E−01 4.24E−01 1 Unchanged Low O94967 124.6247 4.20E−01 7.82E−01 1 Unchanged Low O95719 117.7043 1.91E−01 1.71E−01 1 Unchanged Low P48147 127.6048 −7.64E−02 −7.45E−03 1 Unchanged Low P20231 119.9323 2.11E−01 2.81E−01 1 Unchanged Low O95299 119.8634 2.03E−01 2.60E−01 1 Unchanged Low O75033 122.4835 2.48E−02 9.32E−03 1 Unchanged Low P51668 120.3 3.08E−01 4.61E−01 1 Unchanged Low P28289 233.0271 −1.30E+00 −1.62E−01 1 Unchanged Low Q15631 149.5989 −4.85E−01 −1.88E−01 1 Unchanged Low P49868 113.6937 1.76E−02 −3.63E−01 1 Unchanged Low P51959 114.0387 8.50E−02 −1.99E−01 1 Unchanged Low Q9Y5V0 139.0584 1.19E−01 6.54E−01 1 Unchanged Low P56270 170.7774 −1.00E+00 −8.26E−01 1 Unchanged Low Q9HD23 127.1502 −1.86E−01 −2.72E−01 1 Unchanged Low P78358 159.681 −8.14E−01 −6.68E−01 1 Unchanged Low O00327 142.5298 6.87E−02 6.50E−01 1 Unchanged Low Q9H969 130.1172 4.75E−01 9.89E−01 1 Unchanged Low O15504 149.5876 −6.90E−01 −6.92E−01 1 Unchanged Low P35250 115.9922 1.59E−01 1.21E−02 1 Unchanged Low Q9BXC0 118.786 2.51E−01 2.87E−01 1 Unchanged Low O15232 115.8185 1.37E−01 −4.27E−02 1 Unchanged Low O76049 198.6303 −4.66E−01 8.00E−01 1 Unchanged Low Q14145 146.2645 −6.39E−01 −6.90E−01 1 Unchanged Low P20848 127.9292 3.50E−01 7.23E−01 1 Unchanged Low Q9P0N6 115.304 1.54E−01 −3.53E−02 1 Unchanged Low P05188 125.869 4.94E−01 8.94E−01 1 Unchanged Low Q9UBJ4 117.695 −7.21E−02 −4.30E−01 1 Unchanged Low Q13876 125.9829 −2.11E−01 −4.06E−01 1 Unchanged Low Q9UBF2 116.849 1.81E−01 6.78E−02 1 Unchanged Low P43026 126.3658 2.93E−01 5.77E−01 1 Unchanged Low Q9HD20 123.6472 1.62E−01 2.67E−01 1 Unchanged Low Q96KK6 116.8445 6.05E−02 −1.80E−01 1 Unchanged Low P40617 130.7449 1.06E−02 2.04E−01 1 Unchanged Low O75651 128.2583 −7.77E−02 −4.74E−02 1 Unchanged Low Q9Y2S1 131.4839 −1.17E−01 −2.10E−02 1 Unchanged Low Q13330 116.0949 2.53E−01 1.71E−01 1 Unchanged Low Q9Y389 114.7055 1.19E−01 −1.55E−01 1 Unchanged Low O60513 115.0129 1.40E−01 −1.00E−01 1 Unchanged Low O00212 341.5178 −1.70E+00 2.70E−01 1 Unchanged Low Q9NXE1 122.4125 3.81E−01 5.97E−01 1 Unchanged Low O95405 154.2554 1.38E−01 9.72E−01 1 Unchanged Low P01112 119.6125 −4.91E−02 −3.23E−01 1 Unchanged Low O15120 209.3705 −1.08E+00 −1.49E−01 1 Unchanged Low P12645 116.6372 2.20E−01 1.18E−01 1 Unchanged Low P50579 121.7158 −2.05E−01 −6.04E−01 1 Unchanged Low O14908 176.6683 −7.04E−01 −3.26E−02 1 Unchanged Low Q9HCC6 140.2118 6.13E−01 1.38E+00 1 Unchanged Low Q15737 125.8246 1.62E−01 3.14E−01 1 Unchanged Low Q9Y519 119.1056 3.24E−01 3.87E−01 1 Unchanged Low Q9Y5J0 116.7986 9.99E−02 −1.33E−01 1 Unchanged Low P51687 119.5637 2.59E−01 2.77E−01 1 Unchanged Low P51178 138.0904 −4.43E−03 3.56E−01 1 Unchanged Low Q9H8J6 148.4766 5.05E−02 7.00E−01 1 Unchanged Low O95900 182.738 −3.94E−01 6.31E−01 1 Unchanged Low Q9Y6N3 120.3564 3.37E−01 4.35E−01 1 Unchanged Low Q07869 119.4872 7.16E−02 −9.89E−02 1 Unchanged Low Q9Y333 116.4501 2.11E−01 6.39E−02 1 Unchanged Low Q9NPD1 205.7432 −7.07E−01 4.67E−01 1 Unchanged Low Q15928 138.6304 3.20E−01 8.98E−01 1 Unchanged Low O43826 155.5451 −8.63E−01 −1.05E+00 1 Unchanged Low Q9NWL0 120.1186 1.48E−01 7.25E−02 1 Unchanged Low P31629 151.1911 1.24E−01 8.64E−01 1 Unchanged Low O15530 168.488 −5.58E−01 5.15E−02 1 Unchanged Low Q9Y2R5 122.8701 2.50E−01 3.52E−01 1 Unchanged Low Q15208 163.2891 −3.28E−01 3.64E−01 1 Unchanged Low Q9UET6 116.4386 3.04E−01 2.30E−01 1 Unchanged Low Q9H5N0 119.1911 3.07E−01 3.30E−01 1 Unchanged Low Q9H019 126.5367 3.04E−01 5.53E−01 1 Unchanged Low Q9Y673 119.1797 3.38E−01 3.81E−01 1 Unchanged Low O75690 132.5659 6.31E−02 3.01E−01 1 Unchanged Low Q9NUP6 122.1684 4.03E−01 5.84E−01 1 Unchanged Low Q14296 114.1093 5.10E−02 −3.98E−01 1 Unchanged Low Q9NW55 120.8058 4.23E−01 5.70E−01 1 Unchanged Low O43639 115.5457 −1.40E−01 −8.13E−01 1 Unchanged Low P17544 115.9726 2.27E−01 4.79E−02 1 Unchanged Low O75911 152.0313 −2.99E−01 1.43E−01 1 Unchanged Low Q06430 120.315 4.27E−01 5.58E−01 1 Unchanged Low Q13769 123.5081 5.05E−02 −2.60E−02 1 Unchanged Low Q9H864 122.387 3.82E−01 5.45E−01 1 Unchanged Low O95500 163.6478 −5.24E−01 −1.90E−02 1 Unchanged Low P14222 120.5243 3.62E−01 4.47E−01 1 Unchanged Low Q9Y4C8 126.2296 2.72E−01 4.67E−01 1 Unchanged Low Q9H3H5 143.2265 −6.04E−01 −8.39E−01 1 Unchanged Low Q13433 116.7563 1.12E−01 −1.76E−01 1 Unchanged Low Q00059 123.3486 1.96E−01 2.32E−01 1 Unchanged Low Q15119 120.0132 3.96E−01 4.81E−01 1 Unchanged Low O43791 117.7111 1.98E−01 3.49E−02 1 Unchanged Low Q14206 170.2393 9.21E−02 1.14E+00 1 Unchanged Low Q92926 116.1179 1.50E−01 −1.27E−01 1 Unchanged Low Q9P288 136.3262 −2.20E−01 −1.72E−01 1 Unchanged Low Q9NZU5 139.9549 −3.60E−01 −3.61E−01 1 Unchanged Low Q13569 127.6936 6.22E−01 1.05E+00 1 Unchanged Low P48167 125.3664 2.24E−01 3.39E−01 1 Unchanged Low Q9NQR1 124.9651 −2.69E−01 −7.35E−01 1 Unchanged Low O43405 117.417 3.14E−01 2.31E−01 1 Unchanged Low Q9P028 121.9053 3.01E−01 3.59E−01 1 Unchanged Low Q9Y6E8 115.6628 2.32E−01 5.37E−03 1 Unchanged Low Q9NV65 136.3658 4.75E−01 1.03E+00 1 Unchanged Low Q9H0R8 143.1503 7.20E−02 5.52E−01 1 Unchanged Low O95817 116.5745 2.61E−01 9.05E−02 1 Unchanged Low P36956 125.9988 −1.26E−01 −3.60E−01 1 Unchanged Low P08236 122.0379 5.60E−02 −1.21E−01 1 Unchanged Low Q13425 119.2218 2.70E−01 1.96E−01 1 Unchanged Low Q14676 122.2375 4.63E−01 6.30E−01 1 Unchanged Low P16106 120.7804 3.94E−01 4.68E−01 1 Unchanged Low Q14773 122.427 3.39E−01 4.24E−01 1 Unchanged Low O14736 126.6152 4.48E−02 1.47E−02 1 Unchanged Low Q9Y297 141.0555 −2.41E−01 −1.01E−01 1 Unchanged Low Q13585 121.1757 7.99E−02 −1.14E−01 1 Unchanged Low O60858 116.2529 2.27E−01 −6.09E−03 1 Unchanged Low Q9Y2Z6 121.3443 4.22E−01 5.29E−01 1 Unchanged Low Q9UG66 273.7118 −1.30E+00 2.32E−01 1 Unchanged Low Q9Y6G5 125.8408 2.61E−01 3.83E−01 1 Unchanged Low P98155 115.483 1.91E−01 −1.19E−01 1 Unchanged Low Q9NP50 140.8474 4.50E−01 1.07E+00 1 Unchanged Low P28328 223.2274 −1.31E+00 −5.56E−01 1 Unchanged Low Q969T4 115.6428 1.42E−01 −2.24E−01 1 Unchanged Low P19827 185.0551 −8.88E−01 −3.62E−01 1 Unchanged Low O15096 120.4316 1.43E−01 −3.31E−02 1 Unchanged Low Q9Y5J6 119.4401 3.39E−01 3.06E−01 1 Unchanged Low Q92889 128.238 −2.83E−01 −6.91E−01 1 Unchanged Low P08697 134.8048 −9.67E−02 −2.29E−02 1 Unchanged Low Q9UBX1 120.4495 1.93E−01 6.08E−02 1 Unchanged Low Q9NPI7 180.4148 −8.90E−01 −4.93E−01 1 Unchanged Low P11586 125.7751 −1.21E−01 −4.11E−01 1 Unchanged Low O96010 125.1912 5.14E−01 7.67E−01 1 Unchanged Low Q13188 127.4091 1.45E−01 1.99E−01 1 Unchanged Low Q13845 121.3988 −1.68E−01 −7.24E−01 1 Unchanged Low Q9Y5W9 157.7019 −1.54E−01 4.56E−01 1 Unchanged Low O60539 119.7412 3.58E−02 −3.10E−01 1 Unchanged Low O60885 114.4111 1.78E−01 −2.29E−01 1 Unchanged Low Q9H2B0 133.1825 8.60E−02 2.61E−01 1 Unchanged Low P51582 118.649 1.61E−01 −9.03E−02 1 Unchanged Low O00585 171.5056 −3.74E−01 3.53E−01 1 Unchanged Low Q15131 135.7223 −3.73E−01 −6.38E−01 1 Unchanged Low O75148 129.5265 5.97E−01 9.99E−01 1 Unchanged Low Q15691 157.4437 −4.15E−01 −4.51E−02 1 Unchanged Low Q15779 135.0227 −1.18E−01 −8.51E−02 1 Unchanged Low Q9UHD2 128.1679 6.62E−01 1.06E+00 1 Unchanged Low Q9NSS3 117.5518 2.77E−01 9.44E−02 1 Unchanged Low Q13797 124.1726 −2.67E−01 −8.84E−01 1 Unchanged Low P46531 126.8111 6.01E−01 9.30E−01 1 Unchanged Low O43262 134.2594 7.65E−01 1.35E+00 1 Unchanged Low Q9Y2H6 142.9858 −3.89E−01 −4.22E−01 1 Unchanged Low P25788 224.7239 −9.86E−01 1.40E−01 1 Unchanged Low Q9BQS8 167.5571 −3.34E−01 3.33E−01 1 Unchanged Low Q9Y396 125.1558 −3.16E−01 −9.85E−01 1 Unchanged Low Q9P0R7 158.5209 4.43E−02 7.84E−01 1 Unchanged Low O15269 120.3129 4.24E−01 4.46E−01 1 Unchanged Low Q9UFX0 217.1357 −8.35E−01 2.98E−01 1 Unchanged Low Q9H663 119.1698 4.15E−01 3.87E−01 1 Unchanged Low O75410 162.703 −7.75E−01 −7.53E−01 1 Unchanged Low Q9Y5N5 121.2285 4.00E−01 4.24E−01 1 Unchanged Low Q9BQ72 117.4135 3.02E−01 1.09E−01 1 Unchanged Low Q9Y303 128.5162 −2.27E−01 −6.08E−01 1 Unchanged Low Q9P005 350.7027 −1.38E+00 7.64E−01 1 Unchanged Low Q9Y3A1 198.1031 −6.08E−01 3.88E−01 1 Unchanged Low Q15172 146.553 −3.56E−01 −2.69E−01 1 Unchanged Low Q9BV19 122.8739 4.48E−01 5.43E−01 1 Unchanged Low Q14534 119.574 −2.39E−01 −1.13E+00 1 Unchanged Low Q9BS43 281.8569 −2.17E+00 −2.29E+00 1 Unchanged Low P49788 121.3412 4.41E−01 4.73E−01 1 Unchanged Low Q9UP83 124.3058 3.96E−01 4.89E−01 1 Unchanged Low Q9Y2X0 115.5741 1.75E−01 −2.56E−01 1 Unchanged Low Q9Y3E3 119.5355 4.78E−01 4.76E−01 1 Unchanged Low O95183 126.6473 5.34E−01 7.81E−01 1 Unchanged Low Q13242 143.0016 −2.41E−01 −1.48E−01 1 Unchanged Low Q9Y5R5 131.5571 3.90E−01 6.81E−01 1 Unchanged Low P04181 116.724 2.34E−01 −8.99E−02 1 Unchanged Low Q14254 138.6301 2.25E−02 2.38E−01 1 Unchanged Low Q9Y6E6 121.0265 4.86E−01 5.31E−01 1 Unchanged Low Q9H237 179.3923 −1.64E−01 7.98E−01 1 Unchanged Low Q92785 119.7533 1.61E−01 −1.26E−01 1 Unchanged Low O95458 120.4814 3.89E−02 −3.67E−01 1 Unchanged Low P20749 194.2507 −9.95E−01 −5.05E−01 1 Unchanged Low Q9H2N8 132.1507 3.45E−01 6.14E−01 1 Unchanged Low Q15020 132.2727 1.77E−01 3.26E−01 1 Unchanged Low P42025 156.1129 −8.79E−01 −1.41E+00 1 Unchanged Low P98173 120.727 2.31E−01 4.31E−02 1 Unchanged Low O95295 192.0882 −1.29E+00 −1.44E+00 1 Unchanged Low Q9NVA1 114.8529 2.48E−01 −1.59E−01 1 Unchanged Low P35573 116.8065 2.46E−01 −8.27E−02 1 Unchanged Low Q13126 190.4847 −6.10E−01 2.17E−01 1 Unchanged Low P43034 121.4511 3.16E−01 2.22E−01 1 Unchanged Low Q01844 115.5021 2.57E−01 −1.22E−01 1 Unchanged Low P27482 117.2725 2.14E−01 −1.40E−01 1 Unchanged Low Q9NUW4 144.6673 −7.51E−01 −1.54E+00 1 Unchanged Low P78552 115.0749 1.70E−01 −3.33E−01 1 Unchanged Low P51843 116.7757 3.46E−01 1.03E−01 1 Unchanged Low P15822 125.3978 6.78E−01 9.40E−01 1 Unchanged Low Q9BXY9 121.2561 5.53E−01 6.20E−01 1 Unchanged Low Q9ULB4 181.8847 −1.04E+00 −1.01E+00 1 Unchanged Low Q9NZZ7 204.594 −6.87E−01 3.04E−01 1 Unchanged Low Q02086 122.3826 4.02E−01 3.90E−01 1 Unchanged Low Q9BUV9 118.2651 3.88E−01 2.22E−01 1 Unchanged Low Q9UHJ9 118.5627 4.07E−01 2.67E−01 1 Unchanged Low Q16401 132.2946 −1.04E−01 −2.63E−01 1 Unchanged Low Q9Y4K4 141.2069 1.37E−02 2.51E−01 1 Unchanged Low O60463 129.2479 3.73E−01 5.47E−01 1 Unchanged Low O95639 128.1539 −4.54E−01 −1.44E+00 1 Unchanged Low P50539 165.4016 −3.93E−01 8.87E−02 1 Unchanged Low Q9UH62 140.9912 1.77E−01 5.32E−01 1 Unchanged Low O15525 116.1167 3.45E−01 5.31E−02 1 Unchanged Low Q9H8T0 160.2791 3.33E−01 1.18E+00 1 Unchanged Low Q9Y4X5 120.4976 4.29E−01 3.66E−01 1 Unchanged Low Q9H9E1 128.4841 −3.65E−01 −1.13E+00 1 Unchanged Low Q93063 139.4501 1.24E−01 3.82E−01 1 Unchanged Low Q9H992 124.4411 5.87E−01 7.37E−01 1 Unchanged Low O43237 181.4903 −1.11E+00 −1.28E+00 1 Unchanged Low Q99643 134.443 −9.24E−02 −1.95E−01 1 Unchanged Low P24386 119.0446 5.20E−01 4.56E−01 1 Unchanged Low Q9Y5F7 116.632 4.03E−01 1.58E−01 1 Unchanged Low P06756 184.6891 −5.72E−01 1.33E−01 1 Unchanged Low Q9H5L7 152.0822 −3.68E−01 −2.34E−01 1 Unchanged Low O15517 144.7566 5.44E−01 1.17E+00 1 Unchanged Low Q9P0N5 123.7736 3.18E−01 2.53E−01 1 Unchanged Low Q9NWT2 115.8334 3.20E−01 −4.05E−02 1 Unchanged Low Q9Y2A0 116.8334 8.19E−02 −5.30E−01 1 Unchanged Low Q9NZ43 137.7883 −6.58E−02 −4.24E−02 1 Unchanged Low P27986 119.3503 2.77E−01 4.28E−03 1 Unchanged Low Q9UBP6 121.358 3.32E−01 1.85E−01 1 Unchanged Low Q9BWK5 119.8654 4.17E−01 2.88E−01 1 Unchanged Low P54802 135.7965 −6.09E−01 −1.64E+00 1 Unchanged Low O75963 143.3711 2.94E−01 7.40E−01 1 Unchanged Low Q9NXZ4 121.5448 1.21E−01 −2.50E−01 1 Unchanged Low O60353 122.5147 6.62E−01 7.73E−01 1 Unchanged Low Q9NQS6 130.917 5.25E−01 7.90E−01 1 Unchanged Low O14776 122.1137 2.59E−01 4.90E−02 1 Unchanged Low Q9Y5A2 158.5684 −1.83E−01 2.71E−01 1 Unchanged Low P49842 146.5953 2.52E−02 3.56E−01 1 Unchanged Low Q06546 120.885 6.10E−01 6.34E−01 1 Unchanged Low Q9Y2E7 116.739 3.06E−01 −7.00E−02 1 Unchanged Low Q9UM11 134.12 7.50E−01 1.20E+00 1 Unchanged Low Q99447 129.39 −3.62E−01 −1.18E+00 1 Unchanged Low Q9H1R3 119.5324 5.40E−01 4.63E−01 1 Unchanged Low P28358 115.6766 3.21E−01 −9.71E−02 1 Unchanged Low O76070 134.744 8.30E−02 1.18E−01 1 Unchanged Low Q9Y5A7 149.951 1.95E−01 7.08E−01 1 Unchanged Low Q9NWY7 116.6328 3.94E−01 8.20E−02 1 Unchanged Low O43715 127.9562 −1.23E−02 −3.20E−01 1 Unchanged Low Q9BY75 127.3323 2.03E−01 9.81E−02 1 Unchanged Low O43431 144.6131 1.11E−01 4.34E−01 1 Unchanged Low O43567 133.3964 3.06E−01 4.72E−01 1 Unchanged Low Q9Y2S7 117.8414 2.73E−01 −1.26E−01 1 Unchanged Low O14582 135.7349 1.66E−02 1.46E−03 1 Unchanged Low O75056 139.562 1.88E−01 4.31E−01 1 Unchanged Low Q9P2Y2 123.2251 6.09E−01 6.75E−01 1 Unchanged Low Q16595 135.5917 −2.85E−02 −9.82E−02 1 Unchanged Low Q14807 115.2048 2.58E−01 −2.81E−01 1 Unchanged Low Q9BZL4 123.5234 3.10E−01 1.54E−01 1 Unchanged Low P30876 200.7168 −9.54E−01 −4.12E−01 1 Unchanged Low Q9UGP6 122.0845 5.35E−01 5.02E−01 1 Unchanged Low P52655 129.1154 1.77E−01 8.08E−02 1 Unchanged Low Q9HB07 125.5248 1.81E−01 −4.11E−02 1 Unchanged Low Q92940 258.3032 −1.59E+00 −8.95E−01 1 Unchanged Low Q9NWN1 124.9938 2.25E−01 2.24E−02 1 Unchanged Low O43664 116.0604 3.49E−01 −7.90E−02 1 Unchanged Low O14647 132.5407 5.19E−01 7.68E−01 1 Unchanged Low O75333 130.9257 1.29E−01 3.38E−02 1 Unchanged Low Q16539 168.4312 −1.10E−01 5.57E−01 1 Unchanged Low Q9NQG5 122.4598 6.67E−01 7.18E−01 1 Unchanged Low Q15149 115.8848 1.35E−01 −5.84E−01 1 Unchanged Low Q9NVZ7 159.6342 −2.67E−01 7.06E−02 1 Unchanged Low Q15800 127.0641 −3.15E−01 −1.27E+00 1 Unchanged Low Q9H0B6 121.3672 5.17E−01 4.22E−01 1 Unchanged Low P09001 120.1502 5.53E−01 4.44E−01 1 Unchanged Low O00301 117.5428 1.34E−01 −5.14E−01 1 Unchanged Low P55786 170.346 −9.84E−01 −1.47E+00 1 Unchanged Low Q9Y5Y9 134.9928 1.20E−01 1.28E−01 1 Unchanged Low P19235 138.1099 −5.20E−01 −1.36E+00 1 Unchanged Low O15228 183.349 −7.01E−01 −2.72E−01 1 Unchanged Low Q9UK97 131.097 −1.25E−01 −5.43E−01 1 Unchanged Low P50990 197.1593 −9.88E−01 −6.28E−01 1 Unchanged Low Q9NZM1 186.4122 −6.59E−01 −1.17E−01 1 Unchanged Low Q92924 117.704 7.37E−02 −6.73E−01 1 Unchanged Low O75845 131.1196 4.45E−01 5.83E−01 1 Unchanged Low Q9NQ88 125.605 7.91E−01 9.75E−01 1 Unchanged Low Q16515 116.6136 4.45E−01 9.06E−02 1 Unchanged Low P49759 124.2553 6.90E−01 7.73E−01 1 Unchanged Low P33552 114.8881 3.45E−01 −1.91E−01 1 Unchanged Low O75808 117.8898 2.67E−01 −2.26E−01 1 Unchanged Low Q9NXR1 119.5057 5.33E−01 3.56E−01 1 Unchanged Low O75381 241.8793 −1.77E+00 −2.07E+00 1 Unchanged Low O60930 139.1464 −2.65E−01 −5.95E−01 1 Unchanged Low O14653 114.9152 2.66E−01 −3.68E−01 1 Unchanged Low Q16540 156.1365 −5.87E−01 −8.04E−01 1 Unchanged Low O14658 154.6374 −1.83E−01 7.29E−02 1 Unchanged Low Q15814 118.2869 4.34E−01 1.14E−01 1 Unchanged Low Q9Y3C9 128.8568 7.42E−01 9.69E−01 1 Unchanged Low P18827 115.5895 2.88E−01 −3.03E−01 1 Unchanged Low P04150 116.6017 3.89E−01 −4.49E−02 1 Unchanged Low Q9Y301 116.3594 3.71E−01 −9.27E−02 1 Unchanged Low O00626 119.8588 3.01E−01 −9.45E−02 1 Unchanged Low 127.048 3.72E−01 2.98E−01 1 Unchanged Low Q9Y311 125.8788 −2.18E−01 −1.12E+00 1 Unchanged Low Q15633 144.9588 −2.75E−01 −4.33E−01 1 Unchanged Low P02278 152.2309 4.82E−01 1.11E+00 1 Unchanged Low P53672 142.8494 4.64E−01 8.75E−01 1 Unchanged Low P09417 142.5395 1.48E−01 3.43E−01 1 Unchanged Low Q9HAY2 120.9341 5.48E−01 3.97E−01 1 Unchanged Low P30273 133.3475 6.67E−01 9.51E−01 1 Unchanged Low Q92949 185.89 −6.34E−01 −5.87E−01 1 Unchanged Low Q9GZT9 117.5626 3.18E−01 −1.85E−01 1 Unchanged Low P35658 139.8811 −1.07E−02 −4.96E−02 1 Unchanged Low Q9HB40 115.3964 4.12E−01 −9.32E−02 1 Unchanged Low O14686 138.5398 2.60E−01 4.11E−01 1 Unchanged Low Q92911 176.594 −9.05E−01 −1.08E+00 1 Unchanged Low Q9Y5E4 127.9379 5.70E−01 6.34E−01 1 Unchanged Low Q13057 151.0906 −4.04E−01 −5.78E−01 1 Unchanged Low Q14863 115.7954 4.53E−01 −4.97E−03 1 Unchanged Low P36610 129.0874 3.60E−01 2.98E−01 1 Unchanged Low O60240 438.2653 −2.99E+00 −4.43E+00 1 Unchanged Low Q9H9B4 120.8973 6.87E−01 5.96E−01 1 Unchanged Low O00584 172.0542 1.85E−01 1.00E+00 1 Unchanged Low Q9H658 171.1973 −1.58E−01 4.32E−01 1 Unchanged Low P18858 120.8853 6.20E−01 4.76E−01 1 Unchanged Low Q02877 295.8854 −1.66E+00 −5.99E−01 1 Unchanged Low P15586 174.2861 −8.81E−01 −1.13E+00 1 Unchanged Low P42696 161.4649 3.56E−01 1.06E+00 1 Unchanged Low O75710 116.2449 4.32E−01 −5.47E−02 1 Unchanged Low Q9NPI8 183.3737 −4.48E−01 1.45E−01 1 Unchanged Low Q9HAR6 152.8734 2.56E−01 7.32E−01 1 Unchanged Low P15018 235.0602 −8.35E−01 2.84E−01 1 Unchanged Low Q13546 137.7012 2.63E−02 −9.15E−02 1 Unchanged Low P24298 149.9584 −5.64E−01 −1.12E+00 1 Unchanged Low Q14129 131.8973 3.45E−01 3.32E−01 1 Unchanged Low Q9BQA2 164.7437 −2.12E−01 1.80E−01 1 Unchanged Low Q9UJX9 120.9085 2.27E−01 −3.06E−01 1 Unchanged Low Q99590 190.7413 −6.97E−01 −2.18E−01 1 Unchanged Low O14798 166.073 −1.68E−03 5.78E−01 1 Unchanged Low P32238 265.9537 −1.77E+00 −1.54E+00 1 Unchanged Low Q9UQ90 129.9052 4.94E−01 5.26E−01 1 Unchanged Low P82980 115.9454 3.60E−01 −2.44E−01 1 Unchanged Low P49716 128.4871 −2.44E−01 −1.20E+00 1 Unchanged Low P20062 136.6279 1.85E−01 1.71E−01 1 Unchanged Low P21580 245.0939 −9.49E−01 1.99E−01 1 Unchanged Low Q99774 170.7835 −4.52E−01 −1.76E−01 1 Unchanged Low Q9P0T1 116.1881 4.56E−01 −5.00E−02 1 Unchanged Low P06737 122.6343 7.51E−01 7.12E−01 1 Unchanged Low O15063 145.705 −6.52E−02 −5.91E−02 1 Unchanged Low P02743 115.3343 4.08E−01 −1.90E−01 1 Unchanged Low Q9NVT0 129.6057 7.10E−02 −3.23E−01 1 Unchanged Low Q9Y4P3 119.7013 3.56E−01 −1.14E−01 1 Unchanged Low Q13886 132.2194 −1.96E−01 −8.90E−01 1 Unchanged Low Q9NVP8 117.1232 4.96E−01 5.83E−02 1 Unchanged Low P08240 144.5673 −1.40E−01 −2.66E−01 1 Unchanged Low P49459 137.6267 5.43E−01 7.89E−01 1 Unchanged Low Q9NVAB 127.9498 3.52E−01 1.78E−01 1 Unchanged Low P25325 235.1972 −1.00E+00 −7.45E−02 1 Unchanged Low Q9UHI6 162.7208 8.43E−02 6.21E−01 1 Unchanged Low P52298 157.996 5.06E−02 4.61E−01 1 Unchanged Low Q9NQ30 123.2921 4.67E−01 2.24E−01 1 Unchanged Low O00541 176.2086 −3.24E−01 1.78E−01 1 Unchanged Low Q9H2V9 162.3327 −2.68E−01 −3.56E−02 1 Unchanged Low Q9NNX1 155.2699 −2.90E−02 2.49E−01 1 Unchanged Low Q13508 118.095 3.98E−01 −1.19E−01 1 Unchanged Low Q9NR30 128.2929 3.85E−01 2.36E−01 1 Unchanged Low Q14320 141.6929 4.93E−01 7.99E−01 1 Unchanged Low Q04726 156.9544 −5.54E−01 −8.86E−01 1 Unchanged Low P20061 115.787 3.00E−01 −4.56E−01 1 Unchanged Low Q9Y2Y1 147.7222 −8.89E−02 −8.58E−02 1 Unchanged Low P35754 145.4287 −8.79E−02 −1.59E−01 1 Unchanged Low Q02978 116.628 4.38E−01 −1.22E−01 1 Unchanged Low O95792 140.5872 1.48E−01 1.63E−01 1 Unchanged Low Q13232 130.592 6.74E−01 7.82E−01 1 Unchanged Low Q9NVH2 117.932 3.01E−01 −3.68E−01 1 Unchanged Low Q15561 183.8604 −6.89E−01 −4.46E−01 1 Unchanged Low Q9UPN9 130.2668 3.90E−01 2.78E−01 1 Unchanged Low Q14353 119.1987 4.14E−01 −8.24E−02 1 Unchanged Low Q9NZM5 139.1802 −4.40E−02 −3.01E−01 1 Unchanged Low O43255 120.4593 3.46E−01 −1.81E−01 1 Unchanged Low Q14331 161.7807 −1.72E−01 9.77E−02 1 Unchanged Low P18847 142.5299 1.92E−01 2.75E−01 1 Unchanged Low O60258 176.0472 −1.33E−01 4.79E−01 1 Unchanged Low P47929 129.8767 −5.31E−02 −7.04E−01 1 Unchanged Low P35227 135.0089 4.30E−01 4.80E−01 1 Unchanged Low Q15599 131.8082 −2.11E−01 −1.07E+00 1 Unchanged Low Q9UKJ5 178.8637 −3.37E−01 1.60E−01 1 Unchanged Low Q9HCB9 122.1779 6.34E−01 4.22E−01 1 Unchanged Low Q9Y3A0 147.7783 2.95E−01 5.80E−01 1 Unchanged Low P49815 138.4231 4.64E−01 6.20E−01 1 Unchanged Low P25116 123.8585 8.27E−01 7.92E−01 1 Unchanged Low O75829 128.9495 2.67E−01 −3.81E−02 1 Unchanged Low Q9NYI1 122.8588 3.91E−01 −2.14E−02 1 Unchanged Low P24347 126.9018 5.88E−01 4.84E−01 1 Unchanged Low O43189 120.038 3.88E−01 −1.46E−01 1 Unchanged Low Q9P029 168.9188 −4.56E−01 −3.41E−01 1 Unchanged Low Q9NZP9 136.3041 4.81E−01 5.78E−01 1 Unchanged Low Q9UIA3 153.0756 −1.74E−01 −1.74E−01 1 Unchanged Low Q99734 210.2011 −5.84E−01 2.56E−01 1 Unchanged Low O00411 124.1084 2.87E−01 −2.02E−01 1 Unchanged Low P28347 183.776 −6.46E−01 −4.04E−01 1 Unchanged Low Q13619 172.6621 −5.72E−02 5.07E−01 1 Unchanged Low O94929 118.4779 4.37E−01 −1.31E−01 1 Unchanged Low Q9P026 149.0331 3.51E−01 6.74E−01 1 Unchanged Low P28067 125.4983 1.96E−01 −3.58E−01 1 Unchanged Low Q14126 313.3393 −1.53E+00 −2.23E−01 1 Unchanged Low Q14267 124.7021 2.06E−01 −3.70E−01 1 Unchanged Low P55197 164.3164 −1.24E−01 2.02E−01 1 Unchanged Low Q9NP87 116.4497 3.57E−01 −4.10E−01 1 Unchanged Low P04155 180.4791 −8.07E−01 −9.25E−01 1 Unchanged Low Q9C069 207.9658 1.49E+00 3.01E+00 1 Unchanged Low P12270 129.4065 5.00E−01 3.81E−01 1 Unchanged Low Q9UIG6 230.2685 −5.62E−01 5.72E−01 1 Unchanged Low O15453 118.2765 5.78E−01 1.22E−01 1 Unchanged Low Q9UNW8 244.7569 −6.93E−01 5.36E−01 1 Unchanged Low P06746 171.8166 5.50E−02 6.58E−01 1 Unchanged Low O15414 159.7305 1.70E−01 6.00E−01 1 Unchanged Low O15259 124.437 3.67E−01 −6.59E−02 1 Unchanged Low Q9NRA8 144.3142 4.81E−01 7.45E−01 1 Unchanged Low Q9NP77 165.0639 −2.05E−01 3.60E−02 1 Unchanged Low Q06587 131.6381 3.18E−01 9.12E−02 1 Unchanged Low Q9Y5Z5 175.2357 −2.84E−01 1.13E−01 1 Unchanged Low O15327 154.5722 −3.04E−01 −4.85E−01 1 Unchanged Low P49646 136.7074 4.83E−02 −2.95E−01 1 Unchanged Low Q99809 124.7728 1.53E−01 −5.53E−01 1 Unchanged Low Q9UBM1 136.3565 1.06E−01 −1.88E−01 1 Unchanged Low P16403 377.9287 −1.52E+00 3.84E−01 1 Unchanged Low O75503 124.5021 1.33E−03 −9.83E−01 1 Unchanged Low P15814 123.9169 9.19E−01 8.64E−01 1 Unchanged Low Q03164 129.4559 −7.26E−02 −9.39E−01 1 Unchanged Low Q13624 138.6386 1.32E−01 −6.85E−02 1 Unchanged Low Q14118 118.1383 5.00E−01 −9.59E−02 1 Unchanged Low Q13286 230.6187 −6.85E−01 3.27E−01 1 Unchanged Low Q9Y5Q0 127.2281 3.55E−01 −2.72E−02 1 Unchanged Low Q9P0R1 120.8481 5.95E−01 1.96E−01 1 Unchanged Low P41182 117.2275 3.70E−01 −4.34E−01 1 Unchanged Low O75497 153.0143 4.04E−02 1.64E−01 1 Unchanged Low Q14185 118.9819 6.54E−01 2.27E−01 1 Unchanged Low O95163 157.6357 −4.36E−01 −7.60E−01 1 Unchanged Low Q14508 151.3745 5.49E−01 9.73E−01 1 Unchanged Low P25942 166.2403 4.47E−01 1.12E+00 1 Unchanged Low Q9Y6E0 194.1145 −4.60E−01 1.25E−01 1 Unchanged Low Q9UQF2 187.4786 −6.13E−01 −3.36E−01 1 Unchanged Low Q9Y285 158.2291 −2.58E−01 −3.14E−01 1 Unchanged Low Q04762 153.4581 1.65E−01 3.90E−01 1 Unchanged Low Q9Y6J9 128.6968 9.55E−01 1.03E+00 1 Unchanged Low O43913 155.6272 2.48E−02 1.88E−01 1 Unchanged Low P25208 131.7807 4.99E−01 3.77E−01 1 Unchanged Low Q9H9X4 173.1977 −3.32E−01 −7.94E−02 1 Unchanged Low O95297 133.0095 2.42E−01 −7.72E−02 1 Unchanged Low Q9UPG8 150.4388 1.62E−01 2.95E−01 1 Unchanged Low P16333 246.4108 −6.52E−01 5.66E−01 1 Unchanged Low Q14108 148.3416 −3.98E−02 −1.61E−01 1 Unchanged Low Q9UFF9 174.1041 −1.09E−01 3.55E−01 1 Unchanged Low O15242 186.2788 −4.75E−01 −8.72E−02 1 Unchanged Low Q13442 165.0545 −4.70E−02 2.67E−01 1 Unchanged Low Q99755 136.4804 4.32E−01 3.78E−01 1 Unchanged Low Q9NZV1 121.0073 4.27E−01 −1.85E−01 1 Unchanged Low Q05195 180.6838 1.47E−01 8.89E−01 1 Unchanged Low O95671 116.6189 6.06E−01 −1.74E−02 1 Unchanged Low Q9Y658 120.0494 4.27E−01 −2.46E−01 1 Unchanged Low Q9BTU6 142.5367 6.43E−01 8.74E−01 1 Unchanged Low Q9UPN6 130.9048 2.52E−01 −1.76E−01 1 Unchanged Low O00170 310.1793 −1.87E+00 −1.31E+00 1 Unchanged Low Q9UJW6 186.4423 −5.44E−01 −2.60E−01 1 Unchanged Low Q9HCT0 145.1536 −5.16E−02 −3.30E−01 1 Unchanged Low Q15459 153.5048 −1.01E−01 −1.76E−01 1 Unchanged Low O95400 194.1745 −3.34E−01 3.07E−01 1 Unchanged Low P07954 138.7259 3.31E−01 2.31E−01 1 Unchanged Low Q9H6Z5 135.2933 5.94E−01 5.88E−01 1 Unchanged Low Q9HCN8 139.1775 1.63E−01 −9.27E−02 1 Unchanged Low Q92890 176.6159 −4.00E−02 4.82E−01 1 Unchanged Low O43324 138.6164 2.17E−02 −4.25E−01 1 Unchanged Low Q9NVU8 139.1241 7.28E−02 −2.90E−01 1 Unchanged Low Q9NQW6 117.4953 4.26E−01 −4.11E−01 1 Unchanged Low Q9NWH4 144.3461 −1.80E−01 −7.03E−01 1 Unchanged Low Q9UBV8 148.3188 4.84E−02 −4.15E−02 1 Unchanged Low P15328 142.7655 5.77E−03 −3.14E−01 1 Unchanged Low Q9Y583 157.8847 9.38E−02 2.99E−01 1 Unchanged Low Q07326 126.3257 2.09E−01 −5.12E−01 1 Unchanged Low O75396 150.1024 9.19E−02 8.88E−02 1 Unchanged Low Q9Y2Z8 126.8764 3.88E−01 −9.52E−02 1 Unchanged Low Q9H3P7 220.9899 −7.10E−01 3.73E−02 1 Unchanged Low O95678 229.3684 −1.14E+00 −8.00E−01 1 Unchanged Low P17026 131.6407 1.08E−02 −7.90E−01 1 Unchanged Low Q9Y3N9 139.4653 2.75E−01 1.09E−01 1 Unchanged Low Q9BYT8 144.2719 8.41E−01 1.16E+00 1 Unchanged Low Q9UHQ7 136.5651 3.69E−01 1.95E−01 1 Unchanged Low O60921 169.0172 5.29E−02 4.60E−01 1 Unchanged Low O00400 158.3654 −3.53E−01 −6.68E−01 1 Unchanged Low Q9Y690 222.1522 −7.15E−01 3.23E−02 1 Unchanged Low Q9NZL9 127.4733 2.65E−01 −3.65E−01 1 Unchanged Low O60563 168.3854 −2.19E−01 −6.81E−02 1 Unchanged Low P20591 495.4752 −1.57E+00 9.27E−01 1 Unchanged Low Q9BQC6 139.1028 −2.89E−01 −1.34E+00 1 Unchanged Low P28838 315.6553 −1.41E+00 −9.33E−02 1 Unchanged Low Q9NZE5 153.3881 1.92E−01 3.36E−01 1 Unchanged Low Q9NX47 263.9291 −9.55E−01 1.75E−01 1 Unchanged Low O60612 179.421 4.43E−01 1.25E+00 1 Unchanged Low O00559 160.9495 −2.31E−01 −3.09E−01 1 Unchanged Low Q9NUU9 172.9723 1.40E−01 6.73E−01 1 Unchanged Low P22059 127.2507 2.16E−01 −5.10E−01 1 Unchanged Low O00408 394.9107 −2.47E+00 −2.34E+00 1 Unchanged Low O94935 142.9113 8.58E−02 −1.94E−01 1 Unchanged Low P41134 293.8674 −1.49E+00 −5.70E−01 1 Unchanged Low P24407 189.5598 −5.30E−01 −2.43E−01 1 Unchanged Low O00232 139.0276 3.42E−01 1.85E−01 1 Unchanged Low Q01432 127.7664 4.83E−01 7.10E−02 1 Unchanged Low Q13525 140.5051 1.92E−01 −6.63E−02 1 Unchanged Low Q16611 210.0516 −8.50E−01 −5.30E−01 1 Unchanged Low Q9NPA3 117.8671 4.67E−01 −3.96E−01 1 Unchanged Low Q9GZM8 141.4354 1.75E−01 −7.41E−02 1 Unchanged Low P42702 120.0363 7.51E−01 2.77E−01 1 Unchanged Low Q05940 227.6447 −1.27E+00 −1.29E+00 1 Unchanged Low Q9Y3Q5 127.0621 1.04E+00 9.77E−01 1 Unchanged Low Q15756 128.583 6.33E−02 −8.81E−01 1 Unchanged Low O75386 122.3782 2.76E−01 −6.39E−01 1 Unchanged Low P50750 213.7777 −7.97E−01 −3.35E−01 1 Unchanged Low Q9NWY6 125.9903 7.65E−01 5.01E−01 1 Unchanged Low P50391 134.9143 1.94E−01 −2.85E−01 1 Unchanged Low Q9NX07 233.9363 −7.26E−01 1.52E−01 1 Unchanged Low O75354 267.133 −1.30E+00 −5.81E−01 1 Unchanged Low Q9H832 212.3427 −1.44E−01 8.22E−01 1 Unchanged Low Q9UBW8 123.4686 6.11E−01 1.05E−01 1 Unchanged Low P14136 117.3353 5.40E−01 −3.21E−01 1 Unchanged Low Q9NYF3 124.4392 3.76E−01 −3.64E−01 1 Unchanged Low Q15056 161.3602 −3.61E−01 −7.09E−01 1 Unchanged Low O15534 179.3665 −5.89E−01 −7.28E−01 1 Unchanged Low Q9Y399 175.5893 −5.44E−01 −7.25E−01 1 Unchanged Low O14972 218.3678 −5.45E−01 2.16E−01 1 Unchanged Low Q14113 126.0667 3.38E−01 −3.92E−01 1 Unchanged Low O95755 129.3518 2.49E−01 −4.55E−01 1 Unchanged Low Q9NPC3 127.8011 6.01E−01 2.17E−01 1 Unchanged Low Q9Y6E9 140.9006 5.00E−01 4.48E−01 1 Unchanged Low Q9Y5B8 122.4719 7.72E−01 3.30E−01 1 Unchanged Low P49642 121.2327 2.27E−01 −9.47E−01 1 Unchanged Low O60660 203.1619 −7.93E−01 −6.34E−01 1 Unchanged Low Q9H251 151.9031 4.86E−01 7.03E−01 1 Unchanged Low Q9Y6C2 119.6097 5.55E−01 −2.28E−01 1 Unchanged Low O95825 145.1487 1.40E−01 −1.17E−01 1 Unchanged Low Q9UHG3 205.2993 −6.57E−01 −2.77E−01 1 Unchanged Low O00629 324.141 −1.71E+00 −8.16E−01 1 Unchanged Low Q15397 134.3527 5.33E−01 2.89E−01 1 Unchanged Low Q14999 134.6153 1.16E+00 1.28E+00 1 Unchanged Low Q12772 137.4667 5.34E−03 −7.46E−01 1 Unchanged Low O75150 152.3442 3.01E−01 3.84E−01 1 Unchanged Low O43423 147.5392 1.84E−01 2.63E−02 1 Unchanged Low O43311 141.3508 −5.12E−02 −7.34E−01 1 Unchanged Low Q9NYX4 171.42 −3.78E−01 −4.91E−01 1 Unchanged Low Q9HD71 141.2517 3.66E−01 1.82E−01 1 Unchanged Low Q9NZH2 187.9443 −4.96E−01 −3.30E−01 1 Unchanged Low Q9NVH1 171.2625 2.16E−01 6.57E−01 1 Unchanged Low Q9NVG3 120.1783 7.30E−01 1.19E−01 1 Unchanged Low P52179 136.9676 2.52E−02 −7.40E−01 1 Unchanged Low O94815 118.2939 7.67E−01 1.04E−01 1 Unchanged Low Q9UBY9 120.3216 6.94E−01 4.08E−02 1 Unchanged Low Q9NVX7 130.905 5.23E−01 1.17E−01 1 Unchanged Low O95704 124.7475 6.90E−01 2.06E−01 1 Unchanged Low P19801 131.0836 −3.80E−02 −1.27E+00 1 Unchanged Low O43709 140.7865 3.28E−01 6.84E−02 1 Unchanged Low Q12839 128.8096 5.50E−01 8.26E−02 1 Unchanged Low O43503 118.1934 7.38E−01 1.83E−02 1 Unchanged Low Q07898 141.7231 8.75E−01 1.01E+00 1 Unchanged Low O96015 168.8465 7.68E−01 1.41E+00 1 Unchanged Low Q92524 259.1219 −1.30E+00 −8.52E−01 1 Unchanged Low Q92692 260.2905 −9.09E−01 6.60E−02 1 Unchanged Low Q9Y6Y8 132.2965 6.30E−01 3.34E−01 1 Unchanged Low Q9NZ78 131.7449 5.90E−01 2.41E−01 1 Unchanged Low Q15120 121.6758 7.42E−01 1.43E−01 1 Unchanged Low P35241 216.9693 −7.74E−01 −3.80E−01 1 Unchanged Low Q9Y326 227.0406 −1.15E+00 −1.17E+00 1 Unchanged Low Q92600 140.923 4.84E−01 3.30E−01 1 Unchanged Low O00487 255.4035 −1.02E+00 −2.60E−01 1 Unchanged Low Q9Y689 152.9706 2.33E−01 2.09E−01 1 Unchanged Low Q9ULB8 124.5785 8.31E−01 4.09E−01 1 Unchanged Low O60897 120.9939 8.59E−01 3.22E−01 1 Unchanged Low P51809 177.2043 −4.94E−01 −6.94E−01 1 Unchanged Low O75581 136.4067 4.05E−01 2.53E−02 1 Unchanged Low O43795 234.504 −6.78E−01 1.20E−01 1 Unchanged Low Q14188 157.7494 5.96E−01 9.25E−01 1 Unchanged Low P06280 214.6169 −1.34E−01 7.70E−01 1 Unchanged Low Q14541 331.895 −1.76E+00 −9.57E−01 1 Unchanged Low P57723 193.1283 −1.97E−01 3.08E−01 1 Unchanged Low Q9NWU3 140.5056 7.22E−02 −5.71E−01 1 Unchanged Low Q9NPC5 122.7442 6.02E−01 −1.24E−01 1 Unchanged Low Q9Y3C5 162.3366 2.40E−02 3.68E−02 1 Unchanged Low Q9NWX3 118.9844 7.23E−01 −4.44E−02 1 Unchanged Low P52742 121.6363 1.00E+00 −5.68E−02 1 Unchanged Low Q9Y313 123.3545 8.56E−01 3.67E−01 1 Unchanged Low Q9P2W9 160.0555 3.45E−01 5.48E−01 1 Unchanged Low P14778 322.4754 −6.95E−01 1.03E+00 1 Unchanged Low Q15464 249.6096 −7.98E−01 8.24E−02 1 Unchanged Low O15444 168.4558 −5.80E−01 −1.33E+00 1 Unchanged Low P49796 161.0774 −4.29E−01 −1.15E+00 1 Unchanged Low Q9NUS7 119.7258 1.00E+00 4.77E−01 1 Unchanged Low P48651 171.5708 −3.72E−01 −6.06E−01 1 Unchanged Low Q07706 150.2019 1.94E−01 7.31E−01 1 Unchanged Low O75143 141.6405 6.20E−01 5.37E−01 1 Unchanged Low O75039 157.7714 −8.78E−02 −3.64E−01 1 Unchanged Low P02261 176.9259 8.10E−01 1.55E+00 1 Unchanged Low Q9H9A0 126.7707 9.27E−01 5.84E−01 1 Unchanged Low Q9NV35 139.1489 7.30E−01 6.33E−01 1 Unchanged Low Q9P1G8 155.3256 4.62E−01 6.08E−01 1 Unchanged Low P26368 163.126 −3.97E−01 −1.01E+00 1 Unchanged Low Q9BSZ7 135.6059 3.34E−01 −2.35E−01 1 Unchanged Low Q9Y391 171.7067 −4.31E−01 −7.99E−01 1 Unchanged Low Q9NYR5 124.8579 7.33E−01 1.46E−01 1 Unchanged Low P05165 128.9755 7.16E−01 2.54E−01 1 Unchanged Low Q9NPF4 127.3658 6.77E−01 1.13E−01 1 Unchanged Low P16106 131.6683 7.44E−01 3.87E−01 1 Unchanged Low P35249 123.3812 6.59E−01 −9.27E−02 1 Unchanged Low P28702 127.7227 1.15E+00 9.23E−01 1 Unchanged Low P49674 136.8564 7.44E−01 5.44E−01 1 Unchanged Low Q9NXW2 216.5041 −5.74E−01 −7.47E−02 1 Unchanged Low O14672 258.8185 −1.18E+00 −7.43E−01 1 Unchanged Low Q9Y5B9 172.4726 3.11E−02 2.04E−01 1 Unchanged Low Q9H9J2 209.7386 −3.07E−01 3.10E−01 1 Unchanged Low P23759 153.0178 8.52E−01 1.11E+00 1 Unchanged Low Q16643 194.7352 −6.66E−01 −8.00E−01 1 Unchanged Low P48454 147.2674 6.57E−01 6.72E−01 1 Unchanged Low Q9Y508 297.9139 −9.88E−01 2.52E−01 1 Unchanged Low P19474 217.1349 −8.47E−01 −7.20E−01 1 Unchanged Low P46109 153.202 1.50E−01 −1.05E−01 1 Unchanged Low P54855 144.2152 2.83E−01 −1.20E−01 1 Unchanged Low Q14242 136.8261 5.72E−01 1.98E−01 1 Unchanged Low Q9BSS1 122.482 9.53E−01 3.78E−01 1 Unchanged Low Q9Y3B2 153.2264 1.44E−01 −1.23E−01 1 Unchanged Low P31391 135.9754 1.89E−01 −6.72E−01 1 Unchanged Low O60623 183.0009 −3.28E−01 −3.12E−01 1 Unchanged Low Q99959 247.4823 −1.11E+00 −7.80E−01 1 Unchanged Low 180.4876 2.72E−01 7.49E−01 1 Unchanged Low Q01658 165.0596 −2.87E−01 −7.54E−01 1 Unchanged Low Q9HCS4 133.5936 1.14E+00 1.03E+00 1 Unchanged Low Q9P035 137.5999 7.12E−01 4.65E−01 1 Unchanged Low Q9C0K7 126.1345 7.19E−01 7.24E−02 1 Unchanged Low Q9NYF4 131.7509 9.09E−01 6.11E−01 1 Unchanged Low P30042 121.6076 7.70E−01 −2.03E−02 1 Unchanged Low O75325 122.705 5.35E−01 −4.82E−01 1 Unchanged Low Q9Y670 118.5764 8.06E−01 −8.69E−02 1 Unchanged Low Q9UPR8 126.797 7.34E−01 1.26E−01 1 Unchanged Low Q9Y2X7 165.5706 7.00E−02 5.72E−02 1 Unchanged Low P47872 184.1802 −4.98E−02 2.60E−01 1 Unchanged Low O43353 276.5684 −6.91E−01 5.11E−01 1 Unchanged Low P32321 149.1554 −3.72E−01 −1.86E+00 1 Unchanged Low O43612 143.2577 1.35E+00 1.55E+00 1 Unchanged Low Q92874 177.8201 −3.69E−01 −5.76E−01 1 Unchanged Low Q9UI90 215.61 9.22E−01 2.12E+00 1 Unchanged Low P30519 380.9032 −1.79E+00 −5.99E−01 1 Unchanged Low Q9NVE7 152.9293 2.57E−01 6.16E−02 1 Unchanged Low Q9P010 214.317 −4.28E−01 1.08E−01 1 Unchanged Low Q9UH59 139.9456 1.99E−01 −5.24E−01 1 Unchanged Low Q9UM82 207.1298 −4.43E−01 −6.20E−02 1 Unchanged Low Q9P2Y4 150.1216 6.84E−01 7.27E−01 1 Unchanged Low Q9GZS3 152.3724 4.47E−01 3.81E−01 1 Unchanged Low P07686 174.0094 −3.52E−01 −6.85E−01 1 Unchanged Low Q9NZV6 204.3052 −5.05E−01 −2.60E−01 1 Unchanged Low O14678 124.9148 1.13E+00 7.10E−01 1 Unchanged Low P29972 204.2885 −8.61E−01 −1.21E+00 1 Unchanged Low O95373 177.0459 −5.38E−01 −1.13E+00 1 Unchanged Low Q15436 120.3545 9.25E−01 1.52E−01 1 Unchanged Low Q9BQ67 141.0924 2.85E−01 −3.25E−01 1 Unchanged Low P35321 156.8515 1.46E+00 1.93E+00 1 Unchanged Low Q9UPQ8 123.4833 1.16E+00 6.76E−01 1 Unchanged Low O43292 119.6038 8.43E−01 −4.59E−02 1 Unchanged Low Q9UBM3 221.0285 −7.49E−01 −4.93E−01 1 Unchanged Low P19338 135.8947 2.02E−01 −7.65E−01 1 Unchanged Low Q9NPE6 139.3341 6.25E−01 2.84E−01 1 Unchanged Low O00442 241.6967 −6.79E−01 2.20E−02 1 Unchanged Low P28356 120.5873 1.02E+00 3.21E−01 1 Unchanged Low P49447 171.1671 −2.56E−02 −6.39E−02 1 Unchanged Low Q9UQA4 289.7702 −4.04E−01 1.05E+00 1 Unchanged Low O15254 185.2853 −1.60E−01 −4.71E−03 1 Unchanged Low Q9NWW6 197.0098 −2.09E−01 1.48E−01 1 Unchanged Low O75391 155.2376 1.59E−01 −1.43E−01 1 Unchanged Low Q92959 120.1434 9.97E−01 2.43E−01 1 Unchanged Low O00499 148.8447 8.25E−02 −5.50E−01 1 Unchanged Low Q14197 121.725 9.24E−01 1.62E−01 1 Unchanged Low Q9NXS9 132.3749 5.07E−01 −2.36E−01 1 Unchanged Low O75954 124.8565 1.05E+00 5.18E−01 1 Unchanged Low Q9UJY9 134.9529 1.41E−01 −1.05E+00 1 Unchanged Low P82912 158.0886 7.17E−01 9.03E−01 1 Unchanged Low Q12918 222.8453 −2.51E−01 4.97E−01 1 Unchanged Low Q14789 154.2154 8.48E−01 1.01E+00 1 Unchanged Low Q04206 248.1566 −9.27E−01 −4.40E−01 1 Unchanged Low P19838 226.323 −4.05E−01 2.71E−01 1 Unchanged Low Q92748 120.9562 7.73E−01 −2.02E−01 1 Unchanged Low O95095 191.35 −2.06E−01 5.88E−03 1 Unchanged Low P52209 177.5327 −2.89E−01 −5.23E−01 1 Unchanged Low P42566 175.3861 −1.68E−01 −3.05E−01 1 Unchanged Low Q13772 271.4641 −6.57E−01 4.26E−01 1 Unchanged Low P43897 241.8156 −9.06E−01 −5.28E−01 1 Unchanged Low P09329 121.5057 7.50E−01 −2.69E−01 1 Unchanged Low O75618 174.3849 2.29E−02 3.61E−02 1 Unchanged Low Q9UHI9 180.2862 4.69E−02 2.18E−01 1 Unchanged Low Q9H824 141.9533 9.76E−01 8.50E−01 1 Unchanged Low Q9UQ43 175.1475 −7.35E−02 −1.64E−01 1 Unchanged Low O43173 217.6266 −3.29E−01 2.12E−01 1 Unchanged Low Q9BZZ2 170.7942 2.55E−01 3.56E−01 1 Unchanged Low Q92611 122.2106 8.70E−01 −3.08E−02 1 Unchanged Low Q969V6 157.6423 3.76E−01 2.49E−01 1 Unchanged Low P08107 145.1219 1.98E−01 −5.38E−01 1 Unchanged Low Q9BQ24 195.2182 1.96E−01 7.29E−01 1 Unchanged Low Q9H7X1 189.2619 1.85E−01 6.03E−01 1 Unchanged Low Q99616 135.6192 4.40E−01 −3.79E−01 1 Unchanged Low Q92896 121.5361 8.54E−01 −1.15E−01 1 Unchanged Low Q14582 210.1876 −2.52E−01 2.12E−01 1 Unchanged Low Q13505 181.2437 −1.73E−01 −2.46E−01 1 Unchanged Low Q13722 135.6336 1.04E+00 7.49E−01 1 Unchanged Low P01308 218.8465 −1.05E+00 −1.70E+00 1 Unchanged Low O00405 238.6383 −3.98E−01 3.92E−01 1 Unchanged Low P41215 214.8046 −5.97E−01 −4.27E−01 1 Unchanged Low P31314 151.5175 7.24E−01 6.60E−01 1 Unchanged Low O95427 125.8189 1.08E+00 4.59E−01 1 Unchanged Low Q12981 119.9152 1.11E+00 2.77E−01 1 Unchanged Low Q9Y5V1 191.3703 −2.55E−01 −2.03E−01 1 Unchanged Low Q9H4B4 177.8629 1.34E−01 2.59E−01 1 Unchanged Low Q9H6D1 126.9312 8.98E−01 1.72E−01 1 Unchanged Low O60504 129.0088 7.02E−01 −1.33E−01 1 Unchanged Low Q9UNK0 189.0342 −2.94E−01 −3.53E−01 1 Unchanged Low O95657 235.2956 −1.06E+00 −1.23E+00 1 Unchanged Low P20645 256.0667 −9.98E−01 −6.03E−01 1 Unchanged Low O14569 126.62 5.40E−01 −6.28E−01 1 Unchanged Low O15293 149.8523 1.82E−01 −4.59E−01 1 Unchanged Low P00390 218.8246 −6.63E−01 −5.24E−01 1 Unchanged Low Q9HBV3 256.1517 −3.62E−01 6.54E−01 1 Unchanged Low Q14558 235.5213 −7.55E−01 −4.09E−01 1 Unchanged Low O14710 209.7103 −5.47E−01 −4.66E−01 1 Unchanged Low Q9UJ70 201.9381 2.41E−01 8.66E−01 1 Unchanged Low Q13397 226.5893 −2.71E−01 4.00E−01 1 Unchanged Low Q9NRG4 200.3335 3.23E−01 9.62E−01 1 Unchanged Low P51449 170.992 −4.03E−01 −1.28E+00 1 Unchanged Low Q9H768 128.0355 1.10E+00 5.33E−01 1 Unchanged Low Q14332 131.3078 1.05E+00 5.76E−01 1 Unchanged Low Q13207 135.2524 5.91E−01 −1.44E−01 1 Unchanged Low Q9H6B8 147.5119 4.18E−01 −6.19E−02 1 Unchanged Low O00462 123.2365 1.11E+00 3.59E−01 1 Unchanged Low Q9Y3D8 173.7578 1.05E−02 −1.31E−01 1 Unchanged Low P17900 178.9056 5.28E−01 8.95E−01 1 Unchanged Low Q9P0M4 221.2511 −5.35E−01 −2.27E−01 1 Unchanged Low 133.5723 1.03E+00 5.94E−01 1 Unchanged Low Q9NZ92 231.4963 −5.71E−01 −1.19E−01 1 Unchanged Low Q9NX94 159.7713 4.32E−01 3.07E−01 1 Unchanged Low P04049 196.2063 −3.19E−01 −2.98E−01 1 Unchanged Low Q13181 158.5133 1.04E−01 −4.02E−01 1 Unchanged Low P22102 218.4202 −7.09E−01 −7.15E−01 1 Unchanged Low Q9NQZ8 138.4428 9.01E−01 5.10E−01 1 Unchanged Low Q9UN30 121.4921 8.93E−01 −1.81E−01 1 Unchanged Low P26651 209.8211 −6.60E−01 −8.17E−01 1 Unchanged Low P18887 122.9254 1.08E+00 2.54E−01 1 Unchanged Low Q9Y2S0 170.8985 −1.36E−02 −3.00E−01 1 Unchanged Low P49023 276.3491 −7.91E−01 9.00E−02 1 Unchanged Low P49321 126.4866 5.97E−01 −6.17E−01 1 Unchanged Low Q13428 156.2838 1.43E−01 −4.18E−01 1 Unchanged Low Q9HCS6 220.0848 3.36E−02 7.66E−01 1 Unchanged Low P20813 155.3947 5.69E−01 4.08E−01 1 Unchanged Low O00459 162.3275 3.20E−01 1.39E−01 1 Unchanged Low P50151 187.0796 −3.47E−02 4.62E−02 1 Unchanged Low Q16850 217.3331 −9.59E−01 −1.61E+00 1 Unchanged Low Q9ULW3 162.0616 9.06E−01 1.09E+00 1 Unchanged Low Q16378 138.8678 1.15E+00 8.95E−01 1 Unchanged Low P41240 170.0806 5.89E−02 −1.98E−01 1 Unchanged Low Q16649 235.1072 −9.55E−01 −1.06E+00 1 Unchanged Low Q9Y3M2 150.2264 1.30E+00 1.38E+00 1 Unchanged Low Q9UK58 229.0134 −6.73E−02 7.10E−01 1 Unchanged Low P47874 201.6274 −4.54E−01 −5.43E−01 1 Unchanged Low O95620 205.8925 −3.16E−01 −1.14E−01 1 Unchanged Low Q9UHV2 163.6559 3.47E−01 1.77E−01 1 Unchanged Low P02810 328.6668 −1.16E+00 −6.62E−02 1 Unchanged Low O94903 190.7733 −3.97E−01 −7.29E−01 1 Unchanged Low Q9P0W6 169.9232 3.04E−01 2.43E−01 1 Unchanged Low Q9H8X4 294.6026 −9.60E−01 −6.84E−02 1 Unchanged Low P02786 254.0696 −8.00E−01 −3.19E−01 1 Unchanged Low 249.0303 −1.07E+00 −1.13E+00 1 Unchanged Low Q99717 188.4757 −3.04E−01 −5.69E−01 1 Unchanged Low Q15036 299.6453 −7.20E−01 4.34E−01 1 Unchanged Low P31751 230.4512 −4.57E−01 −5.57E−03 1 Unchanged Low P11177 188.1769 −3.08E−01 −6.08E−01 1 Unchanged Low Q9UEQ6 167.9086 −4.31E−02 −5.77E−01 1 Unchanged Low Q16531 206.5357 −1.48E−01 1.60E−01 1 Unchanged Low P28698 122.3029 1.28E+00 4.70E−01 1 Unchanged Low P41968 232.6783 −2.81E−01 3.49E−01 1 Unchanged Low P54920 252.9933 −7.24E−01 −2.03E−01 1 Unchanged Low Q99487 218.5222 −2.99E−01 8.00E−02 1 Unchanged Low Q9H0C8 138.517 6.20E−01 −1.49E−01 1 Unchanged Low P17252 122.7553 7.78E−01 −5.50E−01 1 Unchanged Low P06493 123.4207 7.81E−01 −5.05E−01 1 Unchanged Low O00139 177.1988 4.05E−01 5.48E−01 1 Unchanged Low P54259 167.773 1.69E−01 −1.26E−01 1 Unchanged Low Q99757 219.4587 −7.32E−01 −9.21E−01 1 Unchanged Low Q9NW68 178.6551 7.93E−01 1.17E+00 1 Unchanged Low P16106 152.9203 4.33E−01 −3.69E−02 1 Unchanged Low P40692 131.0441 9.15E−01 1.30E−01 1 Unchanged Low Q99798 364.1757 −1.72E+00 −1.08E+00 1 Unchanged Low P53618 175.716 −3.54E−01 −1.23E+00 1 Unchanged Low Q9UJ69 219.0188 −1.80E−01 2.93E−01 1 Unchanged Low Q9NRM2 215.6334 −3.18E−01 −3.70E−02 1 Unchanged Low Q92879 200.6744 −2.16E−01 −1.38E−01 1 Unchanged Low O75399 214.4669 −1.95E−02 4.88E−01 1 Unchanged Low Q9BZE4 184.3092 3.08E−01 5.03E−01 1 Unchanged Low Q9NXB2 243.8822 −4.67E−01 1.38E−01 1 Unchanged Low O95424 158.2861 8.62E−01 8.35E−01 1 Unchanged Low P54577 146.9084 3.66E−01 −4.36E−01 1 Unchanged Low O43692 150.9471 8.73E−01 6.65E−01 1 Unchanged Low O60507 171.4862 −1.67E−02 −4.83E−01 1 Unchanged Low Q9BYS9 134.7877 9.22E−01 2.36E−01 1 Unchanged Low P32780 209.0492 −4.59E−01 −5.25E−01 1 Unchanged Low Q14004 146.1954 1.02E+00 7.68E−01 1 Unchanged Low Q15910 235.9636 −1.75E−01 5.21E−01 1 Unchanged Low P47974 179.8162 8.96E−03 −2.05E−01 1 Unchanged Low Q13177 262.9597 −9.61E−01 −6.63E−01 1 Unchanged Low 188.6409 −4.11E−01 −1.00E+00 1 Unchanged Low P98172 140.4039 6.25E−01 −1.75E−01 1 Unchanged Low Q9BQB1 158.4309 7.36E−01 5.91E−01 1 Unchanged Low O75472 206.8756 −2.58E−01 −1.58E−01 1 Unchanged Low O75608 307.2824 −9.11E−01 6.48E−02 1 Unchanged Low O00193 232.7223 −2.36E−01 3.42E−01 1 Unchanged Low Q14452 164.6255 2.80E−01 −9.75E−02 1 Unchanged Low P55268 155.8763 6.08E−01 2.81E−01 1 Unchanged Low Q9P006 152.156 7.33E−01 3.98E−01 1 Unchanged Low Q9Y365 175.2567 2.65E−01 1.52E−01 1 Unchanged Low Q9NQ34 165.3815 4.02E−01 1.59E−01 1 Unchanged Low Q9NWY4 123.5579 1.45E+00 6.46E−01 1 Unchanged Low Q9UBS8 221.9109 −2.54E−01 1.13E−01 1 Unchanged Low Q9UBS4 182.7428 7.25E−02 −5.40E−02 1 Unchanged Low Q12797 126.3618 9.19E−01 −2.27E−01 1 Unchanged Low Q9H4I9 192.7801 1.93E−01 3.89E−01 1 Unchanged Low O14907 315.6313 −8.75E−01 1.97E−01 1 Unchanged Low Q14673 135.533 9.82E−01 2.74E−01 1 Unchanged Low Q9NWB7 281.455 −1.56E+00 −2.75E+00 1 Unchanged Low Q9BVH4 175.4765 2.23E−01 3.72E−02 1 Unchanged Low P22897 123.4215 1.32E+00 3.78E−01 1 Unchanged Low P19012 156.5003 3.94E−01 −1.69E−01 1 Unchanged Low Q14738 200.124 −2.19E−01 −2.94E−01 1 Unchanged Low O95152 195.3686 −3.47E−02 −1.53E−02 1 Unchanged Low P78426 248.2544 −4.06E−02 8.31E−01 1 Unchanged Low Q14790 200.6718 6.29E−01 1.19E+00 1 Unchanged Low P07711 150.5861 4.94E−01 −1.75E−01 1 Unchanged Low P32942 157.6897 4.61E−01 −8.57E−03 1 Unchanged Low 171.3764 4.00E−02 −5.29E−01 1 Unchanged Low Q9NWS0 127.6547 1.26E+00 3.99E−01 1 Unchanged Low Q9NWZ5 242.9739 1.42E−01 1.02E+00 1 Unchanged Low O75792 131.5441 9.56E−01 −1.12E−02 1 Unchanged Low P05141 320.3918 −1.22E+00 −5.47E−01 1 Unchanged Low Q9NX38 165.7012 4.72E−01 1.95E−01 1 Unchanged Low Q9Y682 220.1941 1.21E−02 4.86E−01 1 Unchanged Low P78381 226.4009 −4.97E−01 −4.14E−01 1 Unchanged Low Q9UMP5 214.9641 −4.67E−01 −5.97E−01 1 Unchanged Low Q9P0Q0 188.838 5.95E−01 8.96E−01 1 Unchanged Low Q9UBQ3 185.7473 4.72E−02 −1.39E−01 1 Unchanged Low P27540 231.071 −2.91E−01 1.07E−01 1 Unchanged Low Q9Y2W1 201.3236 2.89E−01 6.30E−01 1 Unchanged Low P82267 208.571 −2.07E−02 2.20E−01 1 Unchanged Low P00918 216.9569 −5.33E−01 −7.25E−01 1 Unchanged Low Q9Y663 184.9847 −4.02E−01 −1.38E+00 1 Unchanged Low Q9NX40 187.7106 7.14E−01 1.05E+00 1 Unchanged Low P50222 195.0839 2.50E−01 4.34E−01 1 Unchanged Low Q13610 229.4375 2.90E−01 1.04E+00 1 Unchanged Low P49591 139.6467 3.68E−01 −1.13E+00 1 Unchanged Low P04554 269.3189 −6.77E−01 −8.89E−02 1 Unchanged Low P02538 233.9139 −2.09E−01 2.80E−01 1 Unchanged Low Q13637 286.1382 −9.91E−01 −5.43E−01 1 Unchanged Low P39086 197.2285 9.83E−02 1.88E−01 1 Unchanged Low Q9H8F9 228.8927 −5.40E−01 −5.06E−01 1 Unchanged Low Q99460 241.22 −5.96E−01 −3.89E−01 1 Unchanged Low Q9UKP6 184.3366 −1.11E−01 −5.86E−01 1 Unchanged Low Q16589 170.3526 9.88E−01 1.10E+00 1 Unchanged Low O95316 162.324 4.48E−01 −2.40E−03 1 Unchanged Low O14545 241.5146 −2.69E−01 2.74E−01 1 Unchanged Low Q9Y249 204.4863 5.18E−02 2.31E−01 1 Unchanged Low Q92794 170.3523 5.64E−01 4.13E−01 1 Unchanged Low P36894 194.5315 4.11E−01 6.59E−01 1 Unchanged Low P79525 148.0291 7.17E−01 4.53E−02 1 Unchanged Low O14947 281.2972 −8.57E−01 −3.47E−01 1 Unchanged Low Q12899 212.5994 7.89E−02 4.05E−01 1 Unchanged Low 142.4645 1.13E+00 5.79E−01 1 Unchanged Low Q9UIJ5 362.7132 −1.13E+00 5.01E−02 1 Unchanged Low P46821 152.4972 7.21E−01 1.70E−01 1 Unchanged Low O60906 254.5351 −5.00E−01 −7.08E−03 1 Unchanged Low P04040 199.8034 3.15E−01 5.71E−01 1 Unchanged Low O60709 168.4792 1.23E+00 1.37E+00 1 Unchanged Low Q14714 242.1486 −9.20E−01 −1.36E+00 1 Unchanged Low P39687 178.3873 −1.80E−01 −1.07E+00 1 Unchanged Low O75341 187.1088 3.99E−01 4.62E−01 1 Unchanged Low Q9NUN1 182.989 3.94E−01 3.60E−01 1 Unchanged Low Q9UHR5 256.9591 −1.65E−01 6.16E−01 1 Unchanged Low Q9UMX3 187.4707 1.18E−01 −7.26E−02 1 Unchanged Low Q02297 175.0464 1.17E+00 1.39E+00 1 Unchanged Low Q9BQ83 300.7124 −5.89E−01 3.95E−01 1 Unchanged Low O43491 203.6633 −3.98E−01 −8.84E−01 1 Unchanged Low Q92922 216.0309 −3.18E−01 −3.64E−01 1 Unchanged Low Q16099 229.9201 1.17E−02 5.26E−01 1 Unchanged Low O95328 231.7737 −3.29E−01 −7.56E−02 1 Unchanged Low Q06265 183.9827 2.73E−01 1.25E−01 1 Unchanged Low Q01780 223.1866 3.82E−02 4.57E−01 1 Unchanged Low Q9NPF9 207.9337 −3.14E−01 −5.70E−01 1 Unchanged Low Q9P1U0 154.8483 8.72E−01 4.48E−01 1 Unchanged Low Q13480 174.7367 2.43E−01 −1.98E−01 1 Unchanged Low O95205 202.2261 5.72E−01 9.62E−01 1 Unchanged Low O76091 192.2638 6.67E−02 −1.17E−01 1 Unchanged Low Q9Y364 244.4561 −3.22E−02 6.28E−01 1 Unchanged Low P51116 210.8166 −8.49E−02 −2.12E−02 1 Unchanged Low P49915 164.6237 2.15E−01 −6.13E−01 1 Unchanged Low Q9UHR3 173.3257 7.64E−01 7.09E−01 1 Unchanged Low Q15007 233.0967 −2.15E−01 1.22E−01 1 Unchanged Low P24941 172.2468 1.05E+00 1.12E+00 1 Unchanged Low P53634 126.6548 1.07E+00 −3.22E−01 1 Unchanged Low Q13123 155.5636 9.16E−01 4.95E−01 1 Unchanged Low Q9NUT6 351.7208 −4.77E−01 9.85E−01 1 Unchanged Low Q9Y279 262.6019 −7.99E−01 −6.59E−01 1 Unchanged Low O75319 220.2678 −2.87E−01 −2.84E−01 1 Unchanged Low Q9NYH9 258.6032 −4.85E−01 −1.99E−02 1 Unchanged Low Q9UNF0 331.0599 −1.09E+00 −3.29E−01 1 Unchanged Low O60437 316.8358 −1.11E+00 −5.61E−01 1 Unchanged Low Q9NZN8 206.5153 1.17E−01 2.41E−01 1 Unchanged Low Q14232 229.9659 −4.12E−01 −3.79E−01 1 Unchanged Low O00142 159.1674 7.24E−01 2.35E−01 1 Unchanged Low O60443 197.4327 7.53E−01 1.11E+00 1 Unchanged Low O95406 175.4375 1.84E−01 −3.95E−01 1 Unchanged Low Q12841 128.3877 1.35E+00 2.72E−01 1 Unchanged Low O15217 125.424 1.40E+00 2.20E−01 1 Unchanged Low P10645 201.8922 8.38E−01 1.29E+00 1 Unchanged Low Q9HA66 199.1923 6.24E−02 −4.27E−02 1 Unchanged Low Q9Y439 230.9065 2.37E−01 8.19E−01 1 Unchanged Low Q9Y386 259.7061 −6.48E−01 −4.06E−01 1 Unchanged Low P53990 279.676 −1.46E−01 8.01E−01 1 Unchanged Low O95865 163.3476 7.35E−01 3.29E−01 1 Unchanged Low 193.5142 5.44E−01 6.86E−01 1 Unchanged Low Q15834 251.6031 −6.24E−01 −5.06E−01 1 Unchanged Low P18846 295.2222 −1.18E+00 −1.19E+00 1 Unchanged Low Q14349 174.3142 5.87E−01 3.37E−01 1 Unchanged Low Q9NVM5 140.794 1.09E+00 2.30E−01 1 Unchanged Low P12955 178.2362 6.43E−01 5.20E−01 1 Unchanged Low Q99700 213.1956 1.30E−01 3.27E−01 1 Unchanged Low Q9UJA2 219.8275 6.40E−01 1.23E+00 1 Unchanged Low Q02246 128.7469 9.55E−01 −6.50E−01 1 Unchanged Low P48553 198.4177 5.00E−01 6.84E−01 1 Unchanged Low Q99639 243.5051 −1.02E−01 3.92E−01 1 Unchanged Low Q9NQX5 201.225 1.58E−01 1.30E−01 1 Unchanged Low Q99799 196.7655 3.13E−02 −2.32E−01 1 Unchanged Low Q9BZV1 191.2074 7.17E−01 8.86E−01 1 Unchanged Low Q03113 154.1344 5.82E−01 −3.22E−01 1 Unchanged Low P01130 301.7776 −5.17E−01 3.87E−01 1 Unchanged Low Q9UHN6 174.2344 2.08E−01 −4.89E−01 1 Unchanged Low Q99738 205.0214 7.00E−02 2.10E−02 1 Unchanged Low Q9Y576 136.0527 8.00E−01 −6.69E−01 1 Unchanged Low P02304 161.1406 1.38E+00 1.24E+00 1 Unchanged Low P01118 219.9522 1.10E−02 1.93E−01 1 Unchanged Low P15924 241.3819 −2.44E−01 7.48E−02 1 Unchanged Low O43597 161.8627 8.21E−01 3.75E−01 1 Unchanged Low P09622 263.2128 −7.14E−01 −5.77E−01 1 Unchanged Low Q08257 342.4839 −1.28E+00 −7.73E−01 1 Unchanged Low Q9UHY8 131.2705 1.29E+00 1.31E−01 1 Unchanged Low P10646 422.403 −1.49E+00 −3.81E−01 1 Unchanged Low Q92685 208.1394 1.21E−01 1.53E−01 1 Unchanged Low P34949 149.8251 1.05E+00 4.00E−01 1 Unchanged Low Q9NPE9 153.7649 1.21E+00 7.81E−01 1 Unchanged Low Q99853 153.0918 5.87E−01 −4.25E−01 1 Unchanged Low Q9HD41 241.047 −3.97E−01 −2.85E−01 1 Unchanged Low Q16625 470.2634 −2.01E+00 −1.35E+00 1 Unchanged Low P45973 167.3186 3.70E−01 −4.13E−01 1 Unchanged Low Q9NVI9 161.8885 6.47E−01 3.42E−03 1 Unchanged Low P37173 178.0564 9.24E−01 8.90E−01 1 Unchanged Low Q9UKF7 277.9863 −6.44E−01 −2.18E−01 1 Unchanged Low P16870 144.0377 1.38E+00 7.40E−01 1 Unchanged Low P00374 140.6638 5.22E−01 −1.32E+00 1 Unchanged Low P19957 333.0661 7.60E−02 1.52E+00 1 Unchanged Low O75962 215.0154 −1.28E−01 −2.45E−01 1 Unchanged Low P16050 196.6194 −4.31E−01 −1.72E+00 1 Unchanged Low Q9Y3D2 213.0068 9.09E−02 1.57E−01 1 Unchanged Low O00505 295.4165 −7.45E−01 −1.96E−01 1 Unchanged Low Q9NZD8 220.0079 −5.62E−02 6.21E−04 1 Unchanged Low P46937 233.924 −3.10E−02 2.93E−01 1 Unchanged Low P53384 236.5867 −3.45E−01 −2.91E−01 1 Unchanged Low Q9UI28 160.6424 8.34E−01 2.84E−01 1 Unchanged Low Q14651 345.2493 −1.27E+00 −7.72E−01 1 Unchanged Low P10914 306.8604 −5.32E−01 3.46E−01 1 Unchanged Low P21281 383.914 −4.76E−01 1.09E+00 1 Unchanged Low P53701 293.8906 −2.28E−01 7.19E−01 1 Unchanged Low Q9Y2B1 147.2535 1.06E+00 2.50E−01 1 Unchanged Low Q14166 274.7657 −6.26E−01 −2.68E−01 1 Unchanged Low Q15738 213.0647 −2.31E−01 −5.69E−01 1 Unchanged Low Q16586 234.3861 −7.31E−01 −1.47E+00 1 Unchanged Low Q9Y6J8 272.4953 −3.48E−01 2.48E−01 1 Unchanged Low Q9H5F2 250.8425 8.24E−02 7.03E−01 1 Unchanged Low Q05655 310.8344 −9.58E−01 −5.00E−01 1 Unchanged Low Q9NXU7 230.6008 −1.54E−01 −3.21E−02 1 Unchanged Low O15498 215.7355 1.98E−01 3.54E−01 1 Unchanged Low Q92664 242.5829 −5.54E−01 −7.23E−01 1 Unchanged Low Q9Y223 239.9617 6.67E−02 5.11E−01 1 Unchanged Low O95816 132.1461 1.36E+00 1.53E−01 1 Unchanged Low Q9H0K5 244.8706 1.72E−01 7.45E−01 1 Unchanged Low Q9BTJ1 253.7125 7.24E−01 1.64E+00 1 Unchanged Low Q9NRR5 185.8791 6.60E−01 5.40E−01 1 Unchanged Low Q9Y5L3 256.4569 −1.07E−01 4.24E−01 1 Unchanged Low O75351 267.9692 −3.29E−01 1.78E−01 1 Unchanged Low O75443 184.2202 2.54E−01 −2.86E−01 1 Unchanged Low Q9H7X4 286.2489 −2.94E−01 4.71E−01 1 Unchanged Low O00255 156.9374 7.01E−01 −2.02E−01 1 Unchanged Low Q9BV94 284.912 −5.42E−01 −1.37E−02 1 Unchanged Low O14813 255.131 −4.57E−02 4.99E−01 1 Unchanged Low P35269 225.4377 −1.49E−01 −1.98E−01 1 Unchanged Low Q12891 287.6363 −5.88E−01 −9.12E−02 1 Unchanged Low O15162 419.5068 −9.98E−01 4.39E−01 1 Unchanged Low Q14469 207.739 5.48E−01 7.31E−01 1 Unchanged Low P06241 136.7385 1.06E+00 −3.67E−01 1 Unchanged Low Q9BVG9 215.8454 −2.60E−02 −1.71E−01 1 Unchanged Low Q9P0P9 315.5648 −3.84E−01 5.78E−01 1 Unchanged Low Q9UMF9 224.2505 1.01E−01 2.24E−01 1 Unchanged Low Q03527 316.1666 −9.88E−01 −6.36E−01 1 Unchanged Low P31153 200.5541 −1.38E−01 −8.75E−01 1 Unchanged Low Q04741 217.4148 −1.10E−01 −3.46E−01 1 Unchanged Low Q13153 247.6258 −1.26E−01 1.87E−01 1 Unchanged Low Q9Y388 168.2598 1.15E+00 8.44E−01 1 Unchanged Low Q9HC14 193.9429 4.92E−01 3.31E−01 1 Unchanged Low P30281 166.0499 1.05E+00 6.39E−01 1 Unchanged Low Q9UFK2 188.8934 7.48E−01 6.60E−01 1 Unchanged Low Q13011 278.2904 −5.95E−01 −3.07E−01 1 Unchanged Low P09601 278.3661 2.63E−01 1.19E+00 1 Unchanged Low Q9BVZ8 159.346 8.23E−01 6.71E−03 1 Unchanged Low Q13889 179.5227 9.99E−01 8.50E−01 1 Unchanged Low P49703 147.0234 8.35E−01 −4.62E−01 1 Unchanged Low Q9GZU7 226.5474 −4.46E−01 −1.03E+00 1 Unchanged Low P10253 189.0733 2.59E−01 −2.69E−01 1 Unchanged Low Q9Y3V5 318.1897 −4.37E−01 4.89E−01 1 Unchanged Low O14773 202.7117 4.04E−01 3.35E−01 1 Unchanged Low P22061 168.6387 9.26E−01 4.66E−01 1 Unchanged Low P14868 140.1468 9.42E−01 −5.85E−01 1 Unchanged Low Q14938 134.9545 1.25E+00 −1.55E−01 1 Unchanged Low O75968 219.072 6.29E−02 −1.06E−03 1 Unchanged Low Q9H779 225.7323 7.06E−01 1.18E+00 1 Unchanged Low Q9BX72 188.9468 4.18E−01 2.61E−02 1 Unchanged Low O43563 169.4168 7.56E−01 1.53E−01 1 Unchanged Low O15142 230.3093 −1.47E−01 −2.22E−01 1 Unchanged Low Q9UJ41 171.2118 8.94E−01 4.38E−01 1 Unchanged Low P05231 379.972 −8.48E−02 1.49E+00 1 Unchanged Low Q9Y2H0 271.9604 −3.04E−01 1.48E−01 1 Unchanged Low Q9UJT9 269.5315 −3.44E−01 2.98E−02 1 Unchanged Low Q9Y306 187.7391 6.28E−01 3.69E−01 1 Unchanged Low Q9Y6A6 190.8287 3.79E−01 −2.97E−02 1 Unchanged Low O75300 133.1515 1.20E+00 −4.21E−01 1 Unchanged Low P51798 263.0106 −2.86E−01 1.98E−02 1 Unchanged Low Q14839 164.8091 1.12E+00 6.20E−01 1 Unchanged Low O60299 232.6614 7.85E−01 1.35E+00 1 Unchanged Low Q9Y6F1 292.1577 −1.24E−01 6.80E−01 1 Unchanged Low O15212 256.7661 −1.30E−01 2.22E−01 1 Unchanged Low Q9Y2W2 289.1386 −5.51E−01 −1.42E−01 1 Unchanged Low Q9UKN5 187.2825 −1.44E−01 −1.65E+00 1 Unchanged Low Q00978 312.2774 −4.09E−01 4.13E−01 1 Unchanged Low Q9UHY0 263.8122 −3.71E−01 −1.50E−01 1 Unchanged Low Q9Y248 130.5748 1.31E+00 −3.95E−01 1 Unchanged Low O96019 267.9206 3.79E−03 5.92E−01 1 Unchanged Low P10276 200.7048 −1.22E−01 −1.03E+00 1 Unchanged Low Q9BUC7 254.8265 7.52E−01 1.55E+00 1 Unchanged Low Q9HAC1 156.9785 6.81E−01 −5.57E−01 1 Unchanged Low Q93078 204.3058 3.56E−01 1.72E−01 1 Unchanged Low P08572 129.2665 1.72E+00 3.15E−01 1 Unchanged Low P15056 199.7155 2.51E−01 −1.59E−01 1 Unchanged Low Q15543 238.5733 5.70E−02 2.38E−01 1 Unchanged Low O14901 262.1749 −2.63E−01 −4.43E−03 1 Unchanged Low 267.6704 −4.37E−01 −2.87E−01 1 Unchanged Low P51965 386.4499 −1.32E−01 1.40E+00 1 Unchanged Low Q9Y3R2 263.1006 −5.43E−01 −6.31E−01 1 Unchanged Low O94829 213.3188 5.30E−01 6.17E−01 1 Unchanged Low Q92859 211.5326 6.04E−01 7.01E−01 1 Unchanged Low Q12846 216.5887 −4.74E−01 −1.80E+00 1 Unchanged Low P01286 244.6261 −2.83E−02 1.47E−01 1 Unchanged Low Q9UH92 200.1328 4.33E−01 1.72E−01 1 Unchanged Low O75323 193.2783 3.89E−01 −8.78E−02 1 Unchanged Low Q9UQ33 156.5563 1.20E+00 3.93E−01 1 Unchanged Low Q9Y3A7 282.2981 −7.79E−01 −9.34E−01 1 Unchanged Low Q9Y2Z0 224.9662 3.44E−01 4.71E−01 1 Unchanged Low P56211 299.2676 −2.41E−01 4.81E−01 1 Unchanged Low P21127 232.4012 5.59E−01 9.32E−01 1 Unchanged Low Q07866 299.1796 −1.19E−01 6.82E−01 1 Unchanged Low Q9BTI3 231.0835 3.62E−02 8.33E−03 1 Unchanged Low Q9H2J4 243.2412 −2.27E−02 1.00E−01 1 Unchanged Low Q9NXE5 275.9024 2.79E−01 1.04E+00 1 Unchanged Low Q92572 176.703 1.45E+00 1.27E+00 1 Unchanged Low Q9NXT6 255.685 −1.14E−01 1.20E−01 1 Unchanged Low O15321 252.5647 −3.24E−01 −3.79E−01 1 Unchanged Low O15383 360.7235 −7.73E−01 1.39E−01 1 Unchanged Low O60403 245.2774 −1.12E−02 1.41E−01 1 Unchanged Low P49354 201.1077 4.40E−01 1.54E−01 1 Unchanged Low P48039 249.7986 −3.69E−01 −5.51E−01 1 Unchanged Low O43562 158.9844 1.03E+00 1.20E−01 1 Unchanged Low Q9HC89 230.2337 1.56E−01 1.93E−01 1 Unchanged Low P00790 253.0491 −1.13E−01 5.77E−02 1 Unchanged Low Q9NVP1 134.724 1.59E+00 1.83E−01 1 Unchanged Low Q9UBN1 289.0967 −1.88E−01 4.16E−01 1 Unchanged Low P35659 131.6712 1.57E+00 −4.06E−02 1 Unchanged Low P54252 222.5126 5.98E−01 8.03E−01 1 Unchanged Low Q14152 289.959 −6.19E−01 −4.43E−01 1 Unchanged Low Q9Y314 193.3594 9.44E−01 8.31E−01 1 Unchanged Low Q9NRC7 233.7238 8.04E−01 1.27E+00 1 Unchanged Low P02533 210.4458 2.25E−01 −9.66E−02 1 Unchanged Low O60907 194.8701 4.34E−01 −4.19E−02 1 Unchanged Low P43155 238.6829 −2.78E−01 −6.03E−01 1 Unchanged Low Q15077 292.1056 −7.12E−01 −6.52E−01 1 Unchanged Low Q12840 252.8959 −7.25E−04 2.43E−01 1 Unchanged Low P26599 247.8557 5.71E−01 1.10E+00 1 Unchanged Low Q9Y316 338.8101 −9.17E−01 −4.62E−01 1 Unchanged Low P24394 292.7071 −3.75E−01 9.24E−02 1 Unchanged Low P32418 181.3894 4.77E−01 −3.56E−01 1 Unchanged Low P42694 183.6122 5.27E−01 −1.79E−01 1 Unchanged Low O60755 223.2368 5.54E−01 7.22E−01 1 Unchanged Low Q16204 218.6477 3.14E−01 2.29E−01 1 Unchanged Low Q12980 198.8702 3.79E−01 −7.95E−02 1 Unchanged Low P08559 273.612 −6.48E−01 −8.63E−01 1 Unchanged Low Q9Y2U9 173.6438 9.10E−01 2.70E−01 1 Unchanged Low Q9Y2T2 323.8714 −4.92E−01 2.29E−01 1 Unchanged Low Q13105 220.1539 4.32E−01 4.47E−01 1 Unchanged Low Q9H1J1 192.8261 6.45E−01 2.50E−01 1 Unchanged Low Q08752 296.8872 −8.89E−01 −1.13E+00 1 Unchanged Low P38159 253.2584 −5.07E−01 −9.58E−01 1 Unchanged Low Q9Y337 256.4089 1.62E−01 5.36E−01 1 Unchanged Low P25445 186.0304 1.24E+00 1.07E+00 1 Unchanged Low Q9BZH1 268.2725 −5.39E−01 −7.24E−01 1 Unchanged Low O43633 260.7188 −3.53E−01 −4.10E−01 1 Unchanged Low Q99536 288.1564 1.17E−01 8.44E−01 1 Unchanged Low P24557 268.1689 −4.34E−01 −4.66E−01 1 Unchanged Low O75369 344.1714 −4.56E−01 4.69E−01 1 Unchanged Low P50453 350.7941 −8.60E−01 −2.49E−01 1 Unchanged Low P35680 217.2497 4.28E−02 −4.40E−01 1 Unchanged Low Q03924 267.2646 −8.70E−02 2.24E−01 1 Unchanged Low Q9NRQ5 309.8867 −5.76E−01 −1.56E−01 1 Unchanged Low Q99867 289.1694 −6.29E−01 −6.08E−01 1 Unchanged Low Q9H682 271.5091 2.46E−01 8.28E−01 1 Unchanged Low O00148 214.3036 −8.71E−02 −8.92E−01 1 Unchanged Low 236.7141 5.15E−01 7.91E−01 1 Unchanged Low Q9UG51 283.0875 −1.69E−01 2.70E−01 1 Unchanged Low O75175 242.329 8.45E−02 1.35E−01 1 Unchanged Low Q9GZQ8 300.1702 −1.00E−01 5.94E−01 1 Unchanged Low P19438 224.9565 6.66E−02 −2.43E−01 1 Unchanged Low Q9NRR8 303.9389 −4.68E−01 −3.97E−02 1 Unchanged Low O95162 169.1352 6.60E−01 −5.27E−01 1 Unchanged Low O95279 215.5542 −1.63E−01 −1.11E+00 1 Unchanged Low Q9NTW4 289.1446 −7.18E−01 −8.83E−01 1 Unchanged Low Q9NWM9 191.4607 1.02E+00 7.69E−01 1 Unchanged Low P40121 370.7982 −8.79E−01 −1.26E−01 1 Unchanged Low Q92466 188.2839 1.31E+00 1.15E+00 1 Unchanged Low O43365 191.5647 8.91E−01 5.60E−01 1 Unchanged Low Q9NVJ7 288.7892 −4.48E−01 −2.44E−01 1 Unchanged Low Q9NVY5 202.4155 4.36E−01 −3.55E−02 1 Unchanged Low Q9BY40 173.0132 8.07E−01 −1.06E−01 1 Unchanged Low Q9NZE2 152.875 1.69E+00 8.23E−01 1 Unchanged Low P29275 264.0659 −5.21E−01 −8.95E−01 1 Unchanged Low Q9NZE0 133.8159 1.58E+00 −2.18E−01 1 Unchanged Low Q03111 211.7891 1.39E−01 −4.71E−01 1 Unchanged Low Q08499 155.5405 9.83E−01 −4.34E−01 1 Unchanged Low Q15628 237.3623 2.13E−01 2.21E−01 1 Unchanged Low Q9Y657 222.9201 1.89E−01 −1.07E−01 1 Unchanged Low Q9UHQ1 288.0624 −3.32E−01 −4.84E−02 1 Unchanged Low P17980 257.496 −4.13E−01 −7.81E−01 1 Unchanged Low P45877 194.3167 5.93E−01 3.30E−02 1 Unchanged Low O95340 149.5355 1.17E+00 −3.26E−01 1 Unchanged Low Q9H9Z7 228.8009 6.52E−01 8.13E−01 1 Unchanged Low O15172 287.4495 −3.68E−01 −1.45−01 1 Unchanged Low P01298 329.1527 −1.13+00 −1.49E+00 1 Unchanged Low Q13395 248.0711 −6.41E−02 −1.55E−01 1 Unchanged Low O15551 259.744 −1.66E−01 −1.64E−01 1 Unchanged Low P55060 282.6907 −3.68E−01 −2.21E−01 1 Unchanged Low O43286 344.9578 −3.42E−01 5.65E−01 1 Unchanged Low P04424 371.2796 −1.25E+00 −1.15E+00 1 Unchanged Low Q9NWR5 224.6496 5.41E−01 5.50E−01 1 Unchanged Low Q9BUN8 197.0059 5.95E−01 7.92E−02 1 Unchanged Low P49760 138.8925 1.85E+00 4.88E−01 1 Unchanged Low Q9UEG3 284.5589 −5.53E−01 −6.42E−01 1 Unchanged Low Q9P0Y6 258.2636 −9.74E−02 −6.63E−02 1 Unchanged Low Q92535 213.6071 2.01E−01 −3.46E−01 1 Unchanged Low Q00577 454.6488 −1.74E+00 −1.62E+00 1 Unchanged Low O75717 242.2724 1.52E−01 1.44E−01 1 Unchanged Low P04278 221.0173 2.20E−01 −1.36E−01 1 Unchanged Low P51124 158.1827 1.21E+00 7.09E−02 1 Unchanged Low P15259 315.8301 −4.05E−01 1.22E−01 1 Unchanged Low Q12893 235.3565 5.32E−01 6.82E−01 1 Unchanged Low P57738 217.0429 5.99E−01 4.80E−01 1 Unchanged Low P24863 481.4089 −1.41E+00 −3.55E−01 1 Unchanged Low Q9Y370 187.603 7.17E−01 2.82E−02 1 Unchanged Low Q9HD89 208.2163 4.13E−01 −6.07E−02 1 Unchanged Low O14807 179.5238 1.27E+00 7.81E−01 1 Unchanged Low Q13435 263.6077 −9.65E−02 −1.45E−02 1 Unchanged Low Q9UMY4 219.6698 5.00E−01 3.45E−01 1 Unchanged Low O43929 291.5955 −7.92E−02 4.04E−01 1 Unchanged Low Q9BZQ1 278.4192 2.07E−01 7.21E−01 1 Unchanged Low P55042 355.8906 −2.46E−01 7.73E−01 1 Unchanged Low Q92870 135.8422 1.74E+00 3.40E−02 1 Unchanged Low P33778 271.5522 5.84E−01 1.21E+00 1 Unchanged Low Q9ULZ3 342.2046 −1.06E−02 1.01E+00 1 Unchanged Low Q13485 199.4935 6.40E−01 1.51E−01 1 Unchanged Low Q9H684 280.5396 −3.61E−01 −3.26E−01 1 Unchanged Low Q9H7F8 234.2579 4.22E−01 4.40E−01 1 Unchanged Low Q92508 237.2652 8.06E−02 −1.62E−01 1 Unchanged Low Q9UM47 150.552 1.97E+00 1.02E+00 1 Unchanged Low P18084 214.6124 −2.33E−02 −1.00E+00 1 Unchanged Low Q99462 213.9424 2.98E−01 −2.15E−01 1 Unchanged Low O75619 262.7733 3.68E−01 7.56E−01 1 Unchanged Low Q92733 238.8334 3.55E−01 3.76E−01 1 Unchanged Low Q15796 359.5423 −5.57E−01 2.42E−01 1 Unchanged Low P15291 357.1444 −6.81E−01 −3.31E−02 1 Unchanged Low Q99417 259.037 −4.00E−02 −4.48E−02 1 Unchanged Low P06732 195.4365 3.45E−01 −6.78E−01 1 Unchanged Low P50570 244.4335 5.20E−02 −1.23E−01 1 Unchanged Low Q9Y5A9 329.2557 −4.82E−01 4.59E−02 1 Unchanged Low Q92841 252.4572 1.66E−01 2.30E−01 1 Unchanged Low P51808 228.2619 5.01E−01 4.24E−01 1 Unchanged Low O95758 377.5392 −6.74E−01 1.67E−01 1 Unchanged Low P32970 386.0177 −7.79E−01 4.11E−02 1 Unchanged Low O75689 259.1653 4.32E−01 7.71E−01 1 Unchanged Low P55072 362.8018 −8.50E−01 −3.63E−01 1 Unchanged Low P47813 360.7943 −9.10E−01 −5.31E−01 1 Unchanged Low Q15532 220.5805 4.41E−01 1.50E−01 1 Unchanged Low Q15813 192.1296 7.78E−01 1.33E−01 1 Unchanged Low P14373 270.5765 −1.24E−01 −6.68E−02 1 Unchanged Low O14980 235.5264 1.17E−01 −2.08E−01 1 Unchanged Low P07942 141.0764 1.87E+00 3.80E−01 1 Unchanged Low P53041 242.7533 −6.88E−02 −4.76E−01 1 Unchanged Low Q07820 288.4688 −4.79E−01 −5.78E−01 1 Unchanged Low P53816 474.8201 −1.22E+00 −1.19E−01 1 Unchanged Low Q9P1C8 234.8631 1.23E−01 −2.19E−01 1 Unchanged Low P51966 217.1092 8.11E−01 7.10E−01 1 Unchanged Low Q99739 237.5556 5.44E−01 6.14E−01 1 Unchanged Low P35913 210.8879 3.86E−01 −2.07E−01 1 Unchanged Low P52756 257.2441 −1.04E−01 −2.87E−01 1 Unchanged Low Q9NXX5 196.0576 1.01E+00 5.96E−01 1 Unchanged Low Q14498 224.4664 4.16E−01 1.38E−01 1 Unchanged Low P28069 243.064 3.28E−03 −3.41E−01 1 Unchanged Low P51397 307.4499 −4.10E−01 −1.57E−01 1 Unchanged Low Q9NUI8 249.4637 7.36E−01 1.06E+00 1 Unchanged Low O00322 260.1175 2.30E−01 3.99E−01 1 Unchanged Low P78368 248.257 3.12E−01 3.63E−01 1 Unchanged Low Q01081 163.878 9.24E−01 −5.98E−01 1 Unchanged Low O43193 179.1305 1.91E+00 1.56E+00 1 Unchanged Low Q9Y3B0 204.6742 5.89E−01 2.03E−02 1 Unchanged Low Q9NV80 239.9609 5.57E−01 6.43E−01 1 Unchanged Low Q9Y473 226.3406 8.96E−01 9.57E−01 1 Unchanged Low Q9Y548 245.7773 1.74E−01 4.14E−02 1 Unchanged Low Q13952 286.4173 1.25E−01 5.50E−01 1 Unchanged Low P18615 247.7362 1.54E−01 3.25E−02 1 Unchanged Low P33241 163.4955 1.48E+00 4.71E−01 1 Unchanged Low O15116 362.8572 −3.81E−01 4.74E−01 1 Unchanged Low P50897 177.9416 1.06E+00 1.69E−01 1 Unchanged Low 209.3298 9.77E−01 7.63E−01 1 Unchanged Low Q9Y3A5 426.2946 −8.25E−01 2.14E−01 1 Unchanged Low Q9BVT1 291.9599 −8.95E−02 2.14E−01 1 Unchanged Low Q9UM44 188.5666 5.55E−01 −5.98E−01 1 Unchanged Low Q9UGC7 306.0797 −1.26E−01 3.22E−01 1 Unchanged Low P49146 181.9126 2.60E−01 −1.94E+00 1 Unchanged Low P54687 154.4299 1.36E+00 −1.41E−01 1 Unchanged Low O60884 321.0577 −3.12E−01 1.51E−01 1 Unchanged Low Q9NVC6 199.8392 5.40E−01 −2.84E−01 1 Unchanged Low O43399 299.1558 −9.06E−02 2.95E−01 1 Unchanged Low O75880 179.8238 7.65E−01 −4.28E−01 1 Unchanged Low P49406 398.6973 −1.12E+00 −7.10E−01 1 Unchanged Low Q9NYK5 396.3322 −8.27E−01 −7.61E−02 1 Unchanged Low O15428 233.6377 5.29E−01 4.25E−01 1 Unchanged Low O14842 219.8563 2.65E−01 −3.93E−01 1 Unchanged Low O15262 304.1323 1.33E−01 7.18E−01 1 Unchanged Low Q9NP61 262.4544 −3.66E−01 −9.76E−01 1 Unchanged Low O15491 292.4461 7.23E−02 4.80E−01 1 Unchanged Low O75390 412.1526 −1.29E+00 −1.07E+00 1 Unchanged Low P57088 331.588 −4.93E−01 −1.13E−01 1 Unchanged Low Q9NRY6 291.4542 −2.06E−02 2.96E−01 1 Unchanged Low O15403 242.0422 −5.18E−01 −2.39E+00 1 Unchanged Low Q9BPZ5 227.363 1.08E+00 1.17E+00 1 Unchanged Low P10301 262.4726 −2.26E−01 −6.24E−01 1 Unchanged Low 223.8166 6.79E−01 4.79E−01 1 Unchanged Low Q9P018 270.6564 4.58E−01 8.20E−01 1 Unchanged Low Q9Y4H2 298.8227 −1.35E−01 1.47E−01 1 Unchanged Low Q9UJX3 228.4449 3.64E−01 −4.10E−02 1 Unchanged Low Q9H5X0 304.1289 −3.01E−01 −1.15E−01 1 Unchanged Low Q92820 150.359 1.80E+00 3.70E−01 1 Unchanged Low Q9UKK3 352.9975 −3.10E−01 4.15E−01 1 Unchanged Low Q9NWC8 296.1206 −2.15E−01 −7.10E−02 1 Unchanged Low O14965 170.6789 9.67E−01 −4.69E−01 1 Unchanged Low P50613 327.4234 −7.56E−02 5.61E−01 1 Unchanged Low Q9H1C4 374.1085 −3.57E−01 5.22E−01 1 Unchanged Low P21851 328.1045 −3.14E−01 1.39E−01 1 Unchanged Low Q9UGJ0 413.4782 −6.42E−01 3.51E−01 1 Unchanged Low P04035 228.5315 1.70E−01 −5.20E−01 1 Unchanged Low Q9UKY7 396.2551 −1.23E+00 −1.24E+00 1 Unchanged Low O95478 247.5607 1.42E−01 −1.70E−01 1 Unchanged Low Q9Y3W9 275.7642 3.15E−01 5.94E−01 1 Unchanged Low Q9Y325 319.4542 −3.38E−01 −3.85E−02 1 Unchanged Low Q92854 266.8232 −3.20E−01 −9.02E−01 1 Unchanged Low P16106 200.5879 1.38E+00 1.07E+00 1 Unchanged Low O43143 345.6042 −5.86E−01 −2.41E−01 1 Unchanged Low Q13547 340.9663 −4.48E−01 −1.34E−02 1 Unchanged Low Q9H6F9 290.6336 −1.55E−01 −8.00E−02 1 Unchanged Low O9NX18 327.1007 −1.77E−01 3.38E−01 1 Unchanged Low O94764 266.5947 1.06E−01 6.24E−02 1 Unchanged Low P82909 293.6016 7.73E−02 3.94E−01 1 Unchanged Low Q9UI07 225.0966 4.66E−01 −4.00E−03 1 Unchanged Low P20337 205.8132 3.62E−01 −7.65E−01 1 Unchanged Low Q07960 237.9303 3.28E−01 −1.55E−02 1 Unchanged Low P49448 283.2713 −3.18E−01 −5.88E−01 1 Unchanged Low Q9NX48 457.1855 −8.35E−01 2.83E−01 1 Unchanged Low Q9NV56 173.6478 9.98E−01 −4.11E−01 1 Unchanged Low O00154 213.4547 6.77E−01 1.25E−01 1 Unchanged Low Q9UI70 311.4328 −1.49E−01 1.81E−01 1 Unchanged Low P26045 334.8518 −5.70E−01 −3.90E−01 1 Unchanged Low Q9Y2A8 147.0989 1.94E+00 3.38E−01 1 Unchanged Low Q9BZ89 223.0558 6.64E−01 2.99E−01 1 Unchanged Low P35052 221.7567 3.76E−01 −3.13E−01 1 Unchanged Low Q9H0S9 171.2074 1.80E+00 9.51E−01 1 Unchanged Low Q15654 260.4802 7.71E−02 −1.49E−01 1 Unchanged Low P51948 263.2799 2.22E−01 1.84E−01 1 Unchanged Low Q13133 272.0232 1.34E−02 −8.70E−02 1 Unchanged Low Q9P0J9 277.1331 −2.71E−01 −6.53E−01 1 Unchanged Low Q15546 170.0401 1.03E+00 −5.39E−01 1 Unchanged Low P28325 320.2206 −4.10E−01 −2.65E−01 1 Unchanged Low O94985 207.2587 1.03E+00 5.80E−01 1 Unchanged Low P48634 241.9692 7.23E−02 −5.80E−01 1 Unchanged Low Q9BRL6 268.4079 3.48E−01 4.65E−01 1 Unchanged Low O94851 187.2889 1.37E+00 6.64E−01 1 Unchanged Low Q9NW56 278.4551 2.25E−01 3.85E−01 1 Unchanged Low Q9H6X6 255.4932 6.17E−01 7.19E−01 1 Unchanged Low P41217 257.5072 −2.09E−01 −9.70E−01 1 Unchanged Low P31512 249.9252 5.50E−01 5.19E−01 1 Unchanged Low Q15425 206.4709 5.98E−01 −3.01E−01 1 Unchanged Low P40306 400.975 −5.34E−01 3.28E−01 1 Unchanged Low Q9NWZ8 238.3826 −2.85E−02 −9.82E−01 1 Unchanged Low P57073 251.002 4.77E−01 4.06E−01 1 Unchanged Low Q9Y450 274.9973 2.91E−01 4.34E−01 1 Unchanged Low P04062 322.2918 −6.43E−02 3.95E−01 1 Unchanged Low O75065 201.6823 7.50E−01 −1.22E−01 1 Unchanged Low Q9ULX2 259.9871 −2.72E−02 −4.71E−01 1 Unchanged Low Q99871 237.9086 4.62E−01 1.29E−01 1 Unchanged Low Q93065 345.3524 −6.12E−02 6.28E−01 1 Unchanged Low O43837 310.0846 −2.99E−01 −2.30E−01 1 Unchanged Low Q9H9L3 257.4051 4.37E−01 4.12E−01 1 Unchanged Low Q13740 256.0277 2.94E−01 1.28E−01 1 Unchanged Low Q12888 213.3434 1.09E+00 7.48E−01 1 Unchanged Low P78318 406.4772 −5.78E−01 2.71E−01 1 Unchanged Low P48436 275.3736 −2.81E−01 −8.10E−01 1 Unchanged Low P18065 284.4952 −1.22E−02 −2.05E−02 1 Unchanged Low Q9ULW6 218.587 3.52E−01 −5.92E−01 1 Unchanged Low O95154 294.419 −7.41E−02 −7.00E−03 1 Unchanged Low O95169 286.0758 −3.93E−01 −9.12E−01 1 Unchanged Low Q99982 154.8111 2.18E+00 8.82E−01 1 Unchanged Low Q99470 277.1416 3.08E−01 4.56E−01 1 Unchanged Low P16104 238.3532 2.80E−01 −2.68E−01 1 Unchanged Low Q9UG25 298.9147 4.21E−01 9.00E−01 1 Unchanged Low Q13158 276.784 1.21E−01 9.74E−02 1 Unchanged Low Q9NW32 302.6214 2.85E−01 7.17E−01 1 Unchanged Low O95153 224.5106 8.88E−01 5.75E−01 1 Unchanged Low Q9BQ73 265.3817 4.37E−01 4.85E−01 1 Unchanged Low Q15426 341.7927 −4.79E−02 5.71E−01 1 Unchanged Low Q92858 392.3029 −1.09E+00 −1.14E+00 1 Unchanged Low Q16849 162.9842 9.77E−01 −1.39E+00 1 Unchanged Low P11279 322.5735 −3.64E−01 −2.54E−01 1 Unchanged Low Q96II1 157.2667 1.47E+00 −3.63E−01 1 Unchanged Low P78504 296.4108 1.72E−01 4.43E−01 1 Unchanged Low O75937 282.0586 −3.71E−02 −1.62E−01 1 Unchanged Low O60575 194.1988 1.02E+00 1.00E−01 1 Unchanged Low Q9NYP7 257.9759 −5.42E−02 −6.81E−01 1 Unchanged Low O95436 317.3784 2.73E−01 8.34E−01 1 Unchanged Low O95324 277.0901 1.08E−01 3.94E−02 1 Unchanged Low Q9UQF6 410.9115 −8.47E−01 −2.89E−01 1 Unchanged Low P13010 239.8403 7.26E−01 5.51E−01 1 Unchanged Low Q9UJZ1 350.5499 −7.63E−01 −8.52E−01 1 Unchanged Low P50281 204.0657 1.19E+00 6.26E−01 1 Unchanged Low P15927 194.7022 1.54E+00 9.54E−01 1 Unchanged Low O75496 403.7854 −6.82E−01 −3.84E−02 1 Unchanged Low Q9P1E3 262.3787 3.25E−01 1.79E−01 1 Unchanged Low P40189 312.5572 −1.84E−01 −6.89E−02 1 Unchanged Low Q9Y259 331.557 −1.72E−01 1.93E−01 1 Unchanged Low O00633 226.7943 5.46E−01 −7.94E−02 1 Unchanged Low Q13432 229.0999 1.20E+00 1.08E+00 1 Unchanged Low Q9Y677 227.7917 6.43E−01 1.29E−01 1 Unchanged Low Q9BW24 234.5628 7.83E−01 4.97E−01 1 Unchanged Low Q9NSD9 246.1288 3.71E−01 −5.22E−02 1 Unchanged Low Q9NWQ0 482.328 −7.63E−01 4.00E−01 1 Unchanged Low Q9NWT6 363.8746 −8.29E−01 −9.18E−01 1 Unchanged Low Q9UPN3 478.6344 −9.75E−01 −3.78E−02 1 Unchanged Low Q96HW0 258.7634 1.22E+00 1.49E+00 1 Unchanged Low Q14257 249.8842 3.11E−01 −1.36E−01 1 Unchanged Low Q9NRJ5 316.91 −3.59E−01 −4.60E−01 1 Unchanged Low P23280 178.6789 1.11E+00 −4.28E−01 1 Unchanged Low Q14677 277.0019 −1.59E−01 −6.96E−01 1 Unchanged Low Q9Y394 375.1673 −6.67E−01 −3.97E−01 1 Unchanged Low Q9UKX5 173.978 1.58E+00 3.42E−01 1 Unchanged Low Q92539 264.3623 1.88E−01 −1.49E−01 1 Unchanged Low Q9NW01 199.1936 8.43E−01 −2.97E−01 1 Unchanged Low Q9NUW5 257.4882 3.82E−01 1.11E−01 1 Unchanged Low Q9BYC4 394.9285 −6.86E−01 −2.31E−01 1 Unchanged Low P02545 433.306 −1.25E+00 −1.27E+00 1 Unchanged Low O60585 315.9302 −9.45E−02 5.68E−02 1 Unchanged Low P23458 375.1408 −3.71E−01 1.95E−01 1 Unchanged Low Q9BY13 401.4116 −5.44E−01 1.14E−01 1 Unchanged Low Q9UBC2 247.3586 7.96E−01 6.59E−01 1 Unchanged Low O76022 266.0871 2.17E−01 −8.34E−02 1 Unchanged Low P33993 234.4011 3.22E−01 −5.33E−01 1 Unchanged Low Q92963 415.4004 −5.76E−01 1.58E−01 1 Unchanged Low Q9HAF1 328.0993 1.50E−01 6.13E−01 1 Unchanged Low Q9NZ36 379.485 −7.53E−01 −6.05E−01 1 Unchanged Low Q9BQQ3 283.9342 5.27E−01 7.20E−01 1 Unchanged Low O95214 337.2896 3.87E−02 5.19E−01 1 Unchanged Low Q9Y294 237.0749 8.54E−01 5.47E−01 1 Unchanged Low O95810 284.3868 1.06E−01 −4.11E−02 1 Unchanged Low P30670 412.6188 −6.41E−01 −1.59E−02 1 Unchanged Low P51946 242.2819 7.43E−01 4.38E−01 1 Unchanged Low Q15290 315.4543 1.74E−02 2.12E−01 1 Unchanged Low Q9NX11 219.2418 8.69E−01 2.02E−01 1 Unchanged Low Q9P0S3 239.5316 6.91E−01 2.90E−01 1 Unchanged Low P04554 352.4183 −3.79E−01 −1.20E−01 1 Unchanged Low O15243 340.9139 −1.22E−01 2.47E−01 1 Unchanged Low O43717 317.004 9.07E−02 3.54E−01 1 Unchanged Low O95876 233.8891 8.11E−01 3.88E−01 1 Unchanged Low Q9H8D5 246.7925 2.96E−01 −3.81E−01 1 Unchanged Low Q9Y3B6 361.6747 −7.01E−01 −7.80E−01 1 Unchanged Low Q9P0S7 195.3392 1.09E+00 −4.11E−02 1 Unchanged Low O60630 278.4627 −3.14E−02 −4.93E−01 1 Unchanged Low O95285 349.7511 −1.28E−01 3.14E−01 1 Unchanged Low Q08945 289.639 −1.37E−01 −5.48E−01 1 Unchanged Low O43583 253.5145 5.86E−01 3.17E−01 1 Unchanged Low O95149 248.5641 7.05E−01 4.41E−01 1 Unchanged Low Q9HAS8 293.0254 3.26E−01 4.44E−01 1 Unchanged Low Q9BQ39 233.2592 3.82E−01 −5.49E−01 1 Unchanged Low O15304 182.3257 1.78E+00 7.83E−01 1 Unchanged Low Q15394 345.6465 −1.88E−01 1.42E−01 1 Unchanged Low Q9NZA3 284.2776 3.79E−01 4.07E−01 1 Unchanged Low P26022 154.9189 1.65E+00 −6.72E−01 1 Unchanged Low Q00536 318.5577 7.68E−02 3.09E−01 1 Unchanged Low Q9UMW5 197.6582 2.55E+00 2.16E+00 1 Unchanged Low O95353 203.4709 1.68E+00 1.12E+00 1 Unchanged Low O95808 240.0311 7.11E−01 2.60E−01 1 Unchanged Low Q9BXJ8 455.5065 −4.18E−01 6.50E−01 1 Unchanged Low P36776 354.6324 −3.40E−01 −9.78E−02 1 Unchanged Low Q9BUR9 299.1204 3.03E−01 4.35E−01 1 Unchanged Low Q9Y3R1 224.7776 9.58E−01 3.78E−01 1 Unchanged Low Q92997 284.6254 3.65E−01 3.43E−01 1 Unchanged Low O14682 274.7193 −7.50E−02 −7.90E−01 1 Unchanged Low Q9Y255 432.9739 −7.86E−01 −2.30E−01 1 Unchanged Low Q16664 316.9703 −1.92E−01 −3.09E−01 1 Unchanged Low P31943 416.9005 −1.15E+00 −1.46E+00 1 Unchanged Low P49848 198.2917 1.04E+00 −1.87E−01 1 Unchanged Low Q04984 325.4422 −1.20E−01 −4.81E−02 1 Unchanged Low P20719 302.8287 1.98E−01 2.63E−01 1 Unchanged Low Q9H5Y0 313.8457 −6.25E−02 −9.24E−02 1 Unchanged Low P19021 268.0943 5.06E−01 3.13E−01 1 Unchanged Low Q92544 296.5662 2.04E−01 1.80E−01 1 Unchanged Low Q12907 282.474 −2.70E−03 −4.97E−01 1 Unchanged Low Q9BW91 324.483 −1.48E−01 −1.39E−01 1 Unchanged Low P53365 318.382 9.37E−02 2.51E−01 1 Unchanged Low P35869 326.5306 3.27E−01 7.40E−01 1 Unchanged Low Q13145 470.7589 −6.46E−01 3.08E−01 1 Unchanged Low O14747 370.593 −1.51E−01 3.69E−01 1 Unchanged Low Q9GZT5 334.369 −2.05E−01 −1.46E−01 1 Unchanged Low P08174 492.3204 −1.17E+00 −6.26E−01 1 Unchanged Low Q9H689 282.3328 3.77E−01 2.65E−01 1 Unchanged Low Q9P0T7 301.4061 2.40E−01 2.82E−01 1 Unchanged Low Q9H2V7 328.1261 1.88E−01 5.13E−01 1 Unchanged Low Q9NWT0 407.636 −4.19E−01 2.13E−01 1 Unchanged Low Q9Y6X2 233.7882 1.08E+00 6.71E−01 1 Unchanged Low Q9P1P1 355.1102 −4.15E−01 −3.46E−01 1 Unchanged Low P23919 174.3854 1.35E+00 −5.53E−01 1 Unchanged Low P37140 391.3748 −1.69E−01 5.03E−01 1 Unchanged Low Q9NW54 472.8474 −4.53E−01 6.33E−01 1 Unchanged Low Q9UMS0 400.6081 −6.74E−01 −4.00E−01 1 Unchanged Low P14207 235.1893 4.24E−01 −6.13E−01 1 Unchanged Low Q9UHC7 267.5313 3.76E−01 −7.36E−03 1 Unchanged Low O75844 276.2357 −9.63E−02 −9.58E−01 1 Unchanged Low 162.8523 1.86E+00 −3.90E−02 1 Unchanged Low P16587 369.9292 −4.86E−01 −3.52E−01 1 Unchanged Low Q9NVY2 378.7795 −4.06E−01 −7.72E−02 1 Unchanged Low Q9Y3I1 369.3121 −2.15E−01 1.93E−01 1 Unchanged Low Q9H320 271.2531 1.11E+00 1.24E+00 1 Unchanged Low P49903 364.5082 −4.50E−02 4.37E−01 1 Unchanged Low O00506 289.4017 2.22E−01 7.86E−03 1 Unchanged Low O00273 350.0198 −4.16E−02 2.87E−01 1 Unchanged Low Q08170 247.9554 4.68E−01 −2.61E−01 1 Unchanged Low Q9Y3B8 240.8904 1.41E+00 1.22E+00 1 Unchanged Low Q9P0N0 362.9626 −2.38E−01 5.03E−02 1 Unchanged Low Q9BRI3 361.6895 −2.21E−01 6.60E−02 1 Unchanged Low Q9Y319 183.4471 1.58E+00 1.97E−01 1 Unchanged Low Q16514 246.9777 1.46E+00 1.38E+00 1 Unchanged Low P13489 259.1076 5.18E−01 5.00E−02 1 Unchanged Low Q99987 240.3908 6.42E−01 −8.59E−02 1 Unchanged Low P56181 358.4382 −4.37E−01 −4.48E−01 1 Unchanged Low P51148 336.6203 −3.64E−02 1.20E−01 1 Unchanged Low Q9HD34 276.3612 3.22E−01 −5.12E−02 1 Unchanged Low Q9HAN2 313.4126 1.43E−01 1.58E−01 1 Unchanged Low P08107 413.3803 −7.31E−01 −4.87E−01 1 Unchanged Low O60499 272.2579 7.66E−01 6.81E−01 1 Unchanged Low Q9HBL3 237.4707 9.68E−01 4.38E−01 1 Unchanged Low Q9BSJB 482.4222 −7.63E−01 6.53E−02 1 Unchanged Low O60838 264.8237 5.87E−01 2.33E−01 1 Unchanged Low Q98TM6 343.6429 −1.97E−01 −1.53E−01 1 Unchanged Low Q9H4L0 147.5387 2.78E+00 5.77E−01 1 Unchanged Low P50402 316.6654 1.47E−02 −8.04E−02 1 Unchanged Low Q9NZP7 299.844 −4.98E−02 −4.94E−01 1 Unchanged Low P49116 281.6482 1.36E−01 −4.03E−01 1 Unchanged Low P11234 444.9874 −7.97E−01 −3.51E−01 1 Unchanged Low P15408 342.8236 2.94E−01 7.18E−01 1 Unchanged Low Q9P1Q8 312.2142 −1.33E−01 −5.03E−01 1 Unchanged Low P39060 230.0488 1.11E+00 4.81E−01 1 Unchanged Low Q9Y2N3 319.0933 −2.13E−01 −5.91E−01 1 Unchanged Low P02749 320.758 −3.21E−01 −8.52E−01 1 Unchanged Low Q9P189 359.0228 −2.62E−01 −1.34E−01 1 Unchanged Low O43822 291.7148 3.91E−01 2.50E−01 1 Unchanged Low Q9UNZ2 420.0654 −3.35E−01 3.27E−01 1 Unchanged Low Q9Y4G5 376.7971 −2.00E−01 1.77E−01 1 Unchanged Low Q13310 327.507 5.03E−02 9.11E−02 1 Unchanged Low P45974 304.4284 2.95E−01 2.39E−01 1 Unchanged Low P55317 302.8162 2.65E−01 1.60E−01 1 Unchanged Low O43364 435.9554 −6.35E−01 −1.28E−01 1 Unchanged Low P55345 333.8774 −1.47E−01 −2.48E−01 1 Unchanged Low P48230 437.5376 −7.73E−01 −4.40E−01 1 Unchanged Low Q9BUY3 264.7192 9.91E−01 8.34E−01 1 Unchanged Low O00115 326.0947 2.66E−01 4.34E−01 1 Unchanged Low O43318 254.8269 8.26E−01 4.01E−01 1 Unchanged Low O95572 287.175 3.91E−01 1.33E−01 1 Unchanged Low P35080 176.518 1.58E+00 −3.76E−01 1 Unchanged Low Q9NW29 241.9521 6.00E−01 −3.40E−01 1 Unchanged Low Q9NZE9 299.9861 6.01E−01 6.64E−01 1 Unchanged Low Q9BYV2 C 390.6938 −5.83E−01 −5.66E−01 1 Unchanged Low Q9UJX4 280.1684 4.97E−01 1.81E−01 1 Unchanged Low O00302 347.7981 3.31E−02 2.22E−01 1 Unchanged Low Q92886 302.7027 2.07E−01 −3.76E−02 1 Unchanged Low O14929 270.1111 −4.02E−02 −1.41E+00 1 Unchanged Low Q9NVK7 301.1995 2.54E−01 2.92E−02 1 Unchanged Low Q9UBN0 329.7234 1.14E−01 1.50E−01 1 Unchanged Low O43611 245.5832 8.94E−01 2.80E−01 1 Unchanged Low O94777 291.5641 1.95E−01 −2.71E−01 1 Unchanged Low Q14669 406.8782 −5.31E−01 −2.96E−01 1 Unchanged Low Q9NUR0 168.9127 2.42E+00 7.56E−01 1 Unchanged Low Q16822 251.8272 3.61E−01 −7.52E−01 1 Unchanged Low Q9Y640 257.3848 6.48E−01 2.92E−02 1 Unchanged Low P48595 269.7194 2.44E+00 2.72E+00 1 Unchanged Low P26639 371.5003 −7.20E−02 2.47E−01 1 Unchanged Low P29597 268.5377 6.92E−01 3.02E−01 1 Unchanged Low O60671 210.3983 8.49E−01 −8.59E−01 1 Unchanged Low Q9NW97 379.0815 3.71E−01 1.03E+00 1 Unchanged Low Q9P027 439.5495 −8.60E−01 −7.62E−01 1 Unchanged Low O95772 254.0574 7.93E−01 2.12E−01 1 Unchanged Low Q9NR28 384.7351 3.24E−01 1.00E+00 1 Unchanged Low P11413 244.4906 3.98E−01 −9.31E−01 1 Unchanged Low Q99567 375.0149 −4.48E−01 −5.38E−01 1 Unchanged Low Q9BZR9 315.1764 7.20E−01 9.45E−01 1 Unchanged Low O43632 330.4468 5.81E−02 −2.73E−02 1 Unchanged Low Q9Y305 421.5064 −3.91E−01 8.49E−02 1 Unchanged Low P17096 333.78 −2.04E−01 −5.62E−01 1 Unchanged Low P28677 272.797 5.38E−01 3.76E−02 1 Unchanged Low Q9UBX5 176.4964 2.10E+00 4.44E−01 1 Unchanged Low Q9Y304 301.8585 6.87E−02 −4.56E−01 1 Unchanged Low O15379 306.8418 7.90E−01 9.41E−01 1 Unchanged Low Q02790 302.2597 8.58E−02 −4.33E−01 1 Unchanged Low Q9H240 393.3189 3.44E−01 1.06E+00 1 Unchanged Low O76095 274.4316 4.42E−01 −1.56E−01 1 Unchanged Low Q9Y5Q8 404.6602 −6.66E−01 −7.50E−01 1 Unchanged Low Q9NNW5 322.3381 4.37E−01 5.37E−01 1 Unchanged Low P01121 296.4811 5.09E−01 3.29E−01 1 Unchanged Low Q9H0V7 405.6684 −7.23E−01 −9.00E−01 1 Unchanged Low O60664 365.5782 −5.94E−01 −1.16E+00 1 Unchanged Low P56554 378.959 −1.18E−01 1.57E−01 1 Unchanged Low O00330 373.6892 −2.99E−03 3.14E−01 1 Unchanged Low O60784 342.086 −7.76E−02 −2.02E−01 1 Unchanged Low Q9NQZ0 491.0715 −1.19E+00 −1.22E+00 1 Unchanged Low P52790 345.2169 4.07E−01 7.21E−01 1 Unchanged Low P52815 285.7775 5.61E−01 2.43E−01 1 Unchanged Low O14983 245.4613 1.05E+00 4.12E−01 1 Unchanged Low P04259 428.9832 −6.20E−01 −3.99E−01 1 Unchanged Low P16455 318.0812 2.19E−01 3.81E−02 1 Unchanged Low Q9Y5L9 273.2945 2.87E−01 −6.13E−01 1 Unchanged Low P41214 297.4677 5.56E−01 3.72E−01 1 Unchanged Low Q9H6U4 314.4039 −2.65E−01 −1.26E+00 1 Unchanged Low Q15393 277.0735 5.30E−01 −1.59E−02 1 Unchanged Low P55055 347.7942 1.03E−01 1.76E−01 1 Unchanged Low P51805 345.4093 2.10E−01 3.36E−01 1 Unchanged Low O75815 297.768 4.94E−01 2.34E−01 1 Unchanged Low Q9Y2Y9 319.2905 5.42E−01 6.00E−01 1 Unchanged Low Q99633 368.1886 −2.05E−01 −2.18E−01 1 Unchanged Low P05155 329.7432 2.13E−01 1.41E−01 1 Unchanged Low Q9UN50 333.1657 1.27E−01 1.84E−02 1 Unchanged Low Q14011 352.0144 2.66E−01 4.94E−01 1 Unchanged Low O75807 458.6852 −7.67E−02 8.10E−01 1 Unchanged Low Q14457 466.4393 −6.18E−02 8.80E−01 1 Unchanged Low Q02818 298.8382 9.39E−02 −6.39E−01 1 Unchanged Low O15235 391.6738 −7.66E−03 3.94E−01 1 Unchanged Low Q9Y3E0 275.4907 1.21E+00 1.07E+00 1 Unchanged Low Q9NQZ5 303.5369 3.51E−01 1.19E−02 1 Unchanged Low Q9UHW4 303.9535 4.06E−01 1.25E−01 1 Unchanged Low P82914 405.0567 −3.25E−01 −9.27E−02 1 Unchanged Low P25787 437.9448 −2.86E−01 2.80E−01 1 Unchanged Low P26447 275.5734 8.38E−01 4.57E−01 1 Unchanged Low Q9Y605 373.9359 −2.11E−01 −2.10E−01 1 Unchanged Low Q14776 276.788 8.15E−01 4.34E−01 1 Unchanged Low P30837 479.1158 −8.27E−01 −4.86E−01 1 Unchanged Low P09668 460.5856 −3.69E−01 2.92E−01 1 Unchanged Low Q02313 383.4797 −1.73E−01 −4.02E−02 1 Unchanged Low Q13148 344.328 1.47E−01 1.31E−01 1 Unchanged Low Q16645 353.4204 7.21E−01 1.17E+00 1 Unchanged Low 168.643 2.20E+00 −1.24E−01 1 Unchanged Low P57739 261.2968 9.26E−01 3.41E−01 1 Unchanged Low O60568 319.8117 1.05E−01 −3.04E−01 1 Unchanged Low Q9HAU4 482.7167 −2.51E−01 6.44E−01 1 Unchanged Low P49914 312.027 7.38E−02 −5.17E−01 1 Unchanged Low O60510 265.2168 1.06E+00 6.26E−01 1 Unchanged Low Q9BX68 308.6409 7.92E−01 7.99E−01 1 Unchanged Low P29084 281.687 4.57E−01 −2.17E−01 1 Unchanged Low P09526 344.9493 1.64E−01 1.49E−01 1 Unchanged Low O15471 279.8225 7.09E−01 2.44E−01 1 Unchanged Low Q9UEE9 242.684 1.54E+00 9.79E−01 1 Unchanged Low Q15011 298.5074 2.94E−02 −9.43E−01 1 Unchanged Low Q9BWG8 244.6389 1.08E+00 2.57E−01 1 Unchanged Low Q9Y397 428.8727 −2.58E−01 1.99E−01 1 Unchanged Low Q14596 355.7499 2.54E−01 4.08E−01 1 Unchanged Low P23497 394.8464 1.25E−01 5.64E−01 1 Unchanged Low Q16633 188.1549 1.81E+00 −5.39E−02 1 Unchanged Low Q99961 280.235 6.51E−01 9.47E−02 1 Unchanged Low Q07021 345.9018 −3.77E−01 −1.22E+00 1 Unchanged Low Q16513 490.5792 −5.83E−01 3.97E−02 1 Unchanged Low Q9H070 331.9695 4.61E−02 −3.46E−01 1 Unchanged Low Q13227 424.6909 −6.12E−01 −6.65E−01 1 Unchanged Low P20339 478.1731 −1.46E−01 7.15E−01 1 Unchanged Low Q9NXX4 255.5867 1.24E+00 6.61E−01 1 Unchanged Low Q92900 336.7297 1.58E−01 −5.69E−02 1 Unchanged Low Q9H2K4 240.051 8.83E−01 −3.58E−01 1 Unchanged Low O14917 309.398 5.50E−01 3.13E−01 1 Unchanged Low Q9NZ88 309.7781 8.79E−01 8.60E−01 1 Unchanged Low Q9BYC8 351.4981 5.13E−01 7.33E−01 1 Unchanged Low Q15311 358.3107 3.19E−01 4.76E−01 1 Unchanged Low Q9NWE9 402.6031 −3.02E−01 −2.50E−01 1 Unchanged Low O95571 425.0962 −1.06E−01 3.50E−01 1 Unchanged Low P36941 409.094 −1.23E−01 1.72E−01 1 Unchanged Low P49790 317.116 4.85E−01 2.58E−01 1 Unchanged Low Q99607 302.1703 4.75E−01 4.79E−03 1 Unchanged Low Q9UIV1 345.9619 8.86E−01 1.21E+00 1 Unchanged Low Q9Y3E4 247.1535 1.79E+00 1.29E+00 1 Unchanged Low P19367 366.4437 −4.61E−01 −1.25E+00 1 Unchanged Low Q14250 272.9152 6.99E−01 −7.52E−02 1 Unchanged Low Q9UL33 450.4535 1.18E−01 8.90E−01 1 Unchanged Low Q15019 378.666 −3.91E−01 −8.36E−01 1 Unchanged Low Q13084 357.6504 −1.77E−01 −6.01E−01 1 Unchanged Low Q9UMR2 393.1434 −4.04E−02 1.40E−01 1 Unchanged Low P55855 424.0867 −2.84E−01 −3.58E−02 1 Unchanged Low Q13155 368.4293 2.12E−01 3.42E−01 1 Unchanged Low P78371 428.2475 −3.62E−01 −1.60E−01 1 Unchanged Low P08173 444.3189 −2.47E−01 2.11E−01 1 Unchanged Low O60478 362.4989 4.47E−01 6.73E−01 1 Unchanged Low O60429 258.282 1.39E+00 8.47E−01 1 Unchanged Low O75935 405.4281 −1.25E−01 7.97E−02 1 Unchanged Low Q13147 307.9098 3.28E−01 −2.63E−01 1 Unchanged Low Q9NPH4 295.4166 8.60E−01 5.45E−01 1 Unchanged Low Q9UJ96 468.9343 −6.30E−01 −3.80E−01 1 Unchanged Low P17081 362.2816 3.61E−01 5.09E−01 1 Unchanged Low P11166 373.8343 9.84E−02 1.61E−01 1 Unchanged Low Q14820 389.2167 −2.30E−02 9.19E−02 1 Unchanged Low Q92935 437.6869 −8.08E−01 −1.26E+00 1 Unchanged Low P31749 355.1851 −3.24E−02 −3.46E−01 1 Unchanged Low Q13454 355.5691 2.06E−01 1.50E−01 1 Unchanged Low P35520 172.0203 2.41E+00 −5.72E−02 1 Unchanged Low P53602 412.6357 −8.51E−01 −1.94E+00 1 Unchanged Low Q9H7G3 306.3867 1.81E−01 −6.86E−01 1 Unchanged Low Q13123 358.3456 5.53E−01 7.69E−01 1 Unchanged Low O14744 378.8177 1.21E−01 2.37E−01 1 Unchanged Low Q9Y566 290.0718 8.59E−01 4.27E−01 1 Unchanged Low Q9BUJ9 412.4352 −1.79E−02 2.94E−01 1 Unchanged Low P51790 315.7621 2.04E−01 −4.80E−01 1 Unchanged Low O14547 291.9777 6.71E−01 1.01E−01 1 Unchanged Low Q99753 345.0384 5.66E−01 6.27E−01 1 Unchanged Low Q9NQC8 280.7773 1.04E+00 5.75E−01 1 Unchanged Low O43919 230.823 8.83E−01 −9.82E−01 1 Unchanged Low P78345 411.2575 2.46E−01 7.21E−01 1 Unchanged Low P54257 384.9948 −2.35E−01 −4.83E−01 1 Unchanged Low Q9Y3F4 369.3734 −3.11E−02 −2.25E−01 1 Unchanged Low P29536 311.936 1.57E−01 −7.13E−01 1 Unchanged Low O75925 471.2944 −1.44E−01 5.15E−01 1 Unchanged Low Q9UMX5 345.2233 1.57E−01 −1.71E−01 1 Unchanged Low Q9UMZ9 337.1554 1.42E−01 −3.28E−01 1 Unchanged Low Q92905 345.1985 5.84E−01 6.06E−01 1 Unchanged Low Q9NSD7 466.2798 −9.26E−01 −1.40E+00 1 Unchanged Low Q9P2W3 179.6321 2.45E+00 2.04E−01 1 Unchanged Low Q9BVI7 424.8293 7.34E−02 4.99E−01 1 Unchanged Low Q9Y4L1 390.9975 −9.20E−02 −1.49E−01 1 Unchanged Low Q02363 410.6421 −3.20E−01 −4.33E−01 1 Unchanged Low Q9Y5J8 456.8557 −1.81E−01 2.99E−01 1 Unchanged Low 446.2248 −3.57E−01 −1.50E−01 1 Unchanged Low Q99501 429.6515 1.15E−01 5.84E−01 1 Unchanged Low Q00613 376.2292 1.01E−01 4.71E−02 1 Unchanged Low Q9H5Z1 217.0007 1.51E+00 −1.35E−01 1 Unchanged Low P09661 315.5701 −1.77E−01 −1.94E+00 1 Unchanged Low P54709 416.5779 −1.20E−01 2.22E−02 1 Unchanged Low P13164 231.1336 3.12E+00 2.50E+00 1 Unchanged Low Q9Y6E2 361.6248 2.50E−01 1.37E−01 1 Unchanged Low Q9NVG2 436.0959 1.28E−01 6.34E−01 1 Unchanged Low P27448 386.4633 −1.97E−02 −1.08E−01 1 Unchanged Low O15438 499.6643 −6.54E−01 −3.40E−01 1 Unchanged Low Q9UL48 261.8209 1.16E+00 2.88E−01 1 Unchanged Low O94763 420.3384 2.40E−01 6.77E−01 1 Unchanged Low Q13190 269.5995 1.13E+00 3.89E−01 1 Unchanged Low Q13122 383.7948 4.94E−02 −2.22E−02 1 Unchanged Low O75312 388.3905 1.79E−01 2.74E−01 1 Unchanged Low P37837 373.7275 −1.30E−02 −2.92E−01 1 Unchanged Low O75762 327.3962 8.28E−01 7.06E−01 1 Unchanged Low Q99969 312.0672 4.82E−01 −1.44E−01 1 Unchanged Low Q9UNP2 227.7665 1.41E+00 −1.15E−01 1 Unchanged Low P56524 342.9334 2.73E−01 −1.17E−01 1 Unchanged Low Q9H644 255.3931 1.49E+00 6.93E−01 1 Unchanged Low Q13627 407.7774 −3.27E−01 −6.06E−01 1 Unchanged Low Q03405 431.3524 −3.29E−01 −3.38E−01 1 Unchanged Low Q9NPQ8 404.6217 9.57E−02 2.48E−01 1 Unchanged Low Q15375 310.569 7.13E−01 2.55E−01 1 Unchanged Low P05114 291.2748 1.02E+00 4.99E−01 1 Unchanged Low Q9UKU4 422.4244 1.07E−01 4.23E−01 1 Unchanged Low P08195 395.768 −1.47E−01 −3.58E−01 1 Unchanged Low Q15545 442.5426 1.59E−03 3.92E−01 1 Unchanged Low 290.8781 7.04E−01 −1.31E−01 1 Unchanged Low Q05397 410.2909 4.23E−02 1.73E−01 1 Unchanged Low Q9Y6G1 439.8467 −1.15E−01 1.53E−01 1 Unchanged Low P41212 406.6035 3.48E−01 6.70E−01 1 Unchanged Low O14737 443.7457 −3.10E−01 −2.13E−01 1 Unchanged Low Q9UHB9 287.2236 9.21E−01 2.16E−01 1 Unchanged Low Q96D21 427.9499 2.36E−02 2.94E−01 1 Unchanged Low Q9Y4I1 375.8247 1.15E−01 −7.23E−02 1 Unchanged Low Q9Y5L4 354.9111 4.70E−01 3.39E−01 1 Unchanged Low O75439 367.0789 −3.42E−01 −1.48E+00 1 Unchanged Low P55010 376.3076 −7.62E−02 −5.31E−01 1 Unchanged Low Q9BY44 420.1404 −1.60E−01 −1.78E−01 1 Unchanged Low Q13164 290.5304 9.58E−01 2.93E−01 1 Unchanged Low P53667 386.0829 1.77E−01 1.26E−01 1 Unchanged Low Q9UNH6 427.3762 −2.38E−01 −2.78E−01 1 Unchanged Low O00258 415.5431 2.63E−01 5.60E−01 1 Unchanged Low Q9Y3I0 470.3717 −1.70E−01 2.52E−01 1 Unchanged Low Q9Y368 226.9908 1.83E+00 4.80E−01 1 Unchanged Low P14866 374.6383 −1.19E−01 −6.92E−01 1 Unchanged Low Q13885 420.8456 −1.14E−01 −9.41E−02 1 Unchanged Low O43765 408.6939 1.09E−01 2.10E−01 1 Unchanged Low O14632 446.1081 5.18E−02 4.40E−01 1 Unchanged Low P31939 432.286 −2.92E−01 −3.76E−01 1 Unchanged Low P28331 438.7901 −2.61E−01 −2.35E−01 1 Unchanged Low P41970 325.3706 9.96E−01 8.03E−01 1 Unchanged Low Q92973 346.1733 6.20E−02 −7.51E−01 1 Unchanged Low P36507 414.6953 5.79E−02 1.46E−01 1 Unchanged Low Q16512 451.4528 −1.48E−01 9.18E−02 1 Unchanged Low O43447 271.0162 1.20E+00 3.05E−01 1 Unchanged Low P30040 351.5665 2.50E−01 −2.29E−01 1 Unchanged Low O95399 410.4914 −1.30E−01 −3.04E−01 1 Unchanged Low 401.0113 −2.74E−01 −7.87E−01 1 Unchanged Low Q12792 418.007 −2.05E−01 −3.87E−01 1 Unchanged Low Q14318 435.6453 −1.58E−01 −9.35E−02 1 Unchanged Low O75955 343.496 4.47E−01 2.68E−02 1 Unchanged Low Q9BVY8 440.9559 −2.37E−01 −2.35E−01 1 Unchanged Low Q16288 243.0358 1.72E+00 5.53E−01 1 Unchanged Low O75380 426.4999 −1.10E−01 −1.21E−01 1 Unchanged Low Q9BY51 400.0464 −4.04E−02 −2.80E−01 1 Unchanged Low Q9BVK3 422.5145 −1.47E−01 −2.56E−01 1 Unchanged Low Q9P0N3 281.424 1.60E+00 1.07E+00 1 Unchanged Low P24534 364.5026 2.68E−01 −8.11E−02 1 Unchanged Low P49336 375.2575 −2.82E−02 −6.00E−01 1 Unchanged Low P34130 323.0643 3.54E−01 −5.53E−01 1 Unchanged Low O75425 366.1692 3.01E−01 −7.34E−03 1 Unchanged Low Q15293 304.1243 7.99E−01 5.01E−02 1 Unchanged Low O95376 332.2465 7.28E−01 3.41E−01 1 Unchanged Low O75489 375.1108 1.69E−01 −1.99E−01 1 Unchanged Low P28482 456.1064 −2.25E−01 −1.28E−01 1 Unchanged Low P20823 424.3654 3.93E−01 7.09E−01 1 Unchanged Low O15250 496.7532 −3.09E−01 4.57E−02 1 Unchanged Low P55769 346.68 1.63E+00 1.80E+00 1 Unchanged Low O94817 485.9574 −5.74E−01 −8.52E−01 1 Unchanged Low O75352 406.7998 6.41E−01 9.41E−01 1 Unchanged Low Q16585 324.9166 7.31E−01 1.96E−01 1 Unchanged Low Q9H7X7 383.5805 6.99E−01 8.23E−01 1 Unchanged Low O15173 321.6602 5.29E−01 −2.74E−01 1 Unchanged Low Q9GZX9 219.3062 2.33E+00 7.99E−01 1 Unchanged Low Q16594 372.6331 1.32E+00 1.60E+00 1 Unchanged Low O00479 348.9168 6.84E−01 4.15E−01 1 Unchanged Low P54760 456.4179 −3.08E−01 −3.55E−01 1 Unchanged Low P25490 479.4548 −1.72E−01 1.39E−01 1 Unchanged Low Q9UJY0 454.8441 −2.44E−01 −2.31E−01 1 Unchanged Low Q09666 406.041 1.24E−01 2.41E−02 1 Unchanged Low O15305 411.2528 3.98E−01 5.63E−01 1 Unchanged Low O60492 343.3316 1.42E−01 −8.68E−01 1 Unchanged Low Q9UND3 340.6147 6.10E−01 1.54E−01 1 Unchanged Low Q9HB15 436.9131 −1.43E−01 −2.14E−01 1 Unchanged Low Q9Y3B4 350.4808 5.61E−01 1.87E−01 1 Unchanged Low Q14107 407.3091 1.52E−01 6.52E−02 1 Unchanged Low P52435 472.7272 −2.94E−01 −1.93E−01 1 Unchanged Low Q9Y262 444.385 −4.58E−01 −9.28E−01 1 Unchanged Low P10163 401.2036 −2.74E−01 −1.05E+00 1 Unchanged Low P38378 478.7225 −5.57E−01 −7.86E−01 1 Unchanged Low P48735 456.8577 −4.74E−01 −8.28E−01 1 Unchanged Low Q9NPF5 421.964 −6.26E−02 −2.41E−01 1 Unchanged Low O14616 324.9789 1.15E+00 8.38E−01 1 Unchanged Low Q00839 419.7665 5.44E−02 −2.18E−02 1 Unchanged Low O95563 404.2972 1.47E−01 −5.96E−03 1 Unchanged Low Q92974 233.2947 1.61E+00 −1.95E−01 1 Unchanged Low Q9UEE5 434.4129 1.24E−01 2.46E−01 1 Unchanged Low Q9NX81 271.6819 1.31E+00 2.33E−01 1 Unchanged Low Q9NXF9 421.54 −1.37E−01 −4.38E−01 1 Unchanged Low P98171 345.0241 2.39E−01 −6.77E−01 1 Unchanged Low P56192 331.1505 7.29E−01 1.63E−01 1 Unchanged Low O95411 326.6136 9.02E−01 4.10E−01 1 Unchanged Low P09132 419.7603 9.38E−01 1.38E+00 1 Unchanged Low Q92537 319.914 5.86E−01 −3.30E−01 1 Unchanged Low P49761 486.0405 −6.88E−02 2.91E−01 1 Unchanged Low Q9HDC4 391.3835 3.41E−01 1.62E−01 1 Unchanged Low P98160 439.0897 −2.01E−01 −4.44E−01 1 Unchanged Low Q9NQV6 441.3923 2.55E−01 4.79E−01 1 Unchanged Low Q9NRX6 370.1383 4.42E−01 8.82E−02 1 Unchanged Low O76084 374.6479 −9.29E−02 −1.16E+00 1 Unchanged Low P23197 428.3076 −1.22E−01 −4.09E−01 1 Unchanged Low Q99439 391.978 4.38E−02 −4.96E−01 1 Unchanged Low O14656 463.6417 9.27E−02 3.59E−01 1 Unchanged Low Q9NPJ3 428.1718 1.09E−01 6.55E−02 1 Unchanged Low P41226 361.2685 5.70E−01 1.95E−01 1 Unchanged Low Q9Y478 304.7576 5.35E−01 −8.93E−01 1 Unchanged Low 348.2928 3.45E−01 −4.73E−01 1 Unchanged Low Q12904 426.5346 2.50E−01 2.94E−01 1 Unchanged Low P20264 402.9521 −3.44E−02 −6.02E−01 1 Unchanged Low Q15428 355.7289 6.60E−01 2.36E−01 1 Unchanged Low P49771 439.4747 7.84E−03 −1.10E−01 1 Unchanged Low P49005 349.3417 3.16E−01 −6.49E−01 1 Unchanged Low Q99879 420.7323 4.74E−01 5.69E−01 1 Unchanged Low P49821 452.5721 −1.70E−01 −3.86E−01 1 Unchanged Low P10644 464.5909 1.12E−01 3.00E−01 1 Unchanged Low Q9Y5J4 301.448 1.64E+00 1.06E+00 1 Unchanged Low P31040 492.7974 −5.57E−01 −9.36E−01 1 Unchanged Low Q9UHA2 458.4094 5.73E−02 1.30E−01 1 Unchanged Low Q9UBF6 390.7196 5.34E−01 3.40E−01 1 Unchanged Low Q9Y5S2 430.2759 2.40E−01 2.08E−01 1 Unchanged Low P20809 332.3748 1.99E−01 −1.51E+00 1 Unchanged Low Q13526 417.3666 4.59E−01 4.66E−01 1 Unchanged Low Q9NWQ9 488.6936 8.93E−02 4.22E−01 1 Unchanged Low Q9Y6J0 350.127 −4.84E−02 −2.02E+00 1 Unchanged Low Q9Y4Z6 283.3006 1.99E+00 1.26E+00 1 Unchanged Low Q01433 400.6864 3.82E−01 1.47E−01 1 Unchanged Low O43181 436.6589 1.41E−01 5.03E−02 1 Unchanged Low Q9NWT5 445.8286 3.77E−01 5.61E−01 1 Unchanged Low O75431 395.1258 7.05E−01 6.48E−01 1 Unchanged Low P09543 409.9513 8.39E−01 9.80E−01 1 Unchanged Low Q9BTE1 494.9234 −2.83E−01 −2.91E−01 1 Unchanged Low P16152 312.5841 9.85E−01 3.30E−02 1 Unchanged Low O15121 333.1906 8.11E−01 3.08E−02 1 Unchanged Low O60909 403.197 3.46E−01 4.98E−02 1 Unchanged Low O75223 411.9427 −8.46E−02 −8.39E−01 1 Unchanged Low Q9BQA1 382.8783 2.98E−01 −3.22E−01 1 Unchanged Low O43427 371.8858 5.29E−01 6.63E−03 1 Unchanged Low Q9BWG6 457.7257 5.98E−01 9.45E−01 1 Unchanged Low Q9Y6R2 386.6911 4.77E−01 6.13E−02 1 Unchanged Low Q9HBK7 442.4205 3.59E−01 4.11E−01 1 Unchanged Low P52758 371.3427 5.36E−01 −3.19E−02 1 Unchanged Low P47897 412.2837 2.40E−01 −1.36E−01 1 Unchanged Low Q9BWQ6 415.0843 7.12E−01 7.43E−01 1 Unchanged Low P35325 483.0992 2.80E−01 5.82E−01 1 Unchanged Low Q9HA68 471.3877 −2.29E−01 −5.38E−01 1 Unchanged Low P49366 472.2313 5.17E−02 6.79E−02 1 Unchanged Low Q9UKZ7 477.7496 −7.79E−02 −1.67E−01 1 Unchanged Low P01730 475.788 −1.09E−01 −2.57E−01 1 Unchanged Low P20674 454.7764 −9.34E−02 −4.63E−01 1 Unchanged Low Q12828 418.2868 5.48E−02 −5.69E−01 1 Unchanged Low Q9Y6A4 442.0882 4.18E−01 4.32E−01 1 Unchanged Low O60888 361.3342 6.88E−01 2.62E−02 1 Unchanged Low O75716 408.0382 4.02E−01 5.66E−02 1 Unchanged Low P30711 447.6268 5.56E−01 7.02E−01 1 Unchanged Low Q15008 488.0851 2.01E−02 9.00E−02 1 Unchanged Low P17174 373.5229 2.32E−01 −8.84E−01 1 Unchanged Low P13798 400.3314 4.08E−01 −5.51E−02 1 Unchanged Low Q9P2R8 488.4865 4.52E−02 1.23E−01 1 Unchanged Low Q9UNT1 366.9843 8.51E−01 3.68E−01 1 Unchanged Low O75607 369.1972 4.71E−01 −3.66E−01 1 Unchanged Low O94925 456.0458 2.46E−01 1.98E−01 1 Unchanged Low O95390 359.3416 8.87E−01 2.92E−01 1 Unchanged Low O75956 498.9664 −1.01E−01 −1.22E−01 1 Unchanged Low O95573 339.2885 4.67E−01 −1.02E+00 1 Unchanged Low Q9BXH1 472.8963 −3.75E−03 −1.88E−01 1 Unchanged Low P13662 454.7336 3.27E−01 2.87E−01 1 Unchanged Low Q92793 478.8243 7.73E−02 1.53E−02 1 Unchanged Low Q9P0H6 456.7944 2.85E−01 2.06E−01 1 Unchanged Low Q9P0R3 447.9021 5.47E−01 5.87E−01 1 Unchanged Low O75094 426.952 5.21E−01 3.42E−01 1 Unchanged Low Q9P011 498.5084 1.11E−01 2.24E−01 1 Unchanged Low Q92504 362.6669 9.83E−01 4.28E−01 1 Unchanged Low O95190 453.1247 2.41E−01 6.55E−02 1 Unchanged Low Q9Y230 379.9805 5.41E−01 −1.89E−01 1 Unchanged Low Q9BSG0 426.9191 6.17E−01 4.98E−01 1 Unchanged Low Q9Y366 409.8539 8.41E−01 7.04E−01 1 Unchanged Low Q14094 420.31 2.94E−01 −2.05E−01 1 Unchanged Low P43403 430.7684 3.38E−01 −1.60E−03 1 Unchanged Low P52803 391.4643 4.87E−01 −1.79E−01 1 Unchanged Low O95402 222.265 2.24E+00 −8.52E−01 1 Unchanged Low O00233 494.287 −2.12E−01 −5.45E−01 1 Unchanged Low Q9H1K6 498.6205 2.16E−01 3.73E−01 1 Unchanged Low Q9BXL6 483.629 2.42E−01 2.99E−01 1 Unchanged Low Q9H173 469.6418 1.41E−01 −2.46E−02 1 Unchanged Low Q9NV83 475.4325 2.52E−01 2.30E−01 1 Unchanged Low P11926 486.3355 −2.27E−01 −7.07E−01 1 Unchanged Low Q04743 449.3322 −7.14E−02 −7.73E−01 1 Unchanged Low Q9BVK2 425.9595 3.80E−01 −2.18E−02 1 Unchanged Low O43251 461.1452 5.49E−01 6.12E−01 1 Unchanged Low Q99829 377.1688 5.17E−01 −4.09E−01 1 Unchanged Low O95777 403.8183 3.77E−01 −3.36E−01 1 Unchanged Low Q9UN53 414.6963 6.36E−01 3.13E−01 1 Unchanged Low P24310 327.1972 1.47E+00 6.46E−01 1 Unchanged Low Q9H929 465.7217 3.97E−01 3.67E−01 1 Unchanged Low P10768 402.8142 −2.24E−01 −2.55E+00 1 Unchanged Low O95287 472.3714 5.61E−01 6.95E−01 1 Unchanged Low Q01105 414.2142 6.37E−01 2.94E−01 1 Unchanged Low Q9UK45 483.7088 3.98E−01 5.04E−01 1 Unchanged Low P35611 488.7819 2.37E−01 2.54E−01 1 Unchanged Low O14681 430.8211 1.94E−01 −4.77E−01 1 Unchanged Low P80303 349.5918 8.03E−01 −3.28E−01 1 Unchanged Low Q9NWC0 476.3476 2.53E−01 1.34E−01 1 Unchanged Low P00367 394.0342 5.23E−01 −2.50E−01 1 Unchanged Low O00469 497.4006 −5.05E−01 −1.63+00 1 Unchanged Low Q9UI04 406.7523 5.15E−01 −1.17E−01 1 Unchanged Low P20338 488.5317 9.39E−02 −9.49E−02 1 Unchanged Low Q9HCU8 489.0161 2.51E−02 −2.53E−01 1 Unchanged Low P00519 352.0574 1.17E+00 3.73E−01 1 Unchanged Low Q13880 453.0588 −1.28E−01 −1.12E+00 1 Unchanged Low P25789 498.9408 2.70E−01 2.90E−01 1 Unchanged Low O43805 477.7167 5.17E−01 5.50E−01 1 Unchanged Low O75817 445.0255 4.89E−01 2.08E−01 1 Unchanged Low Q9UBI1 430.701 6.45E−01 3.45E−01 1 Unchanged Low P03950 374.4251 4.18E−01 −9.79E−01 1 Unchanged Low P78423 493.2272 1.39E+00 1.89E+00 1 Unchanged Low Q9P1D0 220.9467 3.20E+00 3.36E−01 1 Unchanged Low P03999 229.0786 2.19E+00 −1.62E+00 1 Unchanged Low O95793 483.6536 3.56E−01 2.54E−01 1 Unchanged Low P22750 393.9782 8.57E−01 2.19E−01 1 Unchanged Low 481.1517 3.27E−01 1.29E−01 1 Unchanged Low Q9NRX8 411.9671 1.69E+00 1.63E+00 1 Unchanged Low Q9UHQ3 410.1503 2.17E−01 −1.13E+00 1 Unchanged Low Q96S52 412.8095 4.34E−01 −4.99E−01 1 Unchanged Low Q9H3F6 462.5636 3.10E−01 −1.63E−01 1 Unchanged Low P37198 492.7531 3.63E−01 2.21E−01 1 Unchanged Low Q9H1D4 486.2744 3.59E−01 1.47E−01 1 Unchanged Low O75350 489.9278 2.02E−01 −1.40E−01 1 Unchanged Low Q9P024 467.714 5.83E−01 3.78E−01 1 Unchanged Low Q9Y224 492.0453 3.05E−01 7.30E−02 1 Unchanged Low Q13361 368.553 1.52E+00 8.67E−01 1 Unchanged Low Q02535 272.6788 2.73E+00 1.05E+00 1 Unchanged Low O95864 323.8122 9.07E−01 −1.40E+00 1 Unchanged Low P53621 480.1571 4.54E−01 2.01E−01 1 Unchanged Low P35638 401.9484 8.09E−01 −2.12E−02 1 Unchanged Low P22307 426.421 6.84E−01 5.58E−03 1 Unchanged Low Q92543 417.8592 7.95E−01 1.15E−01 1 Unchanged Low P78330 347.8406 1.17E+00 −2.03E−01 1 Unchanged Low Q9UNX3 472.8205 5.12E−01 1.48E−01 1 Unchanged Low P49189 434.2707 3.76E−01 −6.87E−01 1 Unchanged Low Q9ULX0 489.9828 2.47E−01 −2.81E−01 1 Unchanged Low O15353 495.2368 5.09E−01 2.85E−01 1 Unchanged Low Q9NRP2 461.731 6.03E−01 1.36E−01 1 Unchanged Low Q16280 469.6748 3.34E−01 −3.66E−01 1 Unchanged Low P04183 407.8979 7.63E−01 −2.64E−01 1 Unchanged Low Q12824 454.3734 1.43E+00 1.34E+00 1 Unchanged Low Q99719 474.0479 4.97E−01 −3.19E−02 1 Unchanged Low P46100 356.9983 9.40E−01 −8.93E−01 1 Unchanged Low Q16610 389.6774 1.32E+00 4.89E−01 1 Unchanged Low P39656 466.4028 4.64E−01 −2.39E−01 1 Unchanged Low P53814 461.5158 2.09E−01 −9.44E−01 1 Unchanged Low Q9P0N4 499.258 −1.90E+02 −1.09E−00 1 Unchanged Low Q9BXZ1 477.1895 3.76E−01 −3.62E−01 1 Unchanged Low Q9Y2Q4 444.641 8.42E−01 2.14E−01 1 Unchanged Low O15527 406.0683 8.73E−01 −2.27E−1 1 Unchanged Low Q04323 454.2076 2.95E−01 −9.61E−01 1 Unchanged Low P12004 416.0883 8.84E−01 −1.31E−01 1 Unchanged Low Q99720 452.6168 7.57E−01 5.85E−02 1 Unchanged Low P43307 389.0352 1.45E+00 5.10E−01 1 Unchanged Low Q9H3Y8 362.4108 1.49E+00 1.55E−01 1 Unchanged Low Q9NRX2 405.9846 1.14E+00 1.01E−01 1 Unchanged Low Q9P2X0 451.8107 1.16E+00 5.95E−01 1 Unchanged Low Q9Y5Z8 465.0297 8.23E−01 1.22E−01 1 Unchanged Low P78524 425.1425 9.06E−01 −2.50E−01 1 Unchanged Low P55145 496.4892 6.68E−01 2.26E−01 1 Unchanged Low P33551 440.861 1.18E+00 2.59E−01 1 Unchanged Low Q9BVQ0 259.6855 3.98E+00 3.32E−01 1 Unchanged Low P34897 472.1838 6.37E−01 −6.05E−01 1 Unchanged Low Q9Y5B4 491.1814 1.35E+00 9.52E−01 1 Unchanged Low Q9Y2V5 429.636 1.52E+00 3.94E−01 1 Unchanged Low Q13953 499.9658 1.09E+00 3.21E−01 1 Unchanged Low Q92686 455.4495 1.15E+00 −1.45E−01 1 Unchanged Low O60565 346.3594 2.87E+00 5.05E−01 1 Unchanged Low Q9Y4M4 481.2315 1.29E+00 −4.63E−01 1 Unchanged Low P16581 454.0605 3.00E+00 1.79E+01 1 Unchanged Low O14733 375.5944 3.17E+00 5.02E−01 1 Unchanged Low Q16623 498.3425 1.20E+00 −1.29E+00 1 Unchanged Low Q9P1M5 450.1426 5.05E+00 −1.01E+00 2 Unchanged Low O60613 1205.045 7.39E−02 −1.38E−01 2 Unchanged Medium Q16698 597.2594 3.89E−01 5.88E−01 2 Unchanged Medium Q9HBA8 557.2677 −2.95E−01 −1.47E+00 2 Unchanged Medium Q9P0I2 617.4113 1.70E−01 3.39E−01 2 Unchanged Medium Q9UL53 560.6322 −5.91E−01 −1.03E−01 2 Unchanged Medium P49902 900.9404 −1.24E+00 2.32E−01 2 Unchanged Medium O95336 697.4428 6.32E−01 5.27E−01 2 Unchanged Medium Q03393 525.0184 5.31E−01 9.66E−01 2 Unchanged Medium Q13443 744.5037 −1.55E+00 −1.44E+00 2 Unchanged Medium O75173 1033.446 6.74E−01 4.29E−01 2 Unchanged Medium P51572 843.6943 −5.85E−01 −1.48E−01 2 Unchanged Medium P42765 1111.329 5.03E−01 5.92E−01 2 Unchanged Medium P24666 1833.204 2.03E−01 2.59E−01 2 Unchanged Medium Q92688 531.9498 8.28E−01 −7.04E−01 2 Unchanged Medium O14639 701.2899 −1.91E+00 −1.78E+00 2 Unchanged Medium O15143 519.3549 −9.96E−01 −4.40E−01 2 Unchanged Medium O15509 868.6913 −1.71E−01 −3.18E−02 2 Unchanged Medium O15511 605.8842 −6.51E−01 −2.42E−01 2 Unchanged Medium P12718 1175.856 1.84E+00 5.32E−01 2 Unchanged Medium Q9P0I6 1014.448 4.11E−01 −1.79E−01 2 Unchanged Medium O43747 685.2957 −1.40E+00 −1.05E+00 2 Unchanged Medium P20172 1617.354 8.28E−01 −7.63E−03 2 Unchanged Medium O14617 510.4994 −9.28E−01 −4.57E−01 2 Unchanged Medium P07741 1190.468 −1.19E+01 −1.13E+00 2 Unchanged Medium P00568 1052.361 −2.76E+00 −2.59E+00 2 Unchanged Medium Q9U1J7 828.3999 −1.95E−01 4.87E−01 2 Unchanged Medium P30566 545.4304 6.41E−01 3.27E−01 2 Unchanged Medium Q16186 602.2578 −1.15E−01 −2.95E−02 2 Unchanged Medium Q9NVF6 582.9297 5.90E−01 4.72E−01 2 Unchanged Medium P26438 809.1342 2.60E−01 1.61E−01 2 Unchanged Medium P40616 1064.016 4.65E−01 5.64E−01 2 Unchanged Medium P36404 1723.74 9.61E−02 −1.77E−01 2 Unchanged Medium P56559 550.5764 2.28E−01 3.00E−01 2 Unchanged Medium P35368 1426.069 −1.02E−01 7.34E−02 2 Unchanged Medium P15144 563.2289 −1.04E+00 −2.15E+00 2 Unchanged Medium P30038 811.7082 −8.44E−01 −9.81E−01 2 Unchanged Medium P14550 683.9189 1.35E−01 6.74E−01 2 Unchanged Medium O43488 606.6855 4.54E−01 −5.74E−02 2 Unchanged Medium P09972 960.156 1.09E−01 2.63E−01 2 Unchanged Medium O43590 783.883 −6.13E−01 4.68E−01 2 Unchanged Medium Q08117 1476.318 −5.45E−01 −3.16E−01 2 Unchanged Medium Q13438 699.6136 2.86E−01 −4.36E−02 2 Unchanged Medium O96018 876.6611 5.52E−01 −2.38E−02 2 Unchanged Medium Q13564 679.5497 4.21E−01 1.78E−01 2 Unchanged Medium Q9Y679 1160.442 −2.21E−01 8.81E−02 2 Unchanged Medium Q9UKB4 622.7291 1.19E−01 5.66E−01 2 Unchanged Medium Q13725 1304.886 −4.98E−01 −1.36E−01 2 Unchanged Medium P08133 515.5041 1.80E+00 7.08E−01 2 Unchanged Medium P20073 517.0979 −6.29E−01 −4.36E−01 2 Unchanged Medium P03971 909.9247 −8.32E−01 −2.67E−01 2 Unchanged Medium P30041 1824.225 1.30E+00 −1.12E−01 2 Unchanged Medium P27695 718.2149 3.27E−01 −2.85E−02 2 Unchanged Medium Q9Y4J7 688.7802 −3.65E+00 −4.76E+00 2 Unchanged Medium Q9Y5L7 890.7729 1.11E+00 −1.86E−01 2 Unchanged Medium O94778 1455.01 −7.13E−04 −5.92E−02 2 Unchanged Medium O15296 718.1334 −1.99E−01 −4.45E−01 2 Unchanged Medium P48444 1288.649 8.92E−02 −1.07E−01 2 Unchanged Medium P00966 1199.548 −1.45E−01 6.08E−01 2 Unchanged Medium P42024 1518.804 7.54E−01 7.10E−01 2 Unchanged Medium O43681 620.0089 1.40E−01 4.23E−01 2 Unchanged Medium Q9ULX3 611.0757 −5.17E−01 −2.92E−01 2 Unchanged Medium O96030 749.363 −4.66E−01 −2.76E−01 2 Unchanged Medium P15289 1294.172 −6.96E−01 −4.14E−01 2 Unchanged Medium P08243 1024.719 7.89E−01 −4.72E−01 2 Unchanged Medium O95630 753.7548 1.43E−01 4.01E−01 2 Unchanged Medium O95135 530.0852 −1.40E+00 −1.39E+00 2 Unchanged Medium O14530 993.482 −1.11E−01 7.45E−01 2 Unchanged Medium P30049 511.6658 −5.02E−01 −4.16E−01 2 Unchanged Medium Q9UII2 878.5341 −2.76E−01 6.49E−01 2 Unchanged Medium Q9Y5K8 1232.91 4.53E−02 7.43E−01 2 Unchanged Medium O75787 947.5842 4.07E−01 2.13E−01 2 Unchanged Medium P05023 841.8422 −8.74E−01 −1.33E+00 2 Unchanged Medium P45844 616.8957 −5.11E−01 −1.18E+00 2 Unchanged Medium Q9HAP7 1730.54 3.68E−01 2.07E−01 2 Unchanged Medium O94812 961.2437 −3.77E−01 −1.27E−01 2 Unchanged Medium P35613 647.414 5.20E−01 −3.50E−01 2 Unchanged Medium Q9BSR6 1015.173 1.64E−01 6.88E−01 2 Unchanged Medium O00512 504.741 −4.08E+00 −4.15E+00 2 Unchanged Medium Q12983 767.5569 3.77E−01 −4.80E−01 2 Unchanged Medium Q92934 623.2249 1.64E−01 4.33E−01 2 Unchanged Medium Q07817 1890.905 −9.10E−01 2.85E−01 2 Unchanged Medium O43892 539.1375 −2.55E−01 −6.63E−01 2 Unchanged Medium P53004 523.696 6.39E−02 2.15E−01 2 Unchanged Medium O60629 956.1289 8.33E−01 9.53E−01 2 Unchanged Medium Q9HBX3 590.2997 −5.25E+00 −4.95E+00 2 Unchanged Medium P56945 1312.13 −3.34E−02 −4.14E−02 2 Unchanged Medium O15255 837.48 7.12E−01 −3.48E−01 2 Unchanged Medium P12830 835.8959 −1.16E+00 −2.45E−01 2 Unchanged Medium P19022 541.7151 1.15E+00 6.79E−01 2 Unchanged Medium P22223 823.6929 −1.27E+00 4.22E−01 2 Unchanged Medium P22676 1797.589 2.49E−01 −2.52E−01 2 Unchanged Medium Q99828 1096.979 −4.31E−01 2.26E−01 2 Unchanged Medium P02593 949.1389 −1.30E−01 −4.51E−01 2 Unchanged Medium Q13942 746.0174 −5.13E−02 −9.59E−01 2 Unchanged Medium P27824 1470.4 4.85E−02 −1.19E−01 2 Unchanged Medium P17655 685.847 −2.90E−01 3.17E−01 2 Unchanged Medium P04632 1490.643 −3.16E−01 7.36E−02 2 Unchanged Medium Q15417 750.6841 −3.06E−01 −5.95E−01 2 Unchanged Medium Q9UEG5 518.1163 −5.17E−01 −3.73E−01 2 Unchanged Medium P52907 705.5063 −5.36E−01 −3.11E−01 2 Unchanged Medium Q9GZX3 824.5253 −7.81E−02 2.28E−01 2 Unchanged Medium Q16619 1420.784 7.72E−02 −2.72E−01 2 Unchanged Medium Q9UBD9 581.3157 4.38E−01 1.30E+00 2 Unchanged Medium Q15699 817.569 5.71E−01 −3.26E−01 2 Unchanged Medium P48729 914.9218 3.86E−01 7.36E−01 2 Unchanged Medium P48730 1073.796 2.24E−01 2.84E−01 2 Unchanged Medium P19138 513.9702 −6.66E−02 3.03E−01 2 Unchanged Medium P49662 1831.485 −9.85E−01 2.90E−01 2 Unchanged Medium P21964 1046.831 8.63E−01 7.51E−01 2 Unchanged Medium P26232 774.9896 2.22E−02 −1.54E−01 2 Unchanged Medium P35222 1121.277 1.87E−01 4.14E−01 2 Unchanged Medium P07339 1111.314 −1.44E−01 −4.04E−01 2 Unchanged Medium Q99967 1711.366 7.95E−01 3.02E−01 2 Unchanged Medium P49715 937.3612 2.44E−01 1.26E−03 2 Unchanged Medium P53567 1191.643 9.38E−01 4.92E−01 2 Unchanged Medium O95627 716.7046 1.91E−01 4.89E−01 2 Unchanged Medium Q04900 664.5986 −1.55E−01 −3.97E−01 2 Unchanged Medium P07766 1953.844 5.48E−01 −3.59E−01 2 Unchanged Medium P34810 1617.586 −9.27E−01 −1.16E+00 2 Unchanged Medium P18582 1279.761 2.95E−01 −4.75E−01 2 Unchanged Medium Q16181 540.3444 8.16E−01 5.42E−02 2 Unchanged Medium Q16543 1158.574 2.99E−01 −4.35E−02 2 Unchanged Medium O14735 579.4931 3.67E−01 2.29E+00 2 Unchanged Medium P30260 1334.733 4.70E−01 4.74E−01 2 Unchanged Medium P49427 942.0784 7.74E−03 7.66E−01 2 Unchanged Medium P29373 1126.373 1.39E−01 −6.11E−01 2 Unchanged Medium P41208 629.3345 3.28E−01 3.18E−01 2 Unchanged Medium O00522 741.4854 −2.67E−01 −4.64E−01 2 Unchanged Medium O15183 632.0808 1.13E+00 5.98E−01 2 Unchanged Medium Q9Y2Z5 857.6492 7.06E−01 −9.94E−02 2 Unchanged Medium Q9Y3C3 1572.302 7.89E−01 1.49E−01 2 Unchanged Medium Q9Y3D0 1992.502 3.37E−01 5.75E−01 2 Unchanged Medium Q9Y3E5 629.3057 9.09E−02 5.66E−01 2 Unchanged Medium Q9Y3E8 829.1206 −1.33E−02 2.35E−01 2 Unchanged Medium Q9Y320 793.4541 −8.22E−02 3.22E−01 2 Unchanged Medium Q9Y357 668.441 −9.66E−01 −8.87E−02 2 Unchanged Medium Q9Y360 832.2061 1.93E−02 2.17E−01 2 Unchanged Medium Q9Y512 957.4201 1.12E−01 −1.71E−01 2 Unchanged Medium Q9Y390 1111.152 −2.88E−01 −7.96E−01 2 Unchanged Medium P40227 679.9043 −7.72E−01 −1.22E+00 2 Unchanged Medium Q99832 1274.983 3.79E−01 −1.33E−01 2 Unchanged Medium Q9UBR5 1303.992 1.62E−02 7.85E−01 2 Unchanged Medium Q9UHN8 1611.343 −3.42E−01 3.70E−01 2 Unchanged Medium P54105 532.9217 4.44E−01 4.80E−02 2 Unchanged Medium Q14781 753.0305 −1.57E−01 −8.68E−02 2 Unchanged Medium Q9BXS4 1050.603 4.91E−02 6.52E−01 2 Unchanged Medium Q9NPA0 897.3389 −2.18E−01 −2.60E−01 2 Unchanged Medium Q9UKR5 1207.747 1.21E−01 −3.18E−02 2 Unchanged Medium P56378 694.9486 8.23E−01 4.55E−01 2 Unchanged Medium O95433 552.8428 −5.80E−01 −2.20E−01 2 Unchanged Medium Q9NV31 848.9729 1.24E−02 −3.76E−02 2 Unchanged Medium Q9NVE2 596.0999 −4.69E−01 4.96E−02 2 Unchanged Medium Q9UI05 1952.881 −1.07E+00 −2.36E−01 2 Unchanged Medium Q9P0A7 954.524 1.04E+00 8.93E−01 2 Unchanged Medium Q9Y3B1 1235.108 −1.11E+00 −4.60E−01 2 Unchanged Medium Q9BQ89 1211.641 −2.58E−01 −6.17E−01 2 Unchanged Medium Q96C58 940.0036 −1.38E+00 −2.10E−01 2 Unchanged Medium Q9Y5Z4 758.6366 −1.30E+00 1.10E−01 2 Unchanged Medium Q00610 1427.503 −1.90E−01 −4.44E−01 2 Unchanged Medium P56749 1992.755 −8.75E−01 1.34E−01 2 Unchanged Medium O43809 608.9825 9.40E−02 −3.47E−01 2 Unchanged Medium O96005 1304.597 4.36E−02 −2.15E−01 2 Unchanged Medium Q16740 543.0367 −3.98E−01 −2.45E−01 2 Unchanged Medium P55085 734 −1.08E+00 2.39E−01 2 Unchanged Medium P13726 800.9723 −1.29E+00 −2.94E−01 2 Unchanged Medium Q9Y678 854.5161 3.08E−01 −1.45E−01 2 Unchanged Medium Q15363 793.6589 3.01E−01 1.88E−01 2 Unchanged Medium O43513 623.9284 4.33E−01 −2.99E−01 2 Unchanged Medium Q9Y281 678.6369 7.03E−01 −1.31E+00 2 Unchanged Medium P04141 522.783 5.12E−01 3.47E+00 2 Unchanged Medium P02745 1042.465 2.24E−01 1.27E+00 2 Unchanged Medium P29279 734.8489 8.45E−01 −1.52E−01 2 Unchanged Medium O43191 1062.925 6.06E−01 2.68E−01 2 Unchanged Medium Q99627 984.0634 6.01E−01 2.97E−01 2 Unchanged Medium O15387 533.8251 8.88E−02 −6.30E−01 2 Unchanged Medium Q9ULV4 1385.839 −2.26E−01 −4.09E−01 2 Unchanged Medium Q9BR76 827.7864 −3.65E−02 6.13E−01 2 Unchanged Medium Q14061 1026.374 −2.54E−01 7.00E−01 2 Unchanged Medium Q9Y6B2 1323.308 1.07E+00 1.27E−01 2 Unchanged Medium Q9NY68 991.4995 −8.09E−01 −7.81E−01 2 Unchanged Medium P24385 1486.769 −1.42E−01 8.21E−01 2 Unchanged Medium Q9NXT4 1620.99 2.03E−02 1.40E−01 2 Unchanged Medium P01034 1134.612 3.57E−01 −1.37E−01 2 Unchanged Medium Q15828 1404.267 −1.10E+00 1.53E+00 2 Unchanged Medium P01036 932.4892 −2.38E−01 −1.44E+00 2 Unchanged Medium P52943 883.82 5.48E−01 −8.08E−01 2 Unchanged Medium P13498 707.7483 −9.81E−01 5.73E−01 2 Unchanged Medium P00167 1565.893 −1.08E+00 −5.67E−01 2 Unchanged Medium P00001 502.4786 −8.14E−02 −3.09E−01 2 Unchanged Medium P10606 1851.225 6.14E−01 6.24E−01 2 Unchanged Medium P08574 517.4383 −5.97E−01 −5.93E−01 2 Unchanged Medium Q99426 673.9633 4.71E−01 2.85E−01 2 Unchanged Medium Q07065 987.5887 1.57E+00 −6.78E−02 2 Unchanged Medium Q15038 754.4305 −5.17E−01 1.40E−01 2 Unchanged Medium Q9H2L4 630.0414 9.35E−01 7.82E−01 2 Unchanged Medium Q9NPA8 1342.189 6.81E−01 7.32E−01 2 Unchanged Medium O60231 808.7915 8.50E−02 2.11E−01 2 Unchanged Medium Q9GZR7 854.0965 −5.31E−02 2.93E−01 2 Unchanged Medium P17844 1530.749 1.72E−01 −4.26E−02 2 Unchanged Medium Q08211 824.2193 −2.41E−04 −4.65E−01 2 Unchanged Medium Q9UJV9 1024.437 −1.66E−01 3.28E−01 2 Unchanged Medium P51398 905.1904 −1.76E−01 9.20E−02 2 Unchanged Medium Q13437 1596.672 1.37E−01 −5.88E−02 2 Unchanged Medium O60735 609.2393 −8.78E−01 −7.75E−01 2 Unchanged Medium Q16854 910.8082 2.05E−01 4.43E−02 2 Unchanged Medium Q9Y295 676.9267 −1.56E−01 −2.17E−01 2 Unchanged Medium P00387 1290.593 3.42E−02 −4.40E−01 2 Unchanged Medium Q9UHY9 741.1 7.87E−01 4.44E−01 2 Unchanged Medium P36957 577.6196 −6.69E−01 1.88E−01 2 Unchanged Medium Q99075 518.9525 −1.87E+00 −1.78E−01 2 Unchanged Medium Q9UFN1 1127.658 6.04E−01 −2.91E−02 2 Unchanged Medium O95882 870.3185 −2.26E−01 −1.22E−01 2 Unchanged Medium Q9Y269 998.4411 8.38E−01 7.17E−01 2 Unchanged Medium Q9NWE3 605.084 5.77E−01 8.76E−01 2 Unchanged Medium Q9H6Y7 1352.292 −2.23E−01 8.55E−02 2 Unchanged Medium Q9Y3X0 588.5767 1.93E−01 −2.21E−01 2 Unchanged Medium O60762 531.3373 5.74E−01 5.14E−01 2 Unchanged Medium P53805 515.0794 4.68E−01 8.42E−01 2 Unchanged Medium Q13597 636.966 6.87E−02 2.20E−01 2 Unchanged Medium Q9C005 1064.132 5.35E−01 5.76E−01 2 Unchanged Medium Q13448 1586.247 9.42E−01 −1.27E−01 2 Unchanged Medium Q9UHF9 703.5318 −1.86E+00 −8.23E−01 2 Unchanged Medium P51452 576.1845 −4.56E−01 −1.02E−01 2 Unchanged Medium Q14203 553.5576 2.97E−01 6.06E−02 2 Unchanged Medium Q13561 1372.261 −4.16E−01 −1.84E−01 2 Unchanged Medium Q13409 620.6506 −7.71E−01 −3.94E−01 2 Unchanged Medium Q09472 1651.644 −1.56E−01 5.00E−01 2 Unchanged Medium 588.0816 −4.51E−01 2.28E−02 2 Unchanged Medium P78365 907.5945 −2.32E−01 2.54E−01 2 Unchanged Medium Q99848 802.3778 −2.56E−01 −6.79E−01 2 Unchanged Medium Q12805 597.7763 −1.13E+00 −1.60E+00 2 Unchanged Medium Q9Y6I3 621.9752 −2.28E−01 −5.60E−01 2 Unchanged Medium Q15717 831.3485 −1.26E−02 −8.94E−02 2 Unchanged Medium P13804 664.3533 −7.96E−01 −7.54E−01 2 Unchanged Medium Q14247 1063.9 −1.80E−01 −1.06E−01 2 Unchanged Medium P42892 737.1982 4.27E−01 4.08E−01 2 Unchanged Medium P30084 917.9548 −1.14E−01 5.93E−01 2 Unchanged Medium P07099 1424.661 −3.96E−02 5.83E−01 2 Unchanged Medium P29692 1061.631 −2.59E−01 −8.37E−01 2 Unchanged Medium P20042 1016.24 −6.39E−01 −1.30E+00 2 Unchanged Medium P41091 565.2535 −6.33E−01 −6.46E−01 2 Unchanged Medium Q99613 997.2011 −1.91E−01 −4.19E−01 2 Unchanged Medium P78344 1419.665 −4.08E−01 −4.19E−02 2 Unchanged Medium P23588 1160.659 −2.54E−01 −4.07E−01 2 Unchanged Medium Q13541 1669.873 4.70E−01 −6.43E−01 2 Unchanged Medium Q13542 1712.605 3.79E−02 1.95E−01 2 Unchanged Medium O60573 833.9147 3.49E−02 1.42E−01 2 Unchanged Medium Q16394 584.9471 6.63E−01 −2.64E−01 2 Unchanged Medium P37268 610.2023 −1.62E−01 −6.73E−01 2 Unchanged Medium P55899 566.0193 7.86E−02 7.74E−01 2 Unchanged Medium Q9UK73 541.9489 −4.67E−02 −3.93E−03 2 Unchanged Medium P21333 966.2982 4.33E−01 −4.86E−01 2 Unchanged Medium P26885 662.0387 −3.01E−01 −6.76E−01 2 Unchanged Medium Q13451 1097.248 −7.50E−01 −2.98E−01 2 Unchanged Medium O95633 1227.557 −2.64E−01 −3.86E−02 2 Unchanged Medium P15407 1421.01 −4.77E−01 −3.31E−01 2 Unchanged Medium Q14192 703.7424 1.97E+00 9.30E−01 2 Unchanged Medium Q9NZA0 981.791 2.65E−01 −2.13E−02 2 Unchanged Medium P35637 893.3381 4.21E−01 −4.06E−01 2 Unchanged Medium 935.6666 −2.32E−01 1.71E−01 2 Unchanged Medium Q9Y653 1889.081 −4.21E−01 1.00E−01 2 Unchanged Medium Q9H1C0 727.2869 1.55E−02 7.47E−02 2 Unchanged Medium P15170 1521.226 −8.80E−01 −5.33E−01 2 Unchanged Medium O95166 1572.36 −6.11E−02 7.87E−01 2 Unchanged Medium O08765 1095.839 −4.34E−01 −1.39E−01 2 Unchanged Medium P16278 665.3025 2.82E−01 5.69E−01 2 Unchanged Medium P78537 790.0409 1.77E−01 −3.52E−01 2 Unchanged Medium P31150 722.7008 1.47E−02 4.97E−01 2 Unchanged Medium P06396 513.4286 9.40E−01 8.05E−01 2 Unchanged Medium P52657 641.1721 3.78E−01 3.46E−01 2 Unchanged Medium Q00403 582.2035 −1.38E−01 6.61E−01 2 Unchanged Medium P48060 707.2232 1.54E−01 3.35E−02 2 Unchanged Medium P06744 726.7688 −3.11E−01 −7.05E−01 2 Unchanged Medium P30101 1726.668 3.78E−01 −4.50E−01 2 Unchanged Medium O43836 1758.853 −6.36E−02 1.29E−01 2 Unchanged Medium P15104 1130.151 1.17E−02 −1.71E−01 2 Unchanged Medium Q06210 777.6585 −1.06E−02 −5.34E−01 2 Unchanged Medium Q9Y3D4 960.4756 3.07E−01 8.32E−03 2 Unchanged Medium Q9Y2Q3 533.8957 −1.02E+00 −1.28E+00 2 Unchanged Medium P48637 522.9685 −4.13E−01 −6.00E−01 2 Unchanged Medium P78417 1937.888 −1.36E−01 2.95E−02 2 Unchanged Medium P49840 1254.087 2.39E−01 4.63E−01 2 Unchanged Medium P13224 557.0977 4.23E−01 1.22E−01 2 Unchanged Medium Q9UBQ7 973.9926 7.50E−02 4.55E−02 2 Unchanged Medium Q9P2T1 882.4154 1.01E−01 4.87E−01 2 Unchanged Medium Q9H4A6 1148.94 2.35E−01 2.35E−01 2 Unchanged Medium P28799 1532.188 −3.79E−01 1.16E−01 2 Unchanged Medium Q14393 595.5619 6.09E−01 2.17E−01 2 Unchanged Medium P29354 746.3732 −1.22E−01 2.44E−01 2 Unchanged Medium Q14451 731.6029 −1.61E−01 2.47E−01 2 Unchanged Medium Q9Y6G2 1093.42 −4.04E−1 −3.43E−01 2 Unchanged Medium P04899 1334.01 1.02E+00 6.94E−01 2 Unchanged Medium P11016 789.4586 1.41E−01 2.73E−02 2 Unchanged Medium Q13905 504.61 3.84E−01 4.71E−01 2 Unchanged Medium Q16774 1095.967 1.08E−02 4.72E−01 2 Unchanged Medium Q9Y649 1971.464 1.41E−01 5.39E−01 2 Unchanged Medium P07305 1797.448 −2.77E−02 6.73E−02 2 Unchanged Medium O75367 786.0181 −1.23E+00 −3.48E−01 2 Unchanged Medium P17317 874.2269 1.41E+00 −3.58E−01 2 Unchanged Medium P02278 707.973 2.22E−01 5.38E−01 2 Unchanged Medium Q9NS37 725.1835 −5.11E−01 −2.59E−01 2 Unchanged Medium O96004 646.3401 −1.84E−01 −2.04E−01 2 Unchanged Medium P10809 1330.235 −4.08E−01 −7.30E−01 2 Unchanged Medium P34932 1352.283 −4.28E−01 2.01E−01 2 Unchanged Medium P07900 1783.374 −6.70E−01 −7.48E−01 2 Unchanged Medium P08238 1903.993 −1.51E+00 −5.11E−01 2 Unchanged Medium O75506 1171.256 −6.57E−02 1.99E−01 2 Unchanged Medium Q9UHG4 549.5035 4.80E−01 6.73E−01 2 Unchanged Medium P09105 651.9692 1.31E−01 −5.37E−01 2 Unchanged Medium O43504 1097.672 −8.79E−02 4.05E−01 2 Unchanged Medium Q9H2I6 590.1783 −5.14E−01 −1.27E−01 2 Unchanged Medium P51858 850.7213 −8.65E−01 3.85E−01 2 Unchanged Medium Q04150 959.787 1.76E−01 −1.16E−01 2 Unchanged Medium Q13151 998.1703 3.34E−01 5.77E−02 2 Unchanged Medium P22626 1206.298 6.33E−01 −1.38E−02 2 Unchanged Medium P07910 841.6601 5.03E−01 −5.79E−02 2 Unchanged Medium O14979 1563.717 6.38E−01 9.10E−01 2 Unchanged Medium P52597 1567.536 −3.27E−01 −5.69E−01 2 Unchanged Medium Q07244 733.1055 −3.09E−01 −3.46E−01 2 Unchanged Medium Q15584 717.4409 2.43E−01 −3.51E−01 2 Unchanged Medium P12081 514.8575 −3.89E−01 2.34E−02 2 Unchanged Medium Q9UBN7 595.8457 2.01E−02 −7.53E−01 2 Unchanged Medium Q13838 735.5784 4.36E−01 −1.75E−01 2 Unchanged Medium Q99873 978.6584 4.43E−01 −9.05E−02 2 Unchanged Medium Q9H063 893.139 4.45E−01 3.05E−01 2 Unchanged Medium P51610 632.9786 3.33E−01 −9.25E−03 2 Unchanged Medium O00165 1800.489 7.11E−01 1.12E−02 2 Unchanged Medium Q9Y2Q5 752.165 1.13E−02 7.02E−01 2 Unchanged Medium Q9Y2R0 1668.909 2.44E−01 1.87E−01 2 Unchanged Medium Q9Y2T0 504.1821 −4.73E−01 6.94E−01 2 Unchanged Medium Q9UNZ5 1159.538 7.07E−01 6.62E−01 2 Unchanged Medium Q9P032 668.1435 5.93E−01 1.08E−01 2 Unchanged Medium Q9P019 1312.254 1.08E+00 1.24E+00 2 Unchanged Medium Q9P004 932.7666 −1.11E+00 −1.43E−01 2 Unchanged Medium Q9P003 1118.827 5.19E−01 8.11E−01 2 Unchanged Medium Q9P000 650.7428 4.24E−02 8.57E−01 2 Unchanged Medium Q9Y684 665.044 4.85E−01 1.39E−01 2 Unchanged Medium Q9NRG2 1462.8 3.61E−01 2.07E−01 2 Unchanged Medium Q16775 531.4885 −3.29E−01 4.03E−01 2 Unchanged Medium P40939 1733.575 −1.66E−01 −3.69E−02 2 Unchanged Medium P55084 882.3271 1.18E+00 7.22E−01 2 Unchanged Medium Q14526 943.6552 1.35E−01 −2.30E−02 2 Unchanged Medium Q9UBS2 628.6277 −3.79E−01 2.40E−02 2 Unchanged Medium Q96EW8 518.5858 −1.70E+00 −2.67E−01 2 Unchanged Medium Q9Y2S6 1423.596 4.23E−01 3.26E−01 2 Unchanged Medium Q9UKZ1 592.3978 −3.77E−01 −9.84E−02 2 Unchanged Medium Q9UJJ9 576.3525 4.75E−01 6.85E−01 2 Unchanged Medium O95891 1741.841 −1.81E−01 3.07E−01 2 Unchanged Medium Q9UJI9 1019.924 −1.55E−01 −2.60E−01 2 Unchanged Medium Q9H0U3 1169.228 −1.68E−01 −2.59E−01 2 Unchanged Medium Q9NWD8 741.1753 −8.68E−02 5.11E−03 2 Unchanged Medium Q9NW90 548.3816 2.89E−01 1.61E−01 2 Unchanged Medium Q9NW61 745.7235 −3.14E−01 1.29E−01 2 Unchanged Medium Q9NW16 589.0741 −6.93E−01 −4.78E−01 2 Unchanged Medium Q9NVZ3 500.7932 −2.70E−01 6.81E−01 2 Unchanged Medium Q9NVC3 976.6359 −1.23E+00 −5.95E−01 2 Unchanged Medium Q9H9K7 565.6072 4.12E−01 5.59E−01 2 Unchanged Medium Q9H8H4 1084.852 4.26E−01 −4.50E−01 2 Unchanged Medium Q9P0R5 834.4521 6.70E−01 −3.78E−02 2 Unchanged Medium Q9NXQ4 1521.653 3.89E−02 1.13E−02 2 Unchanged Medium Q9NXI2 566.3149 −1.85E+00 4.47E−01 2 Unchanged Medium Q9NXD5 932.5386 2.97E−01 1.20E+00 2 Unchanged Medium Q9NX64 915.2399 6.42E−02 −1.86E−01 2 Unchanged Medium Q9NWX1 1565.249 1.66E−01 3.95E−01 2 Unchanged Medium Q9NWT8 934.2965 −1.12E−01 −9.99E−02 2 Unchanged Medium Q9NWM3 554.671 8.56E−01 6.37E−01 2 Unchanged Medium Q9H7C7 615.0164 8.53E−02 3.61E−01 2 Unchanged Medium Q9H6R6 500.0538 6.75E−01 −1.04E−01 2 Unchanged Medium Q9H673 1047.134 −1.39E+00 −1.98E−01 2 Unchanged Medium O95476 1279.962 1.81E−01 −3.27E−01 2 Unchanged Medium Q9Y244 1481.658 −4.23E−01 −1.22E−01 2 Unchanged Medium Q9P022 610.0993 −4.97E−02 −3.56E−01 2 Unchanged Medium Q9P013 1167.03 3.06E−01 6.63E−01 2 Unchanged Medium Q9P009 1008.218 −6.40E−01 3.67E−01 2 Unchanged Medium Q9P0S9 1622.151 5.51E−01 2.36E−01 2 Unchanged Medium Q9NPI0 532.0086 1.26E+00 1.20E+00 2 Unchanged Medium O95887 679.3596 −4.95E−01 −1.34E−01 2 Unchanged Medium Q9P0T9 1322.295 2.52E−01 7.04E−02 2 Unchanged Medium Q9P0Q1 774.623 1.43E+00 1.31E+00 2 Unchanged Medium Q9P0P0 1798.292 5.49E−01 7.50E−01 2 Unchanged Medium Q9P0N9 506.0883 1.61E−01 −5.32E−01 2 Unchanged Medium Q9NZD9 607.2015 −2.44E−01 2.52E−01 2 Unchanged Medium O75207 663.0017 3.63E−02 −4.30E−02 2 Unchanged Medium Q9BWL0 579.5932 3.63E−01 −3.87E−01 2 Unchanged Medium Q9BW61 1754.667 −9.46E−02 7.68E−01 2 Unchanged Medium Q9BQ49 628.1009 3.59E−01 3.63E−01 2 Unchanged Medium Q9BQD3 876.8925 9.67E−02 7.95E−02 2 Unchanged Medium Q9BQ61 1794.728 6.82E−01 8.13E−01 2 Unchanged Medium Q9BTV4 548.9637 5.52E−02 −1.63E−01 2 Unchanged Medium Q9BVX2 704.7101 −3.06E−01 2.91E−02 2 Unchanged Medium Q9H773 734.1306 −4.53E−01 3.57E−02 2 Unchanged Medium Q9BPX5 546.6359 1.16E−01 −4.60E−01 2 Unchanged Medium Q9UJX8 1083.179 −8.46E−02 −3.21E−01 2 Unchanged Medium P00492 669.9473 −1.10E+00 −2.38E+00 2 Unchanged Medium P22304 1205.085 −1.28E−01 1.43E−01 2 Unchanged Medium Q03827 574.4895 −2.79E−01 −2.78E−01 2 Unchanged Medium P12268 1038.44 4.39E−02 −1.15E+00 2 Unchanged Medium Q9Y6K9 805.9933 −2.60E−02 −6.18E−02 2 Unchanged Medium Q14573 609.9521 1.75E−01 2.17E−01 2 Unchanged Medium O15357 1146.828 3.71E−01 2.08E−01 2 Unchanged Medium O15503 505.2037 3.84E−01 −1.42E−01 2 Unchanged Medium P52945 1961.135 −9.45E−01 1.36E+00 2 Unchanged Medium P51460 1184.891 −2.38E−01 6.76E−02 2 Unchanged Medium P46977 1998.711 5.71E−01 7.81E−02 2 Unchanged Medium Q13418 1300.502 2.55E−01 −4.79E−01 2 Unchanged Medium P48551 554.33 −6.37E−01 1.44E−01 2 Unchanged Medium P15260 1648.504 1.64E−02 1.16E+00 2 Unchanged Medium P38484 638.9669 −1.10E−01 3.80E−01 2 Unchanged Medium O14896 617.9736 −2.85E−01 9.39E−01 2 Unchanged Medium 515.9592 −4.29E−01 −3.80E−01 2 Unchanged Medium Q14116 1230.533 −1.45E+00 7.71E−02 2 Unchanged Medium O75874 687.2716 4.53E−01 −4.14E−01 2 Unchanged Medium P51553 832.7908 −5.67E−02 1.40E−01 2 Unchanged Medium P41252 650.6946 6.24E−01 −1.03E+00 2 Unchanged Medium Q9UE89 604.7722 8.21E−01 −5.17E−01 2 Unchanged Medium P52292 1350.126 5.95E−01 2.04E−01 2 Unchanged Medium P24390 1392.342 −1.41E−01 −3.65E−01 2 Unchanged Medium P08779 754.7055 −2.99E−01 −5.39E−02 2 Unchanged Medium Q04695 937.9159 8.64E−01 1.02E+00 2 Unchanged Medium Q07666 1031.926 −1.37E−01 −6.37E−01 2 Unchanged Medium Q14165 669.3755 2.27E+00 2.89E−01 2 Unchanged Medium Q12765 979.0013 4.48E−02 7.68E−02 2 Unchanged Medium O43310 542.3144 2.06E−01 2.88E−01 2 Unchanged Medium O43167 1160.899 −3.43E−01 −5.10E−01 2 Unchanged Medium Q9H7D5 1291.483 2.60E−01 1.12E+00 2 Unchanged Medium Q9HD96 1044.592 −3.76E−01 −7.25E−01 2 Unchanged Medium O00182 864.4149 −5.28E−01 7.79E−01 2 Unchanged Medium Q99538 695.3901 1.25E+00 1.53E−01 2 Unchanged Medium O95751 706.7407 1.50E−01 −1.67E+00 2 Unchanged Medium O15468 962.0679 4.38E−01 1.84E−01 2 Unchanged Medium Q9UBB4 731.0054 −3.41E−01 −4.94E−01 2 Unchanged Medium Q9UFW4 1834.238 3.36E−01 1.79E−02 2 Unchanged Medium Q14847 772.769 4.30E−01 1.91E−01 2 Unchanged Medium O00158 703.0924 1.56E+00 −6.16E−01 2 Unchanged Medium Q9HAP6 1945.862 4.10E−02 −4.50E−01 2 Unchanged Medium P38571 568.1283 −2.36E−01 −4.02E−02 2 Unchanged Medium Q99732 674.31 −5.98E−01 3.92E−01 2 Unchanged Medium Q9Y4Z1 1511.517 −3.95E−02 −3.40E−01 2 Unchanged Medium O75896 688.0098 −2.00E−01 1.61E−01 2 Unchanged Medium Q06643 582.7217 −4.41E−01 1.36E+00 2 Unchanged Medium O95372 656.485 6.49E−01 6.18E−01 2 Unchanged Medium P13473 1408.92 4.24E−01 1.07E+00 2 Unchanged Medium Q08397 1753.531 6.89E−01 2.25E−01 2 Unchanged Medium Q15046 665.5485 −7.39E−01 −6.96E−01 2 Unchanged Medium Q13312 628.231 −4.92E−01 −6.85E−01 2 Unchanged Medium Q09160 1841.106 −2.40E−01 8.30E−01 2 Unchanged Medium P40925 1007.157 −7.12E−02 −5.38E−01 2 Unchanged Medium P40926 1251.158 −3.32E−01 −5.88E−01 2 Unchanged Medium Q16626 1536.52 5.44E−01 2.87E−01 2 Unchanged Medium Q9NQG1 689.9075 4.66E−01 5.85E−01 2 Unchanged Medium P26572 625.3732 5.18E−01 −7.49E−01 2 Unchanged Medium Q10469 606.4146 8.52E−02 −4.29E−02 2 Unchanged Medium P41223 503.5179 6.29E−01 5.96E−01 2 Unchanged Medium Q9Y5V3 1008.268 2.08E+00 1.26E+00 2 Unchanged Medium P43121 704.4837 −1.04E+00 −1.56E−01 2 Unchanged Medium Q92494 952.9144 −2.23E−01 1.11E−01 2 Unchanged Medium Q14444 560.0583 −2.41E−01 2.77E−01 2 Unchanged Medium Q9NPE2 922.5469 5.33E−01 3.14E−01 2 Unchanged Medium Q92571 533.4868 −2.01E−01 −4.71E−01 2 Unchanged Medium O95204 520.899 −6.19E−01 −1.08E+00 2 Unchanged Medium P80297 582.747 1.55E−01 −2.32E−01 2 Unchanged Medium Q99735 529.1741 −4.96E−01 3.79E−01 2 Unchanged Medium Q98XW5 609.0447 1.84E+00 1.49E−00 2 Unchanged Medium Q9Y6C9 1892.145 1.39E−02 2.56E−02 2 Unchanged Medium Q9Y3B7 517.9208 8.68E−01 6.88E−02 2 Unchanged Medium Q9P015 634.2498 8.94E−02 4.57E−01 2 Unchanged Medium Q9NX20 613.4293 1.25E−01 −3.74E−01 2 Unchanged Medium Q9H0U6 856.3674 1.57E−01 4.32E−01 2 Unchanged Medium Q9NZE8 927.2731 6.45E−02 −7.77E−03 2 Unchanged Medium Q9P0P3 1101.306 −2.51E−02 −4.50E−01 2 Unchanged Medium Q9Y317 1063.499 7.79E−01 3.49E−01 2 Unchanged Medium Q9Y6G3 690.2211 2.70E−01 5.02E−01 2 Unchanged Medium Q9BYC7 591.6118 3.36E−01 4.39E−01 2 Unchanged Medium Q9Y3D3 997.1495 5.88E−02 7.41E−02 2 Unchanged Medium Q9Y676 674.9976 1.57E−01 −2.37E−01 2 Unchanged Medium Q9Y3D5 865.8021 2.46E−01 6.27E−01 2 Unchanged Medium P82921 1019.33 5.76E−01 6.75E−01 2 Unchanged Medium P82650 513.1921 −2.36E−01 −1.07E−01 2 Unchanged Medium Q9Y2Q9 1395.534 −1.14E−01 −2.15E−02 2 Unchanged Medium Q9NP92 606.105 −1.16E−01 −3.31E−01 2 Unchanged Medium Q02750 590.1129 −4.40E−01 1.87E−01 2 Unchanged Medium Q02779 510.095 −2.29E−01 −4.96E−01 2 Unchanged Medium Q12851 994.1804 −1.67E−02 4.26E−02 2 Unchanged Medium P49137 1004.624 1.81E−01 8.87E−02 2 Unchanged Medium Q9BYG3 502.0002 −1.36E+00 −9.61E−01 2 Unchanged Medium Q15014 1144.777 1.39E−01 −1.61E−01 2 Unchanged Medium 999.5166 −2.17E−01 −1.60E−02 2 Unchanged Medium Q15773 603.749 4.09E−01 −3.06E−01 2 Unchanged Medium P35579 1261.007 −2.44E−01 −3.07E−01 2 Unchanged Medium Q9Y6D2 504.9319 −9.51E−01 4.14E−01 2 Unchanged Medium P41227 841.2057 3.13E−02 1.76E−01 2 Unchanged Medium Q13510 1028.456 −1.51E−01 1.14E+00 2 Unchanged Medium O43678 1810.699 6.45E−01 4.96E−01 2 Unchanged Medium O95167 1570.238 7.39E−02 3.08E−01 2 Unchanged Medium P56556 1120.973 −1.05E+00 −8.49E−01 2 Unchanged Medium O95182 750.6457 −4.87E−02 5.03E−02 2 Unchanged Medium P51970 767.6928 8.82E−01 3.93E−01 2 Unchanged Medium O96000 1219.156 1.84E−03 3.71E−01 2 Unchanged Medium O95178 836.3224 −1.83E−01 −2.68E−01 2 Unchanged Medium O95139 1678.472 6.34E−01 8.78E−02 2 Unchanged Medium P17568 648.3703 −4.13E−01 −4.74E−01 2 Unchanged Medium Q9Y6M9 1164.524 −7.99E−01 1.55E−01 2 Unchanged Medium O43677 573.2205 −1.39E−01 3.43E−02 2 Unchanged Medium O00217 1234.615 −2.12E−01 −2.96E−01 2 Unchanged Medium P19404 650.0945 −1.69E+00 −1.38E+00 2 Unchanged Medium O76008 698.4474 −7.64E−01 4.01E−01 2 Unchanged Medium Q9UPY4 505.6782 5.46E−01 1.40E−01 2 Unchanged Medium 1042.081 −2.79E−01 −5.27E−01 2 Unchanged Medium Q99742 695.8521 −8.28E−01 −1.41E+00 2 Unchanged Medium O60448 1662.051 −2.97E−01 −1.38E−01 2 Unchanged Medium Q9UNW9 1106.982 2.16E−01 1.70E−03 2 Unchanged Medium Q9UGL9 923.3423 −1.43E+00 4.08E−01 2 Unchanged Medium Q9UGL6 1086.502 6.53E−02 6.09E−01 2 Unchanged Medium Q92982 519.6952 −1.53E−01 5.88E−01 2 Unchanged Medium Q9BPW8 640.3075 −5.59E−01 −6.50E−01 2 Unchanged Medium Q9NQR4 684.4701 3.59E−01 7.42E−01 2 Unchanged Medium Q9UF10 1608.811 1.55E−01 5.83E−01 2 Unchanged Medium Q9Y385 701.1992 9.84E−02 3.69E−01 2 Unchanged Medium Q15233 1174.503 1.88E−01 1.55E−01 2 Unchanged Medium Q13137 923.1712 5.26E−02 5.31E−03 2 Unchanged Medium Q16236 1153.088 −2.41E−01 −6.20E−02 2 Unchanged Medium P08651 669.8575 −1.38E−01 −2.19E−01 2 Unchanged Medium O95134 508.0938 2.06E−01 1.67E−01 2 Unchanged Medium Q15772 1184.738 −3.49E−01 −6.75E−01 2 Unchanged Medium Q9UHY1 694.4539 2.64E−01 8.77E−01 2 Unchanged Medium Q9UPC9 982.77 1.81E−01 5.36E−01 2 Unchanged Medium Q15325 1808.771 3.28E−01 6.25E−02 2 Unchanged Medium O00567 630.2325 −8.14E−02 −1.17E−01 2 Unchanged Medium Q9NX24 561.9547 3.51E−01 4.22E−01 2 Unchanged Medium P06748 1275.358 −4.98E−01 −5.67E−01 2 Unchanged Medium P50583 684.354 −2.66E+00 −2.91E+00 2 Unchanged Medium Q9UHM6 1305.239 6.10E−01 1.50E−01 2 Unchanged Medium Q9Y218 1302.823 −1.54E−01 9.66E−01 2 Unchanged Medium Q16612 967.7934 2.79E+00 1.12E−01 2 Unchanged Medium P55771 548.4374 −2.73E−01 −8.67E−01 2 Unchanged Medium Q9UKJ1 560.9087 −2.72E−01 −5.83E−01 2 Unchanged Medium Q15165 604.4337 7.86E−01 1.40E+00 2 Unchanged Medium Q07002 795.1858 −4.03E−01 1.31E−01 2 Unchanged Medium Q9Y3C6 602.0621 −5.90E−02 4.14E−01 2 Unchanged Medium P30405 745.2396 −8.50E−01 1.33E−01 2 Unchanged Medium O43924 567.4949 9.06E−01 7.56E−01 2 Unchanged Medium P17858 750.1835 −2.95E−01 −8.56E−01 2 Unchanged Medium Q01813 591.6879 −4.50E−02 1.71E−01 2 Unchanged Medium O00511 1704.656 7.83E−01 1.70E−01 2 Unchanged Medium P11216 666.5476 9.35E−01 −6.30E−02 2 Unchanged Medium P00749 1861.568 −5.98E−02 1.65E+00 2 Unchanged Medium P13797 1062.438 4.93E−01 −3.00E−01 2 Unchanged Medium Q15102 537.6672 −3.08E−03 5.20E−01 2 Unchanged Medium P01127 543.5869 −1.33E−01 4.28E−01 2 Unchanged Medium Q15795 612.22 −1.57E−01 3.55E−01 2 Unchanged Medium O43660 827.0995 1.13E−01 3.27E−01 2 Unchanged Medium Q15155 525.8869 −4.38E−01 −6.51E−01 2 Unchanged Medium Q9H361 653.8286 −9.52E−02 −6.29E−01 2 Unchanged Medium Q15366 1857.745 1.26E−01 −3.86E−01 2 Unchanged Medium P19388 593.4201 3.39E−01 −6.12E−02 2 Unchanged Medium P52434 1211.761 3.50E−01 6.35E−01 2 Unchanged Medium P36954 1613.004 −1.82E−01 1.84E−01 2 Unchanged Medium P53803 619.6184 2.70E−01 1.03E+00 2 Unchanged Medium Q9UQQ3 558.9966 1.98E−01 4.25E−01 2 Unchanged Medium Q13670 708.0473 −6.11E−01 −6.07E−02 2 Unchanged Medium Q9P0J7 1438.482 −2.33E−01 2.97E−01 2 Unchanged Medium O60925 1737.289 1.89E−01 7.51E−02 2 Unchanged Medium Q9UHV9 743.3158 6.95E−01 7.78E−01 2 Unchanged Medium Q13519 638.4071 6.53E−01 −2.83E−01 2 Unchanged Medium P04156 710.1438 −1.85E−01 −3.39E−01 2 Unchanged Medium Q9UI73 504.0018 3.45E−01 3.13E−01 2 Unchanged Medium Q9P0T3 1820.221 1.02E+00 3.83E−01 2 Unchanged Medium Q02809 991.2271 1.98E+00 −7.97E−02 2 Unchanged Medium P07237 538.3489 −1.39E−01 −6.44E−01 2 Unchanged Medium P09466 567.0247 9.49E−01 7.68E−01 2 Unchanged Medium Q16342 661.3332 −5.84E−01 4.52E−02 2 Unchanged Medium O75340 1167.782 3.62E−01 4.70E−02 2 Unchanged Medium P35232 1818.121 −3.54E−01 −1.78E−01 2 Unchanged Medium Q9UQ80 1763.59 7.44E−02 −4.58E−01 2 Unchanged Medium Q12796 1643.691 −3.85E−01 −3.36E−01 2 Unchanged Medium Q15188 1232.034 4.93E−01 3.76E−01 2 Unchanged Medium P35998 1090.401 6.85E−02 2.49E−01 2 Unchanged Medium P47210 127.919 2.02E−01 1.53E−01 2 Unchanged Medium O00495 701.7628 −8.89E−01 −1.07E+00 2 Unchanged Medium O75831 630.7237 −5.92E−01 −2.97E−01 2 Unchanged Medium Q13200 523.3702 −9.59E−01 −1.16E−01 2 Unchanged Medium O43242 1675.386 −3.99E−01 −8.13E−01 2 Unchanged Medium P55036 591.0419 3.53E−01 6.51E−01 2 Unchanged Medium P48556 1317.42 4.42E−01 −2.72E−01 2 Unchanged Medium Q92530 1724.253 −3.24E−03 −2.04E−01 2 Unchanged Medium P28066 769.7417 1.62E−02 1.46E−03 2 Unchanged Medium O14818 1308.162 −1.24E−01 3.12E−01 2 Unchanged Medium P49721 1853.89 −1.81E−01 2.04E−01 2 Unchanged Medium P28062 735.864 −6.58E−01 1.82E−01 2 Unchanged Medium P28065 1133.626 3.79E−01 1.08E+00 2 Unchanged Medium P10619 1142.279 −6.51E−01 −7.62E−01 2 Unchanged Medium Q9UNN8 694.2014 −8.69E−01 −3.46E−01 2 Unchanged Medium Q15084 782.4339 −3.32E−01 −1.41E+00 2 Unchanged Medium Q9Y2B9 814.4047 2.13E−01 6.73E−01 2 Unchanged Medium Q13517 532.9442 7.27E−01 6.25E−01 2 Unchanged Medium P54619 632.0978 8.01E−01 2.45E−01 2 Unchanged Medium P17612 724.5168 4.87E−01 −3.19E−02 2 Unchanged Medium P09131 584.2407 2.22E−01 1.98E−01 2 Unchanged Medium O60927 1630.486 −2.99E−01 2.42E−02 2 Unchanged Medium P41236 578.9436 1.34E−01 2.23E−01 2 Unchanged Medium Q15435 784.0242 2.48E−01 6.01E−01 2 Unchanged Medium P05323 992.192 −4.10E−01 8.39E−02 2 Unchanged Medium Q15257 996.8116 3.26E−01 −3.29E−02 2 Unchanged Medium P33172 1357.256 −7.51E−01 −5.59E−01 2 Unchanged Medium O00743 936.2693 −4.35E−01 1.02E−01 2 Unchanged Medium P38391 1175.447 4.45E−01 −9.93E−04 2 Unchanged Medium P78324 657.1953 −1.12E−01 2.13E−01 2 Unchanged Medium Q13332 1928.827 1.02E−01 1.57E−03 2 Unchanged Medium Q9HAD6 981.1143 1.46E−01 −9.50E−02 2 Unchanged Medium O43445 631.8368 −4.49E−01 −5.01E−01 2 Unchanged Medium Q9Y6B3 794.9108 6.62E−01 1.04E−01 2 Unchanged Medium Q9HAN1 1019.233 3.14E−01 4.71E−01 2 Unchanged Medium Q9NQA4 727.7123 −1.31E−01 3.70E−02 2 Unchanged Medium O43598 517.9666 −4.41E−02 3.90E−01 2 Unchanged Medium O43257 1183.655 1.48E−01 9.40E−02 2 Unchanged Medium Q9NY06 693.4947 −7.62E−01 −8.29E−01 2 Unchanged Medium P17152 547.029 5.64E−01 7.00E−01 2 Unchanged Medium Q9Y6I9 533.7168 9.92E−01 3.79E−01 2 Unchanged Medium P54886 538.0842 1.16E+00 −4.31E−01 2 Unchanged Medium Q13876 718.0657 1.45E−01 −3.50E−01 2 Unchanged Medium O14679 839.1208 −1.26E−01 7.02E−01 2 Unchanged Medium P53611 807.7755 3.08E−01 −6.14E−02 2 Unchanged Medium P47224 693.8748 −1.61E−01 4.11E−01 2 Unchanged Medium Q15907 1060.693 4.02E−01 1.53E−01 2 Unchanged Medium P51153 895.2783 8.70E−01 5.95E−01 2 Unchanged Medium P35287 571.2023 1.08E−01 1.02E−01 2 Unchanged Medium Q9NP72 629.3713 4.66E−01 7.89E−01 2 Unchanged Medium P11476 933.4801 −6.51E−02 −4.38E−01 2 Unchanged Medium Q9H0U4 638.0939 4.02E−01 3.90E−01 2 Unchanged Medium P08886 1858.384 5.65E−01 3.54E−01 2 Unchanged Medium O95716 701.181 −7.08E−01 −5.10E−01 2 Unchanged Medium P35239 566.5496 −6.05E−01 2.42E−01 2 Unchanged Medium P20340 524.9788 −2.72E−01 3.81E−01 2 Unchanged Medium P43487 1468.585 3.13E−01 −2.84E−01 2 Unchanged Medium Q9UI26 1319.368 −2.41E−01 −3.52E−01 2 Unchanged Medium P47736 583.6391 −9.25E−01 −1.08E+00 2 Unchanged Medium Q15382 1754.23 1.88E−01 6.10E−01 2 Unchanged Medium P52199 816.6152 −4.22E−01 1.50E+00 2 Unchanged Medium P35238 971.4616 −4.48E−03 −2.29E−01 2 Unchanged Medium Q14644 622.1475 2.58E−02 1.74E−02 2 Unchanged Medium Q15404 1925.544 5.86E−01 3.11E−01 2 Unchanged Medium Q13283 735.5498 −5.68E−01 −1.02E−01 2 Unchanged Medium Q9NVQ9 1286.027 −9.24E−03 −1.56E−01 2 Unchanged Medium O60895 663.6562 6.51E−01 −1.43E−01 2 Unchanged Medium P35244 656.7974 7.65E−01 −1.16E−01 2 Unchanged Medium Q99623 1020.486 1.14E−01 −7.25E−01 2 Unchanged Medium Q9UMQ4 725.1999 6.36E−02 −3.53E−01 2 Unchanged Medium Q9NQC3 991.1835 −6.53E−01 −1.32E+00 2 Unchanged Medium P47804 509.1489 6.38E−01 3.02E−01 2 Unchanged Medium Q16576 1250.347 −9.46E−01 −1.23E−01 2 Unchanged Medium O95357 532.4837 −1.71E+00 7.14E−02 2 Unchanged Medium Q15299 1017.603 −6.51E−02 −1.15E−01 2 Unchanged Medium Q9UMY1 641.044 −5.86E−02 2.51E−01 2 Unchanged Medium Q13017 627.5049 −1.23E−01 5.27E−01 2 Unchanged Medium O43182 986.3979 −4.89E−01 −6.41E−01 2 Unchanged Medium O60274 531.8448 −8.31E−01 −1.76E−01 2 Unchanged Medium P07998 1976.991 2.99E−01 1.23E+00 2 Unchanged Medium P04843 1700.316 5.90E−01 −1.37E−01 2 Unchanged Medium P04844 1540.461 2.56E−01 −4.32E−01 2 Unchanged Medium P26373 1739.922 −1.20E−01 −7.97E−01 2 Unchanged Medium P40429 1694.794 −8.21E−01 9.89E−02 2 Unchanged Medium P39019 1841.785 3.29E−01 −2.81E−01 2 Unchanged Medium P78317 695.4611 −1.77E−01 −1.93E−01 2 Unchanged Medium Q99942 1030.595 1.47E−01 −1.00E−01 2 Unchanged Medium O43148 564.3647 −5.52E−01 3.50E−01 2 Unchanged Medium O02916 530.87 −3.10E−01 2.36E−01 2 Unchanged Medium Q9Y580 545.5838 5.97E−01 9.45E−01 2 Unchanged Medium Q14621 581.142 2.08E−02 5.61E−01 2 Unchanged Medium Q93062 714.6837 −4.00E−01 −3.60E−01 2 Unchanged Medium Q99497 1958.111 4.21E−01 −4.56E−01 2 Unchanged Medium Q99584 529.713 4.55E−01 −2.25E−01 2 Unchanged Medium P23526 544.258 −2.02E−01 1.32E−01 2 Unchanged Medium O43865 817.8431 −1.65E+00 −1.47E+00 2 Unchanged Medium O14826 534.3923 −4.57E−01 −5.24E−01 2 Unchanged Medium O75326 835.2276 2.46E−01 −5.09E−02 2 Unchanged Medium O43278 1066.162 −1.01E+00 −3.74E−02 2 Unchanged Medium O00271 1332.552 −6.55E−01 3.36E−01 2 Unchanged Medium Q9UEW8 1032.185 −5.48E−01 −2.63E−01 2 Unchanged Medium Q13043 781.5546 1.04E−02 1.58E−01 2 Unchanged Medium Q9Y282 1448.986 5.76E−01 −1.41E−01 2 Unchanged Medium P35542 959.3499 1.05E−01 7.98E−01 2 Unchanged Medium O75790 779.5745 6.97E−02 3.16E−02 2 Unchanged Medium Q9P0V3 1483.624 3.54E−01 5.04E−01 2 Unchanged Medium Q99519 630.4428 −5.15E−01 −6.70E−02 2 Unchanged Medium Q92185 520.9105 −4.28E−01 −3.82E−01 2 Unchanged Medium Q9Y6A9 692.8575 9.83E−01 7.24E−01 2 Unchanged Medium P21378 626.0198 2.16E−01 −2.91E−01 2 Unchanged Medium O15302 899.9534 −3.06E−01 −3.47E−01 2 Unchanged Medium O76094 1286.822 −5.12E−02 −6.11E−01 2 Unchanged Medium Q9UNL2 1085.128 5.24E−01 −1.35E+00 2 Unchanged Medium P40763 521.4351 −9.48E−01 −3.02E−01 2 Unchanged Medium Q92783 857.8322 −1.90E−01 3.01E−01 2 Unchanged Medium Q9H723 846.2392 7.47E−01 −5.00E−01 2 Unchanged Medium O15258 759.8427 3.93E−01 −1.63E−01 2 Unchanged Medium O14834 786.0877 3.66E−01 1.03E−01 2 Unchanged Medium O43617 1650.871 −2.85E−01 −7.94E−03 2 Unchanged Medium Q04837 1064.292 −2.89E−01 −5.00E−01 2 Unchanged Medium P05455 841.9268 1.29E−01 −1.93E−01 2 Unchanged Medium P43331 1073.82 1.86E−01 4.63E−01 2 Unchanged Medium P09012 514.5708 3.23E−01 −8.22E−01 2 Unchanged Medium P08579 581.0279 4.15E−01 1.83E−01 2 Unchanged Medium P09234 1269.64 3.05E−01 4.62E−01 2 Unchanged Medium P08578 1819.876 −6.41E−02 −1.28E−01 2 Unchanged Medium Q15357 570.2015 6.35E−01 9.41E−01 2 Unchanged Medium P14678 1686.175 −2.29E−01 −6.65E−01 2 Unchanged Medium Q13487 616.6789 3.24E−01 4.03E−01 2 Unchanged Medium P35326 721.2318 1.53E+00 1.83E+00 2 Unchanged Medium P55854 804.107 2.82E−01 −2.67E−01 2 Unchanged Medium P14648 1839.36 7.90E−02 5.18E−01 2 Unchanged Medium P55011 616.497 −1.94E−01 3.23E−01 2 Unchanged Medium O95258 523.9535 2.79E−01 1.20E−01 2 Unchanged Medium O15431 1336.855 5.27E−01 −2.77E−01 2 Unchanged Medium P04920 1624.765 7.81E−02 −5.33E−02 2 Unchanged Medium Q01650 832.1088 3.10E−01 −3.99E−01 2 Unchanged Medium Q07890 575.1528 5.14E−01 2.51E−01 2 Unchanged Medium O60749 688.5915 1.08E+00 1.35E+00 2 Unchanged Medium O60493 1180.399 2.27E−01 4.22E−01 2 Unchanged Medium Q9Y5X3 670.591 2.63E−02 −6.32E−02 2 Unchanged Medium Q01082 545.8922 −5.62E−01 2.49E−01 2 Unchanged Medium P52788 839.7693 −2.17E−01 −6.78E−02 2 Unchanged Medium P17947 1366.573 3.32E−01 −1.90E−01 2 Unchanged Medium Q14818 609.3662 5.16E−01 −1.34E−01 2 Unchanged Medium Q15427 530.9445 2.92E−01 4.71E−01 2 Unchanged Medium Q15815 614.261 −4.20E−01 −4.18E−01 2 Unchanged Medium Q01130 522.9409 −1.80E−01 −7.18E−02 2 Unchanged Medium P23152 1480.13 −1.16E−01 −7.94E−02 2 Unchanged Medium Q13503 670.5377 2.44E−02 −3.13E−01 2 Unchanged Medium Q9P2R9 522.8318 5.51E−02 1.69E−01 2 Unchanged Medium Q9H6I2 819.674 −1.16E−01 3.24E−01 2 Unchanged Medium Q9BT81 525.7297 1.46E−01 9.25E−02 2 Unchanged Medium O60526 596.1019 −3.78E−01 −3.93E−01 2 Unchanged Medium Q9Y6X1 1700.638 3.87E−01 −4.68E−01 2 Unchanged Medium P31948 500.9139 2.47E−01 3.32E−01 2 Unchanged Medium P21912 785.3111 9.93E−02 3.63E−01 2 Unchanged Medium O14521 601.9355 9.66E−02 −3.18E−01 2 Unchanged Medium P53597 582.7447 −3.48E−01 −5.22E−01 2 Unchanged Medium O95605 569.4163 −8.42E−01 −6.39E−01 2 Unchanged Medium Q16550 1081.744 2.85E−01 8.24E−01 2 Unchanged Medium Q15526 524.7026 3.18E−01 1.56E−01 2 Unchanged Medium O43539 1178.519 2.12E−01 2.85E−01 2 Unchanged Medium Q9UPX1 546.8885 −6.98E−01 −3.51E−01 2 Unchanged Medium O95721 849.1506 −2.75E−01 3.10E−01 2 Unchanged Medium O43391 548.1569 −7.23E−01 3.17E−02 2 Unchanged Medium Q15833 686.0183 3.47E−01 −2.49E−01 2 Unchanged Medium Q92804 847.4936 2.84E−01 −5.30E−01 2 Unchanged Medium Q9Y490 1625.187 8.18E−01 −2.01E−01 2 Unchanged Medium O94797 614.3777 −8.58E−01 −1.01E+00 2 Unchanged Medium Q13311 1004.505 4.15E−02 4.00E−01 2 Unchanged Medium Q16650 1645.184 3.37E−01 3.15E−01 2 Unchanged Medium P51864 1690.282 −4.93E−01 −3.61E−01 2 Unchanged Medium P55061 1615.143 3.56E−01 −2.10E−01 2 Unchanged Medium Q15569 780.661 −2.42E−01 −7.31E−02 2 Unchanged Medium O60636 515.2157 −3.19E−01 5.85E−01 2 Unchanged Medium O60637 770.9441 −9.09E−01 −4.68E−01 2 Unchanged Medium O95857 578.9636 −9.67E−01 −5.58E−02 2 Unchanged Medium Q99614 744.2616 −1.52E−01 3.35E−01 2 Unchanged Medium Q13118 575.4732 6.07E−01 4.31E−01 2 Unchanged Medium Q15583 1105.268 3.64E−01 5.42E−01 2 Unchanged Medium Q9H3N1 507.428 7.46E−01 5.60E−02 2 Unchanged Medium O43396 1693.179 −2.34E−01 −9.18E−02 2 Unchanged Medium P04216 1541.609 4.61E+00 8.10E−01 2 Unchanged Medium P12956 1353.001 2.51E−01 3.46E−01 2 Unchanged Medium P16035 542.4517 1.34E+00 −2.54E−02 2 Unchanged Medium Q9H2X8 1033.648 9.65E−01 5.00E−01 2 Unchanged Medium Q13077 1097.404 −7.42E−01 6.49E−03 2 Unchanged Medium Q9NZ34 1148.575 2.58E−01 1.69E−02 2 Unchanged Medium Q15369 854.8396 −1.55E−01 5.11E−01 2 Unchanged Medium Q15906 608.5936 1.01E+00 2.25E−01 2 Unchanged Medium P50616 760.3803 −7.78E−01 −2.40E−02 2 Unchanged Medium Q13595 519.219 1.50E+00 1.31E+00 2 Unchanged Medium P37802 1798.473 −7.60E−01 1.70E−01 2 Unchanged Medium Q9Y5Z9 1108.824 −2.33E−01 −5.97E−01 2 Unchanged Medium Q99595 521.2602 −6.87E−03 5.60E−01 2 Unchanged Medium O60830 1744.175 2.75E−01 −4.77E−02 2 Unchanged Medium O14925 737.451 −1.91E−01 1.25E−01 2 Unchanged Medium Q9Y5J9 1615.991 1.06E−02 −7.98E−02 2 Unchanged Medium Q15629 897.0752 −6.84E−01 8.48E−02 2 Unchanged Medium Q99442 788.001 1.02E+00 5.51E−01 2 Unchanged Medium Q99805 1081.028 −9.63E−02 3.03E−01 2 Unchanged Medium Q9Y2B0 995.6424 5.33E−01 9.54E−01 2 Unchanged Medium P49755 827.066 −9.04E−01 −1.48E+00 2 Unchanged Medium 930.4505 −9.59E−01 −6.15E−01 2 Unchanged Medium Q03519 701.534 −3.22E−01 −5.72E−01 2 Unchanged Medium Q9NWF9 599.4053 4.83E−02 −5.86E−01 2 Unchanged Medium Q15656 1792.501 −1.54E−02 −1.95E−01 2 Unchanged Medium Q92734 1624.429 1.50E−01 3.23E−01 2 Unchanged Medium Q12815 879.96 −1.85E−01 4.15E−01 2 Unchanged Medium P09493 807.373 2.43E−02 −1.20E+00 2 Unchanged Medium P49411 519.255 −1.42E−01 7.90E−02 2 Unchanged Medium P05217 942.8088 −3.87E−01 −7.73E−01 2 Unchanged Medium P23258 1702.331 3.10E−01 −5.03E−01 2 Unchanged Medium Q9UBN6 584.4772 1.75E−01 6.74E−01 2 Unchanged Medium Q13829 731.2933 −6.20E−01 −1.01E−01 2 Unchanged Medium O00496 661.0848 3.50E−01 −1.82E−01 2 Unchanged Medium Q99816 705.4904 −2.07E−01 8.08E−02 2 Unchanged Medium P16422 870.9367 −1.95E+00 −8.73E−01 2 Unchanged Medium Q9NP84 583.2792 −3.04E−01 −4.75E−01 2 Unchanged Medium Q9UJ47 807.3703 3.05E−02 4.69E−02 2 Unchanged Medium P31946 966.9847 −7.52E−01 −3.55E−01 2 Unchanged Medium P35214 850.9964 −3.68E−01 1.67E−01 2 Unchanged Medium P27348 1615.078 −9.91E−01 −5.08E−01 2 Unchanged Medium O60704 547.7036 5.96E−02 −1.14E+00 2 Unchanged Medium Q9Y4Z0 813.8478 1.28E−01 −2.81E−01 2 Unchanged Medium P14927 922.1475 −6.04E−02 −2.85E−01 2 Unchanged Medium Q9UI02 1320.75 6.97E−01 6.16E−01 2 Unchanged Medium P31930 794.0747 −3.01E−01 3.33E−03 2 Unchanged Medium P22695 562.0633 3.12E−01 4.40E−01 2 Unchanged Medium P07919 1382.391 −4.02E−01 4.49E−01 2 Unchanged Medium P47985 1306.086 −4.31E−01 −2.58E−01 2 Unchanged Medium Q9NZ09 1598.619 −1.90E−01 1.93E−01 2 Unchanged Medium Q9UNP0 538.3523 1.86E−01 −9.48E−02 2 Unchanged Medium Q9UHP3 613.0845 1.94E−02 3.85E−01 2 Unchanged Medium P22314 1788.503 4.71E−03 −1.75E−01 2 Unchanged Medium Q13404 1138.559 7.28E−02 1.77E−01 2 Unchanged Medium P51669 1247.427 −1.09E−01 4.05E−02 2 Unchanged Medium P47986 567.8765 −1.19E−01 −2.47E−01 2 Unchanged Medium O14933 735.6835 −2.66E−01 3.16E−01 2 Unchanged Medium Q16781 757.964 −7.91E−01 −1.78E−01 2 Unchanged Medium Q93068 1399.48 −8.84E−02 1.51E−01 2 Unchanged Medium Q15386 596.8686 2.40E−01 2.45E−01 2 Unchanged Medium Q9UBK9 1125.743 5.65E−01 1.74E−01 2 Unchanged Medium O60512 529.5839 3.12E−01 4.81E−01 2 Unchanged Medium P78383 1816.963 4.74E−01 1.15E−01 2 Unchanged Medium Q16851 1302.468 −5.79E−03 −6.64E−02 2 Unchanged Medium Q9NZ45 672.9895 9.52E−02 3.98E−02 2 Unchanged Medium Q9NZ32 1214.412 3.87E−01 2.75E−01 2 Unchanged Medium Q9NZ29 923.518 7.62E−01 5.89E−01 2 Unchanged Medium Q15853 644.9023 2.14E−01 7.78E−02 2 Unchanged Medium Q92528 623.0076 1.54E−01 2.90E−01 2 Unchanged Medium P15692 619.202 8.95E−01 2.27E−01 2 Unchanged Medium P50552 502.9122 −2.55E−01 4.67E−01 2 Unchanged Medium O60763 642.7624 2.21E−01 −2.35E−01 2 Unchanged Medium Q15836 1076.578 3.99E−01 7.63E−01 2 Unchanged Medium Q9UEU0 621.1953 5.76E−01 5.72E−01 2 Unchanged Medium P14921 656.6528 −1.65E+00 −2.57E−01 2 Unchanged Medium P18206 767.5496 5.77E−01 5.62E−01 2 Unchanged Medium P00540 835.5051 −7.49E−01 −6.16E−01 2 Unchanged Medium P01106 514.7639 −4.09E−01 1.61E−01 2 Unchanged Medium P21796 525.9036 2.72E−01 7.47E−02 2 Unchanged Medium Q15765 762.0788 3.70E−01 3.20E−02 2 Unchanged Medium P10398 744.4583 −9.96E−01 −7.32E−01 2 Unchanged Medium P11233 995.8044 3.50E−01 3.17E−01 2 Unchanged Medium Q9Y6W5 1468.514 2.19E−01 3.45E−01 2 Unchanged Medium Q9UPY6 1623.108 5.17E−01 −3.09E−01 2 Unchanged Medium O75083 944.1492 1.10E−01 1.30E−01 2 Unchanged Medium O76071 746.1814 2.60E−01 5.58E−01 2 Unchanged Medium Q9HCN4 923.9753 −1.24E+00 −1.71E−01 2 Unchanged Medium Q9UM05 1672.59 −2.91E−01 −2.50E−01 2 Unchanged Medium Q9UQR1 604.9201 1.34E−01 5.21E−01 2 Unchanged Medium Q14119 1387.253 −2.67E−03 5.57E−01 2 Unchanged Medium Q9NW07 554.3431 7.65E−01 5.15E−01 2 Unchanged Medium P20694 969.9823 −2.84E−01 −4.49E−02 2 Unchanged Medium

Claims

1-10. (canceled)

11. An isolated insulin-producing cell generated by a method comprising the step of culturing an IP cell in a cell culture medium comprising an effective amount of at least one differentiation promoting factor selected from the group consisting of C-Natriuretic Peptide (CNP), Calcitonin Gene Related Peptide, Cholera Toxin B Subunit, Dexamethasone, Gastrin-Releasing Peptide, Laminin, Met-Enkephalin, PDGFAA+PDGFBB, Sonic Hedgehog, and Substance P, such that the IP cell is transformed into an insulin-producing cell.

12. An insulin-producing cell, prepared by differentiating a mammalian acinar cell in vitro, wherein said insulin-producing cell has an expression profile after 16 days ex vivo as shown in Table 6.

13-20. (canceled)

Patent History
Publication number: 20060275900
Type: Application
Filed: Apr 26, 2006
Publication Date: Dec 7, 2006
Applicants: Becton, Dickinson and Company (Franklin Lakes, NJ), Novocell, Inc. (Irvine, CA)
Inventors: Sharon Presnell (Raleigh, NC), Mohammad Heidaran (Cary, NC), Perry Haaland (Chapel Hill, NC), David Scharp (Mission Viejo, CA), Paul Latta (Irvine, CA), Margaret Coutts (Irvine, CA), Catherine McIntyre (Aliso Viejo, CA)
Application Number: 11/410,954
Classifications
Current U.S. Class: 435/366.000; 514/12.000
International Classification: C12N 5/08 (20060101); A61K 38/17 (20060101);