Bio-Medical Unit with Wireless Signaling Micro-Electromechanical Module
A bio-medical unit includes a power harvesting module and first and second micro-electro mechanical modules. The power harvesting module is operable to generate a supply voltage from an electromagnetic source signal. The first micro-electro mechanical module is powered by the supply voltage and transmits a wireless signal. The second micro-electro mechanical module is powered by the supply voltage and receives the wireless signal. The bio-medical unit is of a size for implanting into a host body, wherein, when implanted, the bio-medical unit is positioned proximal to monitor fluid flow in the host body based on the transmitting and receiving of the wireless signal.
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This patent application is claiming priority under 35 USC §119 to a provisionally filed patent application entitled BIO-MEDICAL UNIT AND APPLICATIONS THEREOF, having a provisional filing date of Sep. 30, 2009, and a provisional Ser. No. 61/247,060.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENTNOT APPLICABLE
INCORPORATION-BY-REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISCNOT APPLICABLE
BACKGROUND OF THE INVENTION1. Technical Field of the Invention
This invention relates generally to medical equipment and more particularly to wireless medical equipment.
2. Description of Related Art
As is known, there is a wide variety of medical equipment that aids in the diagnosis, monitoring, and/or treatment of patients' medical conditions. For instances, there are diagnostic medical devices, therapeutic medical devices, life support medical devices, medical monitoring devices, medical laboratory equipment, etc. As specific exampled magnetic resonance imaging (MRI) devices produce images that illustrate the internal structure and function of a body.
The advancement of medical equipment is in step with the advancements of other technologies (e.g., radio frequency identification (RFID), robotics, etc.). Recently, RFID technology has been used for in vitro use to store patient information for easy access. While such in vitro applications have begun, the technical advancement in this area is in its infancy.
Therefore, a need exists for a bio-medical unit that has applications within artificial body part implants.
BRIEF SUMMARY OF THE INVENTIONThe present invention is directed to apparatus and methods of operation that are further described in the following Brief Description of the Drawings, the Detailed Description of the Invention, and the claims. Other features and advantages of the present invention will become apparent from the following detailed description of the invention made with reference to the accompanying drawings.
In operation, a transmitter 12 emits electromagnetic signals 16 that pass through the body and are received by a receiver 14. The transmitter 12 and receiver 14 may be part of a piece of medical diagnostic equipment (e.g., magnetic resonance imaging (MRI), X-ray, etc.) or independent components for stimulating and communicating with the network of bio-medical units in and/or on a body. One or more of the bio-medical units 10 receives the transmitted electromagnetic signals 16 and generates a supply voltage therefrom. Examples of this will be described in greater detail with reference to
Embedded within the electromagnetic signals 16 (e.g., radio frequency (RF) signals, millimeter wave (MMW) signals, MRI signals, etc.) or via separate signals, the transmitter 12 communicates with one or more of the bio-medical units 10. For example, the electromagnetic signals 16 may have a frequency in the range of a few MHz to 900 MHz and the communication with the bio-medical units 10 is modulated on the electromagnetic signals 16 at a much higher frequency (e.g., 5 GHz to 300 GHz). As another example, the communication with the bio-medical units 10 may occur during gaps (e.g., per protocol of medical equipment or injected for communication) of transmitting the electromagnetic signals 16. As another example, the communication with the bio-medical units 10 occurs in a different frequency band and/or using a different transmission medium (e.g., use RF or MMW signals when the magnetic field of the electromagnetic signals are dominate, use ultrasound signals when the electromagnetic signals 16 are RF and/or MMW signals, etc.).
One or more of the bio-medical units 10 receives the communication signals 18 and processes them accordingly. The communication signals 18 may be instructions to collect data, to transmit collected data, to move the unit's position in the body, to perform a function, to administer a treatment, etc. If the received communication signals 18 require a response, the bio-medical unit 10 prepares an appropriate response and transmits it to the receiver 14 using a similar communication convention used by the transmitter 12.
One or more of the bio-medical units 10 powers itself by harvesting energy from the magnetic field 26 or changes thereof as produced by gradient coils, from the magnetic fields of the MRI signals 28, from the electrical fields of the MRI signals 28, and/or from the electromagnetic aspects of the MRI signals 28. A unit 10 converts the harvested energy into a supply voltage that supplies other components of the unit (e.g., a communication module, a processing module, memory, a functional module, etc.).
A communication device 24 communicates data and/or control communications 30 with one or more of the bio-medical units 10 over one or more wireless links. The communication device 24 may be a separate device from the MRI machine or integrated into the MRI machine. For example, the communication device 24, whether integrated or separate, may be a cellular telephone, a computer with a wireless interface (e.g., a WLAN station and/or access point, Bluetooth, a proprietary protocol, etc.), etc. A wireless link may be one or more frequencies in the ISM band, in the 60 GHz frequency band, the ultrasound frequency band, and/or other frequency bands that supports one or more communication protocols (e.g., data modulation schemes, beamforming, RF or MMW modulation, encoding, error correction, etc.).
The composition of the bio-medical units 10 includes non-ferromagnetic materials (e.g., paramagnetic or diamagnetic) and/or metal alloys that are minimally affected by an external magnetic field 26. In this regard, the units harvest power from the MRI signals 28 and communicate using RF and/or MMW electromagnetic signals with negligible chance of encountering the projectile or missile effect of implants that include ferromagnetic materials.
In this system, one or more bio-medical units 10 are implanted in, or affixed to, a host body (e.g., a person, an animal, genetically grown tissue, etc.). As previously discussed and will be discussed in greater detail with reference to one or more of the following figures, a bio-medical unit includes a power harvesting module, a communication module, and one or more functional modules. The power harvesting module operable to produce a supply voltage from a received electromagnetic power signal (e.g., the electromagnetic signal 16 of
In an example of operation, the communication device 24 (e.g., integrated into an MRI machine, a cellular telephone, a computer with a wireless interface, etc.) receives a downstream WAN signal from the network 42 via the WAN communication device 34. The downstream WAN signal may be generated by a remote monitoring device 36, a remote diagnostic device (e.g., computer 38 performing a remote diagnostic function), a remote control device (e.g., computer 38 performing a remote control function), and/or a medical record storage device (e.g., database 40).
The communication device 24 converts the downstream WAN signal into a downstream data signal. For example, the communication device 24 may convert the downstream WAN signal into a symbol stream in accordance with one or more wireless communication protocols (e.g., GSM, CDMA, WCDMA, HSUPA, HSDPA, WiMAX, EDGE, GPRS, IEEE 802.11, Bluetooth, ZigBee, universal mobile telecommunications system (UMTS), long term evolution (LTE), IEEE 802.16, evolution data optimized (EV-DO), etc.). The communication device 24 may convert the symbol stream into the downstream data signal using the same or a different wireless communication protocol.
Alternatively, the communication device 24 may convert the symbol stream into data that it interprets to determine how to structure the communication with the bio-medical unit 10 and/or what data (e.g., instructions, commands, digital information, etc.) to include in the downstream data signal. Having determined how to structure and what to include in the downstream data signal, the communication device 24 generates the downstream data signal in accordance with one or more wireless communication protocols. As yet another alternative, the communication device 24 may function as a relay, which provides the downstream WAN signal as the downstream data signal to the one or more bio-medical units 10.
When the communication device 24 has (and/or is processing) the downstream data signal to send to the bio-medical unit, it sets up a communication with the bio-medical unit. The set up may include identifying the particular bio-medical unit(s), determining the communication protocol used by the identified bio-medical unit(s), sending a signal to an electromagnetic device (e.g., MRI device, etc.) to request that it generates the electromagnetic power signal to power the bio-medical unit, and/or initiate a communication in accordance with the identified communication protocol. As an alternative to requesting a separate electromagnetic device to create the electromagnetic power signal, the communication device may include an electromagnetic device to create the electromagnetic power signal.
Having set up the communication, the communication device 24 wirelessly communicates the downstream data signal to the communication module of the bio-medical unit 10. The functional module of the bio-medical unit 10 processes the downstream data contained in the downstream data signal to perform a bio-medical functional, to store digital information contained in the downstream data, to administer a treatment (e.g., administer a medication, apply laser stimulus, apply electrical stimulus, etc.), to collect a sample (e.g., blood, tissue, cell, etc.), to perform a micro electro-mechanical function, and/or to collect data. For example, the bio-medical function may include capturing a digital image, capturing a radio frequency (e.g., 300 MHz to 300 GHz) radar image, an ultrasound image, a tissue sample, and/or a measurement (e.g., blood pressure, temperature, pulse, blood-oxygen level, blood sugar level, etc.).
When the downstream data requires a response, the functional module performs a bio-medical function to produce upstream data. The communication module converts the upstream data into an upstream data signal in accordance with the one or more wireless protocols. The communication device 24 converts the upstream data signal into an upstream wide area network (WAN) signal and transmits it to a remote diagnostic device, a remote control device, and/or a medical record storage device. In this manner, a person(s) operating the remote monitors 36 may view images and/or the data 30 gathered by the bio-medical units 10. This enables a specialist to be consulted without requiring the patient to travel to the specialist's office.
In another example of operation, one or more of the computers 38 may communicate with the bio-medical units 10 via the communication device 24, the WAN communication device 34, and the network 42. In this example, the computer 36 may provide commands 30 to one or more of the bio-medical units 10 to gather data, to dispense a medication, to move to a new position in the body, to perform a mechanical function (e.g., cut, grasp, drill, puncture, stitch, patch, etc.), etc. As such, the bio-medical units 10 may be remotely controlled via one or more of the computers 36.
In another example of operation, one or more of the bio-medical units 10 may read and/or write data from or to one or more of the databases 40. For example, data (e.g., a blood sample analysis) generated by one or more of the bio-medical units 10 may be written to one of the databases 40. The communication device 24 and/or one of the computers 36 may control the writing of data to or the reading of data from the database(s) 40. The data may further include medical records, medical images, prescriptions, etc.
The power harvesting module 46 may generate one or more supply voltages 56 (Vdd) from a power source signal (e.g., one or more of MRI electromagnetic signals 16, magnetic fields 26, RF signals, MMW signals, ultrasound signals, light signals, and body motion). The power harvesting module 46 may be implemented as disclosed in U.S. Pat. No. 7,595,732 to generate one or more supply voltages from an RF signal. The power harvesting module 46 may be implemented as shown in one or more
In an example of operation, a receiver section of the communication module 48 receives an inbound wireless communication signal 60 and converts it into an inbound symbol stream. For example, the receiver section amplifies an inbound wireless (e.g., RF or MMW) signal 60 to produce an amplified inbound RF or MMW signal. The receiver section may then mix in-phase (I) and quadrature (Q) components of the amplified inbound RF or MMW signal with in-phase and quadrature components of a local oscillation to produce a mixed I signal and a mixed Q signal. The mixed I and Q signals are combined to produce an inbound symbol stream. In this embodiment, the inbound symbol may include phase information (e.g., +/−Δθ [phase shift] and/or θ(t) [phase modulation]) and/or frequency information (e.g., +/−Δf [frequency shift] and/or f(t) [frequency modulation]). In another embodiment and/or in furtherance of the preceding embodiment, the inbound RF or MMW signal includes amplitude information (e.g., +/−ΔA [amplitude shift] and/or A(t) [amplitude modulation]). To recover the amplitude information, the receiver section includes an amplitude detector such as an envelope detector, a low pass filter, etc.
The processing module 50 converts the inbound symbol stream into inbound data and generates a command message based on the inbound data. The command message may instruction one or more of the functional modules to perform one or more electro-mechanical functions of gathering data (e.g., imaging data, flow monitoring data), dispensing a medication, moving to a new position in the body, performing a mechanical function (e.g., cut, grasp, drill, puncture, stitch, patch, etc.), dispensing a treatment, collecting a biological sample, etc.
To convert the inbound symbol stream into the inbound data (e.g., voice, text, audio, video, graphics, etc.), the processing module 50 may perform one or more of: digital intermediate frequency to baseband conversion, time to frequency domain conversion, space-time-block decoding, space-frequency-block decoding, demodulation, frequency spread decoding, frequency hopping decoding, beamforming decoding, constellation demapping, deinterleaving, decoding, depuncturing, and/or descrambling. Such a conversion is typically prescribed by one or more wireless communication standards (e.g., GSM, CDMA, WCDMA, HSUPA, HSDPA, WiMAX, EDGE, GPRS, IEEE 802.11, Bluetooth, ZigBee, universal mobile telecommunications system (UMTS), long term evolution (LTE), IEEE 802.16, evolution data optimized (EV-DO), etc.).
The processing module 50 provides the command message to one or more of the micro-electromechanical functional modules 54. The functional module 54 performs an electro-mechanical function within a hosting body in accordance with the command message. Such an electro-mechanical function includes at least one of data gathering (e.g., image, flow monitoring), motion, repairs, dispensing medication, biological sampling, diagnostics, applying laser treatment, applying ultrasound treatment, grasping, sawing, drilling, providing an electronic stimulus etc. Note that the functional modules 54 may be implemented using nanotechnology and/or microelectronic mechanical systems (MEMS) technology.
When requested per the command message (e.g. gather data and report the data), the micro electro-mechanical functional module 54 generates an electro-mechanical response based on the performing the electro-mechanical function. For example, the response may be data (e.g., heart rate, blood sugar levels, temperature, blood flow rate, image of a body object, etc.), a biological sample (e.g., blood sample, tissue sample, etc.), acknowledgement of performing the function (e.g., acknowledge a software update, storing of data, etc.), and/or any appropriate response. The micro electro-mechanical functional module 54 provides the response to the processing module 50.
The processing module 50 converts the electro-mechanical response into an outbound symbol stream, which may be done in accordance with one or more wireless communication standards (e.g., GSM, CDMA, WCDMA, HSUPA, HSDPA, WiMAX, EDGE, GPRS, IEEE 802.11, Bluetooth, ZigBee, universal mobile telecommunications system (UMTS), long term evolution (LTE), IEEE 802.16, evolution data optimized (EV-DO), etc.). Such a conversion includes one or more of: scrambling, puncturing, encoding, interleaving, constellation mapping, modulation, frequency spreading, frequency hopping, beamforming, space-time-block encoding, space-frequency-block encoding, frequency to time domain conversion, and/or digital baseband to intermediate frequency conversion.
A transmitter section of the communication module 48 converts an outbound symbol stream into an outbound RF or MMW signal 60 that has a carrier frequency within a given frequency band (e.g., 900 MHz, 2.5 GHz, 5 GHz, 57-66 GHz, etc.). In an embodiment, this may be done by mixing the outbound symbol stream with a local oscillation to produce an up-converted signal. One or more power amplifiers and/or power amplifier drivers amplifies the up-converted signal, which may be RF or MMW bandpass filtered, to produce the outbound RF or MMW signal 60. In another embodiment, the transmitter section includes an oscillator that produces an oscillation. The outbound symbol stream provides phase information (e.g., +/−Δθ [phase shift] and/or θ(t) [phase modulation]) that adjusts the phase of the oscillation to produce a phase adjusted RF or MMW signal, which is transmitted as the outbound RF signal 60. In another embodiment, the outbound symbol stream includes amplitude information (e.g., A(t) [amplitude modulation]), which is used to adjust the amplitude of the phase adjusted RF or MMW signal to produce the outbound RF or MMW signal 60.
In yet another embodiment, the transmitter section includes an oscillator that produces an oscillation. The outbound symbol provides frequency information (e.g., +/−Δf [frequency shift] and/or f(t) [frequency modulation]) that adjusts the frequency of the oscillation to produce a frequency adjusted RF or MMW signal, which is transmitted as the outbound RF or MMW signal 60. In another embodiment, the outbound symbol stream includes amplitude information, which is used to adjust the amplitude of the frequency adjusted RF or MMW signal to produce the outbound RF or MMW signal 60. In a further embodiment, the transmitter section includes an oscillator that produces an oscillation. The outbound symbol provides amplitude information (e.g., +/−ΔA [amplitude shift] and/or A(t) [amplitude modulation) that adjusts the amplitude of the oscillation to produce the outbound RF or MMW signal 60.
Note that the bio-medical unit 10 may be encapsulated by an encapsulate 58 that is non-toxic to the body. For example, the encapsulate 58 may be a silicon based product, a non-ferromagnetic metal alloy (e.g., stainless steel), etc. As another example, the encapsulate 58 may include a spherical shape and have a ferromagnetic liner that shields the unit from a magnetic field and to offset the forces of the magnetic field. Further note that the bio-medical unit 10 may be implemented on a single die that has an area of a few millimeters or less. The die may be fabricated in accordance with CMOS technology, Gallium-Arsenide technology, and/or any other integrated circuit die fabrication process.
In another example of operation, one of the functional modules 54 functions as a first micro-electro mechanical module and another one of the functions modules 54 functions as a second micro-electro mechanical module. In this example, the bio-medical unit is implanted into a host body (e.g., a person, an animal, a reptile, etc.) at a position proximal to a body object to be monitored and/or have an image taken thereof. For example, the body object may be a vein, an artery, an organ, a cyst (or other growth), etc. As a specific example, the bio-medical unit may be positioned approximately parallel to the flow of blood in a vein, artery, and/or the heart.
When powered by the supply voltage, the first micro-electro mechanical module generates and transmits a wireless signal at, or around, the body object. The second micro-electro mechanical module receives a representation of the wireless signal (e.g., a reflection of the wireless signal, a refraction of the wireless signal, or a determined absorption of the wireless signal). Note that the wireless signal may be an ultrasound signal, a radio frequency signal, and/or a millimeter wave signal.
The processing module 50 may coordinate the transmitting of the wireless signal and the receiving of the representation of the wireless signal. For example, the processing module may receive, via the communication module, a command to enable the transmitting of the wireless signal (e.g., an ultrasound signal) and the receiving of the representation of the wireless signal. In response, the processing module generates a control signal that it provides to the first micro-electro mechanical module to enable it to transmit the wireless signal.
In addition, the processing module may generate flow monitoring data based on the second micro-electro mechanical module receiving of the representation of the wireless signal. As a specific example, the processing module calculates a fluid flow rate based on phase shifting and/or frequency shifting between the transmitting of the wireless signal and the receiving of the representation of the wireless signal. As another specific example, the processing module gathers phase shifting data and/or frequency shifting data based on the transmitting of the wireless signal and the receiving of the representation of the wireless signal.
The processing module may further generate imaging data based on the second micro-electro mechanical module receiving the representation of the wireless signal. As a specific example, the processing module calculates an image of the body object based absorption of the wireless signal by the body object and/or vibration of the body object. As another specific example, the processing module gathers data regarding the absorption of the wireless signal by the body object and/or of the vibration of the body object.
While the preceding examples of a bio-medical unit including first and second micro-electro mechanical modules for transmitting and receiving wireless signals (e.g., ultrasound, RF, MMW, etc.), a bio-medical unit may include one or the other module. For example, a bio-medical unit may include a micro-electro mechanical module for transmitting a wireless signal, where the receiver is external to the body or in another bio-medical unit. As another example, a bio-medical unit may include a micro-electro mechanical module for receiving a representation of a wireless signal, where the transmitter is external to the body or another bio-medical unit.
In an example of operation, the MRI transmitter 20 transmits MRI signals 28 at a frequency of 3-45 MHz at a power level of up to 35 KWatts. The air core inductors 64 are electromagnetically coupled to generate a voltage from the magnetic and/or electric field generated by the MRI signals 28. Alternatively, or in addition to, the air core inductors 64 may generate a voltage from the magnetic field 26 and changes thereof produced by the gradient coils. The rectifying circuit 66 rectifies the AC voltage produced by the inductors to produce a first DC voltage. The regulation circuit generates one or more desired supply voltages 56 from the first DC voltage.
The inductors 64 may be implemented on one more metal layers of the die and include one or more turns per layer. Note that trace thickness, trace length, and other physical properties affect the resulting inductance.
In an example of operation, the MRI transmitter 20 transmits MRI signals 28 at a frequency of 3-45 MHz at a power level of up to 35 KWatts. The air core inductors 70 are electromagnetically coupled to generate a voltage from the magnetic and/or electric field generated by the MRI signals 28. The switching module 72 engages the switches via control signals 74 to couple the inductors 70 in series and/or parallel to generate a desired AC voltage. The rectifier circuit 66 and the capacitor(s) convert the desired AC voltage into the one or more supply voltages 56.
The various embodiments of the power harvesting module 46 may be combined to generate more power, more supply voltages, etc. For example, the embodiment of
The one or more functional modules 54 may perform a repair function, an imaging function, and/or a leakage detection function, which may utilize one or more of a motion propulsion module 96, a camera module 98, a sampling robotics module 100, a treatment robotics module 102, an accelerometer module 104, a flow meter module 106, a transducer module 108, a gyroscope module 110, a high voltage generator module 112, a control release robotics module 114, and/or other functional modules described with reference to one or more other figures. The functional modules 54 may be implemented using MEMS technology and/or nanotechnology. For example, the camera module 98 may be implemented as a digital image sensor in MEMS technology.
The Hall effect communication module 116 utilizes variations in the magnetic field and/or electrical field to produce a plus or minus voltage, which can be encoded to convey information. For example, the charge applied to one or more Hall effect devices 76 may be varied to produce the voltage change. As another example, an MRI transmitter 20 and/or gradient unit may modulate a signal on the magnetic field 26 it generates to produce variations in the magnetic field 26.
In an example of operation, the bio-medical unit 10 recovers power from the electromagnetic (EM) signals 146 transmitted by the MRI transmitter 130 and communicates via MMW signals 148-150 with the MMW transmitter 132 and MMW receiver 136. The MRI transmitter 130 may be part of a portable MRI device, may be part of a full sized MRI machine, and/or part of a separate device for generating EM signals 146 for powering the bio-medical unit 10.
In addition to the MRI transmitter 20 transmitting its signal, a constant magnetic field and various gradient magnetic fields 154-164 are created (one or more in the x dimension Gx, one or more in the y dimension Gy, and one or more in the z direction Gz). The power harvesting module 46 of the bio-medical unit 10 may further use the constant magnetic field and/or the varying magnetic fields 154-164 to create power for the bio-medical unit 10.
During non-transmission periods of the cycle, the bio-medical unit 10 may communicate 168 with the MMW transmitter 132 and/or MMW receiver 136. In this regard, the bio-medical unit 10 alternates from generating power to MMW communication in accordance with the conventional transmission-magnetic field pattern of an MRI machine.
In an example of operation, the MRI transmitter 130 generates an electromagnetic signal that is received by the EM modulator 170. The EM modulator 170 modulates a communication signal on the EM signal to produce an inbound modulated EM signal 176. The EM modulator 170 may modulate (e.g., amplitude modulation, frequency modulation, amplitude shift keying, frequency shift keying, etc.) the magnetic field and/or electric field of the EM signal. In another embodiment, the EM modulator 170 may modulate the magnetic fields produced by the gradient coils to produce the inbound modulated EM signals 176.
The bio-medical unit 10 recovers power from the modulated electromagnetic (EM) signals. In addition, the EM transceiver 174 demodulates the modulated EM signals 178 to recover the communication signal. For outbound signals, the EM transceiver 174 modulates an outbound communication signal to produce outbound modulated EM signals 180. In this instance, the EM transceiver 174 is generating an EM signal that, in air, is modulated on the EM signal transmitted by the transmitter unit 126. In one embodiment, the communication in this system is half duplex such that the modulation of the inbound and outbound communication signals is at the same frequency. In another embodiment, the modulation of the inbound and outbound communication signals are at different frequencies to enable full duplex communication.
In addition to the MRI transmitter 20 transmitting its signal, a constant magnetic field and various gradient magnetic fields are created 154-164 (one or more in the x dimension Gx, one or more in the y dimension Gy, and one or more in the z direction Gz). The power harvesting module 46 of the bio-medical unit 10 may further use the constant magnetic field and/or the varying magnetic fields 154-164 to create power for the bio-medical unit 10.
During the transmission periods of the cycle, the bio-medical unit 10 may communicate via the modulated EM signals 182. In this regard, the bio-medical unit 10 generates power and communicates in accordance with the conventional transmission-magnetic field pattern of an MRI machine.
The bio-medical unit 10 includes a MEMS microphone 262, the communication module 48 for external communications with the communication device 24, the processing module 50, the memory 52, the MEMS electrostatic motor 248, and the power harvesting module 46. In an embodiment the bio-medical unit 10 and communication device 24 communicate directly. In another embodiment, the bio-medical unit 10 and communication device 24 communicate through one or more intermediate networks (e.g., wireline, wireless, cellular, local area wireless, Bluetooth, etc.) The MEMS microphone 262 may include one or more sensors to detect audible sound signals, sub-sonic sound signals, and/or ultrasonic sound signals.
The processing module 50 may produce the processed sounding data based in part on the received sound signals and in part on data in the database 254. The processing module 50 may retrieve data via the communication module 48 and communication device 24 link from the database 254 to assist in the processing of the signals (e.g., pattern matching, filter recommendations, sound field types). The processing module 50 may process the signals to detect objects, masses, air flow, liquid flow, tissue, distances, etc. The processing module 50 may provide the processed sounding data to the speaker 260 for audible interpretation. In another embodiment, the bio-medical unit 10 assists an ultrasound imaging system by relaying ultrasonic sounds from the MEMS microphone 262 to the ultrasound imaging system instead of to the speaker 260.
The MEMS microphone 262 and MEMS speaker 264 may utilize audible sound signals, sub-sonic sound signals, and/or ultrasonic sound signals and may be capable of varying or sweeping sound frequencies across a wide band. The processing module 50 may utilize the MEMS microphone 262 and MEMS speaker 264 to communicate with the other bio-medical unit 10 using pulse code modulation, pulse position modulation, amplitude modulation, frequency modulation, or any other modulation scheme suitable for sound communications. The processing module 50 may multiplex messages utilizing frequency division and/or time division multiplexing.
The bio-medical sound based communications may facilitate communication with one or more other bio-medical units 10. In an embodiment, a star architecture is utilized where one bio-medical unit 10 at the center of the star communicates to a plurality of bio-medical units 10 around the center where each of the plurality of bio-medical units 10 only communicate with the bio-medical unit 10 at the center of the star. In an embodiment, a mesh architecture is utilized where each bio-medical unit 10 communicates as many of the plurality of other bio-medical units 10 as possible and where each of the plurality of bio-medical units 10 may relay messages from one unit to another unit through the mesh.
The processing module 50 may utilize the MEMS microphone 262 and MEMS speaker 264 of one bio-medical unit 10 to reflect sound signals off of matter in the body to determine the composition and position of the matter. In another embodiment, the processing module 50 may utilize the MEMS microphone 262 of one bio-medical unit 10 and the MEMS speaker 264 of a second bio-medical unit 10 to pass sound signals through matter in the body to determine the composition and position of the matter. The processing module 50 may pulse the sound on and off, sweep the sound frequency, vary the amplitude and may use other perturbations to determine the matter composition and location.
The processing module 50 controls the ultrasonic transducer 266 to produce ultrasonic signals and receive resulting reflections from the body object 268. The processing module 50 may coordinate with the processing module 50 of at least one other bio-medical unit 10 to produce ultrasonic signal beams (e.g., constructive simultaneous phased transmissions directed in one direction) and receive resulting reflections from the body object. The processing module 50 may perform the coordination and/or the plurality of processing modules 50 may perform the coordination. In embodiment, the plurality of processing modules 50 receives coordination information via the communication module 48 from at least one other bio-medical unit 10. In another embodiment, the plurality of processing modules 50 receives coordination information via the communication module 48 from an external communication device.
The processing module produces processed ultrasonic signals based on the received ultrasonic reflections from the body object 268. For example, the processed ultrasonic signals may represent a sonogram of the body part. The processing module 50 may send the processed ultrasonic signals to the external communication device and/or to one or more of the plurality of bio-medical units 10.
The bio-medical unit 10 may send a transmitted MMW signal 364 to the body object 268 and receive a reflected MMW signal 366 from the body object. 268. Some of the transmitted MMW signal energy is absorbed, reflected in other directions, and/or transmitted to other directions. The bio-medical unit 10 forms a Doppler radar sequence by varying the frequency of the transmitted MMW signal 364 over a series of transmission steps. The bio-medical unit 10 may determine the distance and location information based on the reflected MMW signal 366 in response to the Doppler radar.
The bio-medical unit 10 may receive a command from the communication device 24 to reposition, adjust the MMW frequency, and transmit MMW signals to perform the Doppler radar function. In another embodiment, the communication device 24 may send a command to a plurality of bio-medical units 10 to coordinate the formation of a beam to better pinpoint the body object. In yet another embodiment, the communication device 24 may send a command to a plurality of bio-medical units 10 to coordinate the Doppler radar function from two, three or more bio-medical units 10 to triangulate the body object location based on the distance information.
The processing module 50 may control the MEMS propulsion 348 to reposition the bio-medical unit 10. The processing module 50 may determine how to control the MMW frequency adjust 358 to affect the distance information detection based on a command, a predetermination, and/or an adaptive algorithm (e.g., that detects course distance ranges at first and fine tunes the accuracy over time). The processing module 50 controls the MMW frequency adjust 358 in accordance with the determination such that the PA 356 generates the desired transmitted MMW signal 364. The LNA 360 amplifies the reflected MMW signal 366 and the mixer 362 down converts the signal such that the processing module 50 receives and processes the signal.
The receive sequence 370 provides the reflection signals in the same order of the transmit sequence 368 with small differences in time (e.g., at r1, r2, r3, . . . ) and frequency. The processing module 50 determines distance information based on the small differences in time and frequency between the receive sequence 370 and the originally transmitted sequence 368.
The bio-medical unit 10 includes the communication module 48 (e.g., for external communications with the communication device and for communications with other bio-medical units), the MEMS propulsion 348, the processing module 50, the memory 52, the power harvesting module 46, a MMW frequency adjust 358, a mixer 362, a low noise amplifier 360 (LNA), and a power amplifier 356 (PA). The bio-medical unit 10 may communicate with other bio-medical units 10 and/or with a communication device 24 to communicate status information and/or commands. For example, the bio-medical unit 10 may coordinate with at least one other bio-medical unit 10 to provide the ultrasound signal 372.
The bio-medical unit 10 may send a transmitted MMW signal 364 to the body object and receive a reflected MMW signal 366 from the body object. Some of the transmitted MMW signal energy is absorbed by the body object, reflected in other directions, and/or transmitted to other directions. Note that the reflections may vary as a function of the ultrasound signal where the reflected signals vary according to the density of the body object.
The bio-medical unit 10 forms a Doppler radar sequence by varying the frequency of the transmitted MMW signal 364 over a series of transmission steps. The bio-medical unit 10 may determine the distance and density based on the reflected MMW signal 366 in response to the Doppler radar.
The bio-medical unit 10 may receive a command from the communication device 24 to reposition, adjust the MMW frequency, and transmit MMW signals 364 to perform the Doppler radar function. In another embodiment, the communication device 24 may send a command to a plurality of bio-medical units 10 to coordinate the formation of a beam to better pinpoint the body object 268 and determine the density. In yet another embodiment, the communication device 24 may send a command to a plurality of bio-medical units 10 to coordinate the Doppler radar function from two, three or more bio-medical units 10 to triangulate the body object 268 location based on the distance information.
The processing module 50 may control the MEMS propulsion 348 to reposition the bio-medical unit 10. The processing module 50 may determine how to control the MMW frequency adjust 358 to affect the distance and density information detection based on a command, a predetermination, and/or an adaptive algorithm (e.g., that detects course distance ranges at first and fine tunes the accuracy over time). The processing module 50 controls the MMW frequency adjust 358 in accordance with the determination such that the PA 356 generates the desired transmitted MMW signal 364. The LNA 360 amplifies the reflected MMW signal 366 and the mixer 362 down converts the signal such that the processing module 50 receives and processes the signal.
As may be used herein, the terms “substantially” and “approximately” provides an industry-accepted tolerance for its corresponding term and/or relativity between items. Such an industry-accepted tolerance ranges from less than one percent to fifty percent and corresponds to, but is not limited to, component values, integrated circuit process variations, temperature variations, rise and fall times, and/or thermal noise. Such relativity between items ranges from a difference of a few percent to magnitude differences. As may also be used herein, the term(s) “operably coupled to”, “coupled to”, and/or “coupling” includes direct coupling between items and/or indirect coupling between items via an intervening item (e.g., an item includes, but is not limited to, a component, an element, a circuit, and/or a module) where, for indirect coupling, the intervening item does not modify the information of a signal but may adjust its current level, voltage level, and/or power level. As may further be used herein, inferred coupling (i.e., where one element is coupled to another element by inference) includes direct and indirect coupling between two items in the same manner as “coupled to”. As may even further be used herein, the term “operable to” or “operably coupled to” indicates that an item includes one or more of power connections, input(s), output(s), etc., to perform, when activated, one or more its corresponding functions and may further include inferred coupling to one or more other items. As may still further be used herein, the term “associated with”, includes direct and/or indirect coupling of separate items and/or one item being embedded within another item. As may be used herein, the term “compares favorably”, indicates that a comparison between two or more items, signals, etc., provides a desired relationship. For example, when the desired relationship is that signal 1 has a greater magnitude than signal 2, a favorable comparison may be achieved when the magnitude of signal 1 is greater than that of signal 2 or when the magnitude of signal 2 is less than that of signal 1.
The present invention has also been described above with the aid of method steps illustrating the performance of specified functions and relationships thereof. The boundaries and sequence of these functional building blocks and method steps have been arbitrarily defined herein for convenience of description. Alternate boundaries and sequences can be defined so long as the specified functions and relationships are appropriately performed. Any such alternate boundaries or sequences are thus within the scope and spirit of the claimed invention.
The present invention has been described, at least in part, in terms of one or more embodiments. An embodiment of the present invention is used herein to illustrate the present invention, an aspect thereof, a feature thereof, a concept thereof, and/or an example thereof. A physical embodiment of an apparatus, an article of manufacture, a machine, and/or of a process that embodies the present invention may include one or more of the aspects, features, concepts, examples, etc. described with reference to one or more of the embodiments discussed herein.
The present invention has been described above with the aid of functional building blocks illustrating the performance of certain significant functions. The boundaries of these functional building blocks have been arbitrarily defined for convenience of description. Alternate boundaries could be defined as long as the certain significant functions are appropriately performed. Similarly, flow diagram blocks may also have been arbitrarily defined herein to illustrate certain significant functionality. To the extent used, the flow diagram block boundaries and sequence could have been defined otherwise and still perform the certain significant functionality. Such alternate definitions of both functional building blocks and flow diagram blocks and sequences are thus within the scope and spirit of the claimed invention. One of average skill in the art will also recognize that the functional building blocks, and other illustrative blocks, modules and components herein, can be implemented as illustrated or by discrete components, application specific integrated circuits, processors executing appropriate software and the like or any combination thereof.
Claims
1. A bio-medical unit comprises:
- a power harvesting module operable to generate a supply voltage from an electromagnetic source signal;
- a first micro-electro mechanical module powered by the supply voltage, wherein the first micro-electro mechanical module transmits a wireless signal; and
- a second micro-electro mechanical module powered by the supply voltage, wherein the second micro-electro mechanical module receives a representation of the wireless signal, wherein the bio-medical unit is of a size for implanting into a host body, wherein, when implanted, the bio-medical unit is positioned proximal to monitor fluid flow in the host body based on the transmitting and receiving of the representation of the wireless signal.
2. The bio-medical unit of claim 1, wherein the bio-medical unit is positioned proximal to monitor fluid flow further comprises:
- positioning the bio-medical unit approximately parallel to blood flow in the host body.
3. The bio-medical unit of claim 1 of claim 1 further comprises:
- a communication module powered by the supply voltage, wherein the communication module is operable to: convert an inbound wireless communication into an inbound symbol stream; convert an outbound symbol stream into an outbound wireless communication;
- a processing module powered by the supply voltage, wherein the processing module is operable to: convert the inbound symbol stream into inbound data; convert outbound data into the outbound symbol stream; generate a control signal based on the inbound data; send the control signal to the first micro-electro mechanical module to enable the first micro-electro mechanical module to transmit the wireless signal; generate flow monitoring data based on the second micro-electro mechanical module receiving the representation of the wireless signal; generate the outbound data based on the flow monitoring data.
4. The bio-medical unit of claim 3, wherein the processing module generating the flow monitoring data further comprises:
- calculating, as the flow monitoring data, a fluid flow rate based on at least one of phase shifting and frequency shifting between the transmitting of the wireless signal and the receiving of the representation of the wireless signal.
5. The bio-medical unit of claim 3, wherein the processing module generating the flow monitoring data further comprises:
- gathering, as the flow monitoring data, at least one of phase shifting data or frequency shifting data based on the transmitting of the wireless signal and the receiving of the representation of the wireless signal.
6. The bio-medical unit of claim 1, wherein the wireless signal comprises at least one of:
- an ultrasound signal;
- a radio frequency signal; and
- a millimeter wave signal.
7. A bio-medical unit comprises:
- a power harvesting module operable to generate a supply voltage from an electromagnetic source signal;
- a first micro-electro mechanical module powered by the supply voltage, wherein the first micro-electro mechanical module transmits a wireless signal; and
- a second micro-electro mechanical module powered by the supply voltage, wherein the second micro-electro mechanical module receives a representation of the wireless signal, wherein the bio-medical unit is of a size for implanting into a host body, wherein, when implanted, the bio-medical unit is positioned proximal to obtain an image of a body object in the host body based on the transmitting and receiving of the representation of the wireless signal.
8. The bio-medical unit of claim 7 further comprises:
- a communication module powered by the supply voltage, wherein the communication module is operable to: convert an inbound wireless communication into an inbound symbol stream; convert an outbound symbol stream into an outbound wireless communication;
- a processing module powered by the supply voltage, wherein the processing module is operable to: convert the inbound symbol stream into inbound data; convert outbound data into the outbound symbol stream; generate a control signal based on the inbound data; send the control signal to the first micro-electro mechanical module to enable the first micro-electro mechanical module to transmit the wireless signal; generate imaging data based on the second micro-electro mechanical module receiving the representation of the wireless signal; generate the outbound data based on the imaging data.
9. The bio-medical unit of claim 8, wherein the processing module generating the flow monitoring data further comprises:
- calculating, as the image data, an image of the body object based on at least one of absorption of the wireless signal by the body object and vibration of the body object.
10. The bio-medical unit of claim 8, wherein the processing module generating the flow monitoring data further comprises:
- gathering, as the image data, at least one of absorption of the wireless signal by the body object and vibration of the body object.
11. The bio-medical unit of claim 7, wherein the wireless signal comprises at least one of:
- an ultrasound signal;
- a radio frequency signal; and
- a millimeter wave signal.
12. A bio-medical unit comprises:
- a power harvesting module operable to generate a supply voltage from an electromagnetic source signal; and
- a micro-electro mechanical module powered by the supply voltage, wherein the second micro-electro mechanical module receives a representation of a wireless signal, wherein the bio-medical unit is of a size for implanting into a host body, wherein, when implanted, the bio-medical unit is positioned proximal to obtain an image of a body object in the host body based on the receiving of the representation of the wireless signal or to monitor fluid flow in the host body based on the receiving of the wireless signal.
13. The bio-medical unit of claim 12 further comprises:
- a communication module powered by the supply voltage, wherein the communication module is operable to: convert an inbound wireless communication into an inbound symbol stream; convert an outbound symbol stream into an outbound wireless communication;
- a processing module powered by the supply voltage, wherein the processing module is operable to: convert the inbound symbol stream into inbound data; convert outbound data into the outbound symbol stream; generate at least one of: imaging data based on the micro-electro mechanical module receiving the representation of the wireless signal; flow monitoring data based on the micro-electro mechanical module receiving the wireless signal; and generate the outbound data based on the imaging data or the flow monitoring data.
14. The bio-medical unit of claim 13, wherein the processing module generating the flow monitoring data further comprises:
- calculating, as the image data, an image of the body object based on at least one of absorption of the wireless signal by the body object and vibration of the body object.
15. The bio-medical unit of claim 13, wherein the processing module generating the flow monitoring data further comprises:
- gathering, as the image data, at least one of absorption of the wireless signal by the body object and vibration of the body object.
16. The bio-medical unit of claim 13, wherein the processing module generating the flow monitoring data further comprises:
- calculating, as the flow monitoring data, a fluid flow rate based on at least one of phase shifting and frequency shifting between the transmitting of the wireless signal and the receiving of the representation of the wireless signal.
17. The bio-medical unit of claim 13, wherein the processing module generating the flow monitoring data further comprises:
- gathering, as the flow monitoring data, at least one of phase shifting data or frequency shifting data based on the transmitting of the wireless signal and the receiving of the representation of the wireless signal.
18. The bio-medical unit of claim 12, wherein the wireless signal comprises at least one of:
- an ultrasound signal;
- a radio frequency signal; and
- a millimeter wave signal.
19. A bio-medical unit comprises:
- a power harvesting module operable to generate a supply voltage from an electromagnetic source signal; and
- a first micro-electro mechanical module powered by the supply voltage, wherein the first micro-electro mechanical module transmits a wireless signal, wherein the bio-medical unit is of a size for implanting into a host body, wherein, when implanted, the bio-medical unit is positioned to transmit the wireless signal at a body object in the host body to obtain imaging data of the body object or to transmit the wireless signal for monitoring fluid flow in the host body.
20. The bio-medical unit of claim 19 further comprises:
- a communication module powered by the supply voltage, wherein the communication module is operable to: convert an inbound wireless communication into an inbound symbol stream; convert an outbound symbol stream into an outbound wireless communication;
- a processing module powered by the supply voltage, wherein the processing module is operable to: convert the inbound symbol stream into inbound data; convert outbound data into the outbound symbol stream; generate a control signal based on the inbound data; and send the control signal to the micro-electro mechanical module to enable the micro-electro mechanical module to transmit the wireless signal.
21. The bio-medical unit of claim 19, wherein the wireless signal comprises at least one of:
- an ultrasound signal;
- a radio frequency signal; and
- a millimeter wave signal.
Type: Application
Filed: Jul 1, 2010
Publication Date: Mar 31, 2011
Applicant: BROADCOM CORPORATION (Irvine, CA)
Inventor: Ahmadreza (Reza) Rofougaran (Newport Coast, CA)
Application Number: 12/829,299
International Classification: A61B 5/07 (20060101); A61B 1/04 (20060101);