FIELD OF THE INVENTION The present invention is in the field of bladder cancer diagnosis, and in particular the methods for predicting the progression of bladder cancer tumors. The invention provides diagnostic methods and diagnostic compositions for use in such methods. The invention further provides therapeutic targets for treating specific forms of bladder cancers.
BACKGROUND OF THE INVENTION Bladder cancer is the fifth most common cancer in the western world with an incidence of 20 new cases per year per 100,000 people in the U.S. Unfortunately, these statistics do not include superficial pTa bladder cancer, which represents the most common type of bladder cancer. In the Netherlands, the incidence of both superficial and invasive bladder cancer is estimated as about 30 new cases per year per 100,000 people. This is in accordance with data from global cancer statistics for the western world. Superficial bladder tumors are removed by transurethral resection. However, up to 70% of these patients will develop one or more recurrences, and it has been estimated that 1 in 1,450 people is under surveillance for bladder cancer in the United Kingdom. Cystoscopy is an uncomfortable, invasive, and expensive procedure, but currently remains the gold standard for detection of recurrences. Because patients have to be monitored perpetually and have a long-term survival, bladder cancer is the most expensive cancer when calculated on a per patient basis.
Hence there exists a need for an inexpensive, noninvasive, and simple procedure for the detection of bladder cancer. Cytology done on voided urine is a noninvasive procedure with up to 100% specificity. Unfortunately, this method is limited by its sensitivity, which is especially poor for low-grade tumors. Because of this limited sensitivity, alternative methods need to be developed for the detection of tumor cells in voided urine.
SUMMARY OF THE INVENTION The present inventors have found that the methylation of a number of specific CpG islands (CGIs) in the DNA of cells shaded in the urine of a subject is indicative of the present of a tumor, in particular a bladder tumor. Thus, aberrant methylation of these CpG islands in the DNA of a subject may be used as diagnostic and/or prognostic marker as well as a therapeutic target.
The present finding has been found to be particularly advantageous in the case of bladder cancer diagnostics (including disease prognosis and prediction of disease recurrence and progression), since the detection of methylation may occur in DNA (of cells) in a sample of urine obtained from the subject to be diagnosed. In particular urothelial cells present in said urine sample are used for this purpose. The skilled person will understand that diagnostic methods as indicated herein may make use of any body sample in which DNA comprising the aberrant methylations as defined herein can be detected, including biopsies of cancerous tissue, or tissue suspected of being malignant.
The present inventors have demonstrated the suitability of using methylation of specified CpG islands as diagnostic markers in bladder cancer diagnostics, such as for:
-
- detection of recurrent cancer in DNA isolated from patient urine, and
- detection of primary cancer in DNA isolated from patient urine.
Thus, in a first aspect, the present invention provides a method for diagnosing cancer in a subject comprising detecting in the DNA of said subject at least one hypermethylated CpG island associated with said cancer, wherein an elevation in the level of methylation in said CpG island of said subject, relative to the level of methylation in said CpG island of a control subject, is indicative of said CpG island being hypermethylated. The presence of a hypermethylated CpG island might indicate that the subject is at risk of, or suffering from, a cancer.
Preferably said CpG island is selected from the group consisting of the CpG islands listed in Table 1, Table 2, Table 3, Table 4, Table 5, Table 7, Table 9, Table 10 and Table 12.
In a preferred embodiment of methods of the invention, said cancer is bladder cancer.
In another preferred embodiment of methods of the invention, said method comprises detection of recurrent forms of cancer in DNA isolated from patient urine and wherein said at least one CpG islands methylation associated with cancer selected from the group consisting of the CpG islands listed in Table 1, Table 2, Table 3, Table 4, Table 5, Table 7, Table 9, Table 10 and Table 12.
In yet another preferred embodiment of methods of the invention, said method comprises detection of primary forms of cancer in DNA isolated from patient urine and wherein said at least one CpG islands methylation associated with cancer selected from the group consisting of the CpG islands listed in Table 1, Table 2, Table 3, Table 4, Table 5, Table 7, Table 9, Table 10 and Table 12.
In still a further preferred embodiment of methods of the invention, said DNA is obtained from a urine sample of said subject.
In another preferred embodiment of methods of the invention, said bladder cancer is non muscle-invasive bladder cancer. Alternatively, said bladder cancer is muscle-invasive bladder cancer. In a further preferred embodiment, said method provides detection of differential methylation of one or more of the genes provided in Table 7. Differential methylation of one or more of the genes provided in Table 7 is used to discriminate between subgroups of bladder cancer, such as between NMI-wt and MI and NMI-mt groups.
In a preferred embodiment of methods of the inveniton, general inflammatory cells in urine, preferably lymphocytes, are detected by methylation of at least one of the CGIs listed in Table 9. Table 9 indicates a number of CGIs methylated in blood but not in bladder cancer. The differential methylation of these CGIs, which can be detected in DNA (of cells) in a sample of urine obtained from the subject to be diagnosed, and in particular in urothelial cells present in said urine sample, are useful for the detection of lymphocytes in urine, or in general inflammatory cells in urine, which is indicative of cystitis. Positive detection of the presence of inflammatory cells in the urine can be used to diagnose infection or non-infective inflammation of the urinary tract and kidney.
In a preferred embodiment, said method comprises detection of recurrent cancer in DNA isolated from patient urine. This method entails the detection of specific CpG island methylations associated with recurrent forms of the cancer.
In another preferred embodiment, said method comprises detection of primary cancer in DNA isolated from patient urine. This method entails the detection of specific CpG island methylations associated with primary forms of the cancer.
The present inventors have further demonstrated the suitability of using methylation of specified CpG islands as prognostic markers in bladder cancer diagnostics, such as for:
-
- prediction of disease course based on analysis of tumor-derived or urine derived DNA, including:
- prediction of invasive potential of non-muscle invasive urothelial carcinomas;
- prediction of urothelial carcinoma-specific survival, and
- prediction of presence/absence of lymph node and distant metastases caused by urothelial carcinomas
Thus, in a second aspect, the present invention provides a method for the prediction of the recurrence, progression or prognosis of cancer, in particular bladder cancer, comprising detecting in the DNA of said subject at least one hypermethylated CpG island associated with said cancer, wherein an elevation in the level of methylation in said CpG island of said subject, relative to the level of methylation in said CpG island of a control subject, is indicative of said CpG island being hypermethylated. The presence of a hypermethylated CpG island might indicate that the subject is at risk of cancer recurrence, progression of a cancer, and/or poor prognosis. A preferred method for the prognosis of a risk of cancer recurrence, progression of a cancer, and/or poor prognosis comprises detection of one or more methylated CpGs in CGIs of the genes listed in Table 12B, whereby the CGIs are preferably chosen from GPR103, DBC1 and/or GATA2 genes. Said cancer is preferably bladder cancer.
In a preferred embodiment of said method for the prediction of the recurrence, progression or prognosis of cancer, said CpG island is selected from the group consisting of the CpG islands listed in Table 1, Table 2, Table 3, Table 4, Table 5, Table 7, Table 9, Table 10 and Table 12, preferably from Table 5 and Table 10.
In aspects of the present invention the methylation of dinucleotide in or methylation level of a CpG island may be determined by any method available to the skilled person. Preferably said method comprises methylation-specific PCR (MSP). Alternatively, or additionally, use may be made of a multiplex ligation-dependent probe amplification (MLPA).
The present inventors have further demonstrated the suitability of using methylation of specified CpG islands as markers in bladder cancer diagnostics for prediction of therapeutic response, such as for prediction of failure or success of (neo)-adjuvant therapies.
The present inventors now envision as part of their invention the use of demethylating agents capable of specifically demethylating the CpG islands associated with tumor, in particular bladder cancer, as defined herein. They may also be of use as priming therapy for chemotherapeutic regimes.
Hence, the present invention provides a method for the treatment or prevention of cancer, in particular bladder cancer, comprising administering to a subject in need of such treatment a therapeutically effective amount of a demethylating agent capable of selectively demethylating at least one of the CpG islands methylations associated with cancer as described herein.
Clinical outcome of demethylating agents may depend on specific methylation profiles.
The present invention further provides pharmaceutical compositions comprising demethylating agents capable of selectively demethylating at least one of the CpG islands methylations associated with cancer as described herein.
The present invention further provides diagnostic compositions comprising PCR primirs and reagent or probes capable of selectively hybridising under stringent conditions to hypermethylated CpG islands as defined herein.
DETAILED DESCRIPTION OF THE INVENTION As used herein the term “CpG island” refers to genomic regions that contain a high frequency of CG nucleotides. In mammalian genomes, CpG islands are typically 300-3,000 base pairs in length. They are in and near approximately 40% of promoters of mammalian genes (about 70% in human promoters). The “p” in CpG notation refers to the phosphodiester bond between the cytosine and the guanine. CpG islands are characterized by CpG dinucleotide content of at least 60% of that which would be statistically expected (˜4-6%), whereas the rest of the genome has much lower CpG frequency (˜1%), a phenomenon called CG suppression. Unlike CpG sites in the coding region of a gene, in most instances, the CpG sites in the CpG islands of promoters are unmethylated if genes are expressed.
As used herein the term “CpG island methylation” refers to a methylation of at least one CG dinucleotide in a CpG region as defined herein. Hence, the methods of the present invention include the detection of at least a single CG dinucleotide being methylated in a CpG island as defined herein.
As used herein the term “hypermethylated CpG islands” refers to a CpG island exhibiting an elevation in the level of methylation, relative to the level of methylation in the same CpG island of a control subject. Again, the level of methylation includes the presence of a single methylated CG dinucleotide in the CpG island as compared to the control situation, in which the same CpG island is unmethylated. Also, methods of the invention include embodiments wherein the methylation of a single CG dinucleotide in a CpG island as defined herein is detected among other methylated sites.
As used herein, “cancer” shall be taken to mean any one or more of a wide range of benign or malignant tumors, including those that are capable of invasive growth and metastasis through a human or animal body or a part thereof, such as, for example, via the lymphatic system and/or the blood stream. As used herein, the term “tumor” includes both benign and malignant tumors or solid growths, notwithstanding that the present invention is particularly directed to the diagnosis or detection of malignant tumors and solid cancers. Typical cancers include but are not limited to carcinomas, lymphomas, or sarcomas, such as, for example, ovarian cancer, colon cancer, breast cancer, pancreatic cancer, lung cancer, prostate cancer, urinary tract cancer, uterine cancer, acute lymphatic leukemia, Hodgkin's disease, small cell carcinoma of the lung, melanoma, neuroblastoma, glioma, and soft tissue sarcoma of humans; and lymphoma, melanoma, sarcoma, and adenocarcinoma of animals.
The term “bladder cancer” as used herein refers in general to urothelial cell carcinoma, i.e. carcinomas of the urinary bladder, ureter, renal pelvis and urethra. The term includes reference to the non muscle-invasive (NMI) or superficial forms, as well as to the more dangerous muscle invasive (MI) types. Also included in the term is reference to the primary forms as well as to recurrent forms of the cancer.
The NMI types may further be subdivided into FGFR3+ and FGFR3−. Mutations in the fibroblast growth factor receptor 3 (FGFR3, indicated herein as FGFR3+) occur in 50% of primary bladder tumors. It is known (e.g. Van Oers et al. 2005 Clin. Cancer Res; 11(21), pp. 7743-7748) that an FGFR3 mutation is associated with good prognosis, illustrated by a significantly lower percentage of patients with progression and disease-specific mortality. FGFR3 mutations are especially prevalent in low grade/stage tumors, with pTa tumors harboring mutations in 85% of the cases. These tumors recur in 70% of patients. Efficient FGFR3 mutation detection for prognostic purposes and for detection of recurrences in urine is an important clinical issue. Thus, in preferred embodiments of the present invention the method of diagnosis includes further the step of detecting an FGRF3 gene mutation. This additional step may be performed prior to, during or after the step of detecting the hypermethylated CpG island as indicated herein. The detection of the FGFR3 gene mutation as indicated in Van Oers et al (this reference is expressly referred to and incorporated herein by reference in its entirety for the methods and mutations to be detected as described therein) indicates the cancer is very likely of the non invasive type.
“Subject” as used herein includes, but is not limited to, mammals, including, e.g., a human, a non-human primate, a mouse, a pig, a cow, a goat, a cat, a rabbit, a rat, a guinea pig, a hamster, a degu, a horse, a monkey, a sheep, or other non-human mammal; and non-mammal animals, including, e.g., a non-mammalian vertebrate, such as a bird (e.g., a chicken or duck) or a fish, and an invertebrate.
A method of the invention can be performed on any suitable body fluid, such as for instance on abdominal fluid, pleural fluid, bronchial fluid, pericardial fluid, blood, serum, milk, plasma, sweat, tears, urine, peritoneal fluid, lymph, vaginal secretion, semen, spinal fluid, cerebrospinal fluid, ascitic fluid, saliva, stool, sputum, mucus or breast exudate. Preferably, a method of the invention is performed on blood, serum, plasma or ascitic fluid, more preferably serum. Depending on the methods employed, the skilled person will be capable of establishing the amount of sample required to perform the various steps of the method of the present invention. Generally, such amounts will comprise a volume ranging from 0.01 μl to 100 ml or more. Preferred samples are urine samples.
In even more preferred embodiments of aspects of the invention the cell fraction of urine, preferably tumor cell fraction, is used. Urine cell fractions may be obtained by filtration or centrifugation. The cellular DNA may subsequently be analyzed, for instance upon extraction of the DNA from the cells, although in situ methods performed on whole cells are also envisioned.
The skilled physician or biologist will be familiar with the various ways of providing a sample of a body fluid from a subject, in particular an urine sample. Urine collection and preparation of the sample for CpG island methylation analysis suitably comprises for instance the collection of a urine sample were collected into a 50 ml centrifuge tube. The sample may optionally be used for additional tests, such as dip stick tests for leucocytes, erythrocytes and nitrite as routinely performed in the art. The cells in the urine are suitably spun down for 10 min @ 3000 rpm; 4° C. An amount of supernatant is suitably stored at −80° C. for later use. The cell pellet may then be washed, for instance by adding a suitable amount of PBS (phosphate-buffered saline), such as 10 ml, to the cell pellet. After mixing and centrifugation (e.g. 10 min @ 3000 rpm; 4° C.), the PBS may be discarded. The cell pellet may then be resuspended in PBS (e.g. 1 ml) and transferred to a microcentrifuge tube. The suspension is then suitably centrifuged (e.g. 5 min @ 6000 rpm; 4° C.). The supernatant can then be carefully removed and the cell pellet may be stored in a −80° C. freezer until DNA extraction.
Commercial systems for DNA isolation from blood, urine and tissue are available form various suppliers of molecular biological reagents. Special reference is made to the DNeasy® Blood & Tissue Kit and DNeasy® 96 Blood & Tissue Kit available from QIAGEN GmbH, Hilden, Germany.
The term “therapeutically effective amount” as used herein refers to an amount of a therapeutic agent to treat, ameliorate, or prevent a desired disease or condition, or to exhibit a detectable therapeutic or preventative effect. The effect can be detected by, for example, chemical markers or antigen levels. Therapeutic effects also include reduction in physical symptoms. The precise effective amount for a subject will depend upon the subject's size and health, the nature and extent of the condition, and the therapeutics or combination of therapeutics selected for administration. Thus, it is not useful to specify an exact effective amount in advance. However, the effective amount for a given situation can be determined by routine experimentation and is within the judgment of the clinician.
For purposes of the present invention, an effective dose will be from about 0.01 mg/kg to 50 mg/kg or 0.05 mg/kg to about 10 mg/kg of the polynucleotide or polypeptide compositions in the individual to which it is administered.
The present invention also pertains to pharmaceutical compositions comprising demethylating agents as defined herein.
A pharmaceutical composition can also contain a pharmaceutically acceptable carrier. The term “pharmaceutically acceptable carrier” refers to a carrier for administration of a therapeutic agent, such as a polypeptide, polynucleotide, and other therapeutic agents. The term refers to any pharmaceutical carrier that does not itself induce the production of antibodies harmful to the individual receiving the composition, and which may be administered without undue toxicity. Suitable carriers may be large, slowly metabolized macromolecules such as proteins, polysaccharides, polylactic acids, polyglycolic acids, polymeric amino acids, amino acid copolymers, and inactive virus particles. Such carriers are well known to those of ordinary skill in the art.
Pharmaceutically acceptable salts can be used therein, for example, mineral acid salts such as hydrochlorides, hydrobromides, phosphates, sulfates, and the like; and the salts of organic acids such as acetates, propionates, malonates, benzoates, and the like. A thorough discussion of pharmaceutically acceptable excipients is available in Remington's Pharmaceutical Sciences (Mack Pub. Co., N.J. 1991).
Pharmaceutically acceptable carriers in therapeutic compositions may contain liquids such as water, saline, glycerol and ethanol. Additionally, auxiliary substances, such as wetting or emulsifying agents, pH buffering substances, and the like, may be present in such vehicles. Typically, the therapeutic compositions are prepared as injectables, either as liquid solutions or suspensions; solid forms suitable for solution in, or suspension in, liquid vehicles prior to injection may also be prepared. Liposomes are included within the definition of a pharmaceutically acceptable carrier.
Once formulated, the pharmaceutical compositions of the invention can be (1) administered directly to the subject; (2) delivered ex vivo, to cells derived from the subject; or (3) delivered in vitro for expression of recombinant proteins.
Direct delivery of the compositions will generally be accomplished by injection, either subcutaneously, intraperitoneally, intravenously or intramuscularly, or delivered to the interstitial space of a tissue. The compositions can also be administered into the nervous system. Other modes of administration include topical, oral, suppositories, and transdermal applications, needles, and particle guns or hyposprays. Dosage treatment may be a single dose schedule or a multiple dose schedule.
Specific aspects of the present invention relate to the CpG islands indicative of certain forms of cancer emerging for instance from the following comparisons:
A) CpG islands hypermethylated in non muscle-invasive (NMI) bladder cancer (BC) that are FGFR3 wild type, herein referred to as NMI-BC wt, vs. muscle-invasive (MI) bladder cancer herein referred to as MI-BC (n=31)
B) CpG islands hypermethylated in MI-BC vs. NMI-BC wt (n=11)
C) CpG islands hypermethylated in all bladder cancers (n=62)
D) CpG islands hypermethylated in NMI-BC-FGFR3 wild type vs. NMI-BC-FGFR3 mutant (n=31), and
E) Hypermethylated CpG islands predicting progression of disease or death of disease (resp. n=3 and n=11)).
The methods of the invention comprise the detection of hypermethylated CpG islands in the DNA of a subject. As indicated, hypermethylation is a relative term indicating that the methylation level of the respective CpG island is higher than or elevated with respect to the methylation level of the corresponding CpG island in a healthy control subject.
The methods of the invention comprise the detection of at least one hypermethylated CpG island in the DNA of a subject. Since there are many CpG island indicated herein whose hypermethylation is indicative of cancer, in particular bladder cancer, the method preferably entails the detection of at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, or more, such as 35, 40, 45, 50, 55, 60, 65 or more hypermethylations in the DNA of a subject. In such instances, it is possible to speak of a CpG island methylation profile. In such a profile, the percentage of positively dectected CpG islands is preferably at least 50%, more preferably at least 70%, more preferably at least 90%.
The CpG island methylation profiles may comprise of between 2-25 CpG islands for diagnostic purpose, such as determining whether a bladder cancer is present, and/or whether it is an NMI or MI type.
The CpG island methylation profiles preferably comprise of between 2-25, more preferably more, such as between 50 and 150, for instance about 100 CpG islands for diagnostic purpose, such as determining the prognosis of an NMI to develop into a more aggressive MI type of tumor. Thus, the present invention provides for a prognostic method for determining whether an NMI type bladder cancer can develop into an MI type.
It is also possible to use a method of the present invention to distinguish between a primary or recurrent form of the tumor.
The skilled person is well aware of the various methods that have been developed to analyze DNA methylation. Amongst these methods are restriction enzyme- and sodium bisulfite based approaches, as well as multiplex ligation-dependent probe amplification (MLPA) approches.
Restriction-enzyme based methods are based on the inability of methylation sensitive restriction enzymes to cleave methylated cytosines in their recognition site. The identification of the methylation status relies on Southern hybridization techniques or PCR and is based on the length of the digested DNA fragment. The inability to digest methylated sequences results in longer fragments, indicating a methylated CpG dinucleotide. Restriction-enzyme based methods are simple, rapid and highly sensitive and are suitable for genome-wide methylation analyses as well as marker discovery techniques.
Preferred methods for application in aspects of the present invention is sodium bisulfite (NaHSO3) based detection of DNA methylation. Such methods are essentially based on the fact that treatment of single-stranded DNA with sodium bisulfite results in sequence differences due to deamination of unmethylated cytosines to uracil under conditions whereby methylated cytosines remain unchanged. The difference in methylation status marked by bisulfite reactivity can accurately be determined and quantified by PCR-based technology. Bisulfite sequencing techniques (such as described in Frommer et al. Proc. Natl. Acad. Sci. USA 89 (1992), 1827-1831) provide qualitative data on the methylation status of 5-methylcytosines in the amplicon between the sequence primers and thus requires primers specific for bisulfite converted, but not specific for unmethylated or methylated DNA. This approach provides detailed information on the methylation status of all CpG-sites.
A methylation-specific PCR (MSP) assay for determining the methylation status of CpG islands may be used. Such methods are for instance described in Herman et al. 1996 (Proc. Natl. Acad. Sci. USA 93 (1996), 9821-9826) and Herman and Baylin (Current Protocols in Human Genetics 10 (1998), 10.16.11-10.16.10). The MSP assay is based on the use of two distinct methylation-specific primer sets for the sequence of interest. The unmethylated (U) primer only amplifies sodium bisulfite converted DNA in unmethylated condition, while the methylated (M) primer is specific for sodium bisulfite converted methylated DNA. Using MSP, 1 methylated allele may be detected in a background of 1000 unmethylated alleles. MSP is very suitable for analyzing the methylation status of CpG dinucleotides in a CpG-island. The method may also be applied for high-throughput analysis of clinical samples. The most critical parameters determining the success and specificity of MSP, i.e. bisulfite conversion, primer design and PCR as well as several post PCR validation approaches are discussed in Derks et al. 2004 (Cellular Oncology 26 (2004) 291-299). Methylation Specific PCR (MSP) is described in great detail in U.S. Pat. No. 5,786,146, U.S. Pat. No. 6,017,704, U.S. Pat. No. 6,200,756 and U.S. Pat. No. 6,265,171 and International Patent WO 97/46705.
Commercial systems for DNA methylation analysis using MSP are available form various suppliers of molecular biological reagents. Special reference is made to the EZ DNA Methylation-Startup™ Kit and EZ DNA Methylation-Direct™ Kit available from Zymo Research Corp. Orange, Calif., U.S.A.
Use can also be made, alone, or in combination with any of the above, of the MLPA technique. The MLPA technique is for instance described in great detail in Schouten et al., 2002 (Nucleic Acids Research 3(12) e57, 13 pp.).
Also, use can be made of a microarray chip to which DNA of a subject is hybridized. Such arrays for CpG islands are for instance commercially available from Agilent Technologies Inc., Santa Clara, USA.
Herein below are provided the following Tables:
Table 1. Coordinates of selected regions containing relevant CpG islands based on Homo sapiens full genome as provided by UCSC (hg18, March 2006). These CpG islands are aspect of the present invention as hypermethylation of these regions is associated with cancer, preferably bladder cancer and/or certain forms of said cancer.
Table 2. CpG islands differentially methylated in NMI-BC wt vs. invasive BC. These 42 CpG islands are aspect of the present invention as hypermethylation of these regions is associated with either NMI or more aggressive MI forms of the cancer. Hence, these regions are particularly indicated for use in diagnostic methods wherein typing of the cancer is relevant. The table provides data on CpG islands hypermethylated in non muscle-invasive (NMI) bladder cancer (BC) that are FGFR3 wild type, herein referred to as NMI-BC wt, vs. muscle-invasive (MI) bladder cancer herein referred to as MI-BC (n=31) as well as CpG islands hypermethylated in MI-BC vs. NMI-BC wt (n=11).
Table 3. CpG islands hypermethylated in (bladder) cancer. These 62 CpG islands are aspect of the present invention as hypermethylation of these CpG islands is associated with (bladder) cancer.
Table 4. CpG islands hypermethylated in NMI-BC FGFR3 wt vs NMI-BC FGFR3 mut. These 31 CpG islands are aspect of the present invention diagnostic markers for typing of (bladder) cancers and in particular indicate the relevance of FGFR3 mutations in bladder cancer. These 31 CpG islands may be used for diagnosis of FGFR3 wt primary and recurrent tumors in for instance urine. These 31 CpG islands may also be used for detection of FGFR3 wt tumors in patients with a FGFR3 ml (mutant) primary tumor. Alternatively, these 31 CpG islands may be used for the identification of recurrences that progressed to muscle-invasive disease or to stage pT1 or to high grade (WHO 2004 grading system) or G3(WHO grading system 1973). These 31 CpG islands may also be used to present specific targets for therapy in NMI-BC tumors that are FGFR3 wt.
Table 5. CpG islands potentially involved in progression and death of disease. These 14 CpG islands are aspect of the present invention as hypermethylation of these regions is associated with prediction of the recurrence, progression or prognosis of cancer of cancer, in particular bladder cancer.
Table 7 (including Tables 7A and 7B) indicates differentially labeled CGIs between subgroups of bladder cancer and/or between subgroups of bladder cancer and a reference sample (i.e. blood).
Table 9 indicates a number of CGIs methylated in blood but not in bladder cancer. The differential methylation of these CGIs, which can be detected in DNA (of cells) in a sample of urine obtained from the subject to be diagnosed, and in particular in urothelial cells present in said urine sample, are—apart from the purpose indicated herein for diagnosing bladder cancer—also useful for the detection of lymphocytes in urine, or in general inflammatory cells in urine, which is indicative of cystitis. Positive detection of the presence of inflammatory cells in the urine can be used to diagnose infection or non-infective inflammation of the urinary tract and kidney.
Table 10 provides a list of hypermethylated CGIs that show 3 or more CpG dinucleotides highly methylated in a specific CGI. This list comprises 82 CGIs representing 71 genes and 11 CGIs not directly associated with a gene. A preferred gene from Table 10 is MEIS1, showing the highest degree of methylation with a fold change of 4.8 and an average fold change of 2.2 across the 10 probes that were present on the array for this CGI.
Table 12 (including Tables 12A and 12B) provides a list of CGIs that are differentially methylated between tumors and urine from non-bladder cancer control. These genes represent potential biomarkers for urine tests.
LEGEND TO THE FIGURES FIG. 1. Methylation pattern and expression of selected genes. (a) MEIS1, (b) NR4A2 and (c) HOXA9. (d), (e), (f) are Box plots representing the expression profiles which were taken from oncomine
FIG. 2. Comparison of differential methylation between subgroups. (a) Unsupervised analysis performed on all probes present on the 244K array without selection: PCA showing the distinct bladder tumor groups cluster separately (Red-MI, Blue-NMI-mt and Green NMI-wt), (b) Venn diagram showing the number of CGIs that are differentially methylated
FIG. 3. Semi-supervised analyses between bladder tumor subgroups involving hierarchical clustering and PCA. (a) Clustering and PCA of NMI-mt and NMI-wt tumors, (b) Clustering and PCA of MI and NMI-wt tumors, (c) Clustering and PCA of NMI-mt and MI tumors.
FIG. 4. Most methylated gene-associated CGIs are targets of polycomb complexes. (a) Overrepresentation of PcG genes in BC methylated CGIs. (b), Venn diagram showing the overlap in PcG target genes between bladder cancer subgroups.
FIG. 5. A. Hierarchical clustering of GGMA data of all the investigated samples. B. Heat map showing the probes which are methylated in all tumor subgroups vs. blood and urine; C) Methylation of two CpGs in the MEIS1 CGI (black peaks: methylated CpG, red: not methylated. IM, in vitro methylated DNA; RT112, T24, J82: bladder cancer cell lines; PU: patient urine; NU: normal urine; NB: blood), D) KM curve for progression to muscle-invasive disease based on a combination of methylation of GRP103, DBC1 and GATA2.
TABLE 1
Coordinates of selected regions containing relevant
CpG islands based on Homo sapiens full genome as provided by UCSC
(hg18, March 2006)
chr1: 119333484-119333719 chr1: 149638545-149639227 chr1: 160220156-160220709
chr1: 178464743-178471598 chr1: 2072175-2072389 chr1: 2106293-2106715
chr1: 232106869-232108183 chr1: 33385564-33385979 chr1: 41122328-41122880
chr1: 47672249-47672972 chr1: 68288825-68289104 chr1: 71284766-71286392
chr10: 21828640-21829645 chr10: 22804715-22807056 chr10: 73437163-73438385
chr10: 7449476-7449790 chr10: 7489383-7495345 chr12: 113657930-113659205
chr12: 118612357-118612674 chr12: 94776044-94776377 chr13: 113930978-113931584
chr13: 34950488-34951119 chr13: 49595986-49600287 chr13: 94152191-94153185
chr14: 36205192-36206099 chr14: 37746906-37747538 chr14: 53488428-53488700
chr15: 94688798-94689131 chr15: 94696311-94696840 chr15: 94705727-94706054
chr15: 94712480-94712812 chr16: 52873104-52882105 chr16: 52873104-52882105
chr16: 85098883-85102729 chr16: 86294154-86294408 chr16: 87372445-87372729
chr17: 24303411-24303889 chr17: 34157398-34159854 chr17: 44074280-44075233
chr17: 56827843-56838048 chr17: 58865328-58865618 chr17: 73932992-73933361
chr17: 75377960-75381951 chr17: 75531280-75531546 chr18: 5186244-5187389
chr18: 68359955-68362770 chr19: 4059891-4060207 chr19: 42586165-42586705
chr19: 63420090-63420541 chr19: 63784504-63785085 chr2: 104835284-104839920
chr2: 105864220-105865009 chr2: 111591678-111597436 chr2: 115635091-115637285
chr2: 124498611-124499725 chr2: 156892636-156892878 chr2: 156893736-156894685
chr2: 171384729-171385226 chr2: 176737610-176738187 chr2: 19424445-19425131
chr2: 43251514-43251780 chr2: 45249374-45251726 chr2: 63134470-63134933
chr2: 66525936-66527222 chr2: 70984709-70985764 chr2: 72224630-72228512
chr20: 22505518-22507240 chr20: 22510737-22514165 chr20: 22514762-22515148
chr20: 35582018-35583550 chr20: 54012011-54014085 chr20: 60061693-60062033
chr21: 33316999-33322115 chr21: 36990008-36995832 chr21: 37857725-37858416
chr21: 43350621-43351134 chr3: 129688131-129694023 chr3: 148591199-148594390
chr3: 62330280-62330608 chr3: 62331767-62332398 chr4: 111780013-111780343
chr4: 122520930-122521740 chr4: 155881084-155881434 chr4: 177159356-177159814
chr4: 40134579-40135662 chr4: 9756136-9756429 chr5: 115810975-115811393
chr5: 122461778-122463450 chr5: 134390896-134393045 chr5: 135442969-135443206
chr5: 140724146-140724826 chr5: 174091287-174092335 chr6: 101023927-101024343
chr6: 1549606-1560865 chr6: 21704622-21705099 chr6: 26312699-26313302
chr7: 121727243-121727884 chr7: 1481682-1482268 chr7: 155266364-155266696
chr7: 155288454-155292175 chr7: 156895132-156895886 chr7: 2082782-2083345
chr7: 27164708-27165039 chr7: 27219187-27220360 chr7: 2724511-2724848
chr7: 27251165-27252762 chr7: 32768010-32768497 chr7: 55040457-55041024
chr7: 8449587-8450236 chr7: 96488158-96489591 chr8: 132985505-132986242
chr8: 142288380-142288718 chr8: 57520625-57522095 chr8: 65661156-65662687
chr8: 9798161-9799053 chr9: 121170908-121172141 chrX: 39749470-39754050
chrX: 50040955-50041296
TABLE 2
CpG islands differentially methylated in NMI-BC wt vs
invasive BC. Provided for each are: ID; Comparision; Coordinates of selected
regions containing relevant CpG islands based on Homo sapiens full genome
as provided by UCSC (hg18, March 2006); Chromosome; GeneName; Location
relative to gene Sequence.
7; I vs SW; chr1: 41122328-41122880; 1; chr1: 041122606-041122650; Unknown
CGGATGTGCGTGGACTCTGCGGGCGGGGCGCCCGTAGTCTCCCTCCTTCGCACCCCGGGCGCCTGGGAAC
CTCCTCGCGCGTTTGGCCACTCGCTGCTCCTGGCAGTAGGGGCTTCGGGCCCCGCCGTGTCCCCACCCAG
GTATGGGGATGCGGAGTTGATGGGTGCGGGGCGCTGGGAGGGGGCAGATGAAAGGGGCAGTCGAAAGG
GGGCCATGCGCGCCGAGCGCAGCCGGGTCATTAGCCGCGGGTGTGAGCGGCGGGGCAGGCTTATCGCCC
ATCCAGGCCTGGCGGGCGGGCGGTCCCCGACGCGGCTGCCGCCGCCGCCCGCGGCAGAGGGCACGGCGG
TTCCCACGCTCGGGCCCTGGTTCGGGGGCGTTCTCGGGACGGCGTGGCCGCGCTCACCACCACCGCGGA
GGCCGGGCTGTAATTAGGATAATTGCGCTGCTCCCAGCCTGGGGCAGCTCAGGACCCGGCTGCACCGCGC
TGGCCCGGGACGGGCGGGGGCAGGGGGTGGCGGGGCCCGAGCGATACAGCCCCTGGCGCAGTCCG
61; I vs SW; chr10: 73437163-73438385; 10; CHST3; INSIDE
CGCCCAGACCGGCCGTGGCGGGGCCCCGGCGCCACGTGCTGCTCATGGCCACCACGCGCACCGGCTCCT
CGTTCGTGGGCGAGTTCTTCAACCAGCAGGGCAACATCTTCTACCTCTTCGAGCCGCTTGGCACATCGAGC
GCACAGTGTCCTTCGAGCCGGGGGGCGCCAACGCCGCGGGCTCGGCCCTGGTGTACCGCGACGTGCTCA
AGCAGCTCTTCCTGTGCGACCTGTACGTGCTGGAGCACTTCATCACGCCGCTGCCCGAGGACCACCTGAC
TCAGTTCATGTTCCGCCGGGCTCCAGCCGCTCCCTGTGCGAGGACCCCGTCTGTACGCCCTTCGTCAAGA
AGGTCTTCGAGAAGTACCACTGCAAGAACCGCCGCTGCGGCCCCCTCAACGTGACGCTGGCCGCAGAGGC
CTGCCGCCGCAAGGAGCACATGGCCCTCAAGGCGGTGCGCATCCGGCAGCTGAGTTCCTGCAGCCGCTGG
CCGAGGACCCCCGCCTGGACCTGCGCGTCATCCAGCTGGTGCGCGACCCCCGGGCCGTGCTGGCCTCGC
GCATGGTGGCCTTCGCCGGCAAGTATAAGACCTGGAAGAAGTGGCTGGACGACGAGGGCCAGGACGGCC
TGAGGGAAGAGGAGGTCAGCGGCTGCGGGGCAACTGCGAGAGCATCCGCCTGTCCGCGGAGCTGGGGCT
GCGGCAGCCCGCCTGGCTGCGGGGCCGCTACATGCTGGTGCGCTACGAGGACGTGGCACGCGGGCCGCT
GCAGAAGGCCCGCGAGATGTACCGCTTCGCCGGCATCCCCCTGACCCCGCGGTGGAAGACTGGATCCAAA
AGAACACGCAGGCGGCCCACGACGGCAGCGGCATCTACTCCACGCAGAAGAACTCCTCGGAGCAGTTCGA
GAAGTGGCGCTTCAGCATGCCCTTCAAGCTGGCCCAGGTGGTGCAGGCCGCCTGCGGCCCTGCCATGCGC
CTCTTCGGCTACAACTGGCGCGGGACGCCGCCGCCCTCACCAACCGCTCAGTCAGCCTGCTGGAGGAGAG
GGGCACCTTCTGGGTCACGTAGGGGGGCCGGGGCCCCGTATGCCCCTCCTCGTGAAAGGCCTGCCCCGTC
TTTCTGCCGCAGCCCTCGCAGAGGGCGGGTGCACAGCGCCATGACGGGCAGCGCCTCCTGTAGCAGTAGG
GCCCCCAGCCAGCGCTCCAGCCAA
97; I vs SW; chr12: 118612357-118612674; 12; CIT; INSIDE
CGGGGTCCTCACGGCTCCCGCAGGCAGCCGGCCCCTGCTGCTGTCTTCAAACAGCCTCCCGGGGGACCGC
TCTCTCCGCGTGCTGAGCATCCGGCCGGGGGACTTCTCTCGCTCCAGGGGGCGGCCAGAGACTTGTCCCT
GCGCAGCTCGGTCCGCCCCTCGCGGTAGCGGTGGGGTGTGCTTGGCTCTCGCGGGTGGCTGGGGCCTTC
GGGCGGCGCTGGGCTGGAGGCCACGCGCTTGGTGATGTGCTCGTTGTACGTGGGTGGGCCTCGCTTGTTG
GGGCTGCTGGCGACACAAGAGAACGTAGGGAGCTGCG
162; I vs SW; chr17: 34157398-34159854; 17; PCGF2-PSMB3; DIVERGENT_PROMOTER
CGAGAGGACCCGGACCCCGGCGGGGAAGGGCGCCCTCCCCCGGCCTCGCGGCCGCCCCAAAGCACATCC
CCTTCTGCCGGCCCCAAGTCCCCGCGCGTCCACGGCGCCCCTGTGCCCACGGGAGAGCACCCCCGCCCAG
ATGGAAAAGGGGGTAGACCGGGCAGAGCGAGAGGCGGCTTTGGCTCGTGGGGAGCGGCGACCCAACCCA
GCGCGCATCCCGCAAGCCCTCCCGGCTGCCCCGGACCTTCCCCCTCGCTACCTCGGAACAGGGTCTGCCC
GGGGGCTGCTGCACAAAGAGGGGTGGTCGAGGGAGACGCCAAATCGTTAAGACGGGGAGCCCGTTTCGG
CCATCTTGGAAGAGAGGAAAGGGAAAAAGGGACAGAAAAAAGGGAGAAAGAAAGGCGGACGGGGCAAGC
TGGGCTAGGGACTGACGGGGCGCGGGGGGTGCGAAGGCAGGATCGGCTCAGAGCCCCCCCTCCCATCGG
GGCTTGCGAAGAACGGCCGGCCCCCATCCCAATCCCCAGAGGGTTACAGGCCAGGAGAGGGAAAGGCAG
GGGGAGTCCGCTCCGCTTACCTGGGTTCGGGGTCCGGTGGGTCTCGGGGAGGGGGGGATGGGAGGGAGG
GAGGGAAGGGAGGGGAGGGGGCCGCAGCCGTGTCGCTCGCCCGGGCGGCGGGAGGGGAGAAACCTACG
GTAAGAAAGGAGTTTGTGAAAGCGGCTTGGGGTGGGAGGGAGAGGGGAGGGGAGGGGACCGAGGGGGG
AGGGGAGGGACCGGAGTGTGGGGGGGAGACAAAATGGCTTTTTTCCTCCAGACAAGGTAGGTCCCGCCC
ACCACTCACCCACGTGACCTCATTCCTTCAGGATGCTGGCAGAGACGGGAAGAGGAGGGGGAGGCTGGC
GCGGCCGCTCCCCGCCACCGGCTGCCGGGTCCCTAGCCAGGACGAGACCCCTCCCTTCCCATGCGGCCGC
CCCGACCCCGGAGGATGGATCTCTTATGTTACCTTCCGCAGTTAGCCCCCCTCCCTTCAAAATATGGGTTC
CCCCCACTGACACTGTGATGCCCATCCCTAACTGGGGCGCCTGGAAAATGGTGAAATGGGGACTGGGCTG
AAAGGTGGCTCGTGGTCCTCCACGCCCCGGCCTAGACCAAAGGGCGCGGGGTCCGGCGGGGGACGCGAC
GCCTTCAGCCAGGCGTCCGAGCGATTTTCATT
169; I vs SW; chr17: 56827843-56838048; 17; TBX2; INSIDE
CGGAGGCGGCACAGCTGGAGCCCGGATTGTGGCACGCCGTCACCGTGCTGCTCCGGGGAATCCCGACCC
GCTCCCTGCGAAAGCGTTTCCGAACGCGAACCCAGAGCCTGTGAACGCGCCGGCAAGCCCCCACTCCCCC
ACCGCCGCCCGTCGCAGGTGGGCCCGTCCTAGGGGTCCTTCCTGCGCTCTACCCCGTCTCTCAAGTCACT
CAGTCGATCGCCCCGTTCACGCTCCCGTGATCCCAGACATCCATAACCACGATCTCGCCTCCATGCACATC
CAACGCACGACGGTGCACAACGTGCACCTGACTTCTGCGGACCAGGTGTCTCAAGCGTACAGCGGCCACC
CGCGGAACCGCGGCCCGGGGCCAGTGAGTCGTCTGCAGCTCCCCGGGTTAGGGGATTCCCCAGAACTCC
GGGAAAGTCACCCGAAGTCCATCCGGGATGCGGCCTTGGTTCTCGGCCGCGTATCTCGCCCTTAGGTGCA
GAACGACGCCCTTCCAGGGCCCACAGCTGCCAGGCTGGGCCTTGCCCTCGCATCCCCCGGGAAGACCAGG
GACGGGGCCACACAGGCCGTGGCTGCGGAGACGCTTCCCCGGGCCACCCCGCGACCAGGAGGGAGTCGA
GCCGCCCGCTCTCCCGCGTCCCCCGCCCCATCCCAGCCAGTTGGCCCCACCCTGCGCGGGATAATTGGGA
CGGGAGGGAGGCGACGGGAGGGCGGCGGCTCCAGAGAGACTGCGCGCCTGTCAGCGGCAATTTGTTTAA
GTGGACGGGACGGGCCGGGCCGCTGCGGGCTGGGGTCACCGAGGCCGCGCCCCCACCCCAACCAGACCT
GGGACCGCGGGGGAGCCCGGTCCGGCCGCTAAACCGGGCTGGCTGGCGCCAGGGCTCCGGGAGGTGCG
GTCCGGCGGGGAAGCCGTGATGGGAAGCGACTCTGTCCAGGGAGTGTCCTTCACCACCACACTCCTCACG
TCCAGGCAGTGATGACGGCCTGGCGGCACCCTCACAGCGGGCCCATAGCACGGGGCCACACACGTCCCCT
GAGCTTAGCCTGGGCACATTCGTCTGCCACCGAGGGCTTAAGCCAGTCTGCAGCCCGCGCCCCGTCACTC
GGACGCAAGTCCGTCGTCCGCTCTGCCACGCGGCCGCACAGCCCGGCTTCCTGCTGCCCACTGCCCGCGG
GGTCACGCAACCCCGGCCCTGCACA
270; I vs SW; chr21: 37857725-37858416; 21; chr21: 037857850-037857894; Unknown
CGATTTCCGCAGATTTCCTGCTGGAACGTTCTCTCGGGCCTCAAGTTTTCCTGAGAGGACGACGTGGAGA
GTGGAGACAAAGATGCTCAAAAGCCAGGAAATCGCAGGCTCGGAAGCCCCCACGCATCCTCTGAACGCAG
CGCCATCTCGGGGCTGCGGCGGGACCAAGCGGGACGCTTGCAGGCTGTCGGCGGCGGGGGCCGCGAGCC
GCCGGCGTAGGCCGCTCCAGCTGGAAGACCCCACCGCTAGGGTTCCAGGGGGCTGCGGACGCTTCCGAG
GGGCCCAAGGCGAAAGAACGCGCCCGCTTGTCGGCCACGTGACCGTCCCCGTCCGCGTCCGCAGCGACC
ACGTGACTGTGCGTCCGCGGCGTCGATTGACTGGGAGCTCCCTGGCCACGCCCTAAGCGCCAGCCCCGGG
CTTCGGGGGGCGGTGCTGCTGCGGTTGCCATGGCGTCTTCCGAGCGCGCAGGCGGGGCCCAGAGTAGCT
TTTCGGGTATTTGCTACCGGCTCTCGGTAGGGCTGGTCACCTTTGCTTGCTGAGCTTCGCGCCCTGCGTCC
TTTGGTCCCCAGCAACTTGCAGGGCAGCCGTCCCTCATGAGGCCCTCCAGCGAATGCCCTAAAGCTCCGA
AGTTGCTCCGGAGGAAACAGGCTTGCTCCGAGGGTGCACGTCCTTACTGCCCGTGACGTCG
271; I vs SW; chr21: 43350621-43351134; 21; CBS; INSIDE
CTGCTGCACTTGTAAAGTGGGTGCTTCTCAGCTTCATGGTTTGAGGGGTGCAGCCAGCTTCGGCCTAAGT
GGTGTTGAGGGTCGAGGACCCAGCACCCCCACACGGGAAGCGCGGTGTCCCGCCTTCAGGCTGGAGTACT
CTGGCACCCTCTGGGGTCCCGAAGTGCCTGAGTACCTGTTTGAGCCGCGTGTAGGTGACTGCGCACCTGT
TTGAACTGCGTGTAGGTGACCGCGCACCTGTTTGAGCTGCCTGTAGCTGACCGGGCACCTGTTTGAGCTG
CCTGTAGGTGACCGCGCACTGTTTGAGCTGCCTGTAGGTGACTGGGCACCCGTTTGAGCTGCCTGTAGGT
GACCGCGCACCCGTTTGAGCTGCCTGTAGGTGACCGGGCACCCGTTTGAGCTGCCTGTAGGTGACCGGGC
ACCCGTTTGAGCTGCCTGTAGGTGACTGGGCACCCGTTTGAGCTGCCTGTAGTGACCGCGCACCCGCTTG
AGCTGCCTGTAGCTGACCGCG
283; I vs SW; chr4: 40134579-40135662; 4; FLJ20273; INSIDE
CGCGTTGTAGGGGTAGCCGTAGTAGGCCAGTGTGTAGGGGTCGCAGGAGTACACGTAGCTGGGCTGCTG
CGCTGCCTCAGCCGCGCCGCCGCCCCTGGCTGCCTTCTGGTAGCGCGAGTACTGCTCCTGTCCACGGGCT
TGGCCAGCGTGACCTCCAGGCACGAGCCCTCCAGCTCAGTGCCGTTGAGGTTGTTCATGGCATGCACGGC
ATCCTCGCGGCTGGTGAAGTGCACGAAGGCGTAGTCGCGGATCTTCTTGACGCGCTCCACGCAGCCGGGG
TTGAACTGGCCGAAGCTCTTTTGATGGTGTCCTCGGTGGTCTCGATCATGAGGTTGCGCACGTAGAGGAT
CTTCACGGTCTCCATCACGTCCTCGTCCACGTCGATCTCAGGTTCGGCCCAGTCCACGGCGATCTGGTGGC
CCCACAGCTGGATGCGGCCAGGCATGAGCTTGCGGCGAGCCATGGCAGCCGGCGGTGGCTCTCGTACTCC
ACGAAGGCGAAGCCGCGGTTCTTCATCTTGTCGGCCGCGCTGGCGTAGACGATCACGTCCAGCACGCCCT
CGGTGACCTTGGCAATCTCCTCCAGGATTTCCTCGCGCTTCTTCATCTTGGGGATCCCGCCGATGAAGAGG
CGGCAGTTGTCCCGCTGCAGCACACGCCGAGCAGGCGGCCCGGGCGGATCTCGTAGTTGTTGAGCTCACG
CACTGCGCGCTTGGCCTCGTGCTTGTGGCAGTACATGACGAAGGCGTAGCCGCGGTTCTTGCCGTCAAAG
TCCATCATGAGGCGCAGCTCGTAGATGCGGCCCACGGCCTCGAAACGGGCACCAGCTCGTCCTCGTACAC
GTCGCGCGGGATCTTGCCCACGAAGACCTCGCAGCCACGCTGCGGGTGCGGGCCCTCCCAGCCGGGCGG
TGGGCCGCCGTACTTGCGCTGCCCGTTCTCTTGCACCATGCTGTAGCCCGTGCGCTCCATCAGCGCCAGC
AGTGCTGCTCGTTGGGCGCGCCCGCCACGCCCTCGGGCACCTTGGCGGAGGACCCGGCGGCCGAGTCAC
TGCTCATGGCTGCGGTGGAATCCTCTGCG
357; I vs SW; chr7: 27219187-27220360; 7; chr7: 027219187-027219246; Unknown
AAGTCTGGAGATAATTATGTCGTACAGTCGCAAACATTATTCCGTTCTTACTGTAAACGGCCCCGGCCACC
TTTACGAGAAACCAGGAAACTTCTGAGAGTTACTAGCAGCGTTTACGCGGGCAAACGAGTTCTTTTTCTTT
CTCTCCCGGATTGTTCGAAGTATCTATCGGGCGGCTTCGATGCCAGGTTCAGAGGCGCGCCAGGGAGAGG
GCGCCCCGCAGAGGAGCGCAGCGGAGAGGCCTACGCAGGTCCCCGGTGCCCGCGGCCCTCGGAGGCCGG
GCCCTGCGTCTTGGCCAGCACTGGGTGGCAGCTGAGGCTGGTGGCCCGGAGCCCTCGCGGCCGCGGGCA
GGCCCCTTCTTGGGCAGGGTCGGGCACTCCCGCTGTCCAGGGCTCTTCGGCACCCTCCTTCCAATCAGGT
CGCTCTCCCCTGCTCCCCAGACTCAACTCCTCCGAAGCTGCTCCAGGTTGAATGTGACCGCTAGGCCGACT
CCCTGGGCCCGCGAGCAGTTCTCGAAAGGTGCGGACTGAGCCCTTTCTGGGGTGGGGTGCGGGTTGGTTC
TCGCAAGTGTGACCCAGGGTGAACTTGCTATTTCGGGTCCCGGGTGCTGCAGGGCCAGGAGAACAGCTGG
GATGGGGGACCCCGCCTCCACCCTCGGGCCGGCACGTCCGCGCCCTGTCAGGTCCCCCTCCCTCCTCTAT
GATGGCCAAGGCGTGCGCCAGGGCTATCCGGGAACCTTGTAAGGCCTCGTGCTGGCACCTAACCCCACTC
GCGGCACACTTCCTCTATGTAGTCTGCGGCCCCGCCTGCCAAATAGAGTGACCAGTGCAGGGACAGAATG
CCAGGCTGGTGGCCGACCGCCTGAGGGACAAAGGCGAGCATTCACAAGCCAACAGCAGACCCCTGCCCCC
CATATTTCCATTTCGCTCAGGCTTTTAGGACAAAATCAACAAGGCCGCAGAGTGGTGCAGGCGCTCACCCC
GGGTGCAGCCTGGGGAGCCACTGGTTCCGCGACCCTGGGCATGAAACTCCTCAAGGGCGGCCCTCGAGA
CGCAGGGGAGAGGATGCTGCCGGCGCCTGCCCGAGGGCTTCTCTGCGGGAAGCGGGCAGGCACCCCACC
GGAGTCATTGCCGGGACCCTCAGCGCAACGCGGGCCTGTTCCTCTCG
373; I vs SW; chr7: 156895132-156895886; 7; DNAJB6; INSIDE
CGGAGATGGCGCGTCTGGATTCAGGGAGATCGTGCGGCCAGCTTCCCTCCCTCTGCTCTGGATGGGGGCC
GGCCGCCGCCGCTCACTCACGGCTCTCTCTCTCCCGCTGTGCCTGCAGGTGTGGCCGCGACGATGCCCTC
GCTGAGGAGCGCATGCGGAGAGGCCAGAACGCCCTGCCAGCCCAGCCTGCCGGCCTCCGCCCGCCGAAG
CCGCCCCGGCCTGCCTCGCTGCTGAGACACGCGCCTCACTGTCTCTCTGAGGAGGAGGGCGAGCAGGACC
GACCTCGGGCACCCGGGCCCGGGACCCCCTCGCGTCCGCAGCAGGTGTGCAAAGGGAGGCAGCCGTGGA
GCAGGCGCAGAGTGAGACTTCTCTGGGTGCCAGAGGACAGCGAGGACACAAACCGCGCCTGGGCTGCTG
TGTTCTGACCTGAGCGGGCGTGGGCGGTCGGGCGGGGCGGGAGGAGGTAGCCTCCTCTGCTCCTCTCCC
GCTCGCGGCGCCCCACGCCACGGTGGCTCCGGGCCCCCCACCGTTAAAACGGGGTCCGCGTGTCCTGTAC
GCAGCGTGTTGCTCCGCAAAGGATGACAGAGCTGCCACGGCAGTGCGAGGTGCTGCTTTTACCGTAGACG
TGCCTTTTCGTAGCTTTAGCGTAGAGCTTGAGGCCTGTGGCTTAGGCCGGGTGGTCTCGTGCTGGTGGGG
TCTGCGTTTGCCCCTGCCCCTCCGTCAGCTTCACCTTCTCGTGCCTTCTTCTGCG
389; I vs SW; chr8: 132985505-132986242; 8; chr8: 132985506-132985550; Unknown
CGTAACGGGCGTGGGTCGTCCGTCGCGCCGCCCGGCGAGGAGTGGGCTGGCGGCGGTAGCTGTCGCCCG
CTTGGTTGCGTGACCGCGGGGTCCGCGTCCGCTCCCTCCACCCTTCGCCCTTCGCCCTCGCCTCGTTCCG
GCCTCCGCGGCCCAGCAACGGCCGTCATGGTGCCGTCGGCGCTCCCTGCGCGGCCCCGCTGAGCCTCGGT
GCGGCGGCGAGCGCGGTCGAGATCGCCATGCCTACCCGTGAGTGGCCGGCCGAGGGCCGGGGGCGTTGG
GAGGCGACTGCCTGCGCGACGGCTTGGGCCGGGTACTCCTCCCGGGCGGCTGGGGAGGCTGGGCCGCGC
TGAGCAGAGCCAGGAAGTGTCTGCGAGCGGCGGAGTTAGTTTCGTTTCGGCTTAGCCTTCCGGAGATGGC
GTGAGCCCGTTGCACGGATCGGGAAACTGAGGCCCGAACGTTAAGGGAACTGCGGGACGCGCTGTTAGG
AGGCGGCAGAGCTGGTGGTAACCTGACCCGTGGGATTTCAAAGTTAAAGCCCTTTTCCCACGGCCACACG
GCTTCGTGGGACTTTATGGAAATATTGAAAATAACTGCGGTACCATTGTCAGTCCCTTCTCACCTCGGGCC
GGACGTCGCTAGTGGAGCGCCGGCCCCGAGTCCCTTCCCGCGGCCGCCAGACAGACCCCCGACAGCCTAA
CTCGGCGTCCGTATCGCCGTCGGGGCGGCTGAAGTCG
12; SW vs I; chr1: 68288825-68289104; 1; DIRAS3; INSIDE
CGGAGGCACGAACCAAGCAGCCTAGAAGACAAATGCGCTGCTCGGAGAGACTGCCGCGGCAACCAACTG
GACACCCCAAGAGCTCACTCCTCCGCGGTTTTATATTCCGACTTGCGCACAGGAGCGGGTGCGGGGGCGC
AGGGAGTGTGGGTAACAGGCATAGATTCCGCTTGCGCAATACGTGGTAAGAAACCAGCTGTGAGGGGCTG
GCCCAACGCAGAGCGGCGCGAGGTCCGCTTGGCATCTACAACAATCGAGGGGCTAGTCCAGAAGTTCAAG
15; SW vs I; chr1: 71284766-71286392; 1; PTGER3; INSIDE
GCTCAGCTAGTAAGTGAGGAGCTCAGCTCTGAAGCTGTAACCAAGACCGCGCGGGCAGGAGGAAAGGAC
ACTTCAGCGCTCTGCGGTTGCAAACACACCCCTGCGGGTGCTGCCACTTAGCAAAGTCTAGGTTCCCGCTT
ACTCGCACACGCATCCTGACTTCCCCCAACCCTGGAACTACCTACCAGGAGCGGAGACCAGCAGACCGAC
AGCACGCACATGATCCCCATAAGCTGAATGGCCGTCTCGGTCGTGATGCGGCCCCACTGGGCACTGGACT
GAGATGCCGTGGCCTTGGCCGGCAGCGGGACACCAGGGCCTTAATGGTGGCCAGGTTGCAGGAAAAGGT
GACTGTCAGCGCCAAGAGCCCCAGGAAGGCAAAGGCAGAGGCGAAGAAAAGGTTGCCCCAGTTATGCGA
AGAGCTAGTCCCGTTGCCCCCTCGCCCGGTGCTGATGAAGCACCACGTCCCGGCCACTGGACGGTGTACT
GGCCCACGCCCAGCACCGGCAGCAGGGCGAAGGCGAGCACGGCCAGCCACACGCCGAGCAGCACAGCGC
GGGTGGCACGCGTCTTCATGTGGCTCGCATACCAGTGCGGCGCCCTGATGGCCAGCGCCCGCTCGACGGC
CATGGCGCTGGCGATGACAACGAGGAGAGCCCGAAAACAGTCATGGTCAGCCCGAAAAAGGTGCAGAGC
CGCCCCGACGGGTCGATGTGCTCCCAACGCTGCTTGGACAGGTACACGACGATGACGACCGGGGTGGTGA
GAAGCTGCCCGACCAGGTCGGTGAGCGCCAGCCAGCCGATGCACAGCAGAAGGACTTCTTGCGCTTGCTC
TCCCGGCGCCGGTAGCTGCGCGACACGAGCAGCATGGCCAGTGCGTTGCCCACGAAACCAGTGAGCAGC
ATGGTGATCGGGAAGGCCACGGACACCGATCCGCAATCCTCGCCAGACCCTGGAGGGCGCGTGAGGTTG
CCCCGCGCCTCGGGGAACGCTCGGGCGCCCACATGCCTGTGTAGGAGTGGTTGAGGCGGGTGCAGAAGG
GGGCATCCCCTCCGTAGCCCCGGGTCTCCTTCATGTTGGCTTCGAGGTGAGGAGGGGATGGCGTCCAGAG
AGCCGCAGCGGGAGGGGGCAGACGCGGCGCGGGCGGCGGCGGAGGTGGCGTTTACCGCGGCTGGGGCT
GGGCTGCCCCCCATGGTGCGGGGCGCAG
21; SW vs I; chr1: 119333484-119333719; 1; TBX15; INSIDE
ATTCTTAATTCCCACACCTCTTCCCAAGTTACGCCACCGGTCGAGGACGGCAGGAGACCCCCGAGTGCAG
AGAAAGCTCAAACCGGCAGCGAAGTCGGTCCTAGCCAAGCTGAAAAAACGTCTCGGATTCGCGGACAGCG
GCCTAGACACAGCCCGATCTTCCAGTCCTAGTGCCCTGGTCGAGACGGTTCTATCCTTTTGCAAAGAAGCC
GGAAAGAGCTGGGTCCCGGGGGCG
26; SW vs I; chr1: 178464743-178471598; 1; LHX4; INSIDE
CGGGGTGGGCTTCCCGCGCCTGCAGCCCGGAGGCGTCGAGCGCCTGATGGAGCGTCAGAGGAGACCTCG
TCCCAGCGTTGGGCCTTCTGTTGTATTTCTGCCAGAAACTCGCGTTGAGGAGAATTTGTTTAAGCGTTTCT
CTACCTGTCCATGCATCTCGTAAATACAGTAAGCATGGCAAGCCCTTTCGCTGGTTAACCCCGGCGTCCGT
GTGCTCACTGCCGCCCTGCACGCACGAGGTCGCGGATGGTTCAAAGCACCCGCGGTGGCAGCCGGAGAG
GCAGAGCGGGCTCTAGGGACTAAGACAGGGCCGAGCTGGACGACTGGTGGCAGGGCGGCCGGGGAGGCC
CCGCCGCGGGGAGGTTTGGGCCCCCTACCCTGCGGAACTGGAGGCAAGTGCGGACTCCGGCTGCAGGCC
GCGGTCTGCGGGGACGCGCGCGGGGGGCCTGCGTCCCGCCACCTCCGCGCACACCCCTGGTCCCCTTCC
CCAGCCCGGGCCGGCGCCGCCCGCCGCGTGACTCGCGCGTTCCGGGCCGAGTACGGGCTGTCCCTTGGC
CCAGCCTCAGCCAGACGCGGGGGAGAGAGAGCAGGGGCTGGGAAGTGCCGGCAGGAAAGGAATTGGCCA
GGGGAAAGAGGAGGAGGAGATAGATGGAGTCATCGGTTACGGAGCGCGCTCCGTCCGGCGGAGCGAAGC
CGGGGACCGAGAGCGCGCAAGGCGAAGACACAGCGACGCAGCCCCGTCCCCGGCCTCCGGACCGCCTGC
CCCGCTCGGCCCCGGCTCGGCTCCGCCCCGCCCCTGGGTCCGAACGGAGGAGGAGGAGGACACGAGCCG
CGCGGGCTTGGAACCCACGAAGACCCGCAAACCCAGGGCGCCGCCGTCTCCGACCACCTGCTGCCGCGG
CAGGCCATCAGCAGAATTTATACCCAGGGCGCGAGCCCGCCACGGCTGGGCGGAGGCGGAGGCGGAGGC
GGGGAGGGGGGGGGGGTCCGGCTTGCGAGGCCCCGCCCCGCTCCCTGCCGCCCCGCCCCCCTCCGCCCC
GCCGGCCTCACTCGGGGCGCCGGGACCCCCACTCCCTCCGGGGTCGGCTGCCCGCCGCCGGGTTGGGGG
ATGTGCCGAAGGGCGGGCCTCCCTGCGGAAAGCGACGTCACGGCCGCTCCTCAGTGTGAATGAATCAAAA
CGCCCGGGTGACCGCGGCCTCCCGGGCGGCC
40; SW vs I; chr10: 7449476-7449790; 10; SFMBT2; INSIDE
AAACCACTCTGAAAGAACTGTGAGACCTTTGCACTAAGACCATTAGGGATTCTACGCAAGGTTCTCTCTGC
TCCTTGCAAAATTACAGGCGTCATGAAGGATGGCGGCTCGTAAATCGAAGCCTTTGAACAGGGGCTCACC
GTCCGGCGGCATCAACACCTTGTTGTTCTGTGTGCACCACCCCACGGGGTGCAAATCCGCGATGACTACG
TCACACCAGAAGTCGGCCCTGCGGTCCTCCCCGTAACCGCAGTAGCGCAGAAGCAGCAGCTGCCCGCACG
TGGTAATGATCGTGGCCACCAGTACGTGTCCG
41; SW vs I; chr10: 7489383-7495345; 10; SFMBT2; INSIDE
CGGCAACCGAGCCAGATCCAAGAGGGGTCGGCCTCGTCTAAATTGGTTTCCCACCAATGGCCTCGGATCA
GCCGCGGCTGTGCTGCGGGAGCCCTCAGGACGCGGCTGGGGTTGGTGCGCGGGGCCCGGAACCCCAAAC
CCGGCTCGGTTCGGCAAGGTTCAGGGAGACAAGGTAGAGAAGGCTGGGGTGAGCGAGAAGTCGGGCGGC
CGATCGTCAGGGCCACGAGCCTCGCCTTGCCTTCTTGGAATCCCACCCAACTTTAAAGGCCCAAAGATCCT
GAAAATTCCGAAAGCGAAACGCGAGCTGGTCTCCAGAAGTTTGAGAACGGTCTCCCAGGCTTTCCAGCGT
CGTCCCGGGATTCTCGGACACCACAAACGCCATCAACCACGAGCACCGGTGTCCGTGGCTATTGCCCCGA
ATGGTCCCCATCCGCGTCCCCGGGAACTCCCTCGGCTTTTCGCGCATCCAGGCCCCAGCCCCAGCTACTG
GTGCGCCCCGAGCCCCTAGGTGCCAGAGCGGTGGTCGGCCGGGCTCCTGCCCAGTCTCGGCTCCTCCCTC
CTCCCCACCAGAAGGAAAAACTTGGGCCCTTCGAGAACCCTGTGGAATGTTCTTTGTAATCAACTGTACAT
CCGCTTCCACGGCCGGCCTCGTGCAAAATCGCGGGTTTCGGGGCCTTGGAGCAAATTGCGCTTGTCAGCG
GCGACGTCAGGAGGACAAGGGGAGGGGTTCGCGGCTGAAACTGCAGCTTCGCAGCACAGAGCCATTTTA
GGCTGCTCCCCACCTCGCGGGGCCCATGGGAAAGCCGGCCCCGGGAGGCGCGCCCAAACGCAGGCTGGA
GGAGCCACGGACGCGTCCTGGCCGGCGTGTCGCCATCGTTCAGCCTCGCTGCCCAGGTGGGAGGGGTCA
CCTGCCGCGGGGTCTCCAAGCCAGTGCCGCTTGCTCCCGGCCCCCACCCACTGACAGCACGGCGTCCGAG
TGACCCTGTCAGCCTCGTTCTGCGCTCCTGCAAACCACGTTGCTGCGCTAACTACAAACCTGGCCAACATG
TCTTTGTAACCCTATCATTTAAAAACGCTTCCAGGCACCTGGCCGCTGCCAGATCAGGTTCGCGGGCCCGG
AGGAGGTCCTCCCACCTGCCCCCGCCAGCCCCGGGGACCGGCGCGGCCTCCGTGTGGCCCCCGCCCACG
AGGTCCCTCGGGCAGGAACCG
112; SW vs I; chr14: 37746906-37747538; 14; SSTR1; INSIDE
CGGAAAAACTCGAATGTCGCCCTGCCGTTCCTGGGGTTGGTGACAGGTCTGGTCATCGCACGGCGGCAGC
TCCTCACCTGGATTTAGAAGAGCTGGCGTCCCCGCCCGCCCAAGCCTTTAAACTCTCTCTGCCAGAACCCG
CCAACTCTCCAGGGTACAAAGTACAGCAGGGACGCGGGTGGAGCCCTTCCAAGCGGCGCAGCCTTATCTT
TCCCGAGTGAACACCTAGGTGGATTCCCAACACCGCGCCTGGCACGTTTCTGGAGGGAGTCTCAAGCTCC
TCCAGAGCTCCCAGCTGCCGTCCTCGTTTCTGCAGTCGATATTCCTGTGGGAGACACGGGGGGCTCTGAG
CGCTACGAGCTTTATTAAGAGATTTGCGAATGGTTCACTCAGGTCCCTGAACACTCCCAATAGCCTAAGCT
GCCTGCTGTGTTATAGCGCAGAAGCCCCTAACGCACGGTGGTTGTCCTTCTTCTCATAACGCTCGCAGCTT
AGGGCCAGTTTCCGCGATTCTAAGAGTAATTGCGTGGGCACCTGTGCTGGGGCCAGGCGCAAAGAAGGGA
GTTGGTCTGCGCGAAGATCGTCAACCTGCTAACAGACCGCACATGCACTTTGCACCGACCATCTACG
118; SW vs I; chr14: 53488428-53488700; 14; BMP4; INSIDE
CGGTAAAGATCCCGCATGTAGTCCGGAATGACGGCACTCTTGCTAGGCTGCGGGCGGCGGCGCAGCCCAA
ACATCTGCAGAAGTGTCGCCTCGAAGTCCCGCAGGAGCTCATGGCTCTGCCCTGAGCGCGTCCTCCCGCG
TGGCCCTGAATCTCGGCGACTTTTTTCTTCCCCGTCTCAGGTATCAAACTAGCATGGCTCGCGCCTCCTAG
CAGGACTTGGCATAATAAAACGACCATCAGCATTCGGTTACCAGGAATCATGGTGTCTCTG
147; SW vs I; chr16: 52873104-52882105; 16; IRX3; PROMOTER
CGCGAGGATGGGCGGGCTCCACGTCTGGGGGCGCTGTGAGCAGGGCCAGAGCGAAACCTCAGTCTGAGT
TTACGAACTGGGAAGGAGCCTGAACCCCAGAAACACCGTTAACAAAGAGGGCGAACGCAGGGAGCCGAG
GAGACGTCTCCTTGGCCTCTGGGGAAGGGGCTGGAGGAGCGAGCCAGCTGAGAAGCGGCTTTGCCGGGT
GTCCACTAGCGGTTCGCCAGCCCTCTGTGCGCCCGCAGAGTGACGCAGAGGCCGACACAGTCCCCTCCCC
ACTCGCCCCTGGGGCGCCGCCGACCTTGATCACCCCCTTCGCGGAGGGAACTCCCAAGGCGCGGCGCTGG
CCGCTGGGTCCGCATGGCCCAGTCCTGTCGGGCTCCGCTCTGCTGCCGCCGAGCTTCGAAGGTGTGCAGT
GTTGAGCCGTGTCTTGTTCCGTGGCTTCGAGGGGTGTGCGCGCTTCCTATACCTCCCGGAACGCGCGAGA
TAGTCACACGCGCCACTTTGAGGGTCAAACACCCCGCATCTGGCCACACTGTACCTTTACTAACGTGGGGA
GGGGGCAAAAAAATGTGTCTCTCCTTCTTACCCCGAGGTGTCACTCGCCCAAACACTCCCTACAACTTCTT
CAAGTCAAACTTGGCAAGGTTGGCTGGCTGACTGCGAGAGGAAAAAGAGGGCGCGGAGGGGGCGCGGCG
CGCGGCCGGGTGTAGAGGCCACGGAGGCGAGGCGCCGAGCGTCCCCTTTGTCCTGTAGAGGGAGCTCCA
GCCCCAAATTTCCCTGCTGCCTCCCCCGGCCCGCCCACCCCAGGCCCGCTGGAGCCGGAATCCCGGCTGG
AAAGGTGCGGCGGTCTGACACCCCCGCAACCCCCGCGCCGGGGCCTTAGCAGGATGCCTCTTCTAGGGCA
CGTGGGAAAACCCACCAGGGTGCCAAGACGCACAGATGCTCCCAGGACCCGGGCTCCCCAACTCTCAACT
AGAGCTGGGCGTCACACATCATCTAGAGGATTATGTACCCCTAGGCGACCCTCTTCTCCATATCCGCCTCC
ACCGTCACCCCACACCCTGGCATCTATAAAGAGGGAAGGGGGGCAACCGGGTTGGAAGGAGGATGGAAT
CTGGGCTTGCACAGCCTCTTATAGGTAACAGTGAGAAAGCCTAACTGTGTCGATCAAAGAATGGGGACGA
AGGGAGTGATGAGAACACGACC
151; SW vs I; chr16: 85098883-85102729; 16; FOXF1; PROMOTER
CACACACACACACACAAAAGTTGGGAGAGAATGTGAGAATGCTTGTGTTCGTGGACGCGTGCGCACGTAT
GGAGCGGCGGTACCTATGATTATTTGCGCGTGGCGCCTGGCTATGCGTGGGCGAACGGCAGTGGAGAACA
TGTGGGCGTGCATGAAGTGTGCACTTAAACCAAAGTGTGCCCTCCCCGTTGGGCAGGCCTGTGTGTTGGT
CCAAGGGTTGGGAGCGCCTGAGCTGTGTGAGGGTCGCTGGGAAGGGTGTTTGAGGCCGTGGGCGGTGCG
GAGCGTGTCTGTGTGCGCGGGGCTGAGCTGGTTGTGTGAAGTGGTAGCGGGTCTGCCAGAGAGCGTTTAC
CTGCGTGAATGCACAACCACACACTACGGGTCACGTCCCACACTCATTCTTTCCCTAGGCGGGCCAGGCT
GTCTGCACGCGGAGACCCAGAGAGGCCAGCGGAAGGGCAGCGCGGGAAGGCGCTCTCTTCTCCCGCGAG
CGCAGATCTGGCGGAGGAGGCGGCGACTGCCCGGCAGGCTGCGCCGGCGAGCCCCCCAGCTCCTCTCAC
CGACGTGCCAGGCGCCCCGAAGGCGACAGGCGTCTCCCGCCGAAAATGAAGGCGTCCGAGCCAGGAAGG
TGGGGGCGGGTAGTTAGGGGAGACAAGGAGTCCGGAGAAAACCGAGAGGCGGGTAGGCTTTGAACGCGC
CGCGCCGCGGGCCGTGCTGCGAGCCCGGCACACGCCTCTCGCCCCAGCTCGCGCTGGGGCTTGGCCTCTA
GGCTCTTCGCGATGACCCGCGAAAACACCCCTCGCCCCCCTCTTCTCAACCGGAACCCTGGAGGGAGAGG
CCGCGCCCGGCCAGCAGTCGCTGCGAGAGCAGCACTCACCTGGGTCTGTGCGCGCCGCGATGCGCCGGG
GCTCCTGCGCTGTCCTGCGCTCCGCTCTCGGCACCACCTTTCGTGGCTCCACCGCCCCCAGCCCGCACCC
GAGCGCTGAGGTGCAAGGGCAGGTCTGCGTGCGAGCCCCCTGCGGGCTGGCAGCCAGGTGCGCGAGGGC
CGCCCTTGCCGGCGCTCCCAGCCCGCGCTGTCTGCTCTCAGGAACCTGGCCTGGCGCGCAGTGTCAGAGG
CCCCGCGGCGGCGGCAGGCCGAGCCCACAGGGGCATTAGGCCAACTCCCCCTCCCGCCCTGCGCACGCG
GAATTCTCTATTATTATTATTAAAGAA
180; SW vs I; chr17: 75377960-75381951; 17; CBX8; DOWNSTREAM
CGAGCAGGAGCAGGCGCGGCCCCGGATGTGGAGCCAGGCTTTCGGGAGAGCCCATTTCTACAGGGATTC
GGCCCGACGGGTGCCGGGCCGAGCTCGCTCGGCCTTTGTTAGTTTCGGCGCCGCTGATTGATCGCCTAAT
CCAGTGGACCCTGAGAAGAACAGACTGGGCTGCCAATGGCCCGACCCCACGCCGCCGCGACCTGCCCGA
GGGCACCGGGAGCGATGGGTGCGGAGGGGCTGGGAGGACGGTCATCCGGGCGGCTGGACCTCTCCTTCC
TCCCCTCCGCCTTCGTGGCTCGGCGCCGGGCCTCAGGGAGGACGCAGAGGGGGCGCCCGTGGCGGTGGG
CGCCCAGCGGTACCTTTGGGTCGGGGGGAGGTAAGGCTTTCTCAGCTCGGGTTCGGAACCAGAAAGCCAC
CGGCCCCCCGGGGGTAAGGGGTGGGCGCCGGCGACCCGGGCCGACGCCGCCACCTCAGAGGGCGCGCG
CGTCCCACCAAGGTCGGCCGCCGGCCCTTCGGACGGACGAGGGAAAAGCCAGCCGCGGCTCCAGGGTGC
CCGAGACTCAATCGCACCACCTGCACCCCGGCCACCTCCGCCTCCGAAGTCTCAGGAGGAAAGCCCCGAC
CCAGCCCGCAGCCTCTCTCGCGCGTTCAGGACCCGAGGCTGCGGGCAGCCGCCTTCCACGACGGACAGCA
CGGAGTCCCGCCGGGCCCCGAGCCACGCCAGTCTCGGACTTCAGCTGGGTCCGAGGCTCCTCTGGGCCTG
GAGGGCTTTTAGAGGAGAAGAGGAAACCAGCACAGGAGCCCCAGAGGGCCGGACAGGTCTGTGCGCCAG
CGGCCCGGGCGCATGGCACAGTGCCTGGATCAGGATTGGTGCGAAGCCAGCATCAAACGGACAGAAAAT
GAATCCGATCCGACACTCTAGGAAGAGCATGAACCTTCCAATCCAACCAATGTTTGTGCGAGGCCAGGTTC
CCCGCCGCGGTGGCCCACAAGCCAGCCCTGTCCTCGGGACGCAAGGTAACCAGTCCGGCTGGAGGCCGC
CACGCACGCCTGGTCTCTGCAGTTGTGGCGGATTCCCAGGGACTCTGCCCAGGAAATGGAAACCCGTGAG
GGCGCTCCTCAAAGCCGAGGGTGGTGATGGCCAGCGAACCCGAAAAAGGGCAGGGTGGGCGCCCTCCCA
TCCGCTTAAGCAGTAGCCCATTCCACTGC
187; SW vs I; chr18: 68359955-68362770; 18; CBLN2; INSIDE
CGCGCGCGCAGGTCCCCGCCCCTCTCCCCGGGCTGGGGGCGGGGTGGGCAGGCCGACGGCTGACCTGGT
CGAAATAGATGGTCATGGTGCGGTTGCTCATCTCGGACGGCTCGTGGTTGGTGCTCCGGTGGCGGAGAAG
GCCACCTTGGCGCTGCCGGAGCGCACGGAGATGCCTAGGGAGGAGGTGACGGCGCCGTCCGCCGACGGG
CTGGAGTCGCACACCACCAGGCACTTGCCCTCCAGCACGATGGGCTCCGTGTCGTTCTGCGCCCGCACGG
GGCAGCAGGCGGGCAGTAGCACAACAGCAGGGCCAGCGCCACCCCCAGGCAGGATCCGCAGCCGCCCGG
CTCGCGCAGCGCCCCCCGGCGCCCGGGCATCATCAGCCGCAGCCCGAGTGGCCCCCGGCCGGGCGCCTG
CATCGGGACTGGTGGGAGGCGGCGCGCGGGGGTGGAGGCCGGCGCCGGCGCGAGCGCGCGGAAGGGCG
CGAAGGAACGCGCGGAGCTCGCAGCAGCCTCCGGGGGCCTTCGTCCCCGGCTCTGACGTTCAAGGCCAG
GGTCGTTCTCAGAAGAAAGGCGCCTGTGAACCTGTCAGGGCACAGAACCCAAAGCCTTACACCGGGAGGT
GGAGCCACCGGGAAGAAGGGGACTGGGAGCAGGTGCCTGCGGCTCGGGGGTTCTCCCCGAAGGCCACCC
CCTTGGTCCCGCGCACAGCCAACCCGCTTTCCGATCTGGCACAACAGGTCCGGAGAAACGCCCGGGCGCA
GCTGGCAGCGCATCCCTGAAGGCTCCCGAGCAGCGCGCGGGGCTGCGACGAGGAGGGGGCCGCGCTTCT
GCAGGTCCTCGTCGCTAAGACGGGCCCCGAGACCCTCAGAAGGCGTCACCGCCACCCCGCCCATTCACCA
GCGCGGAGGGGGCTAAGACGCAGGCAAAGAAAAACCTACGAATGCTTGCCTTCTCGCCTTCATCTCACAG
CATTTCCTTGGAGCAGACCAAGGAACCCTTTTCCTATCCCTTGTTTCCCTGCTATCCTCTATTTTTCAATCC
TCGAGATGTTTTTAAAGTCCATTTAAGTCCCTTTGGTACAGATTTTATCTGTTTTCCACCCACAGAACAAAT
CCCAGGAATCTCCTTGGGGCGAATAAGATTACTAGGGGGGAAATACACCACACACACACACACACACACA
CACACACACACACACACACACACA
200; SW vs I; chr19: 42586165-42586705; 19; ZNF569; DOWNSTREAM
GGAAGTATCTTGGCCTGCACGCGGTTTACATCATTGGGAGCACAGGCCTCGCCCTCCGAACTACGAGGCC
CAGAGCCCTTCGCGCCGAGCGTTTCCCGCCTTTCCCCTGTCTCAAGTCATTGCCCAGGGCCACTGCGGGC
CGTTCCTGCCTGTCCGTGGAGCTGCGGCCCCCGTGTTCCCAGGGTGAACGAGCACGTGCGAGGCGGTGGT
GCTTGTATCCGGGATAACCAGGTAGGGCGGCTGCATGCTTCATAGAGGCCAGCCTGTGCCGACCGGGAGC
TGTAGGACGGTCTGTGTCTGGGCTGCTTATGGGTATTCGCGTGCGTCTGCCGGTGCGCGGTCCGAGCCTA
CTCACGAGAGCGTGTGTGTGTCTTCTGTCTCGTGTTGCTATGAGGTTTGCATCTGTGTGGCTGGAATAGCT
TGTTTGTGGGGGCCCGCGCGTGACCTGTGTGTGCGTTACTGTGTGTGTCTAGGCAGGATAGTGACGGGCC
GTGTGACTGTGACGCCATCATCAGGTTGGTGAGATGGCGTGACCGCG
207; SW vs I; chr19: 63420090-63420541; 19; ZNF274; DOWNSTREAM
CGAGGGAGGACGACAAGCGGGGACGTTGGCGGAGGGGTTAATGGCGGAGTCGCGATCCAGCCGAGCCCA
CAACTCTGGGAGGCTGGTTCTGCCTCTCTCCCGAAGCGTCGCCCGGCTAAGCTTCGAGACCAGGACACAC
AACCGCCGACTATTCCAGAGCCCACAGTCGGCTTCACGCTGGAGGCCGGAAACGACACGTCCCCAAAGCC
CGCGCGCGCGGCCCGCCAGAACTGACCTACCCAATCACCGCACCGCTGCGATCAAGCGGCGACACACGTT
GCCGGGTAAGAGTCACGCTTGGCAAATAAGCAACCTGCCTCATCCAATCAGCGTCTCGCCTGCCCGGTTA
GTTCCTTGTCTTGCCCAACCAGATTCTTGCCTCCTCCATACCGCTACTTGCGTGTGCCGGTGCCTGGCCCA
ATCAGCGTCTTGCGCCTCTTCTCGCTCCCG
223; SW vs I; chr2: 72224630-72228512; 2; CYP26B1; INSIDE
CGCTTGTTGCGGTGGATGTCGCCAATGGAATTGGACACCGTGTTGGGGCCCAGCAACATGCGGGTGCTGC
GAGGCCACTCGGTGCTCACGAGGTGGTGCTCGCCCATGAGGATCTTGCGCACGTTCTCGCGCCGGTCACG
CGTATCAGCGGCCGCCCCAACAAATGCGTCTTGAACACGTTGCCATACTTCTCCCTCCGCGACGACTGGAA
GCCAGAACCCTGCGGGAGCCACACCCGGGTCTCTCTCAGGGTGCACTTCTGCAGAGGGCCCGCGAGGGA
GGGGCGGCGGACCCCAACCGGGGTACAGTCACCTGCCCCCTCTCCCCACCAAACACACTCACACAGACGA
GCACGCAGGTTTTATTTTTCATAGCGTGCACAAGAACTGCGAAGTAGGGCCTAGAGGATAATAAATAATGC
AAGGAGGCGGAGGCCCAGGGGCACCCCCAGGAGGCTGTTTTTTGGTAATGCTTTCGAGAGGAAAGAGGTA
TCCCGGACAGCTGGACCCGAAGCGGGAGTCTCCGCCCCCACCCCCACCCCCACACCCCCACCCCGCGCTC
GGGAGCCTCTCGGAATAAATATTTCCAGGCTCCGGGCCACGGGCTGGCGAGACCCCGCGGGGTGGCCGC
AGGCCAAAGATTATTATAGCGGTAAGCGGTCGGTGCCCGGAGGCAGCAACTACAGATGGGGGTTGGAGTT
TCCTCCGCTCTCCGGTGTGGCCCGCGCAGGGACCCGGCGGCCCTCGGAGGACTCTGCAGGGCGGGGTCA
CGGGCCCAGAGCCGCGATTTTCCTAATGCATTTTGCCCTGGAAATACGGAGACGGACTTTGGTTGCCGCC
CTGGAGTTTGGAACCCGAGCGCGGGGCGGGGCGGGACCGGGCAGGGCGACCCGCGCAGGTAACCAGATC
CCCGGTGGTGGCGGCGCAAGCCGAGGATGGCGGGGCCGGGGCCGGCCGGACTCTCGAAACGGCTGGCG
GAGCCGGCCGGCGCGGGTACCGGAAACCGTGGAGACCTCAGAGGGGCGGGGGCAAGGGCGTCCCGCTCA
CCTTTGACGTCGGCACTAGTTACCCCACCCCACGTTAACCCTTCTCCTGCCGGGGCAGCACCCGGCGCAA
AGGGGAGGGGCGCCACCTGTCTAGCCGCCCCGCCTGCCAGCCCAGAGCGTACCGACTCGGGCTCCAGAT
CTACCCGCTCCTGCACCCCCGAGGG
227; SW vs I; chr2: 104835284-104839920; 2; POU3F3; PROMOTER
CGCTCGGCAGAGGCACGATACAGCGGGAGAGAAGGGCAGGCCCGTTCACATTTTAATCGGAGCGCACCG
GCGGCCGCTCCTCGGCTGCGTCCTGGGCTGCCGCTCGGGCTCGGGACTGCCAGATGCAGCTCTGGCTGG
GGGCGGCGGGCGCAAGCGGGCGCACCCGCAGCTAGGGGTGCGGGGTGCACGCACACGCACGCTCATTAA
GAGCCATGTATTTATTGAATGTCCGAGTTGGGTTAGTTCATTGGAAATCCCCGAGGAGGGCTCAATTTGCC
CTTGTTTTCGTTGCCACTTTCCTTTTTTCTTGGTTCGCTGAGGTTCCTCTGTGCAGCGTTTCCGCTTGGCCG
CGTCCCCCCACCCCACCCCACCCCACCCCCGCTTCTCTCGCCTACCGGGTGCACTCCCCCTCCCATCCCCC
TTAACTCTTTCAGCTGGGTTAGAGCTGAGAAAGCATTTGTCGCCGCCAGCCCATCCACCACGCAAATCCAT
CTGAGACAGAAAGGAAAGAAAAAAAAGCACCACCATGCCTAAGAATAGAGAGCGAGCAAACCCCCCCACC
GCTAATCACACACACACACACACACACACACACACACACACACGAGGAAGCGGTGGAGCAGAGAAGGGCG
CGGCTAGCCGACCCGGTTCTTTCGCCCGGCTCCTGCTGCCACAGGGAATTCCTAAAGCCATTGGGGTCGA
ATACACTTACGATGAATCTATGGGGGAAGGTCGGACTGATTGCTTTTCAAATACATCGCACGGCTCCGCTG
ACCGGCACCCTCCAAACTCACAAGGGCACGCACGCTACTTGCCGAATCCCAGAGGAGGGAGGAGGGAGG
AAGGGAGGGAGAGCGAAGGAGGGAGAGAGGGGGTGGAGGAGCCAGGGAGCGGCGGCAGCGAGCGGTCC
GTCTCGCACGCGCGGGCACCGCGCTGGTCCTGGGCTGCAGGTTTCCCAGATGATGGCATCCGAGAACTTA
AACAAAGGGGCTGCCGCCGGCGCGCAACGGCTGCGGAAAGTTGCGGTGGCGGATTTCCAAGGAGCGTGG
CCACGACCAGAGCTCTTGGCGATGCGAGCCCCCGCTTCCCACCCCCGCCGATCAGAGAAGGGGGCCGGCT
GGTGAAGGGAAGAGGAAACTTTGAAACCACTGGGGACACACTGTCTATAGGTATTAGCTTGAATGGTACA
TCCGTGCCGCGCGCTTTACA
235; SW vs I; chr2: 124498611-124499725; 2; CNTNAP5; PROMOTER
GACTCTCATCACTACCACACCCATGTGTCTTTCCTCTCTCCGTCTCCCTGAGACGCCAGTGAACCACCTGG
GCTTGGAATCCAGAGCCCCGGAACACCTTGCAGTACTTGCCCGAAGCAACGCGCCACAGCGGGAGGGAGA
CGCAGACGCGAAGACCGGCGAGAGGATGTGCGGTGGGAGTAGCTGCGGGGTCTGCAAGCAGGGGAGCGC
GCACAACGTTAAACCTTGAAACCAGAAATCCCGATCCTATCGAGACCCATCAGCTTTTCCCATTTGGGAAC
GAGCGCAGGGGAAATTAATGCGTAATTCAAGCTCTGTTTTCCCCTCCCCTCCAAAGGTGAGGTGGGGGAA
CGCGTCTCGTTAGCTCATTACAAAGCTTTCCGTGGGAAATTCCCTCTTCCTAATGCGTCTGTCTTGCAACT
CCTATTAGCATCCTTCGACAGCGGCCTTTGAAAATCTCCTTTAAATTTCATACCTCTACTCGTTTCCCAAAT
GGGGGGAAGGGAAGAGAAAGCCGGGGGGTAGAGAGAATTTCCTTCCCCTTTCCCTCCCAGGTAGCCAAAG
CGCACCGCAGCGGCTTGGCTTCCTGGAGGAAAAGCGCCCGAGCGGGGCAAAGACCCGCCCAGGCTGCTC
TTATAGGCGACGCGGGGCGGGCCTGGCTGGGGGCGGTGCCGCGCGGCCCCGCTCGCCTATAAGGAGCTG
TCCGCCACCCGGGTGCTGATTCCAGCTCTCGCGCCCGACGAGGTGGATTTGGCTGTCCACCGAGCTCCGG
CGCCTGTCGTTCTAATTGGGTTTGGATTTGCACCGTTAAGGAGGGGGAAGAGAAGGAAGAGGCGGGCGAG
GAAGGCGAGTCCAGCTAGCGGCTGTTGCGGGGACCGTAGCCCCAGCTGCAGCTCCGAAGAATCCCCCGCC
ACGGTTTCGGTGGAGCGTCTGGGCACGGGATGGAGTGAAAGAGCGAGTGCCTCTCCAAGCGGGGGTGGG
AGGGGGCAGGCTGTGCAGAGGAGAGAGACAGCGAGAAGAAGCCGCGGCTGGCTACTGCGAATTTGGGAT
TCGATTGGGAGGGACCGCTCACTCGGGGGAAATGGATTCTTTACCACGGCTGACCAGCG
257; SW vs I; chr20: 22505518-22507240; 20; FOXA2/C20orf56; DOWNSTREAM
CGTACCCGGCTCTCAAAGGCACGGCACCTTTGAATTAGGTTGCGGAGTGGCCTGGGCGAGGGGACCCGG
GGCCATCAAAGGCCCGAGGGAAGGCCGTGGGGCGACACCCGTCTAATGACAAGTAATTAAGGATTCGACG
CCGCGCATTACCAGCGGAACGGGAGGCATTAATTATTTAAAAACGATTAGCCTTGCCGTGTGTCCTGCAG
GCGTCCCATCATGTTCAGCGAAGATAACCAGCCACCCGAGGCGAGCCGGGGCTCGGAGGGCGGCGGGCG
CGCTCCCCAGCAGGCTTCGGGGCGGTGGACACGGGCGCACAGCCCAAGGCACCAGGGAAGGAGAGGAGG
GGCCACCAAGGGTCCCCACACAGGAAGGTGACTACATAACACTGACCCTGCTGAACAACGAAACAGATTT
CTGCCCACTTGGGTTCGAAGTCTGGTGACTGCGGCGCAGATGGGAAAAGCTTTCGGTCGGGGGTGGTGGG
CAATTTCCATGTGCCAGTTCCCTGTCGCATCAGACCAAAGACCCAAAGTAACCCAGCCAGGCACGGGCCT
CTCACAGTGCCTGCTACCCAGGCGTTTAAAGAAAAGACCCCAGAGAGAATGTGGATCTGGCGTGGGGGCA
GGGATTGGGGGGGGGCCTGGTAGACACCTGGGGAAATACAACTTTATGAGGTTTCAAGGGGCAGCAGCA
GAACTACTATTTTTCCGAGGTCCACGCCTTTCCGCAGGCGGCGGAAAGACGCGGCTGGTTCTGTTGGGTC
CTACAAACTCGCGTCCTCCGGAATTCCCGAGGGCAAGCCCGGCACGCGCAGCGTGCTCCTGCCCGTGGAA
GGGGGGAAATCGGCGACTGGGTTGCAGGGAGAATGCGATGATAAATGGCCCTGCGTCTGCTTTCTGACTT
TCTCTCCTGGACCCAGCTCGTAACCCCAGAGGCTCCCCAACCTGCCTGCCGCCAAGCACGGCTGTGCGCA
AAAGGCCACCACCGCTTCCTGCAGCCAGAGCTAAGGTTCACTCGCCTCTTAGAAAGGCGCGGCCCCTCCC
CTGCTGCTGCTTGATGACGATCCCCATCGTCTCCTCGGCCTGCCTGTGTCCGAGAAAGAGTTGAGACTGG
ACTCGAACCCCTGCGCGCCAAGGGGAGGGCGTCACCATGCTCCGCCTCAGCCTCTTCAAACTCCCATGCA
CCACGCACATCATTTTCTGCTGA
262; SW vs I; chr20: 54012011-54014085; 20; CBLN4; INSIDE
CGACGTCCAGGGACCAGGTGCCCTTCGGCTCCCGCCGACCTGTTGCTCGAAACTTGCCCTGAGCTCTCGC
TGCCGGGCTCTGGGCTCCCAAGCCTCTCCCCCGCCGCCGCAGCAGCCTCTTTTAGGGCCCGGAAGAAATG
GGAGCCGGGGCTGGTGAGAGGGGTAGGAAGAGGGACGGTAGAAGTTTCAGACCCAGGCATATTTGGGAA
GGCGAGTGCTTTACATGATTCCCCATTTCCCAATCGGACCAGCTTAGCCTGGGCAGGCAGCCTCGTGCTG
AGGTGCCTGGAGACCGCCCACCCCTAGGTGCTCGCTTCCCCCCGGGTCTGACCTGATCGAAGTAAATGAT
GCGCGTCTTGTTGCTCATCTCGGATGGCTCGTGGTTGGTGCTCCGCACCGCCGAGAAGGCGACCTTGGAG
TTGGCCGCCCGGACCGATATCCCCAGCGGGGAGGAAGAGGAGCCCTTGGAGTCGTGGCCGGGTTCGAGT
CGCACACCACCAGACACTTGCCCTCCAGCACGATGGGCTCCGTGTCGTTCTGTGCCCAGACGGGCAGCCC
CGGCAGCGTGAGGACCAGCAGCACGGCCGGCACCGCGGACAGCGCCCGGCGCCCGGAGCCCATGGTGAG
CCGTGTGGGCAGCCGCGCCGGCTGGCGCTGGTGCTCGCCCGCGTCGCCTCCTACCCCGGGATCCCGGTG
CTCGGGAAGATGCTAGCGGCTAGGTCGACAGCGCTGCAGGAGCGACGGCGGCGGCGGCGCGCACACTTC
CACCAATTCTGTGGCTTGAAGTCAAAGTCTCCCCTCGAGCTCTCTCGCTGCTCTGTTACCTTTGTCCTTTAA
GGAGCTCATGCAGCACCCTTTACCCTACTCTCCTCCGCCCAAGAATCAGCCCTGCCTGGGGCCCCTGCACC
CACTCTGGTTCCTAGACATCTGAAAGTCATCAAACCCTCACATTCACACCTCAAGGCAAAAAATAATAATA
ATAATAAATCTCACCCCAAACTCAAGCACCACCAGCTAAACCACGGAGCAGGAACAAAAAGAGGGGACTC
AAAGAGAAGCCACAAGGGTGGCGGGTGCCCAGCGGCGCGGGTGCCAGTCCTGTCTGGCTTGCGGCAGGG
ACGAGTTACAGAGGCAGAAGGTCCTTCCCAGGCTGAGAAGACGCGAGGCTGTGTTCATGGCCAGGACGCC
AGCGACTCCCACTTTCGCCTG
268; SW vs I; chr21: 33316999-33322115; 21; OLIG2; PROMOTER
CGGTGCCGGGAGCCTTGCCTCCCGCCGCCACCCCTGGTCAGCTCTGCGCAAGAACGTCGTTCTGTTTGGC
AGCCAGGCCGAGACGCAGCCTGAATGTGAGCAGGAACTCGGAGAAGGGAAGGGAGAGATCAGAAAGAAG
GCCCGGGAGGGACCCGGGAAGCAGTGGGAGGTCTGCGCCCTGGAGCCCCGCGAGAGCCCGCCGGTTTGG
CACGGGCTCCTCCCGGGCCGCCCGGCGGTCCAACAAAGGCCGGCCCCGACACGCACCCGGTCTTTTGTGG
GAGAGAAACACAAAGAAGAGGAAAAACACGGAGGAGGCCAACAGCACCAGGACGCGGGGGCCAACCAGG
AACTCCCGGAGCCGGGGCCCATTAGCCTCTGCAAATGAGCACTCCATTCCCCAGGAAGGGGCCCCAGCTG
CGCGCGCTGGTGGGAACCGCAGTGCCTGGGACCCGCCCAGGTCGCCCACCCCGGCGCCGGGCGCAGGAC
CCGGACAAGTCCTGGGGACGCCTCCAGGACGCACCAGGGCAAGCTTGGGCACCGGGATCTAATTTCTAGT
TATTCCTGGGACGGGGTGGGGAGGCATAGGAGACACACCGAGAGGTACTCAGCATCCGATTGGCACCAG
GGCCAAGGGAGCCCAGGGCGACACAGACCTCCCCGACCTCCCAAGCTACTCCGGCGACGGGAGGATGTT
GAGGGAAGCCTGCCAGGTGAAGAAGGGGCCAGCAGCAGCACAGAGCTTCCGACTTTGCCTTCCAGGCTCT
AGACTCGCGCCATGCCAAGACGGGCCCCTCGACTTTCACCCCTGACTCCCACTCCAGCCACTGGACCGAG
CGCGCAAAGAACCTGAGACCGCTTGCTCTCACCGCCGCAAGTCGGTCGCAGGACAGACACCAGTGGGCAG
CAACAAAAAAAGAAACCGGGTTCCGGGACACGTGCCGGCGGCTGGACTAACCTCAGCGGCTGCAACCAAG
GAGCGCGCACGTTCGCCTGCTGGTGTTTATTAGCTACACTGGCAGGCGCACAACTCCGCGCCCCGACTGG
TGGCCCCACAGCGCGCACCACACATGGCCTCGCTGCTGTTGGCGGGGTAGGCCCGAAGGAGGCATCTACA
AATGCCCGAGCCCTTTCTGATCCCCACCCCCCCGCTCCCTGCGTCTCCGAGTGACAGATTCTACTAATTGA
ACGGTTATGGGTCATCCTTGTAAC
276; SW vs I; chr3: 148591199-148594390; 3; ZIC4; INSIDE
GGCCGGCCGGCCTTCCTTCCTTCCGCCCTCGCCCTCTTCATGCCTCAGAAACGTGGCCTACTCTGCATTCG
GTGTGTGCGGAAGCAGCAATCACAGAGGCAGCCCTAATACCGGAGGCGGCGGCGGCGCAGCAGGGCCAG
GTGGTAGCTCGGGGCTGAGGATCGCGGCGGGGGCAGCCGCTATGGGGCCCAAGCCCTGACACACGTACC
ATTCGCTCAAGTCGGCGGTACGCGCCGCCACCGCCGCCGAGGAGGCCACCTGGGACTTGTGGCCGCAGTC
CGACGAGGGCGACACGAGGGAGACGGTGTAGCCGAATCGTAGCCAGAGCTGGGCGGCGGCGAGCGCCCG
TGCACCTTCATGTGCTTACGCAGCGAGCTGGGGTGCGTGTAGCACTTGTCGCAGCCCCGCACCTTGCACG
TGTATGGCTTGTCGCTAGTGTGCACGTGCGAATGCTTCTTACGGTCGCTGCTGTGGCGAAGCGCCGCTCG
CAGCCCTCGAACTCGCATCTGAAGGGCTTCTCGCCTGGCGGAGGCAACGCAGAGACATTAGTGCTTGTGG
GTCGTGTTCCCGTCAGGTGCTTGCCACCCTCCCCCATTCGTCTCTCATTTTCTGGAAAAGAACTACAAAAT
ATTTTCAGAAATCCTTTCCACGGCGCCTCAGGTCGAGCACCCCTTTCCCTCGTGCAGAGAGCGCCCCCGGT
GCCCTCTCTTGAACGCCTCCATCCCTCCCGCCTTCCTCCTCTGGGCTCATGGGGAGGGTATGGAGGAGGA
GCGACAGTGACTCCATCTTAGTCGAGTTTCCATCCTCGAAAATCCGATCCACTCGGGTTGTTTCCTCCAAA
TTTTCTCCACTTGGAACCAGAAGCACCTCTGCTCGGAAATACATTAACGGAGGAGCTCACAATATAGTTAA
CGGGGAAGCTCACATCTGCTCGATTTAAAGTTGCTGTTTCAGACTAACTTCTCTGCCGCTACCCCGCCCAG
CCGTCATCCCCCCCACCCACCCCCATCCTGGCCCAAATTGTTTCCTAAAGTAGGTTTTGCGCAAACGCCAA
AGCGATGAAATAATTTAAGGATGCGCAGCCGATGCACATTGTGTGTGCATAAAGTGGATTCGTGCTGCAG
GGAGAGGTATTCTGAGCAATGATTCACTTCAGAAGGATTTTTACAGGAATGGAGCCCCCTCCCTCTTTCCT
TCTACCCCCTGAGG
285; SW vs I; chr4: 122520930-122521740; 4; GPR103; INSIDE
GAAATGTTCTGGAGCATGGTGACGGGAATGCAGAAGAAGGTGATGAGCAGGTCACTGAGCGCCAAGGAG
CAGATAAAGATGTTGGTGACGGTGCGCATGGCCTTGCTGCGGGTCACCACGTAGAACACAGAGCATTGCC
AAAGAGCGCCAGGGCGAAGATGAGCACGCCGGTGAGCACGAGGGCCAGCTTGGCGCGTCCCGGCAGCTC
TGGGGTGTAGACGAGCGGTCGCAGCCGGTACAGAGCGATGAACTGCTCCCGCGTCAGGTTGTGGTCCCGC
AGCAGCCGAGAGAACTGCTCCGGGTAATGTTAAGCGCCTGCATTGCTGTGCGCTCCCGGGACGCGGGGCC
ACCGCCCGCTACTGGCTGGCCATCCGCATCTGCGGGGCAGCGAGGGCTTCGGGGGACCAGCCGGAGGCC
GCCTCCCTTCCTCTACTCTGGAGTCAGCCGCGCGGGAGGGCTCTAGGCTGCACCCGGGAGGTTCGGGAAA
GGAGAGCAGCTCAGGGATCAAACCCACGATAAAGAGGCGGGAAGCCAAAGCACTGGGAGACTCGATCTC
AGTGACCAAAAAATGTTCGCGGTTCAAATAAAGTTCTTCCCTTGCTCTTCCCTAAGGCGAGGCGCCGCCAC
GGTCTGGGGTGCTGGACGCCACGCGAGGGTCCTGGCGCCTCTGGCTCCCCGCCTTCTGGCCATGCGATGC
GGACGCCGGACCCGCTTGGGGAGCGGTGGAGGGTGGGGCTGAACTCGGTGACGCCTCCCTCACACCCAG
CTTCAGTGGCGCCAACGCCGCTTCCCCGCACCCTCAGGGCG
293; SW vs I; chr4: 155881084-155881434; 4; LRAT; PROMOTER
GAAGATGAGGTGCAGAAGTAAGCTGGGACCTGTGAGCCTCAATTTCGGCCTCTTCTGCGCTGAGACCCAA
GCGGATCTTGCTTGGCCTGTATGCGTTACTGGGGGAAATGGACGTGGGCCTGAGCGCGCAGGTGCGAGG
GCGCTGCCCCGGGGCCGACCACCCTGCGGGGACACTGTAGCTGTCATTCCTTCTTCTGCAGGCGGGTAGG
GGAAGCGGTGGCCAAAGTGGGAGTCGACCGCTCAGCACAGTCTGTCTGAGTGTTGACCAGGAAAGTCCAG
GCTCTTTCTAAATCTCGCCGCAGACCTGGTGACGCATTCGCATGTATTTAAGGCGTTTGCACGCAGAACG
296; SW vs I; chr4: 177159356-177159814; 4; GPM6A; INSIDE
CTTTACTCTTGGAGAAATCCCTCACAACAAAGGACAAGGGAGAAGCAAGGGGGAGGGGCGCCCAGTGGAC
TTGGCTGGAAGAAGTGAGCGGGCTGGGGTTGGAAGAGTAACTCGGGCTGCGGGCTGACGCAGTCGGCAA
CCGCGGAAGAGCAGCATCTCCCCTGCGCCTGTGGATACGCCAGTCCAGGGATGGCGAGTGCTTTCTCCTC
CCCAGCTTCTCCCTCGCTCTTCGAGGTGACTCGTGGGACCCTGCGTCCTAGTGCTGGGTGTGAATCGGCT
ATTTCACACCCAGTTCTTCCCCCCTCCGCCACACGCAGTCACATTCCTGGAGCTATTCCAAGCTGCCTCCG
CTAAGCACCGAATAAGCGGACCCTGCCTGGAAACTTGAGCGAAGCTGAACTGCGCCGAACTCCACCGTCC
AGTGACCCGAGCCAGTGTGGACGCCCTTTTAATCACG
317; SW vs I; chr5: 140724146-140724826; 5; PCDHGA5; INSIDE
CGCTGTGCGAGCCAGGATCCGGGCAGATCCGCTACTCGATGCCGGAGGAGCTGGACAAAGGCTCCTTCGT
CGGCAACATAGCCAAGGACCTTGGGCTGGAGCCCCAGGAGCTGGCGGAGCGCGGAGTCGCATCGTCTCC
AGAGGTAGGACGCAGCTTTTTGCCCTGAACCCGCGAAGCGGCAGCTTGGTCACCGCGGGCAGGATAGACC
GGGAGGAGCTCTGCGCTCAGAGCCCACTGTGTGTGGTGAACTTTAACATCTTGGTTGAGAACAAAATGAA
AATTTATGGAGTAGAAGTAGAATAATCGATATTAATGATAACTTCCCGCGTTTCCGGGATGAAGAGTTAAA
AGTAAAAGTTAATGAAAATGCGGCTGCAGGGACACGGTTAGTGCTTCCCTTCGCGCGGGATGCGGATGTG
GGTGTGAACTCTCTCCGGAGTTACCAGCTCAGCTCCAATCTGCACTTCTCTTGGATGTGGTAAGCGGAACT
GATGGACAAAAGTATCCGGAGCTGGTGTTGGAACAGCCCCTAGACCGCGAGAAAGAGACTGTTCACGACC
TCCTCCTCACAGCTTTAGATGGCGGAGACCCGGTACTCTCCGGCACCACGCACATCCGTGTTACGGTCCTC
GACGCAAACGAAATGCGCCCCTGTTCACCCCATCCGAGTACAGCG
333; SW vs I; chr6: 101023927-101024343; 6; SIM1; PROMOTER
CGAATCGGGAATTGGCATTCCGTAAGGGAGCGGAGGGCCTCAGGCCACTAGGCAGCTCCGAACGCGGGG
AAGCGGGAGCAAAGATGAGCTCAGAGCGAGGGTTGCCGGCGCCACCCTGGGCTGCGCATGAGGGGCCGT
GGACCCGCCCCGAGACTCAGTGACAGTCGCAGCTTAACCCCGTTGGGGGCGCCGCCCCGCTGAGGTGGTT
GCGTCTCCAAGTCGTGAGCCTCCAATAGCTGCTCCCGCTTTCGCGTCGCAACCCCAGGACCCCGGGAAAT
TACCACTGTGCTCGTCTGGGCGGAGACCCGGTGCTTCGGAAGCCTGGGGCACATGCCTGGGTCCCACCCT
AGACTCACCGCCTCTGGGCCCGAGACATGGGAATCTGCCCTTGAATATCTGGGCGCCTTTGCTGTTA
367; SW vs I; chr7: 121727243-121727884; 7; FEZF1; DOWNSTREAM
CGCTCCACAACCCGGAAGGAGCTCAGGCCGGACTTGGCGTGAGGGTCCCTGCGGGGCTGGGTCACCTAC
CCGTCCGCGATCACCCCACAGGGGCTGTTAGTAATCTCCCTGCTTCCTAGGCCGTTGAAAGCACTCAGGTC
ACCCACTCTCGGTGACCAGAGCGGTCAGTCTTTCCCCGCCATGAAATGTGAGTTCGGGTGGCAGCCGCCG
CGCCCCTGCAGTGTCCCCTGCACATCTCCGGTCTCGGTCTCGCCTTTCTCAGCTCCGCGCCGCCTTTTCCT
GGGCGCCGCAGGACTCATGAAGTGAGGCGGGGCCACAGATTTAAGTTTATTCCCCGCAACTGTCGGGGCG
GTCCCGGAGCTGGTGAGGACGCGCTACGGTGGGTGCAGAAAGGAGATCCCTGGACTCTGTAGAACCTGG
GCCCGCGGTGTGGACCGATGGTGGATTCTCCGCGACAACAGCCCTGGAGGGGAGAGTGGGCCGGGGGAG
GGGCCACGGGGCCCCTGAGGCCTGCGGGGCTGGCCGCACTGGCCCCGGGCCTGGCGGGGTGGTGGAGTC
CGAAGCGGCGAGGCGAGGACCCCGGGGCCCGCTCCCCCCAGTCGCCCTCCCGGGATGTGGCCCCGCTGC
AGTAGCACTACG
376; SW vs I; chr8: 9798161-9799053; 8; hsa-mir-124a-1; PROMOTER
CGGGCTCCGGTGCGGGACAGGCAGCCGGAGGGAGCTCCAGACCCCTCCCCTCGCGCCCGCGGCCGCTGC
GCGGAGGTCTGCGGAGGGCGCCTGGCTCGGTCGGTCGCTCCTTCCTTGGCGGGCCCTCCCGACCCACGGT
GCTCAGCCAGCCCCATTCTTGGCATTCACCGCGTGCCTTAATTGTATGGACATTTAAATCAAGGTCCGCTG
TGAACACGGAGAGAGAGGCCTTTCTCCTGAGGAAGGAAAGGAGGAAGGAAGGAAGGAAAGGTGAAAGAA
AGGAAGAGGGGTGGGTAGAAATGGAATAAGAAAACCAGGAAAAAGAAATAAAAAGCGGCGCGTGTGCGT
GCGCACTGACAGCGGGGAGAGGGATGGGGGTGGGGAACGCCGGAGGAAGGGACCACAGCATCCTCCCCG
CCGCAGCTCCCCCAATCACACAGACAATGAGATAACAGCGACGTCTTCCAAAGGTCTTTGTTCTCCCCCAT
CCTTTCGCATCCAGGCTTTTTCCTGCAAAGCGGAGGGGGTGGAGGGATGGGGGTGTGGGTGGAAGTGGG
AGACGGAGGGGTGCCTCCCCCGTGTTAATTACCCCGGCTCCCCTCGCCCCTTTCCCCGCGCCTCGCCTCC
CCTGCAGCTCCAGACATGAAAAAACAACATCGACCCCACCTCGCCCCAGCGCAGCAACCCACCCACCCAT
GTCGCCCTCTGCTTCGCCCAGGAAACTGAAGGGGACTAGGAGGAGGAAGAAGAGAGCGAAGGACAAGGA
GAGCAGCGGGGACTCGGCAGCGGCAGCCGGGGCAGGGCGCGCGGCCGCCCCTCTTTACCTCCATCGCTG
AGTGGGGGCGCAGCCGGGCCGGGCGTGCCGCAGGGGCGAGTTGCCGCGGTCCG
380; SW vs I; chr8: 65661156-65662687; 8; BHLHB5; DOWNSTREAM
CGCGCGCGCGCGCACCCGCACGCAGTCTGCAATGCCCTCACCAGTCCCCGCAGCTGGGCAACCCCTCCAA
GACCCTGTGTTACGCTTAAATTCCTCTCCCTCCTATCGTACCCACCATCCATCCTTAAGCAGGGAGGCCGA
GACTCACAGAATTCCCTTCTCCACCAACTCGCACTCTTGGTCTAGCACGCGGAAACCGAACCTTTCTACGC
GGCCCGACCTTGCGATTGCTCCAGCATGAGTGGCATTGACTTTTCCAATGTAATGACTTATGAAAGATATA
ATCATGTGTTAAATTGATCCTCCGTTTAACTGTTAATGGTGTGCTCTGGGCACATTTACGTATTTGATGCTA
TGGTAACTAATTACCACTAGAAAAAAGGATAATACACTTCCCAGACTTTGAAAAATAATCATGAGTTCACT
TCCCGGCTCGCAGCACATCGTGGCGGCCCTGCCGGGAGGAGCGAGAAACGAGTGGAAACCCGAAAGTGT
GCTCATGGAATGCAGGAGGTAATGAATCCTGGTCAGGTGAGACTACTTAGTCAAACCTTTAATGAAAACGT
GATTCACATGGAAAGCAGGAGTGGGAGGGAACAACTACACAAAGGTGCCTTTAAACAAAATTAAATGGCA
AAACCTGCTATCAGAAACATGAATAGGTTTCTTTCAATTAAAATGCAGGTAAGACTAAATTATCCACGTGC
CAAGCAACTTTACATCAATTAACATTTTTTTGTTGTGTGGGCAAAGTAAATGAGCCCGGCTCCTGTGCTCT
CTGTATTGGCATATACAACTTGAAAGTCTCTGGATTTCCAAGCCAATGAGCTGCAGGTTTATTTAAATTCG
GCCTTTTAAATCAAACTTTAGACACAGTAGGTGGAAGGAGGGAAAGAGAAGGAAAAACAAGGAGTCAGTA
ACTTCAGTTTAACAGTAGAAACAACTCTTACGGTGAGAGTCTTTTTTGCCCGGCAAATCTCTGGCTCTCTG
ATCGACTGGTGTTTAGAACCAAGGTTCCAGTAAACAGGGCTGGGTAGGATAACGAGGAGAGTGTTTGTGC
TGGGACCTGGCAGGACTGGAGGAGGAAAGGAGCCGCCTTCCAGCAGGTCCAGCATCCCTAGGTTGCAAAC
ACACCAAATGACGTCCACGCAGCACTCGCCCCACCGCGCTGTTTTTGCTTGCGCAGTGCTCCCGAAGGGA
TTCGGGATC
398; SW vs I; chr9: 121170908-121172141; 9; DBC1; PROMOTER
CGTCGGGAGCGCGCGGGGACACACACGCCACTCACTCAAACCCGCAATTAGCCCTTTGAGCCCCAGGCAC
AGGAACCCCCTCCCTAGAACTGGAGAAGACTTGGAGGCGGCGGGGCGGCCAGGTGAAAGCGGACAAGGG
TGCCGGTAGGGGGAGGGGCAGAGGAGCGCGGGGACGCCCCGAATGCGGCCCGGGGCCGGGTCCAAGGG
CAGCGGGGCTGCGGGGCGCTGCACCCGGCGCCGCCTTACCTGGAGTCAATGTCCGTCTTTGGCGGAGAG
CTGCGGGAGGACGCTTTTTATTCGCTCGGTGGGAACTTGGGAGAGCCCTGCGTGCAGCTCGCATTCCGGG
CACGGCGCGGGGACTGCAGGCGTGGGGGTACCTGGCTCCTAGCAGCCTGGCTCATACTCAGCCGTAAAGT
CCCCTTCGCTGGTCCCGAGGACAGGCATGAATCCCGGCTCCGGAAGGCGGTCACTCTCCCTCTGCCTCCC
GGCTCTCTCGCTCTCGCTCTCGCTGTTGCTCGCTCGCTCTCTCCCTCTCTCGCGGGTTCGCTCGCCTGCGC
TCTCCTCCTCCCCGCGCGCCAGATCAGTTTGCAGCCGTGGGGTCCGGGAGCGAGGCGGCTGGCGAATGGA
GAGGGAAGTCCAAGTGGCCGCGGTCTCCGGGCGGGGAGCGGCGGAGGCCGGGCTACGCCGGGGGAGGG
ACTTAGCCGGCGACGGCCGAAAATGAATGGGGGAGCGGCGGCCGGGGGGCGGGGAGGGAGGAGCTGAA
CGCCGGGGTTGCTTCCGAGGAGTGTTTTGTACATCTTTAGGCGGAGGAGGAGAGAAGCGAGAGGAGGAG
AGACGGGAGGCCGCCTCGAGGGAAGGGCGGCCCGGGTGGGCTGGGGCTGAGCCGTAGGGAGTTTCGTGG
GTCTGGGGCGTGTAGGGTGTTGTGTCTATGCGCACGAGCATCCAAAGGGACCGCGCATACGCGCAAACCC
GGAATCCTGGTGCCCTAAGCGTGACTGTACTGTGTGTGTCGCGAGTACCTGAGTGTTTCTGGGGCGGCAG
GTGTTTCCACGGCCGCGTGGATCCATCGAGTGTGGGTTTTGTCTCGGGAGTTGCCCGTGTGGGTCCGTTT
GTGTCTGCGCGTCTCTCTGTGAGTGTTTGACACTGTTTGTTTCTCTCGTGTGTAGGCGAGAGCCCACGTAA
CCTCCCAGAATGAAGCAAGAGCTTCTC
403; SW vs I; chrX: 50040955-50041296; X; CCNB3; PROMOTER
GCGTGTCGCAGCTGTGCACGCTGATTGGTCCTCTGCTGGCCAATCACCACTGCACTTCATGACGGCTGTA
GTTTTCAAAATCCCAACTGGGCTGGTGGAGGGTCGCAGGTGTCAGGTTGAGACGGACCGAGTCGCTATAG
TAAGGAGCTCCGTTCATTTCCTTGGCCTCTCCTGGTCTAGGGGTGCGTCGATGGTCTTTGCTGTCTGTCCT
CGATCTCGGTGTGAGGTAGGCGCCTTTGGGCAAGTACTGCTGGCTCCAGCGTCCGGCTCTGTCGCCTGCC
AGTGGGTCCTTGGGCGTCCTCCAGCCCCTTGCTGAATTCTGTTGCTGGGATGCGCGGCG
TABLE 3
CpG islands hypermethylated in (bladder) cancer. Provided
for each are: ID; Comparision; Coordinates of selected regions containing
relevant CpG islands based on Homo sapiens full genome as provided by
UCSC (hg18, March 2006); Chromosome; GeneName; Location relative to gene
Sequence.
2; ALL;; chr1: 2072175-2072389; 1; PRKCZ; INSIDE
CGGGCGCGGGAGCTACGCCAAGGTTCTCCTGGTGCGGTTGAAGAAGAATGACCAAATTTACGCCATGAAA
GTGGTGAAGAAAGAGCTGGTGCATGATGACGAGGTAGGTGCCGCTTCTCATGGGGCCGGGGGCCCGGGA
ACGCGCTGCCCTGGGGCCTCCTCCGGGCTTTAGCGGAATTAATCCATGCACGAGAGACCTAGCCTCACGT
TGACG
3; ALL; chr1: 2106293-2106715; 1; PRKCZ/FP7162; INSIDE
CGAGGAGTCGGTGTGAGGCCGCGTGCGTCTCTGTCGTGGACACGCGTGATTGACCCTTTAACTGTATCCT
TAACCACCGCATATGCATGCCAGGCTGGGCACGGCTCCGAGGGCGGCCAGGGACAGAGCTTGCGCCGAG
ACCGCAGAGGGAAGCGTCAGCGGGCGCTGCTGGGAGCAGAACAGTCCCTCACACCTGGGCCCGGGCAGG
CCAGCTTCGTGCTGGAGGAACTTGCTGCTGTGCCTGCGTCGCGGCGGATCCGCGGGACCCTGCCGAGGG
GGCTGTCATGCGGTTTCCAAGGTGCACATTTTCCACGGAAACAGAACTCGATGCACTGACCTGCTCCGCCA
GGAAAGTGAGCGTGTAGCGTCCTGAGGAATAAAATGTTCCGATGATGTGGAGCTCCTCTGATGCCTTTTTTC
6; ALL; chr1: 33385564-33385979; 1; chr1: 033385935-033385979; Unknown
CGGACGTTAAGCCGCGTCCAGGGCTCCGTGCAGGCGCTGTACTGGTTGCCATCGTGCATCACGATGCAGT
AGAAGCCGCGGCTGGGCTGGATCTGGATGCTGCCCTTGCGGCTTGCGGCTTCGTGTGCAGCCCGATCACC
CACTGGGTCTTCTCCGCCACCACCACCTCCCAGTAGTGGACGCCACTACTGAAGGCTTCAGAACCCAGCA
CCGACACCTCCACATCGAAGCGCTTTGGCGAGTCCTGCAGTGGCTGTGGGTGCAGTTGCCGTAAGCCACA
ATGGTGCAGTCGTCCGACAGGATCAGGCGCTGGTGGGCTGTGCCCGGGTCCAGGGTTAGGGCGGCTGGC
ACTGTGGGGGTTGGAGGAGGGAGAGAAGATGAGTGGGGAGAAGGCTGTGGCCCACCATGCAGTG
8; ALL; chr1: 47672249-47672972; 1; FOXD2/MGC12982; PROMOTER
CGCGCCGGCTTTGCCGCTTTCCCTGAGGGTGTCCAGTTTTGTGAATAAAATTAGAGAAATCTGCGGGCGTA
GTTCCCCAAGCCCAGCTCAGGCTTCCGTTTGCAGCCCGGCGCTGGCCGAGCTCGAACGCTGAAAAGGGCC
GCGTGCAATCGTTCCGCTGTGCCTCAGGACAAACTCCGCTTCAAGCCAGTGCCGCTCTCCGGCAGTTTCCT
GATTGACTTAATTAGATCCGCATAATCGCTGGAGGGCTTTTCTTTCCCAGACCGAGAACAGCTCATTTATG
GGGACCAAAAGGAAGAGAGGGAGAGACGACCCGGACGCCACTGATAGCAACGTACTCTTCGCAAAAAACA
CTCAGTAACTAGTGGAAAAGCCCAACAGGCATCCCCCTCCGCCCGCAACGCTTCCTCCCAATTGTTCTGGG
CTGCACGAGGGAGATGGCCGGGCCGTGGAACAGATGCAGAAGGAGGCCCGGCACGACCAGAGACGCTGT
AACCAAGACCCGCAGAGCCTGTGGCTTCCCGCTCTTTGGCGGTGCAGCAGGCATGGTGCTGGAGCCCAAG
GCTTCTGGGAAAGAGTCCAGGTTTTCGCGGAGGGAGCGACGGACTCACGCGGGATCGCAGGCACTGCTG
CAAGACGCCGAACAGGCTGAGCCGGTAGGCGAAAGAAGTAGGGTCACAGAAGAAGCAAAGAAAACGAAA
TAAATTCCGAATCCCGCG
50; ALL; chr10: 21828640-21829645; 10; C10orf114; PROMOTER
CGTCCGGGAGCCTCCGCAACTCGCATTTCCCAGTCGCAACCCTGGGTCATTCCTGCCTCCGTCCCAGCTCC
CGGACAATTCCCAAAGCCAAAGGCGTCGAGCGTGTTACTGGCTCCCACCAGCCCAATTAATAATCAGCTTA
ACTCGTGGAGGCTTTGAGCCCCAGTGCTCCGTTCCCTGAAGCCTCCCAGTGCGGAGCCCGGCTCCTGCGA
GGACATCCTTGGAGGGGGGCCGGGGCGCAGGGACGGATTTCCTGGGAAAAATGTCGCTGGCGTGTTGCA
CCTAGAGGGCTGTGGGCAAGGAGGCACGCACCAATGTCCCAGTTCTGGGCTCTCAGATCGGGATTCCTCC
AAAATCGCGACAGCCGCTCAGGTGCTGGGTGCTCACGTTGGCAGCACAAGCGCCAAATGCACGACCCCGC
GCGCCGCGCGCGACCTCCACGCACACTTAGAGCCGAGGTGACAAGGGAAGGCGGCGGGGGTGGAGCCGC
TCTCTGGTGGAGCATGATCAATCACTTTAAAGGGTTCAAAAGTTCAAGTTCCCCTTTGGAGGGGAGAGGTA
ATGCTTCCCGCGGCCTGCTTCTCTCTGAGACCCGCGGGTTCCCGGCAGCCGCGCAACCACTGGGGATCTC
GGCTGCCGCTTGCGGGAGCCCCTTCCGGGGAACACGCTCTCGGGCCGCGCAGCCGGGCGAGGTTGACGC
AGCTGCTAGGGGGCAGTTTGGCTTCCCCGGGAGTACCGGAGTCGCTCGGCAAAAACGTGATCTCAGCCTG
CAGGGCCCGGGGCGCGCGCTTTTCCCTTTCTCAGCAACGGGAAAGGCCTGTTGGCAGAGGCCGGCGGAG
TGCTGGCGGCCTGGCGGCTGGAGGCTTCGGCGGAAACCTGAGCTCCCTGCGACCTGTTCTGCTAGCAGGG
GCGGGGGAGAGCCCCAATAAGCCGCCCCAGAGGCGACCGTGCAAATTCCTAAGAAAAAGCCCTCTAGAAA
ACACCAAGCCCTTCCAAAAG
54; ALL; chr10: 22804715-22807056; 10; chr10: 022806090-022806137; Unknown
CGTCGGCGCTAAGCAGCTCTGGAAACGGGCAGACCCAGCTGTGCAGCGATGTCCAGTGTCGCCGCATCTG
CCCCGCGGGGTGCAGCATGAGTCTTCCTTTGTGGCGTGCGGCTCCATCGGAACGCGCTTGCGACGACAAA
TTCCTTTTTTCCCCCCCGCAGTTAACAGTTCTGGGGCAGAGGCTGGTGGAGAGGTCCAGAGCCCACTCAG
ACCGAGATGAAGATGAGGAAAAGCATGAGCAGGAAGAGGCTGGCGGCTGCGGCGCCACAGGGAAGAGCT
CGGTGCGCGGCGCAGCCTCCCGCGACCGCGACTCCTGGGCTGCGTCGAGGAGCCGCGTTGCCATAGGAA
CCGTAGCGGCGCCCCAGTGAAACCCTGCGTTCGGACAGGAGAAGCTAACCGGGCCGCCCACTCCCACCCG
CGCTTCCTCCCCGCCCCCACCGGCCGTGCGCGAAAAGCAGAGATCCGAGAACCGCGTGCGGTACAAACGG
CAAAAGCTTCGCGCGCATTTTCCGGGAGTTGAGCGCGCGGCCGCAGGCGGGAACCTACCGCTCTCAGGCT
CCCAGCCCGGGCGCTACGACCCTGTGGGCGCCGCCTGTGCAGCCCCTCCTTCCAGCCCGCTCGGGCGCAT
CCCCCAGGCCGGGCCAGCGACGCGGGCACCGGGAGCCCCTCCCCCGGTCCGGGCTTTGGCCCACACCCG
GGGACCGCGGAGTGGGAAAGGAACCAAAGCGCGGCGCCTGGCCGACCGCGGACGAAATTCGAGGCCGGA
GGGCGTTTTCTTTTTTGCAAAATTGCCCCAAAGCCAGGGCCCATGTACCTACTGTCTCCTTTGCCCCACAT
GCTCCAAGAAAATAAGACACATTCTACCCCGAGTCCTAATTATTGGGCCATTTCCTTAACGCGCGGTCTGT
CCCCGTGGGCAGAAACATACTGCGAGATGCAGTTTGGTAATTAACAAAGAGACGAGACCTAACTGGGCTT
CCGAAATGCTGGATACTGCGGCCGGGTCGCCCCGCATTCGGGCATCGCGCGGTTCCCGGCCTTCGGGACG
TTCCGGCCCGGCCGGACTTTGACCGCTGGCGAATTAGGAGAAACGCAGAAGGCGGACGCTCCCCAATTTC
CCCATCGAGCCTTCTCCTCCCGAGTCTGCGAAGCCCCTGGCTCAGGAGACACCGGCTCCGCGCCTGGGCC
TGCAAATCCGCTTCCAGCGAGCGCAGGCCTGTCGCTCC
87; ALL; chr12: 94776044-94776377; 12; SNRPF; PROMOTER
GTTACTTCCCAAAGGGCGTGTTCTCCAAGAACTGCATTTAGCATTTCAGATCAGAGTGACCCGAACTCAAT
AGGATTACGACAAAAACTAGTGAGATTCAGATAACACCGTTACATCGAAAGTTTTATCCGTGACAGAGGAA
ATATTGCTTACGCCCTTAGGTAATTTCAAATGCACGTATGAAGGCCGTGCGGGTTTCTGCAGGCGAAGCAA
AAGAAAGGTGGGGCCGGCAGGGTCGTGGGGCGGGGGTGGGGCATGACACCTATCCCAGACGCAACTCGA
CCTCGTTTGCAAGAAATTCTGTATCCAACTCTCTTCAGTGCGTTTCGCCG
94; ALL; chr12: 113657930-113659205; 12; chr12: 113657930-113657987; Unknown
GTTCAGTGGTTTATAGAAAATTTCTTTCTCTCTCTCAGGTCCACTAAGACCGAGAGAGAGAGAGAAGTCGA
CTCTGGCACACCCGGGCGAGGGGCTGCCGGGATTCGGGAGCTGGCGCGGTTGATTTTTCCGAGAATCCTC
CACTTGGGGTGACGTCGGGCAGCGCGCGCGGGCCGTGAGGTTAATGCCCAGGCTTTTCTCTAAAGCGTCC
GGGAATGATCCGGCGAATAAAACGGGTGTCTGCAAAGTTAATGAATTGTACAGGAGGCTGAGGGTGGGGA
CTTCGACCCGGGGAGCCAGAGGCGGTTCTGGTGGACGCTTCCCCGTGCGCCTAGGGGTGCGCTGGGCTTT
CCCAGCCGAGGTCTGCAGAGCGCACCGCGTGAGCTTCATCGATCTCATCTTCTTCCAAGTGGGAGGAGGT
GGAGATGCTGGGAGAGTTGTGGGGAGTTGGGAGTGGGTTGGAGGGGGACTGTCTAGATTCTACTCTGGA
GGATCCAATCACGTGGTGCTGTTCCCCTGCCTAGAACTTCAAGGTTTCCAACGGTTTGAATAAAACCCAAA
CGATGCCCGATGTCCAACGAACGAATGATCTAGCCTCGGCCTACTTCTCAGGACTTAGCTTTGTCCCTGCC
CGCGACTTCCCGCTGGGAACGTCGTCCCCGCCACCACCGCTCTGCTTAGGTTCGAACTCTGGGCCACTCTT
CCTACTCCCTCTGGTTTCCAGCAGGAGAAGCGCTTCGGAGGAGGGGGCTAGGGGCGCTCAACCTCCCGGG
TTAGAGGAAATGCAAGTTGGGCCAATTTCGCCCTCCAGACTCCGAGGCGGATAGGCCCAGGGGGCAGCGG
CCTTGCCCGGCGGCCACTGCCCTCCTCCTCCCCCGCGCCCCCTGGCTAGGCTTTGAAGAGCTCATTTTAAG
AACTTTTCCATTTTCCTTTTGGAGGCGTGTTGTTCTTCTCAGTCACCTCGCTTTTTTTTTTTTTATGAGCTTC
AGCGCTGATCTGCACGTTCTTCCCTCCGTGTAATTTCAATTTGAACTCTCCCCAGAGCGGCCTTTTCCCTCT
TGTTGCCTGCCAAGTCGTTTAAGGCTAAGCAAACATTCTTCCTCCCTCCCGTCCGCGCGAGTCTCGGTCTA
CACCCGCGAGGGGAGGCGGAGGCGGTTACTCCGAGAGTTCCGGTGGGTTGGAGCCTTTCAGCAGCCGCC
TTCAGACTGTTTGGGAGCCGAAAAGCG
99; ALL; chr13: 34950488-34951119; 13; MAB21L1; PROMOTER
CTTTGCCGTCATCGCGGGTGAATGCACCACTACCTTTTGGCAGTTGGAGGGGAGACCCATCAGAGCCGGA
GAACCTGCAGCCACGACGGCGAGGATGTGCAGTGGTCTCTGGGGAAACGCCGCCTTCGCCCTCACCCGGC
GCGTGTGGCCCTGTGCCGTCCGCTCGCCGCCTCTCTCTCGCTGCTCCGCATTCCCGTGCCCTCTTACTTTC
CTCTCTGGGCTCAAGATCGCTACGCTTTATTTCTGCGTGAGCTTATTTGAAACCTTACTTGGTGTCCCGGC
TTACTCTCCACGTCTGCTCCAGACCACGGTCTGCCCACGCACCCCTCAGCCTGCACCGCCCACGTCCGGCC
CAGGTGTGGTCGCAGCCAAGCCCCAGCCGCGGGCCCCTGCGCCCTGGCTCTCTCCCTTGGGTTCAGGCCA
GAGATGCTTGCCCCAAGACCTCGCCCCTTGCCTTCTTGGGCCACCTGCAGAACACCCTTGGTTGTCAAGGA
CGTGAGACAGCCGAGGACGGGGAGGCCCCAGGGCTGTTCGGGGACCTTAAGTGGGTCCAACGGGAAGGA
CGCGGGCCTGCGAGGGATGCCGGTCGGGCCTGGCTGGAGCCAGGCGCGCAGGTGGCGCATCTTCG
102; ALL; chr13: 49595986-49600287; 13; chr13: 049599159-049599206; Unknown
CGGGCGGACGAATGGACGGATTCGAGCGAAGCTTATTTCCCTTCTCCTAACGCATCTACCTATAAATAGCG
CTCACCGCGCTGAGTCACCAAAACCCCGAGTTTCCCCAAATAGCGCGTAACGACTGTGGGATCGCGTCCC
TCGGGGCTCTGTGACAGACTCCAACCACACACCCGCTGGGCTGGACTGCGGGCCCACACGGCCCAGCGG
GTCTCTCACCACCCGGCGCCCCAGGGACGCGGGCGAGGCCGCGGTGTCCGGACGAGTCGACAGCGTCGG
ACTTCCCGCGCGCGGACGGCGCTCTGGGGAAGGAGGAGCCGGCGGGCGGCTGGACCTGGCCTTGACTGC
GCGGGGTCCGCCCCCGCCCCCTCGGGAGCGCAGAGTTGCGGGGGGCCGGCACAGCCTCCGCCCTGCGCC
GCCCGCTCACACAATGGGACGCGTCGGGAGGGGGCGGCCGCGGCTCCCATTCCGGTCCCAGGGCGGGGA
CTCCGGGCGGCGGGAGAAGCAGTCGGGCTGGGGCCAGAAGGAAAACCCCCTCTCCCTCTGCCCACTCAAA
CTGCGAAAGGGCTCCAGCCGGCGGTGCCAGGGGCTGGGGAGCAGCTGGGGAGGGAGCGGAAGTGCCACC
CCCTGCAGTCAAGGGTGGTGACGTCACCCCTGCAGCCAGCCTGTAGGGGGGTGTCTGTACATCACATGAC
CCGGCCCCCCTCTCCCCGCCGAAGCCCGCGCGCGCGCTCTCTCCCCCAGCCCCGACTCCCACCTCTCCCC
CGCCCCCTCTCCCCAACTTTCGCCCTCCCCGCTCCGGCACCGTGTCAACAGCGCCAGCTCCGCCCCCTCCC
CGCGCCCTGTGGAACCGCCACGGCGGCGCGGCGGGCGCTCGCGCTCAGGTCCGAGGCTCCGAGAAGCGA
GCGTGCCCCGGTTCCACCCTGCCCCCCAGCTCAGTGCTGCTGGCTGCGTGGGCACCAGAGCCAGGGGGCA
CGGCGGCGTGCAGCGACAGCGCTTCTCTGCTCCATCCTCCCACAGCAGTTAGAGGACGAAGCTGAGGCGC
CGGGTCCGAGCTCGGAGGGAGCGAGGCGCATGCACGGCCTCCGGGCCCTGACGCGTAGCCTCCGGGGGT
CGGCCCACGGGCGAGAGAAGCAGCCGGGAGCCCCTCCTCGACCCCAGCAAGGCGGCCCGCGCCTCCGCT
CTCCCTACCGCCCGGGTGGCGCACGCCAGTCCCCGTCTTTGGC
103; ALL; chr13: 94152191-94153185; 13; SOX21; DOWNSTREAM
CGGAAGCCTCATCCCGCCAAGCCTTCGCCTCCTCGCTGAGACTCTGAGCTGCGCTGGGGTTGGCGGGCAC
CCGATTCCGCCCCGGCCCAGACCGGTCACTCAGTGTGTGCATATGAGAGCGGAGAGAAGCGACCTGGAGG
CCATGGGTGGGGGCGGGTGGTGAAGCTGCCGAAGCCTACACATACACTTAGCTTTGACACTTCTCGTAGG
TTCCAAAGACGAAGACACGGTGGCTTCAGGGAGACAAGTCGCAAGGGCGACTTTCCAAGCGGGAGATGGT
GAAGTCTTTGGACGTGTAGTGGGTAGGTGATGATCCCCGCAGCCGCCTGTAGGCCCGCAGACTTCAGAAA
ACAAGGGCCTTCTGTGAGCGCTGTGTCCTCCCCGGAATCCGCGGCTTAAACATTCTTTCCAGCTGCGGGG
CCAGGATCTCCACCCCGCGCATCCGTGGACACACTTAGGGTCGCCTTTGTTTTGCGCAGTGATTCAAGTTG
GGTAACCCTTGCTCAACACTTGGGAAATGGGGAGAATCTCCCCCCCCGCAACCTCCCGCACCCCAGGTTC
CCAAAATCTGAATCTGTATCCTAGAGTGGAGGCAGCGTCTAGAAAGCAAAGAAACGGTGTCCAAAGACCC
CGGAGAGTTGAGTGAGCGCAGATCCGTGACGCCTGCGGTAGCTAGGGCATCCAGGCTAGGGTGTGTGTGT
GCGGGTCGGGGGGCGCACAGAGACCGCGCTGGTTTAGGTGGACCCGCAGTCCCGCCCGCATCTGGAACG
AGCTGCTTCGCAGTTCCGGCTCCCGGCGCCCCAGAGAGTTCGGGGAGCGGTGAGCCTAGCCGCCGCGCG
CTCATGTTTATTCACGCGGCCTTGAGCAGCCGAGCTCCAATCCATATTAATCAACCGCTCGACCTACACAA
GTCTAAGTTTACGGGAGAAAACCTAGTCCCCGAAAGGAAGAACAGCAATCCGGACAAGCAGTTGGCGCCT
TTGTCCCG
107; ALL; chr13: 113930978-113931584; 13; chr13: 113931540-113931584; Unknown
CGACCCAGCCCCCGAGGAGAACCCAGAACCGACCCAGCCCCCGAGGAGAACCCAGAACCGACCCAGCCC
CCGAGGAGATCCCAGAACCGACCCAGCCCCCGAGGAGAACCCAGAACCGACCCAGCCCCGAGGAGATCC
CAGAACCGACCCAGCCCCCAATGAGATCCCACAACCGACCCAGCCCCCGAGGAGATCCCAGAACCGACCC
AGCCCCCGAGGAGACCCCAGAACCGACCCAGCCCCCGAGGAGACCCCAGAACCGACCAGCCCCCGAGGA
GATCCCAGAACCGACCCAGCCCCCGAGGAGATCCCACAACCGACCCAGCCCCCGAGGAGACCCCAGAACC
GACCCAGCCCCCGAGGAGATCCCAGAACCGACCCAGCCCCCGAGGAGATCCCCAACCGACCCAGCCCCCG
AGGAGATCCCACAACCGACCCAGCCCCCGAGGAGACCCCAGAACCGACCCAGCCCCCGAGGAGATCCCAC
AACCGACCCAGCCCCCGAGGAGACCCCAGAACCGACCCAGCCCCCGAGAGATCCCACAACCGACCCAGCC
CCCACGGAGAACCCAGAACCGACCCAGCACCTGGGCAACATTCTGC
111; ALL; chr14: 36205192-36206099; 14; PAX9; INSIDE
TCAGAGAATTTGGAAAGGCCTACTCTGAGGGGAGTAAAACTTCACCAGGCCCTGGGCTGGAAGCACAGGA
GGTCGCGGCTGGGCCCAGCGCCCTCGGGAGGCCAAGGGCAGGGAGCCGACCCAAGGTTAAGCCCTCCAG
CTCTCCGTCGCGGGTTTGGGTCCCGTCTCAAGAGTGGGGCGCGCGGGCTGGGCCTCCGGCCTGACACCCT
CTCTTCTCTCCATCAGTGAGCGACAGCTCCCCCTACCACAGCCCCAAGGTGGAGAGTGGAGCAGCCTGGG
CCGCAACAACTTCCCCGCCGCCGCCCCGCACGCGGTGAACGGGTTGGAGAAGGGAGCCCTGGAGCAGGA
AGCCAAGTACGGTCAGGTGAGGAGGCGAGGGTCAGGCCAGGTGGGCCGCGTGCGGCGGGGATTTAGGCG
ATGGAACACTTTGTGATGGGTCCCTTTCTGAGCTTCCCGCGAGAGAAGCCCAGGCTGGCGTCCCTTTGCT
GCTACGAGCCAGATCCTTCGTGGACTGGGGCGAAGCAGAGGCCTGAGCTTGGAAGGCGGAGCTGGGGCC
TCGACCCCCGCCAGGGGCCGGGAGCGCTCGTCAGGGCGCTGGGGGTCTGGGGCGGCAGCTCCCCGGGGC
GAGGCTCTGGGAAGCGCCTCCAGGCCTGTCGGCCTCCGGGAGCTTGGGAGGCGGCTCCCGAAGCCCTTTC
GGCGGCTCTCGTTGGGGGTAGAGTTAACCAAAGAAGGCGCTTCTGAAGGGCCGAGCGGAGCAGCCCTGG
GGCCTCAGAGCCGCGCCTTCACGCCCGCGAAACGCGCGCCCCGGTCTCGGCCCCACGGTGCGACTGCGG
CTGCGGGGTCCTCACGTTCGGACTTTCTCTCCGGTGGCTCTCGGACAAACACGCTTGGCCAATCCTGCG
130; ALL; chr15: 94688798-94689131; 15; NR2F2; DOWNSTREAM
CGCTACGAATGTAAGATGAATTTAGTGGCGCGGCTGCCTCCCTGAATCCGAACGGTAATGATGGATTTATC
AACGGGGATTCGCCTTCAGCCCAGCGAGGGAGGTTTACTCAGCAAATATGTCGGCGGCACCCACCCAAAT
GCAATCATTTGACCCCCTGCGGACGATAGCTGCCGTGCCCCTTCCCACCGCTGGTCCTGCTTGGCCAGGG
TCGCTGGGGGCCAGAGGCCGGCCCGGATGACCAGAGAGGTGGCCTCACGGATCCTTGGCCTCTCGCCCC
CTCCTCTGTTTCCTCCTCTCAGCTTGAGGCTCTCCTGGCAAGGGGGATCGAT
133; ALL; chr15: 94696311-94696840; 15; chr15: 094696796-094696840; Unknown
CGGGGGGGTGGGGCGTGGAGGGCGGCCTGAGTGCCGCGCCTGGCCCCTGCCCTGGGTGCGCACCAGGCC
GCGAAAGCCGGGGGCCGCCTTCTCGGCTGCTGAAGCCCGGGAGTCAGTCAAGCGCCCTTGGCACCGCGA
GGGAGGCGCACCTCGCCTGGTGCAGAGTTGCCGCGACCCGAGCGGGAGGAGGCACAGGACGCAGGGCTC
CTGGCCTGGCTGTGGGCTTGGCCTTGGCGCACTAAGCGCTCCCCATCTGCCCGAGCTGGCCTCCGCGGCC
CTCTCGGCCCAGTCTACGTTCGTTTAAGGACTTCAGCGCGAAGAAGAGCGAACGTGGCTAGAACCTGTTG
ACCTCTCCTCTGGCCTGGAAGTCCGCACAGCTCGTGGCAACACTGGACGGACGGTTGTCAGGGGACGACC
GCGGGCAGGTGGGGAGGAGGCCTTGGTCTGGCTCCTGGATTCCACCCTGGGACGGAAGGGGAAGCGGAA
ACCTTGACCTCAGCCACACAAGGACACCTATCTGGCTGTCT
134; ALL; chr15: 94705727-94706054; 15; chr15: 094705808-094705853; Unknown
CGCCTGCTGCCTGCCGTGGGGCCGCTCCGAGGTGCCAGGAACTCCGGTAAGGGTCCCGGCGGCGGCAGC
CCGGGAGTGGGCAAAGAGGGAACATGCGTGTATTTCAAAGAAACCAGCGCGGTCTCTGACTTCCCTGTCT
TCGCTCTCCACCCCCGCTCCCCCTCAACACACACATAATATAACAGACGCGAAGATAATCCTGCCATCTGG
CAAATCCCAAATTTGGTGACCAAGCTCGGAAAGCAACAGCGACGGCTCATCCCGGAGTAGGTGGCTGGTC
CTGCCGGACTCTCCGGAGCTGGGGCAAGGGCCGTGGGCTCTGCCCG
136; ALL; chr15: 94712480-94712812; 15; chr15: 094712480-094712531; Unknown
TAGGACCTGAAATTGCAGAGACATAGAAAATCAATACGTGGTCGGGAGTCAACTGCGCGCGACCAAGGGC
TCTGCCCTCCCTCTCTCCGTTGATTTGGACGCTGGGAAGCTGCCCGCCGTCCTTCCCACCCCCTTTGCCCA
GCCTTGGCAAGACCTCTCCGGAAACATACTCGCGTTAAGGAACTGGGAAAGCTTCCTGGCCCGGAGCTAG
GAGCCCGACGTTGGGGCTCCTTGCTGAGTGAGACGCTCAGTCCTGTGCTCCCGCCCCGCCCCAGGCGCCC
AGTCCCGCTGGGATCCATCTCCTCAGCCCCGGTTTCCCGCTCTGCGAGCG
145; ALL; chr16: 52873104-52882105; 16; IRX3; PROMOTER
CGCGAGGATGGGCGGGCTCCACGTCTGGGGGCGCTGTGAGCAGGGCCAGAGCGAAACCTCAGTCTGAGT
TTACGAACTGGGAAGGAGCCTGAACCCCAGAAACACCGTTAACAAAGAGGGCGAACGCAGGGAGCCGAG
GAGACGTCTCCTTGGCCTCTGGGGAAGGGGCTGGAGGAGCGAGCCAGCTGAGAAGCGGCTTTGCCGGGT
GTCCACTAGCGGTTCGCCAGCCCTCTGTGCGCCCGCAGAGTGACGCAGAGGCCGACCAGTCCCCTCCCCA
CTCGCCCCTGGGGCGCCGCCGCACCTTGATCACCCCCTTCGCGGAGGGAACTCCCAAGGCGCGGCGCTGG
CCGCTGGGTCCGCATGGCCCAGTCCTGTCGGGCTCCGCTCTGCTGCCGCCGACTTCGAAGGTGTGCAGTG
TTGAGCCGTGTCTTGTTCCGTGGCTTCGAGGGGTGTGCGCGCTTCCTATACCTCCCCGGAACGCGCGAGA
TAGTCACACGCGCCACTTTGAGGGTCAAACACCCCGCATCTGGCCACATGTACCTTTACTAACGTGGGGA
GGGGGCAAAAAAATGTGTCTCTCCTTCTTACCCCGAGGTGTCACTCGCCCAAACACTCCCTACAACTTCTT
CAAGTCAAACTTGGGCAAGGTTGGCTGGCTGACTGCGAGAGGAAAAGAGGGCGCGGAGGGGGCGCGGCG
CGCGGCCGGGTGTAGAGGCCACGGAGGCGAGGCGCCGAGCGTCCCCTTTGTCCTGTAGAGGGAGCTCCA
GCCCCAAATTTCCCTGCTGCCTCCCCCGGCCCGCCCACCCCGGCCCGCCTGGAGCCGGAATCCCGGCTGG
AAAGGTGCGGCGGTCTGACACCCCCGCAACCCCCGCGCCGGGGCCTTAGCAGGATGCCTCTTCTAGGGCA
CGTGGGAAAACCCACCAGGGTGCCAAGACGCACAGATCTCCCAGGACCCGGGCTCCCCAACTCTCAACTA
GAGCTGGGCAGTCACACATCATCTAGAGGATTATGTACCCCTAGGCGACCCTCTTCTCCATATCCGCCTCC
ACCGTCACCCCACACCCTGGCATCTATAAAGAGGAAGGGGGGCAACCGGGTTGGAAGGAGGATGGAATCT
GGGCTTGCACAGCCTCTTATAGGTAACAGTGAGAAAGCCTCAACTGTGTCGATCAAAGAATGGGGACGAA
GGGAGTGATGAGAACACGACCCCGCCACCGCGCAGGCTA
153; ALL; chr16: 86294154-86294408; 16; KLHDC4; DOWNSTREAM
CGTGTGACACTTTGGAACGCTTCTCTCGTTACAAACCAGCGTCTTTACTGAAGGTCCTTCCGCTGCAGAGC
TGCGCAATGGATGTGTGGACAGAGCTAGTCGGCACGTGGAGGCTCTCCTGGTTTTCAGCAGGAAACGTGC
TGTGAGCAGGAATCGCGAGTGAGTTCCATGGCGTCCCCGGGTCAGCGCGCGTGCAGGAATCGCGAGTGA
GTTCCATGGCGTCCCCGGGTCAGCGCGCGTGGGGTCCTGTCTCG
155; ALL; chr16: 87372445-87372729; 16; chr16: 087372616-087372660; Unknown
CGGCGGGGAATCGGGTGGCCACGCACGTCGGCCTAAGGGGCCCTGGCAGCGCCCGGCAGGACAGCCGTC
CACTGCACACCTCAGAGCCGGCACCCGGGACGGTCAGCGTCCCCATGGGCCCGGCACCGCAGCTGCCCA
GATCCTCACCCGCACACAGGAAGGGTCCCTGCAACCCAGCGTCCACCGTGGAGAAACATGAACGTGAGCA
AAAATACGGCCTGCGGTGGGTGTGCGACCCCACACAGAAGGGCGAGAGGCTCGTGGCCATCCCACACACT
GGGAG
165; ALL; chr17: 44074280-44075233; 17; hsa-mir-196a-1; PROMOTER
TTTCGCTAGATCATTTGTTAATTGTGGGAAGGAAGGACGCATCCGGGGAGAGGAGATCCAGGGCTGGAAA
AGTGGGTGAGCGGCGCTGGCGCAGGCGGCCAGGAGAGAGCAGATGAACCGTTCGTTAGAGCAGCGAGGT
AGTCGTGAGCGCTGAGATCCAGAGACTAGGACCCACTCCCTCTCTGAGCAGCAAATTGGGAAGAAGATGC
TCACTCGGTAAGGGCGAGGGAGCCCGGCATGGCGCCCCACCACGGGCTCGGTCTTCTGCGCGCCAAGATC
CCGCTTGGGGCGAGGCGTTGGGTCAGCGTTTAGAGCCACTCCCTGCGCTGGTGGCTGGACATAGCCTCCC
TATCCCACCTCATCTTCCCCCATCCCCGACAGAGGAGGTTGTGAATCTACGGCCCTTGACGTTGAGGCGTC
GGAGGGCGCACCTTTGTAATTGCGGCCTCCCTTCGCCCCTTAAGTGCCGCTTCTGGGCGCCTAGGCTGGA
TATGAAAGCCCCGTTCCTAATCCTCTGCTCTGGTCCCCTCCTCTGACTGCTGGGACTCTAAGCTAGGCCCT
CCCCAGGTTCCATCACTGCGGCGCCAACCCGCGGCTGGGCTGTCCGCAAGAGGGAGTTGAAGGCGCGCG
GAATCCCGAGGTGCAGCTGACCCTCCTCTCAACGCCGACTCGCCGCTCCCGCCCGGCCACCTCCCTGTCG
GGCAGACTTCCTGTTCTCCTGCTCACAGCAGGGAGGCAGTCGCCGAGCCGGTCAGCAGCGTGCACGGAGA
TCTTCACTCTGCGCCCAGCCCCGGGACACAGGTGCAGTCTCCAGCGGAGCACTGCGGAGTGCGCGCCGTC
GAGCACTAGGGAATCCTAGACGGAGGACTTGGTCCATTCCACGCAGTCCCAGGCAGGTCCGCAGCGGAGG
GACGCAGCGGTCTCCAACTCCTGGTCACGACTTGGCG
172; ALL; chr17: 58865328-58865618; 17; CYB561; INSIDE
AGAGGAGGCGGAGACCTGACCCCAGAAAGCAGCACTCAAACAGATGCAGCTGCACCCACGCGCCCGCCT
GCTGCCAGAGCCACTCTCCGGAGCCTGCAGTCCTGAAGACGCCTCAGCAGGGGCAGGCAGAAGACACCCC
GCGAACCCCCAGGGCCGGCCGGGCGCATCACTGGGAGCCGGGGCTATCTCCCTCCGTCAGCGTCTTGAAG
TCCATGGAGAGGGCCTGCTCTTCCGCCTGGGAAGGCCGCTTCCAGTCGGCCCGGTCAAGATGTAGAGCAC
CGCCCCACCG
176; ALL; chr17: 73932992-73933361; 17; DNAH17; INSIDE
CTTCTGCAGACAGACAAGAGCCCTCCTTACCTTCCATGAAGAGTCCGTACACGTAGGAGCCCTCTCGCGG
AGGAGCGGTCATGTCCTCTCGGTTTTTCTTGGTCACCTCGACAGACAGACACATCTTTCCAGGGGCCACTC
GTTCTTCCTGGCCATGGACTGCATGATGGCCGTGAGGAACGACTGGGGGTTGAAGAAGCCGGCCAGCCAC
ACGGTGGTGGGCAGGGCAAAGTCTGTCGTCCAGGCCTCGAGTTCCTGCAAGGCACACGAGCCGCTAGGA
GGAGAGGACATAGAATGACATGGGAACGACCGGGCCTTGGCCGTTCTGAGCAGGGGTCACGCCAGAACC
TTCCACGGGCCACTCAGCG
181; ALL; chr17: 75531280-75531546; 17; TBC1D16; INSIDE
CGCCTCACGGGGCCTGCCAGCAACGCGCTGTGTGCAGCAGGAAGCCCACGCCAGGTCCTGACGGCTGCAT
CCTGTGTGCTCTCCGGCCTGGCCGCCTCAAGACACGCCACCTTTGATGCACACGCGCTCCGGAGGCACAG
GAAGGACGGGGGCACTGGGAAGTCCATGTTTAGTCTCCTGACGTCGACCACACAAACCAGACGGAACGGT
GTCCCCGGCCCAGGCTGAGCGGAGCACACCATGAGGGCAGAGGCTACAGGTGATC
183; ALL; chr18: 5186244-5187389; 18; chr18: 005186349-005186393; Unknown
CGTCGGACGTTCACAACGACCACGCTTTTCCCCGCTTCCTCGATTAGCCTGGCCTCCCTTGCTCCAGTGGG
GCGGACTCAAATGCGCACGCACGCACACGCCGCCAAGCCGGTCAACCGCAGACAAACTGACTCTTCGCCA
ACTAGTAGCCACGGAGAGCAGCAAAGGGACCAAGGTCCTTCACCGCCTGCTCCAAAAAGACACGGCAACC
TCCAGCGGCGCCGCAGTAGCTGCCTCTGTGCTGCAGCCTCCGGTCGGAGTTTAGGTCTAATTCCTTAAGA
AGTATCGCTCCTCTGCCCTTCGTCCTACTCCCCTTGGCTTCGCCCACTTCGCCTCCTTCTCCTCGGGAGGC
CAGGAGGACCCGGGTCACTTTGCCAATTCTGCGGAGGGGGAAGTAGCGTGAGGGAGATTCCCACGCAAGT
AGCCCGAAGCCCACTACTCTTTGCCCCACCTCTCCACTCTCTTGCCCGTGTAGGTGCCGGTGCTGCTGGCG
AAAGTCCCAGTTCTTAAGGCTCCTGAGCTCGGAAGGGGTGTGAGGAGCCAGATGGGAAGAGAAGCAGCG
GGACGAGGGCGAGGAAGGGCTGGAGATTGTTAGAGGACAGATGGGGCGGGACTGGGGAGAGGGGCGAA
GGCGACGCGCCGAGGCACTCCTCCGCCCCATGAGCACAGACGTAACTCCGAAACGCGCAGATGGGCCGTA
AGGTAAAGAGGCCTTTTTTCCCTCTCCTCTCCGTCCTCTACCCTGCTCCCCTCCTAGACACTTGGTGAAAA
AGCAAGGTGCGGTGTACCTGGAGCGAACACCATGATTCTTCCAGCCGCTACGCCCCCAGATTAAGAGAGA
AAGACAGGCAGACGGAGGATGGGAAGAAGGCCGGACTTGGCGGGGTCCGGTGCAGGAGGGCGCGCTGG
GCGGGCGGCGGGCGGGGCGGTCAGCACCCCGGACGCTCCCGCCGCTAGATCCTGGGGCCGCAGCTCCAG
CCGCCGCCGCGCGCTCTGCCTCCACAATGCGGCCACAGCGGCGGCGGGAGGAGGAGGGTGAATCCCCGC
TCAGTCCATCCCTCATTCCTGTGCCAGCTCGGGACGTACACTGCTGCTTAGGGAGCAAAGCACTTCCACCG
CTTTCACGCGACGAAGGTCG
193; ALL; chr19: 4059891-4060207; 19; MAP2K2; INSIDE
GACCACAAAGCGCTTCCTCATCCTTTCCTCGCCCTTTGATGCCGCCGGCAACGTGACTCTGCGAGCAGCG
GGGCAGACGCCAGGTCTCCCTCGCAGGCGGGAAAGGGGCTCCAAGGCGGGTGCTGCCTGCTCGGGTCAC
ATGGCTACGTGGGGGCCTTGCTCAAATTCACTTCCTGCCTTCATTACAAAACTGTCAAAGGGGATCGCACG
TTTGCAGGGTGTCACCCAAGCATTCTGGTTTTGCAAACGACGCTGTGCGGCAGCGGTCTGATACCTGATG
AGCTCGGTGTGGCGGGGTCGGCAGCATTTCCTCCG
209; ALL; chr19: 63784504-63785085; 19; MGC2752; INSIDE
CGGTGTCTGGAGGAAGCGGCGCGGACAGTCTCCCGCTCCACCGTGTCGGGCCTGAAGAGGCCGCTGAAC
GCTCGCGATTACTGAGGCATCTGGTAGGATCGCAAGGCCATCAACCTACAGGTGAAGCCGAGGCGCTGTG
GCGCTTTGAAGCCGGAGAGAAGCTCAGTAGAATCGGGAAGGCGCTGGGGCTGTCCAACTCCACCTTGGCC
ACCATTCGTGACAACAAGGAAAAGATCTGGGCGAGTTCCCAGGAGGCCACACTGAGGCGGCCACCAAGTT
GACGCGTGGCCGCAGCCTGGTGATGGAGAACATGGAGCAGCTGCTGAGCATGCGGATGGAGGACCAGAG
CCAGCGCAACATGCCCCTCAGTGTGGTGCTCATTCGGGAGAAAGCCCACAGCCGTTCGAGAACCGCAAGC
AGGAGCAGGGCGAGGGCGCCTAGCCCGAGAGCTTCGGGGCCGGTCGAGGGTGATTCGCTGGCTTTAAGG
CGCGCCACAGCTTGAGCAGCATCGGGGCCAGCGGCCCAAGAACGCAGCTGCAAGAATCCAGCGTTAATGC
GCAGGGTGATCCCGGAGGGCG
210; ALL; chr2: 19424445-19425131; 2; OSR1; PROMOTER
CGGCCGTTCGGTGCTGCGGTATCCCATCCCCCGCCTGTTTAAGAGAAATTGATCACGTTAAGCGGGCCCT
GCGTCGCTGCGCAGTGCCCGGACTACCGCTTGGATGGATTGACAAGGGAAGGACGCAGACACCTAAGAGC
AACAAGGGTACTTTTTAAGCGAGGTTACATGTGTTTAGGACTCGCGAGGACGTCACGTTTCGAATTTGGTA
AAAGTCCTCGGTAGCTAGGACCCAACAGTTCTGCCCTCCTGGAAACCCAATGAGGTGACAAAACTCCCATC
TCATTACTGGGAGTCCAGCGCACTCCGCCACCGCGGCTGCAGCTTCTGCTAGCTCGGAGCCTGCGGACTC
CAGCCGGCGCGAACTCCGCCGCGACTCTTTCTGGCTCTCTCGCTCACGCCTTCGGGGCGGAACCGCGGGC
GCCGGAGTGGTCCCAGACTCGGCTGGGACCGGGCAGCCTAGAAGAAGGGTCCCCTCAGTAGAGACCAGG
CCTCCAGCTCTCCGTCCGGCGCTCCGCTCCACAACCCGCCAGTCATGTGAGGTCCGTCAAGGGAGCGATC
CCTCCGTCTGCCCGGGCTTCCGGGCTGTGGACCGCACTGAACCCAGTCCCGCAGCAAGCCCTGCTGCCGC
CTTTTCCTGGGCACGCCTGCGGTGGTGACGGCCCGCTGCTATGTCTCCACG
212; ALL; chr2: 43251514-43251780; 2; chr2: 043251514-043251559; Unknown
AAACACAGTGCCGCAGTGAAAGTGGGACAAACGCGCCTGTGTGCATCCTGGCCGAGGTGCCGGAGGAAG
CGTGGTCGGGGCAGAAGTGTTAATGGGCCTCCTTCCTGCCGTGCCCTGCCCGTGCCAGTCCTCGGTGCTC
ATCCCGGCTCCCTGAAATGCTCGCTTCCACTCAGGGCCAGCGCACTCCCTCCACGTCCCTGGCCGCAGAT
CTGTCCTGCTTTGACAAATAACCCGCTCAGCCTTCGGGTTTATGGTTTTTCCGTCG
214; ALL; chr2: 45249374-45251726; 2; chr2: 045251412-045251456; Unknown
CGCTCCCTTTCCCGCACACGCATTGCTGCCTCCTCTCGGGCTTGGTTAATGAGTCTGTGCGCCAAGCCAGG
TCGCTCCGGGCAGTTCGCGCTTCCGCGCCTCGGCACTCGGATGACCGTGTCCTATTGTCTCTCTCGTGAAT
GTCGCTGAAAAAAAATAAAAGTTTGTTCTAAGCCCGTGGCATTTCCGCGCGCAGATGGAAAGGCAAGTGG
GAGAGGAGGGTGCAGGTGCGGGGCGGGCGCGGCGGCCCCTTCAGGCGCCGGGGCTGGGCTGCCCCCGG
CCGGGAGCAGCTCCGCTCCGCGCACGTGGCTGTGGGCGCTGCGGACGGGGGACGGCAGGCGGGGGACG
GCAGGCGGGGAGTGGAGGGTGCAGTGCCCGCAGGTGCCGACGGCTTCCTCCAGAGCCCTTCGCGCCGCG
CCTTGCCTGGCTGGTGGCGCGGGGAAACCATGGCAGCATTGCGGCTCCGGCGGGCGGGCTCTGCGCGGG
GCCCCACCGAGCTTTCCGGGAGCCTCTCCCGCAGCCGATGGGCATCTAGGGCGCAGAACGAAGAGTGGG
CGCCGAAACGGGTGTAGGCGCTGGAGGCCGACGGGGAGGCCCGGGGCGGTCAGGCTTCTCGGTAGAGAG
GGCCGTGCACCTCGCGGCCTGCGGGCTAAGGCGGGGAGCCGCTCCTGGGCGGCCGGGCGCGCGGACTGG
AGGGAGGGAAGCGCCACGGACTGGGGAACCGGGGTGACGGGGAGACGGGGGGGCTGGTGGGGTGAGGT
CGGCGGGCAGCAGCCAAGTGTTCTGCAGCTCCGAACCCCGCCACCCCTGGGCGAACGGAATGGCACCCG
CGGAGACGGGCGGGGACGGGCGAAAGCGGGTTTGCTCCGACCCGAAGCTGAGCCCGGGTTGGAGGGCGA
GACCGTAGGCGAGAATGGCCGCGCGGGCTGGGAGACCCGGGCCGTATGGAGTGAGTGGAGCCGCCCGAG
GTAGGGTAGTTGGGGATGGTAGTTGTGAAGACAGTCGGAGTCTAGCTCCGGGCAGACGAAACACCGGGG
CGCGCCAGGGTCCGTTTCCTCCTTCTCTCTGCTTTCCCACCACCCTGTAGATACGGAGCCAGCAGTCGGGC
TAGAGCGGAGGCTGAGGGTCGCGGTTCCAAGGGCGGTCTCTCGCCCCGGGTCAGGCCCCACCCCGCGGT
GGCGGTCGCGTGGCGCTGTCCTGGAGTTGAGCTGTCCCGCGCCGCGGCC
217; ALL; chr2: 63134470-63134933; 2; OTX1; INSIDE
CTCGAATCTTGGAGACACTGGCTTCTAGTCGCACATCTGCACTTTCTCCCACCTGTGGCCTCTCAGGCTCG
GCCGCCCGAGGGAGTTTCTTTTATTCCCAGTTCGGCTTTCTTTTGCGAAGGCCGAGTCTGGGCCTGCCAGG
GGCCTGCCCGAGTCCTCTATCGCGGGTCCACGTGGCCACCAATGACCCGCGGCGCCCCCGCGTGTCCCCG
CAGCCACTCCGCGGAAGCAGCGGCGGGAGCGCACCACCTTCACGCGTTCACGCTGGACGTGCTCGAGGC
GCTCTTCGCCAAGACTCGCTACCCTGACATCTTCATGCGGGAGGAGGTGGCGCTCAAGATCAACCTGCCG
GAGTCTAGAGTCCAGGTGCGCACTCCCCGGGCTCCAGGGTCTGGGTAGGGAGCTGAGGCTGCTCGGGGA
AGGTCTAGGAAGGCTCTTGAGTAGTTCTTGAGGAGACCATC
220; ALL; chr2: 66525936-66527222; 2; MEIS1; INSIDE
CGGTTTGGAGAGGGGAGCGCAAAGCGCTGGACGCATGCGGTACAGTGCCACGGCCGCCGGTGGGCTCCA
CTGCCCTGGGGAGCTGAGGCGCGACGAATGAAGCACCAGGGCGCCTGGTGGGCGCCAGTCTCCGGTCTG
GAGCCTGCTGGCCTGTCCCTCCGGGGCGCTGAACCCCTAGTGCGGCGTCCTGGGGGCCGGGCAGGAAGG
ATGGCCTCTCCACCTGTCTGCGAATGCAGCCCAGCCAGTTTGAGCCTCCGCAGAGGTGCGCTCCGGGACT
GGGCGCTTCTCGTGCTGTGAGAACGCTGGGCCTTGTTAGCTCATTAACCCCTCTGTCTCTAGGGCCCGTTG
GCGGCACGGTTTATTTTATTTTACCTGTTTTCCTCGGAGGGCGCGAAGACTCCACCCGCGCGGGGACCTG
GGATCGACGACTTTGATACTAGGCGGTATCCCGGAGGGCTAAGTCGGCGGAAATCCACTTGACCTTGTAG
CGTTAGTCCTTTCTTTTCCTTTCCTTTCCTTTTTCTTTCTTCTCTCTTCCTATTTATTTATTTATTTTAAAAAT
AGGATTAAGACACCAGTAGAAGCTGTAATCCCGTTCCTTCCCCCACTCCCAGTCTTCCGGGCCGCCTGGAG
GTCCCTGCCGGAGAGAGCCACTTTGGCGGGCGCAAGCCCCTGGGCGCCCTCTCCTGACCGCCGCGCTCTC
GGCTCGGCTTGGCTGTTCCGGGCTCCCAGAGGCTAGGGGAAGCGAGGGGCGCCAGGGGCTTCCCGGCCT
CAGCGTGGGGCGAGGTCCCGGCTGCGACCCCGGAGAGAGGGAGAGGGGGGCCATGATGCTAGGCGTCGA
GGCGAGGGTTGAGCCTGTTTGGCTTCAGAGAACGATGCGGGTTCGACCGGAAGCGGGGCGCGTGTTCTA
GGGGCCCTTGGGTGGATTAGGGGGCGCCAAGAGGGTTAGGCGAGGAGAGGCCTGGCCACCCAGTTGCTA
GACTTTAGGCCGCACTCCAGGAAGGAGCAGTCGGCTTCCTTCCTAGGCCGCTTCTATTGCGCGCCACTCCT
TGAATCTAAGCATTTTCCACTCCAAGAACCGTTGGGAGAGAGGGGAGAGCGGAGCAGAGTCTCTAGGCCC
CCAGGGCCGCCTCCCGGGGTGGCCACGCCTGCCGGTAGCGAGCCGAGATTAGCTAGGTCTGTGCTCGGG
CCTCAGCGGTGGCCCTGGCTCTTCCCTAAGCAGCGGG
222; ALL; chr2: 70984709-70985764; 2; VAX2; INSIDE
CGGGCGCATAACAGGCACCCCGCACATCGCACCGCGGACGCAGCGATCCTCCCATTTGTACCCTAAGGCC
TGAGAAGGCCGCTCCACACCTCCGCGTGCACAGTCCCTAGACCAGTGAGGGCGGGGAGGGGAAATCCTTT
TGTTTTATATTGGAAACCTTACGCCAAAGGCAGGCAGGAAGCAACCAAAGGAACAACAGGCCGCCTGAGC
CGTGGCTCAAACAGCACAGGGCAGTGGCCGAGCACCAGGCTTTTCGGTGGAGCGGGATACCAGCAGGCA
GAAGAGGTGGACAACTCTGACCGCAGACTCCCTACAACCCCGCGATCGATGCTCCACCTGCACGCTCAAA
CGCACCTGTTTCCCAAATTAATCCAGACGCGAATTTAACGACCGATTTTGTAGATCCGGGAAATTCTGTCC
ACCAGCGTCACCCAACACAGCAACTTTTACAGACAATGCGTGGCGTCCGTTCCTGCTCACCCAAAGCGGC
CTCTCTGGGCTGACAGCCACCCCTGCGGGTCCTCAAACCCCACTCAAACCCTCCGAACCCCTGTGTCTGG
GAGCAGTAGGGTGGGATGACTGCAGGATCCCTTGAAGAAGTGACTCGCTGCAACCCCACCACCAGCAGCA
AAAACGCTTTCACCCGGGAGCTGCATGGATGCGCGGATGGCGGGGGCTGAGGGGACGCGTGAAGCCCAG
GCCTCTTGCTTGGGCTGGGCGATTCCCGCCGTGGGACGGGTGGGATTGACCTTAGTGGAGTCCAGTCCTT
CGGAGAATCCGCGGGCAGTCGGGACCCACGCTCCGGAACACCCAAGTCCGAACTCGTACACACAGCACAA
TGGCGTGCAGCCGCCGGGGCCCTAACTCCCAGAGACGCGTCTGAAGAAGCCATACAAGGGGGCGCAGCT
TCGGGGCTCTGGCTGGGAGGTTACTGCAGGGACAGCGCCTCGCCTCCAGCAGCCGGGTCCAGGCTCAGG
GCCGGCCGGCCTCTGCTCGCTTTCTGCTTGGATTACCAACAGCCACTGGGCTTGGGGAGATCGGCCGGGC
CG
230; ALL; chr2: 105864220-105865009; 2; NCK2; INSIDE
CGGCAAGACGCGCAGGAAGACCAGCGCGCGGGATGCGTCCCCCACGCCCAGCACGGACGCCGAGTACCC
CGCCAATGGCAGCGGCGCCGACCGCATCTACGACCTCAACATCCCGGCCTTCGTCAAGTCGCCTATGTGG
CCGAGCGGGAGGATGAGTTGTCCCTGGTGAAGGGGTCGCGCGTCACCGTCATGGAGAAGTGCAGCGACG
GTTGGTGGCGGGGCAGCTACAACGGGCAGATCGGCTGGTTCCCCTCCAACTACGTTTGGAGGAGGTGGAC
GAGGCGGCTGCGGAGTCCCCAAGCTTCCTGAGCCTGCGCAAGGGCGCCTCGCTGAGCAATGGCCAGGGC
TCCCGCGTGCTGCATGTGGTCCAGACGCTGTACCCCTTCAGCTCAGTCACCGGGAGGAGCTCAACTTCGA
GAAGGGGGAGACCATGGAGGTGATTGAGAAGCCGGAGAACGACCCCGAGTGGTGGAAATGCAAAAATGC
CCGGGGCCAGGTGGGCCTCGTCCCCAAAAACTACGTGGTGGTCCTCAGTACGGGCCTGCCCTGCACCCTG
CGCACGCCCCACAGATAAGCTACACCGGGCCCTCGTCCAGCGGGCGCTTCGCGGGCAGAGAGTGGTACTA
CGGGAACGTGACGCGGCACCAGGCCGAGTGCGCCCTCAACGAGCGGGCGTGGAGGGCGACTTCCTCATT
AGGGACAGCGAGTCCTCGGTAAGTGCGCTGCGCCCACAGCTCCGGCTGCAGGCAGTAAATGCGCCTTGCG
CGGTGGGTCTGTGTGCCGCG
232; ALL; chr2: 111591678-111597436; 2; FLJ44006-BCL2L11; DIVERGENT_PROMOTER
CGACTCGGTGAAGGATGATGCCCGGAGGGTGATCTCGACCTTTAACATTCCACACACCTACCTCCACGCA
CCAATCGCCGGAATCTCCAACCCGCGGGCCGCGTGGGCTTTCTACCCTGCACCGCTGAGCCGCGGCCACG
GGAAGAGGCGCGCTCCCGGCGGCCCAAGCTGGGAGCCAAGCTCTAACGGGTGTGGCGGGAAGTGTGGTG
GCCCGCCAGCAGCTGCCACGACGCTCGCTCCACCGACGCCCAGAGCTGTGGCCGGGCCGGGGGCTGGCA
CCCGCTGGGCCGCCACTCTCGGGGATTTTGGTGGCAAAGCGGAGGTCCCGCCGAGGCTGGCGAGGTGCG
CGGCTGGCTGCTAGGAAAGAGATCCAGACGGTCGCCTGGTGCGCTGGATCCCGTGCCCTTTCCCTGAAAC
CCAGCCTGGCCTGACTGCAACCTCTCCCAACTTCAGTGCCGGATCCCCTAGACAATCAGGGTGGGCTCCC
CGCTGCGAGCGCGCCCCACAGCCGGGTGCCGCCAAAGGTCTCCTGCTGTAGCGGTGACTCACATTCCCAG
TGATTTAGAAAAACTGTGGTGCCGAGTGAAAGAAAAAAAAAAAAGCAAACACCCTTAGACAAAAGAAAAA
AGCTCCACTCTTTCCGCGAGCGGGAAAAAAGGTTTGGTTCAGCAGTGATGCTATTTCAGTGAATCAGACGC
TCTGGGGCTCTGCAAGGAAACGCACGGACTGGGAGAAGGAAGTGGGAGCCTAGAGTTTTGCTCTCGGCAA
AACAAGAACTCGGCTTGTCCTCCCAGGCCGGCGGTTTCCTACGGCAAGACAAGGCGCGGAAAACATTTTT
ACCATCTGACGCTGTAGTCTGTCCTTTAGAAGAGAATAGGTGAAAAGTTTAATAAAGAAATTAAGCGATGT
GGAAGTCGTTCCCGCTGCTTGCAGAGGGTGGGGAGCGGGCCTGGGCAATTTCGGAACTAGGAGAGACCA
CGTCGGCAAAGCCTGTGGTCCCGAACAAGGGCCATGGATTTCCCATTTCTCAGATCCCGGCTGCCCGACT
TCATTCTTGTTTCTTTCAGCACAAGCCATCCCCCTTCTCCCTCCCTCCACGTCTCTTGGCAGAGACAGAAA
GGGACACCGCTCTGCCCGCGTCCAGCGCGAAGGAGGTGACCTAAAACCCATGGGCCCTTCTCACACTGCG
TTCTCTGCGCTCCGGCCCAGTTCCGGAGGACCTCCCG
238; ALL; chr2: 156892636-156892878; 2; NR4A2; INSIDE
CGGGTTGGAGTCGACATGGGCCCTGACGAGGGCACTGATCAGACTCACCGGGGGCGAAGGGGGAGAGGG
CTCCTGTGGGCTCTTCGGTTTCGAGGGCAAACGACCTCTCCGGCCTTTTAAACTGTCTTGCGAACCACTGC
AAAGGAAGAGCCCTGTTAGCGCCGCTTTTCCGAGCCCAGGCCCAGCTGCTGCCTCGGTCCCTCCCCGGGG
AAGGCCGCAGCCGCGGGGCACCAGGCTGAGCG
240; ALL; chr2: 156893736-156894685; 2; NR4A2; INSIDE
TCCTAACCAATTTCATTCTGAACAGGGAAGACAGCTCCTAGCACATGCAAATGACCCTCTTCCAACTCCGG
CTCCAGCAACTTCGGGCGGGGGCCAGCCGGGTCGGCTGAATGCGAGGGGGATGCGACCTGGCCTCCCAG
TCTTTCTGCTTCCCTTTCTCAGACACCCGGAAGTCCCCGCCGCAGCCCATGGTCTCCTGCAGGGCAGCTTC
GGCGGACCCCGGAGAGCTGGGCAGTCCCGGGAGAGCTGGGGCTGGGCTACTGCACCAAGGCAGAGGGCA
CACTCCGAGGTCCCGGGCACTAGGGGCTCCCTACCTGCCTACTCCGCTCCCGCCATTGCTCACCTTAAAGA
AGCCTTTGCAGCCCTCACAGGTGCGCACGCCGTAGTGTTGGCAGGCCGGTTGTCCCCACACACAGCGCAC
AGCCCCTCGTTGGAGGGGGAGCCCCGCGACGGCGGTGAGGGCACCTGCGTGTCGAGCAGCTGAGACGCG
TGGCCGATCTGCAGGCCCGGGAAGCCCATGGACGCGGGCTTGCGATGGGGTTGGGCACAGCGAAGGTCT
GCCCGTCCACCACGTGGTGGCTGCCGGCGGGCTCCGGGTTCATGGGGACGTGCAGGGGCCCGTCGAAGC
GCATCTGGCAACTAGACACCGGGGTGCCAGGGGGCGATTGCTTAAGGAGAAGAGGGAGAGGCGGGAGAC
TGGCGTTTTCCTCTGCTCGATCATGTGCGTAGTGGCCACGTAGTTCTGGTGGAAGTTGTGGAGAGATCCC
GGGTCGTCCCACATGGGGCTGTGCTGCACCTGGAAGCCCGGGTGGTGGGCGTCGGGGGCGAGGAGGGCT
TGTAGTAAACCGACCCGGAGTGCGGCATCATCTCCTCAGACTGGGGGGGCAGGTGGCTGTGTTGCTGGTA
GTTGTGCATCTGAATGTCTTCTACCTTAATGGAGGAC
245; ALL; chr2: 171384729-171385226; 2; GAD1; INSIDE
ATACAATTACCCACACAACAAAGAGGGCCTCGGGAGAGTCGCCAGCCCTGGTAGCATATGAACCAGGCAC
CGGCGTTGGAGCTGGCCAGGGCAGGGCGGGAGGAACGCGAGGCCTGCGCGCCTTTGTTGGTGCTTTCGC
CTTGATGGATTTCTTTTCTGACGCTTTCCACATTTCCCGCTCCCTTTTGCCGCCTGGGGGTGGGGGTGGGG
GGTTAGCGGGCAGTTGTGTTAATTTGCCCTCCACTCCCGGCGCCCTTACGGAATCCCGGTGGCCGCCAGT
CGCCGGCGCAAATGCCAAGTCACCGGTAGGAGACACAACAGAGGCGATGACCTGAATCCGCACGTGGCCT
GGTTCGCCTGGAAGCTGCCAAAGCGAAGGCAAGAGAGCCCGGGACCCTGTGTAAAACAGCAAGCAGCAC
GTGTCCCAGGCACACTGTTGCGGGCCCTTAGCCTAGCTACGCATCCGCACCCCAGGCTTCAAAGGCGCGC
TGGGCG
254; ALL; chr2: 176737610-176738187; 2; HOXD3; INSIDE
GAAAGAGATCCGTGGGCTTCTGACCCTGGTTTAGGCAAAACAGGGGGAGGCGCCGAGACCAGCTCGAGC
ACTAGCGGATTTTGAGAGAAACTGACCGCAACCTCCATCGCCTTCCCCCTCTCTTTCACTTGGATGGGCTG
ACTCTACCCGTCGGTGATTTACGACGATTGCAGCGCTAGTCACAGCCTGGCGCCTGGTGTCCCCTCCCTTC
CCAAGCCCCCTCAGCTTTTCCACTGCCACCGGCGTACAAGCAAGTGCCGAGCGGCCTCCGCAAGTCGGAC
TAGCCTCCCGGCGTCCGAGGCCACCACGGGCAGCAGATTTTTGGTCCCCAGCGAGGCTGCGCGCGTTCGT
CCCGCCTCCGACCGCCGAGCAGAGCTGCTAGCAGAAGCAGGCGCCGGTACTTTATATAATCCTGCTGCTC
GCAGGGTGCAAGAGCGGGAAAAGTGCGGAGTAGGGAATTCTTTTGCTGCGCTGCCTCCTACGCGGAGCCT
GCTTTCCACTGCTGAAAAGTGCCGGGCCTTGGGAAGTGTTTTTCTTTCATTCCTTACCGAAGCGTTTACTG
CCGCCGTGGTCG
259; ALL; chr20: 35582018-35583550; 20; NNAT; PROMOTER
CGGCTGGCTACCGGTGCGCGGGGACCACACTCACAAACCGCATTCCGGTCTTCCCGCCCGAAAATCCGCG
CTGTGCGAGGGACCCACAAGACTGGCGGTCTAAAAGGGACCCGCCTCACTTGGAAACGGGCTGCGGTAGC
CACAACCCTCCGGTAGCGGTAGCGTAACCCCGTTCGGTGATCCAGCCGCACAGCGCAACGGGTACAAAGA
ACCCCACTGGCTAAGGCCGACCTACCAGGGCTTGGGGGAGGGGAGCGGAAGACGAGGTCGAAACGACCT
GTCCAGCAGAAAACTATCCCCAAGCATATTCCAACCACTTCTCCGTAGAGCTCATTCCTTCCGTGCATACG
AAGGGCGCCAATCCTTCCTGTATCCCTCCTACAGATACCGGGTGACTACGCTTTTGCGCCCAAAGCGCAGT
GCTCTGGCTCAGCTCCCTACAGTAGCGACCTCCACCGCAGATTCTCATCTCCTCGCTACCGTAAGAGAGAT
GTAAAGAATCAGACGGGTTACGCGCTCAGGCACCCTCATGAAGAGAGGACCTGGGCTTAAAACTCATTCA
GTATCAGGAAAAGAGCGCCGAGCACGGGCCTATTATGCCAAAGCTTCTGAAAGGGGCACCACGTTTTTTG
CTCTATGGGGCAGATGACCCCTCCCTAATTTCGGTTTTCATCCATCCCCAAGGTAGGCTTTGGAGTGGCAC
CGGAGACTGAGCTCAAATTTGCAGGCCAGGGACTGGGGAGAAGGGCGCCACACTAAGAGACCTGCACCC
CCATTCTCGCCCTGTACTCTACCCAGAGTCGTGGTCCCCTCCATTTTAAAGCAAAATCCAAAAGCAAGCAC
GGCGGAATCTTCTGGAAGGGGGCTAAGATGGAACTCAGGAGGCGGGGGTCGGTATGGAAAGAGCAGATG
GATTATTTTTTTCCTCTCCTGGCGAATGAGGGCGCCCCCAGCCACCCCTCCTCATAAACACCCCCCAAGGC
GCGCATGCGCACTTAGGTGGCGGGCGGGTACTTAAGGCGCGGCCACCGCGGCTGCGGCAGTGCGCCCAA
CAGCGGACTCCGAGACCAGCGGATCTCGCAAACCCTCTTTCTCGACCACCCACCTACCATTCTTGGAACCA
TGGCGGCAGTGGCGGCGGCCTCGGCTGAACTGCTCATCATCGGCTGGTACATCTTCCGCGTGCTGCTGCA
GGTAAGTCTGACGGGGTTTCGGTGGGAGAGGGT
267; ALL; chr20: 60061693-60062033; 20; TAF4; INSIDE
CGTCTAATCGATGGTGGGGCGAAGGGAGAGCCACGGCGGCCCTGAGTGCAAGCACCATCCTGAAACCAG
GAGCCCATGAGGCCGCGGGAGCCGGAGGACCAGGACCGCCCTCGCACTGCCCTGTGACAGCTCCCGGCC
CAGCTCTCTGCCGCTCTGGATCCGTCACTAAGCAGCTCCATTAAGTGCCCGGTCAGGCAGGAGCGGCAGG
GAAACACTGGGGCACCCACATCTGAACAGAGAAGATGCCCACCTTGAGAAGGTACCTGGAGAAGGGAGCC
ACGAGCGACGTTTATGCTGAGAAGCGGCATCCGTGCACCTCACCTCCGCCCGTCCACGCCG
281; ALL; chr4: 9756136-9756429; 4; chr4: 009756149-009756196; Unknown
CGCTCGGGTGGCCGAGTTACACCTGGCTATAAGTCATCCCGTGCACCTGACTAAATGCATCCCGTGCACCT
GACTAAATGCGTCCCGTGCACCTGACTAAATGCGTCCCGTGCACCTGACTAAATGCTCCCGTGCACCTGAC
TAAATGCGTCCCGTGCACCTGACTAAATGCGTCCCGTGCACCTGACTAAATGCGTCCCGTGCACCTGACTA
AATGCGTCCCGTGCACCTGACTAAATGCGTCCCGTGCACCTGACTAAATGGTCCCGTGCACCTGACTAAAT
GCGTCCCG
284; ALL; chr4: 111780013-111780343; 4; PITX2; PROMOTER
CGCGGAGAGACACAGGGAGAGGGAAGGGAGTTGCGCTGAAAAGACGCAAAGATACGCGCGTGCAACTCC
CTCCCCTTTCAGGTTTCAGAGGTTTGCAAACCAGGGCTGAGAGGAAGGGGCTCGGGAACTCACGTTCCTC
TCGCCCCCCTTCTGTCTGGAGTCTCGCCCGCCAGAGGCTGGTTAACCCCAGTCCCGGCCGCCGCAGACAC
TGCGCTGAGCTTTTGGGTCCTCGCCTTGCCCAGCGCCAGTGCAGCTGAAGTGAGAGCTGGTGGGAAATGC
AAATGGCTCCTGGAGAAATAGAAGATACAGAATGATTCTCATTCCCTCCT
302; ALL; chr5: 115810975-115811393; 5; SEMA6A; INSIDE
CGCGGCTGCCGCGGCTGGGCTTCCGCTTCTGCTGCAGCGTTGGGGTTGACTCTGGGGTGGGGAGGGCCG
TCAGGTCCAGGTGGTGCTGGTCTGCTTTAATGAGCATCTTGGCCGTGTTGCCGGGAGTGCGAGCTTGCCG
TTGTGCATGAGTGGCGTGAGGATGGCCTCCGGCTTTGGGTCTTTGGATTGAGTGTCCCCAAAGAGGCCGC
TGAGCTTGGTGACGCTGCTCATGGAGCCCCGGCGCGAGTGGGTGAGCTCCTTCTCTTGCGCTGCACCACA
GCCACGTCTTTGCGCCGATGATCACAGACGCAGTAGACGGTGATGCCCGAGAAGACGGCCCCCATGACGA
AAGCCAGGATGACTGCAATGGCCAAGAGGGTGACGGGAACCAGCTGGTCGGGCCTTTGAGGTAACTT
304; ALL; chr5: 122461778-122463450; 5; chr5: 122462228-122462286; Unknown
CGGCCAAGGCTGGCGGCGGCAGGTACCCGGGTGCCCCGAGGGCCACCCGCCGCCCCGCTCTGGCGCATC
CATCAGTGGCCAGCTTTCACCGTGTCTGCCAGGCGGGACTCGCCAGGTGTCAGGCTCATGCCATAAGCCT
GACACTTGCGCGGGGTCGCCGTGGCTCCTCAGGGAAGCTGGGCCAAGGAGGCTGGGTCGCGCCGGCGGG
CGCCGAGGCCACCTTCTCGGGGCAGGCCATCCGCGCTGAGGCGCAGACACGGCGGTCCTCCAGGCCCATT
AATAACCCGGAGGGCGCTGCGATCCGACAGCGCAGTCGCCACAGGCTCTATTTCCCGTGGCCGCCTGCCT
CCTTCCAGCCCAGTTCGAGTGGAGGGATACTGGGCGCCCACTACCGCCCGGCCGGAGGGTGGGGGTCCC
TCTCGCGCAGGCTGCTTTGGAGAGTGTCGGAGAGAGACAGCTTTATCTACAGCTTCACCCATTGTATAGCA
CAACAGAATCGCATTTAGCCTGGAGAACAGCCGTCGGGGCAGGAGTTGTGCCTTCTCTAACAATTAGGCT
GATCGTTAAATTTGCTATTCCTTTCTTCCGGCGTCTAGGGAGAGCGTGCACACCAAACCCTCCAGAACAGC
ACCCCGGTCCCCCACCCCGCCCCACCTGTCCCCGCCCTGCTTAGTGCCTGGAGGGAGAACTGACTGGTCG
CTTGAGGGACCCCATTTCGGGCGCGCCCTTGGAGTCCTGGGGCTGCGGCTCCTGCTCTACCGGGCTGCAG
GCTTGCTCTGCCCCGTCCCGTGGCGTTTGGGAGGCAGTGAGGAAGCCTCCGAGTCTCTGGGTCGAAGGAA
GTGCGAATGGCACCCGCGATAGACTGGCCGTCTCCCCCACCCCGCCCCGTCTGGTGATTTTAAATCGTCTC
CTGTGTAATTGTAAAAAGAGGAAAGCTGAATACCAGACGACCAGTATAGAATCTCTTCGAGACAGCAGATT
GGGCAAGAGACGGGCTTTTTTTCGCAATACAAGGATAAACACATCCTGAAACTCCAGATAGAAACCTCAG
GAATGGGCGAGAGGGTCAGAAGGAACGAAGACAGTAGGGAAGAGAGAGAGAGAGACAGAGACAGAGGG
AGAGATGCAGAGAGACTGAAACGGGAGGAAGAAGCCTGGAACTGTCGGTTCCGTGGAGAGCGGACATGC
TATCTGCGCCCAGATCCGAAGGCTTTTGGGGAGCCTAG
311; ALL; chr5: 134390896-134393045; 5; PITX1; DOWNSTREAM
CACAGAAGAAAAGGCAACCCCAGGCATAAAGAGGCTCTCAGCAGCCCCTGCCCGAACGCTCCTGGCAGGC
AAGGGCCCCATAGCACCCTGGGGCCTCGAGGGTCACCGCAGACCCGGCCTGGGAAGAACCCGTAGAGTC
CCGCAGCCGCGGAGGGAGGGGGTTCTCGCTAAGGCGTCCCGCGGACAACGCCGAGAGGCACAGCTTAGC
GGGTGCGCACCGGACAGGCTCGCAACGCAGGACGGTGCCCTCATGGGAGCCAGGCGAGCAGGTCAAGAA
TGGTGGTGGGGAAGCGGGGTAGGCAGACCTCGGCGGGGGCTGCCTCGGCGCTCTGCTCCTACCCAAGGG
GCCCGGTTCCCTTTCTACCCACAGTTCCCTTTCTATCCGCCTCCCTCCTCAGCCAATGAAGCAGTCGGGGC
TCAGCAGTGCTTAGCACGCTCGGACTATGGTTTTAATAGACGTACATGGACAAGTCGATATAGACAGATTT
ATTACAGTCAGTCCAACATACACAGGGACGCTGTAAACAGGGGCGCGGCCGGAGAGCGGGTGTGCAAAGT
GGGCGCAGGGCCCTGGGGCCGCGCCCCTTGCTCTGCCGGCTCGACTCTTGCACGGCGGGCGGTGAGGAG
GGGGCTGTTCGCCCAGACAGAGGGCCACCTCCTAGCCCGGGAGCGAGCAGAGGGCCTGGGCCTGCAGCT
AAGCTCAAGGCTGGGGTGTTCTGAGATGGACCTCCCCCACCTCCCGCCAGGCCCGCACTGCCCGCTGTCG
CTCCGTGGCCTTAATATAGGGCTCCGGGGCGCGGGGCCAGCAGGCTCTACCAGGCGCGCCGGGGCCGTG
TGCGGCTCCACTGAGTGCCCGATCCTGGGCTGGGGGCACCGTCCCCCCAAACCCAACGCCCGCCCCAACA
CGGATCCGACTCGAGCTAAGGCGCTCTCGGCCGGGCCTGCTCGGAGAGGGCAACTTGGTTTGTACGGGGT
CGGGAAATCCTAGGCAAGTCCAGGCCCCGCACATCCAGTCCGCAGGCCCGGCCACTCAGTCCGGATCCAG
CGCGGCGGGGACGCGGGATACGAGGTCGTCCTCCCCGGCCGCTGGGCCTCGGCGCTCGCCTACCGCGCC
GCGTGCCCTCCGCGGAGTGGGCCTCCGGGGCCCGTGGGAACACACACACCACCCGCGCCATCCCGAGAG
AAATTGCAACTCATCCATTTTTTCGCGGCACTTTCTCCGACGT
314; ALL; chr5: 135442969-135443206; 5; chr5: 135443148-135443192; Unknown
CGCGCGGGACCGGAGGCGCACACCGGAGGGGAGGTGCCCCCACCAAAATTTAAGTGCGGCGCAACATGC
ACCACAGGTAGGGGCACTACCAGGGCAAAAAGACTTGGTGAATGCGAGGGCCGGGCCTATCAAAGGTGC
GTATGGTGGTACCAGAGCAAGGCGGAACAGCTGCTCAGTGGTCCGCAACCGGGTCAAGGGACAAGAAGA
CGATTCTGGATTGTAGGCCGCCCGAGAGCG
319; ALL; chr5: 174091287-174092335; 5; MSX2; DOWNSTREAM
CGGTGACTCGGAACAGAGGCAGAAAGGATGCGAGGACTTCTTGCTGCGTAAACAGCGCGGCGGGCAGAT
TGGCACCTGGCACCTACCAGGACTGGCGCTTCGTCCCGCGTTTCCATTGTGCCCGCACCACTTTGAAAGTG
GGCGCCGGAAACTCCGTTTTTCTTATGGGGCCGGGGTCGGGCAACGTGGTTCAGAGGTTTCACAAGCTCC
AGCACAGAAGTGATCCAAACCGAGGGGTCGGCTCGAAGTCGGAGGCTGATTTTTCTTGCTCAGTCGCTCC
GCCGGAGCTGAGCCGCTGGAACGACCCAAACCTACCTGAAAGCGCGTCTCTGCAGTCCCGCTGGACTTCT
CCGGCTCGAACTCCTAATCTCAGCCCGGAATCCAGCCATATTCATTTAAGATTGCGTTTTCCAAAGGCCAA
AGCCTTTCCCGGTTTCGTCATCAGCCGCCAGGTTGGGTCCCTAATTAGCCTGTCCACCGAGCTTCCTTCCC
GGCGCCGCTTGGACCCCGCAGCCCCGGGCGATCTCAGCCCGGGGGGGAATCCGGAGACGCCGGCTCCGG
GTTAAGACTCTGCTCGTCCCCAGGAGGACGGGGTCGCGATCCAGAGTGCGATCCGGAGAAAAGGGCTGCA
TCTTGCGTGGCTGGCGGGTTAGACTGGAATCCGTCTGGGGACTGCGCACCATCCCCATCGCTCCAGACGC
CGAAACAAAACCTGAGGCTCGGAGAGGGGAAAAAGAGTTGTTCAGGCTCGAACATACGCATCCCAGCCTC
ATAGGTGGATGGGGTTACCGAGCTGAGAACCAAGCCGAGGTCCGCGAAGCCGGGCCGCCCCCTTGCTCTG
GGCCTCCCTTCAAGCCTGCAGTCTGGGGATGGGTTCCGAGTCACCGCGGTCCGGGCCTCGGTCAGGCTTG
GTCGGGCACACAGGGCGTTTCAGAGGCCAGATGACAACCTGTGGCGGCAAAAGGACTCTCCCTCACCAGG
GACCCGCGAAGGCGCGCATTGCAAGATGTTAGCGTGCGGGCTTTAGATATCCTTGCGTCCG
324; ALL; chr6: 1549606-1560865; 6; FOXC1; PROMOTER
CGGGGTCCCACGCGGGCGGCGCGGTCTTCCCCAGGCCTCCTTCTCTGGAGACCCGGTTCCCAGGGGACGC
TGTGCGGGGACAGGCGGAGCCGGCCCTTGGAGCCCGGCGCGGGCAGAGGCGCCGCGGGACAACGCCTCC
GACGGCAGGGGGCGCTCGTAGCACGCGCAGTGCGCGGTGCGGGCGCCCAGGACGGCTGCCTGGCCCCGG
GTTCCCGAGGCGCGGGACCTGCCGGGGTGAGGTGCCCCCAGCCTGAGAGCCCCAGCTGGGTCGGCCAAG
GGGCCTCCGGGCTTCCACATCGTCCCTTTTTCTGCTGACGCTCGCGGGGAAGCGGCGGGAAGCCTGTGAG
GGGCGGCCTGGGAGCAGACGGACCACCAGGTCACCGGCGCGCGCTGCCAGGCCCGACCCACTCGCGAGG
ACCAGCGGTTCCCGGAGGCGTCGGCCCTCAGGTCCTCGGGGGAGGCCGGCTGCACCGAGCCGGGTGTCG
GCCTTGTCCCTGTCCTGAGAGGTGCAAACACCGGCCCCGGCCCAGGCCCCGGGGCTCCTGCCCAGAAGGC
TCAGAGCTGGGGGCCGACCGCGCCTTACCCGCAGGAGGCCCGGCGGTGCGTCCGCGTTGGTGCCACTCC
CCGGCCGGGGTGAGGGACGTCGGAAGGAAGGTCCCAGGGCGCAGGGTCCGCGAAGGGAGCACTCGGAA
GGAAGGCTGGCTGCGGCCCCGGCGCCTGGGTCCGCTGCGGCGCCGGGCCGGAGACCTGGGAACAGCCAG
CCACCTGCAAGGTTGCAGCCCACCTCACCCCGCCGGCGGCTCCGGGCTGTCTGTGGGTCTGTCTCACGGG
GCAAAGCCTTTCTTCCCACACCCACAGCCAAGGCGCGTCCGTGCAGGGGCACACGCCTTCTGCTCCAGCC
CCAGGAAGGCGCTTTCGCCCTGCAGTCCTCCGACGGCCGGCTCCGCCGCACCGCGCACCCTGGCTCCGGC
AGACTCTGGGGCCTGGGGACTCGCCCACCCTGCGCGGCGCGCCCCCCACATGAGCCGAGGTTGGGAGGC
TGCGGGGCCTCTGTCCTCCCAGGCCGTGGAGTGCGGCGGCGCTCTGAGTCCGCTGGGGACCTGGATGGA
GAGAAACTGGGGCTCGTTCGCGCACACATGCACCATTTGTTCTTTCCGATCATCTATCCCTTTACGAATTT
TATTTTTATTCCGGATTGTTAATGCAAGACGACAGTTGAATCTCCA
339; ALL; chr7: 1481682-1482268; 7; chr7: 001481829-001481873; Unknown
CGGCCTGCGGTGGGGAAGCGGGTACGGGAGGCCCAGCTCTCCCCACCAGGGTCACTGGAGAGGAGCAGA
CGCAGCCGTCCGCCAAGACCCGGGCACGAGTCCCCAGCAGCTGTCACTGCCCCAAACTAACGTGACCCCA
CGTCCACCAGCAGGTGAACAGATAAACCAACGGCCGATCCACACAATGGCAGGCCACCCAGTGCCCACAA
CACCACGACTCTCCAGACTGTGCGAGCAGAGCACCCGCAAGCTCCCTCGGTATAAACTCAACGCAGACAA
ACCCACAGGGCCACAGGGCGGCGCGGACTGGGAAGGGGCAAGAGGGGTAGCCGGCGATGGCCATGTACA
CTGTGGCCTCCGCCCTCCCTCCCTGCCCGGCCAGGGCACCTGGGACGGCGGGGGGAGCGGCAGAGTTGC
GCCCTCACCTTGCAGACGCTGCTGCTGGCAGCCCCTTCGCTGTGCAGTAGGACCTCAGGCACGGGCACCC
GCAGCTCCGGCCGCTGTAGGTAGAGCTGCAGGAGAAGGTCTCGGCAGCCCTGCCCAGCACGCTGGAAGA
GGTGGAGCAGGGCTCACCAGGCGGACG
340; ALL; chr7: 2082782-2083345; 7; MAD1L1; INSIDE
AACACAGTTATGACACAGTGAGCCCACAGCACAGTTAGCCTGCAGCACAGTGAGCCCGAGACACAGGTAT
GACACAGCGAGCACATGGCATGGTGACCCTGAGACAGGGTTACGACTTGGTGAGCCCCAACATGGTGAGC
CCAAGACGGTTACGACATGGTGAGCTCACGGCACAGTGAGCCTGAGATGGTTACGACACGATGAGCCCGC
AGCACGGTCAGCCTGAGACGGTTACAACATGGTGAGCCTGTGGCACGGTGAGCCAAGACAGGGTTACGAC
ATAGTGAGCCCACAGCATGGTCAGCCCGAGACAGTTATGGCACAGTGAGCCCGCGGCACGGTGAGCCCGC
AGCATGGTGAGCCCGAGACGGTTATGACACAGTGAGCTCACGGCACGGTAGCCCGAGACAGAGTTACGAC
TTGGTGAGCCCGCGGCATGGTGAGCCCAAGACAGAGTTACGACTTGGTGAGCCCGCGGCATGGTGAGCCC
GAGATGGTTACGACATGGTGAGCTCGCAGCACGGTGAGCCTGCCATGGCCTCAAGGGTTAAGATGTAAAC
345; ALL; chr7: 2724511-2724848; 7; AMZ1; DOWNSTREAM
CTTCTCAGCAAAGGCCAACACGTCTTTCTCGAGTCCAAGACCATCTCCCGTTCAAGGGCCCTCACCGCGCT
TTGTGAGTCTGTCTCGTGGGCCTCCTTCAGTGGTCTGTGACCAGCGGGAATGAATGGGACGTGTTTTGTTC
AGCCCTGACTCTTGGACGCTGGTGGCAGCCGCGGGCGCCCACTCACCTGGCACGTGGACGAAGGTGATGA
GCGCGGCTGACGGCTCCCGGGGGCAGTGTGGGGTCCAGTCTGAAGCCGACGCCCTCTCGGTCAGGCTTTC
AGCAGCAGAAGGCAGTGGACTCTTCACCATTTCTTCCAACACTTTCTCACGTAG
349; ALL; chr7: 8449587-8450236; 7; NXPH1; INSIDE
AAACTGAGGCAACCAACTTATTCGCAAGAGTAAAACCCTATGGGGAGAAGCGATTCCTGCCCCTCTTCCCC
CGGCGAGGAACACGGCTGGAGCCACCCAGGCGCCTTCCAGGCTAAGGCGCCTTTAGGGCGCGCAGGGGT
GAGGGAGAGGGTGGGGAGAGTCCTAATTATTATGAATTTCTAAAGGCGCAGTAATTATTCACGGGGAGCA
GGACAAACCATGGCTAGGCAGGGAAATCGATATATTTGCTATCGAAAGTTCCTGCTCGCCTTTAATGCAGA
CGAATGGGGGATGCAGCCTCATTATTTTCCGTGGTTAGGCTCGCCAGCGTGGGGCCTGATGCAGCGTGAA
ATCTATCATCATTAGACCCGGGATGGAGCGGCGGGGGGGAGTTTCTCTTACTTACCAAACCGCAACAACA
AACAAACAACGACGAACAACCGCCCCCTACAAACACTCATTCTCACACAACGTTGCCCTACCTCCCTCGCC
GCTTGCCCTGGCCGCTGTTGCACACTCCCCTGGGGGCTGTCTGACGCCCTAGAGCAGACACTGCGGTCAC
TTAAAGTGCGCCCAGTTCCTCCACCGCAGCGGTCACACCGTTGATTTGATCCAGAAATAAGACGGATAGTA
CCGAGCGTTGGCG
354; ALL; chr7: 27164708-27165039; 7; HOXA7; PROMOTER
CGCCGCCGCCGTCTGTCTAGACTCAAGCGACTGAAGGGGCCAACAGAGCTGGTGTTTAAAGTAGAACCTG
CCCAGTCCAACAGCCCGAGCAGGGAGCGATTTCGGGGATCGCGGGAAGGAACGCACTCGCCAAGGGAGG
GCCGGGTGCCCTCGCCACCGGCTCATTCCTGCTCCGGTTTTGCCCGATGCGCGTCCAGGAGGTTCTGGCA
GGACGCACTGCCCCTCTGCCCCGGCCAAGGAGGATGCGGATACTGCCCGCAAGGTTCGGCCTTTATGGAC
CCAAGTCAGCCAACTGGGCCGAGTCCTGCGGACACCGAAACCTCCCTTTCG
358; ALL; chr7: 27251165-27252762; 7; EVX1; INSIDE
CGCCTGTGCTCTGGACTCGCTGTGCAGGGTCCGGCTCCGAGGCGCTGGTCGGCAGTCCGAACGGAGGGA
GCGAGACCCCCAAGAGCAACGGCGGCAGTGGTGGGGGCGGCTCGCAAGGCACCCTGGCTGCAGCGCCAG
TGACCAGATGCGTCGTTACCGCACCGCCTTCACCCGAGAGCAGATTGCGCGGCTGGAGAAGGAATTCTAC
CGGGAGAACTACGTATCCAGGCCGCGGAGATGTGAGCTGGCGGCCGCCCTAAACCGCCGGAAACCACCAT
CAAGGTATGCGGGGTCCAGGCTGGGGAGGCGGGTGTGCACCTATTTAGCGGGAAGTAAATGCCAACTGCC
AACTCCCTGAAACGCAGGCCAGGAATCTGGGCCTGGGGTCTCCCTGCCCGGGCGTGCAGATTGACCCTCG
TGACAGCTCCTAGGCAGGCATTGCTGCCATGTGGCTGACTCTGTCCCTTTCCTGGTTAAATAGACAAGGGG
TGGGCGTGGGGGAAGGGGATAGAGTGCCTGTGCGGGTGACAAGGAATTTCTGGGGACACGCTCTCTGCG
GCCGCAGACCAATTGAGTCCATGTCCTTTCACTGCTCCTCCCATACACACACTGGCCTCTGGCACCCCGGG
GGCCTGGCCACCTGGGCAGAAGGAAGGAGGGAGCGGGCTGGATCACTCCCCAAACCTCTCTCGGAGGGA
TTCCAGCTCCAGGTGGTGGTGGTGGGGTCGGTCTCTACCCGGCTGGTGTCTGCTTTGGCTGTTCCTGCCC
TGCGAACACTGTCCCCGGAGCGGGACCAGACTACTGGCCCTGAGCATCGGGCCAAGTCCAGCTACTGAAC
CTGCTCCGCTCCTCTCCCCAGGTGTGGTTCCAGAACCGGCGCATGAAGGACAAGCGGCAGCGCCTGGCCA
TGACGTGGCCGCACCCGGCGGACCCCGCCTTCTACCTTACATGATGAGCCATGCGGCGGCCGCGGGCGGC
CTGCCCTACCCCTTCCCATCGCACCTGCCCCTGCCCTACTACTCGCCGGTGGGCCTGGGCGCCGCATCCG
CCGCCTCCGCCGCCGCCTCGCCCTTCAGCGGTCGCTGCGCCCGCTCGACACGTTCCGCGTGCTGTCGCAG
CCCTACCCGCGGCCCGAACTGCTGTGCGCCTTCCGCCACCCGCCGCTCTACCCCGGGCCCGCGCACGGAC
TGGGCGCCTCTGCCGGCGGCCCCTGCTCTGCCTCGCCT
359; ALL; chr7: 32768010-32768497; 7; chr7: 032768257-032768301; Unknown
CGGACTTGTCCCCGCAGCCCTTGCGGACCTCCTGGTCGTCATGGCGACTGTGAAATGTGGGGTGGGGAGC
ATGCGTTCGAAGCCATTTGCGCGGGCAGTCCCTGCGTGTCCCCCCACGTGCTCCCCACACTCGCAGGACC
CCCGCCTCCGAGCTTCCCTGAGCGTGCAGCTTCCAGTGAGGGCAGCCCCACGCACAGCCCCCCACACCCT
CCCCAACGCCTTCAGCCCCCGGTGCGCGTAGTCCCCAAGCCCACACGTGCACTTCCACCTTGCGGCAGCT
GCACGTACAGCCCCCCACACGCTCCCAGCCCCACTGGCGCAGAACCCATCACCGCTCGCCCTTCACGCGC
TTCACTGGGAGTGCAGCCCCCACCCCGAGCGCGCAGCTCCACGCAGCCTTCCACACTCTCCCCAGCGCCT
GCAGCACCCCCAGTGCGCACAGCTCTGCCAGTCGCTTCCCCGCGTGCCGCCCCTGCACCACTTCG
362; ALL; chr7: 55040457-55041024; 7; chr7: 055040965-055041024; Unknown
CGAGCACGGCCTCGGAGGCTGAGAGGCCTGGGAGGCAGGGCCGCGTCCTGCGGGCTCCACGAGAGCCCT
GTGAAATGCCAGTCAGATCCTGGCCCAGTGCCCCAGGTCCTCCCGCAGCCTCGGCAAACCCTCCCCCGGC
GCTGGAAACCTTCCCCTGCCAGGCGCAGAAGGCCGCGCGCAAGCACGCAGCTCACAGTCACCGCCACCTG
CTCTGAAACCCCAGGTTCAGCGCAGGATCAGAGTCCCCCATCCCCACCCCACGCAAGGGACGCAGGATTG
ACAGCGACCCTGAAGAAATGCAGTCGAGAGCTATTGTGAAAGGGCGCTGGCCCGGAGGCCCCCCAGCCC
GCGCAGGACAGGCCAGTTAATCGCCTTGGTCCCAGGCCCCTATTAGCGTGTCATCTGCGACAGCAGGACA
CGCCTTCCCATGCCAGCCGCTTTGGGGCCCGTGCGGCCCTTTTTCCCTCGCAGCTGCTGCAACAAATAGCA
GTTCTTTTGAGGGAAGGAACAGTGTGGTCCTCAAAGTTCATAATGAAAATCTTGGAGAAAAGTCATAGTTG
CTAA
364; ALL; chr7: 96488158-96489591; 7; DLX5; INSIDE
CGAGCGGGACGAGCCCTGGGGCTCCCACACCGCTGGAGACTGCGGCGAGTTACACGCCATTGGGTCGCT
GGAGCTGGGACTGTGCTCCGGGGGCATCTCCCCGTTTTTCATGATCTTCTTGATCTTGATCTTTTGTTCTG
AAACCAGATTTTCACCTGAGTTGGGGAACAAAGGCACACGTTACCGGGACACTCAGAGGTCGCCCGCGCC
TTCCCCGGGGCGGCGACTGGAGGCATCTTCGGACCTCTGGGCGGCCCAGCCCTCCTGGCGTCTCCCCGCC
GCTTGCGGCCTACCGCCAAGAAGCTATGCCTTAGGCAAACCATGGAGCTCTGGCCCCAGAGGGCGCCCTG
GCCGGCTCGGGGCGCCCCGGCCCAGCGAGGCCACGACCCCAAGGCTTGTTTTTGTTTGGGCTGGGGGTG
GGGGACGCCAGCGCGGCGGGTGTGCGCCCGAGTGTCCTCGGCGGCGGCGCGCCTCGTGTAAGCCTGCGC
AGGACGCGCGGAACGCGGCGAAGGTCTCCAAAACAATCGCGCGAGCCGGCGGGGAAGGGGCGTGGGGC
GGGCTACGCGCGCCTGTGGTCAGAAAAAGGAGCGAGCTCCCAACCTCCCGTCCTACTCCCTTCACTCCCT
CTGCAGCTCAGAGAGGCCAGAATCTGACTGCAGCTCTTGGCGGCGCTCGAACATTCTTTATGCTTCCGTAG
GCCCCAGCTGGGTTGGAGGAGTAAAAGGAATGGGACAATCCAGGAAGACTTCTCACGTACAATAGCGCCC
CCCACCTCGCGACCCTTCGGTGGCCGTGGCCTGAAGCTCCGTAGGCTCAGGGCACGACCCTTCAGTTTCT
CCGCTCCAGGCGACGTTCTCAGCCTTTTCTTAGCCTGAGACCACCGCGAGAACACCAGGCCTTGCTCACCC
CCGAGGAGGCTCTACATTGTTAAGAAAACCAGATACTGCTCTGGGCTGCCTAGGCCGCCCTAGAAATAAC
CCTCCGCTTGCTTTCAACCCGCGAAATTGGCCCCACAGCTCCGGAGGCCCGCTACGGGGTGGGGGCGGGG
GGCGCGGTTAGTGGGAGGTATCTCCAGACCGTGATGAATACCATCCCCACCGTCTCAAGGCCTGACTCAC
CGAGTTAAAGCATAGGGGCTGATGTCTTTGGGTCTGTTAGTTTCTCACGGGTACTGTCAAAACAGCTCCAG
TCCCATCGAGACTGAACCGCGCGACCAACCAGACGTG
369; ALL; chr7: 155266364-155266696; 7; RBM33; INSIDE
CGATTCAAAGATGCCGGCGTCCCGCAGTGTGCGGTTCGTGCCCTTAACCACCCGCTTCTTTGTTTCCCGCC
CCTCTGCTTTCGCAGGAGCTCTTGTGCTTGAGTTCAGTGTTAGTGGTAGCGTGGCTACTCCACTTGGAGGT
GGCGGCCGTCTGACCGTGTGTTACTGCTTTGCCGACGGGGCCTCCCGGCCCTGATGCGTGTACACTCTGC
GGGCTGCACCGGGTGGCTCTGGTTGGGGGCGAAGCTGTGTTGACTGGGAGACGTTGGAAATTGAGACAT
GGAGAGATGACGGGAGTGCGTTTCTCTGGGTTTGATCTCCATCCTGTTTT
371; ALL; chr7: 155288454-155292175; 7; SHH; INSIDE
CGCGGTGGCCCCCGCACCCGGAGCGTCGGCAGCACCTGGAGCGGTTAGGGCTACTCTGCCGCCGCCGCC
CCCGCGGTCCCCGCCGCCGCTGTCCCCGCCGCGGTCCGTGCGCGCGGGCGCCAGTGCACCAGGAGCGCG
TGCGCCAGGCGGAAGGGCGCGAAGGCCCGGTGCGCCCAGCTGTGCTCCTCGATGACCGCGTAGCACGAG
GCCAGCACCCGGTTGATGAGAATGGTGCCCTGGGCCGTGAGCGGCGCGTAGGCGCCGCGGCCTCCTCGC
TTAGGGTCACGCTGTGCACAGCGGCGGGCAGGAGCCGGCGGTCCCCGTCACGCTCGGCCACCACGTACA
CGCGCTGGCCCGGGCGCACGCGGCTGGCGAACAGCGCCCGAGGCCCCAGTGCGCCCCGGAAGGCGGCCC
CGAGCCCGAGGACGCCTCGGGCTCCCCGGTGGCCGAGTCGTTGTGCGGCGCCACAAAGAGCAGGTGCGC
GGCGGTGAGCAGCAGGCGCTCGCGCGGCTCCCGCGTCTCGATCACGTAGAAGCCTTCTTGGCGCCGTCGT
CGCGGTCCAGGAAAGTGAGGAAGTCGCTGTAGAGCAGCCGGCCCTGGTCGTCCGCCGCCAGCACGCGGT
CCCCGGGGCTCAGGTCCTTCACCAGCTTGGTGCCGCCCTGCTCCAGGTGACCGTGGCCGAGCCCGGGAAG
CAGCCTCCCGATTTGGCCGCCACCGAGTTCTCTGCGGGTGAGGAGAAGGGAAAGAAGAGAGGACAGGGC
ATTGAGTTCCGAGAGGGAGGCGCGTCTCGGGGAGGAGGGCGCACGCTGGTGCCCGCGCTCCTAGGCCAG
GGGTGCGCAAGGCGCGGGGCGGGGCGATTGATTCCAGGCGGGTCCCGCACACACCTCCCTCCCCCAACC
CCACTGCCCCAGGGACAGGATTCCGACACATTCCTTAACGACTCCTAAGTCTGGGCTGGCGGTCACAGAG
GTTGGCTGGCGTTTCCTGCAGAGGCCGGTGACACTCTTTCCTTCCGCCTTCCTCCAACCCCACCCCCAGCT
CCGCACACACCCGGCCTCGCCGCGAATCCATCCAGAGGGGTTTGCTCTGCACTTGGATTCCTCAGGAAGC
CTCCTTGAGCTCCCGCGGGCGCCGGGCGCACCCTCCTTCCCTCCCGCCCCGGCGCGGGGCGCGGCGCCT
GCTCGCGCACTCAGCACCCGGGCTGCGCGGCGGAAACCCTGGCCCGC
390; ALL; chr8: 142288380-142288718; 8; SLC45A4; DOWNSTREAM
CGCACGGCCTCCTCGTCCCTCTCGGGCAAGGCTATCAGCCAGAGCACCTCCCCTTTGACACTGACCGGCG
TCCCCAGCCCCGCCTTGTTACTGCATCCGTCTGAGGTACAAGGTTAGAAGCCACAGAACCCGAGCTGCAG
CCTGACCCACACAAGCTGCGGGCGCAATGGCGCTTTGCAGACAAGACAGCCTGCCCGTCTGCCCTTCTTC
TCGGCTTCCCTTAAGACACAAGGTGACGACACGGACGGTTTCAAGTGAGTGCATCTGGAAATAATCTCAGT
GCAGGGGAGGGGTTGAGGCCAAAGATGTCGTGACCTGGTCCCCGCTGTGGCCAGGC
402; ALL; chrX: 39749470-39754050; X; chrX: 039752648-039752692; Unknown
CGAGGTATAAAGACCAACGCACGACGGGCGCCGGGGCGCCGTCACCTGCCTGGGTTAACAGTTCCTGCCG
CGGGGGCAGGGAGAAAGGCGCTAGAGGGGCGCGGGGTGCCGGCGGGGCCGAGCCCGGGCGCGGGCGAG
CCCTGGGTGCCAGGCCCTGCGCCGCACGCCACTCTCGCAGCGCTGCCGCCGGGAAAGTGCCGGCGCTGG
CTCTCCCTCCCCTCCCGGGAATAGCGGGCGCAGGCACGCACATCCACACACATCCAACACACACACACAC
CGCACACTCACACACCCGGGTGGCCGCGCGGGGCTCCGAGCCGCGCAGGCCTCCTTGGCAGACATCTTCC
TGTGGGAGGATTTCAAACGAGCCGTGAAAGCCAGAAACTACACGGGTTACAACTCCGGAATCCCTGGCCG
GCCTCGGCCTCCCTCCCCACCTCCGGCCCGGCCCCCTCCGTTCGGCCCGTGGCCAGGAGCCCCACCAAAG
GACAAAGCTCACACGCCGAAAGCGCGGGGAGATCCGGGGGCGCAGAGATGCCCCGACGGCCCTTCTACC
TTCTGACCCTGGGACCCACGGCCAAGTGCCGCGCAGCCGAGGTCGGCCTTGCTGATCTGTGGTGGCCCAG
GGCGACCCGAAGCGCACCGGCTTCAGGGTGCGCCCTGGCCAGGGCTGGGGTGGAGGGTCACATAAGCCA
CCTGGCATCCGAGGGTGGCCGCCTCGCCCCCTCAACGCCGCTCTCCAGGGAAGGAGGCGGCGGGGTCAC
CAGGGCGCAGCTGACAGCCCCAGGCCCCGGCCAGGGCGCACCCAAAGAAGAGGGAGGCTGCTGCCTGAA
CTGGCCTGGGGGCAGAGGGAAGTGGGCCCCGCGCTGTGGAAGGCCCCAGGCTGGAGCGCCGGGGACAGC
TGTCCAAGCGGCGAGGGCTAGGAGTGGCCTCGCCTAGCGCTAGCCGGCCAGGCCCTGGAGGTGCTCCGC
GCCTTCTCGGCCAAAAGCCAGCTCCGCGCCGCTGGCGGAGTGGGAGGGAGGCGGCCAGGCGAGCGCCCC
GCCTTCGTCGCCCGCGGTCACAGGGGCAATTACACTCCTGCTGCAGACGGTTACCAGCTCGCCCGCGCAT
CCCTCTCTCGGCTCCCCTCTCCTCCCCTCTCCTCTCCTCCCCTCCCCTCCTCCGCGGAACTGCTGGCTCCA
TATTAGCGAGGGTGCCCTGGCAGCGCGACCGAGGCAACTACCCCT
TABLE 4
CpG islands hypermethylated in NMI-BC FGFR3 wt vs mut.
Provided for each are: ID; Comparision; Coordinates of selected regions
containing relevant CpG islands based on Homo sapiens full genome as
provided by UCSC (hg18, March 2006); Chromosome; GeneName; Location
relative to gene Sequence.
4; SW vs SM; chr1: 2211959-2212429; 1; SKI; INSIDE
TAGGCAGGAGGAGGAGGAGGAAGAGGGCACCTGCTGAGATACTTCACTGGTCTGAGGGCCCCTTCTGCCC
CAGCTAGCGCTTGGGTGAGGGTTGGGCTTGCGGAGCCGTCCTGTAAAGCCGGGGATGCAGGACGCATTGT
CACCCCCTCCTGCCGCTCTTACGAAACACTCTTAATTGAGTCCGATTCTTGGTGAATCAGCCTTCCAAGAA
CCGCGACCGCAGCATCCTGTGCCGCTTCTGTGTTCCGCATTTTTCTCTTTCTGCAGCGTTTCCTCTCATTCT
GGATGGAAAGCCTGTTTGTCTCCCTCAATCTTTGGCGAGGGTGGCAGGCAGCCAGGCGGCCATTACGGGC
CGCGCCTCCCACCAGCCAGTCGCTGGCAGGAGCGTCCGGGGAGGGAGCAGACCCCGTTCACCCTCACCCC
AGAACTGAAGCAGCGAGGGGACCCAGACGAGCTGGAATGCAGGCG
5; SW vs SM; chr1: 2226303-2228929; 1; SKI; INSIDE
CGCGCTCCGCCAGCAAGACCTGGCGTCTGCAAAACACAGGCGTGAGGGGCGTGCTTACTAATGCCTGGTG
TTCCAGAAGGCGGCTCCCGCCAGGCCTCCCGAGTAGGAAGGAGAGGGCTCGGCCCGCCAGACACACACA
CACCCACCTGCACACGCTGCTTCTCTGGGCTCTGCCTCACGGTTCTCACGCTGCAGCTCCGGTCTCGCGCC
TCCTTTTACGTTGTTTAGGTTTCTTTCTGACATGACTGAGGGAAGTGCGGTTCACAGGCAGAGCTGCCTGG
GGAGAGAGGTGGCAGGCGGCCCGTTGTTCACCGGGCCCCGGCCTCGCTAAATTCACACCTCGGCGGCGTC
TGGCAGCTTCCGCGGCGTGGGCTTTAGCACAACACAACCCCGTCGGCCCTCAGAGCTGCAGGGTTGCCGA
CGTGCCCTCCTGCGCGTGCCAGTCCCTCGCCCCAGCCGTCCCCCGCCACTGTTGTCCTTGATTCTGGTTGG
AGGTGTGATTTCCCACATACATATTCATGTGGTGTGTTTGCAGCGTGGGGTGTGAGTCACACGGATATTTT
AATGGGGAGAGTGGGGGGGCTTGCGGAGGCGCCGGGCGGATGGACGTGTCCATCTGGCTCGTGGGGAGA
CCCGGGGCCCTCAGATGGTGCGATGTCTGAGGCTGCCCTCCTCACATTGATGGGAGCCAGGGCCTACTTG
GCTTGCTGCCCCCAAGGGGAACGTGGCCCTAGATACCGGGGGAGGCCCCGCCGCAGCCTCAAGTGACTG
ACTCAGGCCCCCAGGTTAGCACAGCTGCCACAGGCCTGGCGGAAACTCCGGATGGGGGTCTGAAAAGCCT
TTGTGGGGTCGGGGCACCACACGGGTTGGGCTGATGGCGCGCTGGGGGCGGGGCTCCAGGGCACATTGT
CAGATAGATGACCCCACGGGGTGGGCTGAGGACTGCTGGTCAGGTGAGGGGTGTGCTGGGACCGGCTGG
GCAGTGACCCCGAGCCGCCTCCGGCCCCCAGGAGCTGGAGTTCCTACGCGTGGCCAAGAAGGAGAAGCT
GCGGGAGGCCACGGAGGCCAAGCGTAACCTGCGGAAGGAGATCGAGCGTCTCCGCGCCGAGAACGAGAA
AAGATGAAAGAGGCCAACGAGTCACGGCTGCGCCTGAAGCGGGAGCTGGAGCAGGCGCGGCAGGCCCGG
GTGTGCGACAAGGGCTGCGAGGCGGGCCGCCTGCGCGCCAAGTACTCGGCCCAGGTATGCGGGTGGGGA
GACTGAGGCACGCAGCACGGTGGGCGTGAGCCGCCGTGGGCCCCGGTGGCCAGTCCTGCCCAGCCGGAA
19; SW vs SM; chr1: 92718496-92725197; 1; GFI1; INSIDE
CGAGTGCACGGCTTTGTGCTGCTCCAGGCTCACCGCGTGCCCGAAGGTCTTGCCGCACATCTCGCAGGCA
AAGGGTCTGGTACCGCTGTGGGACCTGCGCACGTGCACCTCGAGCCCGTGCGGCGTGAGAACACCTAAGG
CGGGTGGGGCCAGAGAGAAGGCCGCTGAGAGGGGCCGCGGGGCGCAGGCGAGGCGCGGGTAGGGGAAG
CGGGCGCACGGCAGGCGAGGTGGTGAGCTCGGGAGCCTCACCTTGCTGCACTTGATGCACTTGTAGGAGC
CGCCGCCCAGCAGCGGCGGGTGCACAGCAGCTCCGACTCCACCTTGACGCCAGCGCCCTTGTCTGCGTGC
AGCCCGTGGCCACGCTCGGGGTACAGCAAGCCCGCCGCTGCCGTGGGCCTCTCATACAGCCCGGCTGCCG
CAGACCCGAAGTCGCCGTAGAGCCCTAGGCCAGGGCCAGGGTGGCACCGGCCCCTGCGCTGCAGCTCCC
TGGCGCCCCGGCCCCCGCGCCGCCGGCAGCCCGCTTCGGGCCGTACAGCGCGGCCGGGTGGCCAGGCTC
CGGGGCGGGTTCGCAGAAGAGGCCCAGGCCAGCGCCACGCTCCAGGGCCCCACACGGTCGGTAGCTTGC
ACCAGGTGCCGCAGGTCAGAACCCGCCAGGCCGCTCCATGAGTACGGTTTGAAAGGCAGGGGGAAGGGC
TGGGCTTCGTCCAGCGATGGGCACATTGACTTCTCCGAGGCTGTGGAGGCACAAGGGGAGCGTCCGGTCA
GGCTTCAGACGGCAGAGCGGAGGCGCCGGGCTGCGGCTGCGAGCGTGGCGTGTTCGCGGACTGCGGGGC
ACCCAGCGCTTGTAGAACACTGCGTGCGCCAGGTGCCAGGCTCGCCCCAGGGTAAAACGTGGCCCGGGCC
CTGGGGCCTCGCAGGCCACTATAGGAGGCAGAACAGTAAACAGATCATTAAAAGACCTCGGGAGAGGAGG
TCGTAAATTCTGTGCGAGTGCAGCGGAGGCGCTCGGCGTTCCGAGGATCTTTTCTGGCTGGACCCGCGCA
CCTGGAGATCCTACAGGGAAGGGCGCATCTATAAATGCCCGTAGTTGAGCTGTTAAGAAGGAGAAGGTGG
CGGCGTTCGGCCCCTCACAGCACTCAAGGGCGGAAGGGTCCAGCCACCAGCGCAGGCACTCTCCCAGCCC
CTACATGTTCCCATTCAATTCTTTTTCTTCCCAGAATCCAAGAGGAAGGAGGGAGAAGGTCCATAAATGCG
GCCCCGAACTACCCGAAAGGCTGCTGTCGAATAAACCCGAAGGTATTAAGATTTCACGAAGTTAAGTGCC
24; SW vs SM; chr1: 163590111-163590435; 1; LMX1A; INSIDE
CGAGAGGCCCGGCCACCGGCTCGGGAGCTGGGCCGGTCGCTTTGGGAGCGGATGAGGAAGGTTAGGAGA
AGCAGCGAGATAGATCCCAATTTTACAATTCTATTTTCTTTCGGTAGGGTCTCGGCGTCTGGGCCACGTTG
AGAGCGAACGTGGGCCGAGCGGAGGACACAGAGTAAAAAGCGACGCCCGCTGTATACATAAATCCGCACC
CGCTGCCCGCCCGGGTACTGCCTGCTCTGGCTTCCGCTCTCTTCCGAGGCTGGGCAAGTCCAAAAGTTCC
CGAAAGGGGGGTCAAAGAGGGGCGCTCAGTGCACGTGATTTCG
29; SW vs SM; chr1: 219134035-219134808; 1; HLX1; DOWNSTREAM
TTCTTCCCTCTTTACTCCATTCCCTAACTCCTGCCTCGTAGGCAGCGGTGGGGAGCCGCAGGCTGCTCCCC
GAGTCCCAACGCTACTAGGGTGCTGTAACAGTGATGAGGCGGCGTTGCAGTCTGGCAGGCGCTGCAGCGG
GCACCAGCTACGTTTTGCTGTCGGCGGCAGTTACCCGGACGCAAGTTAAGGGGTAGGCGCGCAGAGGCG
GTTGGAGGCGGGCGGCCGGCCCCTGACCTCGGAGAGCTGCGCCGAGCAGGGCGGAAAATTTATGGTCTG
TGTACACTTTCTGCTCCAGAGCCCCGCGCACCAGAAGGATGGGGCCCTGCGAGCGCGCCCCAGGCCGCGA
GCTGGGGCCGCAGGCGCCACGGCCATGTATAGTGCCCACCCGACTCTGTTCTGCAGCGCTGTGGTCATAA
ACCTTCCCTTAGAGGGCGCGGCTGTAAACGAAAGTCCGGCGAGAGGTGGATGCAGGCCTTGCCGCCCGGA
CCCTCAGGTATAATTCTGGAAACTTGCACGGAAGCCTGGGTCCCGCCATCTTCCCTGTTGTGGTGGGGTAA
GAGGATAGTTTATACTGGCTGTTTGGAATCCCGCGCGGTGGATGCAAGGTGGGATTCCAGCCAGCGACGC
GCCGCGTGGCCGGGAGTGCAGACAGGTCACCGGTCCCCGGGTGTCTGGACCGCGCCGCTTCCTACTGGG
CTTACTTCGGGATCTAGACTTCGGCCTCCGTCCTTGCAAGGGCCCAGATTTGATTCCGGTTCGTCGAGGCG
35; SW vs SM; chr10: 845627-845967; 10; LARP5; INSIDE
CGAAACCCTCGAGGAGCGACCACATGACCCCCGCGCTGTGAGCTGCTGGCGGCCAGCGCCCTCGCCTCGA
TTGTCTGCAGCCCTGTAGTGGGCCGCGAGGCACGCAAGCCGCAACTACAGCTCGCCACGGGGCACACAGA
CAGGCATGCACCACCACTACCCGTCGCCCGGATACACTGAACTGGTTTTGAAGCCTGAACTGCAGAGATC
CTAATATAGCAACGCAGGACGTTTACGGCCACCCGCCAGTGACAGCCGGTGATGTGATGACAGGAGGGCC
TGGGTGAAAATGCAAGACACTCACTCTCAGAGAACGACGACTCCACTTGAAATTCATGT
38; SW vs SM; chr10: 3150889-3151107; 10; PFKP; INSIDE
CGGCCGGGTGGGGACCGGCGTGGCGTCCTGCGGACCGCGTGGAGTTTGGGGTGTCTGACATCGTTCTCC
ACGTGGCTATTTTCAGCGTTCTCCCGGGGAAGTACTTGGAAGAGATCGCCACACAGATCGCACGCACAGC
ATCAACGCGCTGCTGATCATCGGTGGATTCGAGGTACGTTACCGTTTCTCTCTTGCCGGTCTTGCAGGTGT
GAGCCGCG
42; SW vs SM; chr10: 7489383-7495345; 10; SFMBT2; INSIDE
CGGCAACCGAGCCAGATCCAAGAGGGGTCGGCCTCGTCTAAATTGGTTTCCCACCAATGGCCTCGGATCA
GCCGCGGCTGTGCTGCGGGAGCCCTCAGGACGCGGCTGGGGTTGGTGCGCGGGGCCCGGAACCCCAAAC
CCGGCTCGGTTCGGCAAGGTTCAGGGAGACAAGGTAGAGAAGGCTGGGGTGAGCGAGAAGTCGGGCGGC
CGATCGTCAGGGCCACGAGCCTCGCCTTGCCTTCTTGGAATCCCACCCAACTTTAAAGGCCCAAAGATCCT
GAAAATTCCGAAACGAAACTGCGAGCTGGTCTCCAGAAGTTTGAGAACGGTCTCCCAGGCTTTCCAGCGT
CGTCCCGGGATTCTCGGACACCACAAACGCCATCAACCACGAGCACCGGTGTCCGTGGCTATTGCCCCGA
ATGGTCCCCATCCGCGTCCCCGGGAACTCCCTCGGCTTTCGCGCATCCAGGTCCCCAGCCCCAGCTACTG
GTGCGCCCCGAGCCCCTAGGTGCCAGAGCGGTGGTCGGCCGGGCTCCTGCCCAGTCTCGGCTCCTCCCTC
CTCCCCACCAGAAGGAAAAACTTGGGCCCTTCGAGAACCCTGTGGAATGTTCTTTGTAATCAATGTACATC
CGCTTCCACGGCACGGCCTCGTGCAAAATCGCGGGTTTCGGGGCCTTGGAGCAAATTGCGCTTGTCAGCG
GCGACGTCAGGAGGACAAGGGGAGGGGTTCGCGGCTGAAACTGCAGCTTCGCAGCACAGAGCCATTTTA
GGCTGCTCCCCACCTCGCGGGCCCATGGGAAAGCCGGCCCCGGGAGGGCGCGCCCAAACGCAGGCTGGA
GGAGCCACGGACGCGTCCTGGCCGGCGTGTCGCCATCGTTCAGCCTCGCTGCCCAGGTGGGAGGGGTCA
CCTGCCGCGGGGTCTCCAAGCCAGTGCCGCTTGCTCCCGGCCCCCCCCACTGACAGCACGGCGTCCGAGT
GACCCTGTCTAGCCTCGTTCTGCGCTCCTGCAAACCACGTTGCTGCGCTAACTACAAACCTGGCCAACATG
TCTTTGTAACCCTATCATTTAAAAACGCTTCCAGGCACCTGGCCGCTGCCAGATCAGGTTCGCGGGCCCGA
GGAGGTCCTCCCACCTGCCCCCGCCAGCCCCGGGGACCGTGCGCGGCCTCCGTGTGGCCCCCGCCCACG
AGGTCCCTCGGGCAGGAACCGCCGCGCGACCTCTGTTCAGCGGCCGCGTCCTGGCCACGGGCGACCCCT
GTCGGGAACCCTGTTCCCGGCTAAGTGCGTTCCCGCATTCCGGTGGCTCTCACCCGAGCTCGCGTTT
44; SW vs SM; chr10: 013553837-13554175; 10; C10orf30; INSIDE
TACAGTTGATACCCACCATCCCCATCATCGCTATTAGAATTGGGGTCAATACCCATCATCACTGTTAGACT
TGAGGCCGATACCCGTCATCACTGTTAGACTCGGGGTCGATATCATCATCACTGTTGACTCGGGGTCAATA
CCCTTCATCACTGTTAGACTCGGGGTCGATACCCGTCACCACTGTTAGACTCGGGGTCGATACCCGTCATC
ACTGTTAGACTCGGGGTCGATACCCGTCATCACTGTTAGACTCGGGGTCGATACCCGTCATCACTGTTAGA
CTTGGGGTGATACCCATCATCGCTCTTAGACTCGGGGTTGATACTC
GTCATCG
45; SW vs SM; chr10: 13556159-13556753; 10; C10orf30; INSIDE
CAACATCTGTCATCGCTGTTAGATTTCGGGTCAATATCCATCATCGCTGTTAGACTCGGGGCCGACATCCG
TCATCGCTGTTAGACTCGGGGTCGACACCCATCATCGCCGTTGGACTCGGGGCTGAACCCGTCATCGCTG
TTAGATGCGGGGTCGATATCCATCATCGCTGTTAAATTTGGGGTCGATATCCGTCATGACTGTTAGATTTG
GGGTCGATATTCCTCATGACTGTTAGACTCGGGGCTGATATCTGTCATGACTGTTAGACTCGGGGCCGATA
TCTGTCATCCTGTTAGACTCGGGTCAATACCCGTCATCACTGTTACACTCGGGGCCGATACCCGTCACCGC
TGTTGGACTCGGGTCGATACCCGTCACCGCTGTTGGACTCGGGTTGATACCCGTCACCGCTGTTGGACTC
GGGTCGATACCCGTCACCGCTGTTGGACTCGGGCGATACCCGTCATCGCTGTTGGACTCGGGTCGATACC
CGTCATCGCTGTTGGACTCCGGTCGATATCCGTCATCAGTGTTGGGCTCAGGTCGATACCCGTCATCAGTG
TTGGACTCGGGTCGATACCCATCATCG
47; SW vs SM; chr10: 15294510-15295293; 10; C10orf38; INSIDE
CGACAGCTTCACAGTAGGATTATTGTGATAAAAATGACTCAAGCGATGCAAAAAGTTTCATCTGTTCCCAG
AATCCGAGGGAGAACTGAGGTGATCGTTAGAGCATAGCGACATCACGTGCGGTTTCTAATGTCCCTGGTG
GCGGATACGCCGAGTCCTCGGAAGGACATCTGGACACCACTTTCAGCCACCTCCTTGCAGGGGCGACATC
CGCCAAAGTCATCCTTTATTCCGAGTAATAACTTTAATTCCTTTCTAACATTTACACGGCAAACAGGAATGC
AGTAAACGTCACGTCCGTCCCACGGCTGGGCTGCCGTTCCGTTTCCTCCACGAACGGGTACGCGCTTCCA
TGAGAAAGGATATTTGGCAATTTTATATTCCACAGTCAGGTGGGTCTGCGATAGCTCATTTAATGTTAAAC
GCCATCAGGGGCCTCTCCTCCCGTTTCTGCCAGGGCTTTTCTTGTCTTCTCCTTGGTCATCATCATCATCGT
CTTCCTCTTCCTCGTGGGCAGATCTTCTCTGGTGGGGGCTGGCTGCTGGCTCCGAGGGGGCATCCGCAGT
CCGTCTGGTCGTCTCCTCCTGCAGGCTGGGCAGCTGGCCACCACTTCTCCGACTCGCCCCTCCAACAAGC
ATCGCAGGGCACTGTCCTCGGGGGTACAGACCGTGGTCCCACATTCGCTACCACTCTGTTCCACGTCATCC
AGGTACACGAGCTGCGTGTAGGCCGTGCTGTCTGGGGCTCGAGGCTCTTTCTGCTGGTGCTCTTGGACGG
GCG
64; SW vs SM; chr10: 88112905-88117344; 10; GRID1; INSIDE
CGTGAACGCCCTCGCCTCGCACCTGTGGCGCCTGCCGCGGGGCCCGACCGGAGGCAGTGGCTGTGGACA
AGGGCGGCCCCGGCGTAGGCCAGGATTTCCCCGCAGCCGGACCGGCCCAGCTCCGCTCTTTCCTGGGCGA
ACAGCGCCCACCTCCGGCCCAGGCGGCGGCGCCTCCGCCCGCGGCGCGGACAGCGAGAGAGAAACCGGC
TCCTCCAAACCTGGTGGAGGAGCGCTGCAGAGAAGCGCCGGGCTGAGGCTCTGGGGGCCGCGGGGCGCG
AAACGCCGCGCCTACAGGTTATGCCCGGGAGAAGGAGACAGGTCGGGCTCCAGCCGCTGGGCGCTCCTC
ACCTCGAAGCGAGGAAAACACCGGGCCACTGAGATCAGGGGAGGTGCGCCCGATACAGGTACCCGGCAC
GCAGACACGCCCACCCCCAAACACCGAGAAACAAAGACTGCCCGAGCCACGCACGCCTGCGCGGCCAGC
GCTGGGCGCACACCCGCGCCCACACAGCCCGAAGGGCGCCACGCAACCCGCAAGAACACCAGCTCCCCG
CGCTCGCAGGCTCTCCGTGCCGGCCCGCAGCGCAGAGCAGTCCCGGCGCCGCTGCCTAGGTGGGCCGGG
AAGGCGCGCCACCGCGCATGGCACCGCGGCTGCCGAGGAACAGAGGGTGCCCTGCGCAGCCCAGCTCGT
CCCAACCCCTCCGGTGCCCACTGCTGCGACGCCTCGCAGGCCGTGTCCCAGTGGGCCCTGGGCACAGCGG
TCACTCACCTTCCTGCACAGCCTGGATGGGTTGTTGGCCTCGATGACCTTGATGGAGTAGGTGATCTTCTC
GCTCTGCAGGATGTCATCGTTGAGGCTCAGGTCGGATACCGCCAACTGGAACACCCTGTCGTCCTTGGCC
GCGTTCTCCTCGAAGATGGCACCTGGAGGAGAGAAGGGATCAAGACCGGACTGGACAAGAACCCTCTCCC
CGCTTCCCTTGGCCCGAGGGTCAAGGCACTCGCAGACCGATGATTGCCGGGTGGTGGGAAGTCTGAACTG
GGATTTCAGCTTGGCGGGGTAGATTAAGGCTCTCCGATCTCCACCTGCACAGGAATATGTTCCCCTCCCCC
CACCGCCCTCAGCGCACACGTGCACACAGTTGACATGAGTTACACATGCACATCCCACAGGCTGCCACCA
GGTCACACACGTGTCTCACAACCAAGGCACCACATGTCCTAGCCATGCTCCACACAAGGGACTAAGCCAA
GCTGGGGTGGCCCCAGGCAGCGCCCAAATCCTTGACATGGTTCCATAAATCCCATCCCAGGAGCCAGGAAG
71; SW vs SM; chr10: 102986025-102986636; 10; LBX1; PROMOTER
CGGGGGGCGCCGGGCGCAGGCCGGGCATGGGGCCTGAGCTTAGGCCAGGTGGAAAGGTGGAAGGACCTA
GTGGGGACAGACGAAGAGACCGAGGAGCCGCCCGCCCGGCTAAATGGACACAGGAAAGCCTGAGTCAGG
CTTCTCATAATAAATAAACTGCACGTGAATAATTCAGCAGTCGCGCGGGGGCCGGTTGCATCAGCGCCGC
CGCCGCCGCGCGGCGCCCAATTCCCCGCGGAGGGGAGTAGCCAATTAAGGCACTTGAAAAGGGAGTCGG
GTGGAAGATCCCCCGCCACCAGTATCCTGGATTTACCCAGGTCGAGTTCAGAGAGCCTCCCCGGTCCCAA
CCCCCTCGGGCCCCATGGGTCAGGGGGCCGCCTGCTGGGAAGTGCTACCTCAGCTAAGCCGCTCAGGTGT
CCCGAGACTCCGGGCAAGGGAAGACAGGCGGCGAGACGGACCAGAATAAGGGATGCGGACGTCTGACCT
GTGGAAAACCCAGCATCTGCAGTGCCCAGCCGCACAGGGAACGTGGGCGGCGTGGTTCCAAGCACAGTG
AAGACGCCAGGCTCGGATCTGTGCTCAGAGCCGGGATCCCTCCGGGCTGCTTCG
108; SW vs SM; chr14: 28317076-28317375; 14; FOXG1B; DOWNSTREAM
CGTAGCGACGACGTGGTCCTTGTAGGACCAAGCATTCTTGGCATTCTGTCGAGATTGAGATTCCAGAGCAT
CGGATGAACGGGACTTATAGCTAAGGCGTACTCACCCACCCCTCCCTTCGTCTTTTACGCACGCAGCAACT
CGTCCTCACGTGCATAGGGGTAGTGGACAGTGTTGACTTGAATTGCTGTCCCTCGTTCCAAGCCTTTCCTG
TGAATGAACCCGAAAACACTCGACAGGTCGTGAATAATCGTTTTAATGAGTGTGCAAAGCGTGCGACGGG
GTGCACCGACTGTCG
126; SW vs SM; chr15: 58079172-58079459; 15; FOXB1; PROMOTER
CGCTGGCGGGGGTAGGGGGTGTGGGTGGGTACGGAGTCCTTTCACTGCCCGTCGGCAGTTGGCACCAGA
GCGGAAAGTGTGTCCCCTCCCCCGCCTCTCTCCCTTGGGCAGTTTGATTTCCCGCCAGCTCAGTCGGAGTG
GCCTGGAAGAGCGGGCTCAAACTCCAAAGGCAGTCGTGGGAGAGTCGTAGCGGATACGTTTCCCCTGACA
TGCGCCGGGTGCTCGTCTCTGCCCCCCACCCGCCCCCAAAACCCAAACCTGCAAGTCGATGTTGTCCGGT
GACCCCG
127; SW vs SM; chr15: 58083339-58085812; 15; FOXB1; PROMOTER
GTGCCTAAAGTTACCTAACGATACAAACCGGATACAACGCAGAGGAAACAGAATACCCCAGCCAAGCAAT
TTCCATGTCAAACATCATCCGCGCGGCTGCTCCATCTGTGAACGTGAGTGGTCGCCTGCTCCCTCTTCCGC
GGCGGCCGCTTCCTCATACCTTCACACGGCGCACACCGGCCGGCGCGTCCAGCTGCCTGCCCAGTGGCCG
AGGCTCTTCCCCCTCGCCCAGTCTTGAGCTGGAAGTGATTCCTATTGGCCAAGGTGTCCATGTAAATAGGT
GTGAAAGAAACAGAGCTGGCCGGGCTCTCCCTTCTCGCTCAGTCCCCTCCCTCTGCAGCCCCCGCTCCCC
CTCCTCTTCCTCCTCCTCCCAAGGCGATTGTCATATGATAGCTAAGAAGTGGCACATTAATGAAGCGCCGC
TACAGGGGTCTTTTCTGCTCCTGTCACCGCTTAAACTATCAGATGGTTCGAGGGAGGACATGGAGGCAGC
CACCTAGCTCAGCGGAGACGCGGAGCCCACAGCAGCGCCCTCCGGAGCCCTAACACGTCGCTGCCACCAT
CCGCGCCGGGACTCCGCAGCCGAGCTCGGCCGCCCGCAGGACGCTCCAGGAGCGTCGCGACCGGGCGGC
ACGGGACGCTGCGGGGCTGAGCTCAAGAGCCCAGGTTCGCGCCGAGTCCAACCGGACCCGGACGCTGCG
CGCGGAGTGCGCGTCGAGTGCGCGCCGAGAGAGAAGCGGCGCGCAGCGGCGTCCTCCCGGATGCGGACG
CGCAACTTGAAGCAACTTAAGGTGAGCAGCTCTCTGTTCCGTCCCTGCCCCCTATTCTGGCCCCAGTACCG
ACTTACTTCCCGGCTATCCTCGCGCCGTTCGCCGGCTTCCCCTCCCGCGCCCACTAAGCCCGCAAAGTTGC
TGGCGAAAGAGTCCGGGCGCTGGCTGATCGAGCGCCGCAGCCCCACCCCCGACCCCCGAAGTCTGTTACT
CGGTCTGGCTGACCCCGCCGGTGTCTCTGTGCATCCATGCTACCTTTCCCTATTACCCACCCCCTTCCCAG
ATCCGAGCAGTCCGCCGGCCCGCGCGGACCCAGAGCAAGAAGAGGGCGAGGAAGAAGATGCCTCGCCCG
GCCGCAACACGTACAGCGACCAGAAGCCGCCCTACTCGTACATCTCGCTGACCGCTATGGCCATCCAGAG
CTCTCCCGAGAAGATGCTGCCGCTGAGCGAGATCTACAAGTTCATCATGGACCGCTTCCCCTACTACAGG
GAGAACACGCAGCGCTGGCAAACAGTCTGCGCCACAACCTCTCCTTCAACGACTGCTTCATC
167; SW vs SM; chr17: 47590175-47591465; 17; CA10; INSIDE
CGACGGGAAAACGGGGGGAAGGGGGGAGCCCGACACGGCACACACACATACACACTCGCACACACTTCC
GAGCGAGTGCACACTCGCACTCCCACCCGACAGCCGGCCAGGGACAGTCACCCCCAAGTCAATATCGCAG
TTTGAATTGTTCCGGCAAATCTCCCCTCGGGCTCGACGGATGTGCGCCCCAGATGTGCTGACACATGTCCG
ATGCCTCGCTGCCTTGGAGGTCTCCCCGCTCGCGTGTCTCTTCTCTTCGCACCAGCGGCGGAAACCGCACT
AGCAGCGGCGGGGCGGCGGCGGCGGCAGCAGCCACCTGAAGCCACCAACACTGGGCTCTTCCAGCAAAA
ACGAGACCCCGATTCGTCTGGCGCCCCAAGAAGACATAGACGATAGCCCCCCGCCGGGCTGCGCCGTGCA
ATTCCGGGCTCCCGGGAGCGCGTAGCTCGCTGGCTAACCCAGGCAGTCCGCGGCAAGTTGCCCTCGAAGT
CCGCCCCCCTCACCGGGGCATGGTCGGAGGGTGGCTGCTGCGCTCCGGGGCAGTTCTTCTCCTGCTTCCG
GGGGGCGGGGAAGGAGCAGACACAGCAGACACACAGAGAAAGAGAGGCAGGGATTATTGCCCAAACCGC
CAGCCGCCGGCAGCCTCCGCCGACCCTCCCTGCTCCCCAGGTCCGCGCGCAGCCTGCAGCCTCTCAGCCG
GGTTCCGGCAGTGCGTCCAGGGCGCCGAGGGGAAGGGCTGGGCCCCGGGGACTGGGGCGCGGTGGGGG
CACACAGACTCTCCAGGTCGGCGCGCCCTTCCTGCTCCTCTGCTATTTTCCTGAACTCCCCAGAACCCCCA
GTTGCCTGGCTTCCATCGCCCGCAACTAGCGCCGCTGTCGAGATTTTCCGCAATACAACTGCAGGGGTCG
TTATTTCCTCGCCTACGGATCCCTACGCTTCCCAACTCAGAGAGAGGAGGACAGGTGGGGGCGGGAGGGG
GAGGAGGAGAAGGAGGCTTGGCCAGGTGAGCGTCCTCGCCGCCGCCGGGCGTCCCAGCGTCAGCTCCGC
AGCCCGGCACCCGGGGGCGGAGGCAGGAGGCCCGGGCGGGGAGGTGAGGCTGAGCGCGGCCATGAGGA
GGGGAGGAGGAGGCTGGGTGTCACAGCTTCAGGCCACCTTGGCCGCCGCCTCGGCCCCAGTCCCTGGCA
GCCGCCTCCGCACTCCGCCCCGCCCTGGCTGCCTCTGTTACCCTCCAGGATTTTCGAGTTTCTCTTCTTAA
AAAGAACTTCGTGCTGCGGGTTCGGCGG
174; SW vs SM; chr17: 67623575-67623903; 17; SOX9; PROMOTER
CGTGGGTCCGCCTACCCCAAGCACTTTTTGTGACGTCACAGCTCCGAGGACCATCCGGGGGCTTTACTCTC
GCGGAAGCCCAAAAGTTGGGGTTTGACCTCATGACCTTGGCCTTCCCGGGGGGCGGAGGCCCTCGGGACA
GGACGCGCTGTCCCCGGAGTCCGGAGCTCAGGCCAGTGGCAGTCGACCCAGCCCCCGAGACTCCCTCACG
CCGCTCCAAAACCAAAACGGAGCCCAACACGAAGCTGGGTGAAGCCGTAGCTTGCAGGAGCCAGGGAGAT
GCGCTCTGCCCGGACTTCCCGGGTCCTGTTGAGACGGAAAGGATCG
175; SW vs SM; chr17: 67627870-67631593; 17; SOX9; INSIDE
CGACTCGGCTGACGTTTTTGACCCGGCCAGGAGGCAAAGACCAAAACGTCAGAGCAGTAGCCCTGTTACT
GAGGAGCGTCGGCAGGGTCGCGGGTAGAGGGGGCTGGAGAATGACTTGTCAGAGCTCAGGTCGATGTGG
CGCGGGGCGGCCTCGAGAGCGCCGGGCTCCTGCGTGGCCACGGCCGCCGCTGCCAACCTTCGCGGGGAC
TTAGCTTTGCTTTCCATTGACTCCCTTTGCAAAAGCGCAGCAGAATCCTGACCAGCCGCACCAGCCCCGGC
GAACCCGAGCATGTAATCTATTTATATGGATTATTACGGAGGAACAGCGGGCGTTGAGTCACCAAAACATT
TGCTTCAAAAGACTATTTCTAAGCACTTTTGCAGGCAGGCAGGCTCGCTCCAGGCGCGTAAACTCGGCTAC
GCATTAAGAAGCGGCTGCTTTTCGAATACTGCAAACCCAGCTAAGTCCCCGGTGCCGCGGAGAGAGCAGT
GAAAAGAAATGTCGGAGGTGGGGGTAGATCCTAGTCTAGACACACACACTTGCGCGCACACACACACACA
CACACACAAGATTCGCGCGGAGAAGGCACTAAAATTCTGGCATTCCGAGAGTACGACAAACTACACACTT
GGAAGTCCCGGGTCCCCCGCCTTCCCCGCAGCACCCCCCGCCCCCCCACCCTACCGTCCGCCCTTTGGCT
GCGATCCCCTCCCCTCTCCTCCCCTCCCGCCTCGTCACCCAGCCCAGTGCCACAATCCTCCTCCCTCCCCA
AAATCGGGTCCAATCGCTGCCTGCCAACCCTGGGACTGCTGTGCTGTGATTGGCGGGTGGCTCTAAGGTG
AGGCGGAGTATTTATTAAAGAGACCCTGGGCTGGGAGTTGGAGAGCCGAAAGCGGAGCTCGAAACTGACT
GGAAACTTCAGTGGCGCGGAGACTCGCCAGTTTCAACCCCGAAACTTTTCTTTGCAGGAGGAGAAGAGAA
GGGGTGCAAGCGCCCCCACTTTTGCTCTTTTTCCTCCCCTCCTCCTCCTCTCCAATTCGCCTCCCCCCACTT
GGAGCGGGCAGCTGTGAACTGGCCACCCCGCGCCTTCCTAAGTGCTCGCCGCGGTAGCCGGCCACGCGC
CAGCTTCCCCGGGAGCCGCTTGCTCCGCATCCGGGCAGCCGAGGGGAGAGGAGCCCGCGCCTCGAGTCC
CCGAGCCGCCGCGGCTTCTCGCCTTTCCCGGCCACCAGCCCCCTGCCCCGGGCCCGCGTATGAATCTCCT
GGACCCCTTCATGAAGATGACGACGAGCAGGAGAAGGGCCTGTCCGGCGCCCCCAGCCCCAC
199; SW vs SM; chr19: 42586101-42586705; 19; ZNF569; DOWNSTREAM
CGATTGGGGCCTCAGCCTTAGTTCTTCCAGCTGGACCCTGGGATGGTGCGGGGCTGTGGCTCTGGGAAGT
ATCTTGGCCTGCACGCGGTTTACATCATTGGGAGCACAGGCCTCGCCCTCCGAACTAGAGGCCCAGAGCC
CTTCGCGCCGAGCGTTTCCCGCCTTTCCCCTGTCTCAAGTCATTGCCCAGAGGCCACTGCGGGCCGTTCCT
GCCTGTCCGTGGAGCTGCGGCCCCCGTGTTCCCAGGGTGAACGAGCACGTGCGAGGCGGTGGTGCTTGTA
TCCGGGATAACAGGTAGGGCGGCTGCATGCTTCATAGAGGCCAGCCTGTGCCGACCGGGAGCTGTAGGAC
GGTCTGTGTCTGGGGCTGCTTATGGGTATTCGCGTGCGTCTGCCGGTGCGCGGTCCGAGCCTACTCACGA
GAGCGTGTGTGTGTCTTCTGTCTCGTGTTGCTATGAGTTTGCATCTGTGTGGCTGGAATAGCTTGTTTGTG
GGGGCCCGCGCGTGACCTGTGTGTGCGTTACTGTGTGTGTCTCAGGCAGGATAGTGACGGGCCGTGTGAC
TGTGACGCCATCATCAGGTTGGTGAGATGGCGTGACCGCG
204; SW vs SM; chr19: 57082579-57083180; 19; ZNF577; INSIDE
CAGCAGACCCCTTTTTAAGTACGCATGTGATAAGCAATGAACACGAACTGCCCAGAGCAGTCTCCAACACT
GACACGATTCGCTTCCCCACCACGACGCCCTAGCGCTACTGTGCAACGAAGACCTCCAAGCACTGGTTCC
AATGCGGAGACCATGGGCTCCCAGACTCTGGGAACTCCAACACGACTGCGAAACGAACTCCGAGCGAGGA
CTCCCCGAGAGCTCCCCGCAACACGGACCTCACGCGCTAGCGAACAACAGAAAAAAAAAAGCGCGCTCTC
CCTGCCCCTGAACATTCCCAGAAGCCCACGCAGACCAGACCGATGACCTGTCTCCACTGCTGGAGGCGAG
TCAGGGACCCGAAGTCTCTAAACACTCGCCTCTACCCGCCGCCCCGCGAACCCCACACACTGCAGACGCG
ACACTCGCAAGTTTCGGGGATGGCGGCCGGCGAGGGCATACTGCGTCTTTCCGGAGACACGGAATACGGC
ACCAGCCGTCCCTTTATGATGCAATATGTCTGCGCCCAGGGGACGCTTGCTGGGAGCAGCCATTTTCAACC
CTACTGCCGTAGAGCAGGCGGAGTCCCTCTTTTCGCG
233; SW vs SM; chr2: 119329502-119332035; 2; EN1; PROMOTER
CGAGGAGGCTGCAGGGACGCGCATGGAAGAGCCGGTGCGTGGGAGGGTTTGCGGGGGGGACATCGCGCC
CCCTAGGGGTGACCCCAGTGGGTCCCGTGTGCTCTCCGCGGAGCCGGCGGAGCCTTGTCTCTGCACCCGG
CGCGCAGCGGCCCCTTAAACAGTGGAACCGTGAGGCCGCTCTAAGCCGAAGGGCTGGAATCTGGGTTTCT
CGGGTTTTATTTTAGACCATTCGGCACCAAGCCCGAGCTCCCCCGCCGCACCGCTTCCAGTCCCCTTTCTT
TCCATAGAGCGACCGAAGCCGGCGGTGGCGCAGGGAGCCGAGTCTGATGAGCTCGCGGGCGGCTGAAGG
CCGGCTTCCCTGTGGGGAACGCGCCACCTGTCGGCGCCAGTGAGAACTGCGTCTGTGTGGCGCCCTCGGG
GTATTCGGGGCTGCGGGGAGATGTGTGCCTGAAGCCCTCGCTTGCGGTGGGGACGTCCGGCCTCTTTCCT
GGCAATTGACCCCTGAGGCGGGAGAGACAACGGAATTCCCACAAAGGGATCCTTCTCGGGATCTCCCCAC
CTCAAGACAGCTAAAGCTGGAGGAAAAGCCCCTCCGGGGGGTGGGGGGTGCGGGTTTGCCCTGGATTCC
GAAAGCAGAAAATACCCGAGCCACACAGGGACGGGCGCCGCGTTGGTAGTCGGGGCTACGTTCCTACTCC
CTCTACCTCCCCCGCGCTGTGTGACCCTGGGCGGAACCCCGCTGCTCTCTGGGCCTCAGTGTTCTTATTCG
TAAACTGAGGGCGTTGGAGAGATTGGTCCTCTCCCAACTCTGACCTTGAAACTGATACTGAATCTGAGCAG
CGTCTGTAGACACCTGTGCCTTGCCTTCTATTTCTAGCCTTGAATAAATCCTGGACTTTTATGTGCCATTTA
TATCCTAATCTCATATATATTTAATGTATAACTGCTGCCATATTGTTTTCTCAATTGTCTAGGTTTTCATTTG
GATGGGGTTAGGATGGTCCAAATTATCCCGATAAGTGCCCATTAACTTAAACCTTTTTAAAAAATGAAACC
AGTAAAACTTCATTCACTTTGCAGTGTGGACACTGCTGGAGAGCACCCATGTCGTGGGTCCGCGAGGACA
CAAGGAGGGGCTTAGAGACATGCGGGAGGCTTAGATGAGAAGACAGCACCCGGGCAGCGGTCAGTGTTA
GAGAGAGGACCCGTAAGAAGGGCCGAGGCTAGAGGGAGAGCGAAGACTGAGCCAACGACGCACCTGAGC
CCTGGGGTGGGGGTGGAGCGTGGCTCCTAACCCAAATCTCCCTGCCAGGCAGTGTCCGAC
264; SW vs SM; chr20: 54633629-54640196; 20; TFAP2C; PROMOTER
ACCATGAGCTTCCAGTTCCTACGGGTGAGAAAAGAGGTGTCTGTGTGGAGGGCAGGTGCGACCCCGGGG
GCTAGCAGAGAGGAGAGGCTGCGGGAGGACTCGCTGCGAAGGGCGAGGGGTGGCGCTGGTGGGACGGG
CGCCTGGGGCCGTGCAGGGTGGCTCCTGGGTGCTGCCCGGGCTGCCTGTCGCCCAGTACTGGCGCAGGA
AGACGGGTCCGCGCAGCGTCTGGCAACAGTGGCCTGCTCCACGCCTGGAGGCGACCAAGTTCTGAGTTAA
AGGCGCCGGGCTTAGCGGGAAGTGTATGGCGACCCAGAACACGGAGCGGAGAAGGCCTCAGGGGACACG
AGGCTACCGCCTTAGTCCTCGGGCCTGCGCTCCGAGCGGTTAGGGTGCGTACGGATGGGCTCCGGGATGT
TAGTGGAGAGGTGACAGGAGTCTACCATCCCACGGCCAAGCGGTGAGGCCTCCGGCGGGCGGGGGTCCC
CCCCGGGGCAGGGCAGGGGGAGAGTCAGGCATGTCTCTAACGGGCTCCCTAGTAGAACCGCTAGGAAAG
TGGCCTTCAACCCTAGGCACCTTTGTGGCTTTCAGGTAGTTGGGCGACTAAAAATTCACTTTTGCCTGCGT
GAAATGGGACAGGTGGTTGTCAGGTTAGAGACTGTGCCCACGAAGTCTCGTTTGGCGGGCCGGGACTGAC
GTGGACCCGGGCCCTCCTCGGAAGCTTGGGAACCTGTGAGCCCCTCAGCTCCTCGCCTCACTTTGCCTGT
TTGAAAAAAGGAGTTGTTTGAGAGAAGAGTTAAGGCTCAAAAGGTTCTAAACGAAGAGCATGCGGCCTGA
CGCGGAGCGCAAAGAAGCGAGCAGTGAACTGAATCTGGTGGGACTGAGACCAGAGGCGTCTGTATGCGG
CGGCCGCTTCGCGCCCTATTAAAGCAATCTGTTATTTACGATAATCATTTTGTAATTATTTTGGAGTGGCTG
TGACTTGATGTCTGTGGTGCCCCAGGGCATGCCCTTACTGGACATAGATACTTCAGGGTGCCCTTTGACGC
CAGTGTCGGTCCAGTGGGTGCCAGTGCCGCGAAGGGAGGGTGGCGGGCGTGAATGCCCCCTCCTCCTGG
GTTGCCGCAGGCCCCGGCCTTTCCACCTTGCTTGATCCTGGCGGGTCTGCCACTTACTGAGGTCCCTACCG
GCGCTCACGTTGTCCCGAGAGGCGGGACAAACGTCCGGCGCGTGGCGCGGAGTCTGCGAAAGCGCTCGG
GGGCCTCCATCTTCTGCTCGGGAGTCCCTCCCTGGGGCGGGAAGAGGAGTCGCAGATCTGCCCGAATCT
280; SW vs SM; chr3: 148619483-148620015; 3; ZIC1; DOWNSTREAM
GAGTGCGTAAAGGGAAATTTTTGCATTGGTGGATTTATTGAAAGCATGGAAACAGTCTTCGGGGGTAGGT
GTAGGGGGTGCAACAGCGAGACTTCCCCACAACACCTCCACCGAAGGCTGGGTCGTCGCGTTTGAGGGAC
CCTCCCGCCACCCCGCAGCCTGGCGGGGCGCTTTCCAAATCGTCGCGGCAGGCTCTGGCCGGGCAGGGC
GAGATGTGCGCATGCGCGGCCTGTGGCCCGAGGTTCCACGTGCTGATGAATATGCATGAGACTCCCCCGC
CCTCGCGGGCTAGGAGAGAACCAAGCAGAGGCTCCGGCCTGTGAAAGTCGCTGGCTAGGCTCCCAAAATA
GTGCGGCGGGGTAGCTGCACGTGTTTGTTTTCAAACCGCGCTGGTTTAAGTGAGTTCACACTGCGGAGCC
GACAGCAGAGGGTAGAGCAACCTGGGGCTGCTGCCATTGAACGGCGAGTTGAGCGGGCCTGTCAGGGCC
TCTCCGCCGAGGGCCGGGGGCTGCATGGTGCTCGAGCCCCAG
289; SW vs SM; chr4: 134288613-134289892; 4; PCDH10; PROMOTER
CGCGTTGCCCCTGCGCCTCCGGAAGGGGCACTCACAGCTGGTCAAGCGCGTCCTTCGGAACTCGGGGAGG
CTCCGTTGGGGCTTACACAGAGCTAAGCCCTGGGCCAGGGAGGATGGATGCAAGTACGTGCATGTGCAAA
CGTGTTCGCAGATACCCGCAGCGGTGCACACTCGGGCCCCTCGTGTGCACGGGCCCTGCCCACCACCCCG
CCCGCGTTCGCCGCCGCCCCACTGTCCTCATCCCGCGGGCTGACCCCAGGATTGGCAGAAATCAGTGGTC
TAATCTAGCATGTGGGTAAAGGGATCGATCTCCAATTGCCAAAAAAAAAATAGAAAATAGCCGGTGTTCCC
AGCCGCTGCGTGGCACTTGGCCGCACAAGGCGCAGGGATATCAGAGGCGCTTTGCAGCGCTTGGCGGTG
CTGTGTGCCGGATGCCCCAGAGCCCGGCGTTAGGATGCGGGCTTGTAGGAAGCGGCTCAAATCAACTCCT
CAGTCACTGATGAACGCGCTCACGGCTCGAAGCTAGGTCCTCGAGTGAGTTAATCTACTTGGTAAGTATTT
TGTGAATATGTATTTTGGGAGGAAAGAAGCACGTCGAACGCGTCTGCCCGTCTGTAAGCGCGTCATCCCC
ACATCCTTTAGCGTGAATTCCTCCGCTTTTTAGGAGTCACCTCCACCCCCTACTCCGTATGCTTCGCGCCTT
TCCTCACGGCCCCGTCAGACCCCCTCACCTTTAGATTGACACATGCCATATAATACTCACTTTTAAAATGC
CCTGCCAGTCTCTCTAGGGTCCCTTAATTAGGTAACCCTTGCCAATTAGTGGGCCCTGCGCTACTTTTTCC
CTTCTCGATGATTTATTTCCATGATGCGTATTAGGGAAAATACCTTAAAGGAAAAAGAATGTTAGCATCAT
TGGAAATCCCGCTCCTAGGAGAGGATATCGCAGCTGTGCTATTATGTTTTCGCATTTGCTGATGCAAACAG
GGGAACCTCTCTATTCCCTCCCCATTACCTGCGGCTGGGGACTGGGAACTTTCCGCGGCATTGTCCCCAGC
CAGCGCCTCGGGACCTGCGGGGCTGTTCTCGCTCTCACACTCACACTCACCCCGGCCGCCGGGCGAGAGT
TCTGTCCCGCCCCGCCCGGCTGCCGCGTGACGTGTCTGTTTGGCGGCCAGTTTGGCCAATCATCGGCAGC
TCGGTGGGTGGTGCTCCTGGGCGATTGGTTGGCAGAATGAGGGCGCTGCGCAAAAACGGAGAAGCCGAG
CGCTCG
290; SW vs SM; chr4: 134291113-134293078; 4; PCDH10; INSIDE
CGGAGCCAGACCTGACGGTGGAAATCTCTGAGAGCGCCACGCCAGGCACTCGCTTCCCCTTGGAGAGCGC
ATTCGACCCAGACGTGGGCACCAACTCCTTGCGCGACTACGAGATCACCCCCAACAGTACTTCTCCCTGGA
CGTGCAGACCCAGGGGGATGGCAACCGATTCGCTGAGCTGGTGCTGGAGAAGCCACTGGACCGAGAGCA
GCAAGCGGTGCACCGCTACGTGCTGACCGCGGTGGACGGAGGAGGTGGGGGAGGAGTAGGAGAAGGAG
GGGGAGGTGGCGGGGAGCAGGCCTGCCCCCCCAGCAGCAGCGCACCGGCACGGCCCTACTCACCATCCG
AGTGCTGGACTCCAATGACAATGTGCCCGCTTTCGACCAACCCGTCTACACTGTGTCCCTACCAGAGAACT
CTCCCCCAGGCACTCTCGTGATCCAGCTCAACGCCACCGCCCGGACGAGGGCCAGAACGGTGAGGTCGTG
TACTCCTTCAGCAGCCACATTTCGCCCCGGGCGCGGGAGCTTTTCGGACTCTCGCCGCGCACTGGCAGAC
TGGAGGTAAGCGGCGAGTTGGACTATGAAGAGAGCCCAGTGTACCAAGTGTACGTGCAAGCCAAGACCTG
GGCCCCAACGCCGTGCCTGCGCACTGCAAGGTGCTAGTGCGAGTACTGGATGCTAATGACAACGCGCCAG
AGATCAGCTTCAGCACCGTGAAGGAAGCGGTGAGTGAGGGCGCGGCGCCCGGCACTGTGGTGGCCCTTTT
CAGCGTGACTGACCGCGACCAGAGGAGAATGGGCAGGTGCAGTGCGAGCTACTGGGAGACGTGCCTTTC
CGCCTCAAGTCTTCCTTTAAGAATTACTACACCATCGTTACCGAAGCCCCCCTGGACCGAGAGGCGGGGG
ACTCCTACACCCTGACTGTAGTGGCTCGGGACCGGGGCGAGCCTGGCTCTCCACCAGTAAGTCGATCCAG
GTACAAGTGTCGGATGTGAACGACAACGCGCCGCGTTTCAGCCAGCCGGTCTACGACGTGTATGTGACTG
AAAACAACGTGCCTGGCGCCTACATCTACGCGGTGAGCGCCACCGACCGGGATGAGGGCGCCAACGCCCA
CTTGCCTACTCTATCCTCGAGTGCCAGATCCAGGGCATGAGCGTCTTCACCTACGTTTCTATCAACTCTGA
GAACGGCTACTTGTACGCCCTGCGCTCCTTCGACTATGAGCAGCTGAAGGACTTCAGTTTTCAGGTGGAA
GCCCGGGACGCTGGCAGCCCCCAGCGCTGGCTGGTAACGCCACTGTCAACATCCTCATAGTGGATC
309; SW vs SM; chr5: 133887842-133891327; 5; PHF15; PROMOTER
CGAGAGAAGGTGAGCTCGGCGGGCGCAGCGGGTTGGGTGGGTGTGGCCCGCGGCTCCGGGAACAGACCC
AAGGCCCCGCCACCGCCGGCTAGCAGCCCGACAGCCCGCCCGCCTGGCGAGCGCAGGCCTTCTTCCAGAA
ACTGCGAGGATCCGAGCGTACTGTTTGTGCACCACAAGGTCAAGTCGGGAAGTGGAGCCGGAGGAGGAG
GGGCGAGGAGGCGAAGGGTGGGGAGAGGGGCGCCCCGCTTCCTCGCCATGTGCCAGCCTTTGGAAGTTA
CCCCTCGGTTTTTAACTTTCGGGGTAATGGGAAGGAAGAGCAAGGAGGAAGGGGTCGCCCCGGGGCAAAA
TCCTGCTGGGGCCAGGATGTGCAACCACCCACCCACCCGCTCATCACTGCCTTCTCCACCCCCCGGAAAT
GCGGGGCAGCGCTAGGCGCCAGGAGGCACCCGGGAGGGGGAGGGGGCGACGAGCCCAATGGGGACCCT
CTCTACGGACCGCCCCTCTTTTCTTGAGGTCGCCTACAATTTCAAGTTCCCCCGCCCGGAATGTTAGTTTT
CCATTTGGAGTGGGTGCGGGGAGGAGGGCCGCGCCCCCTCCCCAAGACTCGCGTTCGCCCCTCCACCCCC
TCCTGCCAGCACTTTCTGCTCACTTCTGGTGCTGCAAAACGCCACGCAATTTATTCGATTCGCATTTTAAAA
CCAGCGATTCAGAAGCAGGGCCTAGGGCGAGGGTCTTCCAGCGCTGGAGCCCCGGGGGGCGGGGTGCTC
AGTGCAAACCTCGTTCCCTCGCGAGTGTCGCCTCCAGGCTGTTATTTGCAAAGAAACGTCTTTTTGACGCA
GGGAGAAATGGCAAATTTTAAGTACGTCATTAATATGGCGCCAAAAGATTTTTTTAAGTATAAGCTCGCTT
TTTTTTTTTTTTAAGGTTGCGGGGGGCGCCGCCCGGGTCTGGGCGCGTAGGGGGCGGGGTGTGAGCAGAA
AGTGTGAGTGAAAGAGTGGAGGGGCGGGGTATGTGTGTGAGTGTGTGAAGTGTGAGCAGACCTGATGGG
ACTTGCACGGGCGCAGCCGCCGCTCGGGCCCGGCCCTGGGGACAGGGCGGGCTAGGGGCGCCCCAGAGT
CATGGGGAGTCCGGGCCCAGGGTGCCAGCAGGCGTGGTGGTGGGGCTGCGAGGGAGGGCACCCTTCCCC
CACGGGGCCCGCAACGCTACCTGGACTCCCCGCCGGAGCCAAACAACTGGGCGGGGGGTTGGGGGGGCG
GCGACGGGGGTGTCGGGAGCGGAGATCGAGTGAATAAGAAAAAAGTGGCTACTCCCCCTCCCTCGCTCC
328; SW vs SM; chr6: 5080084-5080849; 6; LYRM4; INSIDE
ATCCCTATTCCTTCTCCTTCCTCTCCCTTGGTAACGGCACTCCTAGGGCTGTGGAGGGTGCGGTTCACTCC
TGGGACTGTGGAGGGTGCGGATCACTCCCGGGACTGTGGAGGGTGCGGATCGCTCCGGGGCTGTGGAGG
GTGCGGATCGCTCCCGGGGCTGTGGAGGGTGCGGATCGCTCCCGGGGCTGTGGAGGGTGCGGATCGCTC
CCGGGACTGTGGAGGGTGCGGTTCACTCCCGGGACTGTGGAGGGTGCGGATCGCTCCCGGGACTGTGGA
GGGTGCGGATCGCTCCGGGGCTGTGGAGGGTGCGGTTCTCTCCCGGGGCTGTGGAGGGTGCGGTTCACT
CCCGGGGCTGTGGAGGGTGCGGTTCACTCCCGGGGCTGTGGAGGGTGCGGTTCACTCCCGGGACTGTGG
AGGGTGCGGATCGCTCCTGGGGCTGTGGAGGGTGCGGTTCATCCCGGGACTGTGGAGGGTGCGGATCGC
TCCCGGGACTGTGGAGGGTGCGGATCGCTCCCGGGGCTGTGGAGGGTGCGGTTCTCTCCCGGGGCTGTG
GAGGGTGCGGTTCACTCCCGGGGCTGTGGAGGGTGCGGTTCACTCCCGGGACTGTGGAGGGTGCGGATG
CTCCTGGGGCTGTGGAGGGTGCGGTTCACTCCCGGGACTGTGGAGGGTGCGGATCGCTCCTGGGGCTGT
GGAGGGTGCGGATCGCTCCAGGTGTGATTTTCATGGGAATGGAACTGGCTCCCTAGGTGGTGTTCATTTC
379; SW vs SM; chr8: 65653638-65653908; 8; BHLHB5; PROMOTER
CGAACGCCGGGGGAGGGACGGTGGGAGGGGTGCGGTGAGCGAGGGGCTGCCCTGCATGTAAACAGCCTC
GGGGTCCCAGACGAGACAAGTGGGACCGCTCAAGCCTGCAGAACCCCCGGTCTCGGTCCAGGCACAAGA
GCCTCCCGTAGCCCCGCCTGATCTTTCTCAGTCTTTAGGTTCCAGGACATCCAAAGGAGCGTAGGTAACCG
ACGTCTACGTAGTATTTCTGTCCCCGGAAGACTGGATCTCAGGGAATTATTATGGAAGATA
386; SW vs SM; chr8: 72916429-72917309; 8; MSC; INSIDE
CGGGGCAAGGGCGCGTTCCCTATCGCAGGATCACTTGCTATGGTAAGCCGCCCACCCTGCGCGCTCCTCC
GCGCGGGGAAGAACCTGCGCGGCAGGACGTGGTGTTGGAGTTGGGGCGCCCGGAGCGGGAGTGGGGAG
ACCTGATGCAGAGAGTCTGGAGTCGGAGCTGGGGGTGCTGCAGGTAGGAGCAGGAGCGGGGCGGAGAGG
GAGGCCCGAAGAAGACCCCACACAGGTTGGCGCAGCGGGGCTTGGGGAGGCTTCAGCCCAGAAGTGGAG
AGGGTTGACAGACGCCGCCTGATTAGAAAAAGCCGGGAGCTTGGGAAGGAGACGGGATTGAAGAAGCCA
CCCGGCAGGGAGGCCGAACGGCCCAGAGCTCTCCGGGTAAAACCCGCCTGCGGTGATCTGGGAAGTGTG
TCTCCACCTAGCCCTGCGAGCAGCGGCCTTCCTCCCGCCCGTTGAAGGGCGCTGTGCTGGAGTACGAACC
CGGCCCAGAGAAGCCACTCGCCCTTCTTTGTCACTTAAAACCCTGTCCCGACGCGGATCTCACGTCTAGAC
CTCTGTCTTTAAAGCGGATGTAGAGCGCGTTCTAACCGTTCCCTAACCATTGTGTCACCGCGAAAGGCGGG
GCTGTGTGGAACCGTCCCGCACGTGTGCGATGAATCTGGCTCCGCTGAGAACGGATCCGTGGGCTGTCTG
GCGCGGGCTGGGGCAGCAGCCGAGAGTTAGTCTACAGAGCTAGGGCCCGAGGGTGGACCTGCGTCCGCG
TCTCGTCACGAAAGGAAGCTCTTTTGGAGAGGCAAAACGTGGTCGCCCAGATCCGGCGCAGCTGTAGCCG
TGGGCGCTGTGCAGTGACAGCCACACCCGCCACCTGTCACG
400; SW vs SM; chrX: 2845926-2846236; X; ARSD; INSIDE
TTTCTCATCAGGATACAGTTCCAGCGTCGCACAAACCCGAAGGAGGAGTACCAAGAGATGAAAAACAGGC
AGCCCACGCCGGCCATGCCGGTGACTGCTCTCGCGGAGACAGAGAAGAAACCGCAGGCTGGCCGGCAGC
CAGGGTGAGAATCCCCAGCGCCAGGAACTGGGTGTAACCCCAGAGCTGCGCCCTCAGGGCGGCGTCCACT
TCGGGGGGCCTGCCTGGGTCACAGTCGTTTGTGAGCGTGAAGGGCATGCCGTAGAAATAGTCAAATCCGT
GGTTCAGGGGGTGTGGCAGTGATCCCCGCG
TABLE 5
CpG islands potentially involved in progression and death of
disease. Provided for each are: ID; Comparision; Coordinates of selected
regions containing relevant CpG islands based on Homo sapiens full genome
as provided by UCSC (hg18, Mar. 2006); Chromosome; GeneName; Location
relative to gene Sequence.
406; DOD/alive; chr2: 115635091-115637285; 2; DPP10; PROMOTER
AAAAAAGAAATGAGTATCAGAGTCTTATCATCATTACAGTTCTTATGGTTTTTAACCGACCTTTAGGAGTTC
CACCGACGTGACCCAAGCAGCTGGTAGGAGAATCTGGGCTGGATTCGGAAGGCGCGCTACAGGACGCCC
GCTGCCCCGGATCGGAAGGCGCAGCACCTCAGGCCACAATCTCAGACACGCCCTCGGGTCCCGACAGGTG
TTGCCCGCCTCCCACGGGGCTCCGGGACCCCGGTCCCCGGGCTGCCCCCTGCCTTCTGGGGCGCTGGAGC
GCGCGCAGTGGCGGAGCTGAGCCACCCAGTGCTTCGCACGGGCGCGCTCCGCTTCTCCGGGTTTTAGCGG
AAGCCTGCGGGGGGCGGGGTAACCGCGGAAGCCGGCGGCCGTGGGCGCGCGGGTTGGGGGCTCTCGCG
CCGCTCCGGGCTCTCCCCCCCCCCGGCTGCGGTTGCCGAAGAGAGGCCGGAGGCGGCGCCCGGCTGCTC
CACCTGGCGCGCTGAGCACCGCGCGGGGAGCCCCCGGGGGCGGGCGGTGGGGGGCGCGGACTGCGGGA
AGAAGGCACGAGGCGTCGCCGCAGCTCGGTCAGGGGCCGGGGCCCCGCCGCTCGCCGCTGCACTAACTT
GCCGCTTGGTCTCGCCTCCCGCCGCGGCTCGCTGCGCTTTGGGTGGCGGGGGGCGGGGAGAGCGGGGAG
TCAGAGGGTCTGCGGTGGCCGAGGGAGGGACCCTACGACGGGGAGCCCGCCCGGTGCCGCTCTTCTTCC
CCTCCCCGCCCCTCCGCTCCCCCCACCCCGTCCCTTCCGCCGATTCCGGGAGGACGGGCGCCCGTGACCT
GCGAACGCTGCCAAGTGACGGTCCCCGAGTCTGAAGCGCCCGCGAGGAAGCGAGCGCCAGCGCGGGCCG
CCGGCGATGACGGCCGCGAAGCAGGAGCCGCAGCCCACCCCGGGGGCCAGGGCGAGCCAGGCGCAGCC
GGCGGACCAGGTGAGAGCGGCAGCCGCGGCCAGGCCCTCCCGGGAGGGGTGGCTCCAGTGCGCGCTCCG
CCCGCCTCCCGCTTCCCAGGCTGGGCTCCCGCGCCTCCCTCTTCTCACCCTCCCCCGCCCCGCCCCAGTTC
CAGGCTCTCCTGCTTCTCCACGGACTCTGCGGGAAGTTAGAGCCTCTGCTGCGCTCCGGGGCCCGGCGAG
AGGATGCGCAAGGTGGAGAGCCGCGGGGA
407; DOD/alive; chr3: 62330280-62330608; 3; FEZF2; INSIDE
AAAATTGGTGCATTTAGGAAGGAAATGCTATAAACGCCTAATTCCTTCTCGTTCTTTGGGGTTGCTGAGCT
GACCTCGCCGCGAGGGGAGAGGGGGAAAAAAACGCGCACTAATGATTCTGTTTATTAGTTATATATGTAT
ATATTCCGTGTTCGCTTGTACAGGAGGATTTACATGGCTGTATAAAGATGGCTAGGGGCGCCGCGCTCTTC
TGGGGCGCTCACGGTGACAGGCTGGGGTTAAAACTGGCTGCCCCAGGAGAAGCGGAGGCCTGGAATTAA
ATACGTTTCGGCGCACTGATTTAAATAAGTTTCCTGAATATACAAA
408; DOD/alive; chr3: 62331767-62332398; 3; FEZF2; INSIDE
AGAGCTTCCCCCTACACCAGGCACAACCCGATTCTAAAGAAATGCTGCGCCCGCGCCTGCAGATTTCGCCT
TCTCTCTCCAGATCCCTCTTTGCCTTCCTGCCAGCCAGCCGCGACCCGAGTCCTGAGTGAGGTGAGAAGA
GAAGGCCTCGCCTGGCACGTTACCTTTTTGGTGAAAGCCTTTGCCGCAAAATTCGCAGACGAAGGGCTTG
TAGCCCGCGTGGATGCGGATATGCGTGTTGAGCGTGGAGCTGCGGTTGAACGCTTTGCCGCACTGGTTGC
ATTTATGTGGCTTTTCCTAGGAAAGGGGCGAGTGCACAGTAAGGAGAGGCCACCTCGGGAACACCTGGAA
GGGACATCCCCCCCACCCCCACTCAACCCTAGAGGGTAAGGGATAATCTTTGGCCATCGTATCCCCGGTG
TTATCACTAAGATTCTGGGGGTTGCGCGCGGGCTAGGCCCGACCCGGGGGCACGTACCTGGGTGTGGATA
ATTTTGTGCCTGCAGAGCGTGCTGGCCTGGCGAAAGCCTTTGCCGCAGACTTTGCACACGAACGGTCTGG
CTCCGGTGTGGACCGGCATGTGGCGGGTGAGATTATAGTGAGCGTTAAACACCTATGGAAAGACATGG
409; DOD/alive; chr20: 22514762-22515148 20; chr20: 22514762-22515148; Unknown
ATCTTTTGCTGCTGAAATGCAGATGGTTTGGACACTTCATAAAGAGGGCATTAATAAGCCCGCCGAGTGAG
CGCCAGGGCGGGATTCTCCCACAAATTCAAGGTCTGTATCTCCGCGGAAGCCGTGCTATCGGTCCCCCGA
GTGCTGAAGGCTCCCACGAGGGGCAGGCCAGCCCGGTGCGCCAGGGAAGGAGCTTGATGGTGTGTACGG
CTACGTAGTGAACGTGGAGGTGTGCGCAGCGGAGTCAGAGGGGCTAGATCCCCAGCATTTCCCACGGGGT
CCCACCTAGCGCGTGGATGGAGCAACTTCATCACTCCACCGAGGGCAGGGAAAGAGGAGTAAGCATTGGA
GCTCAAAGAATGAGCAATTTTTCAAAGCTTTCTCC
410; DOD/alive; chr20: 22510737-22514165; 20; FOXA2; PROMOTER
CGGGTGGTTGAAGGCGTAGTGGTGTTCCGGCTTCAGGTGGGCCTCAGGCGGCAGGCCCGGGTGGTGGGG
CGGGCCCAGCAGGTGGGCCGCGGCCTGCTGCTGCTGCCCGGGAGAGGGCGCCGGCTCTGGGGGCTCAGC
GCCGCAGCCGGCGTCCCCTTCAGCTCTCCCAGGCCCCCTCGCTTGTGCTCCTGGCACGGGGAGGCGCTCG
AGTGAGGCGACTCGGTGCCCGCCGGAGTCTCGGAGGCCGGCCCGGCGGCCTCCCCGAGTTGAGCCTGTG
AGGCCTGGGCTCCGGCGGCCGCTTCTTGCCGCTGCCGGCGGCGCCTGCGGCCTCCTTCAGCGCCAGCTGC
TTCTCGCACTTGAAGCGCTTCTGGCGGCGCAGGTAGCAGCCGTTCTCGAACATGTTGCCCGAGTCAGGGT
GCAGGGTCCAGAAGGAGCCCTTGCCGGGCTTGTCGGGCGAGCGGGGCACCTTCAGAAACAGTCGTTGAA
GGAGAGCGAGTGGCGGATGGAGTTCTGCCAGCGCTGCTGGTTCTGCCGGTAGAAGGGGAAGAGGTCCAT
GATCCACTGGTAGATCTCGCTCAGCGTCAGCATCTTGTTGGGGCTCTGCTGGATGGCCATGGTGATGAGC
GAGATGTACGAGTAGGGCGCTTTGCGTGCGTGTAGCTGCGCCTGTAGGTCTTGGGGTCGCGGGCGCGGCT
CAGGCCCGCCTGCCCGTACATGGGGCTCATGGAGTTCATGTTGGCGTAGGGGGCCAGGCCGCCCATGGCC
CCGGCCGCCTGCCCCCCGAGCGGGCTCAGGCTGGGACTCAAGTGCGGCCCATGCCCGCCACGCCGGCCG
CCCCGGCCGAGCCGCCCATGCCCGCCATGGCGCCCGCGCCGGGGGACATCCCCGCCAGGGACGGGCTCA
TGCCAGCGCCCACGTACGACGACATGTTCATGGAGCCCGCGCTCATGTTGCCCGAGCCGCTGCCCATGGC
GGCCGCCGACATGCCATGTACGTGTTCATGCCGTTCATCCCCAGGCCGGCGTTCATGTTGCTCACGGAGG
AGTAGCCCTGCGGACAGAGCCCCGGGAGGGAGGCGACAGCGTTAGCACCGCGGCTGGAGGGTGCCCAGA
CCTCCCACCCACCGCCCAGGCCTCCGCGTCCGGGGAGGCCTCCGGGGGCCCTTTCGTCCCCGATGGCCCA
GTCTCCGGACTCCGAGTCTGTTTCATT
411; DOD/alive; chr8: 57520625-57522095; 8; PENK; PROMOTER
ACAGAGGACTTCTCGGGGTTCCCGAATTCCCAGGGTTAAAACAAACTTGGTTTGTGCGGCGACACCGCTA
CCCTTACCGGTCCCCAGATAGTCGCGGATCCCCGAAGCTAAGAGCCAGGGCAGGACTCAGTCAGTGTTCC
AGGAACAGCTGAGACACCCAGGTCACCACGGGCTCGCGCCGCTGCGGCTCCGACCCGGTGCGAACCGCC
ATACGCGCCGCGCGGTGGGCCGGAGGCAGTCCGCGTACTGTTGCGGAAACTCTGTCTCACAAGGTGCGCA
ACACTCGCCGCGCGCAACACCACCAGGAAGTTGATGTCGGCCGGGCGCACTAGGCGGTAGCTGCACGTCG
CGCAATCCTGGCTGCATTCGGCCCGCACGGTCGCCAGGAGCCCGGGGCCGAGCAACAGCAGCCAAGTGC
AAAGTGTCAGGAACCGCGCCATGGACTGCGAGGAGAGAGGGACGCGTGCTTCGGCCTGCCTGGGCGCAG
AACGGGGTCCCTCGGCAGGACCCTCGCCGCGACAGCCTCAGCAGGGGATCGTCGAGCAAAAGCCCGCAG
GAATGCTCCTTTCTGGGGCCCCGCCCTCCCGGCCGACAGCTTTTAGGTAGACGTGGAGGCGACTCAGATC
GCCTCGCGGTTCCCGGGTGGCGCGGTCGCCCCCAACGCGAGGCTGCCTGGGGCACCCGGCTCTTTTCCTG
GGCGTCCGCGGCCCAGGGCAAGATTCCGGAGAGAACGCCGCAGACCAGGGGCGAGAGAGCGGGAGCCG
GGGGAGGCAGGACATTGACTGGGGTCACAAAGAAGAACCAGGGAACGCTGTGGGGAACCCATGCAATGA
AATGTGAAGGGAAAGAGGGCGGGCAGACGTCCCCAAACCCGCTCAGCAAAGACAAGCTTCGGGCAAATTC
ACTCACGTTGACGCTGTTCGGATGGAGCAGGCCAATTGGAAAAGCCGGGTTCAGACACGACTCTAGAGGG
AAGAGAAGAAGGCAGTGTGAGGAGGGCGGGCGTCGGGGAGAAGCGGGCCCGGGTGTGCTGGCGGACGT
AGGGCCTCACCGTCGCGGTCCTCAGCGTCTCTGCGGGGTCACGGGCCAGGCTGCGGGGCTCTGAGCGCC
TGCCTCGCCGTCCCGGGGCTTAACGGCTGCTGGAGCCACTTTATAATTACCCCAAACCGAAGGAGGCGCG
CGCGCCCCAATCGCCGGCGGGCTGCAGCT
412; DOD/alive; chr17: 24303411-24303889; 17; PHF12-SEZ6; DIVERGENT_PROMOTER
GATCTGCTCTTCAAGAGGAAGCCTAAAGTGGAGAGTTTGTAATCCTGACAACGCCCAGCTACCTGCGTACC
CCGGACTCCAACTCCCAGTTTGCAACGCCAAAGGGTCTAAAGGGCGAACGGGGGCGATTGCATCCTGGGA
GCAAGAATCGCGATAGGTCTGATGGATTGTGGGAACTGTAGTTCCATGTGCGTGCGATGCACTCTATGGT
AGGATAGACCCGGGGAAGAGTCATTTGCCGGCCAGGAAGGGATACTTTTGAGAGCGTCAGTGCTGCATGC
CGGGATTTGTAGTCTGAGGCCCGCCTCGCATTCTGGGCGGGGATTCATGCTCCTTTTCAGGGCGCCCGCT
CCTCCCCTTGGTATTGCCGTCAGAGATGGGCGGTTGGTTATTGCTGCCTGATGGTGGATGAAGCAGTGGA
AAAGAGAATTGTATCGTTGTGCTTGACACTAGGGGTTTAGTTGGAATTGTGCTTC
413; DOD/alive; chr1: 149638545-149639227; 1; PSMB4; PROMOTER
TAGGATTACTGCATGTTCAGCTACGACCTCATCAACATGGCTGCTGGAAGTCGTCTACAGGAAAAAGAAAG
AAATGACACTGAAGGATCACTTCCGCTTCCGTTGGCGCAAGCGCTTTCATTTTTTCGCTACCGTGACTAAG
ATGGAAGCGTTTTTGGGGTCGCGGTCCGGACTTTGGGCGGGGGGTCCGGCCCCAGGACAGTTTTACCGCA
TTCCGTCCACTCCCGATTCCTTCATGGATCCGGCGTCTGCACTTTACAGAGGTCCAATCACGCGGACCCAG
TAAGTTCTCGGCGCTTCGTTTGCGTAGCGGGAGGGACCGTGGGGCCTGGTGCTGCCGGCTGGTTTTGAGA
GCCCGGGAAGGTGAGGCGGGGACCCCGGGGGCGCGCGAACGGCAGGGGAGCTCAGGGCGCGGAGTCCT
GGAGAATGCAGAATAATTGGAAGGAATTATAGAAAATCAGAAGCGCAGCTAGTGCGCGGAAAGAGGGCGC
AGTCCATCCCCCCTCTCAGCTCCCACCGTTCTCACTCTTTAGGAACCCCATGGTGACCGGGACCTCAGTCC
TCGGCGTTAAGTTCGAGGGCGGAGTGGTGATTGCCGCAGACATGCTGGGATCCTACGGCTCCTTGGCTCG
TTTCCGCAACACTCTCGCATTATGCGAGTCAACAACAGTACCATGCT
414; DOD/alive; chr21: 36990008-36995832; 21; SIM2; PROMOTER
TCCTTAGTGACAAGGTCTCTGATCTCCTGCTGCCACTGCAATAGCCTCTCCCATCCCGCGGGGAACGGCCG
GAGTTCTTCCCTTGATCTCTCCCGAGTCGGCTTCCGCTGGGGATGGATCGCAGGTAGCGCCGGCGCGGCC
TGGGGAAGAACAGTTGCGGAGCATCTGAAGCGGAAAATCCAAGCAGATGTGAGGCGATCCGGGCCCGCC
TCGTTCCTCTTGGGGCCTGAATTTCTTCCAGATAAGTTTCCTAATGGAACATTTCTAAGAGGTGGGGTACG
AGGCGGCTTGCTCGCACGGCAGTGGGACAGACTGCGGGTGGGGACGTACTGAGAGGTCCGGACCTCAAT
GCGTCCGACCCGTCTCCACACCGCCCTTTTCCAGCCCCCAGTCTCCTTTCATTCCCTACTCTTCAGGCTCC
TTTGGGGCCAGTGGGTGAACCGCCATTTAGAACGGTGCCTCGGACTCGGGGTCGTGCGCTCCATCTCTGC
CTCCCCCCTGGGGCCCGCGAGGCTGGTCCGGGCTTTCTGAGCTGGGCGTTCGGCTTTAGGCCCAATACCT
GGACCAGGAATTTCTTCTCCCCGCGCCAGAAGGGAAAGACATAGGAGGTGTCCCAATCTGCGGTCACCGC
CGATGCTCCTGACACTCTAGTGAGCACCTGCCCGGTACTTTTCCATTCCAACAGAGCTTCCAGCTTCATAC
TAACTATCCCACATACGGCCTGTGGGTATTAGCTCTAAGTGTCCTTTTCCGAGGGCCCGAGGCTCCCCCTC
CAGCAGGGAGAGCTCCGGGACGGCCCCCACCAAGGGTTGGGTTCTTCCTTCACAATTCCACAGAGGCATC
CCTGTCCTTCCTACCTGGGAAACCTCGAGGTGCGGTGCCCGTGTACTTCTGGTACTTTGCGTGGTGCCATC
AGGGACCCCAGAGCCACAGCTGCGTGTGTGTGTGGATGTGTGTGTGTGTGTGCGCGCGCGCGCGTGTACG
GCGAAGGATGTGCTTGGGGGAGCCGAGTACACAACGTCTGCTTGGGCAGCTGCTGGGCAGGCGTTGGGC
CTGGAGGTATCTCACACCCACGTATCTTCCAGTCTTCAAACACGGCATTGCTCTGCCTCCCGTAGCGCGCT
TCGAACCTGCCTCGCGGACACGTGAACAGAGGCTGCCCTGGGAAGATAAGTGCGCTTTCCCGTAAAATCC
GGGAAATTTGCCTTG
415; DOD/alive; chr1: 232106869-232108183; 1; SLC35F3; PROMOTER
AAGTACTGAACTGGGAGCGGCAGGGTTTGAGTCAAAAGAGAAGGGTGGAGGAGCGCGTCCGGTGCCCCA
AGGCTTCCAGGCGGAGCGCGGGCGCGAGGTGCGGGCTCCGGGGCGGAGCGCACGCCCGGAGGCGGGAA
GTGGGCAGCAGCGCCCCCGCCTGGCCCCTGTGCGCCCCGACCCGACGCCTCCCCGCCCGACCAGGTGCCT
CGAGAGCGCACAGCTGGGAGGGCTCTCCCGGTCGCGGCGAGACTCACGCCTGCGGTGTGCTAGGGCGGC
GGCGACGGTGACGGGCGTGGGGCCGGCGCTGCCTCGGCTGCCGGGTCGTTGCGGCGAGCGCGCGGGCC
GGCCTGGAGTCACCGGGCTGAACCGCCGCGCCTGCATCGTGCCGCACGCCGCGGAGGCGCTCGGGTACA
GACCGCGCGGGCGCGCACAAAGCGGCCCGGGGCGGCCGGCGCGGCGCAGACCCTCGGTGGCAGCGCACT
CCAGTCTTCCCAGGCTAGCGGCTGCAGGGAGCTCCGGCCCGCGGCCCCTCCGCCTCAAGTCTGGGAGCTG
CCGGTCCCACTCTGTCTTTGCCTATGGGGATTCGAGAGTTTCCCAGCGGCGCACCCAGGGGCAAGAGCAT
TGCCGTGTGAGTAGCGCCCCGGCGTGGGTGAGCGAGCCGGCGGGCGGGAGGCCGGAGCGCCGGGGTAG
CCCTTTGCAGCTGGGACACTGGGCAGTCTGAGGCTCGGGGAAGGGCGGCGCGCGCGGTGGAGCTGCTCG
GGAAGTTTCAGTCATTCTTTCCCTCGCCACTCGCCCCAACCCGCACTGCCCCGAGAGCCCAGGATAGGGC
ACTGGGGACAGCTGCCCGGGGAAGTGGGTGAGTGGCGGCGGGAAGGGAGGAGCGCGGGCTCTGCCGCG
GCGCTCGCCCCCGGAGGGCCCCGGCCGCGCTCTTGCTCTCGCCCTGGGATCTGCTCCTCACGAATCCCCT
CCTCTCTGTCCATGCTCCCCTGCCCACCCACCTGCCCGTGGCGCCTGCGACCGCAGTGGCATGAGGAGGT
CACCGGACGTCAGCCCCCGGAGACTGTCCGACATCAGCCCCCAGCTCCGGCAGCTCAAGTACTTGGTGGT
GGACGAGGCGATTAAGGAGGATCTGAAATGGTCGCGCTCCGTGGAGGATCTCCCAGCGGGCCGGTGGGG
CTCACGTCCATCGAGGAGCGGATCCTGCGCATC
416; DOD/alive; chr6: 21704622-21705099; 6; SOX4; INSIDE
TGCATCACCACCTTGGTTTTGTTTTATTTTGCTTCTTGGTCAAGAAAGGAGGGGAGAACCCAGCGCACCCC
TCCCCCCCTTTTTTTAAACGCGTGATGAAGACAGAAGGCTCCGGGGTGACGAATTTGCCGATGGCAGATG
TTTTGGGGGAACGCCGGGACTGAGAGACTCCACGCAGGCGAATTCCCGTTTGGGGCTTTTTTTTCCTCCCT
CTTTTCCCCTTGCCCCCTCTGCAGCCGGAGGAGGAGATGTTGAGGGGAGGAGGCCAGCCAGTGTGACCGG
CGCTAGGAAATGACCCGGAACCCCGTTGGAAGCGCAGCAGCGGGAGCTAGGGGCGGGGGCGGAGGAGGA
CACGAACTGGAAGGGGGTTCACGGTCAAACTGAAATGGATTTGCACGTTGGGGAGCTGGCGGCGGCGGC
TGCTGGGCCTCCGCCTTCTTTTCTACGTGAAATCAGTGAGGTGAGACTTCCAGAC
417; p-np; chr1: 160220156-160220709; 1; OLFML2B; INSIDE
TTGGGGTTGTAGTCTATCTGGGTCGTATAGGAATACTCATTCTCGAACAGCAGCCTGGGGACGATCTGTGT
GTTGGTGTGGGTGTCGAAAGCGTAGGAGATGTTGGCATTCCGCTGGTTGTAGCTATCACGGCATACAGCA
CCCCACAGATGACGAAGCAGTTGCCGTAGAAATTCCTCCGGAGCCCCGTGCGCCATGTGGTCTCCTTCTG
TGTGCTCAGGTCCGCGGCATTGAGCTTGCTCAGGACAATGACCTCCTGGCTGAAGCCCTCATCGTCCAGG
GCCGGGTAGATGAGCCATGGCCATTCTCGTCCACAGCAAAGTCCACGTCTGAGTGGCCCTGCCATCGCCA
GGGGGTGGCCTCCTCGTAGGCCACGTCATGCAGCATGGCCCAGGCAGCCACGTAGCGCTGCTTCAGGTCG
TACTTGATGATGTTGCGGGTGAAGGCGCGATTGTAGTAGAAGGCGCCATTTATACCACGTGGCCTGTGCC
GATCCAGCTGTACGGGAGCTTGTAGGAATTGCTCCAGCGACCTGCAGGTGGGGAGAAAAC
418; p-np; chr3: 129688131-129694023; 3; GATA2; INSIDE
TCACAGGCCAGCTGGAAGTGGGCAGAAACCCTGTGGGTCCCAGACCCTCCCCAATCGGCCGCTGCTCCCA
CCTCTCCCGCCCCAATTTTTCAGCAGCTCGATTCCTGCGGATCCTACATCCGGGAAGAAGCAGACGGGCC
CTCCTCCCCTCCCTCGCCTGGCGCGCGGCGCCTGGGTTCTCATCACCACGGGCCCAGTGCTCACCGTGCG
CGGGGCTGTAGGAGACGCGCGCCCGCGCGTGAGCGGGGTTGGCATAGTAGGGGTTGCCCTGCGAGTCGA
GGTGATTGAAGAAGACGTCCCCTCGTCTGGAGGCAGCAGCTGCGCGGGTTCCATGTAGTTGTGCGCCAGG
CCCGGGTGGTGTGAGTCGGGGTGCTGCGCATTCAGCACGGCCGGGTGCGCCATCCAGCGCGGCTGCTCG
GGCGCCACCTCCATGGCCGGCGGCGGCGGCTCAGGGTCTGGGTGCAGACGGCACGGCCCTGCGCGAGGA
AGGGGGAGTGAGGCGTGCCGCCAGCGCCTGACACCCCCCAAAGTCCCACCACGAGGTGTCCCGCACGCC
ACGGAGCCCCAGCCCAGATCCGGCGAGAAAGAGCACCAGTCCCGGGTGGGAGGAAAGCCCAAGGCTCAA
AACGAAAGGAAGGCGGGGAGGGGGTTCAGCCACGCACACTCACGTGGTGACCCGCGGCTCCAGAATCAC
ACACCCGTGCACATGGGGTCACGCCCGGGGACGGGTCCCGACACCAGTGACCCCAACAAACGCACAGAG
CAGCACTTCAGTCAGACACTCACACTGAGCCCCCCCGCCCGGTAGACAAACAATGAACACAGACTCAAAA
GTTGGAGACAGGCGCCCGGGCACCCAGTGTGGCACTTGATCCCAGCGACACGCACACACCCACACTTGGC
GCCAGATACACATACTGATCTCAACCCCGAAAACATGCACACGCAGCCCCCTGAGCGCAGTACTAAGCGG
CACAATCAGGACCTTCAACAAAGCACACCAAAGCAGTCGCCCGCAGCCTGGCCCCCCGCCCTAAGTCCCC
CCAGAGTCCCCTCAAAGCTAGGAGCGCCCCAGGCCCCCAGCCGGCTCTCAAACCCCAAACTTACACACGC
AGCCGTGGGGAGGGGAGGGACTCGGCCTCTGAGAGTGAAGGAGTTCGGCGGGAGCCCCGAGGGCGACG
GGCCCAGGGACAGCACGTCCGGAGGCTG
419; p-np; chr6: 26312699-26313302; 6; HIST1H4E; INSIDE
GTCTGATCTGTGAAGGGTAGGGCCAGCAGGCAGCACCAAAGTTCCCGTATGCGCGTTTTCAGTCTTCATTT
AGGTCCGAATTCCCGGCATATAAGAATACTACCGTCGCTTGTTTTTCAGATTTTTGGGCTATTTTCGTTGGT
GTGTTGGTCATGTCTGGTCGCGGCAAAGGCGGAAAGGGACTGGGTAAAGGAGGCGCTAAGCGTCACCGT
AAGGTCCTGCGAGATAACATCCAGGGCATTACCAAGCCTGCCATCCGGCGCCTTGCTCGTCGCGGGGGTG
TCAAGCGCATTTCTGGTTCATCTACGAGGAGACTCGCGGGGTTCTGAAGGTGTTTCTGGAAAACGTGATTC
GTGATGCTGTGACTTACACGGAGCACGCCAAACGCAAGACAGTGACAGCGATGGATGTGGTCTACGCGCT
GAAGAGACAGGGACGCACTCTTTACGGCTTCGGCGGCTAATGCTACCGTTAAACGACTCAGCATCTCGAC
TTCCCAAATCAAAGGCCCTTTTCAGGGCCGCCCACAGTTTTCCGCAAAAGAGCTCATGACTTGTTAGACGA
TTGGTTGGTCTCTTTATAAGTTAATTGTTCCTGTCAA
TABLE 6
Primers and probes for MEIS1 MS-SnapShot.
BSP Primers (MEIS1)
Fwd. 5′
GGGTTTTTAGAGGTTAGGGGAA 3′
Rev. 5′
CAACTAAATAACCAAACCTCTCCTC
3′
MEIS1 A/B SNAPSHOT Probes
Size
Probe Sequence (5′-> 3′) (bp) Strand UM MT μM*
MEIS1 A T21 GGAGAGGGGGGTTATG 45 sense T C 0.2
ATGTTAGG
MEIS1 B T14 GTTTGTTTGGTTTTAG 34 sense T C 0.2
AGAA
TABLE 7A
Differentially labeled CGIs between subgroups relative to blood
CGI Gene Name Probe location Subgroup
chr01-2072175- PRKCZ chr01: 002072146-002072190 NMI-mt vs Ref
chr01-2106293-2106715 PRKCZ chr01: 002106497-002106541 MI vs Ref
PRKCZ chr01: 002106664-002106715 NMI-wt vs Ref
chr01-47672249-47672972 FOXD2 chr01: 047671905-047671953 NMI-wt vs Ref
FOXD2 chr01: 047672191-047672235 NMI-mt vs Ref
FOXD2 chr01: 047682633-047682689 MI vs Ref
chr1: 63554983-63563059 FOXD3 chr01: 063559476-063559520 NMI-mt vs Ref
FOXD3 chr01: 063559476-063559520 NMI-wt vs Ref
chr01-68288825-68289104 DIRAS3 chr01: 068289060-068289104 NMI-wt vs MI
DIRAS3 chr01: 068290072-068290116 NMI-wt vs Ref
chr01-71284766-71286392 PTGER3 chr01: 071284980-071285024 NMI-wt vs Ref
chr1: 90955098-90955445 BARHL2 chr01: 090955137-090955181 NMI-mt vs Ref
chr01-119333484-119333719 TBX15 chr01: 119333484-119333528 NMI-wt vs MI
TBX15 chr01: 119333569-119333613 NMI-wt vs Ref
chr1: 163590111-163590435 LMX1A chr01: 163590167-163590226 NMI-wt vs Ref
chr1: 173258989-173259419 MRPS14 chr01: 173259418-173259462 NMI-mt vs MI
chr01-178464743-178471598 LHX4 chr01: 178470479-178470532 NMI-wt vs Ref
LHX4 chr01: 178470597-178470641 NMI-wt vs MI
LHX4 chr01: 178470597-178470641 NMI-wt vs NMI-
mt
chr1: 196153712-196154414 LHX9 chr01: 196154203-196154247 NMI-wt vs Ref
chr1: 219117072-219117487 HLX1 chr01: 219117515-219117568 NMI-mt vs Ref
HLX1 chr01: 219121301-219121352 MI vs Ref
HLX1 chr01: 219134113-219134157 NMI-wt vs Ref
chr1: 241719037-241719368 SDCCAG8 chr01: 241719439-241719492 NMI-wt vs Ref
chr02-19424445-19425131 OSR1 chr02: 019415391-019415435 NMI-mt vs Ref
OSR1 chr02: 019424965-019425009 NMI-wt vs Ref
chr02-45249374-45251726 SIX3 chr02: 045013420-045013464 NMI-wt vs Ref
SIX3 chr02: 045015982-045016033 MI vs Ref
SIX3 chr02: 045015982-045016033 NMI-mt vs Ref
SIX2 chr02: 045085251-045085298 NMI-wt vs Ref
chr2: 54536404-54537878 SPTBN1 chr02: 054536311-054536361 NMI-wt vs Ref
chr02-63134470-63134933 OTX1 chr02: 063134470-063134515 MI vs Ref
OTX1 chr02: 063134470-063134515 NMI-mt vs Ref
OTX1 chr02: 063134803-063134847 NMI-wt vs Ref
chr02-66525936-66527222 MEIS1 chr02: 066525898-066525942 MI vs Ref
MEIS1 chr02: 066526023-066526067 NMI-mt vs Ref
MEIS1 chr02: 066526791-066526835 NMI-wt vs Ref
chr02-70984709-70985764 VAX2 chr02: 070985519-070985563 MI vs Ref
VAX2 chr02: 070985519-070985563 NMI-wt vs Ref
chr02-72224630-72228512 CYP26B1 chr02: 072227412-072227461 NMI-wt vs Ref
CYP26B1 chr02: 072227537-072227583 NMI-wt vs MI
chr2: 73004709-73005568 EMX1 chr02: 073004783-073004827 NMI-wt vs Ref
chr2: 85213468-85216104 TCF7L1 chr02: 085215511-085215555 NMI-wt vs Ref
TCF7L1 chr02: 085216153-085216212 NMI-mt vs Ref
chr02-105864220-105865009 NCK2 chr02: 105864372-105864417 NMI-wt vs Ref
NCK2 chr02: 105864443-105864487 NMI-mt vs Ref
NCK2 chr02: 105864906-105864950 MI vs Ref
chr02-111591678-111597436 FLJ44006- chr02: 111592037-111592081 NMI-mt vs Ref
BCL2L11
FLJ44006- chr02: 111593125-111593170 NMI-wt vs Ref
BCL2L11
chr02-115635091-115637285 DPP10 chr02: 115636612-115636656 NMI-wt vs Ref
chr2: 119329502-119332035 EN1 chr02: 119330694-119330738 NMI-wt vs Ref
chr02-156892636-156892878 NR4A2 chr02: 156892639-156892683 MI vs Ref
chr02-156893736-156894685 NR4A2 chr02: 156894489-156894533 NMI-mt vs Ref
NR4A2 chr02: 156894576-156894620 NMI-wt vs Ref
chr02-171384729-171385226 GAD1 chr02: 171384729-171384773 MI vs Ref
GAD1 chr02: 171385019-171385063 NMI-mt vs Ref
GAD1 chr02: 171385019-171385063 NMI-wt vs Ref
chr2: 172653235-172653630 MAP1D chr02: 172653288-172653332 NMI-wt vs Ref
chr2: 174907710-174910885 FLJ46347 chr02: 174910857-174910905 NMI-wt vs Ref
chr2: 176652334-176656692 EVX2 chr02: 176655532-176655591 NMI-mt vs Ref
EVX2 chr02: 176656139-176656183 NMI-wt vs Ref
EVX2 chr02: 176656517-176656563 MI vs Ref
chr2: 176720618-176720921 hsa-mir-10b chr02: 176720535-176720594 NMI-mt vs Ref
hsa-mir-10b chr02: 176720535-176720594 NMI-wt vs Ref
chr02-176737610-176738187 HOXD3 chr02: 176737609-176737653 NMI-mt vs Ref
HOXD3 chr02: 176737609-176737653 NMI-mt vs MI
HOXD3 chr02: 176738050-176738094 NMI-wt vs Ref
CENTG2 chr02: 236438664-236438711 NMI-wt vs Ref
chr3: 11721578-11721824 VGLL4 chr03: 011721492-011721547 NMI-wt vs Ref
chr3: 12983649-12984210 IQSEC1 chr03: 012983600-012983644 NMI-wt vs Ref
chr3: 25680561-25681574 TOP2B chr03: 025681366-025681410 NMI-wt vs Ref
chr03-129688131-129694023 GATA2 chr03: 129692644-129692688 MI vs Ref
GATA2 chr03: 129698463-129698509 NMI-wt vs Ref
chr03-148591199-148594390 ZIC4 chr03: 148592447-148592499 NMI-wt vs Ref
chr3: 148613030-148613264 ZIC1 chr03: 148613058-148613102 NMI-mt vs Ref
ZIC1 chr03: 148619483-148619541 NMI-wt vs Ref
chr4: 4910534-4911092 MSX1 chr04: 004910620-004910670 MI vs Ref
MSX1 chr04: 004910620-004910670 NMI-mt vs Ref
MSX1 chr04: 004910620-004910670 NMI-wt vs Ref
chr4: 30330303-30333940 PCDH7 chr04: 030333744-030333788 NMI-mt vs Ref
PCDH7 chr04: 030333834-030333878 NMI-wt vs Ref
chr4: 41678680-41678940 WDR21B chr04: 041678597-041678646 NMI-wt vs Ref
chr4: 85636684-85639823 NKX6-1 chr04: 085637474-085637518 NMI-wt vs Ref
chr4: 94974810-94975333 ATOH1 chr04: 094974874-094974918 NMI-wt vs Ref
chr04-111780013-111780343 PITX2 chr04: 111780048-111780092 NMI-mt vs Ref
PITX2 chr04: 111780288-111780343 NMI-wt vs Ref
PCDH10 chr04: 134291474-134291518 NMI-wt vs Ref
NR3C2 chr04: 149586403-149586447 NMI-wt vs Ref
TRIM2 chr04: 154436244-154436288 NMI-wt vs Ref
chr04-155881084-155881434 LRAT chr04: 155881084-155881128 NMI-wt vs Ref
LRAT chr04: 155881330-155881378 NMI-wt vs MI
HAND2 chr04: 174687934-174687985 NMI-wt vs Ref
chr4: 184255825-184258373 FLJ30277 chr04: 184255924-184255968 NMI-wt vs Ref
chr5: 360287-360592 PDCD6 chr05: 000360593-000360637 NMI-wt vs Ref
chr5: 1161803-1162051 SLC12A7 chr05: 001162056-001162100 NMI-wt vs Ref
chr5: 3647468-3656054 IRX1 chr05: 003654466-003654525 NMI-wt vs Ref
chr5: 5192442-5193941 ADAMTS16 chr05: 005192514-005192558 NMI-wt vs Ref
chr5: 6790705-6791004 POLS chr05: 006790682-006790728 NMI-wt vs Ref
chr5: 54554812-54555385 UNG2 chr05: 054555175-054555219 NMI-wt vs Ref
UNG2 chr05: 054555391-054555442 NMI-mt vs Ref
chr5: 114542616-114544119 TRIM36 chr05: 114542773-114542817 NMI-wt vs Ref
chr05-115810975-115811393 SEMA6A chr05: 115811349-115811393 NMI-wt vs Ref
chr5: 127899858-127900162 FBN2 chr05: 127900012-127900056 NMI-wt vs MI
FBN2 chr05: 127900012-127900056 NMI-wt vs NMI-
mt
FBN2 chr05: 127900101-127900154 NMI-wt vs Ref
chr05-134390896-134393045 PITX1 chr05: 134390896-134390940 MI vs Ref
PITX1 chr05: 134390896-134390940 NMI-wt vs Ref
PITX1 chr05: 134391093-134391137 NMI-mt vs Ref
TRPC7 chr05: 135720277-135720321 NMI-wt vs Ref
Chr05-140724146-140724826 PCDHGA5 chr05: 140724562-140724606 NMI-wt vs Ref
chr5: 140780945-140781256 PCDHGA11 chr05: 140781192-140781236 NMI-wt vs Ref
PCDHGA12 chr05: 140791316-140791360 NMI-mt vs Ref
PCDHGA12 chr05: 140791441-140791494 NMI-wt vs Ref
chr5: 141235749-141238152 PCDH1 chr05: 141237048-141237094 NMI-wt vs Ref
chr05-174091287-174092335 MSX2 chr05: 174091297-174091341 NMI-wt vs Ref
MSX2 chr05: 174091410-174091454 MI vs Ref
MSX2 chr05: 174091473-174091517 NMI-mt vs Ref
chr6: 1326743-1330210 FOXF2 chr06: 001329813-001329866 NMI-mt vs Ref
FOXF2 chr06: 001329813-001329866 NMI-wt vs Ref
chr06-1549606-1560865 FOXC1 chr06: 001551371-001551415 NMI-mt vs Ref
FOXC1 chr06: 001551429-001551473 NMI-wt vs Ref
FOXC1 chr06: 001551500-001551559 MI vs Ref
chr6: 5947471-5950124 NRN1 chr06: 005947569-005947613 NMI-wt vs Ref
chr6: 10498025-10498551 TFAP2A chr06: 010498473-010498517 MI vs Ref
TFAP2A chr06: 010498473-010498517 NMI-wt vs Ref
TFAP2A chr06: 010498811-010498870 NMI-mt vs Ref
chr6: 22677564-22678684 HDGFL1 chr06: 022677587-022677632 MI vs Ref
HDGFL1 chr06: 022677587-022677632 NMI-mt vs Ref
HDGFL1 chr06: 022677587-022677632 NMI-wt vs Ref
chr6: 25834434-25834701 HIST1H2AA chr06: 025834650-025834695 NMI-wt vs Ref
HIST1H2BA chr06: 025840937-025840981 NMI-wt vs Ref
chr6: 41176454-41177326 NFYA chr06: 041177112-041177165 NMI-wt vs Ref
chr6: 50895246-50896050 TFAP2B chr06: 050896068-050896112 NMI-wt vs Ref
chr6: 75968300-75968853 COL12A1 chr06: 075968669-075968713 NMI-wt vs Ref
chr06-101023927-101024343 SIM1 chr06: 101024299-101024343 NMI-mt vs Ref
SIM1 chr06: 101024299-101024343 NMI-wt vs Ref
chr6: 101953488-101953856 GRIK2 chr06: 101953514-101953560 NMI-mt vs Ref
GRIK2 chr06: 101953514-101953560 NMI-wt vs Ref
chr6: 108592365-108597232 NR2E1 chr06: 108595517-108595561 NMI-wt vs Ref
chr6: 126122028-126122524 HEY2 chr06: 126122132-126122176 NMI-wt vs Ref
chr6: 166499964-166503413 T chr06: 166502963-166503011 NMI-wt vs Ref
chr6: 169801163-169801511 WDR27 chr06: 169801059-169801108 NMI-wt vs Ref
chr7: 1029023-1029492 hsa-mir-339 chr07: 001029489-001029533 NMI-wt vs Ref
chr07-2082782-2083345 MAD1L1 chr07: 002083155-002083200 MI vs Ref
MAD1L1 chr07: 002083155-002083200 NMI-wt vs Ref
MAD1L1 chr07: 002121288-002121332 NMI-mt vs Ref
chr07-2724511-2724848 AMZ1 chr07: 002724511-002724555 MI vs Ref
AMZ1 chr07: 002724511-002724555 NMI-wt vs Ref
AMZ1 chr07: 002724629-002724673 NMI-mt vs Ref
chr07-8449587-8450236 NXPH1 chr07: 008449587-008449636 NMI-mt vs Ref
NXPH1 chr07: 008449587-008449636 NMI-wt vs Ref
NXPH1 chr07: 008450192-008450240 MI vs Ref
chr7: 19113449-19113833 TWIST1 chr07: 019113860-019113907 NMI-wt vs Ref
chr7: 27149139-27152087 HOXA5 chr07: 027150566-027150625 MI vs Ref
HOXA5 chr07: 027151311-027151355 NMI-mt vs Ref
chr07-27164708-27165039 HOXA7 chr07: 027164869-027164913 MI vs Ref
HOXA7 chr07: 027164869-027164913 NMI-mt vs Ref
HOXA7 chr07: 027164944-027164988 NMI-wt vs Ref
chr7: 27170441-27172987 HOXA9 chr07: 027170467-027170515 NMI-mt vs Ref
HOXA9 chr07: 027170467-027170515 NMI-wt vs Ref
HOXA9 chr07: 027170998-027171042 MI vs Ref
chr7: 27198331-27199622 HOXA11 chr07: 027198283-027198327 NMI-wt vs Ref
chr07-27219187-27220360 EVX1 chr07: 027245650-027245694 NMI-wt vs Ref
chr07-27251165-27252762 EVX1 chr07: 027251482-027251527 MI vs Ref
chr7: 35263447-35264743 TBX20 chr07: 035263668-035263712 NMI-wt vs Ref
chr7: 96469320-96469736 DLX6 chr07: 096469212-096469266 NMI-mt vs Ref
DLX6 chr07: 096469526-096469572 MI vs Ref
DLX6 chr07: 096469776-096469827 NMI-wt vs Ref
chr07-96488158-96489591 DLX5 chr07: 096489129-096489173 NMI-mt vs Ref
DLX5 chr07: 096489475-096489520 MI vs Ref
DLX5 chr07: 096489536-096489591 NMI-wt vs Ref
chr7: 119702299-119702721 KCND2 chr07: 119702676-119702723 NMI-wt vs Ref
chr07-121727243-121727884 FEZF1 chr07: 121727241-121727285 NMI-wt vs MI
FEZF1 chr07: 121727336-121727380 NMI-wt vs Ref
chr07-155288454-155292175 SHH chr07: 155291537-155291581 MI vs Ref
SHH chr07: 155291593-155291637 NMI-mt vs Ref
SHH chr07: 155291751-155291795 NMI-wt vs Ref
chr7: 158509937-158510390 VIPR2 chr07: 158509989-158510033 NMI-wt vs Ref
chr08-9798161-9799053 hsa-mir-124a-1 chr08: 009798455-009798508 NMI-wt vs NMI-
mt
hsa-mir-124a-1 chr08: 009798593-009798644 NMI-wt vs Ref
hsa-mir-124a-1 chr08: 009800023-009800077 NMI-wt vs MI
chr8: 10624024-10624296 SOX7 chr08: 010624244-010624300 NMI-mt vs Ref
SOX7 chr08: 010624319-010624366 NMI-wt vs Ref
chr8: 11597006-11600365 GATA4 chr08: 011599544-011599588 NMI-wt vs Ref
chr8: 25955253-25955609 EBF2 chr08: 025955446-025955495 NMI-mt vs Ref
EBF2 chr08: 025955446-025955495 NMI-wt vs Ref
chr8: 55532724-55535078 SOX17 chr08: 055533948-055533992 NMI-wt vs Ref
chr08-65661156-65662687 BHLHB5 chr08: 065661235-065661282 NMI-wt vs MI
BHLHB5 chr08: 065662258-065662302 NMI-wt vs Ref
chr8: 72916429-72917309 MSC chr08: 072917197-072917241 MI vs Ref
MSC chr08: 072917336-072917380 NMI-wt vs Ref
chr8: 140700279-140700514 KCNK9 chr08: 140700520-140700564 NMI-wt vs Ref
chr08-142288380-142288718 SLC45A4 chr08: 142288398-142288442 NMI-mt vs Ref
SLC45A4 chr08: 142288610-142288657 MI vs Ref
SLC45A4 chr08: 142288610-142288657 NMI-wt vs Ref
chr8: 145014900-145015187 EPPK1 chr08: 145015195-145015240 NMI-wt vs Ref
chr9: 959530-963276 DMRT3 chr09: 000959621-000959665 NMI-wt vs Ref
chr9: 21979774-21980108 CDKN2A chr09: 021979951-021979995 NMI-wt vs Ref
chr9: 23812413-23812667 ELAVL2 chr09: 023812373-023812424 NMI-wt vs Ref
chr9: 37024136-37028341 PAX5 chr09: 037024964-037025008 NMI-wt vs Ref
chr9: 101621613-101627382 NR4A3 chr09: 101627386-101627439 NMI-wt vs Ref
chr10-7489383-7495345 SFMBT2 chr10: 007491431-007491476 NMI-wt vs Ref
SFMBT2 chr10: 007491576-007491626 NMI-wt vs NMI-
mt
chr10: 13556172-13556753 C10orf30 chr10: 013556159-013556211 NMI-wt vs Ref
chr10: 15294605-15294858 C10orf38 chr10: 015294592-015294641 NMI-wt vs Ref
chr10-21828640-21829645 C10orf114 chr10: 021828885-021828929 NMI-wt vs Ref
C10orf114 chr10: 021828954-021828998 NMI-mt vs Ref
C10orf114 chr10: 021829373-021829417 MI vs Ref
chr10: 76825135-76839606 ZNF503 chr10: 076834917-076834976 NMI-wt vs Ref
ZNF503 chr10: 076837381-076837425 NMI-mt vs Ref
chr10: 88112905-88117344 GRID1 chr10: 088115612-088115656 NMI-wt vs Ref
chr10: 94441310-94441717 HHEX chr10: 094441395-094441439 NMI-mt vs Ref
HHEX chr10: 094441744-094441795 NMI-wt vs Ref
chr10: 99068802-99071038 FRAT1 chr10: 099070245-099070298 NMI-wt vs Ref
FRAT1 chr10: 099070376-099070420 NMI-mt vs Ref
chr10: 101277153-101277910 NKX2-3 chr10: 101277900-101277957 NMI-wt vs Ref
chr10: 102974173-102980053 LBX1 chr10: 102975940-102975999 NMI-wt vs Ref
LBX1 chr10: 102976227-102976273 NMI-wt vs MI
LBX1 chr10: 102976227-102976273 NMI-wt vs NMI-
mt
chr10: 106389558-106392802 SORCS3 chr10: 106392567-106392611 NMI-wt vs Ref
chr10: 124891898-124892607 HMX2 chr10: 124892023-124892067 NMI-wt vs Ref
chr10: 128863581-128864054 FLJ45557 chr10: 128864100-128864145 NMI-wt vs Ref
chr11: 22319439-22319953 SLC17A6 chr11: 022319657-022319701 NMI-wt vs Ref
chr11: 31776637-31777992 PAX6 chr11: 031776609-031776653 NMI-wt vs Ref
chr11: 68274244-68274755 MTL5 chr11: 068274304-068274348 NMI-mt vs Ref
chr11: 117983446-117987106 PHLDB1 chr11: 117984800-117984844 NMI-wt vs Ref
chr12: 1844001-1845219 CACNA2D4 chr12: 001844114-001844158 NMI-wt vs Ref
chr12: 40253533-40253742 PDZRN4 chr12: 040253480-040253529 NMI-wt vs Ref
chr12: 52726910-52727810 HOXC4 chr12: 052727781-052727833 NMI-mt vs Ref
HOXC4 chr12: 052727781-052727833 NMI-wt vs Ref
chr12: 79634857-79635257 MYF5 chr12: 079634813-079634857 NMI-wt vs Ref
chr12-94776044-94776377 SNRPF chr12: 094776044-094776094 NMI-wt vs Ref
chr12: 95164929-95165298 ELK3 chr12: 095165171-095165220 NMI-wt vs Ref
chr12-113657930-113659205 TBX5 chr12: 113325125-113325174 NMI-wt vs Ref
chr12: 113609113-113609535 TBX3 chr12: 113609153-113609207 MI vs Ref
TBX3 chr12: 113609259-113609303 MI vs NMI-wt
chr13-34950488-34951119 MAB21L1 chr13: 034950488-034950532 MI vs Ref
MAB21L1 chr13: 034950709-034950765 NMI-wt vs Ref
MAB21L1 chr13: 034950955-034950999 NMI-mt vs Ref
chr13: 35817738-35819004 SPG20 chr13: 035817882-035817927 NMI-mt vs MI
chr13: 57101588-57102323 PCDH17 chr13: 057101685-057101729 NMI-wt vs Ref
PCDH17 chr13: 057105585-057105629 NMI-mt vs Ref
chr13-94152191-94153185 SOX21 chr13: 094152286-094152330 MI vs Ref
SOX21 chr13: 094152463-094152507 NMI-mt vs Ref
SOX21 chr13: 094152463-094152507 NMI-wt vs Ref
chr13: 105943410-105943788 EFNB2 chr13: 105943362-105943406 NMI-mt vs Ref
EFNB2 chr13: 105943488-105943532 NMI-wt vs Ref
chr13: 111763361-111764235 SOX1 chr13: 111764262-111764315 NMI-wt vs Ref
chr13: 112249708-112249928 TUBGCP3 chr13: 112249984-112250030 NMI-wt vs Ref
chr14: 19992581-19993863 APEX1 chr14: 019993551-019993604 NMI-mt vs MI
chr14: 23710894-23712060 REC8L1 chr14: 023711936-023711980 NMI-mt vs Ref
chr14: 28317076-28317375 FOXG1B chr14: 028317289-028317343 NMI-wt vs Ref
chr14: 33338698-33340189 NPAS3 chr14: 033339869-033339913 NMI-wt vs Ref
chr14: 36122289-36122589 NKX2-8 chr14: 036122225-036122274 MI vs Ref
NKX2-8 chr14: 036123184-036123232 NMI-wt vs Ref
chr14-36205192-36206099 PAX9 chr14: 036196442-036196486 NMI-mt vs Ref
PAX9 chr14: 036205602-036205647 MI vs Ref
PAX9 chr14: 036206112-036206171 NMI-wt vs Ref
chr14: 37137198-37138958 FOXA1 chr14: 037137114-037137159 NMI-wt vs Ref
FOXA1 chr14: 037137543-037137587 NMI-mt vs Ref
chr14: 56347822-56348040 OTX2 chr14: 056347712-056347756 NMI-wt vs Ref
chr14: 60045486-60047933 SIX6 chr14: 060046995-060047041 NMI-wt vs Ref
chr14: 60173732-60174416 SIX1 chr14: 060173710-060173754 NMI-mt vs Ref
SIX1 chr14: 060179528-060179574 NMI-wt vs Ref
chr14: 98781593-98783184 BCL11B chr14: 098782637-098782681 NMI-mt vs Ref
chr15: 50867751-50870991 ONECUT1 chr15: 050870481-050870525 NMI-wt vs Ref
chr15: 58083428-58085812 FOXB1 chr15: 058084349-058084393 NMI-wt vs Ref
chr15: 62984853-62985116 ANKDD1A chr15: 062984784-062984834 NMI-wt vs Ref
chr15: 65902540-65909629 LBXCOR1 chr15: 065908791-065908850 NMI-wt vs Ref
chr15: 72206924-72210097 ISLR2 chr15: 072206870-072206914 NMI-wt vs Ref
chr15: 74414579-74414893 ISL2 chr15: 074414745-074414789 NMI-wt vs Ref
chr15: 88158407-88159577 ANPEP chr15: 088158433-088158477 NMI-wt vs Ref
chr15-94688798-94689131 NR2F2 chr15: 094688839-094688885 NMI-wt vs Ref
NR2F2 chr15: 094688901-094688949 MI vs Ref
NR2F2 chr15: 094689087-094689131 NMI-mt vs Ref
chr16: 727072-727328 NARFL chr16: 000727383-000727427 NMI-wt vs Ref
CBLN1 chr16: 047869472-047869516 NMI-wt vs Ref
chr16-52873104-52882105 IRX3 chr16: 052879704-052879750 NMI-mt vs Ref
IRX3 chr16: 052879918-052879974 NMI-wt vs Ref
IRX3 chr16: 052880382-052880426 MI vs Ref
IRX5 chr16: 053528320-053528364 NMI-wt vs Ref
chr16: 66071900-66072846 ATP6V0D1 chr16: 066071973-066072017 NMI-mt vs MI
chr16-85098883-85102729 FOXF1 chr16: 085098933-085098977 NMI-wt vs Ref
CNTNAP1 chr17: 038089272-038089316 NMI-mt vs Ref
CNTNAP1 chr17: 038089272-038089316 NMI-wt vs Ref
chr17-44074280-44075233 HOXB5 chr17: 044026017-044026069 MI vs Ref
HOXB5 chr17: 044026017-044026069 NMI-wt vs Ref
hsa-mir-196a-1 chr17: 044074404-044074448 NMI-wt vs Ref
hsa-mir-196a-1 chr17: 044074457-044074501 NMI-mt vs Ref
chr17-58865328-58865618 CYB561 chr17: 058865281-058865326 MI vs Ref
CYB561 chr17: 058865281-058865326 NMI-wt vs Ref
CYB561 chr17: 058865512-058865556 NMI-mt vs Ref
chr17: 67627870-67631593 SOX9 chr17: 067630891-067630945 NMI-wt vs Ref
chr17: 71582000-71585125 GALR2 chr17: 071583191-071583235 NMI-mt vs MI
chr17-75531280-75531546 TBC1D16 chr17: 075531439-075531483 NMI-wt vs Ref
chr17: 75936057-75936582 C17orf27 chr17: 075936313-075936368 MI vs Ref
C17orf27 chr17: 075936313-075936368 NMI-wt vs Ref
chr17: 76404186-76404427 KIAA1303 chr17: 076404103-076404162 MI vs Ref
KIAA1303 chr17: 076404103-076404162 NMI-wt vs Ref
chr17: 77537903-77538626 ASPSCR1 chr17: 077538538-077538583 NMI-wt vs Ref
chr18: 894579-899574 ADCYAP1 chr18: 000899042-000899087 NMI-wt vs Ref
chr18-5186244-5187389 ONECUT2 chr18: 053259508-053259552 NMI-mt vs Ref
ONECUT2 chr18: 053259508-053259552 NMI-wt vs Ref
chr18-68359955-68362770 CBLN2 chr18: 068361299-068361343 NMI-wt vs MI
chr18: 74837994-74842232 SALL3 chr18: 074838538-074838582 NMI-wt vs Ref
chr18: 75565313-75565933 CTDP1 chr18: 075565319-075565363 NMI-wt vs Ref
chr19: 898548-898981 ARID3A chr19: 000898650-000898694 NMI-wt vs Ref
chr19-4059891-4060207 MAP2K2 chr19: 004059891-004059935 NMI-wt vs Ref
MAP2K2 chr19: 004060122-004060166 MI vs Ref
MAP2K2 chr19: 004060122-004060166 NMI-mt vs Ref
chr19: 9131907-9132918 ZNF317 chr19: 009132692-009132736 NMI-wt vs Ref
chr19: 12985960-12986259 NFIX chr19: 012986040-012986084 NMI-wt vs Ref
chr19-42586165-42586705 ZNF569 chr19: 042586544-042586592 NMI-wt vs Ref
chr19: 55553586-55553895 NAPSA chr19: 055553837-055553881 NMI-wt vs Ref
chr19: 57082654-57083180 ZNF577 chr19: 057082979-057083023 NMI-wt vs Ref
chr19: 60283718-60285792 EPS8L1 chr19: 060285492-060285536 NMI-mt vs Ref
chr19: 60907042-60907388 EPN1 chr19: 060907107-060907151 NMI-mt vs Ref
EPN1 chr19: 060907320-060907364 NMI-wt vs Ref
chr19: 62043096-62043807 PEG3 chr19: 062043010-062043054 NMI-wt vs Ref
chr19: 63321122-63322053 ZNF329 chr19: 063321824-063321868 NMI-wt vs Ref
chr19-63420090-63420541 ZNF274 chr19: 063420437-063420481 NMI-wt vs Ref
chr19-63784504-63785085 MGC2752 chr19: 063784639-063784683 NMI-wt vs Ref
MGC2752 chr19: 063784804-063784848 MI vs Ref
MGC2752 chr19: 063784804-063784848 NMI-mt vs Ref
chr20: 9444472-9444893 C20orf103 chr20: 009444951-009444998 NMI-wt vs Ref
chr20: 21433933-21444714 NKX2-2 chr20: 021439947-021439991 NMI-wt vs Ref
chr20-22505518-22507240 FOXA2 chr20: 022505822-022505866 NMI-wt vs MI
chr20-22510737-22514165 FOXA2 chr20: 022505888-022505938 NMI-wt vs Ref
chr20-22514762-22515148 FOXA2 chr20: 022507864-022507908 NMI-wt vs NMI-
mt
chr20: 23294035-23294650 GZF1 chr20: 023294489-023294536 NMI-wt vs Ref
chr20: 25011839-25013525 VSX1 chr20: 025011908-025011952 NMI-wt vs Ref
chr20-35582018-35583550 NNAT chr20: 035582918-035582969 NMI-mt vs Ref
NNAT chr20: 035582918-035582969 NMI-wt vs Ref
chr20: 36785545-36790786 SLC32A1 chr20: 036787891-036787941 NMI-wt vs Ref
chr20: 38749965-38753401 MAFB chr20: 038753128-038753174 NMI-mt vs Ref
MAFB chr20: 038753269-038753318 NMI-wt vs Ref
chr20: 49542203-49542863 NFATC2 chr20: 049542266-049542311 NMI-wt vs Ref
chr20-54012011-54014085 CBLN4 chr20: 054013134-054013178 NMI-wt vs Ref
chr20: 54411932-54412178 CSTF1 chr20: 054412143-054412187 NMI-wt vs Ref
chr20: 55680656-55681057 TMEPAI chr20: 055680906-055680952 NMI-wt vs Ref
chr20: 56860125-56860442 GNAS chr20: 056860480-056860524 NMI-wt vs Ref
chr20-60061693-60062033 TAF4 chr20: 060015181-060015225 MI vs Ref
TAF4 chr20: 060062094-060062139 NMI-wt vs Ref
chr20: 62371744-62371958 PCMTD2 chr20: 062371900-062371944 NMI-wt vs Ref
chr21-33316999-33322115 OLIG2 chr21: 033318624-033318681 NMI-wt vs Ref
chr21-36990008-36995832 SIM2 chr21: 036991619-036991663 NMI-wt vs Ref
SIM2 chr21: 036999107-036999151 MI vs Ref
chr21-43350621-43351134 HSF2BP chr21: 043902052-043902096 MI vs Ref
HSF2BP chr21: 043902052-043902096 NMI-mt vs Ref
chr21: 45511336-45511549 POFUT2 chr21: 045511551-045511595 NMI-wt vs Ref
chr21: 46892946-46893236 PRMT2 chr21: 046893181-046893225 NMI-wt vs Ref
chr22: 18453364-18453931 DGCR8 chr22: 018453720-018453764 NMI-wt vs Ref
TABLE 7B
Sequences of differentially labeled CGIs between
bladder cancer subgroups relative to blood
CGI: 561 range = chr1: 63554983-63563059
CGGGCAGGCCCAAGCTGCGATGTGGAGAATTCGATGTCCGAGCGACCTCCTCGGAGGAGTGGGTCGAGTTAAA
TATAACCGCGCGAATGGAATGGCGCTAAAAATAAGGCAGCAGCTGGCCTGTCCACAGCCCTGTCCCGGGAGGG
GCGGGGGCCCCAGTGGTCTTGGGCAGGAAGGCCGCGTCCGGCCCAGGGGCGAGAAGGCTGCGGCGTCCGCAGC
CAGGGCTGGAAGGCCTGGGAGGCCGCGCTCTGTGGGCCCCGGGGCCTCCATTCGGGCTGGGTCGCGGGCCTGG
ACGGGGACTGTCCAGAGGCATCCGAAAGCCAGGCCAACTTGCCTGGACGTAACAAGACGGAAGGGCTGGGCGC
TGAGGTCCTGCCAGCCCGGCCGCCAGAGGGAGCTGAGCGCCAGAGGAGGACAAGCCGAACCCTTCAGGAGGCC
GGGCGTCTCCGGAGACCGAAGCGCCGGAGGACCCGAGGAGGTCTGCCCCGCGCGCTGCTCTGGAGACTCCCGG
GGCGGGTGGCGCTCGGCCTTTCCGCTCCCTTCCTTCCCACAAGTCCCTTCCCGCGCGCGCCCCACGGCCCTGC
CCGCCCTCCCGCGTCAGCGCCCCAACCGTCAAGCCAGCAATTGAAACGTTTCCAAAACGGTCTATTTATTTGC
TCCCAATAAATCGATCGGCGGTGATTAAAGAATCGATGTGGCCTGGGTGGGCGAGTCGCTTGAGGGGAGGGAT
TGGGGGCTTTCGCCCGGCGCCTGCAGGGAGGCCGAGGGCGGGCGCGGGCCTGAGGGAGGCGTGTCCCGCCCGG
GCCACACCCGAGGACCCGACACCTGGGCTGGCAGGCCCCGGCAGGCAGCGTTCCCTCCGGCGGAGAGGGGCGC
GCGCCCGCCGCCTGCTTTCCTCGGCCCCTCTCGCCTTTCTCGCGCGCCGGGGAGGCTGTGGCCGCCAGTGGCT
GCGGAGCTGCTCAGAGGCTTTTGTTGCTCCTCGGCCGGCTGAATGGGGATTTTGTAAAGCGGGACAGATAAAA
ATGAGCAGCATCATATTGTTTGACAGAATGATCTCGCATGATGAAGTGTCGGCTCCGAAGGGGGTGAAAATGG
TGAATTCCTAAAAACCCAGCCCTGGGCTCCTCCTCGAGCTGCCGGTAGCCTGGAGGGACCCAGCGGACAGCCG
GGCCTGGCCGCATCGCTCCAAACGGTGTCAGAAAGACTCCGGCTTTCAATGCCAAGTCATTTTTAAGCCCCGA
TCCTGTCCAGGACCTTTCTCCTCGTGGATGAAAAGAACAATTTTCGAGAGAAAGGCTCGTTTTTATTAAATCC
GACATGCTGCTGATAACTCCATGCTAATGTGAAATAATTAACATAATAGCCATAATTAAAAGCACGCTAACAA
TGCCATAAATTTATCACACAATTTTACTAGCTTTCTGCCCCTAACTGCTCTCTCATCGTTAATTAAACGTGTT
GCCTTTTACAGAATGGATGTTTATATATTTCCAATATAAATAAATTCGAAACCATCCTCTCTCTCTTCCTCTT
TCTCTCCTCCTTTCCTTTTGGTCTCTCGCCATTTACAGGCACGCCTTGGCGTGGACCCTGAGTGGCAGACATC
TTGAAAATAAATGAAGTTTTGAGATGCAAATCCAAACAAGAACATTAAAATAGCCTCTTTTTTTCCACCCCGA
AAAGATCCGGAGAGGTATACAAGGGGGTAGTGGTGGGTAAGAGAGTTGAAAATCCCCCGCTTTGGGAAATGGA
AGTAATCTGGGTGGGTTGGGGCCTTGGGTACCACCTCTGCCCTTTCCCACCTTCCTTGGTGGCGGCCATCCAG
ACAAAGAGGCCGGTAATAGTTTAACAAATCTATGAAGATTTTCAAGAAGCAGCAGACTTTGATTGTTGCGGGC
GCGGGGGTGTTGGGGAGAAAGGAGGGGAATTTTTCTAATAGTCCCACCCACGTTTTGCTCCCTCTTGGACAAA
GAGTAACTACTCTTGGTGGGGGACGCGCCCTTCACTCCGCGGAACCTGGTCCCAACTCCCCGTATTGTAAGAA
AAGTGCACCCGCGCGCGGGCATGATGATTCTATCTCACATCGCGCCAACGACTTATTCAAGCCACTGGCACTG
TCTCTGACTTAAAAGAGGAGAAAAGAGGCATATGGGTTCACTTGGGCCTGGTGAGGGGTAGGTGGGCAATTCC
CGCCTTCCGCACTCTAACCGTGCCCCTCCTCCAGTGTTGACCACCTAAGAACCCAAAATGAGCTGTAATTAAT
TTCCCTTTCTCCATCATAAATTTTTCTATCCATTTCTTCCCCCCCATCCCCCCACTGGACGCACACACTAAAT
CTCCCCTCCCCTGGAGACGTCTCAATTTCCTTCCTATCGATCCGGACTCCATTCTTCTTGCCTCCTGTTGCTA
GAACCTAGATCCCCACTCCCCGCACCCCTCATTCCCACCGCGTCCAGGTGGCTTTCCCAGCGGGGTACCATGT
ACTCTGCCCGCTCCAGAGGAACCGAAGGGGTTTCATTCCATTCTCCTTTGGTTGAAACATTTCAAACATTTGA
GCAGGTGAGGCAGCTGGCTGCCATCTTCCTTTTTAAATCTCTCCTGGGAAGTTCGCTTGTTGAGACTCAAAGA
GTCACTCAAACTCATAATTGCGTGTGTGTGTCTACTCATTCTCCCTCTATCTCTCCAATAACCCTTTGAGACT
CAGAAACTTTTTATCCACATACACCCTTTATCACATTTTCTTCCCCCCACTACATGTGTCTCACTTTCTCTCT
GTATCTGTCTCGCTTCTTCCGTCTCTGTCCTACAGCTTGGCGGTAACTGACGACCTGTGAGCTTTTAGCTGCA
AACTGCAACTACGCGGCAAACAATTTATTTAGCCCGACATCTAGCCGGTCTCCGGCAGGACCCTGCACCGCGT
CGGGATCGGACCCTTCCGCTGGGGCGGCCTCCTGCGTCAAGGCCAGCAGGAACCTTCCTGTCGCCCTCCCCGG
CCGCCGCTTCGCCTCCTTCCCGCCCCCGGAGGTTGTGCAGGCGCTATGGTCCGCCTGGAGGGAGAAAGCCGGC
GGCCGGTTCCTGAGCCGAGAGCGGCCGCGGAAAAATCCTCTGCCTCCGCTGGAAATCGATATTAGGCCGGCGC
GGGCGCGGGACGTCGGGGCCGCAGCCAGTAGGTTGTGCACGTCTCATCATTTAGCTAATCGAGTCGAAAAGTT
TCTGTAAGGGCCGGACCCAGCATCAGATGGTAACACTGATTGAACAAGAGATTAGCACAATAGATCTCTAACC
GAGGGGAAGCGTTGCTTTTCACGCTACGCGCCGTAATTAATGGTATGAATCAATTAATTTGACTTTTATTGTG
TCGAAGGAAAAAAGCGCAACAAATGGAACCGGCAGCTGGGAGTTGTTCGTCCTCCACCCCCTTCCCCAGGGAG
GTTCCAAGGAGACACCGGGGAATGGACGGATCAGGCTGGGCCGTGGCAGAGGGAGGGTAGGAGGCAGCGACCA
GCAGCGTGGAGGGAGTCCAGAGAGCTAGCCTCTGCGGACGGCGGAATCGAAATTAGGCTCATTTGGAGACTAC
TTCGAGACCGGTGAGGGGAGCCCTGTAGCCACCATCCTCCGGCGCGCATCCACACATACTAGTCCACGCGGGC
CCAGCCACCAAGGCCGCGGCAGGGCCAGCGCTGCGCCCCGGGCCCCTGCCTTTAGGGCTGGGCAACCCAAGCA
GAGCAAAGGAGGTTCCTGAATGTGTAAATTTCCGCTTTTTAGCTTTTTTTTTTTTTTTTTTTGGACCTTCCGA
CACTTCGGTTGCTGAGGCAGTTGCAGACGCGACCTCTGCAGTCCTGGGCGATGGCCAGCCAGCTCAGCTCGGG
TCGGTTTCGCGGAAAGCTGTCTAGACGGCATTGTAAACGGTTCGGAGCCTGCGGGCCACAAAGCTGTGGAGCT
ACGGAAATCAACTCTGAGATGCGTTTTAGGGCCGTGTGCAACCTCGGGATCATTTAGATAAAGAAAAACTGTG
GAGGTTGGCGGGCGTCTCAGGATAGTGTCACCACCCCCTACCCTGCTCCCAGCCTCAGATGAGTAGTGTTATA
TCCTGGGAAACTGTCTAATGGGGATGAAAGTCAATCTGTGTGTCTCAATGCCTGTAATGAAGCAAGTTTACAG
ATTTTTAAATTTTTATTTTTATTTTATTGAATTATTTTTGGTGTGTCTAGGCCAAGGAAAGAGGAGATCGTGG
GTGGGGAAACAGACTGAGGGAATCAGAAGCACCACTGTCCATCCGGAATTAAATCCACATCCCAGCATCTTCT
GCAAATATTTCACTAATTATTTCCTCTCGGAACTCCTCCCCTCGTGCTCCTTCCTCTGGTGAGGCCGGCGCTC
CCCTCCCAGGCCGCAGCGGACAGACAGGGATTGGGTTCCGTGTGCCTGCCACACCAGGCAGGCTCTTGCGGCT
CCCAACTAGGCGGCCTAAATGAGGGAGGAAAGAGGAGGCGCATCGCTGATTCACCGCGTCAAGAGCACTGACT
TTCCTTGGAGGTGTGAGGTCCACGCACCCCAGCCACGCACTTGGGGGTCGGTTTGCGGTGCCTCCCCCTCCAG
TCCCAGTGAAATCCCCACAGTTTTTCCTACTATCACTGACTTGCCTTGCACTCCGCGTGCATTGGCCACACAT
CCTCGCCTCCTCCACCCGCTCCGCCGCCGGTTTTCTTGGAAGTTAAATCTTGGAGGATTTGTCCACACCTTAA
GAGAAGAAAATCCACGTTAGCTGGCAGCAACGGAGATCCCAGCATGCTGGCATGCCCAAGTCTGCCCAGGTTC
CCCCAAGGCCATGCCCGCCGCCCGGGAAGTCACTGCCCGCACCCCTCACGTTTCTTCAGCCGCCCCTGGGCGC
TGCGTCTAACCTGAAGACACCAGGCCTCTTCCCGGATCCACTCGACTTACCCAGGCCGCTGCCAATCCCAGCT
CCTTCCCCAGCGCCTCATTTCCGATTTTTTCATATGCTAAGTCGTTTAACAACTCCAAGTAGCCAGTTATGGC
TTCTTTATTTATAGGTTCCCTGCTATTTTACGTCGTTTTTATTTCTCTCGGCAACTATTCTAGTAGATTAATC
AATAGCCATTTTCTGACCTTCGGGAACCCCAGCTGATGCTTTTTGTGGCCGCACGAAAAAATACATACAGGAA
AACACGCCCGCATCAAGCCGGGAAAGAGCAGGTAGGACCTGAGTGGTTTGGTTGGGGGAGGGGGAAAAAGACA
TCTCAGCAGGTGTCTTCCCCGGAATGAGCACTGAGGCCAGAGGGGAATCTGAAATCTAATTAGCAGGAGGGAG
CCGGGTGCGCTGCTCTTACTCTTTAAAGCTAAAAACAATGAAACAAAAAGCAAAACAGAGACTAAGTTTTGCT
TTTTAAAACACGATATGGGAACCTCGTTCTAGGTCGCCCAGTCCCTGTCTAAGGAGTGTGACAAAGTGGGGGG
GAGAAGGGCGGAAGGGAGAGGGGGCGGGGAAGGCAGGGCAGCGACAGTCGCACAGTCCCGCGGACGCTCCCAG
GCCCACGCCCTGACTCGCTCACACCCACCCACACTCACACCCACCCGCTCCCTGGGCCCCAGGGCCCGGATCC
AGCCTGGGTGGGGGGGTCTCCGGGCGGGCCGCAGCGCCCTCCGTGCCCCGGGGATGCTGGCGCACAGTGCGGA
GCGGAGTTGCGCGTCTCTCGTCCCTTTGTTGACAATTCCCTGAACCAACTTGAGTTTGGCCGGCTCGGCCGCG
GCCCTGACGTCACGCACGGTCACGTGGCCCCGCCTCCCGCTGGATCTTTAAGTAGAAAGTAATCTATCAGGCC
AGTCCTTAAAACGGGACTTTCGACTACCGGGGCTTCGGCGTCCCTGACACCCAGCCCCCTGCCCCCCCGCTAC
TGTCCCTGCCCGCGCCCTCCCGAGCTGCTCGGCGCCCGGCGTCCCGCGCCCGCCTGGACCGCTCCTGCGCCCC
ACGCCAGGGCCAGAGGCCGAGGAAGGCGGGCTAAGTGAGGGGGCGCGGCGTGGAGAACCGCCGGGGCCGGGAG
CGGTAGCGAGCGCCTAGTACCGAGCGCCAGGGACGGCAGGAGTTCGCGGAGCGCGGCCGCTGGGGGCGGACGG
CAGAGCCCGCGCCACGCGATGCGGGGCCGCCGAGTGTGAGCTGAGCCCAGCGGGCCCCAAGCCACCTGCGGCC
CCCTCCCCTCTCCCTGCCCCCCATCTTTCGGGGGCACTCAAACCCTCTTCCCCTGAGCTCCGTGGCAGCCCCC
GAACACCCTCATCGCCCGCTGCCCCCTCCCCGCCGCCGCTACCAACCCCGAGGAGGGATGACCCTCTCCGGCG
GCGGCAGCGCCAGCGACATGTCCGGCCAGACGGTGCTGACGGCCGAGGACGTGGACATCGATGTGGTGGGCGA
GGGCGACGACGGGCTGGAAGAGAAGGACAGCGACGCAGGTTGCGATAGCCCCGCGGGGCCGCCGGAGCTGCGC
CTGGACGAGGCGGACGAGGTGCCCCCGGCGGCACCCCATCACGGACAGCCTCAGCCGCCCCACCAGCAGCCCC
TGACATTGCCCAAGGAGGCGGCCGGAGCCGGGGCCGGACCGGGGGGCGACGTGGGCGCGCCGGAGGCGGACGG
CTGCAAGGGCGGTGTTGGCGGCGAGGAGGGCGGCGCGAGCGGCGGCGGGCCTGGCGCGGGCAGCGGTTCGGCG
GGAGGCCTGGCCCCGAGCAAGCCCAAGAACAGCCTAGTGAAGCCGCCTTACTCGTACATCGCGCTCATCACCA
TGGCCATCCTGCAGAGCCCGCAGAAGAAGCTGACCCTGAGCGGCATCTGCGAGTTCATCAGCAACCGCTTCCC
CTACTACAGGGAGAAGTTCCCCGCCTGGCAGAACAGCATCCGCCACAACCTCTCACTCAACGACTGCTTCGTC
AAGATCCCCCGCGAGCCGGGCAACCCGGGCAAGGGCAACTACTGGACCCTGGACCCGCAGTCCGAGGACATGT
TCGACAACGGCAGCTTCCTGCGGCGCCGGAAACGCTTCAAGCGCCACCAGCAGGAGCACCTGCGCGAGCAGAC
GGCGCTCATGATGCAGAGCTTCGGCGCTTACAGCCTGGCGGCGGCGGCCGGCGCCGCGGGACCCTACGGCCGC
CCCTACGGCCTGCACCCTGCGGCGGCGGCCGGTGCCTATTCGCACCCGGCAGCGGCGGCGGCCGCGGCTGCTG
CGGCGGCGCTCCAGTACCCGTACGCGCTGCCGCCGGTGGCACCGGTGCTGCCTCCCGCTGTGCCGCTGCTGCC
CTCGGGCGAGCTGGGCCGCAAAGCGGCCGCCTTCGGCTCACAGCTCGGCCCGGGCCTGCAGCTGCAGCTCAAT
AGCCTGGGCGCCGCCGCGGCCGCTGCGGGCACAGCGGGCGCCGCGGGCACCACCGCGTCGCTCATCAAGTCCG
AGCCAAGCGCGCGGCCGTCGTTCAGCATCGAGAACATCATAGGTGGGGGCCCCGCGGCTCCTGGGGGCTCGGC
GGTGGGCGCTGGGGTCGCCGGCGGCACTGGGGGTTCAGGGGGCGGCAGCACGGCGCAGTCGTTTCTGCGGCCA
CCCGGGACCGTGCAGTCGGCAGCGCTCATGGCCACCCACCAACCGCTGTCGCTGAGCCGGACGACTGCCACCA
TCGCGCCCATTCTTAGCGTGCCACTCTCCGGACAGTTTCTGCAGCCCGCAGCCTCGGCCGCCGCCGCTGCTGC
GGCCGCCGCTCAAGCCAAATGGCCGGCGCAATAGGGACGCGCCAATGGCCGGGACCCAGGGTCCGGCGGCGGC
CTCGAGCAACAAATGCACCTCCAGGCTGCGCGCCCTGTCCCAAGCCCGGTCCCGGTCCCGCTGCCCAATCCTG
GACTCTGCCTCTCCCCAATTTCCTTTCCCCTGAGCCCCCAACGCCTACCTTCCGCGGCCTCCATCCCCTCGCG
CACACCTAAGCTGGTCGAGCAAACTCACCGCGCGCCCGCCGGGGATAGCTTTCCATACAGGTAAAACCGAAAA
CCGAATTTTCCAAAAATGCACCCCGACGGCGCCTGCTCTTAGTACCG
CGI: 26 range = chr1: 90955098-90955445
CGCGTCTGCTACCAGATGCGGCTCCGGGGGCTCCATGGTGACTGAGATAGGAGAAGAAGGCGCCGTCCCTACG
GTATCAATCTCCGAACAGGGAGATGGGGTGGCCTGACTCCTAAAATCCGCGGTCCTGGCCTCACCGAGCGGGC
GGAAATCTCCATTCATCATGCCTGGGCTGCCTGAACTGGCACTGGACAAAATCGTGTCTATTCCAAAACTCGA
CCCGCTGGCCCCTTCCATTGTCATTGCTACATGAGGTCCACGCCACTCCGCCGTTCAGCAGCCGCCCCGAACC
AGCGAAGAAAGCTATCGATCGTAAAACAAAATAAACACCAAACAATGTTGCCGCCG
CGI: 29 range = chr1: 163590111-163590435
CGAGAGGCCCGGCCACCGGCTCGGGAGCTGGGCCGGTCGCTTTGGGAGCGGATGAGGAAGGTTAGGAGAAGCA
GCGAGATAGATCCCAATTTTACAATTCTATTTTCTTTCGGTAGGGTCTCGGCGTCCTGGGCCACGTTGAGAGC
GAACGTGGGCCGAGCGGAGGACACAGAGTAAAAAGCGACGCCCGCTGTATACATAAATCCGCACCCGCTGCCC
GCCCGGGTACTGCCTGCTCTGGCTTCCGCTCTCTTCCGAGGCTGGGCAAGTCCAAAAGTTCCCGAAAGGGGGG
TTCAAAGAGGGGCGCTCAGTGCACGTGATTTCG
CGI: 32 range = chr1: 173258989-173259419
CGCGGAAGAGGGCGGAAGGAGAACCCCTGGACTGGTCCTCACCGAGCACTACAGGTGGCAGAGCCGTGGGGGA
CCCGTGGGTTATGAGATTCAGCGGTGAGGGGTAGCGGTGTGGATAAAAGTAGAGGCCTGACCTGCTTGAACGT
CCGCAGCAGCGAGCCCAGCATGAAGGCCGCCATGTTGTCCGCTACAAACTACAAACCGCTGAAACTTTATTGA
CACTGCCGAATAGCGCAGGACACGAGGGGCGGGGCCTGGGCCGCCTGGGGCGGAGCTGGGAGGTGGGTGGGAA
TGTGGCCTACAGGAAAGCGGGGTTAGTTTTGGGATCGGAGCTCTCGCGATATTTCACGGAACTTGGGCAAATG
ACAAATCTGAAGGCGCCGCGTTGATGCTGATGGCGCAGCCAGACCCGCCCCGTGTGTTGCAGCCCG
CGI: 58 range = chr1: 196153712-196154414
CGTCTGGCCAAAGGCGCCCAGCTCAACGGCCGCGACGCGGTAAGGAAGGGCTCCGCCGCGGCGGTAGCCGGGC
ACCCCTGCGCCCTCTGTTAAACCAAGCCGACTCCCTGGCCGGTGGAGAACCGGAGCGGCGGGTCGTAGAGACG
TCCGCTTGAGGGTGGCGGGTGAGTTTTCTCCCGTCCACCTATGCCTACAGGGCTAAGAAACGGTCGTTTTTCT
GAATCGAAATGTCTGCAGCTGGCTATCCTCCGTCGCAGCTGATTCCGAAAGAGCAGGGAGAGGAACTGGGAGG
AGGTGGGATGGGGGGTGGTGGCATTCTCTTCTACAGACCTCAAGGTTCCCTTGATTCCGGGGCAGGCGTCTCC
CCGGCGAGGATCCGCAGCTCCGAGGGCAAGCTGGGCATAAGCAATAGGAGGACGGCGCGCTGCCGAGGCGTCC
GAGCCAAGCAGGAGCCCAGGTGGCCTTAGTCTCTGGGCCTGATGACCGGACCTGTGGAGTAGATTCCGACGCG
ACTGGGTCATTTCCAGTTCTCTAGACGCTCGGGGCTTGGGACCCCTAACCGAGAGAATCTCAGGGTTTCTGGC
ATCCCGACTCAGTCCCTCTAAGGAGACAGCACTACGTTTAGCGCCAGGACCCGGCGGGTGTCATGTGTAGGGG
GAAATCAAATAAAACATACGGAGGAGCGCGGCACCCAGTCGAAACG
CGI: 43 range = chr1: 219117072-219117487
CGGCGGGGGTCGCTCCAAAGACTTGTATTTCGCGTTTGCCTCCGGGAGCTGGGAGTAAGGCCTTGGATGGCGC
CGACGCGGTTGCGAGGAAGCTGAGGCCTGGGAGAGCAAGGGGCGCGCAGGCGAAGTTGCAACTTGCACTCCAG
CCGCGGGCCTGGCGGAGAAAGGGAGGCTCGCGGCGCCGCGAGGAGTCGGCGGGCCTCGGGGCCTCGCTTTCGC
CGCATCTGCCCAGCGCTCCGGGCCTTGAATCTCGGCAGATGCGAGTTGTGGGCACCTAGGGAACCCTGAGGAC
TCGCATTCCCCCGGGTCTGTATCCCGTGCCCACCCCGGAGCGTCGCAAACCTTGGAAAGGGTGAAAGCTGATA
GGGGAGTCTTATTTCTTAAGAGAGAGGGTGAGGGCGCGCGGCGCTGCCTCG
CGI: 25 range = chr1: 241719037-241719368
CGGAAGAGGTGGACCGGCTGCGGACCCAGGTACTGTGCAGAACGCGGCGCAGGTGGGAGTCCTTGGGCGGGCG
TCTACAGGTGGATCTTTTATGCACCTCAACAGGCCGGCTTTCTCACGGATCACATCGGTTAGCAGTAAGCTGG
GAGGGAGGTCCCGAAGACTGTGCTGGGCACAGTGCAGGACCCAGAGAAGCGGAGCCATGGGCCCGTCCTGGTG
AGGGAGTTAAAGTCCGTGCAGGTGAACAGACCCCGGCCCGCGAATCAACGAACCACACCGAGTGCCAAGTTGC
GCCGTGCAGGCTGCGGAGGGTGCGAGAGCAGGGAGAAGCG
CGI: 132 range = chr2: 54536404-54537878
CGAACGCAACATCAAGGGCGAAAAGAGGCTGCACAAATCACGTAGAAAATTAGACCGCCTCTTTCCATGGCGA
TAATCGAATTAGCCTCAAATTAAACGTGAAATTGGCCCTCTCCGGCTGTGGAGACAAAGCCCCTATTGTCCTG
CTCGGGTAGCGGCAGCAGCAGTGCCCACCCCGCCCCGGCCAGCCTGGTCGGTCCCCGCCGCTGGGAGGATGAG
GTCCGGGCTGGACCCGGGAAGAGCCTCAGCTGGAGAGGACGTGGACGCGCCCGAGGCTCGGCTCCCTGGGCGG
CTGCGGGGCTCCGGGCAGGAGGAGAGGGCGGGCGAAGCAGAGGGAGCGGGCGGGAGTGGGGAGGGAGGAGTGC
GGAGGGCGGAGGGCGTGCGGGAGGGATCCCGGGAGTGCGCTTGTGTGTGTGTGCGCGCGCGCCCGCCCCGCGC
GCTCCTCTCCCCGCCCCTCGCCCCCTCCCTGCGAGCGCCCTCCTCTCCTCCTCCCCCCGCCCCCCGCGCTCCC
GCCCAGCCCCCGGAATCAGTGCCGCTGTTGCCGTGCAGGCTGCGGATTCCTCCAGTCCCTCCCTCGGCCGCCT
CTCCTCCCGGAGCGAGCGCGCAGCCCTGCGCAGCAGCGCCCACTGGTCCCGTCCTGTGAGCCCCGGCCCCAGC
CGCGGACAGACCCGCGGAGTCGCCTCCCGGCCCACCCGCCCGGCCGCCGAGGAGCGGGAGGAGGACGGGACCC
CGGCGCCCCCACCCCATCCCCGGGAGGTAGGTAGGGGGCCCGAGGCAGGGAGATGCCAACTCACTGGGGCTGC
CTCCCGGGTGGGCTCCGCGGCGGCGGACGGGCGGGAGGAGGGGCGCGGGCCCAGGGCCGGAGGACGCCGCTGC
CCGCCTGCCCTGCGCCCGGGGAGCCGCGTGGGGGCAGGGAGGCTGCAAAGCCCGGGCGGGGGCGGCGCGGGGA
GCCCGGGTCGCGGGTGCTCATTGGTACTCGGATGATGCGGGACGAGGGGCGGCAGGCTCTGCGGTGAGGCGGC
AGCAGACCCGCCGTGCGCACCGCTGCCGTCCGGCCCCAGCCCCGGCGCGGCGCGGCGATTCCTCCTCCCTGCC
TCCGCCGGCGCCTCCCTGCAGCCGGGCGCGGCGGCCCCTGACGCGGAGGCCCCTGGCGCGGAGGTGGGTGCGG
AGCGGACAGCGGACAGCCGGAGGGTCTATTTTCAGGTGCCCTCTCTGTGGCCCCGCGGGTGGGGAGCGGGGGC
GGCGGTGACAGGGCCGGGCTCTGCGCGTAGCGGTGCAGGGGATGCGGCCAGGCGTGGTCCCGGCTGCGCCGCG
CTGCAGCTGAGCCGGAGGCGGCGGCCCCGCGCCCCCACCTCCGCCCCATCCCTGCGCTTGCTACCCTCGTGCG
CCCGCCCCCCCCCCGCCCTTTCTGCCGTCCCCACTCTCCCAGGGCTGGGCGTGAGCCGCCTCCGGGCGCCGAG
CCGCCGCTGCGCCCG
CGI: 77 range = chr2: 73004709-73005568
CGCGTTCCCCCGCGGAGTGGCTCTCGAGTGCGGGGAGGTGTTGCGGAGGGGAGTGGACTTAGGGAAGGGGCGG
CAAAAGGGCAAAGGGAGAAATGGCGTGTGTGTGCGTGTCAAGGAATGGAGAGGGCAGGGCGCTTGGGAGCAGG
GCGCGAGGCCAGGCTCTGTTGGGCCCCGGCTCACGGCGCCCCTTCTCTCTGTCTGTACCTGCGTGTGTTGCCG
TCGGCGGCGGGGCCGCAGCCAGCGACGTGCCCCAGGACGGGCTGCTTCTGCACGGCCCCTTCGCACGCAAGCC
CAAGCGGATCCGCACGGCCTTCTCGCCCTCGCAGCTGCTGCGGCTGGAGCGCGCCTTCGAGAAGAACCACTAC
GTGGTGGGCGCCGAGCGGAAGCAGCTGGCCGGCAGTCTCAGCCTCTCCGAGACGCAGGTAATCACCCCCGGTC
GCGGCCTGCCCTGCGCCCGGAGCCCGGGTGGAGGTGAGGGTGCGCGGGTGCAGGAGAGGCCCTGAGCCCGCCC
CAGCCCAGCCCTGCTGGGTTCCAAAAGGCCCCCATTCCCCGCGGCGCTGCGGTCAAGCCCGTCTTTAGAGCCT
CTTCCTCGAGACTGCGTGCAGCCTGCTGAGCCCGCAGGACTTTTGTCAAGCGCTAAAGACCTAGCAGGAGGCA
GAGTAAATGCAAACTGTATCCCGAGCCCGGCTCCCAAAGCTCCTCACGGGGGGACCAGGTTCCCTGGAGGAAG
CGGGTCGCCTCGGGAGCGGGCAGCGCAGGCAGCACCGAGGCCACTGGAGCTGGCTCCAGCCCTGGCATTCCTG
CAGCCCTTTTCCCGCCACTGTGTCGGGGCGCTCATAGTCCTGCGGGGAGCCGGTCCG
CGI: 221 range = chr2: 85213468-85216104
CGGGGGTCGCGTTGGAACCCCACAGGAAAAAGGCGCGGAAAGCCGCCGGGCATTTTCCGGGGTTCCATAGATG
TCCCCAGTGTCCTAGTCCGTGCATCAGCTCGCGCACTCGGAGGGACTCTAGGCAGGGGGAGGGCCCCGCGGCC
AGTATGTGCGTCCGAGGCTTTCCCGCAGGGGGCAGTGCCGCCCGCCCGCGCGCCGATACGGTGGGAGGGGGTG
GGAACCTGCGCGGAGTTCTGGAGGTTCTTTGGGAGAAAGTTAGGGGATGCGGAGGGGTGGGCGCAAGACTTCC
AGGACTCCAGGGAGGCCGTGGGGAGGGCCGCCGAGGGTGCAGTGTGAGGCGCAGGAGGGGGTTGGGGGCGGTG
CACGTTGCAGGGAGACGCAGCCCCTGGAAGATGCGAGTGTGAACGTGTGAGTGTGAGTGCGTGTGTATGTGTG
TGTGTGCGCGCGCACCGCAGCTCTCCGGGTTCCGCGAGGCGCGCGGGTGTCAGCTTGCAGCCGGGGCTCCTCC
CTCCGGCCCCCCTGCCCAGCCCGGCGGTCCCTCCTCCCTCCCTCCCCGCTCGCCCCTCCCCGGCGGGCCAGGG
GCTGGGACGCCCCGGCGGAGCAGGCGGCGGCGGTGGCGAGTTGGGGAGCCCTAGGCTCGGCGCTGCCGGAGGG
GCCCGAGCCGAGCCGCCTGCGCCCCGGCCGGGCAGCGCCGGGCCCGCTTCCCGCGGGGCCACGCCCTGTCAAA
CTTTGTTGCGGCGGCTAGCGCAGCGGGCCCGCAAGCGGGCGGGAGGGGCGCCGGGCCGGGCCGGGCAGGGCGC
GGGCGGCTAGGGGCTCCGAGAGCGGCGGCCCCGGCCCGCGGCCCCACCATGCCCCAGCTCGGCGGCGGGGGCG
GCGGCGGCGGCGGCGGCAGCGGGGGAGGCGGCGGCTCCAGCGCCGGGGCGGCCGGCGGAGGGGACGACCTCGG
GGCGAACGACGAGCTGATCCCCTTCCAGGACGAGGGGGGCGAGGAGCAGGAGCCGAGCAGCGATAGCGCCTCG
GCGCAGCGGGACCTAGACGAGGTCAAGTCGTCCCTGGTCAACGAGTCGGAGAACCAGAGCAGCAGCTCGGACT
CGGAGGTAAGGAAGCACCGCGGCCACCCCCGGGGGATCCCGGCCCTGCGTCCGCTCACCCGCTCTTGCCTTTG
TGTCTCCTCCGCAGGCGGAGAGGCGCCCGCAGCCCGTCCGGGACACTTTCCAGAAGCCGCGGGACTATTTCGC
CGAAGGTATGTGCCCGCTGGGACAGCCCCCCACTCTCGATTCCCGCTGCGCTCCGCTGCTCAGCCCGGGCGGC
CCACCGTCCCCCTTGCTTGGGTGGACGCACCCTTGCCCTCCGCCTTTATTGGCGGCAGCCCCCGTGGGGCGCG
CGTGGGGGGCGCTGGGGTCCCCAGCTCCCGCCTCGAGCCCCCTGCCGCGGCGCTGTCAGTCCCGGGGGCCTGG
GCCTCACCTCGCCTTGGTCTTGTTCGCAGTGAGAAGGCCTCAGGACAGCGCGTTCTTTAAAGGACCCCCGTAC
CCTGGGTACCCCTTCCTGATGATCCCGGACCTGAGCAGCCCGTACCTCTCCAACGGACCCCTGTCTCCCGGAG
GAGCGCGCACCGTGAGTGCCCGTCGGGCGCGCCGGGGAGGGTGGGAGGCCGCGGCCCGCAGGATGCGCCCCCG
GGCTTGGCCATGGAGTGGGGGATGGGGCCTTCTGCGCCGATCCCAAGCAGAACTTGTTTGCGGAGTTGAACTA
CTCTCTGGCGGCCGAGCGCGAGGCTGCGCTGGCCAGTGCCTGGATGAAAGTAAAGTTACTTTAACTTTTCCCC
TCTTGCGGGTTGAGGTTTTGGAGTCCACCTCTGGGATCTTCCTTGGCCTCCAGAATTCTTCGCCTGCACCGAA
GGAAACTTGGATTTGTGCCCGCTTTGGGGGGGTCTCGCTTTCCTTCTTGGAAATCGGTCAGCTTTCTCTGGCA
GTGGGGCAAGGGGCCTAGGGAGCTGGGTTGGCGACGTTGTCCTCCGACTCCGGGTTCACTGGGCGGCTGCAGG
CTGGTTCCTAAGAAACCCAGTTTTCGTGGCGGGTTATTCACAGCCCCCGTTCCCACCCCCAGCCCTCGCACCG
GGGCCTCAGCTTTTCTGCGGAGCTAGCTCCGAATTTTAAACTCGCGTAGATGATTTCGAGGCGACCCAAGGCA
TTCTTCAAGTTGAGGAACTTGGCTTTTTCCCCCTTTTGTCGCCTGCTTTTCTCATTTAAAGCGAGCGCTGCGA
CACTTTAAACCTGTTAATGGGCGCGTATTGTGTGCTGCCCGCTGGCATTTAGAGCGGTGATTAAGCAAATTGA
CCGGGCCCCAGACGACGTGCAAATGAGGGCGGATTCCTTCGCCCCCTCTCTCTGGCTCTAAACTCCCGCCCCC
CGCGTTGCGAGGGGCGCAGCTGGGGGCTGGCGAGGCCTTTGTGTCCCCCAAGCCGCCACTCCACCCCTAGGCT
CCCTGCCCAGGTGCTGGGTCCGATGACAGATGTTGGGTGAACGCCTACCTACTGTGTGCCAGGTTCCCGCGTG
CTGCTGCTTGGGCGCGATGTGAATCGTAGTAGTTCTTTGCTTCCCGCCCAGATTCCCATTGCCTGCCACTTCG
CTGTCGACG
CGI: 173 range = chr2: 119329502-119332035
CGAGGAGGCTGCAGGGACGCGCATGGAAGAGCCGGTGCGTGGGAGGGTTTGCGGGGGGGACATCGCGCCCCCT
AGGGGTGACCCCAGTGGGTCCCGTGTGCTCTCCGCGGAGCCGGCGGAGCCTTGTCCTCTGCACCCGGCGCGCA
GCGGCCCCTTAAACAGTGGAACCGTGAGGCCGCTCTAAGCCGAAGGGCTGGAATCTGGGTTTCTCGGGTTTTA
TTTTAGACCATTCGGCACCAAGCCCGAGCTCCCCCGCCGCACCGCTTCCAGTCCCCTTTCTTTCCATAGAGCG
ACCCGAAGCCGGCGGTGGCGCAGGGAGCCGAGTCTGATGAGCTCGCGGGCGGCTGAAGGCCGGCTTCCCTGTG
GGGAACGCGCCACCTGTCGGCGCCAGTGAGAACTGCGTCTGTGTGGCGCCCTCGGGGTATTCGGGGCTGCGGG
GAGATGTGTGCCTGAAGCCCTGCGCTTGCGGTGGGGACGTCCGGCCTCTTTCCTGGCAATTGACCCCTGAGGC
GGGAGAGACAACGGAATTCCCACAAAGGGATCCTTCTCGGGATCTCCCCACCTCAAGACAGCTAAAGCTGGAG
GAAAAGCCCCTCCGGGGGGTGGGGGGTGCGGGTTTGCCCTGCGATTCCGAAAGCAGAAAATACCCGAGCCACA
CAGGGACGGGCGCCGCGTTGGTAGTCGGGGCTACGTTCCTACTCCCTCTACCTCCCCCGCGCTGTGTGACCCT
GGGCGGAACCCCGCTGCTCTCTGGGCCTCAGTGTTCTTATTCGTAAACTGAGGGCGTTGGATGAGATTGGTCC
TCTCCCAACTCTGACCTTGAAACTGATACTGAATCTGAGCAGCGTCTGTAGACACCTGTGCCTTGCCTTCTAT
TTCTAGCCTTGAATAAATCCTGGACTTTTATGTGCCATTTATATCCTAATCTCATATATATTTAATGTATAAC
TGCTGCCATTATTGTTTTCTCAATTGTCTAGGTTTTCATTTGGATGGGGTTAGGATGGTCCAAATTATCCCGA
TAAGTGCCCATTAACTTAAACCTTTTTAAAAAATGAAACCAGTAAAACTTCATTCACTTTGCAGTGTGGACAC
TGCTGGAGAGCACCCATGTCGTGGGTCCAGCGAGGACACAAGGAGGGGCTTAGAGACATGCGGGAGGCTTAGA
TGAGAAGACAGCACCCGGGCAGCGGTCAGTGTTAGAGAGAGGACCCGTAAGAAGGGCCGAGGCTAGAGGGAGA
GCGAAGACTGAGCCAACGACGCACCTGAGCCCTGGGGTGGGGGTGGAGACGTGGCTCCTAACCCAAATCTCCC
TGCCAGGCAGTGTCCGACGAGCATCGACGGCAGGCGTCGAGACCAGTGCAGGGTAGCTCAGACCTCAAGCCAC
GCTTGACCTTTCCATGAAATGAATAAAACTCGAAAGCCAGGGAAAGGGGACAGTACTTTGATCCGGAGATCGC
TTATAACCTCTGCTTGGAGTTCCGAGTTCGTGCGGCTCAAGGGAGGCTACAGTCCAGCAAGCTCTGGGCTCCA
AGCGTGGGGACGGCAGCCCCCAAGCTTGGCGCACCCCTCGGGAAGCCCCGGAACGGTCCTCGCCAGACATAGC
CGGCTGTCCTGGTCCTTAGCTTCAGGCTGGCGGCGCAAGGCCAGAGCGGCTGCCTTCTAGGCACCTGGGTGGA
GGTCTCGCATAGCATTCCCTGAGAAGCGAAACTGCCCTTGGGGCCGCAGCGAGCCTGCCACATCGAACTGGAG
ACCCTCTGCTTTCGGGATAGATGGGACGTTTCTGCTCTGTCCTTCTTGGAGTCCCGGAATCGTTCTGGGGCCG
CGTGCTGCCTGGAGGCGGTGAATTTCAGGGTCTTGAGAAGCCGCGCACACACGGGATTCTGGGCGAGCGTCCC
GTCTCTTAATTCCTATTAAGAGACGGGAAAATCGAGGGACTGGAGGTCCCATCATTGTCGCGTGAGCAGCCTC
CTGAACACCAAGCGAGACCTGAGGGTTCCGCTGGGGCCTCGCCCTGACACCCGGGCCCTCCGTGTGGTCGAGA
GTTTGCGCCCGCTCCCGCTAGGGCAGCGAGGTCCCACTTGCGGCCGGCTGGGGCATGGTGGCACCGGTTGTCT
ACTCCCCACTTGTGACACCGACAGCTTCCAACTCCTCAGACCCACCCCGTGGAATTCTGGACTTTGTGAGGGC
CGCCGGGGTCCTGGCCCTGGGGTCAGCTGCCATCTGACTAAGCCAGGACGGCGGAGCTCCAGGCCTTGCTCCA
GCACTGCCGGTGCGTCGGGGCCCGCGGAGAGCCCAGGGCGGGAGCTGTGGGCTGAGCCGGGTGGCCGCGTGGA
CACAGATGCCCGGCCGGACTGAGCGGCAGCCAAGACTCTCCGTCCATCCCGCCGCTGGACTCGACTCTCCCAG
ACCCGCCACGGAACCCAGATTTGAGCACGCAAGATAAAGACGCCAGAGGCGAGTGCGCGGCGGAGAACTGGCC
GCGACACGGGAAGCTTCTGGGGCGCAGAACGCTGGCTCCGACTCGCGCGGCG
CGI: 36 range = chr2: 172653235-172653630
CGACGGCGCGCTTGTGGCCCGGCCGGAGCTTGCGTGCGCGTTCTGACGGCTGGGTGCTGTGTTACAGGTCGGC
GCAGTTCGAGCACACGGTTCTGATCACGTCGAGGGGCGCGCAGATCCTGACCAAACTACCCCATGAGGCCTGA
GGAGCCGCCCGAAGGTCGCGGTGACCTGGTGCCTTTTTAAATAAATTGCTGAAATTTGGCTGGAGAACTTTTA
GAAGAAACAGGGAAATGACCGGTGGTGCGGTAACCTGCGTGGCTCCTGATAGCGTTTGGAAGAACGCGGGGGA
GACTGAAGAGCAACTGGGAACTCGGATCTGAAGCCCTGCTGGGGTCGCGCGGCTTTGGAAAAACAAATCCTGG
CCCTGGACTCGGTTTCCCAGCGCGGTCAACG
CGI: 295 range = chr2: 174907710-174910885
CGCCCTCGCCCCCCCCCCGCAAGTATCCCCCACTACTCCCCCCCACCCCCGCGGCCCTAGCTAGCTGACTTGA
CTGGCACGCGCCGGGAGCCCGGGCTCGGGCCCCTCGGAGCGTCTGATTGGCTGCGGGGCAGCTCCGGTCTGCT
CTGCCTGCGCCCTCATTGGGCGAGAGGCGCAGCCAGCGGCACTTCAAAGCGGGTGCTCCTCGCACTTAGGCTG
AGTTTAGCCGGCGGGAGCCTGGAGTCCGCTCGGCACGAGCGCGGGGACGCGGGAGCCGCGCGGGACCCAAGCA
GTTTTTCCGAGCAGCCGCCAGGCTCAGCCCCGCTCCCAGCCTCGCTGCGCAGCCAGAGACCTGCTATGGCCAC
GTCTATACTCGGGGTAAGTCGCAAGCGCGGCAACGCATTTGCTTGTTTTAACCGGAGTAATTTTTCGTTATGG
CTTCTGGGGTCTGCGGCTCCGGAGAAACTGTTGCTGCTAGACTGCAGCTTCAGCTTCTATTAGCACTTTCCAC
ATTTCTGGGACTGATTTTTCCCCAAGTTTTTGGAACCCAGAAAGATGCCTTTGCAAGAAAAGGCCTTCTTAAT
CAAGTCCTTTTTCATTTGGTTTCAAAAAAAAGCTAGAGGTTTCTTTTCTTCCCCTCGTGATTTATACCCCATC
CCCCGCATTGCTTTGGGGATTTTGTTGCAATTATGCGACAATGGTGTTTCCAGAAAACAGTCTTAATCGTTTT
GCAGTCCATCTAGTCACGCTAATAAACATTTACATTTCCGCGGCTCCCCAATTCGCCCATGACTTTGAAATCT
GTCTCTGGCCGCTTATCCTCGGATTATTGTTTTCATAATCGCTGTTTTTGTGTGTATGTAAACTTTAAAACCA
AACGTTTTCTATTAAAAAAGAAAAGTCAAGTCGTAGCCACCCTGGGAGAGCTGCAAGTTTCGCCCGTCCCTGG
CAGCTGTTTCGGCCGCCTCCGCCCTCACCCGGTGTTTGTTGTCTCTGGTCTCTGTGTTTACCTTCGCGCTTCA
CCCCGAAGGGCGACTTGGGGTCTTCTGGGAGATGAGCCGGTTTACGGCGACAACCCAAGTCCGGTTGTAGGCA
GGGTTGCAGCGGGGAACACGGAGGCATCTTTGATTTATAGCCTCAGCGAAGTGCAACTTTCCGGCGCCTGGAC
CTTCGCCCGGGTGATCGCCCCTGCTCCGCGCCCGGTGCGGCGACTCCTCCGCGGGCGCGTGGGGAGGAGGCGC
GAGGCGGGGAGCCAGGACCCCCCGGGAGCAGCCGCAGGGGACGAGGCTGCTCACGGGTGCACTTTGTTTCTTC
CCCCACTTCCTCTTGCCCTCCTCCTTCTTGCTCCCTCCCCCATCCCACCCACTCTAGGAAGAGCCGCGCTTCG
GAACGACCCCGTTGGCCATGCTGGCGGCGACCTGCAACAAGATCGGCAACACGAGCCCGCTGACGACGCTGCC
AGAGTCGAGCGCCTTCGCCAAAGGCGGCTTTCACCCCTGGAAGCGCTCCTCGTCCAGCTGCAACCTCGGCTCC
AGCCTCTCGGGCTTCGCGGTGGCCACCGGGGGCCGTGGCTCGGGCGGCCTGGCGGGCGGCTCGGGCGCCGCCA
ACAGCGCCTTCTGCCTGGCCTCCACGTCGCCCACGTCGTCCGCCTTCAGCAGCGACTACGGCGGCCTCTTCTC
CAACTCGGCGGCTGCCGCGGCGGCAGCGGCCGGGGTGTCCCCGCAGGAGGCGGGTGGCCAGTCGGCCTTCATT
TCCAAGGTGCACACGACGGCAGCCGACGGGCTGTACCCGCGCGTGGGCATGGCGCACCCGTACGAGTCCTGGT
ACAAGTCGGGCTTCCATTCGACGCTGGCGGCCGGCGAGGTGACCAACGGCGCGGCGTCGTCGTGGTGGGACGT
GCACAGCAGCCCGGGCTCGTGGCTGGAAGTGCAGAACCCCGCTGGGGGGCTCCAGAGCTCGCTGCACTCGGGC
GCCCCCCAGGCCTCGCTGCACTCGCAGCTGGGCACCTACAACCCCGACTTCAGCTCGCTCACGCACTCCGCCT
TCAGCTCCACGGGCCTCGGCTCCTCCGCCGCCGCCGCCTCCCACCTGCTCTCCACCAGCCAGCACCTGCTGGC
CCAGGACGGCTTCAAGCCGGTGTTGCCCTCCTATTCGGACTCCAGCGCCGCCGTGGCAGCCGCCGCCGCCAGC
GCCATGATATCGGGCGCCGCGGCTGCCGCCGCCGGGGGGAGCTCGGCACGCTCTGCCCGCCGCTACTCGGGCC
GCGCCACCTGCGACTGCCCCAACTGCCAGGAGGCGGAGCGGCTGGGCCCGGCCGGGGCGAGCCTGCGGCGCAA
GGGCCTGCACAGCTGCCACATTCCGGGCTGCGGCAAGGTGTACGGGAAGACGTCGCACCTGAAGGCGCACCTG
CGCTGGCACACGGGCGAGCGGCCCTTCGTGTGCAACTGGCTCTTCTGCGGCAAGCGCTTCACGCGCTCGGACG
AGCTGCAGCGGCATCTGCGGACTCACACGGGCGAGAAGCGCTTCGCCTGTCCGGTGTGCAACAAGCGCTTCAT
GCGCAGCGACCACCTGAGCAAACACATTAAGACGCACAACGGGGGCGGCGGGGGCAAAAAGGGCAGCGACAGT
GACACGGACGCCAGCAACCTGGAGACGCCCCGTTCCGAATCCCCCGACCTCATCCTGCATGACTCCGGCGTCA
GTGCCGCCCGGGCGGCGGCAGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGCGGCCTCCGCGGGAGGCAA
GGAAGCAGCGTCTGGCCCCAACGACTCTTAGAGGCCGGGCGAGAGGCGCGAGCACACAAGCGAGTAGAGACAC
CGAGAACGAACGAGAGGTTCGGAGGGCGAGCGAGCGGGAGGCGGGAGGGCAGGGGCTTCAGTGACGCCCCCAG
GGCCCGGGCTGGGCGCGAGGTGGAGCCGCTCAGGGCTCCCGGGCTGCGGTTCGCCCGCTGTGCGAGGAGCTCC
CCTCTGCCTTCCGCGCCCGGATAAGAATCGAACGCGTGGTCCGGAAACAAAAGCGAACCATCCTCCGACACAA
ACACTTTAAAAACTGTACTCCCAGACGTACACATACACCGGAGACCTACAACCACAAGCACGCACACTCGCGC
GCGCACACACATACCACTCGCCCAAACTTCTCGAGCG
CGI: 289 range = chr2: 176652334-176656692
CGAAAAGGAGGCGGCGCAACGGCCACCCCTTCCAGCACCTCGGCTTTGTCCTTCCCGGGGAAGGCGGCCACAT
CCCTACCCGCCTTGCTCCTGAACGTAGTAAACAATCTCACAAACAACCACCGCTGCCCACGCTCTCCATCCGT
CCTCCCGGCCTTATCAGACCTCCGTTCTCCCGCACTCTTCGGGCAGGGTCCCTAATAAGCTCAGGCTGAAAGA
ACGTTTGCCACCTCCCCCACCCTCGTTGAAAGAAAAGGAAGAAAAACAGCAGCAGCGAGAAACCTCCGGGGCG
ACTCCTCCCCCGCCCCCAAGCACCAGCGCACAGCATCCCCCTCTGTCTTTGTTGTGGTTCTCCGTTGCTTCGG
GCCACGCCGTTCAGCCAAGCAACCCGGACCTGAGAGTGCACAGCCAGGACTAGCTTAGGGGGCGAGGGGTTGG
TCTTTGGGAAACCAAGCGCTCAGGACAGAGGTGGAAAGTGGGTCCCGGGAGCCAGAAAAGAGAGAGAAGGGCA
GACGGCTGGGTGGCAAATACAAAAATAGAAATAATTTAGGGGGATGCCCGCCAGGCTTTTGCGCCTGCTCCTT
CTCCCCCAATTCGGAGCAGGTTCCCTTCGGCCTCCCGCGCCCCGGGGCGCCCCCTGGCGGCAGCGGCAGCAGC
GGGCAACGCGCGGAGGGCTCAGGGGGCGCACAGGGGACTCCCGGGCACACTCAGAGAGGCGGGCGCGGCCCCC
TGGCGGTGGCGACGTAGTTATCTGGTGAGCGGAGCCTCGTCCCTCTGGTCCGGCGGGCTCACGGCCGTCTTAC
TAAGCACCGCGGCCGAGTAGGGCAGGAAGCCGCTCTCGGAACGCGGCGCCGCCGCGCTGCAGCCGAAGTCCGA
GCCTCCCCCGGCCCCGGCGCCCCCGCCGCCGCCGCCACCACCACCACCGCCGCCGCCACCGCCACCCCGGGAA
CCCAGGGCTGCGGCAGCTGCTGCCGCGGCTGCCGCCGCCGACTGACTGCTGTGGCAACTGAGGCACGAGCAGG
GTGCAGAGCCGCCGCTGGGGGGCGCGCCGGCCGCCGCCGCCGAGGAGGCCGCAGCCGCTGCGGCTGCCGCGGC
TGCCGCGGCAGAGGCCGCGCTGTTGAGCCCCGCGGCGGCCGCGGGAGCCTGGTAGAGACCAGGGTGGCGGAAG
CTACACAGCAGCTCCGGCCGAGAGTAGGGGTGCGAGAGGGCGCGGAAGGTGTCCAGTGGCCGGATGGAAGTAG
CGAAGGGCGACGAAGCCGCGGCCGCCGCGCCTGAGGCTGCAGCCGCGGCCGCCGCCGCCGTGACGCCCACGTG
CGGGTAGTAGTGCAGCGGCACGTGCGAGTGGAAGGGGTAGGGCAGGCTTCCGGTGGCGGCCGCGTGCGTCATC
ATGTAGGTGTAGAAGCTGGGGTCGGCTGGGTGCGGCCAGGACATGGCCAGGCGCTGCCGCTTGTCCTTCATGC
GCCGGTTCTGGAACCACACCTGCGGGGAGAGACGCGCCGCAGCCTGGGTTAGGGAGCGCCCCGTGTTCCCAGC
TCCTGTCCCAGGACCTCTGCCCCTTCCGGACCTCTGAATGGCTTGGTCTACTTCTCTCCGACCAAGCCCAACC
CCGAGTACCCTGTGGTCTCCCAGCTGGGAAAGTGTGGACGGCAGTGTGTGGACCGCCGTGGGCACACCGTCCT
CAACGAAGAGGGTCCTCTCCCCCGCGTCCGGCTGCTGCTGCTCCTCAGGCTTTTATTCCCTTACTTCTTGCTG
CACTTTTTTGTCCCAATCCAACCTTTCCTCTCCCTCCCGCCACCCACCAGTGCCGGTCTCGCTGAGCACCCGT
CTCTCAATCCCAGGATTTGTACGGGGATTCTGGGCAGCCTTTGAAGAGAGGCTGCCGCTCAGCTTTTCTGAGA
GGTCGCCGCGCGAAGTCTTGAGCCCTCCGAACTGCAAGGACCTGCCCCTAGGGGCACGGGTCCGATTTTGATA
TTGAAGGGATGATTTTGTTGGAATCGTTTGCCTTAAATGAGTGGGTAGAGCAATGTCTCCATAAACGGGGAAG
GGGACGTTTCCACCCCTCCCAACACTATCTAATAAAGACATCATTCGTCACAACTCTAAATTAAAGAAAGCCC
GATCAAACCAGAGGGAGACTTCCACACTCCTCCCCTACCCCGTGGAGATTTTTTCTTTTTTCTGCAGTGTCGA
ACGCTCCATGAAGGGCTCACCAAATCGCCTAACCTCCCGGCTATCTCTCCCAGACGTATAATAAAATTAATAA
CCTAAAGTTATATATAAATAAGGACAATTTCGTTGCATTTTTCCCCGCAGGAGGTTGCCCTTTTTTCGTTGCC
CAAGAGGAAAATGTTCAGGAAACTACTGTCTCAAACCAATCGATTTTAAAGATACAGTATCCTTTTCTCCGTG
TAACGATTTATGCGGAAAATAAATCTCCAAGCTCAAGAGCAAATGAAAAGTTTCACCTCTGGTTCCTGCTTGA
GGAACAAAGACCAACTGGGCTTGCCGCCTAGGGGAAAGTGGGGCCGTGGGTATGGGCGAGGGGGCATCTGGCC
AGGCGTTGGGCACAATGGAGCAGGGGCGAGTGCTTTCAGCATTGGAGTCACCATTCGGGGGCCTTCTTAGATC
CGTCAGGCCGGACAACCGTTCGGATTCGGTGGCCGGGAAATAAATAAGCCAATTCCTTTGGTGACTACCCCCC
GCGGATTTCCAGACCCTTAGCTAAATCTAGCCACCCAGAAAGGGGAAAGGGGAAAAAGAAACAATCAACCCAG
ATGCCCCCGGGGAGGCCAGAGCAGGCATGCACTGGAATTGATACCTTGATGGTGGTTTCGGGCAGGTTGAGTG
CCGCGGCCAGCTCGCACCGGCGGGGCCGCGACACATAGTTCTCCCGGTAGAACTCCTTCTCCAGGCGCGCGAT
CTGCTCGCGGGTGAACGCCGTACGGTAGCGCCGCACTTGATCCGCGCCAGAGCCGGAGCCACCCAGCGCCGCG
CTCCCGCCGCTGCCTCCGCTGCCTCCATGCAGGCTTCCGAGGCCTGAGCCCGACGCCGACGTCGTGGTGCCGG
CAGCCGAGCCGCTCTCTGCGTACCCTGGCAAACAAACGACCAACAGCGCATGAGTGGCTGTAGGACCAACAGC
CCGGCGCTGGCGCTGCGCGCGGATCGGGGAAGCCCCGTCAGGAAGGAGAGTCGCTGCCGGAATTGATGGGGTC
TGTCATGCTTACAAATTGCTGCCGTTAATGGAATCAATAAAGTTTGGGGAGCCCTTCATAAGCAAATAATAGA
AACGGAATTAGGAGATTTCTTTTTTAATAATTAGAAATTTTCAACCAAGGAGGAAAAGTGGCCGAGGGAAAAT
GCCTACCTCTGGGCGCAGTTTGGGAAGCTCTGGGTTTCCCATGGTCTGGAGACCGCAGGGCAGCTTTTTATAC
GGCCTCTAACCTTTATCTGAGTCTTCGGGGTTTCAAATATTTTAAGAGTTCCAACACAGCAGTAGCTCAAACC
CAAGCCAATAGGGGGTGAAATATACTTTTCAACTCTTTCTCCCGCTGACCTAAACAGAGACGCCGGCGAGGCT
TCCTCCGACTTACCCAGAAGAATGCCCCCTCCAGCCCTGAGGGCACAGGGGCAGGGGAGTTCAGAGTAGTTGC
CCAGGGTACCTTTCCCAAAAGCAACTCGGCTGCTGACTAGGGGTCTACCGGCTCGCTCGGGCTCTTAGACACG
AGCGCAGAAACATTTTCTCGGACTCAGGAGCGAGGGCGGGTGGGCCTGGTGTTCCAGGCTCCGCAGGCCTGAG
CCTGGCGGGAAAGCTCAAGGAGCAGAACTGGAAGGCACGGTCCCAGACATGCGTCCCGCCCCCGCCCGTGCTA
GCTCGGTGTAGCTTGCCTGTGGAGGGTCTGAGAGGGGAAAAGGCACCGGGAAAGGCTGGCGGGGGCCGCGGAG
GAGCAAAGAGGATGGGACTGGAGAGCGCGGTGCGGCCGGCGCGGTTACCTTTGCCATTGTTTTCCTTAAGCTG
AGCGGCGCCGAGGCCCCCGGGGGAGCGAAGCGCGGAGCAGCCCACCTCCACGTCGCTGCTCATGTCGGCCTCA
GCGGCCGCCTCTGAATAATGGCCCGGCTTCTTGCGGCTCTCGGCGGCGGAGGAGATTTCGGAGGAGACGGTGC
TTTCGCTGCCCGTGTGCTGCAGGTTGAACAAAGTGTCTATTTCGAATTTGCCCTTGGCGGGGAGTTCTCCCAG
AGCGCTGTGCAGGGGGGCAGACGGCAGGCGCGGGCTTAGGCGAGCCGGGTGCTGCGAATTTTCCAGGGCCTCG
AGCACAGCATTGCCAGCCGAGTTGGACAAATTGGAGAATCTCTTGCCCGCCG
CGI: 25 range = chr2: 176720618-176720921
CGCCGCTGTAAGTACCTTCCCGCTTCTTCCGAATCGCGAAGAGACGGTACTGATCGCGGGGAAGTGGTGGGCT
AAGGGGCCAAGCCAGCGGAGTGGGCGGATAGAAGAAAGGCCCTGCCTCCCCCACCCCACCCCCACCCTCCACC
CCCGGCCTCGCTCTGCGAGGTTAGCCCGCTTCGGGAGGTGGAGGCGCTAAATCGAGGTCCCGGAAAGCTTTTC
TGGGGCCTGGTTCACAGACACCTGCCTGAGAGAACGGTCCGCGGGGTCTCGCCCTTGTCTCCTTGGGCCTCCC
TAGACCTTCGCG
CGI: 20 range = chr2: 236438623-236438823
CGAATCCAGTCCCGGCCGGCGCTTTGAAGCCTGTGCTGTGCGATTTTCTCAGCAGTGAGGTAGGAATAGACGC
GGCTAATGACAGGAAGGTCGCGCGGGTGAGCTGACCTGTGTGTGGCGCAGCCTTGGGTTCCGCAAATAGGGCA
CCCACAGTAACACGTGTGGCGCCGACCCCGCCGTGCGCAATCGGGGCTTTATACG
CGI: 22 range = chr3: 11721578-11721824
CGATGGGACCGCGGCTTGACACGCATTAAGGAGCCACTGAAAACTCCATCTAAGCAGAAAAGCGGCTTAGTCA
TCCATGCGTTCTGGGCAAGTTATCCTGGCCGCACCACGTGGAACGGAGTAGATAGAGCTCGGGAAGCTGAGCG
CAGGGCGGACAACGGGAAGGCCAGAGCCGTGGGCAAGCACGCGGAGGGCAGCGAGGGGCACTGGCACCGGAGC
CGCGGGGAGGCAGGAAAACGCAGAGGCG
CGI: 68 range = chr3: 12983649-12984210
CGCTCCTGTCCCAAGGGCGCGTCTCTCTCTCCCACGCACAAACTCGGGTCCTGTTTGCTCTTCTCTCACCCAA
ACCCACAGTCTGGCGGACGCACCCCGCCCCGCAGGCAGCTTTCTCTCGCACGCCGGGCGCCCGGTCCCGACGG
TCACCCGCACTCCCGCACAGGCATCCCCACAGCCTGCGCCAGCCCACCGCTCAGCACCCGGGAAGGCCGCTCG
CCCCGCGCCGCGCCCTCACCCGCTGTCAAGCTCTAGCTCCAGAAGGGACTGGGTCCTCTCCGAGTTGCAGTGC
AGGCACCACATGGCGGCCGCAGTGGGAGCGGGCCGGGCCGGGAGCCGGGACCCAGGCCCAGCAGAGGCCGCCG
ACTCCCGCCAGCGAGCCGCCGGATCCCGGGGCCGACACCCGGCCACCCGGAGACCCGACCACCCGCCACGCGA
TCACGTCGGGGCTCCTGGTCCAGCGTCCGCCGGCTCCCGCGGCTCCGGCCCCAAGTCCGAGCCCCAGGCCAGC
CAAGCCCGCCCCTCCGCCGCCGCCCGCTTGGCGCAGCGCGAGGCCGGGCCG
CGI: 120 range = chr3: 25680561-25681574
CGCGGGGAGCGGGCTGGAGGATTCTGCAAGCACAGGCCCCTATGGAGCGCCCGTTCGGGGGACGGGATTTCCC
TCCCTTTCCCCTCCCCCGCCCGTTCGGAATTCCGCCCCCGCCGCGGGCCCGGAACAATGCAGCCGCCCGTCCC
GGGGACCAGCCACTTACCACCCAGGTCAGTGCCCCGTTGCCGCCGCCCACGCCGGCTCCCGCGCCGCAGCCAC
CCGACTTGGCCATGGCGAGTGCCTCCAGCTCACAGGCCCTGAGGCCGCAGCCGCCGCTCCCGCCTCCCTGCGG
GCCGCTGGGCCCCGCCGCTCCGCACCCACCGCTCCACTCGCCGCACTCCTAGCCGCGCCGACCCCCGCGCCCC
ATCGCGAAGATCCGGAGCGGACGTCCAGCCGAGCCCGCTGAGGAGGCCGCGCCGCCGGCTGCCCTCAAACTCG
AGGCGCGGCGTCCGCGTCGCCCGGGCCTAGCGCGGCGGCTGAGGAGAAAGCAGGGAGCGACCGGCGGCGGCCG
AGCGGCGGCGTTGCCTTCTCGCCCGCCCGCGGGCGCCGCTGCAGGCCGGGCTGAAGCCCGGGCGTGCGAGCCG
CGAGGGCGGCCGGGGAGCCCGAGGCGCTCGGACGTGGCGAGGACGCAGAGGTGCCTTGTCCTTCTCACACTCC
GCGAAGGCCAGCCACTCGAGTCGCCAGAGTAGTCGTCCCGGTCGCCGCCGCTGCTTCAAAGGCAGCCTTAGCC
TCGCTGCAGCCCCGATTTCCTCACACACACACACCGAGAGGGACAATAAACAGAGCCGCCGCCGCCGCCGCCA
CGGTCACCTCCCTCTTGTCCGGCATAACACCGCACACACACATTTGCACACCGGGGAGAGAGGGAGGGCGCGG
CGGCCGCCCCCGCTGTCAGTCAGCGCCATGCTGTCCAATCCGGGCCTTGTCGCCACAGCCTCTCGGCCAATCC
CAAAATTCCAAGCCCCCTGGAGGGGCGGGACCCGAGGGGGGAAACGTCATTGCGGGTAGCAACCG
CGI: 23 range = chr3: 148613030-148613264
GACCGGCGCTTCGCTAACAGCAGCGACCGCAAGAAGCACATGCACGTGCACACGAGCGACAAGCCCTATCTTT
GCAAGATGTGCGACAAGTCCTACACGCATCCCAGTTCGCTGCGCAAACACATGAAGGTAATCGCCGCACTCTC
GTCGCCCCCTTTGAGGCAGGAGCTCTCTTGGCTCTCGGCTTGGGGTCGGGCGGCGAGTGGCAGACAGGCGGTG
GCGGGAGCCAGAGGAA
CGI: 41 range = chr4: 4910534-4911092
CGGGCAAACCTCCGGAGGCCCCGGTGCACCGCGCGTCCAGCCGGCCCAACTCGAGCTAGAAGCCCCAACCACT
GCCCAGTGCCTGAGTTGCAGTCTTGGGTCCTTTAGAAACCTGGAGATGTGCGTAAAATTCAGATGCCGGTATT
CCCGAACTTCCCCAGGCCTCAGCATATCTCGGCGGCCTGTGGACAGATGGGAGGCTACCAATCGCTCCGGCGT
CCGCAGCCCGACCCCTGCCGCCAGACCCCGGACGTCTTCCGGATAATAAAGTTCCCGCTCTAATTCATTTTCC
CTAATCTGGACGCCCCTAATCTACAGCTTTTATTGCGCCCAGTTAAAAGTCGAGGGAATTCGCTGTCCCTCCG
CGCTCGGATAATTACCCCTAAATGGCCACGGCAGCCCCTTGTGTTTCCTGGAGATTAGAACCCCGCAGTCATC
AATGGCAGGGCCGAGTGAGCCGCCAATCACCTCCGCTCACTCCCTGAGAGCCGCTGGCCTGGGCCGCAGGAGG
AGAGGCCATAAAGCGACAGGCGCAGAAAATGGCCAAGCCCCGACCCCG
CGI: 300 range = chr4: 30330303-30333940
CGAGCGCGGCGGCTGGCTGACGCTCCCTCCCGCCTCCTTATCCCGGGCCCTCCTCCCTCGCTCTCTCCTAGTG
TGTAGTTTCGGCGGCTCGGCTGCTACTGCCGCCGCCGCTGCAGCAGCAGCGTCAGGGACAAGCCTGATCCGTG
AGCGAGCGAGCACCCAGCAGCAACCACCACTTTGGGCAACTTGCGGGTTTCCTGCTCGCGGGTAGCGAACGGG
AGATTCCCACTAGCGGTTCAGTGTCTCCGAGCCGCTGCAGCCCGAGGGGCGGCGGGAGCGCCCGCACCAGACT
CTCCCAGACGCGAAAAGGGACGAGACAACTGCGGAATTCACCAGCCGTGCCAGGGCACTTCCGAGGCCACAAC
CGACTGACACTTTTTCTCCCCTTGGCAAACTGGATTTTTTTTTTTAAGCTACTTGGCAGCTGTCTCTGACTCC
ACCTCCCCCTCCACCCCCGCCCGAAAGCCTTTGGCTTTTCTTCGGAAATCCAGACAGAATTGGGCATCTTTGT
TAATTGCCGTTGGGGACGCCCGGCCGTGCGCTTTCGCCGGCTAACGTCGCCTGTGCTCCGAGCCTGGTTTGCT
CACCTTTGAACTGCAAAGGGATCAAGTTCAGCTTGAGTTCCCTGCATTGGGAAGGAGAGAGAGCGTGCAAGAG
AGCGAGTGGGAGAGGGGGAAAGGGGAAAGGAGAGGAGGGAGGAGAGAGAGGAGGGAGGAGAGAGAAAGGGAGG
GAGGGAGGGGAGGGATCGAGAGAGAGCGGGGAGAGAGAGGCTGCAATCTCCTCCCTGAATCGCGCACAGCGCT
GCAGATCCCACTGCTCCGACATGCGGGCCGAATGCAGGTGAGAAAAGGCACGGACTCTGCGGCTGCGAACCCA
AACTTGGGCACCGCACGGTGCGCACTGCTCAGCCTTCGCCCCCGTGGGCGAAAGGCTGCTGCGGTTTCAGGCG
GCTGCTTCGTGACTAATGACCTTGCGCAGAGTTGTTAAGAAAAAAGAGAAACCCGCGCTCTCCGGGGTGAGAA
GGGACTGACTCTGGGCGTCTCTGAAGATGGCTCGGGCTTCTCTTTGGCGCGCCGGGGGGACCCTGACACTGAC
CGCTCTGTGACGCGAGTAGTCTCCCCTGCACCGTGCCCGAAGCGACGTGCCGGGGGATTTTTCATTCTCGATC
TGTTGACTGGCTCCCCCGCTGCATGAGCAGAGTCGGAGTTGAGACTGGCTTGTTGCTGGCCCCAGCGCCTGGT
GCAGGAAGCGACTCACGTTTGTCTGGGTGGCCGGAGCCGGAGCAGAGCCTGGGTTTGGAGTGAGTGCCTGGAA
CGTGAATTGGACTCAACTCGAGTAGCAGCAAAGACCAGCGGGCTGGCAGGCGGGGGAGGCTGCAGGCTCATTC
CCCACCTCTTCCCAGCCCCACTGCCCGTCTGCCGGAGCGGTTCTGGCCCCTTCCGACAGAGCGGGGACTAGAG
CCGGGGATTCTCCGCCCGCTGAGGGGATGACTCTGGGTTGGGGGAGCGCCGAACCCGCGGCGCGCAGTGTCCC
GTGAACTGTGAGTACTGCGACTGAACGGCGGCAGGCGAGCGGGCGATTAGCACCCATTGCATGAATTATGAAA
CAATAACTTTCGGAAGAAGCAGGAGGAAAAAAAGAAGCATCTATCGCTGCCCTCCCACCCCCATTCCCGGCCA
ACTCTCCACGCCGCTTTTGCCCCCTCCCTCCCCTCCCTCTCGCTCCTTCCTTTCCGGGAGAGGGGAGAGGACT
CGGGGGAGGGCAGGCGGCCGGCCCCGGAGGAGGGGGGCGCCGAGGGGGCTGTGGTTAGAAGGAGCAGTAGCAG
CAGCAGCAGGAGAAGATGCTGAGGATGCGGACCGCGGGATGGGCGCGCGGCTGGTGCTTGGGCTGCTGCCTCC
TCCTGCCGCTCTCGCTCAGCCTGGCGGCCGCCAAGCAGCTCCTCCGGTACCGGCTGGCCGAGGAGGGCCCCGC
CGACGTCCGCATCGGCAACGTGGCTTCAGACCTGGGCATCGTGACCGGATCGGGTGAGGTGACTTTCAGCCTG
GAGTCCGGTTCCGAGTACCTGAAGATCGACAACCTCACTGGCGAGCTGAGCACGAGCGAGCGGCGCATCGACC
GCGAGAAGCTGCCCCAGTGTCAGATGATCTTCGACGAGAACGAGTGCTTCCTGGACTTCGAGGTGTCGGTGAT
CGGGCCCTCGCAGAGCTGGGTGGACCTGTTTGAGGGTCAGGTCATCGTGCTTGACATCAACGACAACACGCCC
ACCTTCCCGTCGCCCGTGCTCACGCTCACGGTGGAGGAGAATCGGCCGGTGGGCACACTTTACCTGCTGCCCA
CAGCCACCGACCGCGACTTCGGCCGCAACGGCATCGAGCGCTACGAGCTGCTCCAGGAGCCCGGAGGCGGCGG
CAGCGGCGGCGAGAGCCGGCGCGCCGGGGCGGCCGACAGCGCCCCCTACCCCGGGGGCGGCGGGAACGGCGCG
AGCGGCGGCGGCTCGGGAGGCTCCAAGCGGCGGCTGGACGCATCAGAGGGCGGCGGCGGCACCAACCCCGGCG
GCCGCAGCAGCGTGTTCGAGCTGCAGGTGGCGGACACCCCGGACGGCGAGAAGCAGCCGCAGCTGATCGTGAA
GGGGGCGCTGGACCGCGAGCAGCGCGACTCCTACGAGCTGACCCTGCGAGTGCGCGACGGCGGCGACCCGCCT
CGCTCCTCGCAGGCCATCCTACGGGTCCTCATCACCGACGTGAACGACAACAGCCCCCGCTTCGAGAAGAGCG
TGTACGAGGCCGACTTGGCTGAGAACAGCGCCCCGGGGACCCCCATCCTGCAACTGCGCGCAGCCGACTTGGA
CGTGGGGGTCAACGGGCAGATCGAATACGTGTTCGGGGCGGCCACCGAGTCGGTGAGGCGGCTGCTGCGCCTT
GACGAGACGTCCGGCTGGCTCAGCGTCCTGCACCGGATCGACCGCGAGGAGGTGAACCAGCTGCGCTTCACGG
TCATGGCCCGCGACCGCGGGCAGCCCCCCAAGACCGACAAGGCCACCGTGGTCCTTAACATCAAAGACGAGAA
CGACAACGTGCCGTCCATTGAAATCCGCAAGATTGGGCGCATCCCCCTCAAGGACGGGGTGGCCAACGTGGCC
GAGGACGTTCTGGTCGACACCCCCATCGCTCTGGTGCAGGTGTCCGACCGAGACCAAGGCGAGAACGGGGTGG
TCACCTGCACCGTGGTGGGCGACGTGCCCTTCCAGCTCAAGCCAGCCAGCGACACCGAGGGCGACCAGAACAA
GAAAAAGTACTTCTTGCACACCTCGACCCCTCTGGACTATGAGGCCACCCGGGAGTTCAACGTGGTCATCGTG
GCGGTGGACTCAGGCAGCCCCAGCCTCTCGAGCAACAACTCCCTGATTGTCAAGGTGGGAGACACCAACGACA
ACCCGCCCATGTTCGGCCAGTCGGTGGTGGAGGTTTACTTCCCTGAGAACAACATCCCGGGCGAGAGGGTGGC
CACGGTGCTGGCGACAGACGCAGACAGCGGTAAGAACGCCGAGATCGCCTACTCGCTGGACTCCTCTGTGATG
GGGATCTTTGCCATCGATCCCGATTCTGGGGACATCCTGGTCAATACCGTGCTGGACCGCG
CGI: 21 range = chr4: 41678680-41678940
CGTCACCAGTTACTCCCGTTTAGCCAACGAGCTGCGTGTGAGCTGCATGGAGCGGAAAAAGGTCCAAATTCGG
AGCTTGGATCCCTCCTCTTTGGCGAGCGACCGATTTAACTTCATTCTGGCGAGTACCAACAGCGACCAGCTCT
TCGTAGTGAACCAGGTCGAAGTCGAAGGCTCCAAGTACGGCATCATCAGCCTGCGAACTCTGAAGATCCCTTC
GTTCCACGTGTACGTGCTCAGAAACCTCTACGTCCCCAACCG
CGI: 217 range = chr4: 85636684-85639823
CGCAACTTCCCGCAGTTACTGCCGCTCAGCCGCACTAAGGAGGTCCGGAGACTTGGAAGAAACTTCGGAGACT
CGCTGAAAGGCGAAGAACTGAGCGAGAAAAGGACCCCAGGCTGGGCCCTGAAGTCCACCTGGAAGGCTGGGAG
CCTCCGCGGCGCTGCGGCCTACTACCCCGAAGACTAGCGTGATCTTGGGGCAACTCAGTTTGCCTCAAGCAAG
GTCTTTGCGGGATGGTACATTTTCCCCAGGCCGTGTCCCTTCATCTCACTCTTCTCCTGGCTCGCTCTTGTGT
TAGGGTGTTGAGCTCCACGATGTCCCCAAATGTGCCCGGACGCAGCGTGTGCCAGCCCCCAGAGTGGAGGCAG
GTGGGAAAGCGCGGGCCCAGCGCTGGTGAGCGGCTGGAAGCGCTCGCCCTGCCCTGGGGACGCTGGACTGTCT
TCAATGGGCTCACCCAGGCCGAGTGTACTCGGGCGGCGAGGGCGAAGAGGTGAGGTGGGGACACCCCAGGCGG
AGACGTGCATGCAAATACACTCACTTCCCGGGCGGTGGAGGGCTCACCGCTGCCGGGCCTCACTGCTTCGAAG
AGAGGCAGCGGGTTAGGCTGGCGAAGGCGGAATGGGGCGCTGGACGACAGGGAGGAGCCGGGAAAGCAGAGAT
GCAGTGGCCTCTCCTCCCCTCTCCTCCCCATCTTTCTAATCCAGGCCAGGCCTGCGGTCCTGGCCAGGCCGTT
TCAGGAACAGCCAGGGCCTCGGACGAGACACACGTCCCTCACCGCGTTGTGGTCCACACGAACACACACACAC
CGGCTCAGCCCAGGCGTACTCAAGACTTAGAGAGAGGGAGGCGCTTGGATACAGCCACGCGAGCTCAGAAAAG
CGAGAATCCCTTTCTGGAAGCCCTGGCCCAACCTAACTGGTGTGATTCCGGCGCTGTCAAACTACTGGGGCGG
GCCACAGGATGGACTGAGCGGCATGCACACCAGGGGCCGCGACCCGGGAGTGGGCAGAACAGGCACGGCAGGC
AGGCATCGGGGCGCGGGTGGTAGTACTCACGAGGGGTACAGGCCAGGCGTGCGTCCCTCCAGGGCGGGCTCTG
CATCACTCCGGGCCAGAAGATGGGCGTCCGGCCAGGCAGCTCAGCCAGCGGCTTGGGGTACCGGCCCACGGCG
GCCACGGCCGCGGCGCTGGGGCTGAAGTAGAGCCCGGGCGGCGGCGGCGGCGGGCTCAGGCTGCTAAAGCGTG
GCAGTCCGGCCAGCAGCCCCGCCGGGGATGAGGCGGCGGCTGCGGCCGCGGCAGCAGCCGCGGCGGCGGCAGA
GGCGGAGGAGGCAGAGGCGGACGAGGAAGAGGAGGAGGAGGAACCGGAGGGCGAGGCGGAGGGCAGGGCGGCC
CCCGAGGCCACGGGCATGGAGGGCCGGCTCAGGATATCGTTGATGCCGTGTGGGGTGGCGGCCGAGAGCTGCT
GCGGGGGGCTGCCGAGGGATGAGAGCCCCCCCGTGGCCGGGGGCTTCAGGCCGCCTGGGTTGTGGGTGCCCAG
AGGCGGGGAGGGCGACGAGGAGGACGACGACGAGGACGAGGAGGAGGGGGGGCCGGCAGGCAGCGGGGGATAC
GCGGCAGGGTACAGCGGGGTCTTCATCTCGGCCATGCTGTGCAGGGCGGCCAGGGGAGGGCTGCTGAGCAGGA
ATGCGCTCTGCCGGGTGCCCTCCATTGCCCCCACCGCTAACATCCCACGGCCACGCCGGAGACCGTAGCCTTG
CAGCGAGGGCGCTGGCTGGTGCCCCCCGCGGGGCTCAGAGGAGCCGGAAGCGCCGAGGGCGCGAGCGGAGAGG
CACTCGGCGCGCCCGGAGGCGAGCTGCCAACTGAACCAAAAATGCCGCTGCCGGGAGTTGCTCGCCTAGCTGC
GCAGCAGAGATGTCCAAACCCTCCACGCGGGAGGCGGCAGCTCGCCGAGAAAAGCAGGCGTCCCGGCGGGCTA
GGCAGTCCTTTCGTTCCGCGAGTCCTAGATTCGATCCCTGGCTATTCTCTCTTCCTCACTTTTCCTAGCTGTT
CAAAGTGCGCTACTTCTCATCTTCTGCCCCCGGGAAATAAGCAAAACAAAACCCAGGCTGGCTCCGGAGAGTT
TGTAGCAAAGTTAGTTGCCGAATCTCCACTTTGAAGTTGGAGGGTGGGGGTGGCTTGCTTTCTTTGGGGAGGT
TCAAAGGACGCCTTGTGCAGCCCGTGGCGCTCCTCTGATCTTACTGGGATGCTCTGCTCTTTCGGTCGCGCGG
CTGATTCGCATTCGACGCTCACTGTGCCCGGGGAGAAAGCGCATCCAGCCCGCGGGAGATCTAGCCTCTGTGC
GGGCTTCCTCCGCCCACGCTGCCCCGGGCTGCTGCGCCAGAAAGGGCAGTGCCACGGATCCCCGCGGCTCCCA
GGTCCTCACCTCCACCCGCCTTGCCCTCTGGCCCACGGGGCACTGGAGTTGCAATATTGAAAAGAAAAAGGGG
GAGGAAAAACACAGAAAAACAAAAGACTAAGTGTGAAAAGTCTGACGGCTGGGTTTCGGCGCCGCTCGTCAGT
CCACTTCTGCAAACGGGCCCGGCGACCCCCGCCCCACCCCCGCTCCCTCTCTCCCTCTCACTCTCAGCCTTTG
ACTCTCCTCTCTGGCATTTTCTTCGCGGCTTCCCAGGCTTCGGTCTTCTAAGTCCTGTCCTCTGGCCAAACTG
ACCCTCTCCGCGGCTCCTCCGCTCTTTCTCTCCTTTCCTCTCTCCCTCCGGGCCTGACAGTTCAGATGAAGCT
CTCAAAGGTAATAAAACATTTGCATCACTCCCTACCCCTCTTTAGCTGGGGGACGAAAGGGAGGGGGAAGTGG
GGGACCAAAATGAGAACTTTGAGGGACGTCACTCCGAGGCTGCGGGGGCCGGCGAGCCGGGCGCAGGCCGGGG
GCGTAACCACCGTGTCCAATAGCTCGCCGCCTCGATCCTTGCGTCGCCCCTGGGGCTCGCCCACTCGGGGGCG
CCGCACCCTCTGATTGGCTGAGGCGGGCCAGGCGTAGGGCCGCGCCCGCCTAGTCCCCTCCCGCTCCCTACTT
CTTTCTCCTGTGGGCGGGGCCAGGAGGGGCGGGAGCTGGTGAGTGGTGCGGTTCCGCGCTGGGGCCAGTGGCC
G
CGI: 39 range = chr4: 94974810-94975333
CGCGGTGCGGAGCGTCTGGAGCGGAGCACGCGCTGTCAGCTGGTGAGCGCACTCTCCTTTCAGGCAGCTCCCC
GGGGAGCTGTGCGGCCACATTTAACACCATCATCACCCCTCCCCGGCCTCCTCAACCTCGGCCTCCTCCTCGT
CGACAGCCTTCCTTGGCCCCCCACCAGCAGAGCTCACAGTAGCGAGCGTCTCTCGCCGTCTCCCGCACTCGGC
CGGGGCCCCTCTCCTCCCCCAGCTGCGCAGCGGGAGCCGCCACTGCCCACTGCACCTCCCAGCAACCAGCCCA
GCACGCAAAGAAGCTGCGCAAAGTTAAAGCCAAGCAATGCCAAGGGGAGGGGAAGCTGGAGGCGGCAGAGGCG
GCGGCGGGAGAGCTGTGGGGTTGTTCAGGAAAAGTTGGGCTGGGGGCTGAGGCACCTGAAGCAGTGAACCAGG
ACTAGGTAGGAAGCAAGAGCATCCTCCTGCGCAAGCGGAGACGCAAACGCGCTCCTGAACCCATGCAACCGCC
CGGCCCAGCGCCG
CGI: 162 range = chr4: 134291113-134293078
CGGAGCCAGACCTGACGGTGGAAATCTCTGAGAGCGCCACGCCAGGCACTCGCTTCCCCTTGGAGAGCGCATT
CGACCCAGACGTGGGCACCAACTCCTTGCGCGACTACGAGATCACCCCCAACAGCTACTTCTCCCTGGACGTG
CAGACCCAGGGGGATGGCAACCGATTCGCTGAGCTGGTGCTGGAGAAGCCACTGGACCGAGAGCAGCAAGCGG
TGCACCGCTACGTGCTGACCGCGGTGGACGGAGGAGGTGGGGGAGGAGTAGGAGAAGGAGGGGGAGGTGGCGG
GGGAGCAGGCCTGCCCCCCCAGCAGCAGCGCACCGGCACGGCCCTACTCACCATCCGAGTGCTGGACTCCAAT
GACAATGTGCCCGCTTTCGACCAACCCGTCTACACTGTGTCCCTACCAGAGAACTCTCCCCCAGGCACTCTCG
TGATCCAGCTCAACGCCACCGACCCGGACGAGGGCCAGAACGGTGAGGTCGTGTACTCCTTCAGCAGCCACAT
TTCGCCCCGGGCGCGGGAGCTTTTCGGACTCTCGCCGCGCACTGGCAGACTGGAGGTAAGCGGCGAGTTGGAC
TATGAAGAGAGCCCAGTGTACCAAGTGTACGTGCAAGCCAAGGACCTGGGCCCCAACGCCGTGCCTGCGCACT
GCAAGGTGCTAGTGCGAGTACTGGATGCTAATGACAACGCGCCAGAGATCAGCTTCAGCACCGTGAAGGAAGC
GGTGAGTGAGGGCGCGGCGCCCGGCACTGTGGTGGCCCTTTTCAGCGTGACTGACCGCGACTCAGAGGAGAAT
GGGCAGGTGCAGTGCGAGCTACTGGGAGACGTGCCTTTCCGCCTCAAGTCTTCCTTTAAGAATTACTACACCA
TCGTTACCGAAGCCCCCCTGGACCGAGAGGCGGGGGACTCCTACACCCTGACTGTAGTGGCTCGGGACCGGGG
CGAGCCTGCGCTCTCCACCAGTAAGTCGATCCAGGTACAAGTGTCGGATGTGAACGACAACGCGCCGCGTTTC
AGCCAGCCGGTCTACGACGTGTATGTGACTGAAAACAACGTGCCTGGCGCCTACATCTACGCGGTGAGCGCCA
CCGACCGGGATGAGGGCGCCAACGCCCAGCTTGCCTACTCTATCCTCGAGTGCCAGATCCAGGGCATGAGCGT
CTTCACCTACGTTTCTATCAACTCTGAGAACGGCTACTTGTACGCCCTGCGCTCCTTCGACTATGAGCAGCTG
AAGGACTTCAGTTTTCAGGTGGAAGCCCGGGACGCTGGCAGCCCCCAGGCGCTGGCTGGTAACGCCACTGTCA
ACATCCTCATAGTGGATCAAAATGACAACGCCCCTGCCATCGTGGCGCCTCTACCAGGGCGCAACGGGACTCC
AGCGCGTGAGGTGCTGCCCCGCTCGGCGGAGCCGGGTTACCTGCTCACCCGCGTGGCCGCCGTGGACGCGGAC
GACGGCGAGAACGCCCGGCTCACTTACAGCATCGTGCGTGGCAACGAAATGAACCTCTTTCGCATGGACTGGC
GCACCGGGGAGCTGCGCACAGCACGCCGAGTCCCGGCCAAGCGCGACCCCCAGCGGCCTTATGAGCTGGTGAT
CGAGGTGCGCGACCATGGGCAGCCGCCCCTTTCCTCCACCGCCACCCTGGTGGTTCAGCTGGTGGATGGCGCC
GTGGAGCCCCAGGGCGGGGGCGGGAGCGGAGGCGGAGGGTCAGGAGAGCACCAGCGCCCCAGTCGCTCTGGCG
GCGGGGAAACCTCGCTAGACCTCACCCTCATCCTCATCATCGCGTTGGGCTCGGTGTCCTTCATCTTCCTGCT
GGCCATGATCGTGCTGGCCGTGCGTTGCCAAAAAGAGAAGAAGCTCAACATCTATACTTGTCTGGCCAGCGAT
TGCTGCCTCTGCTGCTGCTGCTGCGGTGGCGGAGGTTCGACCTGCTGTGGCCGCCAAGCCCGGGCGCG
CGI: 308 range = chr4: 149582663-149586506
CGGATTACGCAGCCACTTCTCCCTGCAAAGTGCACGCTCCCGCGCCGCGGCCGCACGCCGAGCACGGCAAGCG
GTGCCCCGCCGCGCGCCCCTACACACCTGCCTCGGCCGGGGTCCGTCTCTCGCCGTCTACCTGTTGCAGCGCT
TGCCACCGCCACGAAACCCCTGCTGCGGAGCCCCCCTAAATCCAACCACATCCAGGCCAGCGAGTGCCGCTCT
CCCTGCAGCGGGAGAGCCCGAGGCAGCAACGCTCTTGCACCCAGGTGACTGACTGCACGGGCTTCCTCTGAGC
AGCCTGAAGTTGGCTCCCGTCTCCCGGGCCCAATGACACCCCGGGCGCGGAGGGGCTGAGAGGAGGGGGCAGG
GGCAGGGGCAGGGCCAGGGCGGGCAAAAAAGGGAGGGAGAGAGGGCGGGCGAAAGCCCGGAGGGGGAGTGGGC
CAGCTGGAGGGCTGGCCCTTTTAAAAGCGGGTCACATGTCCAGATAAAGTTCAGGTTGCTATCCCGCCCCCCT
GAACCCTTCCTATTGGCCCGAAGAGAAGCAAGGCTCCACGCCGCACGGGTCAGGCGGGCTTCTTATTGGACAA
TCCAGGCTGTCAGTCACCAGGCGGGCGACATGACTGATACAAAGTTGCTGCGACACAGCCTGGACTCGGCAGC
TTCCTTAAAGCCGCAGCCGCGGCGGGAGCTTGGGGTGCCGGGCGGTGGCTACATCAGGCGGCCTCCGCACGCT
GCCCCCACCCCCATCGCTCGGCCGCCCCAAACTTGCTTACGTCCACCCTGCTCTCCTTCTGACCGACCCCAGG
ATATCTGGAGAGATGTGAAAAGTGTGCTGACGCGGAAGAAGTCGGTTTTTCCGCGAGCAAAGTGTCGTCCCCT
CACGCTCTCCACCTGCAGCTCCAGGTGAGCTGCAGCCCAGACCCTGGCGCCGCCCAACAGCGTCCGCGCGCGG
GGAGGACTCTGGGTGGGCTTCACCCGACCCTCGAGGTTCCTCTCCCAGCCCCTTTCCACTGTCTCCAGAGTTA
CCTCTCAGCAGAGCAGCAGCAGCCTTCGCTGCCAGCGAGCAAGACGATCACGTTCACTCGATTTGAATTTAGT
TGTTTTAACCGTGCTGGAAAAACCCTTTAAACACAGCTTTCCTCCCATCCCTTAGACCCCTAACACCAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAGAGAGAGAGAGAAAGATAAATGAAAGAAGTGGCAGGGTCAAGAGCTG
CTCCTCTACTTCCTTATAATTTTGTCACTGTACTTACTACTTTAGTATTGGATTTTTCCACTAGTTCAATTTG
AAAGCAAGCTTACCATCGAGGATATTCACGTTATAATGGGTGGAGGGGGTGGGTCACATAAGTGGGAGAAACA
GACAGGAGGGGGGAAGGAACCAAACTGTTTTCTAAGGATCGGTTGTCTGCATGAAGAAATTTCGGTTTCCCTC
CAACCGCCCCCTCCTCGATTCTCCTCCCGCCCACCCAAATGCTGCAGTTACTAAGCAAAAGGATGGGGTTCCT
AACTTTGATTTCTAAGGACTTTTAGGCTTCTCATGTAAGGCCCCGTTTTAGGCTCCCCGCTGGCCCGGAGTCA
GCATCAGTGACGTATACACCTAAATCTGGTCCCCCGGCCCTCGGCGACCCGCAGCCCGGCGGCGGCAGCTGTG
CGGCCTCCCGCCTCACCCTCGCTTCGCGCCCGCCAAAGCCCGAGGCGGGGGACCGGGGGACACCCTGTGCCCA
AAGGCCCCTCCTCTCCTTAACAGTTAGTTAAGCTCCGGGATTCCGGACCCCTAACCCAGGGCTGAGACTTGAA
CTCTCAGCCGCTCCAGTCAGGAACTCCCTGGAGATAGGGGCGACAGCGGCAGCGCCGCGAGCTGGTCCTGACC
CCAGACTCTAATGCCCCTCGGTCCCCAGCTTGGAGCTGCCCCCGGCGTCCCCGCAGCCAGGAGTCCCCGCCGA
GCGTCCCAACTTTCCCGCGGGGCCCACCGTCACGCGCACTCTCCCGGCCCAGCGAACTGGGCATCGATCTCAC
GTCGGCAGAGCGCGGGCGGCGGGCGGGAGCAAGGGGAGTCCCGGACCTAGAGCCTGGGCACGCGAGGCGGCGG
CGGCTCCGCAAGCGTTGCCGAATTATTCATTATTAAAGGAATGGACGTGTCTCTTTTACTAAGTTTTTATCTC
CTTTGAGGAGGGCCGGTCTTGCCCTGGATCTCAGCTTCTTGCAAAATCTAGGTTAGAACCGTGCAGGGGCAGC
CGCCGCGATCACTCGCCCGCCACCCAGCACCCTTGCCCCAGGGCCGCCAGCGGGCAACTCGTCTCCTGCCCGC
ATCCCACCTCCGCTCGCCAACCCGCGCCCTCTGCCCTGGGCGCGCAACCTGCCTTGCCCGGGGCCGCCCCTGC
GCTCTCCGGACCCCCTCTCGCCGCTGTCAGCGCAAAGTGACTGTCGCTGCACTCACCTTTTCTAGGACATGGT
GGGGAGGCTGGGGCGGGGGAAGGGGAACGGCTAGACTCCCGCCGCCGCTGCTGCCGCCGCCACCAGCAAGTCC
AATATTGGCTGATCGGCGGTGAGGATGGAGAGGATGATAATCCCGGCAGTGGCAGTCGCCCTGCTGACGGTGG
GTAGAGCAATAGTGCTGTTACCCTACAAGAGGCGGCGAGGCAGCGGCGCCAAATCGCGCAGAGGGGGACGCGG
GCACCCGCCCGCCCCCAGCGGCGGCGGCCGGGCCTCTGGCGGGCCCCTCTCCCGGGGCTGCGCGTCCGCTCGG
CGTTGACAGCGGCGTCCCTGGGAGCCGGGAAGTCCGGCAGGAGGATCCCGCGCCCGCCGCTCCGCAGCGCCAC
TCTCCGCGCCCCCTCCCCGGGCCCTGGGTGGCCGGTGACAGCTCCGGCGGCCGAGCGCGTGTGTGAGGGGGCG
GTCGCAGGGGGAGCCTGCGCCCCCCTCCCCGGGTCACGCCCTCACGAGCGGGAGGAGGCGGCACCGCGTCCGG
CCACCCGCGGGTGGGAAACGGGCAGGGGCGCCGGCAGCCGCCCTCCCACTACGGCCACTGACAACCTGGAGGC
CAAAGGAAAACTGAGCCCAAATGCACGCACCCCCTTCAGCCCTGCCCGCAGCCCTCCAAAGTCCGGCCCTGAC
CTCGCGCCCGGCTTCAGGTGCAGTTCCCACCTGCGGGGGGAGGCGAGGGCTGGGGACCTCGCGCGGGGGGCGG
GAGGGAAAAGTTTTCTTTTCCTGCTCCTCGGCTGCCCACCCCGCCAGGCTGCTCCTCTCCCCGCCCCTCTCGG
GCTCGCCGCGCCTCTGCCCCACCCCCGCCGTGGGGGGGCGCCGAGGAGGGAGCGGGCGTCTGTGCGCGGAGGC
GTGCGGGGAGCTGGCTGGGGCGCTGCGGTCGCGACCGGTCCCCTCGCTCTGACGGCGGCTCAGACGCCCGCGG
AGGCGGCTCGGCGGGGCAAGCCGAGGAAGGGGCCGAGAGCCGGGACCCCTCCTCCTCCGCTCGCGGCGCGCCG
CGCGCCCCCGCGTCTCCTGGCGCGCCCCCGCGCCCTCGTGCCCGCTCGGGCAGACACCTACGCAGACGCGAAA
GTGAAAGGGGGGCGACTGGGCCCGGCAGGCGGGCGGCCGGCGGCGCGCGGGCACGCGGCAGGGGACAGAGGAT
GGATGGGTGAACCCGGATCCCGGGATTCTCCCGCGCCCGCTGCCCCTCTGCGGAGCCTCCCCGGAGTCCCACG
CCCCCACCCCGGCCACGGAGATCACCACGTCAGGAGATATGTATGCGTGTGCATGTGTGTGCGCGCGTGTTCA
CGCGCGTGTGCGAGGTACGCTTCTGCCCCAGACTCTTCCCCCGCACCG
CGI: 44 range = chr4: 154436043-154436665
CGAGAAGCTGAACGAGCTGGCCGACCAGGACTTCCCCTTGCACCCGCGGGAGAACGACCAGCTGGATTTCATC
GTGGAAACCGAGGGGCTGAAGAAGTCCATCCACAACCTCGGGACGATCTTAACCACCAACGCCGTTGCCTCAG
AGACAGTGGCCACGGGCGAGGGGCTGCGGCAGACCATCATCGGGCAGCCCATGTCCGTCACCATCACCACCAA
GGACAAAGACGGTGAGCTGTGCAAAACCGGCAACGCCTACCTCACCGCCGAACTGAGCACCCCCGACGGGAGC
GTGGCAGACGGGGAGATCCTGGACAACAAGAACGGCACCTATGAGTTTTTGTACACTGTCCAGAAGGAAGGGG
ACTTTACCCTGTCTCTGAGACTCTATGACCAGCACATCCGAGGCAGCCCGTTTAAGCTGAAAGTGATCCGATC
CGCTGATGTGTCTCCCACCACAGAAGGCGTGAAGAGGCGCGTTAAGTCCCCGGGGAGCGGCCACGTCAAGCAG
AAAGCTGTGAAAAGACCCGCAAGCATGTACAGCACTGGAAAACGAAAAGAGAATCCCATCGAAGACGATTTGA
TCTTTCGAGTGGGTAAGGAGAGGGCTTCTGTGCCCGACG
CGI: 122 range = chr4: 174686622-174688044
CGGCGGGTACGTTGGGGATGCACTCGCGCAGTTCGGCGAAGGCGCTGTTGATGCTCTGAGTCCTGCGCCGCTC
CTTGCGGTTGGCGGTGCCTCGGCGCTTCACCGGGCGCGGCCCCCCCAGGCCCGGGGGCCCGGCGCCCGGCGGC
ACCCCCCCGTAATGGGAGTGGTCCAGGCCGGCGGCGCCGCTGGCATACTCGGGGCTGTAGGACAGGGCCATGC
TGTAGTCGGGGGGCGACATCTCGGGGTGGCCGATGAGCCAGCCATGGAAGTAGGGGTTCTCCTCATGGCTGCA
GCGGCTGGCGGCGGCGGCGGCAGCTGCGGCGGCGGCGGCGGCAAACGGGTAGCCCTCGTGGTGCACCACCGGG
TGGTGGGGAAAACCACCTACCAGACTCATTTCGCCCTCCGCGCCCCTCCACGCGCCCCAGCGTGCGCGCAGCC
CCGCCGCGCCCTCGGCCCGGGCCCCTGCCTCAGCGCTCGGCGTCCTCCCCCACCCCCCACCCCCCAGCCCCCG
GGCGCCCGGGCCCGCCCGGCAGCCGCAGAGGGGGCTGCTGCAGCCCGGGCCCCGTCCCCCCGCCTGGCCAGCC
GGGCCCGCCTCAGCAGCGCTGCGGCCGCCGGCTCCCCATGGGGCGCGGCGAGCTGGTCCTGGCACCGTGCGCC
CCTGGCCGCCGCCGCCGCCGCCTCCGGTTCCCGCCTTGCTCCACGGCCCGCGCTTCGGCTCCTGCTTCCCGGG
CTGCTGCGCGGAGGCAGAATCCTCTCGTGCTCATACAAAGGTGCCGGGGCTCCCGCGAGGCTGGTACGCGGAG
TCTCGGGAATCCAAGCCCGGGCCGCGGTCCTGGCACCGAAGCTAACCCGGAATCCAGGGGCGAGTCTGAGCCG
CGGCTGGAGGAGCCGGTCCAGCTGTGCCGGGGGGCGGCGGGGTCGACTGCTCACTGCAAAGCTACCTCCGTGC
GACCCTCCCCTTCCCGCCTCTTCCCCTCCCCCCACCAGCCCGATCTGGGTTCTTGGGCGCTTATTGTTTTAAT
GAAATTTTTGGTTGTTGTTGTTTTGGTCCTTAAATGTGATTTTAGCTGCGAGTAACGTGTCCTCGCTCCTCTC
GCGCTCTCTCGGAGGGTTTTCAGAGAGGTCTCAGTGCATCCATTTTCTCAGATCCTCTCCTTTCGGGGCAAGG
ATCTGGGGCCCTGAATGAGCCTTGGAGCTCGAAGACCGCGGCTCGGGCTCTCGGAGGGCTCTGCGCGGTGGCC
GAGGAAGCTCCGGGGTGACGGCGGTGGTTCTCCTGGGCTGGACGACGTGAGGGGAGCAAGCGGATTTTCCCAG
CAAGATCTCCATGTACAGCTACATCTTTAGGGCCGCTCGGGTTAATATATGTCGTCAGAGGCTCCTCACGCCA
ATCCCGGGGCGGCAGGGGCGGCGCCTCGAGCTCTCG
CGI: 245 range = chr4: 184255825-184258373
CGAGATTGGCCGCAGATGCCCCGACGGGATGGCCTGGGGAGCCGAAAGCTGTCCCCAGCCCCGGACAGCTACT
GCCCACGCCGCGCAGGCCAGCCTCACACAGTAGCGAATCTCCTTCACGCGACTTCCTCGCAGGCCTGTGAACC
CGCAGGGGAGGCGGAGGTCGGTTCAAACCCTGCGAGAGCCCCTGCCCAGCGCGGAGTCCTGCACACGGTGGAA
AGTCCTTACGCATTAGCGGGCAGGATTAAACGACTTCACACCACGAGGTGCAAGACTGGGCTTCGGGGCCTTC
CTCGGTGTTGCTATTTTAAAAGAAGCTGCTCAGTAACCCAGAAGAAGATGACGGGGGACGGTGGTGTAGACCC
GGCTGGAGAGGAGTCCAGGGCCTGGGAGGCGCCCCCTCTGACTGAGGGGCTGGGGACCCTGAAGCTTGGCGTC
CAGGCCCCGCCAGCGCTGCACCCGGCATTGTCCCGCCTGGGGCAGGCGTCCGGTCCCTCGGCAGTGCGGGCCA
GCACGTACGTAGTAGCTGCTGAATAAATAAATGCCTATGCAACAGGGAACGTCCCGGCCCACCCCGGCCGGGC
CAGGGCCTAGGAAGGGCGGGCGTCCGGCGCCGCCGTGGGTCCCTCCGGCGTGGCCGCCCACACCTCCTGGCCA
CGGCGGGGCTGCGGTGGGGGGACATCCTGGGGCGGGCGGCTGGACGGAAGGGACTAGAGTCGGGGCGCGTCCA
CGGCCAACCGCCCCGAACCAAGCAGGGGAGGCCAGGGACCAGGAGCTTCCGGGGCCCCGCGGCTGGAGCGCCC
GGACGCGAAGGGGCGGCGGGTGACGGGGCGCGGTGCGGGCGGCTACAGGGCCGGACGGGAGTTCCTCCGCTTT
CCGCCGCGCGGCTCGCGGTCTCAGCCGAGGTCATCGAGGGCCAGGAGCCCTGGCGGAGGCCCCGCCGTCCCGG
ACCCACCGACGCACTCCCAGGGCTTGGCGCTTTCCCACCACCCCGGACCGCCCTTGGGGTGCCGGAGGGGCTC
GGGGCGCGGCGTGGGGAGCCTTTGTGCCCTCTCCGCTTGTTGAGGTTTTTTCTCCGGAGGAGAGCTCCCCGCC
CGCCACCCCTTTCCTCTCGAAAGTTTTGTGGTTTCCCTAGAAGACGAAAGAGGTTGAGAAGGTTGCGGAGACT
TTTGCAATCTTCCCCGTCCAGAAACTCTAAAACCTCTCGGCGTTTGGCCCAGGGGAGCTATCTGGGGTCAAGG
GGAGGGAGCTGGCCGCACATTCCTTCGCCCGCCTTCCTCCCACCTGGAGCCGCGGCCCCGCGGGGCAGTGCGT
CCGAGCTGGTGCGGCGACGCCGGCAGCGGCGGGGTTAAGCTCAGGAATGCGGCGCGAGGAATGCGCATGCAGA
TGAGGCGGGCGGGCGCATGCTAATCGCATGCAAATGAGGGGCCCGCCGCTGCCGCGGCAGCGCCGCAGCTTCC
CGGATCCGAGCCCAGACGGCGGCGGCTCCGGCAGCCTGGGCGCCGCGACCCTCGGCGGCCAGAGGGGGACGGG
GCGGAGGAGGAGGAAGAGGCGGAGGCAGCGGCGGCGAGGGGGAGGAGGGTTCGCTCGCCGGCTCCGACGCAGA
CATGGTGGACTGATCCGCAGCGGGGCCGCGAACAGCGTTTCCTGAGGCACCTCCCGCGCGTGGTTCCGCCGCG
CCCCGCGCCCTGCGCCCCTCAGCCCCTCGCCGGCGCCCGCGTCGCGGGTTGGCAGCCTAGCCCGGCAGCCGCG
TTCCCGCCGCGTCCCGCGCCCGGTACCTATGGAGGCGCCGCTCGCCGGCGAGGCCGCCGACCATGCCTAGGAG
GGCCGGGAGCGGTCAGCTGCCGCTGCCCCGGGGCTGGGAGGAGGCCAGGGACTACGACGGCAAGGTCTTCTAC
ATTGACCACAACACCAGGAGGACCAGCTGGATCGACCCCCGGGACAGGTGGGCGCCGGCCGCGGGGGCGCGGG
CCCGTTCGGACACGGCGGCTGTTGTCCCGGAGACCCGGCCGCGCGGGGGGCTGGGGCGGCGCCGGCCCGCGGT
GCCCCGAGGGGTCCCGGGAGGGATGTGGGGCTGGCTGCTCCGGCGGGGCCGAGGAGCCGCCCGTACCCGGGCT
CCTCCGCCCACCGGCTTCCCGACGCCCCTCCGGGGACCCGGCCCCGAGGCAAGGCTGGAGTCGCTGCCCCGGG
CCGACGCCGCGCGCCAGGCTAACGGACCCGAGGGGCCACCTGAGCCCTGTTAGGAACTTCCCTAGGCTTCGAG
GTGCCCACGTGGAGGCTGCAGGACACCTTCGGCCTCTGGGCGGCGGGGGTGGGCTAGGGCCTCACTGCCAGTT
GGGGAACGAGCCCTCCGGGCCACCTGTGGCATCCCTCAGGCCGTCCTTGGCGCGGGAGCCTGGGCTGCGAGCT
CTTGGCGGGGGCGCCCAGACTGGCCGGAGGTCCCGAGCTGGGAAGGGGCTCCCGCCCCCCGCCGGGCCCTGCT
AGTGGGTGTGACTGACTTTGCCCCTCAGAGTTTAAAAACGCGCGTTTGGGGGTTTCGCTGTCTGTCG
CGI: 33 range = chr5: 360287-360592
CGTGCGCCTCAGAAGGGGCGTTAGGCAGAACGCGTGCCCATTCTCAGGTGTGCTCGGCGTGTGTGTGCTCGGC
GTGTGTGTGCTCGGCGTGTGTGTGCACACGTGTGCCGTGCGCCTCAGAAGGGGCGTTAGGCAGAACGCGTGCC
CATTCTCAGGTGTGCTCGGCGTGTGTGTGCTCGGCGTGTGTGTGCACACGTGTGCCGTGCGCCTCAGAAGGGG
CGTTAGGCAGAACGCGTGCCCATTCTCAGGTGCGCTCAGCGTGTGTGTGCTTGACGCGTGTGCACACACACAT
GTGACGGTGTGCCG
CGI: 18 range = chr5: 1161803-1162051
CGACCGGCGTGCACCGTCTCGCCATTCCCAAGGGCAGTGCAGAGCATGGCACCCAGCACCCGACAGGCGAGGA
CGGCCCAGGACAAAGCGGCAGCTCTAGCTGTCCTCAGATTTTGGGAGGGGGCTCCCAACACGGACACGGTAGG
TAGTTGGAGCAGGAGGGACGGGCAGGCCACTGACCACGCAACCGGGCCTCTGTCAGCGGCCAGGGGCAGAGGG
AGGCAGGACCGCCCCTGGACAACCGACACG
CGI: 584 range = chr5: 3647468-3656054
CGAGGCTCCGTGAAGAGAGGGAAGCGAGGCAGGGGGTGAAGGGACCGCCTGGCCGGTGTCCAGGATACGGGTG
GCTCAAACCACCAGCAGAACAGCATGCCGACTCTGGCCCGATGGCCGCCTTCATCCCGTAGCCCCAACCCGGC
CTAAAGCCGAGAAGACGCCAGAGTGCGCTGCTGAAATTCCCGCGGAGTCCGGTGTGCTGGAGAGCCGCAGCGG
GGTGAACTCCCGGCCCCGTCTCTGCGTAGGAGGTGGTTCGCAAAGTGGCCCCGGGAGCCGGGACTGGTACCCG
GTTCCCCACGGCACCGTCCGGAGCTCTCCAGCCACGAGGCGCAGAAGTGGCCTGCCAGCGCCTTCCCAGGCTC
AGGGAGGCGAGGAGGCCCGTGCACTTGGCATCTTCTCCCGGGAGCCGCACGGCCAGGGCCGCGGCGAAACGGA
GCCCATCTCAAGTGCGCCGCGCCTGGCCGCGTCCTGTAGCCCGACGAGGCTGAGGATGGAGAGGGGAGACGCA
GGGAGAAGAGGGACGCGGGACTTGGACCCAAGAGGCCGCTCCGTTGCCGGTCTGGCGGCGGCGCCGACTCGGG
TTCGCGCGTTCCACACAAGTTTCCTGTCTGCCTCTGCACACCTGGTGGACAAACCGGGCGTCCAGGCCACACC
GTCTTCCCCCTTCGCGGGGGCGCGGGGGATGTTTCCCTCCGGCTGCCAGGGGGCTTTCTGGGTGAAGAGAAAG
CCCCTCCCCCCGCGTCTCCCCCACCCCTCCCTCCGAGAACCCGCGGCGCCGACTGCGCCTGCTTCCCCCGAGC
TGGCGACTTCTCCGCGGGATTTGCCCTCGCTCAAAGTTTGCACAATTGAAAGAGCCCGCAGAGCTCGGCCGCT
CCCCGCTTCCCCAAGGGCGGCGAGGCCGGTCATTGGCAGACGATCGGTTACTACCCAGTAGGGGCCCACGGGA
ACCCGCATCTGGAGTCGGGGGTGTCACGCCACGCCGGTTCAGTGGCTCGCGGAGAGCGTCCGGGTGCACTTCT
GCCAAAGATGTCCCCTGGAGGCCCCGGCCGCGCGGGACTCGGGGGAGAGGCCGCTCCCCCCTCGCTGTCACCA
GCGTCCAGGCCGCCGGCCCCTTCCCCGCTGCCCAAACAGTAGAAAAGCAGGCGCCAAGTTGTTTTTGTTAAAA
AGGGGACACACCTCGGCCGCGAAACTGCAAACCCGGTGTCAGACAGCTGTAAACCCGTGTCGACAGGTTGTCA
GACAGCTGCGGGGGCTGGTCGGGAAGGAGCCCACGGCCTCCGGGCCCACACCCCGCCGCCCCGACGCGCGCGC
CCACCGCGAGAGTAGCTGGCCGGGCCGGCACGGGGCACCACGTGCTCGCGGGAGGGGCGGGAGCGGCCGGCGA
GGGCGGGCGGGAGGCAGGGAGGGGGCGGGAGGGGAGCCAGGGGCGGGGCCTGCGCTCAAGGGGATGCCAATCA
AAGCATCAACTTCAAATTGTGTCTGAAAGCCCCGCCGCCGAGCGGAGGGCGGCCGCCGCAGTCGGCGCGCGAT
TGCGGATCCGGGCGCAGCCGGGAGCCGGGCGCCTGCGAGCACCGGGCAGAGGAGCCGCGACCGGCCTCCATCT
CCCGGCCCGCCCGAGCGCGCCCGGCCGGCCGCCCGCTCCTCCCTAGACCCCTCGCGGCGCCCCCTGCAACCCC
CTCCGGCCGGCCTCCGCCTCCCTCCCCGCGCCTTTAATACTCGCCCGCTGCGGCGGTCGCCGAGTCCGCGGAC
ATGTCCTTCCCGCAGCTGGGCTACCCGCAGTACCTGAGCGCCGCGGGGCCGGGCGCCTACGGCGGCGAGCGCC
CGGGGGTGCTGGCCGCGGCCGCTGCGGCGGCTGCCGCCGCCTCGTCGGGCCGACCGGGGGCCGCGGAGCTGGG
CGGCGGGGCAGGCGCGGCTGCAGTCACCTCGGTGCTGGGCATGTACGCGGCGGCGGGGCCGTACGCGGGCGCG
CCCAACTACAGCGCCTTCCTGCCCTACGCCGCGGATCTCAGCCTCTTCTCGCAGATGGTGAGTGCGCCCGGCC
TCCCCCGCTTCTCCTCTGTCTCACCCGCGCCAGGGCAAGGGTGGCGGGTCGCCCGGGAGGGAGAGACTACGGG
TGGACCTGGTCCGGAAGAGGAACTAGAAAGGTCCGGGGGCAGGTTCCCGGTGGCCGAGGCCGCGGCCCCCGGG
GACGCAAGAGGGCTGGGAGGCCGGGCGGGTGACGGCTGGGCCATCTCGGCCTGGGAAAGCGGAAGGCCCGGGC
CAGGGAGCGGGTAGCGAGTGAATTCAGAGAGGCCGCAGAAGCAGGCCCGTGGAGCGGTGCCCGCGCTGGAGGT
CGGGGGCAAACTCGCCTGGCTCGGCCAGGGCGCCCGGGCAGGCCCACGGGGTTCCTGCAGGTCGGCCCGGCGT
AGCGTAGCAGGACTTCCCTTCCTGGCCGCGGGTTCCACTCGCGCGGCCTCTTTAGTTTTCGAACCGAGTCTGG
AAAACTTGGTTTTCTCCCTCTTTAGCAGCTCCGAGATAGTTGTATCCGAGTTTGCCAGACAGACCCCTTCTAA
GCCTGGTAGAGTCAATCAAAATAATCTTAACAATAGAGGTCCAAAGGGATGGAGAGGTCTCTCCACGGCGTGA
GTGCGAATTTGAGATTAAACAAAAATTAAGTTGCAGTAATGTGCTGGTGTCTGAAACGGTGTTTGATTTTACT
TTTGTAAGTTGCCCAAGTTTTCATTTCATTTGCACAGAAAGAAAAGCACTTTTCTTCCTGCGTTACATAATGG
AGGATTAAAGAAAACAGTGTCCCTTGGCTTAAAACAAATGGTGTCCTCTTAGTCTCCCGTCCCAGTGGGCGTT
AGATGTCGGGGCAGGCGGCTGCACACTTAATTCTCCGCGGGGGCATTGGCCTGTCTGCCGGTCCAAATCATCC
ATTTTCCTTGGTCTGACTGCAAGGTCGGTGCTTAAACTTCGGACGGCTGGTGAATTGTGCGGCGGGCGCGGGG
CCCTGGGAGGCAGCCCCCTCCTGGGTCGCTGCCCGCGGGATAAAGCAATTTCCAAGCACCCGCGATATCTCCC
CGCTCCCCGCAGGAGAAGCGGGGAGTAAACGCCCCTCAAGTGTGCACAAGCAAAGAGCGGGTTTCCCTGTAAC
TTTTCTTGTAGTTTTGAAAGAAAGCGGCCCGGCTGCCTTTCAGGTCTCTTACTATCGAAAAAGATCAGCCCCC
ATTTTGTTCAGGCGGCGGGGAGGCCGGGACGCGATGAGAGATTTACAAGGTGTCCTTTCAAAAAGAATTCCCA
GTGGAGACGAGGCTGAAACGTCTTCTTTACAATTACAACCAAAATAATTAGAAAAGCGCAAAGTACATTTTGG
AACGATTGGGCAAAAACGAAATCTAGCCGCAGAAATGTTTTCTCTGCGGCCTCAGTCACCAAACTAATTAGTC
CAAGAAATCTTCTGGTCTTTACAACTTTCTCAGAGTCCGGAACTCCCTTTGCTAACATTGCAACTAGACCATT
TTTTCAGAGGATGAATATTTTTTACAGAAATTGCGAATGCAGTTGTGTGCCATTTGGGAACCCTGCCTGTGTT
TGCGGGGGAGGGAGAGAGCTTCAGTGTGAGGACCTGCACCCTTTGTGGAGAGCTGGGGAAGGGAGATGTTTGC
TGTTCTGAGTTGTTTTTCCCACCTAGAGGGATAATATGTAAAAATTATTCCCACCCAAAAGGTGTGTGTTTCT
CCAGCTCTCCCACTGGTTCTGAGAGAGTAAACTCAAACCCAAACCCTGATTCTAGGCCTAGGTTTCCAAGCCA
TTATAATTGGGTGTTTGGAAGTCAAAAGATAAAATTGTATTTGAATGTCTGTCTGCGCAATTTATGGTAATAA
TGAGGCCTAATGAGGTTGTTAGAAAGATAAAATGTTATTTACCAAAAAACCTGATGGGATAATTTGACTTGCT
GTGTTTTACTACTGATTATAAAAAGAATATCGATTGCAAATAAATCAGCGCCTCTAAATGCCTGCAAACAGCT
AGTGTTTGCTCCCTCCAGATCAAAGTCAAACTTAAGAGATGAAGTAACTGAGAAGAGGCCTAGGATACTGAAC
CGGTTCCCCTCCTGGCCGCCGGTGGCTCCCAGCCCTTGCGTTAATATTTTACAGGCTAAGCCTTCCTTTTGTA
TTAAAAAAAAAAATGGTGTTTTTGTTATTGTTGTCGATGATGGCCGGGATTAAAATTTTAAATTACCTGTCAC
CTCTAAAGACCTTTTAATGTGGGTAAACCATTATATGCAGATTAATTTGGAAGGCAAAGGACTGTGCTTTCGT
TTTAAATTGCTGGCGGATTTAGACCGGTAGAAAACCCGGGATGGTTTATTTTGATTGAGCCCCCTCTGGGTGG
CAGAGAGGAGGCTTGGGCTCTGGGCCCTTTACGTTTGGAGAAATGGCTTTATCAGCTCAGTTGAAAGGTTTTT
CCCTCTAGCTAGTGAAAGATAAACTTGGAAATGCAGGTTTCTCCAGCGGTTGGTGGTGGGGACAGGGGTCGCC
TAGGGAACTTGCAGGGGCCGCGGCCTCTGTTGTGCTCTTCTGGAGAGTGCACTGTTTGTGGAACTTTTCTAGA
GTGGCAAAAACGATCTCCACTGTCGGTGAAAGGGCAGTTCCTGAAGTCAGCTCATGGTCCTGGCTCCCCTTCT
CCCCAGCAGTGAACTGGGGGTGACTTCCTGATCTGCCCAGCACAGGAGAGCCCCGCAAAGCGCCTGGGAGGCC
CTCGAGTCCATTGAAGCGGCTGCTTCCCACTCTCCCGTCTTGGGGACTCATGTCTCTCTCTCTCTCTCCCTTT
CTCTCTCCACTTCCCTCCTCTCTCTCCTCGATGGATCTGCCCTGTGGCTTCAGGGCTCGCAGTATGAACTGAA
GGACAACCCTGGGGTGCACCCCGCCACCTTCGCAGCCCACACGGCGCCGGCTTATTACCCCTACGGCCAGTTC
CAATACGGGGACCCCGGGCGGCCCAAGAACGCCACCCGCGAGAGCACCAGCACGCTCAAGGCCTGGCTCAACG
AGCACCGCAAGAATCCCTACCCCACCAAGGGCGAGAAGATCATGCTGGCCATCATCACCAAGATGACCCTCAC
GCAGGTCTCCACCTGGTTCGCCAACGCGCGCCGGCGCCTCAAGAAGGAGAACAAGGTGACATGGGGAGCGCGC
AGCAAGGACCAGGAAGATGGAGCGCTCTTCGGCAGCGACACCGAGGGCGACCCGGAGAAGGCCGAGGACGACG
AGGAGATCGACCTGGAAAGCATCGACATTGACAAGATCGACGAGCACGATGGCGACCAGAGCAACGAGGATGA
CGAGGACAAGGCCGAGGCTCCGCACGCGCCCGCAGCCCCTTCTGCTCTTGCCCGGGACCAAGGCTCGCCGCTG
GCAGCAGCCGACGTTCTCAAGCCCCAGGACTCGCCCTTGGGCCTGGCAAAGGAGGCCCCAGAGCCGGGCAGCA
CGCGCCTGCTGAGCCCCGGCGCTGCAGCGGGCGGCCTGCAGGGTGCGCCGCACGGCAAGCCCAAGATCTGGTC
GCTGGCGGAGACAGCCACGAGCCCCGACGGTGCGCCCAAGGCTTCGCCACCACCACCCGCGGGCCACCCCGGC
GCGCACGGGCCCTCCGCCGGGGCGCCGCTGCAACACCCCGCCTTCCTGCCTAGCCACGGACTGTACACCTGCC
ACATCGGCAAGTTCTCCAACTGGACCAACAGCGCATTCCTCGCACAGGGCTCCCTGCTCAACATGCGCTCCTT
CCTGGGCGTTGGCGCTCCCCACGCCGCGCCCCATGGCCCTCACCTTCCTGCACCTCCACCACCGCAGCCGCCG
GTCGCTATTGCCCCGGGGGCACTCAATGGAGACAAGGCCTCGGTCCGCAGCAGCCCCACGCTCCCAGGTACAG
CTCCAGGCCGCGTCCACCTGTCCCCTAGCTGGGAATGCAGAGGCCTGGCTAGGTGTGGTAGCGTGGGGTGCAG
CATGAGCCGGGAGGGTACCAGGCAGTGGCCGCTGAGCCCTGGGGCTGCGCTTAATCCCTGCTTCAATTTAGAA
AGCCAGACAAGGCCCTAGGGCTCTCCCAAGAGAGCTTTGCCCTACCGGCGGGCCTGCTACGGGGTGGTGGTGG
GGTGAGGGGTGACGTTTTTCGGCGAATCTGCCTGGGCAGCCGGCAGAAGTTGGTGGGAAGGAGGCCTGGGACC
TCTCCCGCCCGTCTCTCCGTCCTAACTCTGCCTCTTCCGATCTCTCGCAGAGAGAGACCTCGTCCCCAGGCCA
GATTCGCCGGCACAGCAGTTAAAGTCGCCCTTCCAGCCGGTACGCGACAAGTGAGTGCTGTTTGCTTTTGCTA
TGGGAGAAGGCGGTGGGGAGGGGGGAGGAGGAGTGGTCGGGACCCGGGCGGAGCTGGCTGGGTGGCGGTGGGG
GTCGCGCAGTCCTAGTTGAAGGAGCGCTCCCCGCCAGCCCTGGGCGCCGGGCGAGCCGAGGAGACTGGAGTTT
CTCCCCAGCCGGGAGCCGCGCTGGCTGTCGACCCCGCCCCCAGGGCTCCGCTACTGGAACCGGCGTCGCCCGG
CGCTGCGTCCCCCACTCACAGTGCCCCTGTCTTCTTGTCTCGCTGTGTTTCCCATGCAGCTCTCTGGCCCCGC
AGGAGGGAACGCCGCGGATCCTAGCAGCCCTCCCGTCCGCCTGATTAAGGGTCTTCTTTTACTTTTGCGGGGG
GGAGGGGGGAGGAGTTGGGGAGGGAGGGAATGTGGGAGGAATTAAGACAAATATTTCAGACTGGTGTAAAGGA
CAAATATGACAACGACGTCAAGGACTCGCATCCGTCGCTTTCTGCAGAAAGGGGCTTCTTCGGTCCCGAGCTC
GCGTCCAGGTGGCCAGGCCTCTGCCGGCGGCTCCAGTGGCTGCGATTATCGGGTTCGGTAAATGCCCCCACGT
GCTTGTGTCTCTTTCCCCCCTTTTCTGTATATAGAGTGGTTTCAGATTGTAAATAGCGCGTCAGCGAACTTGT
CTAAATCATATATTTTTGTCTAATAAACTAAATGAAATGACACCCCCTCCCCGCTCCTGCTGCTGTGTGCCTG
TCCAGCGTGTGTGTGAGTGTGTGTTTGTGTGTGAATGTGTGTGTGTGAGTGTCTGTGTGGCAGAAACAGAGAC
AGAGAGAGAGAAGTGGGGGATACAGGGATCCTGGAACCCTGGGTGGGACCCAAGGGTCTGTGGCTGGGGGAGA
TGGGCTTCTCAATGGGGGCCTTTAGAGACTGTTGCCACCCAAGACGCAGGTGCTTTAAACATCTCTTCGTTGT
TTGTGGTTGTTGTTGAATTTTTAAATATTGTCACTGTGGCAGTTTCTTGCTGGCAGTTCAATTGCTTTCACGA
ACATTTTTCTGAGACATAATTTTCTCAGGACATAAATAAGTTCAATTTGAGGCAGTTTTACAAAACGATTTTA
TAACGTCGGTAAAAACAGAGGAAAAAGAATTTTTATTGCGACCCCAGAGGAGAACTTCGGATTAGAAACCAGT
TTACAACTAGTTGTCTCAACGGCGCATCGTGGCGCCTGGTCGTTTTCTGAGTTGAGTGTGAAAATAATGGAGT
ATCGCTTTGCATGTATTTTTAGTGATTCGGTTAAATCAAACACGGGAAGAAATTGGAAGGCTCTTTAAAACTC
CACAGATGGGCCAGCCGGGATGCGGTGCGGGGCTTCTCTGCGGTGTGAGGTGTGAACGAGGGGCTGAGGCTGT
GGTGGGAAGCGAGAAAGAGGAGGTGGCTTTGGTCTCCCAGGGAAGCCCCTTTACACTTGGGCTCCACGGACTG
CGTCCTTTGCCCTCAGGCGCGCGCACCGCGGGAGTCCAGAGCAAATTGCCCTTAGATGGCCGCGGCCGGGCAG
CGGGGAGGCAGCTGGGAGCAGCGATGTTGGGAAACACTCGCAGCGGGGCTGGCCTCGGGCGCGCGCGAGTGGG
GAAAGGCCTAGGAGCCTGGACATCGCTGCGGATCCGGGACATCAGCATCAGTGGGTTCGGAGCGGGACGCGCG
CCACGCGCCGCAGCAGGCACCTTCAGGAGGCTTTGCGGACCCGGCGCGGGGCCTTCAGGGCGCAGGCGACTCA
GCGTTGAATGCGTGAAAACTGAGCCAGCAAACATTTCCAAAACTGCCAGCGAGGATGTGGGCTGCCGGGAAAA
ACGGTCTAGTGGGGACAGGGCCGAGTCCCGAAGTCAGAGCCGAGTCCCGAGGTCAGAGCGGCCGTCCTCCGCT
CGCACCCCCAGCCTGTGACCCGCCCTTCCCGGCTTGCTCGAGACCCACTGGCGCCAGTGCTGCGCGTGGGGAC
TCCGTGCATGGCCGAAGCGAGGGGGAAAGTCGGGGCGCTGGTGTCTTTTCAGAGGTTCCAGGAAAGAGGGAGG
CTCGCGTTAGGACTAGGAGGTGCCAGTCCACGGCTCCTACCCGCTCCCGACGCCCGCATCCTTCTACAGCCCT
CCACCCCGTTCCTGGTCCCTGTAGAGGGGAAGGTCCTCTCCCTGCCCCGAGGCGGGAGGAAAAGCGGCGAAGA
GGAGGCTCGAAGGGCGCCGCGTAGGGCAAGTGGGCCGAGGACACCG
CGI: 140 range = chr5: 5192442-5193941
CGTGTACTCGCGCACACGCAGTCAGGTGTGGATGTACACCCGCGCACACCCAGGCACATGTACACCCGCGCGC
TCACACACCCCATCCAGCTACAGCAGAATTCTGGCCAGGCTGTTGACCGCACACCTGCTGCCTCCTTGGCCAC
CCTGTCCACACAGTAGCCCGATCGACCCCCGTGGCGGCCGAGACCCAGGCCCATCCGCAGCCCTGAGACCTCC
CTAGGGATTGCACCCAGCAGCCAGTCACCGGCCTCCGCGGCCTGGCCAGTTGAGGGTGGCCGTGACCGCGGGG
CCAGGAGCGCCGCCACATCTCGGGGCAAATGGCGCGGGGGAAGAGTTTCCTCCTCAGCCTCCCCGTCTCCGAT
CGCTCCGCAAACTCCAGAGCGAGGCACGCGCCTTTAAAGGCAGGTCCGCGGCTCTCCCACGTCCTGGCGCCCG
GTTTTCCGCACCCAGTGTCCCCACAGCTGTGCCCGGGCACAGAGGCGCGGCCAGACCGCACTCCGCGGGCTGC
AGGTGTCCCGGCCTCTGGCGGCGCCGGTGCGGCCCGGAGGTGGGAGCCCGCGGAGCCACTGCAGTAGCTGGAG
TCCCGCCGAGTCCCCAGCCCCAAGGCAGGGCAGGAGCGCGCACCGGCCGGAGGTCCATGCTGAGCATCGCCCG
CGCCGGTGCCCGGCAGCCTCTCCAACTGTGTGGTCCCCGCGCGGGCAGAGAGGCACGGACTGCAGGCCGTGGG
CAGCTCCATCTTCCCGCGTCCTCCTCCTCTGGCGCTGCCCGCTGTCTCCCGCCTTCCCTCTGCTCCCCGCTCG
CCTCCGCCTCAGCGCCCCGCTGACCTCGCCTCCTCCCCTCTGCTCTTTGTCCCTGCACTCTCCCCTCCTCGGT
CCTCTGACCCCCCCGCCCTCACCTCCTCCCCTCCTCTCTCCCCTGCCCGCCCCGCGCTCTCCCACCGCTCCCG
CCGCCCCCGCCGCCGCGGCTGCCACTCCGCCCCCCGCGCCGCACGGAGCTTCAGTAATAACCCCGGCGCGGCG
GCGGAGTCGCTGTGGGGAATCCTCCCGCGCTCTGCCTGGGTCGGGTCCTCCCTGCCCGCTCGCACGCTGCCGG
CCGGGGACCCTCCGGTGGCCCCTAGCCCCTCGGAGCGCTCCTGGATGAAGCCCCGCGCGCGCGGATGGCGGGG
CTTGGCGGCGCTGTGGATGCTGTTGGCGCAGGTGGCCGAGCAGGTGAGTCCCGGGCGCTCCCACCAGCGCGGA
AACCGCGGGTCCGGACAGCTGGAGGCGAGTCCCCCGCGGCTCCTCTCCCGCGGACCCCGCCGTCTCACCGCGA
TGTCGCCGCTGTTTTCCGCAGGCACCTGCGTGCGCCATGGGACCCGCAGCGGCAGCGCCTGGGAGCCCGAGCG
TCCCGCGTCCTCCTCCACCCGCGGAGCGGCCGGGCTGGATGGAAAAGGGCGGTAAGTCCGTGAGGTGGGGGCT
TCTAATCCTTGCCATTTAGCAGCTCGTAATCTCCGTGCCG
CGI: 21 range = chr5: 6790705-6791004
CGGATCGAAACTGTGGTGAAAGACCTTTGGCCGACGGCTGATGTGAGTATGTTCTTTGGAGTTCTGTGTCGCA
CGTCACGTGCGAGTAAATTTAAATACCCTGTGATGATGATGTGTCGGCTAGATCCACACAGACCTTTTCTCGT
TGGCCCGAGGCAGCAGTTCTCCAAGTGTGCTTTGAGAAGGCCTCCGTTGCCTGGAATGCATGGCCCCCGGCGC
ACCTGCACCTGCTGTCTTAGACACCTGCGGTGGCCGCACATCTTCGTGATGCTGGCGCGCACTCAAGTGCGAA
GACCATCG
CGI: 54 range = chr5: 54554812-54555385
CGGGCTCGGCGGCGGTCTGCTCGCACTTACGTCGCCAGCCCAGTCTCGTACCCGAAAATTCAAGCCCCATCCG
AGACAGGGAACCCAGCAGGCTTGCACTGCCACGGTGGGGAGCGGGACGCACGGAGCACGACACTGACTGGGGG
AAGGGGGCAGCAGTTCGCGGCTCCTGCAGAGCAGCTGCGTGGCGGGAATGGGTCCTTCCACCGGCGGTGCGGC
GGCCCTGCGCCGGCTCCGGGCAGCCGAGTAGCCCGCCACCCACCAACTAGCTAAGCAGCCGCCTCTGTGAAGC
TCGGCGGTTCCCTGTGCGCCTGCGAAATTTTGACTCCGACTCACCAGCGACCGGCCACCGAGCCGCCGCTGTA
GGAGCTGAGAGCACGTCTTGAACACCGGATCTTTCCACCCAAGACCCGACAGCGTGCAGGGGCCTCGAGCAGT
AATTTGAGGCCGCGTTTCCCGCCAAGGTTTGGCCCCAGCTAACCGCCCCACCCATGCAACCGAGCGGGAAGAA
AGCTGTGATTCGAGGGGCCAGGAGAATACGGGAAAAGCTTCTGTTCTGCGCACAGCCAGTGCG
CGI: 129 range = chr5: 114542616-114544119
CGCGCACAGGGAGTCGAGTGCTCCTTTGTGCCATCACCTCTTCTCGAAGCTCCAGGCGCAGAGGGCAAACGCT
GACGCCCTTTCCCGCCTTCTCTCCGTCTGCGAGTTCCGGAGGGCAGTGCACTGTGCAGCCTCCGTACTTCCCG
ACACGTTCCGCCTGCAAACCACTTAGGAGCTTCTGCCGGCAATTTCTCGGATGCAGCGCGGAGCCCAGCCTCC
CGCACTGACTCAGGCCCGGCACCACCCCGCCTGCTGAGGGCGTCGTCGCGGGCGCCACCGACGGCGCCAGCCT
GCGTTCCTAAAGGCTCCAGGACAGGTGTGGGGCTGAAATCCCGCTCCTCCAGCATCTTCCCCTCCCTACCAAA
AGAAGGCTGCTTTAAATATTCCCGGCCTGGAGCAGCAGCAGCTAAGGACCTGGAAAGAGGCCCGAAAAGGCCA
GGGCAGGGCGAACGAACGTGCTGTCCCTATTTACCGGCCACACGCTCTGACTGCGGGCTGACCCTGATCGCAC
ACTTCGAGCCTGTTCACTCGCTGGGCGGACCCTCCCTCCACGCTCCGCGCCCAGGCAGGCGAGGTCACCCACT
CGAAGTCACCACGTTTGAGTAGCCCTGGTTGGTGGGGCAGCGCCCCCTTGGCCAACGCCCCGCCCTCCTCTCC
ATCTTCCGACGCTGGGCTCTCGCCCTTCGGCGTCCGAGAGCCCCTATTGCTGCCCAGCTGGCCCCAAAAGCGT
CCGAAAGTCCCCTCTTGGCTTATTTCAGAGATGCCACGCAATAAAGAAAAGGCGGCTACTTTGCATTCCGCAG
CTGCTGGGACGCCCGGGCTGCGAGCGCGGCTCCTGGATTCCAGCCTCCCGCCCTTCCCAGGCGCTGGAATGGA
CACGGACGCCCACAGTGGCGGGCCAGGTAGTGCCGGAGTCGGGGGCCCAGGCCGCGGCGCCCCGCGCCTCATC
ACTTACCTTGCCTTTAGCTATCAATTCCATGATGTAGCCAAATTCACTCATCTCCCCAGACTCCGACATGTTT
ACACCCCTTCACAAACTCTGGAGGACCGACGCGGGTGTATCGAATTTGTCCTTTCTTTTCTCTTTTTCTGTTT
TTAGTCTGAGTTTTGCCGAGCTCCCCGCCCATAAGCTGTTAACCAGGAAAAGAGGGGAAGCGCCGGGGAAAGC
AAGAAGCGGGCTTGGGTGAAATGAAGGCCATCGAGGGCTCCCGGGCAGCCTCGCCCGGCTTGCTAGGATCCGG
GTGCAGCGGTCGGGGCTGCGCGATCTAACGGAACAAACGAGGGCGGCGGCGGCGGCAGCAGAGGCCGTGAAAC
CCTCACCAGGCGGAGCCGGGCGCGCGGAGGCCCCGCCTCCTCGGGGGTCGCGGCAGCGGTTCGGACCGCAGCG
GAGACAAACAAACGCGCACACAAAGCGGGTCCGCACTCGGCTCAGCGCGGCCCCAGCTAGACATTCCCCGGCC
TTTATCGCATGCCGGCAGGTTGGCCGTCCCCGGCTCTCGGCGCG
CGI: 21 range = chr5: 127899858-127900162
CGCGTCCCGATTATCAGTGCAATGTGATCACTTGATTTTAAACGCAACTATGCGTCCAAATGGCTGAGTGCAA
GAGGTCGGCCGGAGATAGGGCCGAGTGCGCTGCCCCAAGCTGCGATCCCTGCCAAGCACTCACGGACAATGCA
CTGGTTTCCTCCAGGGAGCGTCTTCCATCCAGGGCAGCAGTAGGAGTGGAATCTGGAGCCGCACACGTTGGGC
CTGTGATGGACAAGCGCGGTCACGTAACAGATAGGTAGAGGGATGCAGCAACATATAAACGGTCTTCGTAAGC
AATGCCCCGAGCG
CGI: 56 range = chr5: 135720297-135720941
CGCCAGTCCTTTGTAGGCGTTCATGCGCGAGCGCGAGTGGCTGAAGGAGTCTTTCCGCTGTTTCTCGGTGCAC
TCATTGCACTTGCAGAAGTAGTCGTGGGGCCGCTCGATGCGGGCGCCCTTGAGCAGCAGGATGTGCACGATCT
CATACTCCTGGCAGTGCGCCGCCAGGATGATGGGCGTGATGTCGTGGGAGAAGCGCGTGCCGTCCTCGTCGTA
GGCATAGAAGTCGTCGTCGCGCAGCTCCTGTTCCAGCGGGCTGAGCGTCAGGCGCTGGCCCTGCGCGAAGGCC
GGGTGGTTGAGGATGGCCTCCACGATGCGCACATAGCCCTTGCTGATGGCCAGCAGCAGCGCGTCCCCCACCC
GTGCCAGGTTCTCCTTCTTCAGCAGCAGCTCCGTGACCTCTAGGTGCTCGTTGCCCACGGCCAGCTGCAGAGC
GTTCTGCCCCATGTAGTCCACACAGTTGAAGTTAAGGGTCTTGGACTCCTCCAGCATTTTCCGGACCACCGGG
ATGTTGCCATACTCAGCCGAGTCCAGGAAGCGCTCCTCCTCGGGCGTCAGACTGGTGCCCTTCTCGTTGAACA
TGTAGGCGGGACCCCGGATGGCCTGGCGACGGCCCTTCTCCCTCAGCGTTGTGTGCCGGCG
CGI: 29 range = chr5: 140780945-140781256
CGAGAAACCGCGGAATATCGGCTTAGAGCCTGCCATGGCGAATCGGCTACAGCGCGGGGACCGCAGTCGGCTG
CTGCTGCTGCTGTGCATTTTCCTGGGGACGCTGCGGGGGTTCCGGGCCAGGCAGATCCGATATTCGGTGCCAG
AAGAGACCGAAAAGGGCTCCTTCGTGGGCAATATCTCCAAGGACCTGGGGCTGGAGCCCCGGGAGCTGGCGAA
GCGCGGAGTCCGCATCGTCTCCAGAGGGAAGACACAGCTTTTCGCTGTGAATCCGCGAAGCGGCAGCTTGATC
ACGGCAGGCAGGATAGACCG
CGI: 182 range = chr5: 141235749-141238152
CGCGGCGTCTTCCTGCACGAAGCGACCCAAGCAGCCCCAGTCCGCACCGCCTTGGTCAGCGGGCGCTCCCAGC
ACACACCCAGCGCGCGGAGCGACTCCTCCCAGAGGACGCCGAGTGTGTGTGTGTGTTGCGGAGATTAGGGGGT
GGCGGGGGGGACGGCGGCAGTTTCTTGGGCTCTGGCGGCCCCACCCCCACCCCGGCAGCGCCCAGCCTCCAGG
AACCCAAGGCAAGGCTAGGGCGCGGCGTGGTGAGAACGCGCTTCGGCTAGTGGGGGGAGCCCTTGCGCCCCCC
GCACCCAGGCCACCGCGGGGAATCCCTCCTCCCCGGCATCTCCGGCCTCGGCCTAGGGTCCCCCGCAAGCCGG
AGCCGGCGCGAGCGGCGCAGCGGGCGCCAGGAGGGGGCGGGGAGGGAGCCGGCGCCGGAATCACAAAGCCGCG
AACCCGGCTAGGCGGGGACATTCTCATAAAACCGACCCTCTCGTGGCGAGCAGAGGGGGTTTTTTGCCCTACG
CTCAATCCTCCAAGGCCTCAGTGCCGCCCCCAGTCTTTCCTGGCAGAAGAAATAGTAGCCGACCACTGTTGGG
GAAACTGAGGCCAGAATTCTGACTTACAGAGGGTAGCTGGGGGGAAGGGGTGCGAGACCACCTCGCCTACAAA
TTCTGCTCCTATGCCTGCCGCGATCTCCGTTCTGGCTCCAGGGCCTGCCCGCGCACACACTGGCCTACAGCGG
GGACCAGGCGGAGGGGGCGCTCAGGTGTGAGACGAACCCAGGTGTGCGGGACCCACCAAGGTGTGTGGGACCC
AGGTGTGCTGGAGACCCAGGTGGCTCAGAAAACTCAGCTAAATGGCTGGAAGAGGGTCGCAATCACCGTCCCA
GGCTAGCACCCTCTACAAAGGAACCTGGGGCCCCAGAGCTCCGGGGAGGCGGGATGGCTTGGCCAGCCAGGTC
CAGCTTGTTCCCGGAACACCAGCCGGTTCGGCCCGGGAGTGGGGGTTGGGGAGGCGCCGACTGGGAAGCCGGC
AGGCCGGCCCAGCCTTCCCGCTGTGCCGATATTTACAATAATAATGTCGCGATTAACGTGGCGGGGCGCTTGG
GGCTCGCCGAACGACCCCGGCGGCTTCTCCTGCCTGAATCTGGACTCCGAGAGAGAGGAACGGAGTGTGTGTG
TTTGTGTGTATGCGCTGCAGGGTGTAATGTAATGTGACACTGTTGGTTTAAGGTGTGTGTGACACCCAGTGTT
AAGATGGGTGAAGCAGTGGATTCTGTGTTTGTGACCGTGAGGCGCTGCTGTAGGTGCCAATTCCTGTGTTAGA
GTGTGTGCCATCAAGCGTGTGCTGAGATACTGGGTTGTGTGTTTGTGTGGGTGCAGTAGAGGGGTGCAAGGAG
ACCTGTGCTGTGTACCTATGTTCTGGCCAAGAAGTGGGTAAGATGATATATGCTAGGGTGTGTTCCTTAAAGG
AATGTGGGGGGTGGCTAGGTTTTGAGGGTTCATCTAGTGAACTGTGGCTGTGACACTCGTACATGAGGGCACG
AGATTGTGTTTGTGTGTCCACGTCGCGGGGTGTCACACCCGGTTGTGTTATTGCTCTGTAAAGCCACGGGTTG
TGTGTCGGTGCTGCTGATCGTGCAGACACTGAAGCGGATTCTGAGCTGGCGACGGTGCCCCAGTGGGCGCTGG
TGTGCGGGAGGTATGTCTGTGTGCACATATGCAGGGATGTATGTATGTGTGTATATATGTCCACGGTCTGGCC
CTCTGGGTGCCCGCGAGAAGCTGGAAGCGGCTGAGTGAGCCGAGGTAGTTGCCCAACAAGTGTGTATGTATGT
GTTGTGGACAACGGTCCTTGCTTGCTCCGTCCTCCGGGAGACCCCCACCAAACTGGGGGCCGCGCGCTTCCCC
AAACCCATCCTCCACGCCGCGCGCTCCTGGAGTCTCCTTATCCCCGTCTCTCCGAGCGCGCCCAGGTTTGGGA
CGCGGGGACTAGGGTTCTGCTCAGCACCCCCTCCCCTCCCTCGGCTTCTCGCCGCGGACCTGGGAGGACGGAA
TCCCTCAGCCGCATCCCCTGCTATGGGCTCCCAGCAGCCCCCACCTCAGCCCCCTCGCGCCGAGCTCGTGTTG
GGCCCCCGCGGCCTCGCTCCGCCGAGCGCCCCTCCCTCAGCTCCCGCCGGCCATGACCGCTTCGGGCCCCAAG
CCGCTGCTGCCTCCACCGCCGCCGGATCCTTACCCGCCTCCGGGCAGCGCCGGCCGCCCGCCCCGCTGTCCAT
GAGCCGCCGCCGGCCCCGGCCTGGGCTGCGGCTCCGCACGGCTGGGGCTGGAGCTGCAGTTCGGGCTCCGGCT
CCGGCTCCGGCTGGCTCTGGGCGCAGCAGCCCGGCGGCTTTGCGTCCGCGCCGCGCTCCCGCTCCCCG
CGI: 263 range = chr6: 1326743-1330210
CGCCGCGCAGAGTCGGCCGAATCCAGCTTCTCCAAGGGCGGGCGGGTGGGATGATTTGTTGATTTGCTTGTTT
TCCACCAAACCGCAGGGCACCTCCAGGAGCTCCGGGACAACTTACAAATGAAGACACAGAGCCCCCGTCCCTT
GCTTCAGAGAACCAAATAACGGAACTGAATGATCGTTTCTTCAGCAAAGCCTAAAGACGCTTGCGTCCCGCGG
AGAGGTGCCCACGCGCGACTCGGCTGCCCCCTCTTCTTGCGGGTCCGGGTAGGGTAGGGCGGGAACGCGGGAC
GTGCCCTAAGCGGGCCAGCCGAGCGCGAGACAGGCGATGCTGCAGAAGCCTGCCCGCCTGCGGGTCACACACC
GGCCGGCCTCGGCTGCAGGGGTTGCGGGGCCACGGGTCGCGGGGCGCCGGGAGCCGCGAGCAGGTGACGGCCG
CGCCGGGCAGCCCCGCGGGCCGCGATTCCCGAGAGCCTGGCGCCACCCCGCGGAAGCCGGAGGAACTGCGGCT
TCTTCCCGCTCCCGCGCGGAGGGGAGAGGGAGGCGCAGCGCGGAGGGGAGAGGGAGGCGCAGCGCGGAGGGGA
GAGGGAGGCGCAGCGCGGAGGGGAGAGGGAGGCGCAGCCCGCACCGCGCAATCCCGGGGCTCTGGCGGGAGGG
AAGGTGACTTGCGTGGGACGACTCCAAGAGGCCAGGCCCGGCCTTCGCAGTTCACCCACGAGGATACCGCGAC
CAAGCCACCAAAGCACTCTCTGGCCAGGCCGAGACCCCTTTTCCCCCGGGCCCCAAGAGAAAAAAGCACTTTC
TCCTAAAACACGAACTCCCCGCGGAGGGGCCCGGGGCTGCCTGGCACGGGGCAGGGTGTGCGGCTGCCGTGCG
GGCGCGGGCCAGAGTCACGTGGAGGCAGGCGGAGAGGGCGAGGGGGCCCCCGTAAATCATCCTGAGGGATTTT
TGGCCCAAGTCCCTGTTTCCGAAAGGTTGCGGGACGGCTTTGACGTTGATTATGTAGCTGTTCTCTTTTCAAG
TGCGCGCCCCTCCCCACCGCAGCCCGTCTGGTGTGCGAGGATTGTGTTTGAAAGGGAGGAAGCATCCTTGAAG
TGGTGGGTGATGGATTGTCTAAACCCTTCTGGGACGTTCTGGGTGGGGGTTTTCGAGGCAGCTCATCAATAAA
GACCCCCCTGGAGAGAAGGGGCGGCTGGAGACCAGCCCCCGCCGCGCAGCCCCGAGGCCCCAGGCCTGGAACA
CAGTCCTCGGTGTGGGGCACAGGGCGTGAGGGGAGGATGAGCTCCCCCTGAGCAGATGGAGATTTCTCCTTGC
CTGGGCCGTTTGACCCCCAAAGCCTTGCAGACTGGCCGCGTGGGTGCCATGGGGCGATTTCTTGGGAAAGGAG
GGCAGCAGAAAGGCCCGTGGGCTCTCAGCGCCTTGGAGTCAGGGGAGCAGGAAGGGGAGTGGAGGTGCGGACA
CGCCTCCAGCCACCGTGCTCCCCTAGGAGGATCTCCCTTCAGCCCCTGTAGAACCCTGCATCTCAACCACCCT
CGTGCATGTGGTTTACCTTGGCATAGATTTCCAAGCCGCTACAGAAAACCTGTCCACCTCCCCCAAGGTGGAG
GCGGGAGTTGGGAGGCAGGGGTGCTGGAAAGGGTCACCTGGCTCAAGCCGACCCCAGGTCTGACGGGCGGAGA
GCCTCGAGGGCCACGCCCCAGGCCAGTGGTGTCCTCTGAGGCCGCAAAGCCGACTGGCTTCTGGAGGAGCAGC
AGCCTCGGCCTCAGCCTCGGCTGGGAAAAGACGCAGTCGGGGCCCTCCGTGCTCCAAACTTGAACTACTCTGG
GTCCCCACGAGGAGGAGGCTGCCCTGGGGTCAGAAACTCCGACGGAAATGAAGGGGAGGGGGCGTAGGTTCCC
TGGCACAGCTCGGCCTGGAGAGGCAGCCTGGGGGCCCAAACTCATCTAGGGCGCGCCCGGAGCTTCCCCGGCC
TCTCTTGGCCCATCGCGAACGAGCTCCCCTCCCCGACTGGGTCGGCCTCGGGCGCCTTTCGCCTTCGCAGGCC
GCCGGGGTTCCGCGGAGGGCTTGTGTCCCTCCCTCCCGCCGCCGCAGCCCGCCCGAAGGTCAGGCCGCATCCG
GGGCCCGGGGCCTTTGGCCAGGCTGCGGGGAGGGGTGGGGTTGGGGGGCTCCCCAAAGCAGCTTCTCGGAGGC
GGCGTCGGGGCGCCCTGAGGTCCCTAGTCGGCCTCTGGGCGCCGAGCACGTTTTATTTATCCCCACAGAGGAT
GCTGGAGGACAAAAGAAATATTTGGACGTCAGAGCTGATTTATATTTTTGGAAGAGCTACGTTTCCTTTTCTG
AAGAGAAGCGAGCGCGCCCCATATCCTGAGCTCGGCGGGGAGGACGAGAGGGGAGTTTTGATGCGCCAGGAAG
TTCATCTATCGCCCAGGCGCTCAGGACCCGGCGCCCCGCCGAGTTCGCCGCCCTCGGAAATATTTATTTATTT
GGGGGAAGGGAGGGCAGCGGGGAGGAGACCAGCCAGACGGGAGAAGAAAGCCCTGCCCGGGCTGGGTTGGGAC
CTCCAGGGCGCTTCCCCGCGCGGCCGCAGCCGGCCAGCCTCTGGTCTCGGTTGGAGGGCATCGCAGGCGCGGC
CTGGCGACCTCCGGGCGCCTTTGGCTGGTGTCTTCCGTAGCCCTCGGCGCGCACCCTCCCGCGTGCAGTGCCC
GGAGTGACCTCTTCAGGCCCCGCGGGCGCCTCCTGGGTGGGCCCCGCGGCCCCTCCAACCCTGCCCAGCGTGT
GTGCGCGGCCTAGCCATCTTTCTCCCCAGCCTGGGAAGGCGGGCGGGAGGAGGGGATCCGAGGCCGGGGGCCG
CGGAGCAAAAGGCACGCGGACCCCTAAACGACCCCCGAGCGTTGCCACAGCCGGGAGGGCGGAGGGAAGGTGT
GCAGAGCTCGGGGGTCTCCCAGGACGCAGCTTGGCTCCTACCGGTTTCCAAGGCATCTGCAAGCTCTGTCCTG
CGACCTAAAGCATGGGGACGTCCCTTCCAGCAGCATCAGTGGGCGAAAAGTTAACATGCTGAGGGCCACCGGC
ACCCACACTTGCTTCCAGGAATACTTGCGGTACAGGCTTCCTGACTTATTTTCTTTAGCCGCTGGGTGCCCCC
CCTTCTTCCCCCGTTGGGAGACGCAGACCGACTCTGTTCCAACCTAAGCCCCTTCTCTCTGCCTTTTGGACAA
AGCGGGCCGCCTCTGCTCTCCACTCACTCCCCGCAACCCCGCAACTCGCCACCCCTAAACGCAGCGGGCTGTA
GGCGAAGTCGAAGAGGTGCTCCGCCTGGTACCGCGGCCTGCGCACTGGGATCGGGGCCTGCAGGCCGCTGGGC
TGGCTCCTGGGATCATCCCAAGGTTTTGGTCTCGCAACCGAGGGGACCCGCGCCCGGCAATTTGGGAAGTGCG
GAAATGGGGTGAGGCCGGTCTTCGCTTGAGGGTCTCG
CGI: 190 range = chr6: 5947471-5950124
CGATGCGGATTCGCGCTGGCGCTGAACGCTGAGCGCAGGCGGGGAGGCTCGGCACTCTCCGACCTCAGTAGCG
CCCCCAAAACCGAAGTCCAGCCGGCCAGAGAGGACACTTACGTGCACACGGTCTTGATGTTCGTCTTGTCGTC
CAGGCCCTGCGGGTAGTTGGCCATGCTGTCGCCCAGCTTGAGCAAACAGTCCGAAAAGCCCTTGAAGACCGCA
TCGCACTTGCCCGCTGCTCTCACGGCCTGCACCAGATACGCTGCGGGGAGGAGGGAACACCGGTCAGCAGCGC
CACGACCCCGCCCTGCCGCCCACTGCCCTTTCCTGCGAGACCCTGGCTCCGCGCGGCCTCATCGCATCGGGCG
GCCTCTCCCAGCGCCCAGCCTCGGGGCTCGCCAGTGTTAAAGGTGAATGAAAGACGTGACCCAGGAATGCCCG
ACCTGCAGCTAACGCTGCGTCTAGTGCAAATTGTCGGTGTGTGAGCAGGTGTGGGTGGGTGGGAGGTAGGTGA
GTCCATTCCTTTCCTCCAGCTCCCTCCCGCATCTCGCTCCGTATCTTTTTCTGTTTCCATCGCCCCCTCTTCT
CACCTCCCTCATCCCTTTTATTTCTCTTTCTCCTCGCTCCCTCCTTCGTCTCCCAACACTTCCCCAGCAAGCC
CTGTCACAGCTCTCGCAATGCGATCTTCCATTTTGAGGTGACAGAAGGGGTCTCGGCTGCAGCGTGCGGGGGC
GAGAACGGGGTGGGGAGACGACAGGGCGTGGGGTCACGCAGCTGAACCCAACGCCACATCACGAGAATAAGCC
TCAGGCTTGGCGCTCTGTCCTTGGTGGGCGCTCAGCAAACACTGCTGAATGAATGAACGAATATAGTCCCTGG
AAGCCACCAGCAGTTACCGAAATGGATTGTTTCATTATAAAACCGATTGCCTACCGTGGACTCTGTATTCCGA
GTGAGACCCTCGGATGCACCCTCTCCCGCCCCGCTGGAAAGAGGGCAGCCTGGACGTCCTGAGACCTGGCGCG
GATGATGAGTGGTCTGGAGAGGAGAAGGCCAGAGGCCGGGCGGGGTCACGGATGAGTCTGCCTGGGTCACCTC
CGCAAAGGCCAAATCCACGAACCTCGGGCCTCTTTCTCTCCTCCTCCCCTGTCCGCCACTCGGCTCCCCAGAC
ACCCTTAACAACCCACCCGCCCGCCAAAAAGCCCGCCTACACTCCGGACGGCAGCGGGGAGAGGCTGTTCTTC
TCCAGGTGCCAGCCCTGCTGCTGAAAGTGAGCTCGCCGCGGCCCGGGGCTCCTGGCCCCAGCTCAGGACTCCC
TGCAGAGAGCAGGCAGGGATAAAAGCTGAGCGGCGGGAGGAGGAGGAGGAGGAGGAAACACAGGCCGCACGAA
GGTCCAAGCCCCAAGCCCCCAAGCCCCCGGCCTCTGGACGGCCAAACCCCGAGGCGCGGGACTGGAAGGACAG
GTACCAGGCTGCGGGCGCGCGGCTGTGGCCATCTCTTTCCGCCCTGAGGCCGACGAACCCGGCTGGAAGCTGA
GTGCCTAGCGGCCCAAAGCAGCCCGGGCGCCGGGAGGGCGCCAGAGAAGCACAGCGTTAGGGCGGGGAAGAAA
GGGTGAATCTCAGAATCGAAATCCGCACTGGCGCCCACGACCCTGGGCGCCGGCCTGGTCCTCGGCAGCTTTC
TGGCGGCTGCGCTTGTGTGTGAATGTGTCCCGGGAGGACCGGACACCTCAATCCCCCGGCCCCCAACGCGGGC
GCCTGTCCGCGAGCGCCGGGCCAGACGCCGAAGAGGAAGGTGACCGAACCCGTAGCAGCTTCCGAGAGCGTAC
CCGTTTGCAAATTGCTGCAGGAAGAGCGAGGCGGGCCTTGCGCTTTTTAATCCGGAACGGGAAGCACTGGGGA
AGGGACCGAGGTTAACTTCGACCTCCGCTGGGGCAGATACGTAAACCTTCTCAAACCTCCGAGTTCACCTTAC
AGCGAACATTAAATACCCTTGCGACTACAATACTAACAAATCGAACACTGACGTAAAATCTTAAGAATAAACG
AATCTTTGTTCTGATAGAGCTCGTTCAAAATGGAAATACACTCCACACATCTTCCTCTATAACGCATGTCACA
AATACAGCTTTGCAGAGAAGAAACGAAATAAAATAAAGTCCAATCTCCCCGTCCACGTCTCTCCCCACCCCTT
GCCTACACCCCCAAAACTCAGTGGCGAAAGAAGCCCCTAAAATGCATTGACATTTTTTAAGGGGAATTGGGGC
TCGCCGGGGGCGGGAGCGCTCTTGTCACGTTATCTTCCCAGGCGCTGCTGGAGAAGACCCTGCACACCGCGCA
TGTGTGAGTGTGTGCTGTGTAAAATAAGTCGTGAACATTTCTGTCTTTTAAAACTGTGACTCCTTGGACTCTA
GCCTTCTCTGGGAGGCCGGGAGGCTGCGCGCGGGACGGATTTTGCAGGCGCACGCGTCCCAGCAGGTCGCAGC
CCGTGGGTCCCTCGCTGTCCTTCCTGAACCCCGCTTAGGCGAGACTCTAGCGGGTGACCCTGGCTCCTTCCCT
GTCCTCTCTGCCGTCCCCTTCTTGTGCGGTTTCCATCCGTTCATTCATTCGTTCGACCTCTCATTCATTCCGA
ACTTCCTCCTGCTGCGTCTTCTTTCG
CGI: 40 range = chr6: 10498025-10498551
CGTTTCGGGTGCGGGGTGCTGATGCTGCTTTTTTGTTGTTCGTTTGCGCTCGCGCTCGCTCTCGCTCTCTCTC
TGCATCCCCCTCACCCCCTTTCTCGGAGACTGAACTAAGTGAAAAGTTGTTTCAATAATCGCAGCTCTCTGCT
CCGCCAGGGCCGAGGGAGGCGGGCGGAACACGGAGGGTGTTTTGTTAAATGCTCCCGTCGTTCGCAGGGGCTG
GGACTTGATAAAAGGAGACAGTTTTCTGAAAAGATTTGATTGAAATGGCGTGTGCCAGGGCTGATGGGAGCCA
GCGAGGGACAAAGCGCCGAGAATCCATGGACACTCGAGCAATTATGCCTCCACGCTGAAGGTGGATTAGCGCG
CTGGAAAGAAGCATATGTTTGGCCCGGGGCGACACTTCCCCCCGGCTGAGCTTAGAGAATGGGAGCGCGGAGA
GCGGCTGGACCCGGAATATCAACTATCTGCGAAGCCCCCCCTTCTAGCCCAACTCCGCCAGCCTCCCCGCCCC
CGCCGGGGAAAAGTCG
CGI: 100 range = chr6: 22677564-22678684
CGTCCGAGGGTGGGTCCAACGGGCTTCGAGTGTTCGGGAGATAATGCACACTTCGCAGTGGATCTTCTCGGGG
CCCCGAGCGTTGCCCGCCCATTAGGTGGCGCCGGTCCCCTCGAACAGGTCGCTCAACAACTCCCGCCCAGCAG
CCGCCCTTACTGCGCGCGCGCAGACTTCGGCGTCTACTTCCGGTGTGGCCCAGGCGGGGTCCGCAGAACCAGC
TATGTCGGCCTACGGCATGCCCATGTACAAGAGCGGGGACCTGGTGTTTGCCAAGTTAAAGGGCTATGCCCAC
TGGCCGGCGAGGATAGAGCACATGACCCAGCCCAACCGCTACCAGGTGTTTTTCTTCGGGACCCACGAGACGG
CCTTCCTGAGTCCCAAACGCCTGTTCCCGTACAAGGAGTGCAAGGAGAAGTTCGGCAAGCCCAACAAGAGGCG
CGGCTTCAGCGCGGGGCTGTGGGAAATCGAGAACAACCCCACGGTCCAGGCCTCCGACTGCCCATTAGCCTCA
GAGAAGGGCAGCGGAGACGGGCCTTGGCCGGAGCCCGAGGCCGCAGAGGGCGACGAGGACAAGCCGACCCACG
CTGGTGGCGGCGGCGACGAATTGGGGAAGCCGGACGACGACAAGCCCACTGAGGAGGAGAAGGGGCCGCTGAA
GAGGAGCGCGGGGGACCCGCCGGAGGACGCCCCCAAACGACCCAAGGAGGCAGCCCCCGACCAAGAGGAGGAG
GCGGAGGCGGAGAGGGCGGCGGAAGCGGAGAGGGCGGCGGCGGCGGCGGCGGCGACGGCCGTCGACGAGGAGA
GTCCGTTCCTCGTGGCGGTGGAGAACGGCAGCGCCCCTAGCGAGCCGGGCCTGGTCTGCGAGCCGCCTCAGCC
AGAGGAGGAGGAGCTCCGGGAGGAAGAAGTCGCGGACGAGGAGGCCTCCCAGGAGTGGCATGCCGAGGCACCG
GGCGGCGGAGATCGCGACAGCCTGTAGTTACCAGCGTTTCCAGAAGAGCCCCTGCCCCGTTCCTGCTGCGGCC
TGGCCGTTCTTGGGGAATCTGACCACGGCGTGCAAACTGGGACTGCCTTTCCCTCTCCTCAGCCCGTCCTCCT
CCAACCCGCGCTCCTTTGCCCTGCCG
CGI: 20 range = chr6: 25834434-25834701
CGCCGCCCAAAAGCTTATTGAGTTCCTCATCATTGCGGATCGCTAGCTGCAGGTGGCGGGGAATAATGCGAGT
TTTTTTGTTATCGCGAGACGCATTGCCTGCCAGCTCAAGGATTTCTGCTGTGAGATACTCTAACACTGCCGCC
AAATACACTGGTGCGCCTGCCCCTATCCGCTCTGCATAGTTTCCCTTACGAAGCAGACGATGGATCCGGCCTA
CGGGAAACTGCAAACCCGCTCTAGAAGAGCGAGACTTAGACTTGGCGCG
CGI: 71 range = chr6: 41176454-41177326
CGGCTTTATCGTAGGAGCGTCTTCGCCTCCCCCGTTTCCAGTAGAAAAGACAGCTTTGCTCCTTTGAAAGCGC
AGACCGCCGCACCTCCAGCCCCTTCTCCCCGGGGAAGTAGGCCCCGCTAAGAATGTGGGAAGGTGGTGGGGCG
GCGACTGAAGTCGCTTCCGATTGGCGTTGTCCCAAGGAAGCCTGCGCGGATTGATCGGCGGCAGGCCTCCAAT
AGAGCCTGCTAGGCGGATTGGCTGCTACGCGGCTGGGCCCTGTTTCCGGTACCTAGGCGGGCAGCCATGGTGA
CCGGCGAGCGGCATGCGACGCCGCCTCTGTGGCCTGTGGAGGCCCGCTTGGCGGCGCTGCTTCCCGACCTACT
GGTCTTTCGGAAGCCTCGGGGATGGGAACCCGAGCTCGCCACGGCCCAGGGCGTCCTCCTAGGCGTCCATGTG
ACGGGTGAGGGCGACGGCCGGCACTTGCACTTAAGTCTCCTGGCCTGCGGGAGAGGCGGCCGTTGGGTCTAAG
CCCCTGGAGGCCTCGACGGTTACAGGCCTAGCCTCCCGCGAGCTAAGGCACAGTTTAACTTCGTGCTGCGGCT
TCCTTAGGAAACTTTGAGTATCTTCGTTTTAGCGTGGGAGGACATCTTTTGGGATGAACCGGCTCAGTCCTTG
AGCTCACCCCAAAGATGATGAAATTGAAACTCAGAGGAAAGGATTTTTACAGGACCACGCCCCGGGCTTTGAA
CCCGTTTTTCCCAACCCCGAGCATTTTCTATTAAGCGTTCTGTTTCAATTATTTTATTCGTTCAGTTAATTCG
TTCTTGGCGTCATAAGTATATGCCCGCCGTTGTTCTGGCCGTAGCTATCTAGCAGCCACTCCGCGAGTCG
CGI: 68 range = chr6: 50895246-50896050
CGTCCGAACAGAAATCGCAGCCGCCTCCTGTGTGGGCATCTTTCACGGAAATTTCTGCCCACGTTCAATGCGT
ACGGGTCTCTAGCACTGAGGCTAGCTCAACTCTTCGGGGCAGGAGAAGTTGCGCCCAGCCAGGAGGACGCCAG
CCGCCTCCGGGGCCCGGACCGCGCTCGCCAAAGCCCTTTTCCGGCTCGGGCGAGGGCTGACGCGGCCAGACGG
CTCCGCTACTCGCGGGCGAGGCGGACTAGGCGGACGAGGCGGCCGAGGCGGGCGAGGTGGGAGAGGCGGGCGA
GGTGGGAGAGGCGGCCGAGGCGGGCGAGGCGCGGGGCGCGCGGCGGGCCAGGCTGGGGACCGGGAAGCCCGCG
GAGCCTCGCTTTTAAGCGGAATGGTCTGGGACAGCCCCAGGTGGTTGCCAGGGGAAGGGAGGAAGGGAAGGTT
CTGCTGAGACGTCGAGGTTGGAAATAAAAACTTCGGAAAGGCGAAGCGGATTTAGAAAAGGAGGGAAGTCGAG
GCGGGCGAAGCGGGCCATGGAGATTGCTAAGAGGAAAAGTTGGAGAGAAAAGGAAGGAAGAGAAGCAGACTCC
CGGGTGGCGGGCGCGGGCCGCTAGGTCAGACGAAAGGTGGAGGGATGCAGAGGCTCCCCAAAGAGCCGAGAAA
GACACGCGACCCCTCCGGATCGGGACAGCTCCTGAAAGCCCGGCGCAGAGCCGCCTCGAAGATCCTAAGAGTG
GGCGACTCACAGGCGCGGCCGGCAAGCTCCTGGGGGACTCGGGCTCGGACGAGCGCCCACAGGCAGCGCCTGG
CG
CGI: 43 range = chr6: 75968300-75968853
CGGCGCCGTTTTGGAAACCCATCTCGGAGCGCCCCACTGCCTCCGCGGGAAGGTCCGACGCACCCGGCTGTCC
CTGAGGGAGGCAGGATGGAGCAAGGGCAGGACACTGGAGGTGGTGCCCAGCAACTCCGGCGCGCGCTTGCTTC
CCAGGCTGGAAACCTTGGCCCAGGCTCAACCTGTCTGAGCTGGACCAGTCCAGGCCACGCGCCTTGGAGCCCT
GCTAACCAACAGGGACAGCCGCGACCCTAGGTCGTGCGAACACCTGGGGTCCCGGATCTCCGCTTGCCTGCCA
TCATCCCCCAGGCTGCTTGGCTGCTGGCTCATCTGCCCGCACCGTCCGCCCCGCCGACTGAGCTCCCCACAAA
GCACACAGAGGCGCAGAGCCAGCGCTGTTGGAGTCTTTTATTGTGTTCTGTCACCGAGGTCGCAGCCCCGAGC
CAGGTGGTTGGTTACCAGCCAAGCGAGCGAGTGCGCCCGCTCTTCGGGGCTCCTGGGTGCCACCCGGAGGTGT
CCTGTTGGTTGCGCTGATTAGAGCCGTCGCCCCCTCTCGGGCG
CGI: 27 range = chr6: 101953488-101953856
CGCCTTTTGTGCCGGGCTGTGGCTCGCTATCGACATCTCGTCCGTTACCAAGGCTGGGTTTCCTACTGATTTC
CCTCCTCCTCTGCTTTCACAGGCTCGCGCGGCCGGACATTGTGGGTGTGCGTGCTGGATTTCTCCCGGATGCT
CTCCGACTAACATGGATGTCCCACCATTCCTTGCAGTGGAAGGTTGTTCCTTGGCGCAGTGAGTGAAGAACAT
GCAGCGATTGCTAATGGGTTTGGGAAGCGGAGACTCCTTCCTCTCTCTATGACCATGCCGTGATCGTGTCTGC
GGTCACCACTCGACGCATCCTCATTTCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCG
TGCG
CGI: 318 range = chr6: 108592365-108597232
CGCCGAGTTCGAGAAAGCGCTACGCCGCCGGTCGGGCTAGCTCCACAAGCGGCTGTACAAGTTGGCTGTCAAA
AAACGCTGATTTCTCCTCCTGTCACCTAATAAACCCCTACGCGCTTATGGCCTCGTCCCACAATCCCCCAATC
TCGTCCCAATTCGAAAAACCGAGGAGGAGGGAATAAACTGAGAGATAAAGATCCCCCCATCTTGCTCTTTCCC
CGGGACCCCAGCCTTGGTCGCGGCGCCCCACTAAGGAGGACACAGGCTCTGGTGTGTGTGGTGTGCGAGACCC
CGAGCTCGAGGCCGAGCCAAGGCTGGGCAGAAAGTTGCAATCACGTGCTGTCGGAGCCCACTGGAGCGCACAG
CCCGCTCCCCCTGGGACGCCCAGGCGGAGGACCTGCTGCGCCCTCCCAGGGCTCGGGGGACTCCAGCATTCAC
TTGCACGCACAGGCGAACTCTGATTGAAAGCCCGGGATGACACCGAGTCTGGAGAAAGAGGGACCGGGGGGTG
GGCTGGCGGAATTGCAGAGCGCCGGCCACAGCTCCCCTCCCCGCGAACGTCGAGCGGAGGGCGGGAGGTGTAA
CCTCTGACCTCTGGCCGGGTCCACGCCCTGAGGAGGGACTGGCAAGCTCTTGTTCGACAAGTTCAAGCTGCCG
AGAGAGCTTAAATAGAATTAATCTCTTAGAGATCGGGGATCATCGCTCCCTCGGCATGCGCTCTCCCAGCGCC
GCGCACAGAGCAAGGCGCGAGAGAGCTCAGGAATCGCGGGAAGGCAAGCGGAATGGGGAGGGGGTAGGGGATG
AGGGCCTCTCTTCACTATTCCTCCGCCCGGAGAGCGGGAGCCCGCAACGCCCGCCGAGGACGAGCGGCGGGAG
GGAACGCTCTGCCCTCCAGCCGCCCCGGTGCAGATAATGGAGGCGACAAGAGATTCGCTCAGCGTCGGATGGG
CCAGCTCTGCTTGGGGAAGCTGGCGGCATCCTCCCCTCGGCTGGTGCCCAAACCCACTGCGCGAAGGCCGAAG
GAACGCGGAACCTCCAGAAGACCCCATCCTCAGCCCTGACTTTCCGTAGATATGTGCAAAATGAGTAAATTAC
TCACCTCGGGCCAGATCCAAGTTTTACCCAACAGAAGGGGCACCGGACCAAGAATGAACCAACTCACATGGCC
ATGTCCGGCGCGCACAATCACACGCCAGCACACAGCCACCCAATTTCTTCCGCGAATCTATCTGGCACTCTGG
AGAGAGGGGGAAAAGCGTTTTGAGAAAGCCCCGTCACCCCTCCCCTTCCTTCTTGCCGTGAAATATACGAATT
CATTTTTATTACGAGCCGCACCGTCCTCACCATCACGCACGCACAGAGCCACACTCCCATATTCACACTTTCT
AACTCGTAAGCTCCGACAGCGCCTGCATTTTCTTTGGGAGCCGCTTGGAGGTTCATTAATATCATTAGCATTT
AACCCCCTCCCTCTTCCCATCCCCTCCCCGCACATGGCTGACGTCAGACCCCGCCAGGAGTTGGGGGAAAAGC
TAAGTGGGCCAGGGACGCCCTATTCCCCTCCCCGCGGCTGCCTGTCAGAGCGCTTCTGGAGATATTACAGGGG
ACCCAGCCCGCAGCGACAGGCACAAAGTCACGGGGTAATGAACTTCGGGGACCCTTCGCCGCTGCGTGCGCGG
CTCTCCCCGGAAACCCGGACCTGGCCGCCTCTTCCCTCGGAAGATTTCCCAGCAATCTAGTTTTCCCACTCTG
CGCTTGGGTTCCGGCAGCGCGGAGCCCGTCTGCCTCTGAGACTGCGGTAGTGTTTTCCTTCTTTCCTTGGGAG
ACCAGCGGTCGGCAGAGATTGCCCACACTCTGCATGCCTATGTAGAGGGAGAGATCGAAGACTGAGTGACAGG
AATGGGGAAAAAGAGGGATTTCGCTCCGTAGGAAGGCCATTTTCGTGTCTCCATCTCTGTCTTTCAACATCCC
TCTCTTGCTGTTCTTCCTTCTTCCTCAGTCTTCCTGTCCATCTCTCCATCTGTCTGTCCATGTGTGTGTCCAT
ATCAAGCAGCATTCCCAGCAGCTGCGGTTTTGCAAGAGCCGGGAAGAAACTTAAGGATGCTTAAATTTCCACT
GTTGGACGAATTCTGAGCGCCCAGGGAGCAGCGCAGCGCGCGACTGACACCCACCTGTCCCGCCCAGGAGCCT
TGCAGGCTGGAGGGCAGCTGGAGAGCGGCGGCGCCCGGCGGCGAGGCGGGCGCTGCCGGCCGGGACTCGGGCA
GCGCCCACCAACCGCTCCGCCCCGGGACAGCCAGCATGAGCAAGCCAGCCGGATCAACAAGTGGGTACCTCTC
GGGCCGCCGTGGGGCCTAGGCGCGCAGCCTGGGGCGAGCGAGCGGGGAGGCTGGGGGAGGTCCTGCCTGGAGC
GCTGCGAATCTGAGCCCCTGAGAGGGATTCCAGCGGGCGTGTGCGTTCGGCCCAGACCTGTAGACCGTGAGTT
GGAGCATTTCGTGGAGAGGGGAGAGCCGTTTCGTTGCCTCTGGATTGCTTGATCCCCCCTGTCTGGTGCGGTG
AGAAGGTTACGACCCGCGCAGCCCACCAGTCGGATGAGTTGTCTCCATTTAGCCGCCAGGTGCTGGATGGGGG
GGCCATGGGGGCGGGAACTGGGCCGCAGCTCCAGGCGGTAGCACAATAACACACTCGCTCAAAACTCCGAGCT
CCAGCGCGCAAAAGCAACTCTGTGCAAAGCGGATTTTGAATGGAATGCTTTGCACCCCGTTTCTAGCTATTTC
AAATAATCCTGCAAACTGGGAAGCAGAAACAATTTAAAAGTCACATTTTCCTTAATCCTAAATCCGCGTAGGT
CATAACTGGGGAATTTAAAGTATGGCGAACCACTCTAGCAAAGAGAGGACCAAATCCCTAATCCCAAGGACTT
TTCGAGCCGGAGCCCAGCAGAGGCAGGAGTGCGCGGCCTGCTCCCTCCGTGCGCTTCTCTCCTTCCTCGAACT
TCCTTAGCTGCCGGCTCTCCGAACGCCAGGCCGCAGCTGACCTCTCACCACCCCGAGACTCACGAGCGCAGGG
CTAAGTGTGTGTGCGAGGGCATTTGCTTGCACCCTGCCTGCGGAACCCAAGAATGTGCAGGCCCGAGCCAGCG
TTGAGCAGGCGCGGTCACGGTGCTCAGATCTCCCGGGGGCATTTCAGTTCCCGCCATCCAGTGGCCCACGGCT
GCGGGCTCCAGGGTCTGAGGCTGGGGACTACCGTTGCCGCCGCAGTCCCCATATCCCGAAGTTGCCTTGCTGC
TTGTGTTGTTTTCGCAGATAGCATTTTTGGCGCTCTGTGCGTTCCTTCCCTCCCCCTCCCCCTTTCACTCGCC
CTCATTGTCCTGAGTCTTTGAAAGTTGGGAGAATCGGAGATACTTCTGAGGACTGGTAATGAAGTCTCACTTA
AGTGGGATGCAATTCCCGCCCTCCTACCCCCCTCCAAGAAGGAGGTTGTGTTTTCATTTTGTTTTGCTTTGGG
TGCTGACCTTTAAAAAATTAGAGCAAAATGAACGTGAACAAAAAGAAAAGGAGAAATGTTTCGAGCTGGGGCA
GAGGGAGCAGAGAAGGAGCCCTCACCGCGGCCGGAATGCAGAGCGGACCCTGGCCCAGGACTGGGTTTCCCTT
TAGGCTCGGGCCTACCCTGGCCCTCGCTGTTGGAATCTCCAGGAGGTAAAGCGACCTCGATTTTTGTTGCCCG
CATTCCCGGGCGTGAGTGTCCTTCCCAGGAGGCTCAGGAGGCCGTTTCTGTTGCATTCTGAGCCTCCGTTGCA
AAAACTGAAGCCCGTGGGTCTCGGCAGGCCTCCTAGCTCGCTCGCCCCGGGACAGGCCCTCGCCTACACCCCT
GGAAGTAAGGAGCCCCGGGCTCTTTCGTCCTTTTCGGGGTGTGGAGCCCCTGGGGCCCTTGAAAGGTGAGGCC
TCAGAGGCGAGGGAGGGGTGAGCGGGGAGCTCTGCCCGCCTGCGGCTGCGCCCCCGCTGTGGACTAGGAGGCA
GGCCAACCCTCCGGACTTTGGGGGAAAAACCACAGCGGGCTCCTTGCGGAAACTTTGGCCGTTCTAACTTGCC
AAGAGCCTGAGTGAGGCCTTGGAAGCCTCCAGCCCCGGCTCAGGTCGGGACGCGGCTGCTGAGCTTTCTCAGG
CCCGCAGGACAGCGGCCCCCGCCGGTGGCGCCGCTGCATTTAGGCCCTTTCCAGACCGGTGGCGGCAGCCAAC
CCGAGACTTGCGTCCCTCGGGCCCGGGGCAGCTAGGAGGTCGGCGCGCAGCGGGCCGGGTCAGGACTGGGTCG
AGCAGACAGAGCTGCAGCCCCCGCCTTGCCCGGCTTCTCGCGGCTGGAGAGCAGAGCGATGTCACCCGGAGCC
CCGCCTGGGTGGTAACGAGACCCTGGCCAGTCACCCCTGCAGCCCAGACTAACTTCTTTCAACAGCCTCTGAT
GGTAATTACAGTAATCGAAGCTGCCATATATCTTTAGGCAATTATGACACACAAAAAGCCCCGAGGGGACCCC
CTGGCGAGGGAAGTTAAGAACGGTTTTCCAGCTTCAGGAAACTCCGGCTCGCCTCACGTCGGAGCTCGCTCGG
CTTGCTAAATGAGAGGAGCTTTGCAACGGGGTCAACCAGCTTGTCTCGTGACCCCAAGTCACCTTAACGTGGC
TGGGTGGCGGAGTCTGAGGCACAGGCCCGCTATGCCCCGGAATTTTCGCGTCCCTCCCTCCTGGGCCCCGCCC
CAGCCCGGTTGCCTGTTTCTAATCTGCCCCGGGAGCCGCGGCTCAGAGGTCTGCTCAGAGGCAGGACTCGCAC
TGGTGGTGGCCTAGAGGGCAACAGTCCGGAAGCTCGGGCGGGGGAATCCG
CGI: 38 range = chr6: 126122028-126122524
CGCGGTACCTGAGCTCCGTGGAAGGCCTGGACTCCTCGGATCCGCTGCGGGTGCGGCTTGTGTCTCATCTCAG
CACTTGCGCCACCCAGCGGGAGGCGGCGGCCATGACATCCTCCATGGCCCACCACCATCATCCGCTCCACCCG
CATCACTGGGCCGCCGCCTTCCACCACCTGCCCGCAGCCCTGCTCCAGCCCAACGGCCTCCATGCCTCAGAGT
CAACCCCTTGTCGCCTCTCCACAACTTCAGAAGTGCCTCCTGCCCACGGCTCTGCTCTCCTCACGGCCACGTT
TGCCCATGCGGATTCAGCCCTCCGAATGCCATCCACGGGCAGCGTCGCCCCCTGCGTGCCACCTCTCTCCACC
TCTCTCTTGTCCCTCTCTGCCACCGTCCACGCCGCAGCCGCAGCAGCCACCGCGGCTGCACACAGCTTCCCTC
TGTCCTTCGCGGGGGCATTCCCCATGCTTCCCCCAAACGCAGCAGCAGCAGTGGCCGCG
CGI: 270 range = chr6: 166499964-166503413
CGTCGCCTCCCGTTCAAGCAGCGTCCCTTCCCACAACCCCCGTGCAGAAGGCGCAGCGCGGCCCCCTCCTCGC
TGGTCCCAGACCTGGCGGGCTCCTCACACCTACCTGGCCCCCTCCGTTGAGCTTGTTGGTGAGCTTGACTTTG
CTGAAGGAGACGGGAGCCTTCATCCAGTGGGCCCCGAAGTTGGGCGAGTCGGGGTGGATGTAGACGCAGCTGG
GCGCCTGCGGCTCCGGCTTGCCCCCCGGCACCCATTCCCCGTTCACGTACTTCCAGCGGTGGTTGTCCGCCGC
CACGAAGTCCAGCAGGAAGGAGTACATGGCGTTGGGGTCCAGGCCAGACACGTTCACCTTCAGCACCGGAAAC
ATCCTCCTGGAAAACACGGGGCGGGCGCAGGAGGACCCCGACACTGACCAGGTAGGCCGGAGGCAGAAGCTGG
GCACAGAGGCCTCAGTTATTTCGGGGCACAGAGGAGCCCCCTGGGGAACGTCCGAGGGTGACTCCCAAGCTCC
CCCTTCCCCGAGCCCTGCCAGGTCCAGGTGGCCTCCTCACCATCTCCACGGCCTCGGGAGGGAGGGGAGGAGA
GGACCTGGCGAAGGGTTTCAGTGCAGGAGGCCACATCCCGCGGGGACAGGCGGGGACCAGGGCGCGCCTCGCG
GGTCCCGGGATGCCTCCGAGGTCGGGACACCGAAGTGCGCGTTCCTCCTCCCCAAGCTTCCGCGGAGAAAGCC
CCAGAAGAGGGGCTTGTAGAAATGCACTCGAGGGAGTTAACCAGAGCGGGAACAAACACAAAGCCCTCCTCCA
GGAGAAAAAGGGTTCGACCTCCGGGAACTTGCCAGGTCCCCCAGGCTGCCCAGGCGCTGGAGAGCGCGGCGCG
CGCGGGCTCCGGACGCGCACCCACCTGCCGTTCTTGGTCACGATCATCTCATTGGTGAGCTCCTTGAAGCGCA
GCCACAGCTCGCTCTCCTCCAGGCCCACGCGCAGTTCGCGCTCTGTGGGGTCGCCCTTCTCGCTGCCCGCCTG
CAGCTCATTCTCCACGGCGCTCAGCAGGTGGTCCACTCGGTACTGCAGGCTCTTTCCCGCGCTCTCGGTGCCA
GGGGAGCTCATCCTCCCGTCCGGCTCCCCTCCCCGCCGTCCCCGAAGCCCAGACTCGCTACCTGAGATCCACC
TTCCCTGCTCTTGGCCGCCGCCCTTCCGAGAAAAGGGGCCCCTTGGACCGAGACCTGCGACGGCTCCCGGGTC
CCGGGTCCCGGCACAGACCCGGGAGGAGGGCGCGGACCAAGACTTGGGGGGAGGGGACGGGGGCAGAGGGGTG
GGGAGAAGTTATTCCACTTGAACTCCCCAAGGCTCTACTAGTGTAGGTCTCTGGGGACCGAAATTCAGTGCCC
TCCCCATAAATAGAGCCGCGGCGGCAGCGCTGGGGTGCTCGGCGGATTGGGCCGCGCACGCTTTGAAGTGCCG
GGCAGCCTCCCATTGGCCGAGAGCGGCCATATCAGACCCAGCCGGGCGGGTCTGGGAGGCCGGGGGCCAACAA
TGGGCTCCCGCACGCCTGTTTCATGTAAATCCGGGGCCCCAGCCCTGCGAGCCCCGGCCCAGCCCCTACACCC
CCGCCCTTCTCCAAATGTTTGCACCTCCATCAAAGCGGCGGGGCAAGCCCCGGAGGAAGGTAAGCTGGACGCC
CCGGCCTGCCCCAGCCCGCCCCAGCCCGCCCCAGCCCGCACTTCCGCGAGGGGCTGCCCGGCAGCCTGCGATG
CTCCCTGATTCCCGCGCGGGGTCCTCCTCGCTTTCCCAGCGCGCCCGGATCCCGCAGCCGCGCCAGGCTGGAA
CGTTCGCGCGGCCTCACCTGTCCCCGCTCCAGGCGCGCCTCCCTCCCCTCCCAGGGACGAGCGCATTTGGCCG
GGCTTTGGGATGCGCCGCGCTCGTCTCGCCGCAGTAGTAGTGCTGTTCTCGCGCCTCCGATGCCTCAACTCTC
CAGTCTGGCAGTTTCCGGTGCACCTGTCCCCACACGTCCCTCGCCCACGGAGCCCCAGGCGGCGTTACGCACA
CCCAGGATCGTGGATCAGCCTGCCCCGGCGTCGGGTGTCCCCGCGGCTCTCACCATCTGGAAAAGGAAGGTCC
GCGCGCAGAGAGGGAAATGGACGGAAATAAGCAAAAGCAAAACAACCCCTTCTGAGAAGTGTCCTCCTCGCTC
TCTTATAAAAACAGGACTTGTTGCCGAGGTCAGCGCGCGCATCGAGTGTGCCAGGCGTGTGCGTGGTTTCTGC
TGTGTCATTGCTTTCACGGAAGGTGGGAGAAGGTCGGGGCTGGCGGGGTGGTCCGGACTAGTGGGACTCGGGG
CGCTTTCCCCGCCCGGCCCAGCGCCAAGCGGTGTCGGCAGCGGTTGTTTTATTACCTTTCGGTGAGAACTTAC
GCGAGGAGAGCGAAGGAGAGGTGACAATGAGCAGGAAATAGTTCAGTGGGGTCTCTTTAAACAGTAACATTCC
TCCTAAAACGGGAGCCCAGGAAGGGGGAAGGAGGCAGAAGCTCCCCCTTCCAAGGCCTGGCTTTGCGCTTCTG
CACACCTCGCCCATTCGCTGGACGAGGGCCTGCCTCGGGTAGCAGCCTCTGTTTCCCGGTCTCCTGAGCGGGC
ACCCCAGCCCCAACCCCTCTAGAGAAAGCCTGCGCATCGGGTGGGGCAGCGAGTTCAGAGGAGTCTTGCGCCC
TAGCAAGGGGGCTTTCCCGCGGACATGGTATCTGCGCCCCGCGCTAAGTCTCCCCTGCCCCCTGCCCCCTGCC
CCTCGCCCCTCGCCCAGCCGGGCTCGCTCCGGGGTCGGGAATTGCTGGGGAAGCCGAAGGAGGGATCCCCGCC
CGGGACTCGAGGGATCGACCCGCCTCGCGGTATGCGGAGGGCTGCCAGGAGCCAGTCCCGGGGAAGGGTGCCT
GCCGCCCGTGGGGGACAGGGCTCCTTCTCTCCCTTCTCCAACTTACACCGACGAGTCAGGAAGCCGGAGCGTC
TAGTCCCTGTCCGCATTTCTCAGTGTCTTTTGATGTCTGGGATGCATGGATATTCCCAGGGGGCTGACCCGAG
GTGGGGAAGTTTCCTTCTAGAAAGAGGCACCAAAAGGACCTCATTTGCTCCTGACGCCGGACCCTCCTGACAC
GCCTTCACTGGCTCATCGGGTCCTGGGCTTTGGGGGAGAGCGTGGTGCGTGTTACTCTCCTTACTCCGGGTAT
TAAAATGTCTAAGAGGTCATCGCTTTGGCCCAAGGCCTCCCGAGGATAAGATAAAAGGGAAAAGTGGAGGGGA
GGTGAAGGAGGAACGAGGGTGGGTCCCAGGCAATTGAGGGCCTCGGAACCCTAGGCACGGGAGCGAAACCTCT
CCTGCGGCTTCAGGGCAAAGGAGTCCCGAAGGCTGGATCCCTCCCCTGCGCTCGGACGGCGTCGCGGCCGCTT
TTCCCACAGTCGGGAAGCG
CGI: 25 range = chr6: 169801163-169801511
CGCGGCCGGGTTGATCTCCAACACGGCAATCTTCCCGCCAAAGAGGGAGGCCAGCAAGCACAGCACCTGCAGG
GACGCGGTTTCAACATCGTTAGCGACACCACCCAGTAAAAGCAGACGAAACGTGCATCCGCACACGTATCCTA
ACAGCTGCTTCATTCTCATAGCAGCGACATCGCCCTGTCACTCCTAAAACGTTTTTACACACAAAATCCCGTT
TACTCAGCCAGTCGTTACAGGATCACTCTGAAGAAAGAAGAAATCAGAGGCACGTCTCATAGACAGGGAGGGC
CGCGTCTCAGGACTGACCTTTTGATCCGCAGTGCGGTTCCTCAGGGCACACGATCCG
CGI: 40 range = chr7: 1029023-1029492
CGCATACGAGTCCAGGGGCTGCTACAAAGCGCGGCGACGTCTCCGCGGCGAGCTGGCCACTCCATGGTCCCGG
CGCAGACACTGGGGCAGGCGCCGGCTCTGTCGTCGAGGCGCTCACAGGCAGGCACACGTGAGCTCCTGGAGGA
CAGGGAGAGCGGCCGCCCCGCCCCTGCGGAGCACAGGACGCTTCCTGCCACCCCTGCAGAGCATGGGACGCTT
CCTGCCATGGTGCCGTGGCAATGGGTGGCACCTGCCTGTGGCCCCTTCTCAGAAGGACGTTTTAAACGCGTGA
GGTCTGATGCACAGCCACAGGGAGACACAGACGAGCAGATGTGGGCATCCGAGTATTTACAAGGTCTGGTGGC
TCCTGCAGCCGCGACACGGGCTGAGCGCAAGTGATGTGTGAGGTGTCCCCAACAGATGGCACGGGGAGCGCCC
ACACCCGCCACCGCGGGGTCTGCGGAAGCTCG
CGI: 26 range = chr7: 19113449-19113833
CGCTTCTAAACCCAATACGCTTTTCTGGAGTCCTCGGAACAGCTGGCCGGGGCTTTTAGCACACGGGACGGGA
CCTTCGCCTTTGCCTGTTTTTTTTTCGACCAGGAGAAGCAGGTGCGAGAGTCTGGGGCTTAGGAGGTGGAAGG
CGGGGAAAGAGAATCCACTAGGTCCTCGTGTAGAGAACAACAGTCGCTCCTTAGATATTACTCCAGGACGGAA
ACCTGATTGCAAACCGCTGTTCCTTCGAAACTTGCAAAACCCGGAACAGAAAACTCCCGCCCAGCCAATTTTA
GCTCTCGCTGAACTCTCCCGCCTGCGTTACGTTTGCACAGCAACTCTTTGTAAATGTCCGAGTCCTCTCGGAG
GAAAGATCGTTAGGGCGACG
CGI: 207 range = chr7: 27149139-27152087
CGAGAGCCGCGTCCCCGCGGTCGCGTGGATTTAGAAAAAGGCTGGCTTTACCATGACTTATGTGCAGCTTGCG
CATCCAGGGGTAGATCTGGGGTTGGGCGGGCGGCGCCGGGCTCGGCTCGCTCTGCGCACTCGCCTGCTCGCTG
CTGGCAGGGGCGTCCTCCTCGGCTCCGGACGCCGTGCCAACCCCCTCTCTGCTGCTGATGTGGGTGCTGCCGG
CGTCGGCCGAGGCGCCGCTGGAGTTGCTTAGGGAGTTTTTCCCGCCGTGGTGGCTGTCGCTGCCGGGCGAGGG
GGCCACGGCGGAGCAGGGCAGCGGATCGGGCTGAGGAGAGTGCGTGGACGTGGCCGGCTGGCTGTACCTGGGC
TCGGCGGGCGCCGCGCTGGCGCTGGCAGCGTAGCTGCGGGCGCGCTCTCCGGAGCCAAAGTGGCCGGAGCCCG
AGCGGCCGACGCTGAGATCCATGCCATTGTAGCCGTAGCCGTACCTGCCGGAGTGCATGCTCGCCGAGTCCCT
GAATTGCTCGCTCACGGAACTATGATCTCCATAATTATGCAACTGGTAGTCCGGGCCATTTGGATAGCGACCG
CAAAATGAGTTTACAAAATAAGAGCTCATTTGTTTTTTGATATGTGTGCTTGATTTGTGGCTCGCGGTCGTTT
GTGCGTCTATAGCACCCTTGCACAATTTATGATGAATTATGGAAATGACTGGGACATGTACTTGGTTCCCTCC
TACGTAGGCACCCAAATATGGGGTACGACTTCGAATCACGTGCTTTTGTTGTCCAGTCGTAAATCCTGCCTGA
TGACCTCTAGAGGTAAACTCGTGCACTAATAGGGGAGTTGGGTGGAGGCGAGGGGGGTGGCGCGCGCGCCCCG
GGCGCGTGCCCGCCGCCAGTTGCCGCCGTTCAGCCGGACTCGAGCGCCACCCGCTGGAGGCAGGGCTCATCGC
CCAGCTTCCGACCGGGGGCTGCAAGGGCCGGGGTCGAATTGAGGTTACAGCCCATTATGGCAAAATTATTGCA
TTTCCCTCGCAGTTCCATTAGGATGTACCAATTGTTAGGCCGTCAGCTGCCGATCGCGCGCCCGGCGAGGATG
CAGAGGATTGGGGGGAGGTGGTGACTTGCATTTTATTTACAACAACTTTATTTCCCCCGTTTTGCAGCCCCTC
TTATTTTTGTGTCGAGGTTGGGGTCGGTACTGACCGTCCTGCCAGCAGCTCTGAATTTTGAAAATACAGATAT
CACCTTCGGGGAAGGGGGAAAGCCATTTAGCCAATTGGAGAAATAAATCCTGCCCGCAGCAGCAGCAGCTACA
ATTACGGCTCTGTTTTTGCGAGCGCATGAGGGACAGTGTCCCTGCCGCTCTTAAATGACAGGCGTCTATTAAA
GATAGCTTTTGTGTAGTGTTTCTCCAAGGCGAGGTCAAATTCCATACACTTTTATAACCGTAGTCGATTTTTC
TTTCGTGTGAATATGGTTTTCGTGTCATTAGTTTGCGATTTGATTTGCTTACGTATCCAGCCTGGAAAATCTT
CATCACAGGGTCCGGTTCCTCGAGCCAGCCGGGCCCCAAGTCGGAGGGTTCTCCTTGAACCCAGCGAGTGGGC
CCAGGCTCCCTGCAGCCACAGAGGCTGCCTGGGGTCTGGGGATCCGTGGGGCGGGTTACTGGGGTCTTGCTTA
GACCTCCAGGAGTAAAATGAGGGCGATAATGGAAGCATTCCTTGGCAGTGCCTAGTATCTCTGTAGTTATTTT
CCACGGCTCCGAAAGACTCAAGTAAATCACAAATATAGCTGAGAGGCAAGTGGAGTCTCCCCGCTGGAGGCCC
GGCGTTGCAGGCGCCCCTGGCACGTCTGGAAGCCAGGACTCTGGCGGCTCCCATGGCCCTGGGCCCCTCGTTG
GGTCCTGAACGCTGCTGTGGCGGCGACGCGGGCGCTATCGGAGGCTGGGAGCGGGAATCCGGAGCCGGGAGCC
TACCCCGGGCTGTAATGTTCCACCCGCGCCCAGGTTAACTCGCCTCGGCTGAGGCTGCTTCTCTTCCACTGAC
GGTTGCACACGCGGGACCGAGAGACTGGGCTCTGTTGGGGCCCCCTTTGTTCCTCGAGCTTCCTTCCTGTTCT
GGGAGGCGGCTTGGGAGGCCGCGACAAGGCCGGGCTCCAGCTCTTAGACCCCCTCTTTCCACTGGCCAGAGAT
GATTTGATGATGCCCTTCGGGACTTACTGGCGAGGGACTTAGGCAGAGACGCCCAGACACGAAACGGGGCTCG
GCCCAGGGCTCTTTCCTCCCCAGCAGCCCCGCGTCCCGAGGTCGGGGAGCTCAGAGACACTAGCACAGGAGCC
CCAGACGCATTCAGGGCGCACCCCAGAACTCCGGAGCCGGTTTGGGCATCCTTGTGGAGCGGGACTGGGTGTG
TGCAGTGCGCCCCGCTCCACCGCTGGTATTGGCTGTGTGTGAGGTTTTGTTTTGTTTTGTTTTGTTTTGTTTT
GTTTTGTTTTGTTTTGTTTTGTAAGAAATAAATGCACAGACGCTTGCAAAGCTCCGGGCTCCCCTGAAGCTGC
GGAAGCCCCCAGATGGGAGCAGGCGGGGAGAAAAGTTGGGGAACAGGCGAGGGCAAGGGGGCAAAGCCGAAGG
AGGTTGCAGCGCTGGCCTGGTCCCTGCCCAGGCATCTACTCGCCCGCCTTTGCCTCTGAGTCCTCCCCGCTGG
GCTGCGTGGAATTGATGAGCTTGTTTTCCTTTTTCCACTTCATGCGGCGGTTCTGGAACCAGATCTTGATCTG
GCGCTCGGTGAGGCAGAGCGCGTTGGCGATCTCGATGCGGCGGCGCCGTGTCAGGTAGCGGTTGAAGTGGAAC
TCCTTCTCCAGCTCCAGTGTCTGGTAGCGCGTGTAGGTCTGGCGGCCTCGGCGCCCATGGCTCCCATACACAG
CACCTACGAGCAGAAACGGCCGGGCGCCG
CGI: 201 range = chr7: 27170441-27172987
CGGAGCTGGGCAAGCCGTCAGGGCGCCCTAAGGCCGCTGATCACGTCTGTGGCTTATTTGAATAATCTGTCAT
GGGGACCCTTGTGGCCCGGGTCGCCCGCAGCCTCATCTTGGCAGGATTTACGCCGCCACTGGCCGAAGGCAAG
AAGTGGAAGGAATCGGCCGTCTCCCCCAGCGTCCCAGCTCCGGCTGCCCTGGCTGCCGCCGCTCACGGACAAT
CTAGTTGTACAAAAGGCTCTCTGGGCTGCACTGCTTTCGAAGAACGGCCCAAAGTATCTCGGTCCTGGGCCTG
GGCAGCCAAGGAGAGGGGCGGCCAGTCTTGGCTCGTCCCGAAGTGCCCGCCCCGCCCCCTCTCGCTGCAGCAG
CCGCCTCCTCTCCCGTAGCCCTGCGGGCCGCTCTTCACTGCTCTCCAGACTTGGGGCCCTATCTGAGGCGTCC
CAAACACCAACTTCTGGCTCCTGGCCCCAACTCGAGAGGCTTCCAGCGAGGACGAAGGCAGGCTCGAGAGAAA
CCTGGCGGGCCAGCAGATCCGGGAGGCCGGCGTGGAGGCGGCGGCGGATTTGAAGGGAGGAGACACTTACTGG
GATCGATGGGGGGCTTGTCTCCGCCGCTCTCATTCTCAGCATTGTTTTCAGAGAAGGCGCCTTCGCTGGGTTG
TTTTTCTCTATCAACTGGAGGAGAACCACAAGCATAGTCAGTCAGGGACAAAGTGTGAGTGTCAAGCGTGGGA
CAGTCACCCCTTCTGGCCGACAGCGGTTCAGGTTTAATGCCATAAGGCCGGCTGGAGGGCAAGCCCGCGAAGG
AGAGCGCACCGGGCGTGGGCTCCAGCCAGGAGCGCATGTACCTGCCGTCCGGCGCCGCCGCCGCCACGGGCGC
CTGGGGGTGCACGTAGGGGTGGTGGTGATGGTGGTGGTACACCGCAGCGGGTACAGCGTTGGCGCCCGCCGCG
TGCACTGGGTTCCACGAGGCGCCAAACACCGTCGCCTTGGACTGGAAGCTGCACGGGCTGAAGTCGGGGTGCT
CGGCCAGCGTCGCCGCCTGCCGGGGAGGCTGGCCCAGGGTCCCCGGCGCATAGCGGCCAACGCTCAGCTCATC
CGCGGCGTCGGCGCCCAGCAGGAACGAGTCCACGTAGTAGTTGCCCAGGGCCCCAGTGGTGGCCATCACCGTG
CCCAGCGCCTGGCCCGCCCGGCCCGACCCACGGAAATTATGAAACTGCAGATTTCATGTAACAACTTGGTGGC
ACCGGGGGGGAAGTACAGTCACCTAATAAGTTGCCGGCGCCCGCGCCCCCATTGGCCGTGCGCGTCACGTGCC
CGTCCAGCAGAACAATAACGCGTAAATCACTCCGCACGCTATTAATGGTCCGATGTTTTGCAGTCATAATTTT
TATAGCAAAAGCCATATGTTTTTATGTAAAGGGATCGTGCCGCTCTACGATGGGGTTTGTTTTAATTGTGGCC
AACGACGATTAAAAGATCAAATCTAGCCTTGTCTCTGTACTCTCCCGTCTCCCCCCCCATACACACACTTCTT
AAGCGGACTATTTTATATCACAATTAATCACGCCATCAAGAAGGCGCGGGTCCCGCGTGCGAGTGCGGCCAGC
GGAGCCCCTCACATAAAATTAGACAATAATTGAAGCCATAAAAAAGCAGCCAAATCGCATTGTCGCTCTACTG
TATTTAAATCTATATTTATGATATTTCATAAGGAGTTATTGTTTCAGAAGCCACACAGGCTGGCGGGAAGTCG
GAAACGACCAACAGATTCGTTTGCCTCGCCGTGGCTCCCAGCTGTAAAAATTTACGAGGACTTGGAAAGGTTA
GACTGTTGTGTTTGGTTGGCGAGCTCCCTGTAAATAATCCCTGCGGTCCCCGGGAGAGGCGAGTTTACCCGCG
GCCGCCCTCGAAAAGTCAAATTCAACGCAGGATCCGTCCCAAACGGAGCCGCCGCCGGCCCTACCAGGGCACT
CCAGGCAGGGACCGGCCGCTCAGGGAGTACCGCGGGTGTAGGTCCCCACAGCTACCCGCCTGGAGCGAGGGGC
GCCCGGGCAACCCTTAAATTCGCCTTTGCTACGAGGACCCCACGGAGGAGCTGGCCAGGAGGGAGCGGCCAGC
CGCCACCAGGGCGAAGGTTTTGAGGGCCTGGTTGGTTGTGCGGCGCGCTCGGTCCCCGGCCCTCGACCCCACG
CACACGCGCGCCCAGCCCGCCTTTCTCATCAGCTGGCAATCAGGATTCCCAGGCGCAGGCGGCTGGCGACCCA
GCCCTGTGCTCCAGCCTCAGAGGCTCTAACCATGAGCGCTGCAAGCCTGGTTGCGCTCCGTGAATCCCAGCTG
GGGAAAAAACTACAAGTGGCATGAATGGAAGGCAAGTTCGGTTTGGGAAAAGGCAGCCTCGCCTAAGAGACCC
CGCAGCTCCGGAACCTGGGAGGCCCGCACCGATGTGGCCTGTCCCGGGGCCGCGTGAGCCTTTCAGGGCTCCT
TCCTCCCTTTCCAGCTGCTACTCCGGGCCTCGCCTTGGTTACCTACGGGGCCCGGAGACTCGGCG
CGI: 114 range = chr7: 27198331-27199622
CGGCGGCAGCGATCGGCCCTGACCATAGAGGCGGCCGTGGCGCGGAGGACTTGACCTTTACGGCACGAGAGGA
GGGCGCTGGCTGAGCCGCAGGGAGGGGGACGCTGCTCTCTCCAGCCTCCTCCACCCAATAGCAGTCCGCTCGA
CCCACGCCAGCTGCGCGCTCACCCCCTTTCCCCCTCCATTTTGTGCAGTGTCCGCAGACCCGCGGCCGGAAAC
AAAGCCCCCAGCCCTGCTCTCACCACCCTTCTTGCAAGCTGCTGTCGCCAACCCCCCAGACCAGAGGCTCAGA
GCTAACGCTAAGCCCCTTAAGGCCCTCTCCAGGGCCCTCTTCTCTCGCCAGCCGCCCTCAGCCAGCTCCTGAC
CCCAGCCGCCCTCAGCCAGCTCCTGGGTACCACTCTGGGTGCCAACCGGGACCTGCCGGTGCCACGGTCCCGT
GCGCCGGGTCCCGGCCTCGGGCTGCGGGCGGCTTCGGGGCCTACAGCCCAGCGGCGCGGAGCGTGGCAGAGGC
GCGGGGCGCAGCGCAGCCCGAGGCTGCCTCCCGCCCGGGCGGACGGCGCGGCCGCTGGGGTGCACAGCGTAGC
CCCGCGTGCCCGGCTCGCTCTCCGTTCCCTCGGATAGCTCCCACCGCTCGGCTCCGGGCTCAGAAAGCGGAAG
TATTTGGTAGAGAAAAACACGGTTTCTTTTCAGCTCGTCTCAAAATCCCTTTTAGAGAAAATGCTCCTGTCAA
GTTTTATTTCCCGTTGCAAACCACCTTCCACGCTGCCAAGAATTAAGACCGGGAGAGATTAAATACCCGATTA
TTCTCCTGGGGAGGGCGGGGCGGGGCCGGGAAGTGGGCACCCACACCAAACATTCCTTGAAGTAGGCTTGTCC
TGATCCAGCCGCGCCCGGGGAGCCCCACGAAGGCCCGCGCGGCCTGCGGTGACGTCAGCCTGCAGTTGCGGGG
CCACTCACCCGCACAGACACGGCCCTTGCTGTTCCGCGCCGGGACCTCCGCCAGCCGTCCTGCCGCAGCCCCG
ACTGGCCCGCGTGCCGTCAGAGGGAGGCCCGCTTTACACCGGCCTGAGCCTCCATTTTGAGTAGGGGGTTCTT
GTAGAAGCGTGGAGGGTTTGGGGCCGCGCCTCTGTCCCCGAGGGGCGCGACATCAGGTAGCTCTCCGAGTTCA
CACCCCAGTACCTGGGGGAGGACCTATGTCGCCGCATAACCGCCCGCAGAGGTTTGGAAATCTCTGAGACCCG
TTGTAATTATTTCTGCCCAGTGGATCCGGCTCTTCAGCGTCACGAGAGCCG
CGI: 111 range = chr7: 35263447-35264743
CGGTTTCCGGCTTTTGGACAATGGTCCCTCGCTTAACGAATGCTAACGAATGCTCCCTTAGCTGGGAGCTGCA
GGGACCGGTCCCGGCAGGTCTAACCAACCGTCCGCAGGCGCCGTGGTCGAGAGCAGAGCCGAGACGGCGGGGC
AGGGTGCCAAGCGGAGGGCACAGCCTGGCAGCCACCGTTGGCGGCAGGAGAGAATGGGAGAAGGGAGACCCGC
TTCTCAGCACAAGGGCATCTGTCTACTCCCGAACATGGCCGGAGATTCCTGTCCACAGCCTCCCTCCAGCTCT
TTCTGGTAGACACTTTAAAAGCGACATTAACGGGCTTCGGTGCCTTTGGATTCCTAAATTAGGTTTACGGAAA
AGGAAAGACTTCCCAAGAACAGTGAGAAGAGGAACTGCAGCCCCTCCAAGGCCGCTGCGGCGCGTTCCCGGGG
CGCGCCGAGAGCAGCGCGCGGCTCCGTGCCCCGTGGGGAGCGCGCGGCGCGGCCTTGGATTTCACCGCGAGTC
GGGAGGGCGGGTCTGAGCCTTGCCTCCCAGGATCCTTCCGACGAACACCCCGCGGGTTTTAGTTTATCGAGCC
AAAGTGGTCCCGGAGAAGCGCTCCCTCGCAGCCAAGCTGCAAGAAGTGGCCGGGAACCTACAGGCCTCGGGCC
GACCCAGGAAGCCTCCGCACCAGAAAGCTCGAGGAGCCCTTACCCAAGTCTTGCTCGAAGGGCAAAGCAAAGA
GCCAGCACCCCTGAGTGTCACTGAAGTTCCTGGATGGGGTGTGAGTGCGCGCGTTCCGTCCGAGACCTCAGTC
TCGCCCAGCTATAGAGCCGATAAAGGGATGTCTTGTGGGCGTAAGGCGCTTCGCGCCCATCTCCAAGGCCGAT
GTGGTCAGGAGGTGAGGGGAAATGTCCTTCTGGCAGAAGCCCGCGGTGCTGCGACGTTGACCCGCCTGGCCTC
AGGCTCAGGGCGGCGGGCAGCCCAGGGCACATGTAGTTTCAGCAGCCGCGCTACGTGGGCGGGGGACCCCAGG
CCACCCCACGTGTCCGCCCTGGGCCTCCTCCGGGTCCCAAGGCGCGGCGCCTCCAGGCCTTGTAGCGTCTTCC
CCGGGTCCCCGCGCGCCAGGCCCCGCAGCCTGCTCACAGGACAGCCCTCGGGGCTGCGACCCTCTCGCTCCTC
CCCGCGGCCACTCGCTCCCCGTTCATCCCCCACGAGCTCACTACCGCAGGGACCGGCCCTCAGAGCCCCGGGC
CTCCTCCCGGCAGTGGAAGAATCAGCGTGCTAACATTGTGTGCAAAACTCGCAGCG
CGI: 30 range = chr7: 96469320-96469736
CGAGGGCCTTGCCCGCCCTCCTCCTCCCACCCGCAAGGGTTGGCCCGCGTTCCCCTGCGGGCGAGACAAAGAA
GCAGGAGCCAGGACCCGGCTGGCGCCTAACCCGGCGCCGGGGCCTTGAGCCCCTGAGGTGTGCGCCTTCCTGC
AAGGCCCCAAAGAACCCGAGTTTTTGCCCCTTGCTGAAGGGTTGGAAGTGCGGGCTGGACTAGTGCAAACAAG
AGTGACTCCAACCGCCTTACTTCAGCTCATTACCGTCACCCATGAAAACGGAATGAAGGACTGGGAAGCCAAT
CTGCCGCGTTCAATTGGAGAGAAATGACTGTCGGAAGAGGCCCTGCGGTAAATAGCCTCTGAGCCGCGAACTC
TATGCGCCGTGGCCGGTGGCAGAGGCCACACCTGGCAGCCACTCGTGGCGCG
CGI: 32 range = chr7: 119702299-119702721
CGGAAATCATCGGCGACTGCTGTTATGAGGAGTACAAGGATCGCAGGCGAGAGAACGCCGAGCGCCTGCAGGA
CGACGCGGATACCGACACCGCTGGGGAGAGCGCCTTGCCCACCATGACTGCAAGGCAGAGGGTCTGGAGGGCC
TTCGAGAACCCCCACACCAGCACGATGGCCCTGGTGTTCTACTATGTCACGGGGTTTTTCATTGCCGTCTCTG
TCATCGCGAATGTGGTGGAAACAGTGCCGTGCGGATCAAGCCCAGGTCACATTAAAGAACTGCCCTGTGGAGA
GCGGTATGCTGTGGCCTTCTTCTGCTTGGACACGGCCTGCGTCATGATCTTCACAGTTGAGTATTTGCTTCGC
CTGGCTGCAGCGCCTAGTCGTTACCGTTTTGTGCGTAGTGTCATGAGTATCATCGACG
CGI: 42 range = chr7: 158509937-158510390
CGTCCTCCGACGCGAGATGGCTGTGTGCCACCGACTGTCCAAATGCCCTGCCAATGCCATCGTGAAGCATCCG
TGTGAAGGAAAAAGTCCACCTTACCGTGCGCTGTGGCATCGATCAGGCGTGTGGACAGTCGCAGGCACGCAGC
GGTCTCCCAACATCAGGGCACACCGCGATCAGGTGTGTGGACAGTCGCAGGCACGCAGCGGTCCTGCAGCAGC
AGGGCGCACCGCGATCAGGTGTGTGGACAGTTGCAGGCACGCAGCGGTCTCCCAGCATCAGGGCACACCGCGA
TCAGGTGTGTGGACAGTCGCAGGCACGAAGCGGTCCTGCAGCAGCAGGGCGCACCGCGATCAGGTGTGTGGAC
AGTTGCAGGCACGCAGCGGTCTCCCAGCGTCAGGGCGCACCGCGATCAGGTGTGTGGACAGTCGGTGGGCACG
CAGCGGTCTCCCAGCG
CGI: 20 range = chr8: 10624024-10624296
CGCAGGAGGGCTCGGCCTGGGACCCCCTCTGCGGGCCTGCGGCTTTAGCCAGCAGAAAGAGGGGCGTCAGTCC
TATCCCCAAAGTTCCGCCTCGGGAAAGAGCCCTGAGCTCTGAACTCCGACGAAAAAAGGAAGGGCTCTGTTCC
GGACCGGGTGGGGTTTGGGAAGGGTAGAGCCGGCCTCGGGTGCCCTTCTTACAGGGCCTGTCTCCCGCTGCGT
GCACCAAGTGCTTTGAAAGTTTTTCGCGGATTAAAACGAATAAAAACCTCGTCG
CGI: 221 range = chr8: 11597006-11600365
CGAGGGTGAAGGATCGCCGCAAGGCACCGCACCTCCCGCTGCAGCCCATCCCGCACTACTAGGAGAAGCCGGC
GTAGGAGCGCCGCCTGTGTCCTTGGCTGTGGGGAGGACGTCAGATGGCACCCCGCCAGACACTAAGCCCCAAG
CCCCTGGCTTGTTGCTAAGAAAATTCACTGCCCGGTCCAGACTCAGCCCTTTTCGCCCTTTAAGGGTCGCGCG
TGGGAGGCAGCTCTGAGACCCCGGGTAGCGCTGGAGCCACAGATTTCCTCCGAGAAAAGAAAGGCCGGGATAG
CTTCCCGCTCGCCCAAGCCCAGATTTTCCACTCTCCAGGAAGGCCTTGCAGGTCCCTGCCGCAGGCCTTGGCT
TCGCGCCTCTCTCGCTCGCCCCCCACGAAGATGATTGCCGGTTTCAAACCGGGAGCAGGGAGTCTGCTTCCTT
CTCCGCTGAGTCCGAAGGATCGCAGATTGGAGCGTGCTCCGGAGACCGCTTTTCCGCAGCGCCGGCCTCCGAG
ATCCCCAGCACCCCTTCAGCCTTAAGTTCCCACGTTTCGGGTCCGTGGCGCCAATTCTGCTAAGTAGCAGGCT
AGGAATTGGGGGAAGTCGGAGAAGAAACCCTAAGTGTGTCGCCCCCAGCTTCCGGGATGCAGGCCCGCCGGGG
TCTAGAGGGGCGGCTGCCGTGCGTCCAGCCTGTGCGCAGGCCTTTCGCCGCTCGGCGCCCCAGGCAGCCTCAG
TTTCCTTTCCTCTGTTTGCGCCCCAGTGAACCTCCGCACCTCTCATTCAGGGAAGAGAATTCCCCGCGCAGCC
GCGCTCGTTTCTTCCTCTGGGATTTTCCTGAGAATCCCCAGGAGTTGGCCACGATCCCATGGGGGGTTTCCTT
CTACCCAGCCCCGCGTCCTGGCCTCGTCCTTAACCCCCGGGTTGCCTTCACTCAGGCTGGGAATCCACGATTG
ATTTCCTACTACGGAAGCGGGTGGCGTTCCCAGCCTGCTTTCGGAGCAGCACGGGTTTCGTGCAGGGTGTTAT
CCCGACCCCTTCCCCCATCCCTCTAATCTGGCTTGAGAAGCCCGTGCTGGAGAGAAAAACGCGGCCTTAAAAA
AAAAAAAAAGTTTAACCGAAAGCGTGAGAGCCACCCGCCGGCTGTTATCTGGGGCTGAAGGCTGCGGTAATCG
ATGGGTTATTTTTACGCGGTAATAGGGCCCTGTGATTGCTCTATTAACCTTTAGACCTGTCTGAGGGACTCTC
CGGCTCGCAGCCCCGCTGCGCTGGGGCCTCCAGGCTCTGACGCCGACTCCCAACTCAGGCCTGACACATTCCC
CTCCCCCATACCCTGGAAGAGCCCCCTCCATGAAGAAGCTCCCCTGGACCGCCTGGCTCCCCAGCCCTTGCCA
CGTCCCTTGGATTGGTGCAGAGCCGCCGCAGGCTGCAGAAAAAAGGGGGAAAGATTAGAAGAGAGGAGGCCAC
AGGAGATGGGAAGTGTCGCCAGGAAGGGATGCAGATTGCATAAATACATAAAATTGAGGCTGAGGCCTGGGCT
CCCGACCATCTCCCTGGGATTTTGGGAAGGCAAAAGGGAGGCTTCGGTCTCTACGCTCTGATTTTAGGAGGCA
GTCTGGGTGTCTCCTGAACCTCCAAGGAATCCGGGGCTGGGAGGATCCCCACTACCCCTGCCCAGGAACTAGC
ATCCAGCCGGGCACCCCGGGTGACCCAGTGCCCCACACAAGATCGAGAGTTGAGCCCAAGAGGTCACCTTCTT
CTCTACTGGCCCCGCCCCTCGCCCGCCGCTGCGGGATGAGGACCACAGGAAGGGGGGGCGGGGAGGGAGAAAG
GGAACTCATTAATAAAGCTGACCCTGGGCACCACAGCGAACCCAATCGACCTCCGGCTGGGTTGCGGGTGATT
CCCCGCTCCCTGGCGGTAGCACTTGGGCATTTTCCGCGGAGACCCCAGAGCCTGGACTTTGCCTGCTGGGGGA
GCTTTCCGCACAGTCCCGCAGCCTGCGCCCAGCGGAGGTGTAGCCGGGGCCGCGCACCCCCGCCCCGCCCTTG
CACGTGACTCCCACAGGCCAGTCAGCGCCCTAGGGCCGAGTTGCTGGGCCGGGGACCCGAGCCGCGAGCTGGG
GACTTGGAGGCGGCCGGCGCAGGGGCCGCGAGAGGCTTCGTCGCCGCTGCAGCTCCGGGGGCTCCCAGGGGAG
CGTGCGCGGAACCTCCAGGCCCAGCAGGTAGGGCTTTTTTCTTCCCTTTCTTTGCTCCTTCCCGCGGTCCCCC
AAACTCGGAGCTTCTCCGCCTTTGCTTGTCTGGAGGTAGAGAGGTAGCTAGTGGGAGGAAAAGAGACGTGCGC
TACTCACTTCACCGAAATTGCCCAACCCCTGCTCTGCTTTTGACTTTGCCTTAGCAACTTCTTTAAGTCAAAG
TAAGACTTGGGGGCAAAACAGAGAAATATTGGAAGCGCCTTTGGATTCTTTCCGTGTGAACTTGAACGCTTTC
AATCCCTGTCCCCGTGTGCACATTCTCCAACCCTTGTTTGCATATCGCAGGCCGGGGCCTGGGTGGTGATGGT
GGCCGCGTGAAGTTACCGGGACTGACGGGCCCGGGACAGGCTGCACGGCAGCTCGCACATGGAGGGAAGTAGA
CGGAGGCTTGTCGCCCACCAGCGACTCCGGGGACGCAGGGTGGCAGTGCCAGGCAGCTCCGCTGGGCCTCAGG
GGCCCCCGGGAGCCGCTCTGAGGTGCGGAGAGGCTGCTGAGTGGCGGAACTATTCATGCCCTTTCTGGCCGGC
CTCCTCGCCCTCGGGGCTGGGGTCCAGGGACTGAATGCTCCTCTGGAAGCTCACCACCCCACCTGCCCGCGCT
GCTTCTACCTGAAACTGGCCAAGGGCCCGAGCCCGGACCGGAGCCGTGACTTCCCTCCGCCGGCCACGGGGCT
GCCCGGATCCGCCGGGTTATGTCGCTTGGCTTTGGGCTCAGGGGTCACCGTGGGCAGAGGGGGGTGCCGGGGT
CGCGGACTGCCACCAGGTTGAGGAAAGGAGGGGCCTTTTGGCTGGGGAAAGAGCGTGGTGGGGGACCCGCGGC
CGATGGAATCCCTGGGGCAGCGCGGCCCGCACCGTGGAGGTTGGGGAAGCGCCTCGGGGAAGTGTTTCCTGTG
TTCCCAGAAAAGGAAGACAACCGAGAGCAGGTTTCAGGCTTTTAAAGAAAGCCTGGGGTGTGGAGGTGATGCT
CCGCACACGTCTGTGTCTCCTCCCCTGCTGCGGCCGGCTTGGTTGTGCCGGCTAGCGTGCGACCGTCCTCCTC
GCTGCAGGCCGAGAGCGGAGGCGTAAACCCAGGCCAGCGAGGAGTGTCCTATAAAGGGACGGGGACTTTTCGG
CG
CGI: 25 range = chr8: 25955253-25955609
CGTTTGCTCCGCCGTCAGTCCATAACCAGGCGCTACTAAGGCCTCCAGGCTCGGTGCGCAGAGCCGGGAGCGC
TCCTCCAGCTCCAGGTTGGGGGAGTCGGGGTGGGAGGAGGTTCGGGAAATCGACTGATTTAGAGGCTGGGGGT
GAGTAGCCTCGATTTATCATCCCTGATGGTGAGAGTGGAAAAGTGTCGCGAGAGTGACAGATGGAATCTTTAG
TGCTTCGCAAGAGGGAGTTATTAGGCCGCGGGGTTTGGGGGGTACTTTCCGCTTACTTTGTCATTCTCCACAA
AGTCCACGAAGGCCGTCCGCTCGATCTCCACCGGCTGGCCCTGCCTGTCATAGAGCGCCAGGACG
CGI: 233 range = chr8: 55532724-55535078
CGCTCGGTATGTTCATCTAAACGACCTTGGGCAAGTACGTCGATTCCAAGGTACAATCAGCCCTCCCAGACGG
CTTTTCGAGTCTCCCTAACCCCGGTGGGAGAGGACGCGGCGCCAGAGCCCAGCTCCGGCTAGTTTTCCCGGGG
GCAGGTGTAGCCTTGGGCGCGGGGCCGGGGGAGGGGCAAGGGGCGGGCGTGGGGTTGGACTGGGACGTGGGAC
TCGGACCACGGCCTGGGCGTGGGCCTAACGACGCGGGACCGGCCCGCCCTCGCCGCTCCATTGGCCACATCTG
TGCAGAAAAGGCCCCGCGGCCCAGGGGCGCCCGCAGTGTCACTAGGCCGGCTGGGGGCCCTGGGTACGCTGTA
GACCAGACCGCGACAGGCCAGAACACGGGCGGCGGCTTCGGGCCGGGAGACCCGCGCAGCCCTCGGGGCATCT
CAGTGCCTCACTCCCCACCCCCTCCCCCGGGTCGGGGGAGGCGGCGCGTCCGGCGGAGGGTTGAGGGGAGCGG
GGCAGGCCTGGAGCGCCATGAGCAGCCCGGATGCGGGATACGCCAGTGACGACCAGAGCCAGACCCAGAGCGC
GCTGCCCGCGGTGATGGCCGGGCTGGGCCCCTGCCCCTGGGCCGAGTCGCTGAGCCCCATCGGGGACATGAAG
GTGAAGGGCGAGGCGCCGGCGAACAGCGGAGCACCGGCCGGGGCCGCGGGCCGAGCCAAGGGCGAGTCCCGTA
TCCGGCGGCCGATGAACGCTTTCATGGTGTGGGCTAAGGACGAGCGCAAGCGGCTGGCGCAGCAGAATCCAGA
CCTGCACAACGCCGAGTTGAGCAAGATGCTGGGTGAGTCCGAGTCGCAGACCCAGGCGGCCGGGCGCGCTGGC
GCGAATCGCTAGGCCGATTTCTTAAACCCCAAACTGTTCTTTGCGAGCCTGACGCCCAAAACCAGGGGTGTGT
AGCGGCCACGTCCTTTCTTAAGGCTCTGGGTTCCCTTCCCGCTTCCCGCCCTCCGACCCTCCAAAGCAGCTTT
CCGCCTTGCTCTCCGGCTCCCGGATTCCCCAGGTGGCCGGGGGCGCGGGTCCAACGGCTCTGGGAAGGCGACT
TCCCGGCACCTCCGGGCGGCGCGAGAGCACCCTTGGCCCTGAACTGGGCCGGTTGTGTCCATCCCTCGACCCC
TTCCCTAGTTAGGTGTCCTTTTCTGTTTTTCGAACGACCGGGTGATGGGTGAGCGGAAAGCCGCTTCCAGGAG
ACCAAAAGAAAGGGGTGCCTTTAGAGGACGGGTGTTCCCCAAGGGCTCGGACTCAGGAGTCCCAGATCTCCCT
CTTTAACTTCACCCCGGTTGCGCAATTCAAAGTCTGAGGGGGGAGGTGCGTCCAGGTGGGGCCAGGTGGGGCC
TGGAGCGGGAGCGCAGCCGATAAGCCCTGCGCCCCTCTCCCCCTTCCTTCCACTGTGCAGGCAAGTCGTGGAA
GGCGCTGACGCTGGCGGAGAAGCGGCCCTTCGTGGAGGAGGCAGAGCGGCTGCGCGTGCAGCACATGCAGGAC
CACCCCAACTACAAGTACCGGCCGCGGCGGCGCAAGCAGGTGAAGCGGCTGAAGCGGGTGGAGGGCGGCTTCC
TGCACGGCCTGGCTGAGCCGCAGGCGGCCGCGCTGGGCCCCGAGGGCGGCCGCGTGGCCATGGACGGCCTGGG
CCTCCAGTTCCCCGAGCAGGGCTTCCCCGCCGGCCCGCCGCTGCTGCCTCCGCACATGGGCGGCCACTACCGC
GACTGCCAGAGTCTGGGCGCGCCTCCGCTCGACGGCTACCCGTTGCCCACGCCCGACACGTCCCCGCTGGACG
GCGTGGACCCCGACCCGGCTTTCTTCGCCGCCCCGATGCCCGGGGACTGCCCGGCGGCCGGCACCTACAGCTA
CGCGCAGGTCTCGGACTACGCTGGCCCCCCGGAGCCTCCCGCCGGTCCCATGCACCCCCGACTCGGCCCAGAG
CCCGCGGGTCCCTCGATTCCGGGCCTCCTGGCGCCACCCAGCGCCCTTCACGTGTACTACGGCGCGATGGGCT
CGCCCGGGGCGGGCGGCGGGCGCGGCTTCCAGATGCAGCCGCAACACCAGCACCAGCACCAGCACCAGCACCA
CCCCCCGGGCCCCGGACAGCCGTCGCCCCCTCCGGAGGCACTGCCCTGCCGGGACGGCACGGACCCCAGTCAG
CCCGCCGAGCTCCTCGGGGAGGTGGACCGCACGGAATTTGAACAGTATCTGCACTTCGTGTGCAAGCCTGAGA
TGGGCCTCCCCTACCAGGGGCATGACTCCGGTGTGAATCTCCCCGACAGCCACGGGGCCATTTCCTCGGTGGT
GTCCGACGCCAGCTCCGCG
CGI: 74 range = chr8: 72916429-72917309
CGGGGCAAGGGCGCGTTCCCTATCGCAGGATCACTTGCTATGGTAAGCCGCCCACCCTGCGCGCTCCTCCGCG
CGGGGAAGAACCTGCGCGGCAGGACGTGGTGTTGGAGTTGGGGCGCCCGGAGCGTGGAGTGGGGAGACCTGAT
GCAGAGAGTCTGGAGTCGGAGCTGGGGGTGCTGCAGGTAGGAGCAGGAGCGGGGCGGAGAGGGAGGCCCGAAG
AAGACCCCACACAGGTTGGCGCAGCGGGGCTTGGGGAGGCTTCAGCCCAGAAGTGGAGAGGGTTGACAGACGC
CTGCCTGATTAGAAAAAGCCGGGAGCTTGGGAAGGAGACGGGATTGAAGAAGCCACCCGGCAGGGAGGCCGAA
CGGCCCAGAGCTCTCCGGGTAAAACCCGCCTGCGGTGATCTGGGAAGTGTGTCTCCACCTAGCCCTGCGAGCA
GCGGCCTTCCTCCCGCCCGTTAGAAGGGCGCTGTGCTGGAGTACGAACCCGGCCCAGAGAAGCCACTCGCCCT
TCTTTGTCACTTAAAACCCTGTCCCGACGCGGATCTCACGTCTAGACCTCTGTCTTTAAAGCGGATGTAGAGC
GCGTTCTAACCGTTCCCTAACCATTGTGTCACCGCGAAAGGCCGGGGCTGTGTGGAACCGTCCCGCACGTGTG
CGATGAATCTGGCTCCGCTGAGAACGGATCCGTGGGCTGTCTGGCGCGGGCTGGGGCAGCAGCCGAGAGTTAG
TCTACAGAGCTAGGGCCCGAGGGTGGACCTGCGTCCGCGTCTCGTCACGAAAGGAAGCTCTTTTTGGAGAGGC
AAAACGTGGTCGCCCAGATCCGGCGCAGCTGTAGCCGTGGGCGCTGTGCAGTGACAGCCACACCCGCCACCTG
TCACG
CGI: 17 range = chr8: 140700279-140700514
CGGCCGCCCCGATGCACAGCGTCCCCATGCAGGAGAAGAAGCCCACAGTCACCATGTTCTCCATAGACACGTC
AGTGTTGCGCATGCCACAGCACTTCTTAATGCGCTTCAGCAGGTAGCGCACGAAGGTGTTCATGCGCTCGCCC
AGGCTCTGGAACATGACCAGTGTCAGCGGGATGCCCAGCACGGCGTAGAACATGCAGAAGGCCTTGCCCGCAT
CGGTGCCAGGTGCAGCG
CGI: 21 range = chr8: 145014900-145015187
CGCTGACCACCTGCCGCAGGGCCGCAGCCCTCCCAGACCGACAGAGTGCCACCAGCTCCCGCCGCTTGTCAGC
GCCAACGTATTCGGAGAGCAGCAGGTCCCAGAGTGACACGCTACACCCCTTAAACCTCCCTGTGCTGACGGGC
ACCTTCATGGCCCTCAGAGCCACCGCGGTGTGGTCGTCCACCTCAAGCACTGTGTCTGAGGGCAGTGGCAACA
GCAACAATCCGGTCTCGGAGTCGCACACGCAGCGCTCCCTGAGCTGCTGGTAGGTCACCTGGTCCCGCG
CGI: 260 range = chr9: 959530-963276
CGTGTGCCCTTCGGCGGGCGGCTGTAGCTGTAGCTGTTGTGACGGCTACGGCGGAGGCTGCGGCCGCGCGGGG
AATGGAGCCGGACCGCGGAGTCGTCACCTCCAAGGTGTTTCTAGTGGCCTCCTGGAAGATGATCCCGCGCCCA
CCTTGCCGGCGTGTTCGCGGGCCCCTGCCCACTGCCCCCCCTCTTTCTTTAGGTCTGGCTTTTGAGGATCCCG
GAGTCTTGCAGCTCCCGCCATTCCGCAGATAACCTCCGCACACTTAATTGTGACCCGCGGGGTGGTCGGAGAA
GCTCCGCACGCGTCCTCAGTGGGAAAGTGTCCCCTCTCAGCACTGCCCCCTTCAGTCCCCCTGCATTTCTGGA
AAGTCAGGCAAGGCCCAGGTAGGCTGCCAGTGCACTCTCAGCCTTGACTGAGCACCTTTCGGGCCTCTGGTGA
GCCCCGAGAGCCAGGTTTGGCTCGGCAGAGCGGGCTTGGGCTGCGCAAGCAATGCGCATCGTGGCCGCCTGCA
CCCTGGGAACTAGGCCTGTCCAGTGGGCAGCATCCTCATTTTTGAAAAGGCCCTTCTAAACCCACCGGCCTCG
CCTAACGCCGTTTGGTGCTGCATCCGAGCGGCCTCACGCGGTCCCCTGGAAGGGCCACTCCCAGCGGGAGGGC
GGGGCCCGGGACCTGCGCTGGCCACGCAGGGTCTCAAGCTGACCGGAAGACCCGGCTTTTGGCCTGTGTCCAA
TAGCCCCAGAAGAGAGGGGTCTGGAGCCTTCCTCCCACGCGTAGTGACGCTCAGGTGTCCTCGGGTTGTTAGT
CTTGACCCAGGAGAGTGCAAGACAGGCCCAAGGCCTGGGGGGATTGCGTTATGAATGTCCAATTCTAAACACA
AGGTAGAGCACAGACAGTACATCCTCACGGCTGGATTTTAACCGTATTTTAATAAACACATTCGAGGGGGTGT
CAGTTTCCCCAAGCTCTGCCCCCTTCCGCGGGCGGGATCCATGGTGTGTGCAGTGTAAGAGTGCGCAGAACGC
GTGTGTTCAAGTGTGGGCGTGGCAGGCGTCGTGTGCTCGCCCCGCGCACTGTGCGGATCGCCCAGACAGCCTT
GACAGGTTTTTGCAGATGTTTGGGTGCTACGGTGTGGGGAAACCCAGGCAGGAGCGCCAGGCCTAATTCTCCT
GGACTCTTGGTGAGCGGCCGCTACTCCACGAGGGGCTAGAAGCAAAGGGGGCACGCGCTTTTCCCCAGGCCGC
CTCTTGCTGCCGCAGTGGCTGAGGGCGCTGATGACCCCTCCCCGCTTCCAGCGGACTTGACCCGCGGGCTGAC
AACCCACCGCGACAAGCAGGCGGCTGGGTTCGCGCCGCCGCCCCGGGGCCCTTGGCTCAAATTTCACCTCGAG
TCCTGCAGACCCTGCGCCACTGAATTGGGGCCCAGGACGCCCTTGGTGACACTCGCCTTCTTGCTGCCACAAC
CACCGTCATACCCGCAGCCGGGGCTCCCTCCGCTAACCACGCTTGGAGACCCCAATCGGGGACAGAGGTGGGA
GTCAGACCCCCCCTGGCCTGCACTGCCGTTTCCCTCGATTCTTGCGGAAACAAGACTCCCGCCCACACATAAA
AATGCAGCTCCCGGCCACCGGGCGCCGGTGGCTCACGCCTGTAATCCCAACACCTTGGGAGGCCGAGGCGGGC
GGATCACTTGAGGTCAGGAGTTCGAGAGCAGCCTGACCGACTACTAAAAATACAAAAATTAGCCAGGAGTAGT
GGTGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCACAAGAATCGTCTGAACCCGGGAAGCGGAGGGA
AGCAGCGAGTCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAATGAGATTCCGTCTCAACAAATAAAT
AGAAATAAAAATATGCAGCCCCCTCCGCTCCACTTGAACTTTAATGCTGAACCGGTTTCCCACGTATACGTGT
ATCGCACCGCATTTTGACGCTTTGCATCGAGTCGCATTAATGGCGCTTTTGAGAACGCGTCGTCGCGCTTTAC
AGAGAAACCCTACGGGCAGCCTGTGGAGGGGTAGGGGATATTCATTGGCTTTCCCTGCTGGGCCCCGTCCGCC
GGGCGGGTTAGGGTCGTGGCAGCCTGCCCGCGCGCCGCTGACTCTGGAATTTTGTCCGGGAAACTGGCGTAGG
GCCCTGGCTCTCCCTTCGCCCTCCGCGCACACGCGGACGAGGCCTTAGATCCACAGCCTTTTCTAGGCCCTGC
GCCTTTGAAGCTGGGCCACTGCCAACCGCTCGCGATTCTCACCTTCAACAGTCGCCCCCTTACCCCTCCCCCA
CCCGCCTGCCCTCGGGAGCGGGTCGCCTCCACTCCACCACCTGTTTAAGTTCCTCCCCCTCGGCGCCCCTCCA
GTCCCCACCCCGGCCCCGGTCCAAAAAACCAGCAAACGGAACTTTTCCACAGTTGAAAGCCGCGGCCCGCGAG
GCCGGGCTGGGAGGGGAAAGCGGGGCGTGTCTGGGGGGCGGGGCCCCGAGCACTCCGGAAGTTGCCCCGCCCA
GGAGGCTCCTGGGAAAGTGAGGAGAGGGCCCGGGCCTACTTTCGTCCTGGTGTGGCGCCCCTCAGCCTCCCCT
CCTCCCAGTTCCCGCGCCTCCGCAGGGCGCCTCGGCCTGGCCTCCAGGCAAAGTTCGCGCCCCCTGTTCCTGG
GGTGTCGGCCGCGCGGGCCGTTTCCCTTCATTACTCCCGGGCCCCTGAATCCGAACGCTTTCCCAGAAGCGCG
CAAATCCGCTTGCTTTCCCCGCGGCTGGGCTTTGTTCAGGGACAGCAAAGGAGGAGGCGGGAGGCTGGTGAGG
TTTTCTGGAAAAGGGGCTTGTCCCGAGGAGGAAGTGCCCCAGATCCCTGAGAGCCAACGCTCTGGGGAGAAGA
AACTTTCCTTCTCCCTTGAATGTTGCTCAGATTACCTAAAATTATTTTTTCAGCCCTTGTGTTCTAAAGTCGC
AGGGTAAAGGTTATCTTAAGACTTAACATCAGCGCTGCTCATTTGTACGTTGGTGGAGACGTGCCTTTTTTCC
TTTGCACTTAAGGTGGACAGGGTCTGCGACGCTCCCTTCCAGGACGGTGTGGGGAAGCGGCCGACGTCCCCAG
CCGGACTCACGCCCTCCTACTACTGGGCGTCGGCTCCGCCGCGGGCGCTCCCGACAGGGAGCTGGAGTCGGAC
GAGCGGCTGCCCCCAGGGCCTCCAGGAACCGCGGCCCAGCGGGGAGCGCCCCAGGCTAGCGCTTTTCCAGTTC
CCTTCGAAAGCGCGGGGCTGAGGTCGCGGCGCTGGGCCCTCGGATGAAGCCGTGCTGTAGCTACACCTGAACC
CCGCGAAAGGCTGGCGCGGTCGTGTATCCAGGCTGGGTCTGAGGAATCCGCAAGCGGGAGAGCGCTAACTCCT
AGGCGTGAGCCGCTGCTGGCTTCGAGAGTTCGAGAACATGAAGGACCTGGCTTCTCCCGCCCGGTCGGCTTAG
GGCCAGCGAGGTCACAGGCCGTTCTGCTCTCCCTGTTTGTCCCCAAAGGCCTCGGCACGTGGGGATCTGGAGC
AGGCCTCAGGCTGCGACCCGTCTCTTCCCCTACCAAAATTATGTGGGAACAGCGGTCCAGGACCTTCCCCTGT
TCAGCGGTATCCCCGGGCCGGTGACCCCGGGGTTCAGTCGTCTCCCCGACCCCAAGCGGCCTCTGCTTTCCAC
CCCTCGCCCCGGAGGGCGGCTTCG
CGI: 25 range = chr9: 21979774-21980108
CGCGGCCAGTGAAATCCCAATCGTCTTCCACGTGGAACCCCAGGTCCGCAGTTATGATAACGGATCACATCGC
TCCTGCGGAAAGTGCGCGCGGTGGAGTGATAATTGGACCTAGCGTCTAAATTCTTGTTGGAGGACCTCGTTCC
AGCTGCCAGTTAAGCCTCTGGGATCCGCAGCGTCTCTAGGAATTGAGAGAGTGGGGAAGTTAGGATCCAGGAG
GAGGATGGTGGGGGCTGAGGAGTGGAGGAGCAGCGTGCATCTCATCTCTTGTCGCCGGGCGGGCGCTCTTTCG
GGTCCAGGGCCCTTGCACCCCCAGCGTGGCTCCGGAGGCGGCG
CGI: 20 range = chr9: 23812413-23812667
CGACTATGCAAACGCTTGCCGCTAGCCGCATCCTTCTATCGCCCCCCAACTCAAGACCCGAAATGGCCAACTC
TTCACCGAGGGGGCGTCCCATCGCTGCCTTGCCTTGGCCCGCCCCTTCGCCAAGCTCAATCCCTTTTCCCCAG
AAAAACCTGTGCCTGTCCTCAGACCCGGCCCCACGGCTGGAAGTCAAAACCCACCCCGGAGCCACGCGGCTGG
AGCACGTTTTTACACCTGCTCGGCCGCTTAATTACG
CGI: 278 range = chr9: 37024136-37028341
CGCTCACAGGTCGGAATAATTCAAGCCTTCCGCTCCCCCGCCGAGCTGGGGTAGCTGATCACTGAGCTGAAAC
TAAACGTTTTAGGTGGAAAAAAAGCGTCCGAAGGCACCGTGAAATGATTAAGGAACTAAAGAGCTTCTCGCCA
TGTGAGATCATGTCCTGTTCTCGCCAACATCACAAGATGTCCCCAGACACGCCGCGCCCCCAGCGCGCCGCCC
CACACTGCCGGCCCGGAGCGAGGAAAGGGTAGGCGCTGCGCGGCCGGGCCTGCTCAGCGCGCCAGACGTGGCG
GACCCGGCCCGGCCGGAGTAGAGCGGGAAGCCGGGAGAGCAGCAGTGCTGCTGCCGCGCCGCCCCAGACTTTT
ATAGGGGTTGGGGGGAGGGAAGGAAGGCTTCAGCCTGCGCCGGGCGCTAGCCAGCGCACCTACGGGAAGGGGC
AGACCGAAGCGGAGCCCGGGAGCCCGGGTCTTCCAGCCGCACCTTCTATTAAGACATGCGCTTGGGGGTCGCG
GCCCTCTGCGCTGTGCGCGGGGCCTGTGACATCTCCATGTGCAAACCCCGCTGCTTAGACGAGCGCAGGCCGG
GTTTTTGTTTTTGAAGAAATTAACTGCTCGGCCAAGCAGGTGCTTTTGAAAGGGGTTGCAAAGGCTGGCAGTG
TTGCCAGGCACCGAGGCGACGTTCCGGTTTACTCCGATTCACCCCTAGGGCGGCGCCCGACCCCAGGGTTCCC
AGCCATCCAACCCCCACCCCAATTTGTTGGGGTCCTGACTATTGCTGGGCCCCTGACCCTAGGGCAGCGCCAG
ATCCCTAAAGCCCCCAGGTCCCATCCAGTCTTCTAGTCCCAGAACCCCTCCCCACATCAAGTTCCATTCTGGC
CCAGAGCATGGAGGTTAAGCTGTGAAATACTGGAGATGAAATCCGGGCTTCCGCTTTGGAGCACCCGGGCAGA
GCAGAACATCTCAGTAGTTTCTGGAGATTGGCGGGAGTTCCAGACACCTTACCCCGGCCCATAAGTGGAATCG
CATTGCCCTCGAGCCCTGAGACGTTGTGGAGTCCCAGAGCCCCAGGACTTGATTCCAGAGAGGAAATCAGATC
CACAGAGACCGAGCAGAGGTGTGGCATGTCCAGCCCTCTCTCTTCGGGCCAGACTCAAGCCTCCCCTCCCTGT
TCCCCTCCCCAGCCTTGAGTTAGTTCAGCTGCTGGGCCTAGCCACTGAAAGCCTGTGGGGCCCTGCAGCGGGG
TGGTCGCAGGGGAAAGGTTCTCCAGGGCGGGGGAGCGCTCCGTAGGAGGACTCCTGGCCCGCCGGACAATGGC
AGTTTTGGAGAGTGAATCGTCCTCAGCAAGAGTGTTGTTTGTTTTTTGGAGGGGGTGGTCACGAGGCTGGGTC
GCAACCTAGGGGGAAGAGCCTAGAGCTCGAGGAAAGGGGGGCCCCCGGCGGCAACTGGACATCACATATCCAC
TGAGCAGATTTCGCCACAATCGGAAATGTGGCTGTGGATTCCCGGGCGGCCCCCCCACCAAGTGGTCTGCGCA
GTTCCCCAGCGCCGCCTCCTCCCTGCAGCCTGCGGGCCCGTGTCCCTACCCCGAGATTTGATTTTTGGCCATC
TCCGAGTGCTCGACTCTTTCCCTCCGCAGCCCAGCCCCAGCCCAGGCTTCCCGCCCTCCCGCCTCGCCCGCGC
CGGGAGGCAGCGCCTGGGAGGAGCGGCCTGTCCGCGCCTGGAGATCAAAAGCCCTCCCGGAATTGACATTTCA
CCCCGGGCTGGGGGCGGGGGGTGTTGGTGTTTTGTTGTTGTTGTTGTTTCCATTTAGAGGGCTTGTTTTGTTT
TTGTTTGTTTTCTGTGAGTTTTCATTTTTCCATGGGATATTCTTTTGTTTCGGGTGTTTTGCGTGTTGTTTTT
TCGTGGGATTGATTTTAGCGGGTTTTGCTCTGTAAGTCCTGGTCTTTGGGGTGAGTTTTGATTTTGTGTAATT
TTGTACTTTGTCCTTGTAGGCTGTCTTTTTGTGTGTCGTTTGTAAGGCTTTTCCTTCTCCGCGGTGTTTAGAT
GTGTTTTGATTTGGTGTGAGTGGGTGTCGTCTGTGTGTGTGTTGCCTTAGGGAATTTCGTGTTGTGTGTGTTT
TGTTTCCTTCGATTTGAATTTTATTTTTTTGAACTGTACGTTTTGGTGGGGGATCGGGTTATATTTTCATGTG
TTGTCTTTAGTTTTTGTGTTTGTGAGATGCGCTGGTGAGAGTTTGCGTGTGTATTTTGGCTTTTGTGGGGCTT
TGGGATTAGGGAGGGGACATCAGCCGCTACTCCGTTCCTGCCCGCACCCATGAAGGGCAGAGGATTAGGCCAA
GCATCACGAATCGTAGGTTCGCCGTGCTCCGCCGCTTCGCGCTCTGGACGCTCGAGACCAGCGGGAAACAAAT
GTGGTTCCCGAGGGGGCGCCCGCTGGTCGTCAAAACCTCGCGGGCCCGGAGGCGCCGCTGCTGGGTCAGAATC
GCAGAGCCCCCCTCGCGGGGTACCGAGGCCCAGCCGCCGTCCCCTTGCCCACCCTCTCCCCTGTGAGTCGGTC
TCCCCTTGCGCCTGGCCAGCATGCTTCGGACCGTCCGGACTCCCGCAGCGTTGGCCCAAGGGGCGGCTCCCCT
CGGCGGAGCAGGTGACGAACCACTTCGGAGGACACGGAATTGACACTGCGGCCCTAGAGATACGGGACAAGGG
GCCAGAACGCGGGGAGTCTAGGCTCAGATCGGAGTCGGGATCCCGGGAAAATCCCCCATCTCCCTTGCCCGCA
GCCCTAGAATCCCAGAAACCCAACTCCGCGCAGCTTTCGGTTTGGAGAGCCCGCCCTGGTTTGCAAGCACAGA
TACATGTGCCCACACCCGAACACACGCAGACACCGCCAGAGAGCGAGACAGCGAGCGGGCGCCTCCGTAGCAG
CGGCCTGCGGGGCGGAACCGGAGCTGGCGCCGCCTCAAGGGGAAACCGAACTGTAGTGACCGGAAATGTCCCC
AGGACAGAATAAGCCATTCCTTCTGTCCACGTTGCCAGGACTTCTCCAGCTCAACACACCTTGGTTTGTTTAA
TGTTACACGAGGGAGAAGATTTAGAGGCAGAGACACATGCTGGCTCAATCGGCGAGGAAATACGAGCAGAGTC
TAAACAGAAAGAAATATGGAACGGGGGGAGACTAGACTGTGGGGAAGGCAAATTGGAGGCCCAGAAAAGGGGC
TGGTGCGGAAGCTCCTCCAGGCCCCTGGGCGCTCTGGCATTCTGTGAGAAGGAGAAAGCAGAAGCCGAGAACA
GAGAGTGACAGGAAAAGAAAAGAGACGCAGAAGGGGTTGGCCTAGGCACGCTGCGAGCTGCCCTCCAGCTAAG
ACGCTGCGGGCAAGGGAGGGGGAGGCCGACATCGCCAGGCGAGGGGCCAAGGTCGGGCTCTTTAACTCAGCCA
GGAAACATCGTTGGGGGCTCCAGGGCTCGTGGAGCCCGAACTGGGGCTCATTTCCGGCCCGATGCCCCTCTTC
CCCAGACCCCTAGCCCGGAATCCAGCAAAGGCTGGGCCATCGCCGTCCGCCACTGGGCCTCCCTCTGTGCGAG
CCCTGGGAGAAGCCTCAGGGAACGACTCTGGCACTGGGGCTCGGCCCCGGAGCTAGCGCAGAGCGTGGGTGGG
AGTCGACATCCAGGCAGGAGGCAAAGAAGAGGCCCCGCCCTAAAGCCGAGGGCCCAGTTCTTCGAAAGCCTGT
GGCCGGAGCTGGACTCACAGGATTCGGGGTCCGTACAGCGCGCACGTGGTACCGCATCTTCGGCAGGCGGCGC
CCCTAATGCCCAGCCCCGCCCTGCTTCGTTTGCCGGGCCTGAACTGTGTCAGCATTGAGGGTGGACGCCGAGT
CGCGGCGAGTTGGTCCCTTGCGGTATAAACTTGGGGCTTCCCTAGGGGCGGTGCCGGGATGGATGGGGGCGCC
TCTCCACCTGCAACTCCCCCAGCGCAGAGCGCAAAAAGTGCACATCGCGGGCCAGCCGTCGCCTCGGGGTTTC
AGGCGGCGCCCGGGGCAAAAAGGAGCTGAGGATTGGTTTGGGTCAAAACACCCATTTCAGTTGGCAGTGGGGT
CCTCTGCGCCTACAGGGCTTCGAGCTCCGGGTGCGGGCTCACTGGGGCACCATGTGCCAGCGACTCGCCACCC
GGAAATACTTGGGTTGCGCTAGAATACGCAATGGGTCTGTGTTCG
CGI: 392 range = chr9: 101621613-101627382
CGGGCCGCCACCGCCGCCTCGGCTCCTCCGTGACGTCCGGGAAGGGTATCCCCGGCACTCAGGAAGTGGTGGC
CGCGGGCAGCTCCGCCCCCACGCGACTCGGGGCTGGCCGAGCTGCCGGGTGGTAGAACCGCCGGGCCTTCCGC
AGGGCGGGCGGGGATCACCGTCTCCCCACCTCCGTGCGCACACACATGCACGGGCCTCGCGCCCCGCTGTCGC
CCGCGCCTCGCCCTGCTCACTTCTCACAGCCCGCGCCGGACGAAGAGAGCCGCCAGCGCCCCCCCTCTCTCCC
ACGGCTCGCACCCACTCACCCCGACCCCCGGCGCCGAGCCCGGCCCCTCGTCGCCGGTCACCAGACCTGGTCG
AACCGAGTCCAAGATGGCGACTCCGCCCCCGCCCCCTCCGCACTCCCGGCGGGGTCAGGGCGCCCCCTCACGC
GGCGGGCTCGCGCCCGAGACCCGGCTAAAAATAGCCAGGCCCGACTATATTTGGTTCGGCCGGATCCTGGCGC
GGCCGCGCGCTCCCCGCCCCGCCCCGCCCCGCCCCGCGCGCCCTGCCCCGCCCCGCGCGGCGTTGAATGGAGA
AGGGGCGGGGGTGACCGAGGGGAACCTACTCCGCTATCTGCGGCGCGCGCCGGCGGCGGGTCCCGGCCAACCG
CCGAATTTAGTAACATCGCCTGCGTCAATCACGCGCCTCGCGTGCGTCAGCGCCGCGCGGCTCCAGGTCCTGC
TCCCCCCCTTCAAGCCTTTGAATGGATACAATGTAGCAGCGCCCTCCTTCCTTCCGAGGCTGGATTGGAACCC
GCCGCAGTGCAGAGACTCGGTTGCTCTCGGCTGGGTCAACTTTCGGGGCATTCTCCCACGATCCTCTCCGCAC
CACCGTGTCTGAATTGGAAGTGGAGGCGAAGAAAGATATACATGCCATATTTACCTATATGTAGTTTGTTTTC
AAGTTTCTGGTCCTAGCTCGAACCTTCTTCGATTCTGAAATGTGTGCTGTCTACAAAGGAATCTTGTATCTCC
CCTCGGCGCAGCGCCCCCCGCCCCCGCCACACACACACAAATTGGGACAGGTCAAACATATAAAACGGTATTT
GTGATTCAAGCGGACCACATGGGGACCACTCTATCTGCATTGTTTCACTCAAATATTTTCTCCTGTCCAAAAA
TTCATTTCTGAAAGAGACTGCGTTCACTCAGCAGCAACCTTTGGGACTAGGGGTCTTTAACTCTGATAAATTT
TGTTTTCATCAAGAAATTTACACTTAAATTTATCATTTCCAGGAAGAAATTGCTCTCCTTCATACAGTCACCC
AGGCTTTCGGCACACCATTTCATGACAAATGTGTCCGAGGAGACCAAAGCAAATCCCCTAGCGAGGGACTGAC
TAATAAGTCCTGTTGATTGATTTCGAAATGTTTAATTTGGGAGATGTGGGCGGAGGGCATCTACAACCATCAA
AAAGTGAAAGTGCTAGTTGAGAGTTCCATTTCTGACCCGGTGCCGGGGAGGAGGAATGATTTGCAATAGTCAG
ACCCGCTCAGCTGTTCAACACGTGTGTGTTTGTTTTACACACAGAGTAGTTTCTGCTGCAGCGCGCGTGTGCA
TGATGGATGTGCACTTCGCTGGGTTATAACGTGTCCAGTTAAGAAACCCACGCCGTACGTGTAAAGAAATCAA
ACCTTATCCCCGGAACCATCTGCATCCCTGTGTGAAACACGCACCCAGTAAATGATGCGGGGAGGGGGGATTA
GCCTGGGCGCAGAGGACCGGAGCAACGTAAACAGCTTTAGAACCTATGCAAGAGGAAAGTGCAGCTGCACCTC
AGGGCGTCTTCGGGCTGGTGCCAGACGCCTTCTGCACCGGCTGCCAGGTCACTGGAGCTGGTCAGAAGCTGGC
TGGCGGAGCCTTCCCTTTCGGAAGAGCTGTCCTCTCCCTTACCCCCCTCGCCCTGGCTCCGTGCCTCGGGGCA
GCCTCGGAGGCGCGCCAGCAGCACTCCTCCAACTCTACTCCACCCGAGCCTGACAGCTGGGCGGTCCCGCCTG
ACCCGTGGGCAGGCCGCTGCACCCTCCCGCAGACGCACGCCCTGGCGAGCGGTTCCGCTGCAAAAAGAGAAGC
CCCCAGGCCGGGGCCGGCCGTGCGGCGGAGTTTCCATTGTGCGGCCGTGCGACTGGCCGAGGAACGCGCGCGC
GCGCGCGCGCACACGAACACACACACCCTCCCTCGCACACGCGGAACCGGCTGGGCCAGGGGAGGGAGGAGGA
GGGTGACGTAGCGTCCCATGGCGTCACATTGACGTCTCGCATTCCAGGCACTCTATGGAGAGGCCGCTAGGGC
TCCTGTGGCATAAATGACGTGCCGAGAGAGCGAGCGAACGCGCAGCCGGGAGAGCGGAGTCTCCTGCCTCCCG
CCCCCCACCCCTCCAGCTCCTGCTCCTCCTCCGCTCCCCATACACAGACGCGCTCACACCCGCTCCCTCACTC
GCACACACAGACACAAGCGCGCACACAGGCTCCGCACACACACTTCGCTCTCCCGCGCGCTCACACCCCTCTT
GCCCTGAGCCCTTGCCGGTGCAGCGCGGCGCCGCAGCTGGACGCCCCTCCCGGGCTCACTTTGCAACGCTGAC
GGTGCCGGCAGTGGCCGTGGAGGTGGGAACAGCGGCGGCATCCTCCCCCCTGGTCACAGCCCAAGCCAGGACG
CCCGCGGAACCTCTCGGCTGTGCTCTCCCATGAGTCGGGATCGCAGCATCCCCCACCAGCCGCTCACCGCCTC
CGGGAGCCGCTGGGCTTGTACACCGCAGCCCTTCCGGGACAGCAGCTGTGACTCCCCCCCAGTGCAGATTTCG
GGACAGCTCTCTAGAAACTCGCTCTAAAGACGGAACCGCCACAGCACTCAAGTACGTATGAGATTCGCCCAGT
TAATAAGGGGACTTGCTAAAAAAGTTGGCTTGCTGGGAAGCGTCGCTCCTGAAATTGACAACTTTGAGTGTGG
GGTTCCCTCCCCTGACCTTGCCGCCCGGCTCCGGCTTTGCTAGCCCAGCGGCCCGTAGGTTCTGATCTGAAAC
TTTTCCCCTGTAGTGGGCCCGCGGGGATCTCTGGAGCTCGTGGGATTCCTCCCCCCACTCGAAGAGGCGAAAA
GCCTCTAACAAAGAGGAGGACCGGGATTTGTGCTATAGCGGCTCCAGCGATGTAATTCAGGGTATTTCGGCTC
TAGTTGTCATGGTAATGATGCTCTCGGCGGCGGCGGCGGCGGCGGCAGCGGCAGCGGCAGGGAGTTGCAGCTC
CGGTGATGAACGGCAGTAATTTTCCTGCCTTTTAAGTAGGATTGAAAATAGGAGCTCTGGTGGGTCCAAGTAA
ATGTTGCTAATGGTGGCACCGAGCTGGTTCTCTGGAAGGAAGCTTAGGAGGGAAGGGCCTAGGCAGCGACGGC
CAGAGTTTGCAGACGCACTCGGAGGACCTCAGGAAAGAGGGCGTAATTGTAGGAATGTGGCTTATTGTATTGA
AATGAGCCTGGGGTTCCACTAGGCACGTCTGCCTGTCGTCGCTGACATGCCGGTTTACACTTTTCCCTTAGGA
GGTAAATCGGGTGTAATTGGCGACTCCCGCACACTGACACGTGTGGGGACGGTGTCCCTCTCCTCTGGACGTT
GGCTCGGTGTGGGAAAGGCATGCTTTTTCACGGACAGAACTCGCGCTTTTGGAGAAGTTGCTCCGAGTGTTTT
ACTCTTAGTAGAAATGAAAGTTCTCGGTGGTGAGACGAGAGCGGTCATGCGAGCGCAGCCTGCGGAGACTGAC
TTCCAAAGGCACCTCTCCAACCTGTTGGAAGCCTCGGGGCAGTGGTGAGGAAGAACGCATTTGTCCCTTGATT
TCCAAAAACGTTCTTGGAGATTGCCTTTTATTTATTTATGCGTCCGGATTCTCCAGAGGGAAGAGCTGCGAGG
AGTTAGTAATCAGAAATGTCGGGCTGTGATCCCAGGGCCTTGTGGTGCTGGGAGAGAAGAACAGGGAGCCGTC
ATTCCATCGCGAGTCCAGTGCCGGATCTCCTTTTCCCACGACCGGGAAATATTTTATAGAATCAAGTTAGGGA
AAGAAAAAGCTGCCTAACGTGGCTGATGGGCACAATGAATGAAGTTACTTTATTCGAGTTATTTTCGCTGAAC
AAGATGCTCGCAGAGTTAGTATCAAAGCCTCCTTAGGCCACAGCAACCTCCACGTCCGCTCCGCCCCCCACCC
CCCGGCACCCATCCACCCCTTTGCCTGGGACCGTGCGCTCACAGAAATTCTTCCCCGCGGTTTGTCTAGTCTC
CCTCGGTCTTTCTGAGAATCTCAGTCTTTCCCTTTCTGTCAGTCTCTCCCTCGCTCCTCTTGCCCCCGCCCAA
CCTCCGCCCCCGCTCCCCAGGGTTGGAAACTCCGCAGAGGAGCCCCGGTCACAATGGTGCGTTTCACGGTTTC
CTCCACACACTTCACCACCGGGAGGGGAACACGGGGGTGTTCCTTTCGTCTGCCCACGAGAAAGAAAGGGGCT
TTGACAGAGGTAGTTATTTCTTCCTAATTTACAACCCCAAGGCTCTGTGCTCCCGGCCCCGGCGGCCGCAAGC
AGGAGCGGCGGAACGTGTTTCCAGGCACTGAGGCTTTGCCTAGGTAACCGGCCGCTTGTGGGGTGGAGAGAGC
GGCGGGGCGCTGGGCTGGGCTGGAGGAAAGGCTGTGTGGGTCCCTCCCGCGAACGCTGGGCGCTCGAGGGGAA
CTCCTTCGTTGGGGAGAGGCGGTCCCCGCCCACCCGAGTTCTGAGGCCTCCTCTCAGAGAACGACTCCGCTTG
AAAGGCCCTCAGGGAATGCGGGACGGGAATGCGGGCACCCACTGAAGGGGCGGGTGGGGGATTGCTGGAGACC
CCCATTGAAGATGCGGGGAGACGGGAAGCACGTGCTACAGCCGTGGGAAGATCCGCTTCTACCCGCGCTACAT
CGAGCGCAAGCTTTCCGTCCGAGCAGCTCCAGCTGGGGCTGGGGGTGGCAAGGGAATCCCCCATTTCCTGGTC
GTCGAGGGTTTCCTGGACCTGGGAGCCCCGAGTCCCTTTCTCTCTTCCTGCAGGCAAGCCCCGGGCTCAGGGG
CGCCAGGAGATGACCCTCGTGGCCCCGCGCACCTCGGAGGTTTTTGGTTTGGTTTGATTTGGGGTTTTTCGGT
CCCTGTTCCCACTCTTCGAGCTGCGCCCACCCCGGGCAAAGGGGGCGCTATAGGCCGGAGTTTGGGCACCCAG
TTCCTTCCCTGAGGCCTGCTGAGCTGCGCTTTCAGCTACAAAGTTTCGCTGAGGCTGTGGGCTGAGACGCTGG
TCCCGGAGCTGCGCTCGGCGCCCTCAGGAATGTGCCCCCGCTAGGCCGCTGGGTGGCCAGGAGCCTCCAAGCC
GCCCACCCTCGAAGACACCGCCCTCTGGGTGCAGGGGACCTGCCTCCGCTCGTCCCATCAGCCGCTAACGCCG
TCCGCTTCGTCCCCTTGCTTCCAGCGCCAGCCTTCTCATCGCTGTGCCCTTTTGTTTGCTTGACCCCTGGCCC
TCGAAACTCGCGGCTAATAGAAGCGAAGCTCCATTAGCATTTAGAATGAAAAGCGCAGACTTTCTTAATTCCT
CGGGGCATTCATGCATTCGTTCCGGACCTTGTGCATTTCCTATGCAACGTGTAAAATTTGTATTTGAGGGGTG
GGGGCGGGCGGAGCTGGAAAATGGCTTTTTTCCGCTGGTGAACACTCACTGACCCCCCGTATTCGGGCGGAGC
TCG
CGI: 56 range = chr10: 13556172-13556753
CGCTGTTAGATTTCGGGTCAATATCCATCATCGCTGTTAGACTCGGGGCCGACATCCGTCATCGCTGTTAGAC
TCGGGGTCGACACCCATCATCGCCGTTGGACTCGGGGCTGATACCCGTCATCGCTGTTAGATGCGGGGTCGAT
ATCCATCATCGCTGTTAAATTTGGGGTCGATATCCGTCATGACTGTTAGATTTGGGGTCGATATTCCTCATGA
CTGTTAGACTCGGGGCTGATATCTGTCATGACTGTTAGACTCGGGGCCGATATCTGTCATCACTGTTAGACTC
GGGTCAATACCCGTCATCACTGTTACACTCGGGGCCGATACCCGTCACCGCTGTTGGACTCGGGTCGATACCC
GTCACCGCTGTTGGACTCGGGTTGATACCCGTCACCGCTGTTGGACTCGGGTCGATACCCGTCACCGCTGTTG
GACTCGGGTCGATACCCGTCATCGCTGTTGGACTCGGGTCGATACCCGTCATCGCTGTTGGACTCCGGTCGAT
ATCCGTCATCAGTGTTGGGCTCAGGTCGATACCCGTCATCAGTGTTGGACTCGGGTCGATACCCATCATCG
CGI: 22 range = chr10: 15294605-15294858
CGTTAGAGCATAGCGACATCACGTGCGGTTTCTTAATGTCCCTGGTGGCGGATACGCCGAGTCCTCGGAAGGA
CATCTGGACACCACTTTCAGCCACCTCCTTGCAGGGGCGACATCCGCCAAAGTCATCCTTTATTCCGAGTAAT
AACTTTAATTCCTTTCTAACATTTACACGGCAAACAGGAATGCAGTAAACGTCCACGTCCGTCCCACGGCTGG
GCTGCCGTTCCGTTTCCTCCACGAACGGGTACGCG
CGI: 987 range = chr10: 76825135-76839606
CGCTCCCAAAGCCACGCGAAAGTGGAAGCGCGGGGCCTCGGGATGCCCATCCAGCCGGCTGCCCGCGCGCTGG
CCGGGGTTCCAGGACTCCTTCCTGCTCCGCCGGGCTCTGCAGCGCCGCCTGGTGGACACGCGGCGCTCCGCCC
GGGCTCCAGCCGCCAGCCGGCGCGCCGGGGATCCCGCGGCTGTTCGGGAAAAAGCTGGAGAGAGTCGGGGGGC
GCGCCTTGGGGAGGGGCATTTGTCCCTCCGAGGAGGCTCGCACCTCGGCCTGGACACGCAGCAGATACTGGCA
CCCACCCTTCACTTACCGCGCGCCCGGGGTGACTCGGATCCGTCCAACACGTCGGGGAATCCTTTCTGTCCTC
ACCCCCGGGCGCCCCAGCGCCGGAACGCTGCTGCCTCTGTGTAGCTGCTCCCGGAAGGAGTTTCATCAAACTT
TTAAGGGGCTTTGGTTTTGGGTTGTGTTGATAAAATACCAAGAAGGGGCATGAAGGCACGAACGTCCCGGGTT
CGTCTCCCTGCTGGTCCCAAGCCTGAATCCCAGGGCGGGGGAATGTCTAGGTCCTTCCGGGCCGGCAAGGTGT
GGTCGCTCAGGGACCCCTGTCCGAAGACGCTAGGGAAAAGAGGCACAGCCTGTGGGTCGCAGTGGCCAGGAGC
GCGTGGCCGCTGCTGGTGAGAGAGTGGTAGACGCCTGGCTTTCAGGTCCTGAGCTGCGGGCACCGGAGCGTGG
GACCCCGGCTGCAGCACCGCCACGCGCTCCCGCCCTCCCACCTGCAGGGCGGGGGATGTCTGTCCAAGAGGCC
GGGGCGACAAGCCCGCCGGCCAGGATTCTCAAGGAACCAGGCCCAGCTCAGCCTCTCTCGGCGGGACCAGAGT
GGGACCGGGGCCGCGGCGTCCGAAGACGCTGCGGGCCAGGGGTCCTCCTCGGCGCCAGCTCCGTTTCCTGGGG
TCTCGCGACGTCCGGACATCAGGGTCGGGGGTGTGGAGACGGCGGCGGAGCCAGAGTCCCCACCAAGTCAGTT
CCAGGAGGCGGCCCGCGCGCTTCCCGCAGTGTCCGGGAGGTCGCTGGGGGTGGCTTTGCGTGCAACCCGGGTA
AAGGCCCTGCAGCCGTGAGGCTGGCGCTGGGAGGAGGGTGGAAAATCTCAAAGTCACCAATCCCGGTGCAAAT
GGCGGCAGGGGCCGCGGGCTGTCGGACGCAGGCGAGAGGCCAAAGGCTGACTTCGCGCGGCCGTGAGTCCCCA
GAGGCAACAGGGGTACCTGAGCGCCGAGGGGATCCCGAGACTCGGAGAAACCGGAAGAGCCTGACCCCAGGGA
GCGGAGAGTTTGGGGTGCGCTCTCAGAGCTGTGACTCCACGGTCCCGGAATCCTTGGAAAGGGCGCTCTGGGC
TCAGAGCTCCCAACTAGCCGGAGGACCTGGGCTAGCGCCCAGGCCTGGAGCGTCTGGGAGGGGGCGCTGGGTC
TCGGCCCCCCTCCCCCCAAAAGGGACTGAGACTTTTTTCTGCGTGCTTCCTTCGGCGCTTCGGGCAGCTCTGT
CCTGCGGCCCAAGCTGGGGAGAAGACAGCGGCCCGCGCCACAGGGAGCTGCGCCCGGACCCAGACTCCCGCCG
CGCTTCTGCAGAGCGGAGCCCTAGGTGCCCACCTGGTAGCCCCAGAAAGGCCGGACCTGGGCGCCGGGACGCT
CGCGGGGCCGCACTTGGAGGGGCTTTCCGGGTCCTGGCCGGGCGGGCTCTCCTGCGGCGCGGAATGGAATAGA
GCGCCGGCTGCAGAGCCACCCGGACGGGGAAAAGCAGCGGTGGCGCCGGCCAGCCCCGGGTCCCGACTCTGGA
GGGAGGAAGGAGCGGGCGGGTGGGGGTGGGGGTGAGGGCGAGGGTTGCGGGGAGCGTTTAGAAGGCCCTGGGC
AGCCAGAAGAAGAAAAGAGGACGCACTCTCCCCTAGGGACCAGAGGGTCCCTGCGTACTCCCCCCAGGCCCGG
GACACAGGTTCCCCCAGCGCCCCTCCGCCTCCCAGTCTATTCGGCTTGCCCCAGCGCGCTGCCCCACGTCCCC
GAGGCCCCGGCCCAGGCCCAGCCGGCGAGTCCCGGCCTGCTCCACTCTGCACAAAACGAAACCCAAATGCCCA
AAAAGCTCAGGAGGGAAATTTAACAAAAACCCTGTCCCCCGCCCCACACCCCCTTTCACTTTTAACAAGCCAG
CTGCCAAGAGAAAATTGAAATAAAAACGAAATGATAGATAGCGGAGGACACTATTTTCCAAATGGTGAAATAT
CCTCTAAAAATATGTTCCCCAAGGCCAACTTCGCGGCTGGTAGCCCCTTCCGACGCCTTTGCCTCCCAGAAAA
TCACAACAAAGCGATCGGAAATTCAGCCACGGTCCCGGGAAGAAGGAGTAGCAGTGAGGCCCCGGAACCCACT
GCGGCCGAAACTGCCATGCTCTCTTTAACCAAAATAAAAAAGATAAGAAGAAGAAGTAAAACCCTTTAATACA
TCAAATATACGGAATTTTAATCTTTAAAGCGATACATTGTCTATTATTTTAGTACATGACGTAAACCTTGTCC
CCTTCTCAGCGGGTGGACTTAAAAATTAAAAATAGTTAAGTGTTCCTTTTAAAGAACAAAATAAGGCAAATGA
GGTTTTGGAATAGAATTTTTTCTTTTTCTTTTTTTTTTTGTTGTTTTCTTCCAGAATACATACAAAAAAATAC
CCATTCTCTTCGATGGTATACACCTTAAAAATAATTGCAATTTGAAATCAGAGCTGACAAATTGTGACTTTTT
TTTTCATTTTTTTTGTAACAAACATGCATGTAAATTTGTGTTTCAATCAGACATTAAATAACGTACAATACAA
TCATAGCAATTTTAAAGTAACATTAAAGAGAAGACCTCTAGTTCTGTGGCGGTTTTGCTTTTATTTATAATCT
ACAAGGGATGGGAGGGTTTGTTTTCCACATTTTTACCCTCAAGTTTTAAAATTTTTCCCACCTCCTTTTTACC
TACAGAGCTCAAACTAAATAATGCACTTTTGAACCACCGGTCCGCTTGGAGCTAACATAAATAAATACCAGTG
TCCACCGATGCAGTCCTCAGATGAACACTTTCTCAATTATTTTTTCCTTTTTTTTTCTATAAAAAGTCAAATG
ATATTTTTTCAACTTTTATAAAGTTTGGGTGGGGAGGTGAAAGTGGGGAGAAGGGGAGTGTCCCACCGGGTCT
CGGTCGCTGCTGTCGGGTAGATAGATACGGTATACATTTCTTTCCTTTCGTGGCCCGAGTCCTCCCCACGCGC
GGGTGTCAGCAGCCTGGGCCGTGATCCCGCCTCTCCCTGGACTCCTCCCCTCCCCCTCTCCCTCCTCTCCCTC
GCTCGCCCTCCCGGCCGCCCTCACTGATACCCCAGCGCCGAGGCGGTGGTCAGTCTCTGTCCGTAGAGGGCGT
AGGGGGAGTAGTACGGTCCGGTGGCGGCGGGCACCGGCACGGGGGCGCCAGGCGTGGGAAGCGGGCTCTTGGA
GTAGGGGTGGTAGCGGCTGCTGAGTCCCAGCGCGTGGTGGGGGCTGCGCAGCGCCAGCGTCCCAGGGCTGCCC
GGTGCGCCCGAGGTGGGGATGTGCATGTGGCAAGCCATGGCGGCCGCGGCAGCGCTGGCCAGAGACGACGAGC
TGGGGTAGCCCGACAGCAGTTTGTCTGTCCCGGGAAATGCCGTATGGGTCCGCAAGTGGCTCAGCAGCTCTTC
GGACGTGGCGAAGCGCTTGTCGCACGGCCCGTTGGCCGACACCCAGTTGCAGATGTGGGGGAGTGGGTCGTTA
GGGAGCATAAAGCCGTAGGGGTAGAGGGGGTGGCCGGCCAGGGAGGGCGGTGTGGCGCCAGCAGCCGCGGCGG
CCGTTAGCGAGGAGTGCACACCGTGCAGCGGGTGCGTGGGGTACACCAGCGGGTATCCGGACTTCAGCGCCGC
AGCCGCAGCAGCCGGATCATGTGCGCAAGAAGCGCTGGCGGCCGCCGCCCCTGCCAGGTGGCTAGCGCAGTGG
TAGCTGAGGCAGTAAGGGTCCCGGCACAAACTGGCTGTCATCACGGACGGCGGAGACGCTCCGGCCAAAGGGC
TGGAGCCGGCCGGCTTACTGCAGCCCAGAGACCCGGCCGCGGCCGCCGCCAGCTGCGCCCCCACCAGGCTGCC
CGGCTTGGTGGGGTCAAGTGCCACGCCGTGTGGCAGGAACTGGGGCGGGTAGCCGGCGTAGGCCCCGGCCAGG
CTGCCTGGGTAGGTCATACCCGCGGGAGGCAGAGGGAACACTGTCTGGCCCGGCTTGTAGGGTGACACGGGAG
CCACCAGCCCAGAGCCCAACACTGAGGAGGAGGTGGGCGCGCTGGGGCCGGAGCCGGAGCTGGAGCCCGATGA
ACCGCCGCAGTCCGAGCCCAGAGCCTTGCCTCCCGGGCCCCCATCCGGATGCTGGTTCACATCCACATTAATC
CCGCCGCCGCAGCTAATCCGGCCGTGTGCCAGCCCCGTGGGTCCCCCTTCGGCCGAGGCGCCCCCGGTGCCCT
TGCCACCGCCGCCCACGTCGGTGTCTTTCTTGTCGTCCTTGCCCTCCGGGGCACCCCCGGCCGAGGACAGCAT
ACCTCCCGGCGAGCAGGCCGAGGCGCTGGAGCTCGGGCTGCCTGTCCTGGGCGTGAATGGCTGGCAGGTGGCG
CTCGGTACCCGGAATCCCGACTTCTCCGACGAAACACCCCCGCCGCCGCCCCCGCCACCGCCACCGCCTCCAC
CGCCGCCTCCCGGCTCCTTCTTATCCGAGCCGGGTTTGGAGTACGGCTTGAAACTCGACTTGTCCTCCACGCC
GATGTCGCTCAGCTTCAGGGGGCCCGATTTGGTGTCCTTGTCGCCCGCAGCACCGCCGCCGGCACCGCCCGCG
CCGCCCCCGTTGGAGGCAACCGAGGAGAGTTTGGAGGAGGGCGAGGGGTCGGGCTTCCCGATCTGCGAACATG
TTTGCGCCAACAGCGCCAGCGGGCTCTTCTTGGCATCGAGCTGCGGGGTCAGACGATGGGGGGGGAGCGTCAC
ACAGAGAAAGAAGTGGAAACCCTTTAGAATCCTGGCTTCTGGGGTTCAAATGCCTCTCCGCAACAGCCCACGA
AGATCCTCCCAGCCCCAAGGCGCAATTCTAGGCGGCACCCCCTCTTCAACACCCACTCACAAACATTCTCGCC
GTTGGGAAAGGCAGCAGATTGCTCCCCCCGCCCAACCACCACCCCCAGCAGCATCTTTCCTGCCCTCTCTGAG
CGCTAACTAGATTTTTAAAGAGCAAAATGTTTTGGTTTTCGGTTCCTAGACCCAGAACTGTACCCCCTCCCCA
CAAACACTCCTTAATTCTTCAGAGTAAGGGCTCGGGCGGCTGGCGCCTCAGAGGCTGTGTGCACACACTGGCT
TCTGCGGATACGAAGGACGGCGACTTTGGAACCGTATTTCAGACCTCCGCCTGCCTTCGGTGCCGAGTGAAGG
GGCCTGGGTCGGGGTAGGGGCTTTCATATCGAAAGGAGAAACAAGTATTGGCAGCCTTGCTCCCTAGCATGCA
CGCCCCATTCCACTTCCTCCCCCTTTTCCGCCCTAGTTTTGAGGTACGGAAGCAGTAGCCTCTTCCCCCATTC
GGGAGCTGAATCACTCCGACCCCCCCACCTCCGCCCAGATCCCGAGAAAAAGAAAGCCCTAGGGTGGCAGCCA
GGGTAGTGGTCCCAGTGCGATCCAGAGAGAGGGTCCTTACCTCGATGGGGCTGACCGGCGTGGAAGGCAGGGG
CTGCAGGTACTCGGGGTGCAAAATGTGGCCAGTTCGTGCCGTCAGCATCTTCAGCACCTTGATTGGCAGGCGG
TTGGCCTGGCGCAGGGGGTCAGAGGGGGGCACGGCGTGCACAAAAGGCTTGGTGCTGCCGGCCGGGGACGAGC
CTGGGCCGGGGCCGGAGCTATTTCCAGAGAGCGCGCTGGTCCAGGCAGGGTCTGCACCGCCGCCTCCGCCTCC
GCCGCCGCCGCCGCCGCTGTGCTTACTGCTTCTTAGGGCAGAAAGCGAGGGCGCTGTGCTCATGACCCACCCG
CGCGCATGGGAGCAGCGGGGGGGAGGGCTCCGGGAGGCGCGGGGCGGGCTCGGGGCTGCGCGCTCGCCCCGGG
AGCAGGAGCAGCGGGAGGAGGAGGAGCTGGCGCGGCGGCCACGGGCGCCCAGCGCGCCTTCTCGGCGCCTGGA
GCCAGACGCGAGTAATCCTGGGTGGCCCGCAGCGGAGCCGTGGCCGGGCTAGAGGAGCCGGCTGGACTGCGGG
AGTGCCGGGCGGCTCGCGGTGTCCGCCTCGGGCTGCTCCCCTGCGCTGCGTTCTCGCGGCCCCGCGCCGGCGC
TGCGCTCTGCGATGCGAGCCGCTGCGTGTCCAGCCGGGGCTCTGGCGAGGAAACTCACTTCAAAAGCAGCTGC
ACCAAGGGGGAGATTAAAGCCTTTGCCGCCTTCCAATCAAATGGGAGCCCGAGGTGATTGGAGGGTCAAGGGG
ATGTGACGCGTCCCGCGCCGCCGCCGCCGCCGCTGCCAGGACTCTCAGTGCCGGTTTTAATGGGCAGCTCCCT
CTTCGCCGCCCCCCTGTGTGTCCCCTCCCTCGATTTCGCTGGGAGGACGAGATGGACATTTATTCTACGTTTG
CCATCCGCCGCCTCCCTCTTTTTTCCTCCTCGTCGTTCTTCCTTTCCCCAGCTCGAAAATAAACTGAAACCTT
CTTTTGAAGGGGGGTGCGCGTGAGGAACAGACTGCGGGGGGTGTCCAGAAGGAGCACCGGTGGGAGTGTGGAC
ACCGGCCGGACTGTCAACTCCAGGGGCGAAGGGAACCTGCACACCCAGTGTTTTTTCCTTCGCAGTAATCGAG
ATCCCGCGCGGCGCAGCGCAGCCACCAGGGTAAGAAGGCAAGGTGGGGAGCCGGAGCTGGAAGAAGCCCGCCC
GCCCGCTCTAATTTCCTCAGATTCCGCGGCGGAGAAACCAGAAGCTAGATGGGCAGTCGCAGCGGCGGCGGCT
CAACACCGCGAGGAGCGCTGGGCTCTCCGCCCTTCCCGGCCACGTGACGCCCGGGGACGCGTAGATTGGGGCA
GCAGCGGGGGTCACATGTTTCCTCTGTTTCACCCTCAGTCTGTCCCCCAACCCCCCATTCTTACTCTCCCACC
CTGTTTTCCTCCCTCCCCCCCTTCTTTGGGCATCTCCACCCCTCCATCAATTGTCAATGTTCCTCGACCGCAA
TCAATCAGTTATTTGTCAGCTCTTGTCAATCCTCCCGTGATTTATGTCAGCTTTTGTTGCTGATTACAAGGCG
GGTGCGACTTGAAGGGAAAAAGAGAGAGGGAGAGAGAGACGGAGAGGAAGGAGGAGATTGAGAGGGAACTGGA
GGAGGGGAAAAGAGGAGCGGCCTCCTGGGATGGGGGTGGGGTGGGGGCTCTAAGAAAAAGAATGAAAGAGGCG
CACGGTGTCAGGAAAATGAATAGCGAGAGTAAAGTGCGCAGGTGCGCCCAGGGCGCCGAGAGGGGCGCGCAGG
CCTGGAGTGTGCGCCTGCCCTCTCGGTGTCGGAGAGACGCCCTTCCACCTCTGGGAGCCTCGGTCTGTTGGGG
TCGCGGAGTTCGGGCGCGGCTCCGGGTACCCGAGACCAGCGGCGGCAACTTCTAACACGGGAGATTTCCCGCC
ACCCCACCCCGCCGCCGCGAGTCCTCGCGGGGCGTGTTGCGTGCGGAGGTCAGGCTGCCACCCTCTGTAGTTC
CCTAACCCCAAACTCGGAGACTTCTAAGAGCCACACCACCAAGGAACTTCTAGTCCTGGAGGTCAATGGTGGG
GCAAACCTCGCCTCAATTCTTTGACCCCCTCGGGTCGTAAGCAGGGCTAAGAGGCTGCGAAGAAGAGGCCTGG
CCATGGGTGTATGGGGGAAGAAACATCTCAGGCTCACTCATGCCCCCTCCCCGACCTTCTCCCACCTGCCGCC
ATCCCCGCAGGCTGGGGAGCCAGGGTAACTCGGGGCTGCTCTCTCGAATTTATTGGAACGCCGAGTCGGAATG
AGCTGCGCTAGGAGAGCCGAGGGAAGGAGCGAGAGAGGGAGGGGGCGGCTGCCTGTGGGAACGCGGGTTCTTC
CAGGGAAGCGGAGCGGGACTGCCGCGTTCCCCTCGATTTGCACCGTCACTCGGGTTGTTTGGGAAGAAAAGGG
GAGGCGCTGTGCGTGCCACCGGGTACCTGGACCTGGATGCCCAGTGTGTATGCATGCCTGTGGCGCTGCGTGA
GTTATCGGGGCTCTGATAGCGTCCGGAGCGGGTTCGAGGGTCTCCTCCAGGAACTCGCAGAAATTAGAGGGGG
TGGGGAGGAGGACACACCCCCTTCCTCGGAACGACTTAGAAGACTTTGAATCTCCCCTCCTCCGCTTTTCCGC
CCCGGCTCTTCTTTTGTTGTCAAGTCCTTTTGATAAATGGTGGGGCTGGGAGCTCTGGGAGTCGGGAGCCAGT
CTGTGCCCGCGTGGGGGGCGGGGGCCGAGCCTGGAGACCCGGTTTCGACCGGCGCGCACCTGGGGCTGAGCCG
GGTGCGCGCGGGGGTCGGGTCTGGAACTGCCCTTGGTATGCTCGCCCTCTCCTCTTGGCCCATCTCACTCCCC
TCCCCCACCTGACTCCCCTCCCCGGCTTCTTTCTCTGTCTCCCACTCCGCACGGGTACCGAGAACTTTCCGGG
GTGAGTTTTAGAATTTGCTCCTAGGCATTCTTTTTCTGCGTTTGGATTTTATCCCTTGATTCTTTGGGTTGGT
AAACTTTATGAAATGGTAACTTGACTGAAGCTCATTTGGAGAGAAGAGGGGAGTGAGGCGGTGTGTGCTTGGG
GCTGGTGTTTGTCAGTGTGAGCGTGTAAGAGCACACCTGCATTCAAGGGGGTTTGTAGTGTCCGTGCGACATC
TGAGGGAGGTGAGTCGGCGAGCGGGTGGCGAGGCCCCACGCTGAGGGAGGCGGTTGTCTGGTCTCCGGGGAGC
AAGTCCCAGGTGCGCGTTTCGGAGGGCGGGACAGTCCTACGCTGTCTCTGCGGGGCAGCGCGTCTGTGAAGCA
CTCTTATCCTTCGGGTGTGTCCATGTGTGCCTGGTTACTGAGTGCGCGGCCGTCTAGGTGTCGACCCAACCAA
TGGTAGTGCTCCTAACGCCGCGAGCCCACCTTTGGGCCGCTATCGCCGCGGCCTCCCCGCGAGGCCCGGGCAC
TGAAATTCTGGGGCCTGCGACAGGGCCGGGGGGGACGCAGCCAAGGGCGTCCCTCCCCAGCCTCCAGACTCAG
CTCTTCCCCCTCTCCTCTAATTCCAGCAGCTTATTACGCCGGCGGCTCAGGGGAGGCAGCCTCAGCACCTGAA
GCCTGGGGGGGCCGTGGAGTGGCTCCTGCGTCCCCCGGTGTGGCCACACACGCTCGTGGGGCTGCGCTGTGCT
GCGTGGGTGCGGGTCGTGGTCAGCGTGCGTTCGCTTTTCTCAAAACTCCACTCCGAGGGTCCGAGCGCATGGG
GGCGCCTGGGGGCCTGCGCGCCCGGGGCTTTTGGGAGGCGCCAGCGTCCGAGCCTGCGCACCTCGCGCAGGAG
GCCAAACCCCCGAAGGCCGGCGCGGGCCCGGGAGTGGGGGCCATTAATTACTCTGCGCCAGGCCTAAAGCCTC
CAACCCCCAGCAGCAGTTGGCGTGGATGTCCTGCGGATTTTATTTGCAAACAATGGAAATGATTTGTTTTCTC
TAAAAAAGGAGTGGGCAAGGCAGATATTGGAGGAGGGGGTGGGAGGAGGAGAAGGAAGGGGAAAGAGCTGAGG
AAAAAAGTTTGAAAATGCCTTGAACTATTCACTGTCGAGATGGCTAATCAGTATTGAGGCCGGAGGGCAGGCG
GGCCGCCTTTCACCGCCGCTTCCCTTTCATCTCGGGCTCGGCGGAGGCGCTCAATTAAAAGCCTATCAGTTTG
TAAGTAAATCAACGCCTATCAGAGTTGTCACATCAAACAAAACGATTATTATTGCAGCCCGCCTCCCCTATTA
ATCTCCCTCGAAGATAATCCGCCTGACAGGTCAGGCCCGGCGAGCTGGAAAGCCTGGCCCAGAGCACCCAAAC
AGTCCCGGACTGGCGCGCGCCCCCGGGGGCCTCCCCACCCCTGTCCTGCCCCGCCTCGCGGTCCCTGGGAGCG
GGGAGAGAAAGCGCGCGCGGAGGCCTCTGCACCCAGGTCCGCCCCACCTGACTGGGAGCAAGGCCCAGATTCG
CGGGGCCAGTAGGGGACAGTCCCGCGCGGCCCTCGCCGCTGCTCGGGGCAGGGGAGAAGCCTGGCGTGCAGGA
GCCGCGGCCCGGCCCGGGGTCTCGCCACGGCCTGCGCTCTCCTCGGCTCTCATTTATTTTCTTCCTCCCTTCT
TTTTGTTTTCTCTCCCGCGTCTTTCTGGGCTCCCCCATCTTTTTCCTTCATTTCCTTTTCCTTTTCCCTTTTT
TTTACTTGCCAGGGAGTATTTCCCATTCTGGCTCTCTCTTCTTGGTGTGCCGTATAAACCTTTCTTGCGCAGC
CACACTGCCTGGAGTAGGATGTTCTCAGGGCCCGGGTTATTTCTCCCGGGTTGCCCCAGGAGTGTGCAGTTCC
CAGAAACTCATGGCAAAGTCCTCTATAATCTCTTTCCGAGCAGGGGCTCTGAGAAGCTCTGCGCCTGTTTAAG
GGTTGGGTGGGTTTGGAGGGGTGAAGAGGAAAAAGAGGGAGAGAGACTGGTGGACAGTTGTCCTATTCTGGAA
TTAGTATTTTGCCTTGGAATTTCATAGCTGTAACGTTGCCGACCTCGCTGTTGGCGTTGCCCGGGCTTTTCAA
ATATGTAGATAAGACTCAAGGGGGCATCCAGGCCTCAGTAGTGACTATGTGTGTGTGGGTGGGTGCCTGATAC
AAGTAAATACACCCAGATAACTGCCTCTGTGGCCTCAAGTTAGTGTCCCAAGAGTTTGGGTGGGGCCTCGCTT
CTAGAAGGCGCAAAAATCGTGGCCTTCTTCCCAGTGGCCTCCGGCTTCCTGCTTTGGGATGCCTCGGAATCGA
GCCGGACCCGCCTTTTTCTGCGCTCTTCCTCCACATCTGTAGGCCCAAACGGCCACTGCCGGAGCCAGGTGGA
GCCAGGATTGAGGGGTAGCTGAAGTGTCTGTGACGAAAGGGCTGCCCGAGGGAGCCCAGGCCTGCCACCTCAT
ATGTCGGGTTCAGTGCGCCGCGAAGGCTCTCCGCGCCTGTATCTCGGAGGACCCCCAGAGCGCTGCAGTATTG
GGCGTCAGGGCCGAGCCTCTCGCAGCAGTCACGCCGCAGTCCGAGGCCACGGACATCCAATAGAGCCCACTTC
AACTTGCATGGTGCATGGGGTCCAGGACCGGTGGCCCCCACACAGGGTTTCCCAAAGCCTCTCCATTTGTCTG
CACTCTCCACTGCCGACCTTGTAGGAAATTTATTTCCATGCCCAGAAATATTGTTTGGACACAGTGGCTCGGT
TATCTTCGCGCCTGCTTTTCTTAAATACATTTATTTCACCTCTGCCACGCTGCAGATATTTAAAGATCTGTAG
ATACCGTAACCCTCAGCGATGCGGGACTCACTCTGGTTATAGATAATATTCTCTGGGTGGTTATTTGAACATA
AGTTCTATCTCCAGCCCAGATGACACCCAAGCAGGGGCTGTAAAGGACACTTGCTCTAGAATGTTTTCAACTG
AAATATATGTCCACACACGGAGAATTTAAGAGTATTTTTATATTTCTCTCTAGATCTAAATATTCAGATGTGT
TAATTACATGCCCTAGAAGCTGGAAGCGATCAGTGGTGTTCACACTGGACGTGGAGCTGTTTGTATAATTTTC
ATCTCCCTGCACTTAAACATGACTCTCAGTCTAATAAATTCAACCTTGTCATTTTTAGAATCGACGGGATTTC
TCTGGCTGTCGTTTGCGCTGCATTTATCCGAATACATCCAGCTCGCAGGCATCCTGCAAGAAACGGCTCCCGG
CTCGCGTGTACGCCGACACCTCGGCCCAACGCAGGACTCGAGGTGGTTTCTAGTGCCCGGGTGGCTGCAAGTC
TGCCCTCCGAGGGAGGCTGGACAAGCGGCGCCCCCAGGTCGAGCGGCCTCTCGCTGCCTGGCAGTGCCTGGCA
GCCCCCACCTCTGCCAGTGCTTCGGAAACCCGCCTGGCCAGGTTCGCCCGCGGTGAAAAATGAAAGCAAATTC
CCCAACAGAGGTAGCCGGAACTTTCCTCGACGAAGGCTCCCTCCTGCGCCTGTGTCTGGAGAACCCCCAGAGC
GCTGCAAGTTAGCAAGAGAGATTCGATGGCGGCTCTGGAAGGCGCACGAAGGGTGGGGCGGGGGAGCAAAGAG
GCCACTGGGTGACCCAGCCTGGTCCGGGGTGAAACGCTAGAGAAGGCGCCTCGCCTTCCTTATTTCAATGCAA
CTCCTCGGCCCCAGACGGTAAAAATAGTTTCCAAGCTGCCGCGGACGCCCAGGATGTGTTTGCAGAGATCAAA
CTGGGGAGGAGGCAGCTTTGTAAAAGTTGCAGAAAGATTAGCCGAGAAGCGTCCGCCCGGCGGGGCTCAAGAA
AGCTTGGGGACAGCTCCATGTTCCTTGGGGCGGAATGGCCCAAGAATTGGCCTGGGTAACCCCCTGCCCAGTT
CTCTGTCCTCACTTCGAGCCAGTGCTTAAATAACTTCCCGCCGCCTGCCCTGCAAACTTCCCGGCGCGGCGCC
GTTGAGGCCAGGACACAGCAAAGGCTAGCAAAACCCCGCCGCGGCGCGCTCGGCCCCGGCCCTGAGAGGCTGC
GCGGGTGGGAGGACCAGTGTGGTTTCTGCTCCCACTCGGCTGCCCAGACCCTCAAGACCGATCCCCCAACTCC
TGGGAGCGGGTGCTTCCCTCTGGGAGCCGAGATCTTGCGGGGCCAGCGAGGGCGCAAAGTGCGCGCGCTGGCC
CGCGCGGGGGCGGCCGCGCGTCTCTCCGCGGGGCCTGTCGCCAGGCCGGCCGCGGCGCGTGAGTGATGAGGGC
AGAGAAGGGCGCCCATAAATCGCGGGTGTCAGGGCGAAAAACTCTCTTTATTGTCTGCGTGATGGATGGGCCC
GGGGACGAGACACCAAATACTTCGTATCGCCTTTAAATGGGAACACATTTTCCGCGGCCATAATTCATGTTTT
TTAAATAGAAAGTTTGAAATGTTGCCTATATTTCACCAGCCCTGACATATTTATGAATCGCTCCCTGCATGCA
AATATCATTACTTAAAGCGCCGGGGAGAGCGCGGGGGAGGGGAGGAGGCGCGGTTCCCGGGGCGTGGGGGTGG
TGAACCGGGGAAATATCGGTGGAGGGGGGCCATCTCCCTAAAGGGCAGAGGGTGAGGTGCGGTGAATAGCCGT
ATCCGGAAACCGAGCGTGCCCCGGGCTTCTTTCCCGCCGCCAGACCCCGCACAGCCGCCCTGGGACGTTTTTC
GAGGCTTGGGACCTAAGACGGGTCCCCGGACCCTGCTGGGAAACCAGGGGGCGTTTTTCGTCCCTCTCTGAGG
CCATTATCCAAGCTGAAACCACCTTTTATAAGAAAAAAGTTTAAAGAAAAAAAATTTAACAAACACAAATAAT
AATAATAACCCAACATGTTTCGCGTTCTTTGCCACTGCATCGATTTTATTGATTTTCATTCTGCAAACCTGGG
AATGTGCGCGCTCGGGAGGGGAGGCTGTCAAAACCCAGTCATCGCGGGGACTGGATGGGGGACAATTCTCCGA
CGCCGCGGCCTGGACCCGCCCCCACCCAACCGGCGCACCACCTCCCAGGCACCACGGAGCCTGCGCAAGCTGC
GGGGCCGTAAAGGAACCGGCCCCCAATCTCCGGGGCTTCAGTCCCGCCCCTCTCTCCCCCCAGTGCCCTGCAG
CGCTCCCAGGGTCCGTGTCTGCCCTCCCCAAGCCCCCACTGTCAATACAATCCCTGTTAAAAAAAAAAAATCT
TTTTAGAGCCAGGCACGTGCCGTCGGCCTCTCCCCTGCCCGCCTGGCCCAGGAGGCGCCCACACCTGCGCCCT
CACTTGCCGAGACTTTTACCTGTGCAGTCCCCGGCGGCGCCTGCAGCCGCGCAGGTAACCGAGAAATGGAAGG
GAGGGCTGGGGAGTGAGAAGGACAGAGAGCACCGCCCGACACAACCAGACGCGCGGACCCGGGGCCTCCTCTC
TGGACCGGTGCTGGGGCCCTGGTAGAACCAGCTCCGGGAGCCGAAATTGAGCCATGAAGAGTGGGCCGAGGGA
GGGGCGAGGGGAACGGGCCTCAGGAGGGAGGGGCGGGCCCGGCGGCACTTCCGTTGGGGGTGGGGCTGCGGGC
TGCCGCGCCGGTCCCGCCCCTCCGCCGCGCGGGCCCGCCCGCTCCAGGCCAGGCTCCGCCCCCACCGACTCGG
AGCTGGATCTCAGGCCACGGCGCCCCCCCAGTCGCGCCCCCAACCCCGGAGGCCTCGGGCTGAACCGGGTTTC
GCAGGAGGGCACAGGGCG
CGI: 356 range = chr10: 88112905-88117344
CGTGAACGCCCTCGCCTCGCACCTGTGGCGCCTGCCGCGGGGCCCGACCGGAGGCAGTGGCTGTGGACAAGGG
CGGCCCCGGCGTAGGCCAGGATTTCCCCGCAGCCGGACCGGCCCAGCTCCGCTCCTTTCCTGGGCGAACAGCG
CCCACCTCCGGCCCAGGCGGCGGCGCCTCCGCCCGCGGCGCGGACAGCGAGAGAGAAACCGGCTCCTCCAAAC
CTGGTGGAGGAGCGCTGCAGAGAAGCGCCGGGCTGAGGCTCTGGGGGCCGCGGGGCGCGAAACGCCGCGCCTA
CCAGGTTATGCCCGGGAGAAGGAGACAGGTCGGGCTCCAGCCGCTGGGCGCTCCTCACCTCGAAGCGAGGAAA
ACACCGGGCCACTGAGATCAGGGGAGGTGCGCCCGATACAGGTACCCGGCACGCAGACACGCCCACCCCCAAA
CACCGAGAAACAAAGACTGCCCCGAGCCACGCACGCCTGCGCGGCCAGCGCTGGGCGCACACCCGCGCCCACA
CAGCCCGAAGGGCGCCACGCAACCCGCAAGAACACCAGCTCCCCGCGCTCGCAGGCTCTCCGTGCCGGCCCGC
AGCGCAGAGCAGTCCCGGCGCCGCTGCCTAGGTGGGCCGGGGAAGGCGCGCCACCGCGCATGGCACCGCGGCT
GCCGAGGAACAGAGGGTGCCCTGCGCAGCCCAGCTCGTCCCAACCCCTCCGGTGCCCACTGCTGCGACGCCTC
GCAGGCCGTGTCCCAGTGGGCCCTGGGCACAGCGGTCACTCACCTTCCTGCACAGCCTGGAATGGGTTGTTGG
CCTCGATGACCTTGATGGAGTAGGTGATCTTCTCGCTCTGCAGGATGTCATCGTTGAGGCTCAGGTCGGATAC
CGCCAACTGGAACACCCTGTCGTCCTTGGCCGCGTTCTCCTCGAAGATGGCACCTGGAGGAGAGAAGGGATCA
AGACCGGACCTGGACAAGAACCCTCTCCCCGCTTCCCTTGGCCCGAGGGTCAAGGCACTCGCAGACCGATGAT
TGCCGGGTGGTGGGAAGTCTGAACTGGGATTTCAGCTTGGCGGGGTAGATTAAGGCTCTCCGATCTCCACCTG
CACAGGAATATGTTCCCCTCCCCCCACCAGCCCTCAGCGCACACGTGCACACAGTTGACATGAGTTACACATG
CACATCCCACAGGCTGCCACCAGGTCACACACGTGTCTCACAACCAAGGCACCACATGTCCTAGCCATGCTCC
ACACAAGGGACTAAGCCAAGCTGGGGTGGCCCCAGGCAGCGCCCAAATGCCTTGACATGGTTCCATAAATCCC
ATCCCAGGAGCCAGGAAGTTCCCCGGGAGGGTGGTGTCCCCCACCCAAATCCCAGGACAGAATGATGGGTCCT
TCTCCATGCACGTCCCCTGCTGAGTGGAGCTGAGCGAAGCAGGTCTACAGTTGGCTTTCCTGCGCAGAGGGGT
CTTCCTTAGGCAGGGGCTTCGGATGGCCTGCAGCTTGGATGACTGTGACGCTGCCCGGCCTGGCGCCCTGAGC
TCAGCCTCCTACTCTCCATCCTTCCCCACTCCCATTTCCTGTACGTCTGTCGAGGGGAGTGGGGGAAGGGGAC
TTGTGTCCTAGGCGCCTCCACGTTCAGATCTAGCGGAGCTGGGGGTCCCAGAAGGAGCTGCTCTTGAAGGGCT
TTCTAGAACCGCGGACAGCTCCTCCAGGGCGCCCTCCGGCTGGCGCTTTGTGCGCCTAGCACAGCTTCCACGG
ACCCTGCGCTTCCAGCCGAGATCAGTGCGACCAGCCCGAGCCTAGTCCTGCAACCTGGACAGCTCTGGAGTCA
GCCACCCACATCCCGCCTCACCAAGCCTCGAGGGTCCCTGAGGTCCCGGAGCTAGGCCCAGTGATCCCTCGAG
CTGGGGGCTGGGTAGGAGGAGGGAGGCCCGGATTCCTCACTACACCCGGAGCCGGCGCCGCAATGCTGACCGC
GAGACCCGCACCCCTCCAGGGCGGGAAGCAGGTTTGGTCACGGGCCCCTGAGGAGGAATCGTAGCTCTCCGAG
CCCAGGCCTAGTCCTCACCACCCCACTCCACCACCCACCCTCCCGCCTTGTCCCGTCCTCCTCGCCTTCAACA
CCTCCCAACCCCCAGTTTCCCTGTGCTCGCTGGTCTTTCCCAACTTCCGGAAAGACGACTGCGGAGGGACTCC
CCCAAAGCGACCGCTGTCAGCCCCCCAACTCGGCCCAACTTCCCGAGATTCCTCCCGTGTTGCTCCCAACTCC
CACCCACTCCCCCTCGGCGCGCCCACTCCCCCTCGGCGCGCCCCCTCCTCCTCTGCGCTTTCATCTTCTCTCC
CGGTTCTCTCTCTCTATCCATCTCTTCCCGCTCAGCATCCCCCTACCCCCCGCTGCCCACGCTTCTTCCCTCG
GCTCCCACCACCCAGACCGTCTGGGCCCCCAAGACTTGGACCACGCAAAACTCTAGGACTGTCCAGGATGGGG
ATGCAGTCGCCACAACCAGATACACACGCACTCACACATACACCAAGGGCTACACAGACACACACCGGAGAAG
CAGGCAGACACTGTGTCCACTCTAACAGGCTGACAGACAGTCGTGCACGCACCAACACACGCTCAGATGGCCC
CACACACCCCAACACCCTCTCACAGTAACACCGACACCGTGCCAGGCGCACACAGCGACACACGCTGACAACA
CGCACCCACACACATTCACACACGGTTCCGGTCCGGCCTCTTTGATCTTGCCCTGCCAACTTGGCGAGCCCCC
CGCTGTACCTCCCCCTGCCCCCCGCTGCTCTGAGCTGCGCAGAAGGGCCCTCCCGACCCGCCGACGGCCCCGC
TAAGGGCGCGGGTCTCGACGCGCGTCCATCCCGGTGTTCCCCGAAGCGTCGGCCCTAAGTGTCGGTAGAGGCC
GCGGGGCCCCGCGCGGAGATCGGAGCCCCGGGGAGCGGCAAGCAGCCAGCGGGAGCGCGGCGCGGCCGGTGCA
CAGCTCCTCCGCCGGGCGGCGCGGCGCGGCCCTTCGGGGGAGCACCGCCCGCCGAGCCCCTCGGCCCAGGGAA
ACGCCAAGTTTGGACGCCGCGCACCCCCTGCCCCGTTGGGGCCCCCGCCCAGCCTCGGCCCGGCCTCCAGCCG
CGCTTACCGATGTGGATGATGGAGTCGGCCCGCACCGACACGCACTGGCATATCCAGGGGAGAAGCCACAGCG
TCAGCGCTTCCATGTCCCCCGGGCGCGCGGCTCATCCACCCGGGCCCGGGGCGAGGCCGAGGGCAGCGCGAAG
CGGGGAGGCGCTGGTCCCGGTGCAGTCCCGGGCCGCTCCCCGGGAGAGCCGAGCCCGCCCGTGCGTCTTCCCC
CGCGCGCCCGCCCCTGCGCCCTGCGCCCGCCCCAGCCCAGCCCAGCCCAGCCCAGCGCGGTCGGGCTCCCGCT
CCGGCTCCGGTGGCGGCTGCGGCGGTGCTGGCAGCTTGAGCCCAGGCCGGCGCGGCGGGGGCGGCCCGCGGCT
GTGGCAGCGGCGCTTCCCGCGGCTAGAGCGGCTTCGGGGGAGGCTGAGGCGGTGGCGGCGGCGGCCGGGCCGG
CGTGGCGGCTCTGGGCTGGCTGTGTGTCTGAGCCCCGGCGAGGAGCGAACTGCGGAGGACGCCCCCTCCCCTC
CCCCTCCCCCTCAGCTCCGCTCCCCCTCCCCTCCCTGCCCGCCTCCCTCCCCTCCGCCCGCCTCTCTACCACG
TGACTGCGGAGCCTCAGCCTCGCCGCGCGGCTCTCGCCCGCTCGCGGCTCGGAGGGGGCGCCGGGTGCTCCAC
GCTCCCGGCTCGGGGGACGCTCGGAGACCGGCACAGCGGCGGGGACCGGCCTGGGCTGCGGCGCGCCGAGCTC
TGACGGTTCGGGCCTCCTTCTCCGGTTCGCCAGGGGCGGGAGAATGGAGGAGGGCCGGCCGCTAACTGCCCTC
GAGGGGCTCCCGAAGCGCCCTGGCGACCTCAGCAGCCGCGCGTCTCGGGTCATGTCCCCGGCCGAAACAGACC
GTTCCTCGTGGAGTGGGACCTGGGGAGCAAGAAGAGAGACCGGGGCGGGGCGCCGGGCCAGGCCCCAGGACAG
CTGGGGAGCCAGAGGGGGCCGGCCGCCGCAAGCATCTCAGAGTAGAGCCCGGGCCGTGGGCTCGAACCCTGGC
TGGCCGCGCGGACCTCGGCGGGCGCCCATCCCCCGCTCCATGGGCAGCGCGCTCAGCCGGGAGTCGGGCAAGA
GGCTCGGACTCTGAAGCCCAATTCATGGCCGGAAACCAGCGCAGCCGTGACCGCGGCGCCTGGACGTGAGGAG
CCTTCCAAGCGGCCGGCGGGCTCAGACTCCGACCCTGCACGGAGCTTTCATGTGCGAGCCCGGGCGAAGAGCC
CGCTCCTCGCGGCCACAGCGGAACAGGGCTCCCTCCGCCTCCGGTGCCTGCCTCGGGCCG
CGI: 34 range = chr10: 94441310-94441717
CGAGGGTTTGATGATGCGGCCCGAGCCTGGCTGTGGTCGCCTGTCGGGGCTGGAGCGGGACCCTCAGCCGGGC
CGGGCCTGGGGGCTAACGTTTTCACAGTGCGCCCTGAGTTTCCTTGGGTTACTGCTGGGACCGCGCAGGAGGA
AGCAAAGAGTTTTTCGAGCTAGACCAACAGGAAACACATTGACGGAAATGTTGCCATAGCCCATGGGGTGGCT
TTAACTGGCCGCCCCCGCGGGCTGGGTGTGAAATCAGAGGAGGCCGCGGCTCCCCCGGCCAGGATTGGAGGCT
CCTCGCGCAACCTAATGCGGGTGTCCGGGCCCGAGCGCTTCCCGCGCAGCCAGGCCTTGTCGGTGCAGCAGCC
CCGCTCCTCCCCAACACGCACACACCCGGTGTTCGCAAGTGCG
CGI: 182 range = chr10: 99068802-99071038
CGCGCCCGACTGCGGGAGCCAGGATCAGGTCCCCAGGGCGCCCTTGCAGACAGCACCCTGAGCGAAGGAGCTC
AGAAGGCAGTCCGGCTTCACCCAGACCCCCAATCCCACAGAAGCGCCGTCCCCCAGCGGCACAGCACCCCCTC
CCCGGCGCGGTGGTAGGGCCCGACGTGACGTCACCCATTGTTTACAAATCAACCCGAGCCGGCAGGATTCCGG
CTCCCGCGGCTGCAGGCGCGCGGCTAGAGTGCCTGGCGGGCTCCGGCTTCCGCGTCCGCCCCGGCCCCGGTCC
AGACTTAGTCTTCAGCTCCGCGCCCGCTCCGCCGCGGCCCACCGCGCCCGCCGGCAGCCGAGCCCCCAGCGAC
GCCCGCACAGCTCCGGGTGCCCAGACAGGGGGCCATGCCGTGCCGGAGGGAGGAGGAAGAGGAAGCCGGCGAG
GAGGCGGAGGGGGAGGAAGAGGAGGAGGACAGCTTCCTCCTACTGCAGCAGTCAGTGGCGCTGGGCAGCTCGG
GCGAGGTGGACCGGCTGGTGGCCCAGATCGGCGAGACGCTGCAGCTGGACGCGGCGCAGCACAGCCCGGCCTC
GCCGTGCGGGCCCCCGGGGGCGCCGCTGCGGGCCCCGGGGCCCCTGGCTGCGGCGGTGCCGGCGGACAAGGCC
AGGTCCCCGGCGGTGCCGCTGCTGCTGCCGCCCGCGTTGGCGGAGACTGTGGGCCCGGCGCCCCCTGGGGTCC
TGCGCTGCGCCCTGGGGGACCGCGGCCGCGTGCGGGGCCGCGCTGCGCCCTACTGCGTGGCCGAGCTCGCCAC
AGGCCCCAGCGCGCTGTCCCCACTGCCCCCTCAGGCCGACCTTGATGGGCCTCCGGGAGCTGGCAAGCAGGGC
ATCCCGCAGCCGCTGTCGGGTCCGTGCCGGCGAGGATGGCTCCGGGGCGCCGCCGCCTCCCGCCGCCTGCAGC
AGCGACGCGGGTCCCAACCAGAAACCCGCACAGGCGACGACGACCCGCACCGGCTTCTGCAGCAGCTAGTGCT
CTCTGGAAACCTCATCAAGGAGGCCGTGCGAAGGCTTCATTCGCGACGGCTGCAGTTACGTGCAAAGCTTCCC
CAACGCCCGCTCCTGGGACCTCTGTCGGCCCCGGTGCATGAACCCCCTTCGCCTCGCAGCCCTCGCGCGGCCT
GCAGTGACCCTGGCGCCTCCGGGAGGGCGCAGCTCAGAACTGGCGACGGCGTTCTTGTGCCTGGCAGCTAACA
CGCCCGGGGTGGCCACAGCGCCAGCCTCAGACTGGAGGGCAAGGGGTTCCCTTGAGGGCTGCAGTTCTACTCA
GGCTGGTGGAGAACTCTGGCTTTTGGAAGCGAGAGTAAAAAGCTAATGACGAGGAACCGAAAAATCGCGAGTG
TTTCGCGGGTAACTGGGGTTGAGGGCCAAAATATTTGGAATGAAGGACTTTGGCCCTATTTAAGGCAGATTTT
ACAGAGCGCACCTCAAACGTACAAGTCAGTAGGACTCCTTATTTGGCGTGACCCGACCTGGCCGCGGAGCCTG
CATTTCCTCGCAGCCTCTCAGTGCCCTCCAGCCCCGCGACCATGTGGCCACAATCCACGCTTCTCCGGATCGC
GGTGCGCCGGAACCACGGAGGATGATGCCAGTTACTTGCTTTACCTTTTCAGGGCTGGCTCCTGATCCACTTT
GGGGGAGGAGAACATGAGTAGATAATTTCAGGGTGCAGCCCAATCTGCCAGACTTAAAAAAACCATCTTGTGT
CTTTGGAGGTGCTGCTTAATACCAAACATGCGGTGCCATGAAGGGACCCTTTGGGGGTTGAATAGGAGTTAAC
CCCTGCGCTCTCTTTGCAACTGTCTCTCTTCTCAGAGTGGTGGGGGAAGGCTGTACGACACGGGTGGGGAAAG
GAGGTGGGGGCGGGGAGTATTGAATGGTGGTGGAAGGGTAGAGAGGCGCGGAGTGAACCCCACGCCCTGTCTA
AAGTGTATTTTCAGAGCCGGCCCGCCTCTCCTCGGTTCAAGGTCACTGTTTCCTGGGCACGCACTGGGTTGCG
GGACAGAGTAGCCAGGTTCTGCCGGTGCTCGGAGAAGAGCGCAGTGTTTTGCAAGTGCTGGAGTCTCCTGAGG
ACACGCGCGTCGCCGCCACCGCGGGTGTGGGAAAGCGCGGACGTGCTGGGCGGCTGTGCTTCGGTAGGCGACC
ACCGCCCCTGGCCGCGCTCCGGGCTTTCACGGAAACTCCCGAGACCG
CGI: 56 range = chr10: 101277153-101277910
CGTGCACGGGCTTGGAGACGGGGCGCCAGTACCAGGCAGGGCACAATGAGGCTTGGGGCCCTTACAGTCGCTG
CAACCTGGAGGTACCGAACCGGGGACTCCGACCTGACATGCAGGCGAGGCTGCGAGGTCCAGAGCCTGGACCT
GGTTCCTAGGGAGCGCCACTCCTTCTGACCCCTGTGGCGTGCGTCCTGGCGCGCCGCACCCGCCTGGTGCCTC
GGCCCTCTCTGCTGTTCCCTGGCTGATTCTGAGCAAGGCCAGCAGCCCACGGCCCCACCCGACCCCCACATCT
CCGCAGGGTCAGGCGAGCCGAGCAGGAACTGCGCCGGGGCAGTGGTGATGGCTGGGCGTCCCTGCAGCTTCAG
GGGCCAAGGGCAATCGGGGGGCTAGGCCCGCAGACCTGGCCGTCCGCTGACGCAGCGAAGGTCTAGCGGAACC
TTGGGGATCGCTCTCCCAGTGCCGACCGAAGGCCCGGACCTCCAGGCTGGACGCGGCGAAGGCCGCATAAGAC
GTTACTTAAACATGTTACTTAAACAAGACTGCAGTAAACGTTTCTTTCCAAGTGAGAAAGGTCTTTTTCGTTC
TCAGACGGTTTGAAGGTGTTTGTGCCAACGTGACCCCCGGGGAGATTTGGAGGAAGCTTTCTACGTCCTAGGA
GGCTGAGATCCCACGGAGCCGGTTTACGGTTGAGAGCAGACAGTTTCGAGTAGATAGCGCTGGAAGAGACACG
AAGAATCTCTCTTGCTTCTTGGAACGCG
CGI: 403 range = chr10: 102974173-102980053
CGCTTTAACTAGACGGGCGGATAAATGGCCCCGTTTCTCCTCAGCCCCGACGCGCCTGCTTAGCTGCGCGCCC
CGCGGGCGCCGCAGCTCGGGTGGGCTCAGCCCTGGGGCCGCCGCCCCCAGCCCAAAGGGACCCAGCGGGGCCA
GGCCCAGGGCCGCGAAGCAGAGAGCGGCCGGAGGTGCCAGGGCCGCTTCATTGGGATTCATGAGCGTGTTGGG
CGGGCGGCCTGGGGCTTCGGGCGCGGGGCGGGGGCCGAGTGGGGGGGTGCGCACGGCGGGCGCAGATGCCCGG
GTGACCGACCCGCCGTGGTCCCTGCGCCGCCTTTGTGCCGAGGAGGCGCGCGCGGGGACCTAATCCATCAAAT
TGTCTACAAATTGTGAAGAAAATTCAAAAACCATATGGTCGCCAGCGCCGGCGCGCTCTGGGCTGCGGAGGGC
CGCGGCCGTGCCCGCACCGGGAGCCGCGGGGGGCTGGGCCCGGCTATTGTCGCCTGTCAGCGGCCGCCCAGGC
CCATTCGTCCCGGCCTTCATGGTCCGCGCTCCGAATTACAGACCCATCCATCCTAAGAGAGGGCAATTTTTGT
CGCCCGGGAGGAACCAGCCGCACGCCTGCCCCGCTGCCCTGCCGTCTCCTTCCTTCTCTGCTCCTTCTCTCTC
TTCTCCTCTCTTCCCATTCTTTTTTTCTCCCTCTGTCTCTGTCTCCCTTTCTCCGTTTCTCTGTTTCTCTCTC
TTTTTCCTCTTTTTCTCCGTCCTGTCTCTGTGGCTCTCCGCTTTCTCTCTCTGCTTTTGGAGTGTCTTTCTGT
GCTCCTATTTTTTTTTCCTGTTTCTCTCTGTCTCTTCGTTTCCTCCTGGACACGCACGTTCCTGGCTCGGGCC
CGGGGGCCCCATCGCCGCCCGAGACCAGATGCGCATTTCTCACATCAATTTTGCGGAGAAAGAGAGCCCAGCG
GCCCGGAGGCGGGACCCCACTCCGGTGACAGCGGCTACTCGCCAGCCCAGCGACAACAAAAGCCCGGAGAGAA
ACCCGCTCTGTCCAGGAAAGTGAAAGCGGCCTCAGCCCCCGCCCCAGCCGGCCTTGGGGCGCCGCAGACCCGA
GAGAGTCCTTGCAAGATCCATACCTCTGCCCCCAGCGGTGTGCCGGGGTGTGGAGGCAGAATTGGTTAATGTT
GCCAGAAATTCACACCAGCTCCCAGACGCTTGGGCTTACAGTTCCAGGTGCCCACATTGAAATTCAGCCTGGC
CTTGATGCCTTTAGCCTTTGGCCCCCGACTCCCCAAGGATGAGGCCCTCGGGGCTAGAATCGAAACTTGGGAA
CCCAAGGCTCCACCCCGCGTCTGACTGAGTGATACCTGCAGCGCTCCCGGGGCTCAGCCCTGTTTTCGGGGAG
TGCAGGGAGAATGCCCTTGGGTCTGGGGTGGGATGCAGGAAATGCAGGGCAAGACCCCCTCCCACCCTTTGTT
CAACACAAATTAATGTTGTACTGTGGTGTGCCCCCACATACACAGGCATTTTCTCCCAGCATTTCACGGCTCG
TTTTTTACCCCGACCTGGCGAAGCCCGCTTCTCTCCCGATTTAGCAGCTGCCTCAGGTTTATGGGCAAGAGGC
GCCTCCTCCTGCTGCTTCCCCCTCGCCCTTCACTCTTAAGCCTGTCCTGAAAATCCCCCCCAAATCTCCAAGG
CTAGGGCGACCGGCACGAAGAGCGGCAAGAAGCCCAGCCTGCCGCTGCTTCTCGGAAACGGGCCCACCACTCA
GACACGGTCGCCGCCGGTTCTAGTAAAATGGCAAAGACTTTATTTATTGGAGAAAGAGGCCTTGGGTACAGTC
TAGGGAGGAGAGGGGAAGGGAGGAGCAGGGAAGGGGCACTCGCAGCCCACTCACATCCAGCCACCCTCCTCTG
GCCAAGTCGGGTAGGAGTGGGGTGTTCGAAGTGGCAAGAGAGACCCAGAGCTGTGGAGGAGGTGAGGTGAGGG
CTTGGGTCGGCCTCCTCTCTGTCTCTGTCACATGCAAAAAAATTCTAAAAAGAGTACAAAATAATTATAGGGC
TTTGGGTTCTGTTTTCGATAGTTGGTTGGTTGGATTTCCCCCTGCATTGTCCCTAAGAGCCGGACTCCAACAG
TCAGTCCGAGGAAATGCGGGAGGGAGGGAGGAATCTTAAAAACAGCATTAGTGGGCATTAGGAGGCAGAAATG
GCATCGAAAACAGACTTTTCTCTCAGAGGGTGGGGAGGAAAGATCGATTTTGAAACTTGCAAGTCAGGACCTG
ACTGCCCACCTCTTCCCCTCCCACATGAGGAAAAAAGGCCCGAGGAAATAGAAGTCAACTGCAATAAGGCCGA
GGGAGGCGAGGAAGGAGCGGGCCGGTGCATTCGCCACATGCAGAGAAAAATCAAAACAGCCGGAGCTGCCACT
CCCCTAGACCGCAGGGTTAGTGTTCCCCGCCCTGGTTTCTGTCTCGCCCTCAGCAAACCCGGCAGCCCGAGAG
CTTTGAAAACATCGAAATCTCCGAGATTTAAAAAATAATAATAAAAGAAAGGAAAAATCAGGCTGCGGTGGGA
AGAACCCGCTATATAGGTTTAAATATTTATATAGAAGCCATACAGAATTGCACGGCGAGGGCTTCCGGGGCGG
CGGAGGCCGCTGGTGGCGGCCGGCCCGGCCGGCCAGCCTGGGTTTATTGCTTCGAGAGGGAAGAGGCGGCTGC
CAGGAGCCGAGTCCGGGGCCGGGGACAGGGGAGGAGGCGGGAGTTGGCAGAGGAGGTCCCAGCTCCCCTCGGC
GGTCCGGTCCGGGAGGCGTTGGGCTTTCGAGCGCTAGGAGCCCAGGGCGGCGGAAGACCCGGGGCGCCGCTCA
ATCGTCCACGTCGATCTCTTCGTCTTCCTCGTCCTCCGAGCAGTCCTGGCTGCTGGCCGGCTGGTCCGTGAGC
GGAGAGGCAGGCGAGAGCTGCAGGGCGCCAGCGCCCGGGGCCTTCGGGGCGCCTGGGGGGAGGACCGGAGAGC
CGGGCCTCGACTTGGCCCTGCCGCAGCCGCCGCCACCGCCGGCTGTGGCCTCCGAGTTCTGCTCGAGTTCGGC
CAGCGCCACGATGTCCATCTGCCCGCTGGGGCCCAGTTTCTTGGCGGACTCTACGTCGGCCTTCATCTCCTCC
AGGTCCCGCTTGAGCTTAGCGCGCCGATTCTGGAACCAGGTGATGACTTGCGCGTTGGTGAGGCCCAGCTGCT
GCGCGATTTGGTCGCGATCGGCGGGGGACAGGTACTTCTGGTATAGAAAGCGCTTTTCCAATTCATAGATCTG
GTGGTTGGTGAAGGCCGTGCGCGACTTTCGCCGCTTCTTAGGGGTCTGCCGCTGCCCAAAGATGGTCATACCG
TCGCGGCCTGGGAGGAAAGGACAGTGTAGGCTCGCGTTGGGAGAGAGGAAGCCCACCCTGGCTCTCGCCCCCG
TAACTCCGTAACCCACCCAGGCCTGTCCGGCCTGCAGTCTACCAATGTTCCCTTCTCAGATTTAATTCAGCCT
CCAGGACCAGGGCAAGTCTTGGCTATGGCAAACCATCTCCTGTCTTTGGTCTCCCAGAAGTCCCTAGGAAAAA
TTGTTTTGGTCTCTGCCCCCTACCTAAGAGTTGGTTTGAAAGACCCAAAGTCTCTAAGGGTATGAGAAAGCCA
GACAGAGACACCCTAATTGCGGTGTGAATGTTGGTTCTCCATCCCTTCCCAATCACTTCAACTCTACCCTACC
CATAAGGTCCCCGGCAAAAGACTCTCGATTCCCCACGCCGAGTAGCCGGGCTAAGAGCGCCCAGGACACTGGG
AACGCAAGGGAGCCCGGCAAAGCAAGCAGACTGCGGAAAGAGCTTGGCCACCCTTCTCCTGCCACCCCCCAGC
TCTGGCCTACCCAGAGGTCCCTGGGAAATAAGGATTGGGTCCCGTCCCACATATCTTCACTCCCATAAGCAGC
TGCTCAGGCTGGAAGGCCCTGGCGGCCGGAGAGGGCAGAGGCGAGCAGAGGCATAGGGGACGAAGCGCGCAGG
GCACAGGGCGCGAGGCGCTGGGTGCAGGGGAACCCAGCAGCTGCGCCTACCTTCGGCTGCCTGCAGAACGCTG
ACCTCCAGCCCCTTAAACGTCTTGCTGGCGAGCTCCTCCAGCGCGCACAGCGGCGAGGTCTGCGAGAGCAGCG
CGCGGCCCGCCAGGGGCAAGCCGCCCTGCGCGTGCTTGTCCGCGGCGGCCAGCAGGTGCGCCGCCCCGCACAG
CGAGTAACTTCTCCGCACAGACGGCTTGTTGAGGATGTCCTCGATGCTGAACGGCGTCAGTGGCTTGTTGGAG
TTGGCAGGCGGAGGCAGGTGGTCCAGCGGGCTGCGCCGCCGCTCCTCCCCCGGCGCCGCCTTGCCGTCCTCCT
TGGAAGTCATCTCGGCCTTGTTCGGGGTCCCGGCCGGGGCGGCTCGGGCCGCGGGGACCCAGCCCGCGGGCAG
CTCGGGCGCCGGACGGCGCGGGCAGGCAGCGGCGGGTGGAAAGGAGGCCGCACTGGGCAGGGCGCGGGCCGGG
CGCGGGGCCGATTAGCGCGGCGGCTGAGGAGGGGAGAACAGCGCGGGGCCCCGGGAAGAGGGCGCTGACGCGG
GCGCCGCTGCTGCTGGGGCTTCCAGCAATCCGGGGCCGGAGCCGGGGCGCGCTGCGCGGGGCTCCAGTTTCGC
CAACCCCGGTGCTATTTAAAGGTGTCAGGTGGCTCGGCAGTGGCTCCTGGCCCCGGGTCCTGGCGGCCGCAGT
TGGAAGAGCCGAGGCGAGGGCGCCGATCCCGGACTGCGAGGGAGGCGGAGAGACGGGGCAATTGACTATTGCT
AACAAGTTAGCCTTGATCGCGGTGTAATCAATTATCTGCAGCGGCACTTCTTTCTCTTTCTCTCTCCTTTCTC
CCTTTTTCCTCTCTTCTTTGCCTCTGTTCTCTCCTCCTGTTCTCGCTCTCCCTCCCTCCCTCTCTCTTCTCTC
TTCTCTGCTCCCCCCTTCTCTCTCCTTCTCTCCCTCTCCCTCGCCCTCTCTTTCACTCTCTGTCTGTCCAATG
CAGGCGGCTGTAAGTTGGGAAGCTCATTAATTAGCGGGCCGGGGGTAGGAGGAGCCGGCTGGAATTAGCCTGC
CTAATGCGCCTGTCAGTCCGGGCGCTGCGCTGCGTTCGGCCCGAGCTGTTTGTAAATTACATTAGCTGCTCCT
TTATTGCACCCGAACCTCGGGCGACTGAAAAGCCACCGCCCCCACCCCAAACTGCGAGCCGCGCTCCTGGCGC
ACCCGCCTCCCGCCGGCCTAGCTGCAATGACCGCACCGGCCCGAAGGTCTCGGTCTCTCCGACCCGGGATGTG
GAGCCCGAAAGAGTGGTGGGAACCCCAGCCCGGGAGGGACGCGGCCGCCGCTCGGGCCAGGTAGGACCAGGAG
CCCGGGTGGGCCCCGCTGCCACCCAGAGTGGACTTTGCGGAGCTGAGATCAAGAGCCCAGCGCCTCTACCTCT
GACCCTCTTGCCCCTCACCCCACTGCCTGGGCGACGCGCCTGGGGAGAGGGAATCTGAAGCCCTCCTGCGCTG
GCCCGCAGGAGGTCAGAGCCGGCTGCGCAGCCTTGGGTGGGCGACGCGGGAAGGGGGTGGAGGACCCCAGGGG
TTGGGGGAGGGGGCTAGTCGGAGAGCTCAGCCTTCTCCACGCGGAGAGGCGGAGGAGGGAATTGTTGGCGGCT
CTGGACGCCTCTCCCCGGCCTGATTCCGAAGCGGCCGCCCTACCTCCTCCGGCAATCTTGCTCACTTTCCTCC
GGCAGCCGCTCCCCAGGCTGGCTGGGGCCACCAACGGCCTGATGATGGGCGTCTGAAGAGTAGCCAGGCCAGG
TGCCGGGGCTAACGGGGCCGGCTCCGTGCCTCCCTGCTGCG
CGI: 295 range = chr10: 106389558-106392802
CGGTCACGAAGGATCTCAGCTGCACCAAGCGCGCAGGCTACACTCCTGCAGTAGCGGATTGGGGACCAGATAA
GCCCACGCGGCTCCCGCCTGAGTACCCTCTTAACTGGCGGCCGACACTTTGAAACAATTGAGTCCGTTCAGAA
ACGGACTGGGGAGAGTGAGGGCACGACCTCAAAATCCTAGGCAGCAAAATGAGGTCTGGATCCTCCCTGGAAG
AACAGACATCTCGACTACTCTCTCGCCCCACCTCTGGCCGGGAGGTCGGGGCAAGGAGAATCCCTCAACCGAG
AAGATCTGGCAAGTCCCCGATCCCACCGGGGCCTTCCGCCTCTTTTCCCTCATCCCCTAGGAGGCTTTATCAG
GTTCTAACCGCTTGTAGTGGGGGCCGTGGGTGCTCGGGGCGCCAAGAGGAGGGGGCTGCCGAGAGCGGCCTGC
CTAGTTCTCAGCATTGCCTCTTTGACCACTCGCAGGCTCCTGGAAATGCAAACACAGCCCGTGCGTGATCCGC
ACGCGACCAAAAGCCGAGCGCACACCTCCCGCCCCCGCCCCACTTGCCATCGCTCACACTAACGTGCACACAT
GCTCGTGCAAACGCGCACGCACGGAACCGCGCGCCCCCTCACACCCAGCCGCGCTCCCGGCCCGGCTCAGCCA
GGTGCCCCCACGCGGCAGCGCCCGGTCTGCCCGCCGGCCCCCTGCGAACCCCTCGCCTCACGCCCGCCTGCCT
GCGCGCACGCACGCGCACGCACGCATTCCCCACGCCCCCGCGCGGGGGCGCAGGCCTTGGGTGGCGGGGTTTG
GCCGGGAGCCGGCCGGGCCAGGGAGCGGCGAGCAGAGTCCAGGGTGCATCCCGCGCTTGGCTTCCGTGCGCAG
CCTCCCCGCGCGGAGGCACCTGGCTCCCTCTCGGCTCTAGAACGCGAACAGTTGGCGTTGAGCACACAACTCC
TCCTCCTTCTCCCCCGAGACCCCTGTACCCTCCCCGCGCGCCATCTCCCGCCCCTCATAACAGGCCCGAAGAG
TAAACCCCCAAACGCGTCCAGAAGCGGCTCCCAACTCTTCGCCGGGAGCACGTTGGAGGCTGGATTTCGGAGA
GACTCGGGATTGGGGTCTATTGCCGGCCCCTCCTGGATCCGGCTTGATTTTCATATTTTAAGAAGATTTTCTT
ATTACCTTTGATTACTCCTTTTTACCAAATTTCTGGAGGAGCTCAGTGGGGAGGATTGGGGGGAATCTGATTT
TAAGAAAGAAAGCACCGAAGGGGCAATTATTAATTTTCCTCGGGTTTGGAATCACCCTCTGGACAAGAGAACG
GGCGAGCGGGAGCTAGGAGGGAAGAGTGGAGAGGACCGGCGAGGCGCGCCAGCCGGAGCCACCTCCTTCCCGG
CCGCCCCCTCCCCACTCCCCCTACACACACACGCTCGCTCGCTCGCCGGCGCGCGCACACCCCCCGCGCCGGA
CCCGCACCTCGGCGGGCGCCACACACTCGGCAGCCCGAGCCGCGGTAGCCGCAGCGGGATGGAGGCGGCGCGC
ACGGAGCGCCCCGCAGGCAGGCCGGGGGCGCCGCTTGTCCGGACGGGGCTCCTACTCTTGTCGACGTGGGTCC
TGGCCGGCGCCGAGATCACTTGGGACGCGACAGGCGGTCCCGGACGCCCGGCGGCCCCGGCTTCGCGGCCACC
GGCGTTGTCTCCACTCTCGCCGCGGGCAGTGGCCAGCCAGTGGCCGGAGGAGCTGGCGTCGGCGCGGAGAGCC
GCCGTGCTGGGGCGCCGGGCCGGACCAGAGCTGCTGCCCCAGCAGGGCGGCGGCAGAGGCGGTGAGATGCAGG
TGGAAGCCGGAGGGACATCACCGGCAGGCGAGCGGCGGGGCCGGGGCATCCCAGCTCCTGCCAAGCTTGGCGG
CGCGAGGAGGAGTCGCCGGGCGCAGCCCCCAATCACCCAGGAACGCGGGGACGCCTGGGCCACTGCTCCGGCC
GATGGTTCCAGAGGAAGCCGTCCCCTTGCTAAGGGTTCCCGGGAGGAGGTGAAGGCGCCGCGGGCTGGGGGGT
CGGCGGCTGAAGACCTCCGGCTGCCCAGCACCTCCTTCGCGCTGACCGGGGACTCGGCCCACAACCAAGCCAT
GGTGCACTGGTCGGGACACAACAGCAGCGTGAGTACCCACCCGGCGGCGGGTCCGCCTGTTTCCTGACACCGA
AGGGGAATGGGGGGGTGGGTGGGAGCGAGGGACAGATAGTTGCTCGGGGGTCGAGGCGGGGGACGCCTCGACT
TTTCGAGATAACAGGTTTGTCCGATTCCCCCCACGCCCCCAACAGGTTAACGGAGTTTGTTGTTAGACGCTGT
GTGTGTTTGTTTACTGGAGACCCTAGGCTTCGGCCGCCGGGAGGGGAGTGGAGGAAGGGGCTTCTTAAAGATG
AGTGGGGGAGGGATCTGTGCTCACTTTCTCCAATACTTGGCTTGGAGGGTCAGTTTTCCTGTTTGCGGGGTGC
TTGAATTCTTGGATGAGAAAAAGGGCTGACTTGGGGCGGGAGCCGCTGAACAGACCGATTCCTGCGGCTGCCG
GGCTCCCCCTACCCCCACCCCACCCCCACCCCCCCTCCCGTCACGCGAAAGGGAACCCGGAAGGCCATTCGGA
CTCCCAGCCTCCTGCTCGCCTCGGGGTCGCTGCTATCCGCTCCAGGCGCGCAGTCCTCCAGCCCAAGAGGGAG
GCTCGGCCAAGTCGGCCCCCAGCCTTGGCCTTCAGGTAACCCCGGTTCCTCCTTCAAAGTCCAGGGAGCGGCC
CTGGAAAGCCGTAGCAGAGGCCGTAAAAAAAAGTTTAAAGCGTGAAGCGAAATTCCACACCCATCCAGCGCTC
ATGCCACACCGCTCGCCCTCACGCACGCACAGGCACACGGAAGTCGCTCAGCAGAAAACTCTCGACTTCACCA
TTGCGTCCTGCGCCACAAACGGCTCCCTGAGCGGAGTTGGGTGCCTGAGCTTCCTGCACACCTCTCCACCCGC
TTTTCCCCGCCACCGGGTTCTCCTGGACAAGGATGTACCGAGAGGTGGCGTCGTTGAGCCCGGTCTGGCCTAC
TCCGGCATTCCGAACTGGGCGCCCGACTGAGCATCGCGCCTGCCTGGCAGCTGCAGCGGCCCGCAGCGCGTGC
CCGGAGGGGCTCCCCCTACCTCGCCGGCACCCAGCGCTGTGCAGCCAAGCAAAGAAAAGGCGGGGGACAGGTT
CCCACCATCTCCCCGACTTCCCTCCCTCCCGCG
CGI: 56 range = chr10: 124891898-124892607
CGGGCGCTCATTCTGAGCCGCGACGCCCCCTCAACAGGCTCCCGGCACCGCAGAGCCAGAGGCCACGCGGTGA
GAACCCCAGTGCGTGCGCTCTTCTTGTGTGAGAGGCCGGAGGTAGAGTTGGGAGAAAGAGGAGCCGGCGAAAA
GGTTAGTGGGATCTGCTTTCCCTTCTGCGGCCTTCTGGGCCAGCTAGGGCCTGGGAGATGGGGACCAGGGTCG
GAGGCTTGGGGGCGGGAGGGCGGTGCTGCCGGCTGCTTCCTGCAAGCGGTTTGAAGAGGCATCGCGTTGTCCG
GCCGCCTGCGCAAGGGCCACGCGCTGCTGCTTTCACCCCCTTGCGCCCGCGGGGCACCTGGACTCCCCTTAAG
AGTCCCCGTGGGGCCTGAGCTTCTGCTGGGCGCTACGCTGCCCTCCACGATTCCATTTTGCCCCATTTACTCG
GGTCGTCCACTTCCCGCGGCTCAGTGACCCAGCCAGGGGGCGTCTTCCGCTAGCGGTCCAAATGTAGACTCCG
CAAAGAGGCTAAGAAGACCTGTCTACCCGGGTGCGCGCGATGGGGTCAGGGTGTAAGAACCAGGAGCCTCATA
GAAACCTCTGCTTGGGGTCCAAAGCCCAGCCGGGCACTCCCAGAGGACAACATCCGCCCCCGCATGTACACGT
GGCCCCGCAGGACCCAGCCGCAGGGCTCCCACGCTCGGCTCCCCGCCCTCTCG
CGI: 32 range = chr10: 128863581-128864054
CGACCACTTCCGTATGAGGCACGATTCGTTGGCATTCTTCACCTGCAGCAACCGCTGTGGGACTAGGCTGGTT
CCCCAGCCCCGGCGGGGTGTGAGTCTGCGACGGCTGCTCACTACATTCGGGGGACAGGCACTGCATCGGGGGT
GAGCAGGCCAGGGCAGTTTCCGAGGGCGCCTGGAGCCCGTTGAGATGTGTGGCTCTCCTCCGCTCGTCATCTG
CCGGGCAGAGTGACCACTGGCTGGCGGCTGCAGAGTCTGACAAACCAGGCTCGGGGGCCCTGGCACTGAGGGC
AGGTGCGTAAACGGTGGCAACCTCCGTTTTAAACACCCTCCTGAGGGCAGGTGGAGCGGGCTCCTCGGAGTTT
GGCCTCCCCCGGTCCTGCTTGGCCCTCCCGAGCAGCTGGTAATCGGGCTCTTCGGATGGAGGCCGAGTGGAGT
TTTGGAGCGCAGCTTCTCCATAGCTGAGCGGCTCCG
CGI: 38 range = chr11: 22319439-22319953
CGCCGCCGCCGCGGCCAAGGGCACCTGCAGAATGTGAGAGAGCCTGGGAGGTCTTGCAGCTTGGTGTCACCCC
ACCACCCTAATCCCCGAGGGTGGGGGGAGGTCGACGGCCCTCCTCCCAACCCCGACGGGTCCTGAAAAATGGG
AATGGGTCAGCATCGGGGGTACCTAAGCCGCCAAGTCCTTGACTCGCCCCTGCTCTGCCGCGCAGGGTGCTGG
AGAAGAAGCAAGACACCGGGGAGACAATCGAGCTGACGGAGGATGGGAAGCCCCTAGAGGTGCCCGAGAGGAA
GGCGCCGCTGTGCGACTGCACGTGCTTCGGCCTGCCCCGCCGCTACATTATCGCCATCATGAGCGGCCTGGGC
TTCTGCATCTCCTTCGGTATCCGCTGCAACCTGGGCGTGGCCATTGTGGACATGGTCAACAACAGCACCATCC
ACCGCGGGGGCAAGGTCATCAAGGAGGTGGGCAACGTCTGGCCGCCCTGGCTCCTGCCCTTCGGCCATGCGGC
CTCG
CGI: 98 range = chr11: 31776637-31777992
CGGGAACGTGAAGCGAAGCTCACCACCGGTGCCCGCTACCCCCACGCCGGCAACTCTGTGCTTCGTTTGGCCC
ACGTGTCCTCCCCACGCAACTAGGGGCGACGGTCCTGTGCCTGAGGTGACAATCACCCCCCAAAAACCTCACT
TGCGGGTGGGGGGGTGGTGATTGCCAGTTGACCCAGAATTTTCTAGCAACTAGGCGCGTTAAAGTGAAAAGCC
CCTGGACTAGCTCCACCTCCGGCCCCAACCATCACAGGCGGACCCTAGCTGATTTGACTCTCACTTCCCGCCC
TCAGACTGCCGGCGACGAAAATCCGCCCGAATCGGGCGCCACCTCTGGTGGAAGCTGCTGTCCTCGGCTTCTG
CCCAACTCCAAGAAGCGGAAGGGGGGTGTATCCTGCGCCCCAAGCTCATGGGAGCCCACGCACCGGGGAGAGC
CCGGAGTGGAGGCTCTGGGCTCAGCCCTCCCAGGCCTAGGCCACCGTGCCCTGAGTCCCTCCCCAAGACTTCT
CGGACTAAGTGGGCCAGACTCTTGTCAGGGGAGGGATCACCAGGACCTCAGATTGCTGGGGGCGGAGGGGTGG
ACGCTCGTGAGTGCGAAGTTCGGGTGTCACTTGGGTGTGTCCAGTGTCTACAAGTGGGAATCCTACGGTTTCA
AAAGTCAGGCAGGGATGGGGTTGCCTACACTCGGTGGGGTCAATCGCTAGTCTCACCAGAGGCGGGAGCGGGC
CTGGGGGCCCTCTGAGCTCGCGGAGGCGGCGGGTTCGGGGCCCGTGCGGGCGGGGTCGCCCAGGGGAGCCCGG
GCCCCGCGCGTCAGGAGGCCTCCGCCGGCCGAGCGGCCGCGCTGGGAAACAAGAAGCGAGCGCTTTGCTCCCT
ATCTTCCCAGTGTCCGTCCTATATTGTTTTCTGCTCTTAAAACTGACATGTCTAATTGGCAATTGGTGCCGAA
TCGTGTCCAGAGGTCTCTTGTGGAACATTTCTACAGCTGTCTCCTTCAACTAGACGCTTATTCATGTCGCCTT
AATGAGAAACAAAACGTTCTCTAATGAGCAATTACAGAGCGACAGGATTGTTCCCATAACAAATTCTTGCGAG
TGACAGAAGCATCCTTTGTACCAGATATTTCGCATACTGTTACCGATTTTCCCTTCCCTCGCCCGACTCCATG
GAGGCGCCGGGCATCCGGAGCCGGTCCGAGAGCTCACGGATGCGCCGGCAGCCTCCTCGCAGTCCCGCGCGCC
GCCCCTGGCCCCGAGCCCCTCGGCTCCGTTGTGCTCCTGGGAGTGAGACGCCACGTCCCATTATCCCGCATAT
TATCTCCTTGTCACGAGGACAACAAATACCGATTAATCTTCG
CGI: 61 range = chr11: 68274244-68274755
CGGACGCCCGGGTGGGAGGCTCCTTCCAGGACCCAGGCGCCCAGGGGCAACACCGCCGGGCTGCGGTGCGCGG
GTAGCAGCGAGGACAGGAAGTGCACGTTGCAGGCGGGCGGCTGCGGGGCCTGCAGGAGCGCGACGTCCTCCAG
CGCGCTGAGCTCTGGGATCCCGGGGTACTCCCCGAGGAGCTCCCCGCCGTCGCTGTCGCCCCCCGCGAGCTTC
GCCTTGACCTGGCCCTTGCAGTCGGCGCCCAGCGCGGGGTTGAACGCGTGCAGGACGGGTTCCTTGGGGTCCG
CCGGGCCCAGGTACGCTTCTTTGAAGACGTGGAACTCGTCCTCCTCGTACTTCACGGGGGCCTTCAGGCCGAT
GTTCTCCGAAGCGAACGGACCCTCGGGGCTTAAGAGCTCCGTCACCATCGCATCCTCGGGGCTGGGCAGCCCG
CCCGGCAGAGGGCCCTCCTCCATGGCGCAGGGCGGCGGGGCGGGATGGCGGGGGCCGCGCACCTGCAACACGC
G
CGI: 269 range = chr11: 117983446-117987106
CGGACGGGACGGGGGACGGGGGCGGGGACTGGCGGGAGGGGGGCGGGACAGGCTCGCTCTCCTCCTACTTAGC
GAGCTCCCGGGGAAAAGCAACGGTGTCCTCCTAAGCCTGAGGCCACCGCGACCGAGCCGAGCCAGGCTAAGGG
ACCAGTGTCTCCCTGCCCCCCCCCCACCTCTAGGTAAGAGCGCCCCGTCCCACTACACTTGCGGGTCCCATTC
GCTGCGGTGCTAGGACTGGATAAGGGGAAGTCCCCGGGGCCTGGCGAGAGCCCTGAGATCAGCTCTAGGCTAG
GGAGCTCGGCAGAAACCCGTGGGGGAGAGAGGGCACCCCAGGTGAGTGCGTGGGGGCGAAAGGAGCGTTATGG
GGAGTTTTCCTGTGAGCCTCTTGCTTTTGCCTTCCTCGGCCGCTGCCAACGCCACCGCCAGAGGGGGCCGTGA
CGCTCTCCCCCCCTTGGAGAAACTCTGATCCTGGCCCTATCCAGACTCTCCCGCCGGCACCCAGGCGGCCGGG
CGGACACTCGCGGGGTATCGGGCGGCGAGCGCGCGCGCGGGTTTTCGTCCTCCAGCGCCCCACACCTCCCCCT
CTCCGCCCACAGCAGGACCTTGGGGCGGGGGTATCTCCTGTGACGTCTCCCCGCCTGTCCCCAGGCCGGCCGC
CTTGATGGACCAGGAAGGGATTCGGAGTCCGGCTCAGAGTCTTGAGCGTCTAGGAGGGCTGCCTGGGGGTGTC
CAGGAGATGGGAAGCCCGCCTGGGGCCTCCCAGGCACTCCCCAAGGCCCCACGTCCTCGGGGGCCGGGGAGGC
CGCCTGGGGCGCCTTGCCACGCCCGCGCGGTCCCTATTGGAATCCCTAGCGGAGTTCCCCGAGCGGAGGCTGA
CCCAAGTCATCCGGGCTCCCCCGGGATAGGGAAGTGCGGGCGGGCGGCTGGGTAGGGGCGCCGGCGCAGGGTG
GCCGAGTCGCCCGCTAGCGCTTCCGCCGAGGCAGGCTCGAGTGGGGACTTGGCCGGGCGACCGCACAGCCCTG
CCGGGGACCCACGGCTCTGGGGCGGGGCTGCATTCTGGGCCGTTAGCTCAGCGGTCCTGGAGCCTCCCGAGGC
TGACTCATCGGGCGGCGGGCTCACCCCCCAGCCGTCAAACGCAAACGCAGGCGCCCCACCACGCCGGGCTCCC
ACGCGGCACACACGCACGCCTCCGCGACACTTCGCACACCTACGTCCCTGCGTCACGCCACCCAGACACACCC
GGACCCGCCCACACGCCGAGGCCTTCCCACGCACTCCATGCCTTACGCCTCACAGGAAAGCGCCCCGCGCTCA
CGCAGCCCCTCACACCCGCAGCCCCGCTTACACGCGCCCCAGCTCACACATGCACCCCAGTCACACAGCCTAC
CTCACACACGCACCCCAGTCACACACACAACCCAGCTCACACACGTACCCGTCACACATGAGGCCCCAGCTCA
CACACGAAGCCCAGCTCACACACGCAGTCCCAGCTCTCACACACACACCCCAGTCAAACACGAGGCCCCAGCT
CACACACGAAGCCCAGCTCACACACACTGCCCCAGTTACACAGCCCAGCTCATGCAAGCAGCCCGTCACACAC
ACAGCCCAGCTCACACACACAGCCCAGCTCACACAAGCAGCCCGTCACACACACAGCCCAGCTCACACACACA
GCCCCAGTTATACACACACAGCCCAGCTCACACACGCAGCCCGTCACACACACAGCTCAGCTCAATACACAGC
CCAGCTCACACACACAGCCCCAGTTACACACACAGCCCAGCTTACACACACAGCCCAGCTCACACACACAGCC
CATCACACACACAGCCTATCACACACACAGCTCAGCTCAATACACAGCCCAGCTGACACACGCAGCCCAGCTC
ACACATACACTCCAGCTCACACACGCAGCCCGTCACACAGCCCCAGCCACACACACAGCCCAGCTCACACACG
CAGCCCAGCTCACACATGCAGCCCCCTCACACATGCAGCCCCAGTCACACACACAGCCCAGCTCACACCGCAG
CCCCAGCTCACACACGCGGCCCCTCACACACATTCAGCCGCCCTTCCCGCAGCTGCCAGGCTCGGAACGGGCG
GTGTCTGTGGGGGCCGCCCCGTTTCCCGGCCGCGCAAACAAGCGGCTCCTTCTCTCTGCCCCGCCAAAGAAAG
GCCGCTTGTCAGGGGCGGGCGGGCAGGCGGCAGCGGCAGGCGCCCAACACTGCGGCCTTGTCCCACGCGGGCA
GCCTGGGCAGGAGCAGGCCGAGGGGTGCAAGGGGCCGCTACCTTGCGGAAACCTCCCTCCCTCGGCCCTGCGG
ACCGCGGAGAGGCACCTTTCCACCACCGGACACCCAAGCAACAGCCCTCGCTCCATCCGCGCTCTCCCGGCTC
CCCCTCTCCTCGGGCCGCCCATCTCTCCTCTCTTCCGCCTTTGGGGTCCCGGTGGGCCCCAGCCTCCCTCTCC
TTCGCCCCATCTCCCCGCCCGTCAGCCTCCCCTCCGCTGCCCTCGCGCATCCCCAGTGTTCCCGTCTGTCGTC
GCCTCCACTTGAGGACCCGCCTGTCCTTTCTTCCCCCGACCCCTCCACCTCTGTGTTCTTCAGTCTCCCCGCA
TCCTCTGCCCTCGGTCTTCCCCTCCCCAGCTTGCATTTTTTCCCATCTCTTAGTCTGCCTTTCATTTTCCCCT
TCACATCCCGGTGGCTCCCCTTCCCCGCCCCGTCCCTCTGCACACCCCCATTCATCTCTGTCAGGTTTTTCTC
ATCCTTAAGTTCTCTCGTCCCCCTCCCCACTCGGGCGTCCCCCGCTGGGCTCCCCGCCTCAGTTTCCTTCCCT
TCCTGACTCCTTCCTCTGACGGCGGCCCTTTCTCGAGGGCGGATGTGCGCCTGGAGGGCGAAGGCGGCGGCCG
AGAGGACCCCAGCTCGGCCTGGCGGGCCTCTGGCCACAGCCATGCACCGCTTGGGCCGAGGCCGAGGCCGACC
CCCAGGGACACAGGTGAGGCCGGGCGACCCGCGGGGCTCCGGGGAGCGCCCGAGCAGTGGCCCCGCGAAGGGC
CGGGTCTGGTGCTCTGGGGCTGGCTTTGGACCTCTCGTCCTGGGACTCCGTGGGAGCCCGGGAGCTGTGTCAG
TGCCCGTTGGTGCTGGAGCCAGTCGGCCCTTCCTTGGCCTCCTTCAGGCGGGGGCCAAGACCCCCGAGAGTTC
ACTCTGGGTGCTCCACTCGGCGGAGAGGGCTTCAGACTGGTGTCCCGCGTGGCTGGGGTGTCGGCGCATTCCC
GCGGGGGAGGAGGCCGAGGGCCCGGGCCGGGGTCACCTGCCGGCGCCCCGGCCTTGCGCACAGAGGGCCTTGC
CTGTCGCTCGTCAAATCCAGACACCTGGGCCTCCGCCACTCGGCTGCCGGGGCGGCACTGGGGCGTCTGTACC
CAGCGTGCGGGAGGGCACCCAGGGCCGGACGCGCACCGCAGGGGTCTTTTTTTGGCCGCGGGGCCGGGCGGGC
GGGTAATGACAGCCGGGTTGCTGGGGAGCCGCGGGCCAGATGGAAGCGGGGCCGCAGGTGAGGGACGTCCCTC
GCGTAGCGCCACTCAGCCGCCGGGGCCAGAGCGGGAGTCAAGGTGAGGGCGCCCCCAGGTGGCCGCTCTCGGC
CGCGGCGATCG
CGI: 97 range = chr12: 1844001-1845219
CGTGCGGGTGACTCCTCTTCCTGCCGACAAGGTGGGCGATGAGAACGAGGAGGCCCAGTCCCACCAGGGCGCC
GCCGACGGCGATGGGGATCGGCGTGTTGTTCTCGCCCAGCAGACGCTCCTCCGCAGATCCGAACTGGTTGCCT
TCCACCTTGAAAGCCTGGCCCCACACTGGGAATATGTTGATTGAAAACGCCTTCGTGCCGCGGACACGCTCCG
CTCCGGCTGTAGAATTGCCGATGGCTGCCCGCAATGCTCGCAGGGAGTCGTTGGCAGCTTTAAAAGTGGGGTC
TCTGGGGTCAGGAAGAGTCGTATTCAGCTGGATTCCTCGTAGGAAAATCCGGCTAGAACCTGCATTCATCCCC
AACCGGAAGCCCAGGACCGTGGTGCCCTCGCCGCGCCGCTCCCGGGTCTCCAGGTGGGCGCCGCGCTCCCGCT
GGCTGAGGTCATGCCCAGGTCACCGTCGCGTGGTCCCTCCTCTCTGGGTGAGGTTCAGCTGCAGTCCCGCGCT
GGCCGGCAGGCAGGCCCCGTGGGTGCCGCTCACGCTGTACCTGGCCACGGAGGGGAGAAGGGGCTCTCGGCGC
CGTGGCGGGGAAGGCGCGTCTTGCTCGTGGCGCGTCTCTCCCTTGCTGAAGCTGCTGTTGGAAATCTAGGCCT
GGATCGGGGCACCGCGGAGCCTGATGGTCTCGCTGTTCGTGCGGACCTGGGGGCCTTGATATCTGGTAGAGAT
TCCACAGTCCTGATTTCCTTGGAGCTTGCACTGAGGAAAATGTGTGTGTCTGACAAGTTGTAAACAAAACTCA
TGAGCTGGACGCTGTCACGTGTCGCACTTCTTGTGAAATGGAAGGTCAGTGTCTGTCTTCCTCCAAAGCACAA
TCGCGTGCCTGGGGTCGGAAGTGTTCTCTTTACTGCAAGAGCCACTGTCAAGCACTTCCGCATTGGATGGCAG
GTCAAAGGTCACATTCTTAGAGCCACTCTTAGAGTCGTAGTTCATCGAGAAGGCAGCGAAGCTGGCCATTACG
CAGGCTGTCCCGTTGCCCTTTTTCACCGCATCCGCTGCGGCTGCACCACGCACGAGGCCCAGCAGCAGCAGCA
GCACCAGGGGCAGCCGGGGGCTCCACCAGATGCAGCCCGGGCGGCAGGCGCGAGGGGAGCCGGTGTGTGGGGA
ACCGGGGCGCGGGGAGGCGGTTGCGGGGCGCTGGCCTGAAGGACGGTGGCG
CGI: 16 range = chr12: 40253533-40253742
CGACGGGACACGGTACATCACAAAGAGACCCGTGCGAGACCGAATCCTGAAGGAACGTGCCTTAAAGATCAAG
GAAGAGCGGAGTGGCATGACCACAGACGATGACACCATGAGCGAGATGAAAATGGGGCGCTACTGGAGCAAAG
AGGAGAGAAAGCAGCACCTGGTTAGGGCCAAAGAGCAGCGCCGTCGCCGTGAGTTCATGATGCG
CGI: 79 range = chr12: 52726910-52727810
CGTGTTCCCGGGCGGAGGTGCGCGCAGCCACCCCAGGCTGCTGCCAGGTGCCCGCTGGGGCTGCCAGGGCGAG
GAGGCCTCTGGGCTGTGGAGCGAAAGTCAGATCCACCGCCTACTGCGGGGTAGGGGCCGCAGTGGGGACCGCC
AGCCCTGTGGTCCCTCTCGCGCTGACTGGCGTAAAGTTGTGGCCGAATTCGCATCTCTTCTGGTGCTTCTCGC
CCGCCAGCGCAGGGCCCAGGTGTTTGAGGCGAAGGGGCTCTAGCTCCCCGCAAGCCTGGAGCCAGGCGTCGCG
CTTCCTCCGGGCTTAATCCAGACCTTTCAACACACACCTCATTCGGGGGAGGAGAAAAGCACAGGACCGCGGA
GAGCCCAGCTTTGAGGCCAGGCCTGAAGGGATAACCCACACAGGGAACGTTTTCCTATCAGAGAATAATGGAG
CACAAAATAATTCAGAAAGCGAATGGGCAGGACCACAGCCTGAGAGTCCCGCGCCGCGGGGCCGCTGCAGAGC
CGGTCTCCCGAGCACCGCGGCAGGACCATTTCGTTGGAATGTAGGGCGAGGCCGAAGCCCGCCCCGGACCCAG
GCCGCGAGGTGCGCGCCGGCCGCCGAGGGGCCGCCTGTAAATTACAGCCCGCCGGGAGGACTCGGAAATACAC
AAAAGGAGCCGAAAGATTTAAACAGTCGGAGGCAGAGGCGTCCCGAGGCGGCCAAAGCGGAAATCAATCACGT
AATTAAAACAGGGAGGGGACGAAGCCCAAGGCTGGGGGTCCCGGGTTCGGAGGAGGCGGCCAAGGTGCAGGCC
GAGGCTGGCGAGCGGCTTAGGGACGTGGCTCGCCCGCCAGGACCAGAGCGCGCGGAGGGGCTTCGGGGAAGTT
TATAACACATCGCTATTGATTCCCG
CGI: 32 range = chr12: 79634857-79635257
CGGAGCGACAGACTAGGGAGCTCCGCCCGGGATTTGCCCATCGGCGGAGGCGCCAGGCTCCCGTTTCTCCCCA
TCCCTCTCGCTGCCGTCCAGGTGCACCGCCTGCCTCTCAGCAGGATGGACGTGATGGATGGCTGCCAGTTCTC
ACCTTCTGAGTACTTCTACGACGGCTCCTGCATACCGTCCCCCGAGGGTGAATTTGGGGACGAGTTTGTGCCG
CGAGTGGCTGCCTTCGGAGCGCACAAAGCAGAGCTGCAGGGCTCAGATGAGGACGAGCACGTGCGAGCGCCTA
CCGGCCACCACCAGGCTGGTCACTGCCTCATGTGGGCCTGCAAAGCCTGCAAGAGGAAGTCCACCACCATGGA
TCGGCGGAAGGCAGCCACTATGCGCGAGCGGAGGCG
CGI: 30 range = chr12: 95164929-95165298
CGCGGTGGAGATCAGCCGGGAGAGCCTTCTGCTGCAGGACAGCGACTGCAAGGCGTCTCCGGAGGGCCGCGAG
GCCCACAAACACGGCCTGGCCGCCCTCAGAAGCACGAGCCGCAACGAATACATCCACTCAGGCCTGTACTCGT
CCTTCACCATTAATTCCCTGCAGAACCCACCAGACGCCTTCAAGGCCATCAAGACGGAGAAGCTGGAGGAGCC
GCCCGAAGACAGCCCCCCCGTGGAAGAAGTCAGGACTGTGATCAGGTTTGTGACCAATAAAACCGACAAGCAC
GTCACCAGGCCGGTGGTGTCCCTGCCTTCCACGTCAGAGGCTGCGGCGGCGTCCGCCTTCCTGGCCTCGTCCG
TCTCG
CGI: 35 range = chr12: 113609113-113609535
CGCGCGAAGCAGAGAACGAGAGGAAAGTTTGCGGGGTTCGAATCGAAAATGTCGACATCTTGCTAATGGTCTG
CAAACTTCCGCCAATTATGACTGACCTCCCAGACTCGGCCCCAGGAGGCTCGTATTAGGCAGGGAGGCCGCCG
TAATTCTGGGATCAAAAGCGGGAAGGTGCGAACTCCTCTTTGTCTCTGCGTGCCCGGCGCGCCCCCCTCCCGG
TGGGTGATAAACCCACTCTGGCGCCGGCCATGCGCTGGGTGATTAATTTGCGAACAAACAAAAGCGGCCTGGT
GGCCACTGCATTCGGGTTAAACATTGGCCAGCGTGTTCCGAAGGCTTGTGCTGGGCCTGGCCTCCAGGAGAAC
CCACGAGGCCAGCGCTCCCCGGACCCCGGCATTAGGCGCCAGCTGCCGGCTATCTGCG
CGI: 121 range = chr13: 35817738-35819004
CGCAATAATGCTGCGTCACGAAACTGCGCATTCCAAGAGAAACTTTTCTCAGGCCCAGAATTAAGTCGGAGGG
ATCCGCCGCGCAGCTCAATCCCTAGGAAGCATGAAAGAATGTATTGTAAAGAGTAAAATCACGCGCAATCCAT
CCCAATATAACCGCAGTTGTTCGTGGGCCTTCTTGCAGAGAAAGGCTGCCCAACCTTGACGGGGCCATGGGCG
CTGCGGGAGGGCAAAAGACCACAGAGATCTGCGAAGCCAAAGTAAACAACGGGGTTGGGGCGGCGAGAATGAT
CAATAGCGATGCTCCGAAAGGACTCCGCGATAGGAATCGAGCGGGAAGGATTCCCTCCATCCTAACAGTCCAT
GGGTTAAGAGGCCGAAGCTTCCCTAAATACCACACTCCCGCGAGAGAAGGGACTGAGAACAACTTCTCAAACT
ATTCTCTCTCGAAATCGCTCCCTTCCTCGAAAATTCCATCTCTGAGACTCGGATGAGGTCCCCACCCCCTCCA
CCCTTGTCCCGTGACCGTCGCCCGCTCAGCCTCCCAGCCGAGTCCGCGGGGCCTGGGGCGCCCACCCCGCCCA
CCCAAGGGACCGCGCAGGGGTGAACTCCCCCGCGCCCCACCTGCGCCTTCCAGACCTCGGGCGCCCCGGCGTT
GCCTCGAGAGCTCCCTGCGCGGCCGCCGCGGCACGGACCAGCTCCCACTCCCTTACACTGGGCGCCGCTGCGC
TCGCCGGGGGCCGGTCCCGAGGTTCCCAAGGCCTCGCGCGCGCGCTTGCCGTGGCAACCAAGACGTTCCACGA
CGCGCGCTCTCGAACGCTTCGCGTCACGCGGCCGCGCGGCCCCGCCCGTCGGCCTCGCTCCCGCCACAGAGCC
CGCAGCACGCCGCCGCCGCAGCCTAGGTCACGTGAGTACCCACGCGCGCGTCTTGCCAGCGGATTCATCACCG
GCCTGCTCAGACTAGGTTCTGCCCACTCTGACCTTCTAAATGGTACGTGGGAGGACGTCCGTCCCCTTCGGAC
CCAAGAGTCACCGTAACACTCTAGAAGGGGAGAAAAGGAGCGAGGGCGGCAGGCGACAGAGAACCTCGCGAGT
CAGCGGCCCCGCGCAGACCCCCCCAGGCACGGTCCCCTGCGGCCACGTCGGCTGCTCGGCGCCTGCGCAATCT
CTTTCTCTCCAGCGAAACCGAGGCCTCCGGAGAGCCTAGTAGAGAGTGTGGGCAGTGAGCGCTTGTAGCCGCT
AGAGGGAGCGCTGGGCACAGTGCACG
CGI: 58 range = chr13: 57101588-57102323
CGCGGCATGTTCGTACCAGCGCGGGCAGAAACGGGCTCACGAGCGCCCTCGAATTCACACACACTCACCGAAA
TACACATCTCAGCCCGTGGAAGCGCATTCACACACACCCACGTACACTCCTCCGCACCTCATTCAGATGGGTC
CACGCGGAGTCAGGGCTGCGCTTCCCTTGGCATGGGCGTGTGTGCGGCGAGGGCGTGTGTGCGTGCGTGTGTG
AGAGTGTGTGTAGAGAAACCCTTTAGGCAGACCGCAGCTACGTTATTCTGCAAGCATACTGCGATTCCCGATT
CCGTGTATGTAGGACCACAAAAAAATTAAATCGCTGTTAAACTTTTTTTTGTAAATTCTCTTTTCCGAAGGAA
GGCGCTGGAAGAGCTACTCCCGGTGGTTAAAGGCCCGGGAGACCTGGTGGCGAATCCTGGGGCGCGTCCGCTT
TGGCGGAGCGCTGGGCTCCGCTAGCCGGACTGGTTCCCCATCTAACTGATCTAATCAATGACTCCGAAGAGCC
GGGGCTCCTGGCCCCGCCCCCGCCATCCTCTTCTCCGCCTCCCATTGGACGCGGGCCGAGAAGGCAGGGCCTT
GCTCCTCGCTCGGATTGGCTGACAGGGAATCAGTATCAATGTTTAAGCGGCGGCGTGAGGTGAATAGAGTCAG
TCAGCAAGAGACGCTGGGGAGAGAGCAGGGATCGCGAGCCCGGCGGATGCGGCAGCGGCGGAAGGCGGCTGGG
GAGACG
CGI: 30 range = chr13: 105943410-105943788
CGCCGGGCTCTGCGGGGGCATCTCCTGGACGATGTACACCGGGTGCCCGTAGTCGCCGCTGACCTTCTCGTAG
TGAGGGCAGAAGACGCTGTCCGCAGTCCTTAGCGGGATGATAATGTCACTGGGCTCTGAGCCGTTGTTGTTGC
CGCTGCGCTTGGGTGTGGCCAGTGTGCTGAGCGACAGCGTGGTCGTGTGCTGCGGCGAGTGCTTCCTGTGTCT
CCTCCGGTACTTCAGCAAGAGGACCACCAGCGTGATGATGATGACGATGAAGATGATGCATCCTGAAGCAATC
CCTGCAAATAAGGCCACTTCGGAACCGAGGATGTTGTTCCCCGAATGTCCGGCGCTGTTGCCGTCTGTGCTAG
AACCTGCAGACGCG
CGI: 74 range = chr13: 111763361-111764235
CGCTCCCAGCCGGCAGCCGCTCTGGGCGTGCACCCGCCACGCGAAGCCAGAGGTTGGACGACGCAGCCGGCCA
GGCGCGGCTCCCGGGGGACCCCGAAACCGCCTGTGGCTCAGGCCCTACTTGGCAAGAAGAGACTGGGGAGTGA
GAGGAGGGGTCACTCTTGCTCTCTCGCACAATAGACTTCCCGCAGGCGAGTGCGAACGGCCTTTTGCTTCCTC
CTTCTTTTCCAGGACCCTTAGCGACAGGAGAGGAAGAGAAGCGGCCCGGCGGTTTAATTGCCAATTTCCTGAT
GCAGCCACAGGGCCCAGCAGCGGCTCAGCCTAGGCCACCGGGTCCAGGCCTCTAGGCAATAGGCCCGGCGCCC
CCTCCAAGCACCGTTTCCCGCCGACCCCGCAGTCATCACTGTGAGCTCGAGAGTATGGGCAGCCTGTGGTGCC
CTGAGGCGCCGGGCGCTCGGCGCATCCGCCGTGCCCACAGCGCTGAGGACCAACTAGGGCTGCCCTCGGCCAG
GGGCACTGTGCCCGTTTGAGTGGCACTCGGACCTGGCGAGGGGTGGAAGCCCAGGTAGAGCTCGCGTCTTTAA
GAGCCACCCGACAGAACTGCGCGCTACATCTGCGCCAGCTGGGCTGGGTGGGAACAGCGCAGAAATACTCCCG
TGCCGGGGCGTACAGGGCAGGTAGGCCCAGCAGAGAGTCTTCTCGGAAAGTTTCCCACAAAAGAAGGGCCGGG
CAGGCCGAGCGGCAGGAAAAGCCGGTGCTCAGCGGCGAGGCCCGAGAGGTCTGGCATCCGGCGGCCTCCCAGC
TTTGCTCGGGTCTCCCGCCGCCTCTCTCCAGAGCCGCCCGTAGCTCCGTGGGGCGGAGGGCGCAATGCCCCG
CGI: 28 range = chr13: 112249708-112249928
CGATTCCTATCGAATCAACACGGCCATTAAGGACAAAAACGGGCAGGACACAAAAGCAAGCCTGGATGGCGCA
CCCTACAAACGAGTTCTGAAACAAAGCGAGTGCCAGACGCGCGTGGGAAAGACGCGCGTGGGAAAGACGTGCA
TGGGAAAGTCGCGCGTGGGAAAGTCGCGCGTGGGAAAGTCGCGCGTGGGAAAGACGTGCGTGGGAAAGACGCG
CG
CGI: 87 range = chr14: 19992581-19993863
CGTGACGTAAGTCCGCCGCGGGTTCGCCAGCACCTTGCCATCCCGCACCACGCCCACGCCAATCTTATTGGCG
CTGCCTTCAAAACCCAGCACCGCCGGCATGGCGGAGGCTGGGAGAAAACGCCGACAGGACTCCTGGCAATGTC
AGGAGCTGTGGAGGTCCTCACTAGTCCGCGCTGGGCCGCAGCTTTCCGGAGCGCAGAGGAAGCTGGCCAGCCT
GCAGATAGCACTGGGAAAGACACCGCGGAACTCCCGCGAGCGGAGACCCGCCAAGGCCCCTCCAGGGACCTGT
CTTCCTAACTGCCAGGGACGCCGAGCCAACTCTGTGCCTTACATTCGTATCCGTTTTCCTATCTCTTTCCCGT
GGTCCAGCCCAGCCTTCTCCACTGTTTTTTTCCCTCTTGCACATAGTTAGAATCTTAAGTCAGTGTCACACAA
TGTGCTGTGCATCTGGCACAACGATAAACAGCCCGAGGGAGGGTTGGGGACCTAAGTGTCCTAGAGAATTAGA
GGAGGGAGGCGAGGCTAAGCGTCTCCGTCACGTGGTGTCAGACAGACCAATCACGCGCATTCTTCGGCCACGA
CAAGCGCGCCTCTGATCACGTGACCAGGTCCGCTACCCACGTGGGGGCTCAGCGTGCACCCTTCTTTGTGCTC
GGGTTAGGAGGAGCTAGGCTGCCATCGGGCCGGTGCAGATACGGGGTTGCTCTTTTGCTCATAAGAGGGGCTT
CGCTGGCAGTCTGAACGGCAAGCTTGAGTCAGGACCCTTAATTAAGATCCTCAATTGGCTGGAGGGCAGATCT
CGCGAGTAGGGTACAAGGCACTATGAAATGATCTAGTTTCGTGGGTGAGGGGCTGAAGGGCCTATGATGCACG
GAGGCGGGGAAAGGATTTAGAGATAACGTGGTTTGAAAGGCGGGACCTGGTGCGGGGACGCTCTTGGGAGGAG
TCTTCTCCCCAGCCTTAGCTGGTTTCATGATTTCTTTGCGTCTGTAGGCAACGCGGTAAAAATATTGCTTCGG
TGGGTGACGCGGTACAGCTGCCCAAGGGCGTTCGTAACGGGAATGCCGAAGCGTGGGAAAAAGGGAGCGGTGG
CGGAAGACGGGGATGAGCTCAGGACAGGTAAGGGAATGAAATCAGCCCTTCTTCCTAGAAGCTGCGGCGGGGG
TGTTTGTCATTCCCTTGATGTACGGTAAGTACGGGCCGACTCATTTTTGCAGGGGTTTGTGAAGAAGTCGCAG
GAACCGTAGGCTTTCGTTGGGTCTATAGTTAACGCCGGATCG
CGI: 79 range = chr14: 23710894-23712060
CGCCTGTTACTAGAGGCGAGAACCGGAGCCCATTGGTCGGAACACCTCACAATGGACCCCAGCGGCGCGCAAA
ATCCTTATGATTGGTTTGCTGGCTGCCTCGGGAGACCCTGTTGCCAGGATACTTGGCGTTCCCGACCCGACCC
CCGTTCCCCATTGGCTGTCAGGGCAAAAGCCGCCATCTAATGAGGAGCGAGGTGCGGTGCCCCGAAGCGCTCG
CTTCCCGCGGTGCGATCTAGTCCTGCAGTAGGCGGCCCGGGGCCACACCGCGGCCGCCCAAGCCAGTGCAAGG
CCCAGGGGCCTGACATCGCTCCCAGCGCTCGAGGACCGAGGCCTGCTGTGGAGGACACCGTGCTCCCTCGGGA
CCTGCTCTGGATTCCGGCCCGGACGTCCCCTTGGAGCTCTGCATCTCCAACCTGGAACCCAACCCAGAAGTCT
CAAGTTTGACGCATCACGTGGCGTGCGGATCCACTGAGGGTCCACAGAGAGGGGCGCCCATCTCCTGCGTCTC
AGTTATCCTGGTAATTGTGTATCTGCCCATTGTTCGTTGCCTCATTAACTTGGCTTTCTAGGTGCACCCACCT
TGCCACCAGAGAAGTCCAAATCCTGACTTCTCTCCAAGGTGTTGGGAATTCTGTGCCCTAAAGAATTCCGACT
CAGATCCGAACGGGGATCTGGTGGAATCGAGGGTGAAAGACCAGAGGGACAATGTTCTACTATCCCAACGTGC
TTCAGCGCCACACCGGCTGCTTTGCCACCATCTGGTAAGGGCGGGGCCCGTTGGCGCGCGATGGCGGACGCTG
CCCGGGATCCCAGCCTGACAGCTCCCCCTCCATCCCCATTCTCCCACCTTCCCCACCCACTTCAGGCTGGCGG
CGACTCGCGGCAGCCGGTTGGTGAAGCGCGAATACCTGAGGGTGAATGTGGTGAAAACCTGGTAAGGCCCAGA
AAAGGGAAGGAGGGCCTGGTGCGGGGGGTGAGTTAGGGGATGGGGTGGCCAAGACTGTGGGCCCACTCCTGGA
CGCAGCGGTAATCAGGGCGCATTGTTCCCCAGCGAGGAAATCCTCAATTACGTGCTGGTACGAGTGCAACCCC
CGCAGCCCGGCCTGCCGCGGCCCCGCTTCTCCCTCTATCTCTCAGCCCAACTTCAGATCGGTGTGATCCGCG
CGI: 23 range = chr14: 28317076-28317375
CGTAGCGACGACGTGGTCCTTGTAGGACCAAGCATTCTTGGCATTCTGTCGAGATTGAGATTCCAGAGCATCG
GATGAACGGGACTTATAGCTAAGGCGTACTCACCCACCCCTCCCTTCGTCTTTTTACGCACGCAGCAACTCGT
CCTCACGTGCATAGGGGTAGTGGACAGTGTTGACTTGAATTGCTGTCCCTCGTTCCAAGCCTTTCCTGTGAAT
GAACCCGAAAACACTCGACAGGTCGTGAATAATCGTTTTAATGAGTGTGCAAAGCGTGCGACGGGGTGCACCG
AGCTGTCG
CGI: 147 range = chr14: 33338698-33340189
CGAGAACTCCAAGTCCGACGAGAAGGGGAACCAGTCCGAGAACAGCGAAGACCCGGAGCCCGACCGGAAGAAG
TCGGGCAACGCGTGTGACAACGACATGAACTGCAACGACGACGGCCACAGCTCCAGTAACCCGGACAGCCGCG
ACAGCGACGACAGCTTCGAGCACTCGGACTTTGAGAACCCCAAGGCGGGCGAGGACGGCTTCGGTGCTCTGGG
CGCGATGCAGATCAAGGTGGAGCGCTACGTGGAGAGCGAGTCGGACCTGCGGCTGCAGAACTGCGAGTCACTC
ACGTCCGACAGCGCCAAGGACTCGGACAGCGCAGGCGAGGCGGGCGCGCAGGCCTCCAGCAAGCACCAGAAGC
GCAAGAAAAGGCGGAAACGGCAAAAGGGCGGCAGCGCCAGCCGCCGGCGCCTGTCCAGCGCGTCGAGCCCAGG
CGGCCTGGACGCGGGCCTGGTGGAGCCCCCGCGGCTGCTGTCCTCCCCCAACAGTGCCTCGGTGCTCAAGATC
AAGACGGAGATCTCAGAACCCATCAATTTCGACAATGACAGCAGCATCTGGAACTACCCGCCCAACCGGGAGA
TCTCCAGGAACGAGTCCCCCTACAGCATGACCAAGCCCCCCAGCTCTGAGCACTTCCCGTCCCCGCAGGGCGG
CGGCGGTGGGGGTGGCGGTGGCGGGGGGCTGCACGTGGCCATTCCCGACTCGGTCCTCACCCCGCCCGGCGCC
GACGGCGCGGCCGCCCGCAAGACTCAGTTCGGCGCCTCGGCCACCGCGGCCCTGGCCCCCGTCGCCTCCGACC
CGCTGTCACCCCCGCTCTCGGCGTCCCCGCGGGACAAGCACCCCGGGAACGGCGGCGGGGGCGGGGGCGGGGG
CGGCGGCGCGGGGGGCGGCGGCCCCAGCGCGTCCAACTCCTTGCTGTACACTGGGGACCTGGAGGCGCTGCAG
AGGTTGCAGGCGGGCAACGTCGTGCTCCCGCTGGTGCACAGGGTGACCGGGACCCTGGCCGCCACCAGCACGG
CCGCGCAGAGGGTCTACACCACGGGCACCATCCGCTACGCGCCCGCCGAGGTGACCCTGGCCATGCAGAGCAA
CCTGCTGCCCAACGCGCACGCTGTTAACTTCGTGGACGTTAACAGCCCCGGCTTTGGCCTCGACCCCAAGACG
CCCATGGAGATGCTCTACCACCACGTGCACCGGCTCAACATGTCAGGACCGTTCGGCGGCGCAGTGAGCGCAG
CTAGCCTGACGCAGATGCCCGCCGGCAACGTGTTCACCACGGCCGAGGGACTCTTCTCCACGCTGCCCTTCCC
CGTCTACAGCAACGGCATCCACGCGGCACAGACTCTGGAGCGCAAGGAGGACTGAGGCGCCGCCCGTCCTGGG
CCCGGCCAGGCCCCGCTTGGAGGAGGCATCGTCGGCATTTTCGTTTAGACCTTTAATTCTAGCACTTTGAATT
CGAGCAGGTCAGCGTCTTCTCTCGCCACGACG
CGI: 22 range = chr14: 36122289-36122589
CGCCCGGCCGCTGCCGATCTCGGAGCTCGGAGGCCGAGCTCCACAAATTTGGGTCCAGGCCCGCTTTAGAGCC
CCTGGGCGGGGGCGCTTCTCAGGGCATCCTGTGAGGGCTTTGAGGCCTCCTTGGAGTCGCCAGATGAACTGGT
GCCGCCTGTGCGCCTTGGCCCCATAGCCTCAACGGCACTCTCACTGCCTGGGCTTTGGTCTTTGCCCAGGAGC
CTGCCCATGGCCTACGCTCCCCGCTCGCAGCATGGCAGACCCTGACGAGGCTGCCCGCCTTGGTCCGGGAATG
GACCGATCG
CGI: 123 range = chr14: 37137198-37138958
CGGGGCAGGGTACCCGCGAGGGCAGGCACGTGGCGGCTCCTGCGGTGTCCCGGGTTAAACTTGCCTGTGTTTA
AGACGGGTCTGCGACAGCTTGGGGCGGTCCAGGTCGCGGGGAGGGCGGGCTCCTCAAGTGGGGGATCCGCGGC
AGTGAGGACTGTAGGGTGCGCGGGTACTCCGGGTAGCCGCCAGCGGAGGAAGCGGCTCCGCCCTTCCCGGAAG
CTGCCCTTGCTACACCCGTGGGGCCTGCTCCCGGCGCAGTCCCGCAGTACCTGAGCGGCACTCGGTCCTTTGA
CCACGCTTGGCTGCCTCAGCTTACACTTCCCAGCAGGATCTGGCTGGGAGCCCCTTCCTCAGATATTCACCAG
GCAGGTAGAAGCAGAGGGAGACGACGGCGAAAGGTGGAAGGAGAGGCCGCGGCCTCGGGCCTCGGGCCCCGGG
CCCAGACGGCGGCCTCTCGCGGCGACAGGGTCCTTCCTATTTAGCAGGACCGCAGGGTTGGCAGACAGCAGGG
CCTGGGCCGGCGGGGCTCTGCGGTGCCCATTCGAGTCTCTCCAGGGCTTCCCTCTGTGGCTGTCCCTCGCCTG
CCCCCTTTCCTTGCCTACCCTTCCCTGGACGGGGTTGTTGTCAGGTGACGGCTTCAGCAACCCAGCCATGCTT
GGTGTGGAGTGGTTCGAGTTCCTCCGCGGGCCCCCACCCCCCACCCAGATAAGAAGCTTAAGTCCTCCTTCTG
CAGGGGAGAATCGGATGCAATGAAACTAAGACCTGTGGTCGTTAACGCGGTTCAAAGCCGACCCCAACTGGGA
CACGGCTCAGCTTAGAAGTGAGGAAGGCCTGGGACGCTGGAAACAAGGGGTCACACGTGCGTGTGCCTGGCCT
TCGCAGGTGGATGTGTGCGCCGAGCTGGGGAAGGGGCCAGGGAGCCGCGAGACTGCGGTCCCCCGCGAGAGAG
AAGTATGGGCCTGGCCAGGGTTCGAACTCCGTTCCTTCGCTGCCTTCCTTTTATTTTTCTTCCTCATCTTCCT
TCCTCTCTCCCTTGGTTCCATCATTAAATCTTTAAGGGATTAATTCACAACTCTGTAGTAGGTAGGGGCCCTG
GGACCACTTGACGGGCCTTTGCAGGCAGTTCTGTACAGAGTCCTAACCCGTAACGGGCCTCAACCCCGGCTGT
GTGTGCGTGTGCTTGTGTCTGTGTGTCTTTGTGTGTAAAAGCAACGCATAAACATACCCAGGGCTTTCACTTA
TTTTATTGAAGCAAACAAACAAAAACAGCCACTGGGTTTGTCTTTTCCCCTACTCCTGCCTGAGCGCCGCCGG
GTTTCTGAGCTGCTCCGGGCGCGGACCTAGCTCACCCGCAGCCGGATGTCGGAGCCGGAGCTGCTCCCCACCC
GGCCTCGCCCGCGGGCGACAAAACCGTCCCTCTGGCCACGGGAGAGCATCGCCTTGCCAAAATCAACTCGCAT
TTTCATGTATTCAAATGAGAAAGACTGAGAAGGGCGATTTCCCCTGCTGGGCAGTCGACAGCGTTGGAAGGAA
GAAGTGCCCCCTAGGGCCTCGCGGAAACGGGAACAAACCTCCCTCGAGGCCCCCGGAACCGATATGGCGACCC
CGCCCAGACCTGGGTCCCCGCGGCCGCGCGCGTCTCCCGCCGTTGTGGCCCCCGAGTTACTGACTTTTGTTCA
CACCGGTCAGCGCCTGTTGGAGGACGTGCTCAGCCCCAGCCGGTCCCTCCTCATCCAGCCGATCCCCCTCCTG
GGGAGCGCG
CGI: 20 range = chr14: 56347822-56348040
CGGGCCTCGAGGATGCGAGTGTGAGGTCGACAAGATATCGTGGAAGAGAGCGAACGAGGGAGGCCCCCGTTGG
AAACAGTTTCTGTGTTAGAACAAACGCCACCAAACGACCGACACTGCGAGGCCTGGAGCTACCTGGGCTGGCG
CCGCCCGAGCCCCGGGCTGCGAGCCCAGAGGCTGGGAAGTGATGGGACCTGGGGGCCCGAGCCGGAGAGTGCG
CGI: 178 range = chr14: 60045486-60047933
CGGCGGGCGCTGTCGAGCACGGGGAGGTGCTGAAATAGTCCTGGCGTGCTGATTCAAGCTTTGATTGGCAGAG
CCACCCGGTGACTGACAGGGGGTCTCCATGGCGCCCGCGCCGCCAATCCGCCCACCCCAATAGCGGAGCCAGC
TCGCCTGCCGGCGTGCCTGAGCCGAGCCGAGCCCGAACCCCAAGCCGCGGAGCCAGCACCTCCTCCAGTCGGG
GTCGTCCGCTCCCGGCCGTTGAGCCACCGCCGCCACCCGGTAGTGTGTCCCGCTGCCCCAATCCGCCTCATCA
ACAAGCGCCTGGCACACTCAGCCAGGCCCGCGGGCATCTGCTGCGTGTCCCGCTCCGGGCTCAGTGCCCTCGC
CGCCGCCGGCACTGCCTCGATGTTCCAGCTGCCCATCTTGAATTTCAGCCCCCAGCAAGTGGCCGGGGTATGT
GAGACCCTGGAAGAGAGCGGCGATGTGGAGCGCCTGGGTCGCTTCCTCTGGTCGCTGCCCGTGGCCCCTGCGG
CCTGCGAGGCCCTCAACAAGAATGAGTCGGTGCTACGCGCACGAGCCATCGTGGCCTTTCACGGTGGCAACTA
CCGCGAGCTCTATCATATCCTGGAAAACCACAAGTTCACCAAGGAGTCGCACGCCAAGCTGCAGGCGCTGTGG
CTTGAAGCACACTACCAGGAGGCTGAGAAGCTGCGTGGAAGACCCCTGGGACCTGTGGACAAGTACCGAGTAA
GGAAGAAGTTCCCGCTGCCGCGCACCATTTGGGACGGCGAACAGAAGACACACTGCTTCAAGGAGCGCACGCG
GCACCTGCTACGCGAGTGGTACCTGCAGGATCCATACCCTAACCCCAGCAAAAAACGTGAGCTCGCCCAGGCA
ACCGGACTGACCCCTACGCAGGTGGGCAACTGGTTCAAAAACCGCCGACAAAGGGACCGAGCGGCTGCAGCCA
AGAACAGGTCGGTACCTAGAGGCCTCCGCGCTTTGAGCGCACCGGGGAGGAGGCGGGTGGAGGCACCTCTGGC
GCCCTTACCCAGTCCCTGGCGACTCCAATTCAGCAGGAGTTGGGAGCGCGGTCTGTCTTGGGTTAAGAGCCCT
GCGTTCTGGGCTCCTGGCCGGGAGTTCCCTTGCCGGCTCTGCTTCCCCACCCGCTGGCTCCCCACGCCTGCGG
GCAGCTGCAGCAGCTGGTCCCGGTCACCAAACCAAGGCTTCACTGGGACGGAGAGGGGAAGAGAAATAAAAAA
TTAAAATCCTACAAACAGTTAGGGACCCCAAGACCCAAAGCTAATTCTTGTCAGCCTGGGCACAGGCTCCTAC
TATTAATCGAAGCCTGGCTTATTAGCAATGTGTCGGTTTCATGTTAATTATCATTTTCAAAGCCCAGGTATAT
CCCTCCCTAATGCTTTGAAAACAGTTTTCAATGGACTTTTGAGAAATGGGAAGTCGAGTTTTCCTCTTCCCAT
GCGCTGCCTGCCACTCTTGTCTCAAAACAGCAAACTAGTCCGTGGGCCGAGGCTTTTCGTTTCCCGGAGTGTG
GATCTCGATTAGCCAAACATTTTGCGGAAGAGCCCGGCCTCATCCCCCAGGCCCAAATGCTCCTTACAATCCT
TTTTGCCTTTAGGTCGGGCCGACCCGATCCAACGCGATCGCGGGAGCACTTGCTCAGGCGTAAGCCCCAGGCA
GACGCACCGTTAGAAATGGTATCCCATGTCCCTGGGACCGATCTGTCCTTGTCACCCACACTTCGTTTATTTC
CTGACAGTCCTGTAAATCTCCCAAAAGTGCACAACAAACAGGGAGGACACTGCAAGCCCAGTATATAAAAGAC
CTGGGAGCTGCGGCGCTGAGAAAGGGCGCGAATCATGGTGGGGCACAACAGTAGGGACCCGCGGAGGGGCGGC
CGCGGACTCCTGCCCGACCTCTGTCGCCTTGCCGAGTAATCCTCGCCTTAACTGCTGGGGTCTTCGGAAGAAC
CTCTAGCCGCCGGGCTGGAGGGACGCAGGAGGTGGTGGGGGCGGGCGACGGGCGGCTGTGTTACGAGCTGTGA
CCCGTGTTCCCTTTCTTCCCCGTAGACTCCAGCAGCAGGTCCTGTCACAGGGTTCCGGGCGGGCACTACGGGC
GGAGGGCGACGGCACGCCAGAGGTGCTGGGCGTCGCCACCAGCCCGGCCGCCAGTCTATCCAGCAAGGCGGCC
ACTTCAGCCATCTCCATCACGTCCAGCGACAGCGAGTGCGACATCTGAGTTGCCCATCCAGGATGCTCAGAAG
CAGATTCCAGTGTAAAAACGAGAAAAACAAAATGAAAGAGGGGAAGAAGATGAGAGACCTGCAAATCCAGCGC
CACAGAAGCCAGGTGACCAGGGACCCGCGGGCTCGGGTTGCCGTTTCCCGCCCCACCCCGCGGCCGGCCTGGC
TTCACTGGCGCCCTTTGGCCGCGACCACGGGAACCAGCG
CGI: 54 range = chr14: 60173732-60174416
CGGCTAGGCTGCGCCTGCATCAGGCGTGGTGATTGGCAGGCGCCTACGGCCCACGCAGAGATGGCCGCGTGGG
GGTCGGAGCGCCAACTTCTCAGCTCCCCTTCTCCCATGACCCTCACCCCCCACACCATCTTCAGCCGCCCACT
GGGAGCTTCCTCCACCCCTACCCCCCAGTGCCGGCGAGGCCCCCTGGCAGATGGAAGCTGCTGACTGATGGGG
GCTGCCGAGCGCGAGGGAGCTGAGTGAGGCCCTTGCGCCCTAGGCGGTTGCACCCCGGACCCCTGCAGCTGTG
GACGCCGGAGCTGTGCGCAGTCATCCTGAGCCAGCCCGCGGGGCCCGATCGGAAGGGACGCCTCTCCTAAGAG
CTGGCCTGGAGTCCTGGAGCCTCCAAGCGGGCAAGTAGGGGCCGCAAAGGCTGGGCTGGGCCTCCGCTGAGGC
CCTCGGGGGCCTCTGGGCCCTCATGGCCTGGAGGCCGCGCGGCCCAAGCCCCTAGAGCAGAGGCCGCGCTAGC
CTGCAGGGGTCGACGCAGGGCCGGAGGCAGCGGCTTTTCCTTCCCACTCCGGGTTGACCCTAAAGACACGATT
TAACGTGGCGGCGGCAGCTGCCCACGCTGTCTGGAGGAGCAGGGCGCCTGGGATGCGGCGGCGAAACTGGCCC
GGAGGGGGGCCCAGGCCTCACGCGCCCG
CGI: 133 range = chr14: 98781593-98783184
CGGAGGCTCCTTCCGTCCCGGCCTCACCTGGATCCCGGGAACCGCCCGCTCTGTCCCGCCAAGGTGGGCTGAG
GAAGACGGCGCCACTCATCAGGGCAATGGCGGCGGGCGGAAGAGGGATCCCCGTGCGCCCCCAGCACCCGGGA
CGAATGCCACCCCGGCGAAGCGACCCGACCGGCGCGCACGGTTTCGGGGAGGGGACCACTTCCACATTCCCCA
TGCCCGAGAAGGTCACCCACCCGGGAGAGCGCCCAAGGGCCAGAGAGGAGGCGACTGGTGGAGGAGGGGCGGC
CCCGTGCGCACAAAGGGGCCCGGGGCCGGCAGGCTCCCCGCCCTTGACCTTGGGTCTCCGCCTCCATCCATCT
CCGCCGGCTGCCAGGGAAGGGGGCTGGCCCGGGGCCAGAGGCGTGCTCGCTGGGCTGCTGCTGGGCTGGGGAC
CGACGGGGGCGGGGGGGAAAGGAGCCGGGAAAAAAGACTCCAGGGCTGCAGAGTGCTCCGAGGAAGCCTGCAT
TCCACCACCTTCAGGAGCCGGTCCCGAGGCGGCTCCGATTCACTGCATGCCCCCCGCCCCCCAAAGCAAAAGT
TGCACGGATGCACGAGGGAAACCCCTTCCCAAAGCTAGCCCTTCGACTCGCCCACCCCCCGCCTTCCTCGGAC
CCAGGCCGAGTGGGGGAGGGGAGTGTCAGGGGAGGAAGAAAGGAGCGCGCCTTCCCAGCGAGGCCAGACGCGG
GCTGGGTCAGCTGCGCCTCCGCCCGCCCCTCGCCGCCCGGCTCAGGCAGCTGCTCCATTAAGCCCCCGAATTA
TGCATGGACCTTGAGCCCTCTCGGCCCTCCCGCCCCACCAAGGCACAATCAACGTGCGCAGCGGGCGCGGGTC
AAAGAGAGAGGGAAGGAGGTGGACGATGGGCGCAAGGCCGTGGGCGAATCAGAGGCCGGCGGCCAGGCGGGGG
CCAGGCGCGCCCGCAGGCCTGGGAACAGTGCCGAGGAGCCTCCCGACCCGGCCAGGGCCAGCCGGGAAAGGGG
CACCGCTCGCAGGGGAGGCCCCCGCGCAGTTTTGAAGTTGCCAAAGTGTCCGCGCCGTGCCGGGTGCGGGGTC
CGGGAGATGCAGCCGCCCCCGCGGAGCTCTGCGCCCCTGGCCTCGGGGAAGGCCATTGTGTTCTCCTGTGTGG
CAATGAAGGGGGCTATGGACCCCAACCATTGAGCCCTTGGAGGGAGGGGCCTGAAGACCCCTCGGGCAGGGCG
GGGGAGGCTGTCTTGCGGGCGGCGGAGAGGATGGGTATGATTTGCTCGGGATAGGCACCGTCGCGGGGAGGGG
AGGAGGCCAAGCTTGAGGAGGGGCTGCTGGAGATGGAAGGAAGTGAGAGGAGACTTGCAAGTTGCAAACGTCG
GGGAAACCGGAAAATTGCAGTAGCGGGGAGGCAGGTGGCGCCCAGAGGTTCGAAAGCAGAATTGGGAGGACTT
CGATGTCCACCTCGCAGACAGTGACCCAGGCCCCAGAGGGCTCCGCAGCCTGGAGCCTCGCGTCCCGCCTCCC
CGCAACACGCTGTTTTCAGCGTTCCAGACCACAGCGCTGCAGTCTACGCTGCCCTGACG
CGI: 248 range = chr15: 50867751-50870991
CGCCAAAAGAATGAGCGCGGGAGGGGGTCACAGCAGCCAGTTCGGCCAAACATCGACGCTGCTCCGGCACGCT
CCAGCCCAGCGCCTGGGATGTGTCAGAGGTACCTGCGAGGAACATTTGCGTGCGATTCCACGCACGCGTTGCA
TCCCTCTTCCCAAACCCGGATCGCTGAACTGAGAGGTGGCGCAGAGTGTCTCACCAGGTGCGGGGATTTCTCT
CCGCCTCAGGCCGTACGAGCTTCCCTCGCTGTCCCTGAGCGCAAATGAGCCTCTTCAGTCGCCGAGGCCCGGC
CGCTTAGCTCTCGGAGCCTTCCACAGCCCAACACCCTGAGCCCTGGAGTAGGCAATTTGCTCCCACAGCCCTG
TGCTGGCCCTTCCAGGCACAGGGAGTCCCCCTTCTAGGGGTAGGGGCGGGCGGGATGAAGCGCACCCAGCCCT
CTCTCCTACCCTTCCTCCTTTGGTCCCTTCGGCTTTCGTGTACCTTATCTCCCGCGCGCCCAGCTCCTTGGCC
GGCTCACCTGCTAAGCGGAGCGCGGACATGCGCTGGAACTCCGGCTCCTGCAGCCACTTCCACATCCTCCGGA
AGGTCTCCCGGCCGGATTTGAGTTTGCTCCAGGGTTTGGGGTTGCGCAGCAGGTCCGAGAGGGTCCCCTGGGA
GCGGCAGAGCACCCTCTGCGCGAAGATGGCCTGTGGGATGCTGTAGCGCTTGAGCTCGGTGGTGATACGCTGC
GCCACCTCTTTGGTATTGATCTCTTCCATCTGCCCTGAATTACTTCCATTGCTGACCTGCGCGCCGGTCACCG
AAGGGTTGGGCTCCCGGGCTGTGCCCAGGAGTTGCCCGTGGCCCTGGGCGTTCAGGTGGGCGTGGGGATGGTG
CGGAGGAAGGCCGTTGATGGGCACCATGCCGGCCGAGGTGGGCGTGAGGTGCTGCTCCCCGTGGCGGCCGAGC
ATGGCCGGGTGGTGGGCTTCGAAGCCGTTGGGGGTGAGCATCTTGTCGGTGGGCATGGCGGCCCCCGGGTGGG
CATAGTGGGGGAGCCCTTGCTGGGAGTTGTGGATGCTGCCCAGACCGGAGCTGGAGAGGGGCGAGAGGCTCTG
GCCCATGCCGGCCACGTCCTTGTGGTAGGGGGTATAGAGGTTATTCATGGAGGCCAGCCCGCGCTCATCCCGC
ATGAGCGTGAAGCTACCGCTCACGTTGCCCGCCAGGCGCTGGTGGTGGTGCGGGTGGTGGTGGTGATGGTGGT
GGTGGTGATGGTGGGGGAACTTGTCCGAGACTGTGGAGATGGGAGGCAGCGGCTGCAGAGGGGTCAAGGTGGT
GTAGGTGGTGGGCATGCTCATACCTGGGGGAGTCTCGCAGGCCATGGTCATGGTGGGATGCAGGGGGCCGGCC
AGGCTGTGCTCAGGGGCCCGGTGGTGGTGGTGGTAATCTCCGCCGCCGCTGCCGCCGTCCAGCAGGGACGCCA
TGCCCATGGAGCGCGGGTGCGCGGGGGGCAGGTGGCTGCCGCGGTGCGCCACGGAGCTGCGCGCGTGGGGGCT
GCCGCCCAGCAGGTCGGCAGGGGCGGGCACCGGCTCATGGCTCACCCCGTGCAGCTCGCCGATCGCTTCCATG
GTCAGCTGCGCGTTCATCGTGATCCGGGCGAGCAGGCGGCGGACACAACATCGATGTGGCCAGGCAGAGGCGG
CGAGGGGCGCACGGAGTCCGGTCTTCACATCGGCTGCTGGCGACTGTTGCCTTCCTTCCTCTCACTGTGGGGC
TCTGTCTCTCTCTCTCTCTCTCTCCGTGTGTGTGTGTCCGTGTGTGCGTGTGCGTGTGTGTGTGTGTGTGTGT
CTCGCCTTCCCTCTTACCCCCCACCTTCCCCTCTGCGTCCTCGGCTTTTTTTTTTTTAATATTAATTTCCAAA
GAGGATCCGCGCCGTTGGGAGAGCGCAGTGCCCCAGCCCGCCCGCCTCGGCCACCTCTCGCCCCTCTCTTTCT
TAAAATTCTGAGGTCTCCGGCTCCCCTGCCGCGGCCCGCGCGCCTGCCGCGTCTGCTGCCTGCCCGCCCCGCT
GGCCAGCTTGAGCCATGGCTCTGTTACTGTTACAGACTCTGTGGCCGCGGTTCGGTAGCCGCCGCCGCCGCCG
CCGCAGCGGCCCGCCCTCACGCCCGCCAGGCGCAGCGCGCATGCGCGAGGCCCGCCCCCGCCCCCTAGGTCGC
GGCGCGCCAGGCCCTTGGCGTCCCGGTACAAATGAAGGAGGGGGCCCAGCGCCTTCCCTGCGGCGCTGGATGG
CCAGGGAGCTGCGGGCACGTGCGAAAGATTGGCGCAGAGCGCGACCTGGGGCCGCCGCTGCAATCCCAGGAGA
CTCGCGCCTGGCTCGCTCGCCTCCCTTGCTTGAGTGGGCTCTGTCCTCCCAGCCCGGGGACGCTCGTGTCGGG
CTTCTAGCGGCTGGAGTGCTGTGCTTGGAGACATCGCCCCTCTCTCTCCAGTTGCTGCTTCCCGGTGCAGCTT
GCCCGGGGAGCTGGGGACTGTGTCATCACCCCTTCGGCTCTAGCCCACTAAGCTTTATTTCCCGGGGGGCTGC
TGGGAGTGCGCTTTCCCACCCTTGAATTCACGGCCTATTGGGGGATGGGGGTTGGGGTGGGGTGGGGTGCAGA
TTGCTTAAAGGGCTGGGTCCGTTTGGCGGCCGTTGACCCGGCACCCTTCGTCCTCCCAGATACATACTTGCCC
ACCCTTTCTCATCCATGCCCTGGGGAGAGGAGTAATCAGTGCCAAGAATCCCAGTTCGGGCCATACCTCACTG
TCCCCCGCCGCCTGGCTCCTTCTCCCGCTCAGCTCATAATTAAGGCTGTGCGTCCGCTTCGCCGATGACTCGG
CCTGTGGAGGGGGGCGAGGGAGAGCGGAGGGAGTGCCCTGGAGGGTACCCATGTTAACTTCCGGGTGCTGGTG
GGGCCGTGGAGGCTCGGGCCGTCCCTGCGGTTACTCCCAAGGCCCTCCTGCTAAAGCACCCGGAGGCGGTTGC
TTTCCAGAAGTACTGACGCAGACAGGGTGGACGCCGGCGCGCGGGTCTCCGCTTGGCCCCTAGGGACGCCCTT
TTCCCGGCGTCCCCGAGAGACGCCTCCAGATTTGAAAATCAATTCAGCTTCGGGAGTAATTTCGCCCTTCCCA
CAGTCACGCTCCAATCTGGAATCGAACCTGGTCTTTGGGCCTGGTGGGGACGTGTGCGGAGGCCCCCAGTTTG
AGACGTACACCCGGCCGCCACATGCCGCG
CGI: 226 range = chr15: 58083428-58085812
CGCGCGGCTGCTCCATCTGTGAACGTGAGTGGTCGCCTGGCTCCCTCTTCCGCGGCGGCCGCTTCCTCATACC
TTCACACGGCGCACACCGGCCGGCGCGTCCAGCTGCCTGCCCAGTGGCCGAGGCTCTTCCCCCTCGCCCAGTC
TTGAGCTGGAAGTGATTCCTATTGGCCAAGGTGTCCATGTAAATAGGTGTGAAAGAAACCAGAGCTGGCCGGG
CTCTCCCTTCTCGCTCAGTCCCCTCCCTCTGCAGCCCCCGCTCCCCCTCCTCTTCCTCCTCCTCCCAAGGCGA
TTGTCATATGATAGCTAAGAAGTGGCACATTAATGAAGCGCCGCTACAGGGGTCTTTTCTGCTCCTGTCACCG
CTTAAAACTATCAGATGGTTCGAGGGAGGACATGGAGGCAGCCACCTAGCTCAGCGGAGACGCGGAGCCCACA
GCAGCGCCCTCCGGAGCCCTAACACGTCGCTGCCACCATCCGCGCCGGGACTCCGCAGCCGAGCTCGGCCGCC
CGCAGGACGCTCCAGGAGCGTCGCGGACCGGGCGGCACGGGACGCTGCGGGGCTGAGCTCAAGAGCCCAGGTT
CGCGCCGAGTCCAACCGGACCCGGACGCTGCGCGCGGAGTGCGCGTCGAGTGCGCGCCGAGAGAGAAGCGGCG
CGCAGCGGCGTCCTCCCGGATGCGGACGCGCAACTTGAAGCAACTTTAAGGTGAGCAGCTCTCTGTTCCGTCC
CTGCCCCCTATTCTGGCCCCAGTACCGACTTACTTCCCGGCTATCCTCGCGCCGTTCGCCGGCTTCCCCTCCC
GCGCCCACTAAGCCCGCAAAGTTGCTGGCGAAAGAGTCCGGGCGCTGGCTGATCGAGCGCCGCAGGCCCCACC
CCCGACCCCCGAAGTCTGTTACTCGGTCTGGCTGACCCCGCCGGTGTCTCTGTGCATCCATGCTACCTTTCCC
TATTACCCACCCCCTTCCCAGATCCGAGCAGTCCGCCGGCCCGCGCGGACCCAGAGCAAGAAGAGGGCGAGGA
AGAAGATGCCTCGGCCCGGCCGCAACACGTACAGCGACCAGAAGCCGCCCTACTCGTACATCTCGCTGACCGC
TATGGCCATCCAGAGCTCTCCCGAGAAGATGCTGCCGCTGAGCGAGATCTACAAGTTCATCATGGACCGCTTC
CCCTACTACAGGGAGAACACGCAGCGCTGGCAGAACAGTCTGCGCCACAACCTCTCCTTCAACGACTGCTTCA
TCAAGATCCCGCGGCGGCCGGACCAGCCAGGCAAGGGCAGCTTCTGGGCGCTGCACCCAAGCTGCGGGGACAT
GTTCGAGAACGGCAGCTTCCTGCGGCGCCGCAAGCGCTTCAAGGTGCTTAAGTCCGACCACCTGGCGCCCAGC
AAGCCAGCCGACGCGGCGCAGTACCTGCAGCAGCAGGCCAAGCTGCGGCTCAGCGCGCTGGCGGCCTCGGGCA
CGCACCTGCCACAGATGCCCGCCGCCGCCTACAACTTGGGCGGCGTGGCGCAGCCCTCGGGCTTCAAGCACCC
CTTCGCCATCGAGAACATCATCGCGCGGGAATACAAGATGCCTGGGGGGCTGGCCTTCTCCGCCATGCAGCCG
GTGCCCGCTGCCTACCCGCTCCCCAACCAGTTGACTACCATGGGCAGCTCGCTGGGCACCGGCTGGCCACACG
TGTATGGCTCCGCCGGCATGATCGACTCGGCCACCCCCATCTCCATGGCGAGTGGCGACTACAGCGCCTACGG
CGTGCCGTTGAAGCCGCTGTGCCACGCGGCGGGCCAAACGCTGCCCGCCATCCCCGTGCCCATTAAGCCCACG
CCGGCCGCCGTGCCCGCGCTGCCTGCGCTGCCAGCGCCCATCCCCACCTTGCTCTCGAACTCGCCGCCCTCGC
TCAGCCCCACGTCCTCGCAAACAGCCACCAGCCAAAGCAGCCCCGCCACCCCCAGCGAAACGCTCACCAGCCC
GGCCTCCGCCTTGCACTCGGTGGCGGTGCACTGACCCGCAGGAGCCCACGCCCCCTCTCGTTCTCCTCCCCAC
CACCTCACTCGCCTTCCCTGGCTCCCAGTCCTGCCGGCCCCCACCTGGGACCGCCACCCTAACTTGTTCATTT
CACCTTCGGCCAACCCGCCTTGCCCCAAGAGAACTTTGTTTTGGACCCAGGAGACCAAACACAAACTTGCAGA
TGGGCCGAGAGGCGCGTGGGAGTTGTCCTCGCCCCCACATCAAGGAAGGCCGGGGCCACCTGAGCCGAACCAT
CCCCTCCCTGAGGCCCCGAAACCCCCTCCTATTTGACCGGCGGGGGAAACCCTGTCACCCCCTCTTCGCCGAG
AAAAGCGCGTCTTCCCTCCGCCCAGATCGGCGGAGCCCCGAACTCTGCG
CGI: 22 range = chr15: 62984853-62985116
CGCGCCCCTCTGGCCTCCATCACTGTCGTGCCGGTCGTGGGGACAGATGGGAGGGAATTACGGTATTTACAGC
TGCTCTTCGCCGGCTCTTGCTCCCCCGCGTGTCGACAACCGAAACTGCAGCGAGGCCCAGAGGCCTCTGCCCA
CTCCCCTCGGAGTTCCAGGAGGACGCTAAGCGCGAGAAGCCAGGCTCAGGGAAACTGAACGCCCATACGCTCC
TAGTCCCTCTCACCTGGATCCTCTGCGTCAGGTTACGTGCTTGCG
CGI: 541 range = chr15: 65902540-65909629
CGGGACGCAGGTGCAGGGTGCTGGACGCAGGTGTGCGGCCGCTTACCTGGGGCGTGCAGGCCTTGGGCTGCGG
GGAGGCGGCGGGCGCCGCGCGTGGCCCGCGGGCGGGCGGACCCGGGGAGGGCGCTAGCGACTGCGCGGGCGGT
GGGTGTGGCGCCCCGGCTCTCAGCTGTCAGGCGCGCCTGCCCCGCCACTCGGGCTGTGACCGCGCCGTCCCCG
CCGCCGCGCCATGCGCTCCAGGCTTCGGCCTCTTCTTCCGGCCAGTCCCCGGCCTCGGGGTCAACGGCTCAGG
GTTCGCATCTCCGCGCCCGGGGTCCCGGCGCCCCGTGCCCGCTGAGAGCGGGAGGGGCCGCGGGTGGGAGCGC
GGAGAACCAGGGAGCACGGCTGTGCGCGCGCGCGGGGAGGGGCCGCGCCGTCACCCGGAGAGCCCGGCGGATC
CCGGACTCCCGCCCGCCGCTCCTCCCGCCGCGCACCTCCGCTCACCGCTCGCCCGGCTCCAGCCGCCGCCGCA
CTGTGAGTACCCACGTCCGGTAGCCCGCCGCCCCCGCGCTCTGCTCCTGCAGCTTTTTTTTCGTTTAGTTCTG
ATTTGGGCTCCTGTGGCTGTTGTTTTTATGATTATACCTAAAGACACCACCGCCTCGCTCCCACCACTGCCAG
TCTCCCGCTTCGCTGCCCTCCCCAAGCTCGTCCATCTAGCTCCGGGAGCCGACGGGGGTTCCTCAAGCTGCTC
TGGCTGCTGCTCCTTGTCGCTGCATATGGCTCTTCGCCTGTGCTTTCCGCTTTGGCCCCCGAAATTCCGTTCC
TTTCCTAGGGACCCCCTTCTTCTGACTCCGGGCCCGGACCCCCCTCCTCTCACTCAGGGAAAACCGCGCAGGG
ACCCAGGACCCTCAACTGGGGTACGCTCTCGGCTCGGGCGCTGTCTTCACTGTATGCGGGCCAGGCATAGTTG
CCGATTTCGAGAAACCGAGAAGCTGTCATTTCCCAGCGCTGCGCGCCCTCCAGCCACCTCCAGGAGGGCGCGA
GGCTTGTCAGCCGGGGAGTTAGGACAGTGTTTTTGCCTCCTACAATGATATAAAGGACTTCAACGCGAAATAA
GGGTCAACTTATTTTAGTTCGATCCTCGGAGATAAAGATGAAACAGACAGATAATACATAAATAGCTTGATAC
TTGAAGAAGGTACAAAACAGATGAGAGAAAGAGGAACGAGCCGGCAGAGACAGCTCAGGGACAGATAAGATCG
ACAAATGAGGGTCTCCTAGACAAATAGAGAAGAAGGGAGAGAGACAGATAAACAGAAGATTCCAGTCTCCTTG
CTGAAGGCTTTTGAACTGGGATCCCCTGTCTGGAGCTGCCCCTCTGAAAACGGAGTTACATTCAGGGCCGACT
GCAGGGGAGGAGCCCTCAGGGTTGGGCTGCCCTGGCCGCAGGAGCGCCTGCAGCCTTGGGCCGGATGGGAGCC
TGGCTTGTCTGAGGACATGTGGCTGGGTCAGGCGACCTAGAGGGCCCCAAACATCAGTCCCCAAGTACCCCCG
CTGCTGAGGTCTGCCTGCACAGCTCCCTCCCTGCCTCAGCCAGAAAGCAAAGTGCAAGGACCAGCAGCAACTT
GTGTGCCTGGAGCCTTGCAATGGCTACGAAGATGGCTGAGATTCCTTCTAGCCCATATGAGCCGGGACAGCGA
GGCATGAAGGATACTCAGAGAGGTGATGCCCCTCAAAGAGGAAGCCCAGAGCCCCGAATCCTGCAGTTGGCCC
GAGTGGGAAACGTATATCTGAAGGAGGAAAGCTCAAGGAGTGGGCGACTGGAAGCTAAGAAGTGGATCCCAAC
AAAGTTCCTTGAGAACCTCTCTGTCCCACACGTTGACCTCGGTGGAAACCAGCTTTGGTCTGGAATACAGCTA
AAAATGCAGAAAATGTGGTTAGAACTGCAGGATCCTGGTCTCACTAATAGCTGGAAAGAAAACGGTTTATATA
TCCAGCCGAAATCTTTCTGCTCAACGAACGCGGGCGCCAGCCGTGAGAGGAGAAGCTCGGGTTTGTGGAAACT
GGCAATGTTGTCCCCTGAAGCCGGCTCGGGCACCAAGCTGGGTGCGGTGGGGGCCGCGCTAGGTCCGGGTGCG
CACCGAGCGCTTTGGAGAGGGTCAGGTTCAGCACCGCGAACAGCGGTAGCCTCCGCCTCTCTCCTTCCCTGGC
AGACACGGTTCCCTCCTCCTTCTCCTCACCCCCCTCCTTCTCTTCACCCCCCTCTACCCCCTGCTGTCTGGAG
ATGGGCAGTGACCGCCCCTCCCCCCTCCCCACCCCTCCTTGCACTGCCCCCGCCCGCCCGCGTGCATGCGCGA
CTGAGCAGAGGGGCGGCCGATCCCCGAAGTCCGGGCTTCAGGACCCGGGCCGGCAGCACCGGCTGCGAGGGTT
GCCGAAGGCGCACGGATCTGGGCGCTGAAAAAGCCAGGATTTGGCAATGGCTTTGCTGTGTGGCCTTGGGCAA
GTCACTCTGCGTATCTGGGTTTCACTTCCTTCCCAATCCGAAAACGGGATTGGGTTCCTTGCAGCCCGGGCAT
TCCTGAGGTCTCCTTTACCCCTTCTCCTCCCCCAAGCCCCGGGGGCTGTTGTTAACGGCGCCAACATGGGTCT
GAGTAACAAAAGACGCCTGTCCAGGGGGTGAATGAGTTTGGACTCCCCACTGCCAAGTATCCCCCGCGCGCCC
AACTCGGAGCGCCCTGCTGGGCGGGCCCGAGCCTCGGCGGCGGCGCTGAAAATGGCTCATCTGCTCTCTGCTT
TCTCTATTTCGCAGGAGCGGCGGCATGGAGGCTCTCACCACTCAGCTGGGGCCGGGGCGCGAGGGCAGTTCCT
CGCCCAACTCCAAGCAGGAGCTGCAGCCGTACTCGGGCTCCAGCGCTCTCAAACCCAACCAGGTGGGCGAGAC
GTCGCTGTACGGGGTGCCCATTGTGTCGCTGGTCATCGACGGCCAGGAGCGCCTATGCCTGGCGCAGATCTCC
AACACCCTCCTCAAGAACTACAGCTATAATGAGATCCACAACCGCCGCGTGGCCCTGGGCATCACGTGCGTGC
AGTGCACGCCGGTACAGCTGGAGATTCTGCGTCGGGCCGGGGCCATGCCCATCTCGTCGCGCCGCTGCGGCAT
GATCACTAAGCGAGAGGCCGAACGCCTGTGCAAGTCGTTCCTGGGCGAGCACAAACCACCCAAGCTGCCCGAG
AACTTCGCCTTCGATGTGGTGCACGAGTGCGCGTGGGGCTCGCGTGGTAGCTTCATCCCTGCGCGTTACAACA
GCTCTCGTGCCAAGTGCATCAAGTGCGGCTACTGCAGCATGTACTTCTCGCCCAACAAGTTCATCTTCCACTC
GCACCGAACACCCGACGCCAAGTACACGCAGCCCGATGCCGCCAACTTCAACTCCTGGCGTCGTCACCTCAAA
CTCAGTGACAAGTCGGCCACAGACGAACTGAGCCATGCTTGGGAGGACGTCAAGGCCATGTTTAATGGCGGCA
CGCGCAAGCGGACCTTCTCCCTACAAGGAGGCGGCGGAGGCGGTGCCAATGGCGGGTCGGGTGGGCAGGGGAA
GGGTGGTGCTGGCGGCGGTGGCGGCGGTGGCCCAGGGTGCGGTGCAGAGATGGCCCCAGGCCCGCCGCCCCAC
AAAAGCCTGCGCTGTGGCGAAGATGAGGCTGCCGGGCCTCCGGGGCCACCTCCACCCCACCCGCAGCGCGGAC
TTGGCCTGGCGACTGGAGCTAGTGGCCCGGCGGGCCCAGGAGGGCCCGGTGGCGGCGCCGGCGTACGAAGCTA
CCCGGTGATCCCGGTGCCCAGCAAAGGCTTTGGGCTCCTGCAAAAGCTGCCCCCACCACTTTTCCCCCATCCT
TACGGCTTCCCTACGGCCTTCGGCCTATGCCCCAAAAAGGACGACCCGGTTTTAGGCGCGGGCGAGCCAAAGG
GCGGTCCTGGCACTGGGAGCGGCGGCGGCGGCGCGGGGACAGGCGGGGGTGCGGGGGGCCCGGGAGCCAGCCA
CTTGCCCCCGGGGGCAGGGGCGGGCCCGGGCGGCGGCGCCATGTTCTGGGGGCATCAACCCTCCGGGGCAGCC
AAGGACGCAGCGGCAGTGGCTGCAGCGGCCGCCGCCGCCACTGTGTACCCGACGTTTCCCATGTTCTGGCCAG
CAGCAGGCAGCCTCCCGGTACCGTCCTACCCCGCTGCTCAGAGCCAAGCCAAGGCCGTGGCGGCAGCCGTGGC
GGCGGCAGCGGCGGCGGCAGCGGCAGCTGCTGGCAGCGGTGCCCCAGAGCCCCTGGACGGTGCCGAGCCAGCC
AAAGAGAGTGGCCTCGGCGCGGAGGAGCGCTGCCCGAGCGCTCTGTCCCGCGGGCCCCTGGACGAAGACGGCA
CGGACGAGGCGCTGCCACCGCCCCTGGCCCCGTTGCCCCCGCCGCCCCCGCCGCCCGCACGCAAAGGCTCCTA
CGTGTCGGCCTTCCGGCCGGTGGTCAAGGACACCGAGAGCATCGCTAAGCTCTACGGGAGCGCCCGGGAGGCG
TACGGCGCGGGGCCTGCTCGGGGGCCGGGACCCGGCGCTGGGAGCGGCGGCTACGTGAGCCCGGACTTTCTGA
GCGAGGGCAGCTCCAGCTACAATTCCGCCTCGCCCGACGTGGACACCGCGGACGAGCCCGAGGTGGACGTGGA
ATCCAACCGCTTCCCCGACGACGAGGACGCCCAAGAGGAGACCGAGCCCAGCGCACCCAGCGCAGGGGGCGGC
CCAGACGGTGAACAGCCCACTGGACCCCCTTCCGCCACCTCCTCTGGCGCGGACGGTCCCGCAAACTCTCCCG
ACGGCGGCAGCCCCCGCCCCCGGCGCCGCCTCGGGCCACCCCCAGCTGGCCGGCCCGCATTTGGGGACTTGGC
AGCCGAAGACTTGGTGCGGAGACCTGAGAGGAGCCCGCCAAGCGGCGGCGGCGGCTACGAGCTGCGAGAGCCT
TGCGGGCCCCTAGGAGGCCCCGCGCCGGCCAAGGTGAGCCCCGCGCCCGCCCCGCCAGTGGCGCCTTCCCACC
TACCCTGTGCGCGGCAGGGCTGCGGGGCCGGGCGGAGAACGGGAATTTTGTTCCGCGCAGGCGTGGGAGCAGC
AGGCCTCGGCCACTCTCCGCAGGCCCAGCCTTGGGCGCGCTGCGAAACTGGGCCCACCCGCACCCTCCAGTGA
GGGTTTCGAAGGGAAGGGAAGCTGGGGGCGGCGGGAGGACTGGGGAACTTGTGTGCTTTGTTTTTGTTGATGG
GAATGGGGAGGAGACCGGCTGAGACTGCCAGACACAGAGACAGAAAAGGGGTGTGGAGAAAGAAAGAGGAGGT
AAGAAAGGAACCCAGAGCCAGAGAAAAGCGCTCGCCCGGGTGGGCATCAGAGCCCCAAGGAAGAGGAGAAGAG
AGGACAGTGTGGCCTCTCCCTGAGTCGGGCCCCAGCAGTACCGGGTCCCCGGAATCTCCCACCACCCCAACTC
GCAGTTTTCCGAGTCTCTTCGCACTCCCGCCTTGGGAACCACAGGGTTCGTTGCTGGGAAGCTGTCTCGGGAC
CGCGTGCGGAGCGGGAGGGGGGCTCTCAAGCTGGCAGGGCCGGGGCTTGAGGGGCAGGATGCAGCCAGGCTGG
AGTCGTTGGCCATTTTGAAAGTGAGTGCGCATACCTGTACATTCGGTTCATTAAAACACGAATCATTAACCGG
ATGCGAAAGGCGTCATTTATGCCGCGGACGGGGCACTGGCGGGAGGGAAAATGCCTAAAAGGAGGCGGGTGCA
GAGGGTGGAGGACACTTTGAACGCCCCTCGGCTTGGGAGCCGCTTTGTGTTTAGAGTAATTTTCCCGAGGGCG
CTAACAATTACCCTGAATCTACAAGGGGGCAAGGGTGCGCCGCGTGCGTCACTGTGCCCGCTCAAGTCCAGCG
GGCGCACCAACCTTTGCCACTCCGTCGGCTTTCCCTCTTGGCCGCGGGGTAGGGCTGGGCGTCTTTGGGCCGC
CGCAGGGCGCCACCCTAATCGCCTGTCATTTCTCGGCCGTCGCAGGTGTTCGCGCCCGAGAGGGATGAGCACG
TGAAGAGCGCGGCGGTGGCGCTGGGGCCCGCGGCCTCCTACGTCTGCACCCCCGAGGCCCACGGTAACGCCTG
TCGCGGCCGCTGGCCACTGTAATGGGGGAACCGCAGACAGAGGGCCGGGGTCAAGGAAGGCCTGCGAAGGAAG
ACAAGGAGAGAGACGCAGAGAAAGAGGGAGAGGGAAAGAAAAATAATGAAAACAAGGAAGCTAAGCTAGTACT
CCCAACAACTTCCAATCTTTAGTTACTTAAAAACAACAGTGACAACGCCCTCTCCACCACACGCACACACATG
CTGCAGTACACCCAGACACGGCGTTAAACCCTTAACAAAATCACGCCCGACACGGCCTTCAAATCCTCTCATT
TATTCAGCAAGTGTGTTTGGCCGCGGGGTCCCCTTTGGCTAGGCCGGATCGGGGCGGAGGATGGGGGCACATG
GCCGCGCGCTTGGGTACCCCAGAAGCGCCAGGGTAGCTGAGGCCCATCGCGGGGTGGTGGGGGCCGCCCTGCA
CTTGCGCGCCTTACCAGGTTCCTCACAGAGGAGGGGTTGGGGGCAGCGGAAAATCGGGCAGGTCGAGGCAGCC
GAACCCCGGACGATGTCCCCCCACCCACCCCGAAGGTCGCAGCCTGGGCCGCGTTCTCAGCAGGAGTCGGGCG
GACAGACCCGGCGGCCACGCGCGCTCGCGGTGCCCCAGTATCTGCGCGCGATGTAGGTCGCTCGTCCCTGGTG
GGCTCGGCTGCTCGCCTAGCTCTTTTCCAAGGGGCTGGGGCGGGGGCCTGAAGCCCGGAGATGAGCAGACCAG
GCGCGGGGGTGGGGGGTGCCCGGCCCAAAGCCTCAGGGCGCGCTCCTGGGCGCACAGCCGGGAACCAGAGGCG
GCCACGACGCTTTTAATTAGGGCTGGGGCGCCCCGACCGCGGCAGCTCCGGCAGTATCCGGGTCACGGTTTCT
TTGCCTCTCTTGAAATTCGGTTTGTTGCCTTCAAGAGCCAGATAAGGAAGACAATCACTCGCCCGCCGATGAT
TTGGAAACG
CGI: 216 range = chr15: 72206924-72210097
CGGGAAGTAAAGCCTCGGGACTTTGGTTAAGCGCGCCCCACTGGCGTATCGCGCCGCGGGACTGCAGAGCCGT
GAGCAGCGGTCGCCTTGGTGCAGGGTTCCAGCCACATCTTCCTCGCCCAGCCAGCACCCTCTGCCGTTGACCC
GCCTCTGCGCCCGGCAAGCGGCTTCCAGCAGGGGGCGCGCGCGGACCAGGCTTGGGCCCTAGAACAGCGCGGA
TGGAGTCGCTGGAGCAAGTCCCCAGATCCAACCGGTTTCAACCCTCCCCACCCTCCCGACGCTCCGGGTTCGC
GACGTTGAAGTTAAGGGTCGATCCGCAGAAAGCGGCCAGGGGCTCCAGCTCTCCATTCCTGGGTCTGTCTGGG
GTCGGCTCCAGCCTGGTTAGAAGCCTTAGTCTGGATTCGGCAGATTCTGAATCTGGGACCCTCTGCGCTAGCG
GCTTGGAACCTTGTCACCCTCCCCTCCCCCACCCCTACTTCCACACACCTGATTAGTTGTCTGTTTCTTTAAT
GATCAAAGACGTGGGCGGCGGCGGGATGAGGTCTTGGTTCCCGGCTCCACAGCCCTCCCTAACTGTCATTATT
AACGTTATAAACATTAGACCCGCTTCTGCGCGCCGGACGGCGCCGGACGAGGTGCGCGCAGTCTTCTAGCTGA
GCTCGGAGGCAGATCCAGAAGTCGCGGCTCCCACCCCAGGCCTCGGCGGACTCTGCCTGGGGCGACTCGGGCT
CCAGCCCTGCCCGGGCGGGCACTGGGCTCTCCAGGGTCGAAGGCAGGGGTAAGGGGCGTCTTTCCCCCAGGGC
AGCCTCCGGGAACAAAAGCATTTGCTGTAGAGTGAGCTAGAGCCTCCGGGCCCGCGGGAGTCAGCTCCCGCCC
AGGGGTGGTCACCGCGTCCTTAACCACCCCAGGAGCCCCGTCTCCCTGCCGAACTCCTTGGCTTCTGCAACCC
TGTCAAGACAGCAAGGAAAGGGGGTCTTCCCTGGTCCTCGGGCCCCGAAGTTTCGGGGTTGCTTATAGGACGG
GTTCCTGCAGTCCAGGGAAGCTCTGGGCAGATAGCGAGCCCATTCTCCCTTCCATTACCCAGATTCTGCCTCC
CTGCGGAAGGCAAAAAAGAAAGAAAGAAAATAGGTAAAAACCGGCGGAGGGCCTTGAGCCTCCCCGCCTGGCG
CCCCTCACTCAGTCCCGAAAAGTCCCCTGGACACGCCATGCCGGACCGGACTCAGCTCCCGCTGCTGGGCCCC
TGCCTCCAAATATCCTTCCCAGGCACAGGCTCCCAAGACCGCCCCCTCAGGGTTCCCAACACCCGGACAACTG
CCCAAGACGCCGCTCCCCGCCCCCACCCCCACCTTGTTCGGCAGACAAAGAAGGGTGTGCTGGCCCCGCCGTC
TGCCTCCTTCTCCCGACCCCACAAGGCCTAGAAACCTCAGGGACTCACCCCGGGCTAGGGACCCAATCCTGGC
TGTCCCACCACAGGATCCCCGGCAGGGACGGGTCACAGTGCTCTCACCCCTCGACCATTTTCGAAGACACCTT
CCCTGAAAGGCGCCTTGCGCCCTCCCCATGGGTCGGCGGGGGGGGACTCCAGGCCCGAGCAGGCGGTGTGAAG
TTCTGTGTTCTGAACTGGGGCTGAGCAAGATGCGATGGTCTCAGCCCGCTGGGCCGCCCGTAGCGACGGCAGG
AGTAGGGGAGAGGGAGGGACGCTTGGAGTGTGAGCGCACCAGTCTGTTCATATTTAATTTACAAAGCAGCCTC
GGAACCCCGGGCCGGGTGGTCTCTTTAGACGCTGCGCTCTTAGCCTGTCTCTCTTCCCCACCCCCTCCCCTAG
CTCATTAAGATGCTCAACACTCAAATCGGGGTATTGATCTCCACGGAAGCCCCAAACCCTCGCCATCGAGAGA
CCCCCATGGCCCGGGGTGATGGCTGTGGGGCTTGGTGCTCCCAGAGAGCTCAGTGGCTACAGAATGGGTGGGG
ATTCTGCGTGTCTCCCGGAGCCTGAACCCCTTTCCTGGTTATGGCCGGTAGCTGTCTCCAGGGCTAACGTGGG
CAGCGCAGGGGGGCGGAAACCGGGTTTTAGCCAAATGCCTCGACATCGCCGCGCCTCCGCCTCCTCGTCGCTG
AAAGAAATGTCGGGGTTTCATCAGAGCTAGGGAGCGACAGTCGGGAACAGCGAGTCTGCCGAAGCCGGCTGTT
GTGTGAGGGTGTGAGACGGCGGGGCGGTGAGGGGCCACCGCGGCTTGGGGGATAGTGCGTGTGGGGTTGACCG
TGTGTCTGCTTGAGAGGCTGTGAAGATATGGGGGGCAGATATGGGAGAAATGCTCGGGCCTGAAGTCCCCAGC
CCACCGTGCTCAAGAGTAGCGGACGTTTTGCCACCATCCTTGTCTGTGCTACTGTCTGCTGCAGCTTCCGTGC
CCCGTTCTCCTGGAGCAGGCAAGACCTGGAGTGAGGTGCTTGGGTGCGCTCGAGAGAGCTTCCCCCTGCTCCA
CCTGTCCCGCGGTGCGCGCAGGCCAACGCGTCGGGCAGTGGGCTTCAAGCGCTGGTTTAGCCACAAAAGACCA
GAAGTAAAGAGTTCCGGCTTAAGAGGCTGGGCAGGGCTGCGGTGGGCTGGGGAGGGGGGTGTCCCTTCCCAGC
ACGCCCTGCAGGGCTGTGCGTTCTGGTGTCGGGTTAGACTAGCAGGCGGGGCGGGGGGGTTGGGGCGGCGGGG
CGGGGGAGACTAGGGCTTATATCAGCCCAGATCCAGGCAAAAATGGTAGGGAGGGTGCGGCGCTCTGCTAACA
CTATCAATTATGCATCATGTTGAACGTGGCTTCGGGGAGGAGGCGGCTAGCAGCGGGGGGTGCGGGAGGGAAG
GGTCCGCGCGAGCTCGGCTGCGCGCAGCTCAGCGGGTCCCGCTCGAAGTCTGTCGGTGCCACCGCCTGCATTT
GCAAAAAGAGTTTAAAGGCAAAGACACGCCTTCCCCCCCCACTTCAGCCGCGCGCCTTTCCTTCCCCCAAATT
CCTCAAAGATGGTTTGTCTCACGTGTTGCAGGGCGTAAAAGCGGCTTGCATTCAATTAGCAGCGAAGCTCGCG
GGCGCTGGCGGGACAGGCGCGTGAGGGTGAGTTCGCGTGAATGTGTGTATGCGTGTGCGAGAGGAGAACGGTA
AGTGTCCCGGGTGCAGGTGTGCCCGTGAAAATGCG
CGI: 32 range = chr15: 74414579-74414893
CGGAGCTCAAAAGCCGGACGCTACTGGACGAGGCTTAAAGCGCTCGCCCCAGCGCGGGGCCGGTGAGGAACGT
TCACCGTGGACCATGGTCGAATAATGTTAGCGTGCACTCGGGGCCTCGCCCTAGCCTTCTGCAAAGCCTCGGC
CTGCGCCCTCGGCTGCATCCGTTTCGACGCCAACCAACCTCATGCTCTTAGTAGAACGGCAGTAGCGACCGCG
CCCTCAGGCCCACAAGCCCGAAGGTCTGGGCAGGGTCTGGAATGGCGGTGGAGACACTTTATCCGCAGGCGTT
TCACCTCGCGCCCCACCCAGGCG
CGI: 109 range = chr15: 88158407-88159577
CGGCATCTTGGCCGGGTTGTAGGAGCGAGGGAGAACGCGACTGTAACGCGGGCGTTGAGCACCTAGAGTTCCC
CTTCCTCTTCACTGAGAGCTGCGGCGGAGGCTTTAGACCGAGGAGCGAGATCTAAGGTTAAAGAAAGGGCCTC
TGAGCCCAGTGTTGGCCAGAGACCCCACAGGCGGGCCGGGTTCGCCCTTTGCCTTCGGCCGCGCCCCACCCAC
CAGGGACAGAGTGGCCGCGGCCGAGCCGGGTCCACCCGCCGCAGCTTAGCTCCGCTCCGCCGCCCTCCCCGTC
CGTCCTCCCCAGGCTCCCGTCGCCCTCGCCCACCCTGGGGCCCCCTCCCCAGATGGGAGCCCCTCCGACCCCT
GCGAGGCCCGCTGGGGACCCACTTGACCGCGAGATCGTAGTGGGAGCTCGGCCAAAAGAATTCTTCGCTTTCC
CTGGCCCTCAGTTTACCCATCTGGGAAGAGGGGCGTCGCGGCCGCAGAAGTCCAGCTCCGCACGCGCCAAGCG
CTGGGTCTGCAGCTCCCTCGGTTCCCGCGCACCCAACTGCCCCACGACCCCTACCCGCGCCCGCAGCCCCCGC
CCTCCCGCCCCACTTGCCTGGGCCGCCGGGCGCTGGAACCTGGACCCTGGACCCTGGCGGGTTCCGAGCTGCG
CCGCCGCCGTCCCTGCCCCTCCAGCACTGGACTCCTCCTTTCCCGTCTTTTTAAAGGGAAGTAACCGGACCCG
ACCACTACTCCACCCGATTCACCCCTAGCGGGCCGCCCGCCCGCAGCTCCGCCCGGGCTCCTCCCCCGTCCGC
CCGCGGCTTCCCGGGAGCCCCCCAGGGCTCCTCCGCTCCTCCGACGGCCCGGCCTTCCCCCCGGGGCCTGGGA
TGCACCAGGGCTCCTGCTGCCCCCGACGGGGTCCCTGTCGCCGCAGCCCGCGGGACCCGCCGGCCACATCTGG
ACGGCATCTGCCGCGGGGGAGGGGCTCAGAGCCTCGCCCTGAGTGTCCCGCAGGGAGCCTTGTGCATCCGGGG
CAGGAAGCCAGCGCATCCCGTGCAGACGGGTGGTGCAGATAACGGACCCGCCACAGCACGCAATTCAACTTTC
TTGGTACCTGGGACTCGTAGTTCAGAAGGCGCAGTAGCACGACCTTGCGAAAAAGCACCGGAGTCGGGAACAC
GCG
CGI: 21 range = chr16: 727072-727328
CGCCACCCGCACGACGGACGTCGGCACCACACGAGCTGCCCTTGGCAAAACGCGTTGTCGGCTGCTGGGATGG
ATTTCAGGTTAAAGCAGAGTCACCAGGCCGACCACTGCTTACCTTGTTAGCATCTAGAACCTTCTTCAGCTCC
TCGTGGCTCTGCTGGGTGATAAGCACGGTCTCTGCGGAGGTGATGCAGCCGCTGCACGCCAGGCAGTCGTTTA
GCGAGACCTTGGCCTTCTCCAGCCTCCGGGTCCCGCCG
CGI: 61 range = chr16: 47868915-47869809
CGGGTCCACTCCTCACTCGCGAAGTCCCTATCTATCTCTGTGGGTCCCGGAGGCACAGGGCTGCAAGGGCGCC
CGCTAGAGCTGCTCCACGGCTTACCGGATTGCATGCGGAGAAGAAACGGGCCCGGGTTTCAACAGAGGCCCCG
TGCTCCGTGAATTTCTAACTCGAACCAGCCGCTGGGATAAATCCGAGAAACGTTGTTTATTGTGCTATTATTA
ACTTTCCCTTCTCCCCACGCCCCTAGAGGAAATAAAATTCATTCCTGAATATTGGGCCAGGAAAACGTTTCTC
TGAAAGGAACCACAACTGCAGGGGACCACCCGGCTGCAGCTCCCAGCTCCCGGCCCTTCGCCCTAGGCTGCCC
ACTCGCTCCGGCTCCCGACCTCCCCGCTGCCGAAGCAACTGGGTCAGCCTTTCAGACTTAAAACGAAGTCGTT
TATTTCATTTTTGCTTTCACATTATGTTCCGATACAATCAAAACTCCTGGACGAACCTCTTGAATAAAGTCCT
GTGAATGAGCGGAATCATAGGTCCTGGGCGCCCGAGTATGCGGCGGGTGGACTCCGGATTCAGAGGCGGTGTA
TAAAACATACGCTGCTTCGGGAACTGCGAGGGGGACGCGGTGGGAGACATCCGGGGACAGAAGGCCTGAGGAG
TCTGCCGCTCCAGGCAGGGTCGTTTGGGTCCTCAAACTGGGACTATTCCTGATGCATTTGGAATGCAAAGAAA
AAAATCAAACTTCGCTCCTGGGCCGGCGGCCGCGCCTGGCCTAGCAAGATTTCGGCCACATTTCTTACGTTTC
CGCCAAAGCTGTGAACACAGGCGAATGCAGTGCTGGTCCCCGGCCTGGCGCAGGAAGGAGCGCAAGGCCGGCT
TTGCAAGGAAGCCCTCGCG
CGI: 179 range = chr16: 53527803-53530347
CGCGAAGGCTCGGGGCTGCGAGCCGAATGCCCGCCGAGCTGCCTGGGAACGGGAACCGCGCACCCGGGAACGC
CAGGCGTTTCTCTTCATCCAGGAACGGCGCGGAGAGCCTCCGGCTGGGGAGCTAAACCGCTGGGGACTCCGCG
GCTGCTGCCTGAGTCGCTGTCCGCTGCCCGCATCCCTTCCGCCCTGGGCCTCTGCACGGTCTGCGGTTTTCTG
TGCGCACTTGGTCTTCAGTACTAGCACCCAATTACGTCTGGGTTTTTCTTCTTTACAGAGCTGGGTTTCGGTG
GCCACCAGCTTTTCTGGTGTTTAGTGACTCTGAGTTTGGAGGTGGCCTACCAGGCAAACGGGGATTCAGGGCA
TTTAGGAAACGTCTTCCGCGCTTAATCCCAGAAGTGGTTGCGTGTCCGTACGATCCCAAGTTCCTCCCGGAGC
CTCTTCTTTGCTGCGTCTCGGGCCCTCCAGCAGGCGAAGCCTCTTAGACGCGCTGGGGAAACTTCCGGCGTGT
TCGGGGCTCAGGGTTTCTTCTCAGGCATGGATTGGGGCGCAGAAGTTGCGCGAGGCAGCGCCTAAGGTCCCGA
GGTGCTGAGACTGTGCTGGCGTTTGCCACCTGCCCCTGGCTAGGCCGTTTCTGGGCCCCAAGAAACGCCTACC
TTGGCACTTAGGGACCAGAAGCCTCTGGATGTCTAGCAACAGGGGTCACGGGATCACTGCGTGGGGTCTCTGT
AAGCAGTCCCCTGAGGCAGTGCAAAACCGGAAACCTGCTCTGTGCGGGGCCGAATCAGTTCATGGGATTTGGG
AGTCAGGAGAGACGTCTTTCTCCTCCCAGCTCCTACACTCCGGGTACCAAGGCCCGAAATGCCGTTCCCCCAG
CCCGGGTGCGGGGTCTGCAGCAAGGCCTCCTGATTTGCAAACCCCTCCGGGCTGCTTATTCCTGGTGCCATGC
GCAGCCCTTGGGACCTAGAAGATTGTGGGGGAGGGAAGGTCGCACGTGCGGTTTTGGCACCGACCGTGCCTCC
TAGTCCACCTGTCCCCCACAGCTAGCTGCCAACTCGGACGGAAGCGCGGAACAGCGCAATGCAAACCGCCCAA
AGTGAAAGGAATGTAATTGCGCTCCCATGACAGAGCCAGACGCGGATGCAGTTTAGGAAGGGCGCCGCCTACC
GGCCCCTGGGAGCCATGCGATTCGAAGGGAGGGGGACCTAGAGGAGACCCCCGCTATCCCCCCACCCACCGTG
GGGCCTTAGCTTTGAACTCCGGCCCGGACAAACTTAAACTGCTTCGCCACCCCAACGCGCCACAGCCCTGGAC
CTAAGACCCAGTTAGCATTGGGAATTTGGGGAGCAGGGCCCACGACTAGAACAAAGTTAACCCTACCGGTTCC
CGCCACGGCTTCGGCACATTTCAAAAAACCAGGCGCAGGCAATTGAGAAATACGCTGCCGGCTGAAACAGCCT
GCGGGTGGGGGCTGCAGCCGTGCGCGCCCGGCAGTTCCCGTCCCGCATCAGGTGTACGCACTTCCACTCCTGC
GGGCCCTTCCACGCTCCAACTCTGGACCCCGCGCAGTTTTAATCTGCGGTTTGGGAAATGGGGGTGCTACCGT
GCAACCGCGCCCTGAAAGACCGTTTTGGTCTTAAGAGCTTTTGGCCTGTGGGGTGGACATCTGTAGAAAAAGG
AAAAACAAAACAAAAGTAACCTCCCATTGCGTCGAACCCTCCTATTCCGAAAAGAACTTTAATGAGGTTGGCT
TGGCAAGGCCTGCGGTGCTTACCTCGGCTTCGCCCTACCCCGCCAGAAGCCCTCATAGGTTGTATCCACTGGT
CTCCCCCAGGTGCAGGGTTATTAGGGGAAAGGGGGGCGCGCCCTCGGGCTGGATCTTTGTTTCCCTCGTCGCC
CGGTCATCAAACAGGAGGGAAATCGGGCCCGACTGGGACCTTGCTGCCCGCCTTCCCCTTAAACTGGCTAAAG
CTTCAGGACTGTCCCTAGACCCACCCCGCGGGTCTTCCTTTGTGTCCAGGGCATAGCCGATCTCCTTTTCGTT
TTCACGAGAACTGCGACTTGGGCCTCGGGCACTAGGCGAGCCCAGGTTGTGGCCTAACAGCAGATCGCCTCGG
GAGCTTGGCTGCAGCTCTGCCCGCACCTCCAGCGCTGGGCGGCCTCTCGGGGCCAGTGGGGATCTCTGGCCTC
GTGTAGGCCACGGGCCCCAGCCCTGGGTCCCCAAGGCCGCTCGCCGGGCAGCGCTCGTTTCCGGCACCGGGAC
GAGCCCAGCGCGCTCAGACACCACTTTCCCGGTGAAATCTGCTTTTATTTGCTCCGAGCAAACCTCGGGCTCT
CAGCGCTCCCGCCTGATGGATGCAAATGTAAATGTGCACTTATTTAATTGGATCAGGCCCCAAGATAAAAGAG
ATAAACGGCTCCCCGCTTGCTAACTTATTTTCCTAGGCATGCAGCGCCGCGTGGAGGGGAAGCTAATGAAGGA
GCAGCGCGGTGCTGGGCACTCGAGCTCTCCGCAGCCGTGGCACGCTGGCCGGCCGGCCCCGCG
CGI: 78 range = chr16: 66071900-66072846
CGCAGGCCAACGCGAAGACACGATGATCCCAAAGACCTTAGTGTCTTGGCGGGGGGAGGGGGAAGAGGTGGGG
GACTTTTCCGCTTAGCTTCCCTAAGGGTTGCTACGCGACAGCTCTCGGGCTACGTCAGGGTAAAGAGGTTTGT
ATGGCCACACCTCGCACCGACCAACTACCCCCGAAACACCCCCTCCTCCCAAACTGCAGGGTGAGCACAGCGA
GAGAAAAGGTGGCCCAAGCAGAGGCGAACAACTGCGGTTCTTAAAGCCTTGTTTGAGTTTGGGCCCGCGCCGA
GCCACAGCTAGAGGTAGATCCCGCTCCTGCGCGTCCGCTATCAGCCCCAGGATTCCCAGAGAGGCCTCTCAGG
CCCTTCAAGACCCCCCCTTCCGGCTTCCCGGCCTACACCTCTGAACCCTCAGGCCCCGGACAGCCTCTATCCC
CGCCTTTCGCGGCCCCGGCTCACCCTCTAGCGTCTCGCACTGCACCAGGTTGAGGTAGTCGGCCTGGCTGAGC
ACCCCGGCCTTCAGGCCGCGCACCAGTCCCTCCAAGTAGCCATTGTCCACGTTAAAGTAAAGCTCCGGGAAGA
ACGACATGGCTGCTGCGGGAGCGGCGGGACCGGAGAACCAGGACCGGCCGGCACGAATCGCGACTCCCCAGGT
CAGCTGACGCTGCGTCCTCAGCGGGCTGTCAAGTGCGTCAGGTGACGCGCAAGCGCCTCACGTGACCATAAGG
GGGCGTGGCTCTGAGCGGTGCCCGGCTTCCGGGTGGCTGCGCGGAAGCGCGGTGCAGGCGTGGGCTGGCCCTG
CGGCGCCTGCGCGCTAAAAAGAGGAAGTTTGAGGCCGGCCGCTTGGTGGCGCCTGTGGCCGCAGGGATTTGAC
TGGGCCTTCTCTAGCTTTCCCCGGTTTGCTGCACTTGACGCTGCAGGGCGGGCGGGGTAAAGAAGGGAGCG
CGI: 39 range = chr17: 38089258-38089793
CGGGGGTTGGGGGCACGGAAGGGGAAGCTTCGGTCGCTAAGTGGGCCGGCCTTTGGAAGGGTCTGGGAGGGGC
CAGCGCTGACTAACAGTCGGTTTCCCTACCCTAGACGGCTGCGACGAGGAGCTGGTGGGTCCCCTGTATGCAC
GCTCCCTGGGCGCCTCCTCCTACTACAGTCTCCTTACTGCGCCGAGATTCGCCAGGCTGCACGGTGAGCTCCG
CGGAACATCAGCTGCCAACTGGCAGCGCACCGCGGAAGGGTGGGGGCCTCCGGAGGACTTCGGGGAGAGGGAT
AGCCGGTTAAAGCTCCTGTCCTTTCTATAGGCATAAGCGGGTGGTCACCACGGATTGGGGATCCGAATCCCTG
GCTCCAGATAGACTTAATGAAGAAGCACCGGATCCGGGCCGTGGCCACACAGGGCTCCTTTAATTCTTGGGAC
TGGGTCACACGTTACATGCTACTCTACGGCGACCGAGTGGACAGCTGGACACCGTTCTACCAGCGAGGGCACA
ACTCGGTACTCTGGGCGCCAAGGCG
CGI: 69 range = chr17: 44074360-44075233
CGGCGCTGGCGCAGGCGGCCAGGAGAGAGCAGATGAACCGTTCGTTAGGAGCAGCGAGGTAGTCGTGAGCGCT
GAGATCCAGAGACTAGGACCCACTCCCTCTCTGAGCAGCAAATTGGGAAGAAGATGCTCACTCGGTAAGGGCG
AGGGAGCCCGGCATGGCGCCCCACCACGGGCTCGGTCTATCTGCGCGCCAAGATCCCGCTTGGGGCGAGGCGT
TGGGTCAGCGTTTAGAGCCACTCCCTGCGCTGGTGGCTGGACATAGCCTCCCTATCCCACCTCATCTTCCCCC
ATCCCCGACAGAGGAGGTTGTGAATCTACAGGCCCTTGACGTTGAGGCGTCGGAGGGCGCACCTTTGTAATTG
CGGCCTCCCTTCGCCCCTTAAGTGCCGCTTCTGGGCGCCTAGGCTGGATATGAAAGCCCCGTTCCTAATCCTC
TGCTCTGGTCCCCTCCTCTGGACTGCTGGGACTCTAAGCTAGGCCCTCCCCAGGTTCCATCACTGCGGCGCCA
ACCCGCGGCTGGGCTGTCCGCAAGAGGGAGTTGAAGGCGCGCGGAATCCCGAGGTGCAGCTGACCCTCCTCTC
AACGCCGACTCTGCCGCTCCCGCCCGGCCACCTCCCTGTCGGGCAGACTTCCTGTTCTCCTGCTCACAGCAGG
GAGGCAGTCGCCGAGCCGGTCAGCAGCGTGCACGGAGATCTTCACTCTGCGCCCAGCCCCGGGACACAGGTGC
AGATCTCCAGCGGAGCACTGCGGAGTGCGCGCCGTCGAGCACTAGGGAATCCTAGACGGAGGACTTGGTCCAT
TCCACGCAGTCCCAGGCAGGTCCGCAGCGGAGGGACGCAGCGGTCTCCAACTCCTGGTCACGACTTCGGCG
CGI: 269 range = chr17: 67627870-67631593
CGACTCGGCTGACGTTTTTGACCCGGCCAGGAGGCAAAGACCAAAACGTCAGAGCAGTAGCCCTGTTACTGAG
GAGCGTCGGCAGGGTCGCGGGTAGAGGGGGCTGGAGAATGACTTGTCAGAGCTCAAGGTCGATGTGGCGCGGG
GCGGCCTCGAGAGCGCCGGGCTCCTGCGTGGCCACGGCCGCCGCTGCCAACCTTCGCGGGGACTTAGCTTTGC
TTTCCATTGACTCCCTTTGCAAAAGCGCAGCAGAATCCTGACCAGCCGCACCAGCCCCGGCGAACCCGAGCAT
GTTAATCTATTTATATGGATTATTACGGAGGAACAGCGGGCGTTGAGTCACCAAAACATTTGCTTCAAAAGAC
TATTTCTAAGCACTTTTGCAGGCAGGCAGGCTCGCTCCAGGCGCGTAAACTCGGCTACGCATTAAGAAGCGGC
TGCTTTTCGAATACTGCAAACTCCAGCTAAGTCCCCGGTGCCGCGGAGAGAGCAGTGAAAAGAAATGTCGGAG
GTGGGGGTAGATCCTAGTCTAGACACACACACTTGCGCGCACACACACACACACACACACAAGATTCGCGCGG
AGAAGGCACTAAAATTCTGGCATTCCGAGAGTACGACAAACTTACACACTTGGAAGTCCCGGGTCCCCCGCCT
TCCCCGCAGCACCCCCCGCCCCCCCACCCTACCGTCCGCCCTTTGGCTGCGATCCCCTCCCCTCTCCTCCCCT
CCCGCCTCGTCACCCAGCCCAGTGCCACAATCCTCCTCCCTCCCCAAAATCGGGTCCAATCAGCTGCCTGCCA
ACCCTGGGACTGCTGTGCTGTGATTGGCGGGTGGCTCTAAGGTGAGGCGGAGTATTTATTAAAGAGACCCTGG
GCTGGGAGTTGGAGAGCCGAAAGCGGAGCTCGAAACTGACTGGAAACTTCAGTGGCGCGGAGACTCGCCAGTT
TCAACCCCGGAAACTTTTCTTTGCAGGAGGAGAAGAGAAGGGGTGCAAGCGCCCCCACTTTTGCTCTTTTTCC
TCCCCTCCTCCTCCTCTCCAATTCGCCTCCCCCCACTTGGAGCGGGCAGCTGTGAACTGGCCACCCCGCGCCT
TCCTAAGTGCTCGCCGCGGTAGCCGGCCGACGCGCCAGCTTCCCCGGGAGCCGCTTGCTCCGCATCCGGGCAG
CCGAGGGGAGAGGAGCCCGCGCCTCGAGTCCCCGAGCCGCCGCGGCTTCTCGCCTTTCCCGGCCACCAGCCCC
CTGCCCCGGGCCCGCGTATGAATCTCCTGGACCCCTTCATGAAGATGACCGACGAGCAGGAGAAGGGCCTGTC
CGGCGCCCCCAGCCCCACCATGTCCGAGGACTCCGCGGGCTCGCCCTGCCCGTCGGGCTCCGGCTCGGACACC
GAGAACACGCGGCCCCAGGAGAACACGTTCCCCAAGGGCGAGCCCGATCTGAAGAAGGAGAGCGAGGAGGACA
AGTTCCCCGTGTGCATCCGCGAGGCGGTCAGCCAGGTGCTCAAAGGCTACGACTGGACGCTGGTGCCCATGCC
GGTGCGCGTCAACGGCTCCAGCAAGAACAAGCCGCACGTCAAGCGGCCCATGAACGCCTTCATGGTGTGGGCG
CAGGCGGCGCGCAGGAAGCTCGCGGACCAGTACCCGCACTTGCACAACGCCGAGCTCAGCAAGACGCTGGGCA
AGCTCTGGAGGTAGGACCCGGCGGGGGCGGCGCGGCAGGGTGGGCATCGCGGCGGCTGGGGGCGCTGGTCAGG
GCTGATTTGCCCCGCCCCGCCTCCCATCGCCCGGGAGTTGCCGTTCCGGGAGCCGGCGGGATGGGGTTGGGAG
TGGGAATGGGGTGTAACTGTGGCTCAGAGTTTGACAAAGTTCTTGGGCTGCTCGCGGGGACGCGGAGGAGGGG
GGTGGTAAGTGGAAGAGGTGAGGGAGGTAGCTGGAGGATGGACGAAGACTGGTGGGAGACGGAAGGAGGGGGC
TGCCAGCCTGCTCTCCAGTCGCCTGGAAGCTCAATCGGGGCGGGGAAGTGAAACTTGCCTCCCTCCTACCCGG
CCTCTTAAAACTGCACTCTCTCGTGCAGCCCCACTGTCCACGGAGATGGGGCAAGGGAGAAACCGAGGTTGGA
GGAGACCCTTGGCAGGAACTGGGAGGCGGGAGGAGGGAGGCTACTGGAAATAGGTGGGAGTGTATGGTGGGGG
GTGAGAATTGGGGACCTTCTTGCAGCTTAAGTAATTTGGGGGAAAGTTTTCAAAGGGGGTTGGGGTTGGGGGC
GGTAAGTCGAGCAGCAAAGGCGTTTAGGGGGCAGCACCGGGAGTCGTTTTCATCTCCAGCGTTTCCAAAATAG
AAATAGAAGGGGAGGGGAGGGAGGGGGCGGGGAGTGACCGCTCAGGTCAGACTGCAATAACTTATTTATTTAT
TTATTTTTAAGAAAAGTTATGAGCTGTGGTTGCAGGCAGGAGGGAAGATGGAGTTGTGTGCAGAGGAAGCCGA
GTGGTCTGGGTCGCCGCCTCCTCCCCGCCGACCTGACAGTTTGGCGGATTTCACTGACCCCTCTCCCTCTTTT
TCTCTGTGCCCCCCGCCCCGCCCCGAGCAGACTTCTGAACGAGAGCGAGAAGCGGCCCTTCGTGGAGGAGGCG
GAGCGGCTGCGCGTGCAGCACAAGAAGGACCACCCGGATTACAAGTACCAGCCGCGGCGGAGGAAGTCGGTGA
AGAACGGGCAGGCGGAGGCAGAGGAGGCCACGGAGCAGACGCACATCTCCCCCAACGCCATCTTCAAGGCGCT
GCAGGCCGACTCGCCACACTCCTCCTCCGGCATGAGCGAGGTGCACTCCCCCGGCGAGCACTCGGGTGAGTCG
CCCCTCGACCCCACCGGACAAGCTATCTCCGTCCCGCCTGGCACACCCCCTGCCCTCCGCCTGGGAGATTCTT
CGTGGGGACTTTATGCTTCCCGGGAGGGACACACTGCCCTTTGCGCCCGTCCCGCTCCCCTCTCTACCCAGAG
CCTAAGAGGCATCCAAACAACACACACACAAACACACACACCCCAACTCAATCCCAGCATCCGAAGAGATTAA
CTTTTTTATTGGGAGGTAAAATGCCCTTAACAGCCTTACAAGACCTCTCCCTTCTTCTCTGCTCCCCCACCCC
AAAAGCACACACAGGGCTCTTACACAAGTAGCAATTAGGTCTTCCGGACCCTCCGGGCCCCAGACCCTCCCCT
GATAAAAGGGGGCTGTCCAGTGTGTACCGGCGGGTTAATCATTGGGCGACTTATCTCCGGTGCAGCGCGCCTC
TTGCGCGGGTGCGGGCCCTTATTACACTTTAGCAGCGAGGGAGGGTCCCCGGAGGGTGCCTAAGACTAGGGCG
TCTGCACAGCCCTTGTTGATTTTCTCGTGCTTGTTCTTTTATTGTCCACAGGGCAATCCCAGGGCCCACCGAC
CCCACCCACCACCCCCAAAACCGACGTGCAGCCGGGCAAGGCTGACCTGAAGCGAGAGGGGCGCCCCTTGCCA
GAGGGGGGCAGACAGCCCCCTATCGACTTCCGCGACGTGGACATCGGCGAGCTGAGCAGCGACGTCATCTCCA
ACATCGAGACCTTCGATGTCAACGAGTTTGACCAGTACCTGCCGCCCAACGGCCACCCGGGGGTGCCGGCCAC
GCACGGCCAGGTCACCTACACGGGCAGCTACGGCATCAGCAGCACCGCGGCCACCCCGGCGAGCGCGGGCCAC
G
CGI: 260 range = chr17: 71582000-71585125
CGCCTCCGCCCCGCGTTTCCTCCCCCCGATCTCCCAGGGGTCCTCTTTTGAGGGCACCCCAGCCCCTCGACGG
TCCCGGGATATCCTGCACCCCTGCCAGGCTGCAGGGAAGCGCCGAGGCGCGCGGAGTGCGAGGTCCGTGCTCC
CTGCGGCGCGGCGCACACGCAGGGTCCGGGGTCGACCCCTCCACCGCTCCGGCGTCTGCCGGGGAAGTCAGTC
CGCCTGGTCAGCCCAGAACCCCCGACTGCGGGGGCTGGAGCTCGGAAGCAGGTACAAGCGCCACTCTCCGCCT
GCGCCGTGGAATGCGCGCCGGGACCACTCCGCAGCCCTTCCCCCAGCGCCGCCGGCCGCTGCTGGGGACAACC
TCGCCCTCCTGTCTCTTGCTCCTCCTCCTGACCCCAGCGCACCCCCATCCCCGCCCCAGATGAGGCAAGGCTC
CCTCCGCCTTCAGCCCGGCAGAGTCGCACTAGGAGTTGCAGCGGCCGCAGCCCCGGGAGCTTCCCGCTCGCGG
AGACCCAGACGGCTGCAGGAGCCCGGGCAGCCTCGGGGTCAGCGGCACCATGAACGTCTCGGGCTGCCCAGGG
GCCGGGAACGCGAGCCAGGCGGGCGGCGGGGGAGGCTGGCACCCCGAGGCGGTCATCGTGCCCCTGCTCTTCG
CGCTCATCTTCCTCGTGGGCACCGTGGGCAACACGCTGGTGCTGGCGGTGCTGCTGCGCGGCGGCCAGGCGGT
CAGCACTACCAACCTGTTCATCCTTAACCTGGGCGTGGCCGACCTGTGTTTCATCCTGTGCTGCGTGCCCTTC
CAGGCCACCATCTACACCCTGGACGGCTGGGTGTTCGGCTCGCTGCTGTGCAAGGCGGTGCACTTCCTCATCT
TCCTCACCATGCACGCCAGCAGCTTCACGCTGGCCGCCGTCTCCCTGGACAGGTGAGCCAGCGCCTTGGCCTC
CCTGGGAGATGGGCATCCACGCGGGGGATGGAGCGGGAGGCGGGACTGGGGACCAAGAAGGGACGCGCAGAGT
GGGACAGGACACTAAGAAGGCAGTGGAAGACAAGCGGGCGCGGAGGAGGAAAAAGAGGAATAAGAATGGGGGA
CCGTGGTGTCCCTCGGTTAGATGCGTCCTGGGGCCTGGAAGCCTGGAGAATGTGGCTCTCCAGCGCCGCCCGT
GCCTGACAACGCGCAGCGTTTCCCAGTACGACGCGTTTGTGCGCGTTCATCTCGCTTGAGCTTAATGCCCTCC
GTGAGGGTGGGATAGGACAAAGTGCCCAATATACAGAAGAGTTGAGTTCCTAAGTAACTCGCTCAGAGTCGCC
AGCCAGGGATCGGGTGCGTGAAGTGACCGTCTGTCTCCTGCAGCCAACTTCAGGCGCCTCCACTGCGCTCGCC
TCCAAGCCACGGTTTGGTTGGTTGGTGCAGCTGGCTCAGGTCCAGGCTGTGGATCTTGGGTCCTTTGCAAGGA
TCCACTCCGGAGTCCCAGCGAGCGTGCCTAAAGGTCCCTAGCTCAGTCCCAGCCCACTCTGCCTCTCGCCTCC
AAACAAAACAAAACAAAATAAAATCCAAAACAAGTCGGGGCCGGGAGAGGAGCGTGCCCTGGGGTTCTTCCTC
CCCAGCCAGAGGAGAGCGAGAGACGCACATTCGGGAGAGCGCGGGACTCAGGTGGAGCTTGAAAGGACACTGG
GATGGTTCCTGGGGAGGAAATCCGGGTATTTCCCCTCTCCATCCTCTGGAAAAACAGAGAGGCGAGGCCAGAC
TGCCCCCACACCTCCTGTAGCCACTGAGCGCGAAGTGCGTTGGTTCCGAGCGCGCTGGTGGGATCCACAAAGC
TCGCATTCTCTCAGGAATCCCCTGAGAAATTAACTGTCCCTTGCCCAACATGTCTTCTCCAGGCTGTCTGCTA
GAGCCTCAGGCGCCTCCGCCCTCCCTCCCGCGGCACCGTCACCAGTGGGTAGTCACAGCCTCCCGGAGCCCAT
AGCCGGTTCTCCAACCTTTAGTCTTCAGTGGCTTTGGGGTGCCCTCTCAGTGGAGACTGTGGTTGCAGTCCCC
GGGGGCAGCGGGAGAATGGCTTGAAGGCACACCTTTCCTGCTGCCGGGCCCGCCCCATTTCCAGGCTCCGCTG
AGTGTCTGGGACACGCTGGGAGGCCCCCACCTCCGCCCTCACGCCGAGCCTCACCCCCACCTCCTCTGTGTGC
GGTGTAACCATGCGCTAAGGACCTTCCTCGAGAGCAGCCTTGGGACCGAGGTGCAGGGGTCGCGGCCCTCCAG
CATGAATGTGCCCGCTCAGCCGACGTCTCCCTTCCCGGTCTGACCGCAGGTATCTGGCCATCCGCTACCCGCT
GCACTCCCGCGAGCTGCGCACGCCTCGAAACGCGCTGGCAGCCATCGGGCTCATCTGGGGGCTGTCGCTGCTC
TTCTCCGGGCCCTACCTGAGCTACTACCGCCAGTCGCAGCTGGCCAACCTGACCGTGTGCCATCCCGCGTGGA
GCGCCCCTCGCCGCCGCGCCATGGACATCTGCACCTTCGTCTTCAGCTACCTGCTTCCTGTGCTGGTTCTCGG
CCTGACCTACGCGCGCACCTTGCGCTACCTCTGGCGCGCCGTCGACCCGGTGGCCGCGGGCTCGGGTGCCCGG
CGCGCCAAGCGCAAGGTGACACGCATGATCCTCATCGTGGCCGCGCTCTTCTGCCTCTGCTGGATGCCCCACC
ACGCGCTCATCCTCTGCGTGTGGTTCGGCCAGTTCCCGCTCACGCGCGCCACTTATGCGCTTCGCATCCTCTC
GCACCTGGTCTCCTACGCCAACTCCTGCGTCAACCCCATCGTTTACGCGCTGGTCTCCAAGCACTTCCGCAAA
GGCTTCCGCACGATCTGCGCGGGCCTGCTGGGCCGTGCCCCAGGCCGAGCCTCGGGCCGTGTGTGCGCTGCCG
CGCGGGGCACCCACAGTGGCAGCGTGTTGGAGCGCGAGTCCAGCGACCTGTTGCACATGAGCGAGGCGGCGGG
GGCCCTTCGTCCCTGCCCCGGCGCTTCCCAGCCATGCATCCTCGAGCCCTGTCCTGGCCCGTCCTGGCAGGGC
CCAAAGGCAGGCGACAGCATCCTGACGGTTGATGTGGCCTGAAAGCACTTAGCGGGCGCG
CGI: 38 range = chr17: 75936057-75936582
CGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTCTG
GGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGT
ACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAA
ATGGCAGAAGAGCATCGTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTC
CAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGC
TGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGGAGGCCAA
ATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCA
GCGGAGTGGCTGTCG
CGI: 22 range = chr17: 76404186-76404427
CGTCACGTGCAGAGCATCCTCCCGACTGGCGAGGTGGCTTCCACGTGCCCCGTCAATCAGGGCTGGACAGTCC
GTCACGTGCAGAGCATCCTCCCGACTGGCGAGGTGGCTTCCACGTGCCCCGTCAATCAGGGCTGGACAGTCCA
TCACGTGCAGAGCATCCTCCCGACTGGCGAGGTGGCTTCCACGGAGCGATTCTCGAGACCCGAGGGGCGTGGA
CACAGCTTCTACGCAGGCAGTCG
CGI: 53 range = chr17: 77537903-77538626
CGCGCGTCGGGCGCTGGGAAGGTGACTGTGCGTTGGGCGCGCTTGGTGGCCCCAGGGCTGGGCCTGCTCCCGT
CTGACAGTAGTGCCGCGCTGCATGGCACGGGTGTTGCGTTCGTGGGTGAGAGCGCTGAGGTCTGCACGTCGGG
TCTCAGTGGTCATGGGGATGGAAGCCACCCCAGTGGCTGTCGGGGTGAATGGAGGCCCCTGGAGATGGCAGCG
GGTTAAGCACGAGCACGGAATTCTCCCTCCCAAAACGGAACTCAGACAACAGTGACGGAGCCTAAGAGCAAAG
CCAAAGCCACGGGCAGGGGTGAGCGGGACCCGAGGCAGGAGATGACGGAGCCTAAGAGCAAAGCGAAGCCACG
GGCAGGGGTGAGCGGGACCCGAGGCAGGAGGTGACAGAGCCTAAGAGCAAAGCGAAGCCACGGGCAGGGGTGA
GCGGGACCCGAGGCAGGAGATGACGGAGCCTGAGAGCAAAGCGAAGCCACGGGCAGGGGTGAGCGGGACCCGA
GCCAGGAGTGGCGCCGGGCAGGGAGGCAGGCAGCCCCAGGCGCTGTGTGGGCACTGGGTGAGAAGCAGGGATC
CCGGCGCCCTGGCTCTGTGCTGCTTCCTGAGACGAGAGTGGCAGAGGGCAAGAAGAAAACCAAACAGCGCGGG
GAACAGAAGTCAGGAAAGATGAACGTCTGGAAGGAAATGCCCCTGGGCCGGGCGGTGCCCCCGGGCG
CGI: 330 range = chr18: 894579-899574
CGGAGAGACCTCGGAGCAGAGAAGGCGCCGCCGACCCTCGCGGCTGCCTGGCCCGCGGCTCCTACAAAGGCGG
GCTAGCCGCCCGCCCTCTCCCTTGCCTTCCTCCCCTTCTTTTCTGACTTTCCCTCTTTCCCTTAATCGCCTGC
TTCTTCCTCCGGGTGGACTTACGGCCACCTTGCTCCTCCGCGCTTCACCTCATCGCCCCCTCTTTCTTTCTTC
TGCCTCTCTCTCTGCGCCCCCTTCTCTCCGTGTCACGCTCCCTCCTGGTTCTGCGCGTCTACAAACTTTTGAG
CAGAACACGAGCCTCGGCAAACGAGTCCCGCAGCTCCTCCTGCTGCTCCCGCTGGTTCCTGCGGCTTCTGCTC
AGACACCAACGCCAGACGGCGATGCCTCTCGGGTGGTGACTCCAGCGCAGGAACTTGAAGAAGCGCTTTGCCC
GCCGTCCTACCTGGCAGCTCTCCTGGCAGCGGGAGGAGTTGAAGGGTAAGGGAGGGAAAATCTTACCAAAGCG
ACCGGCTCACTCGACTGCTGATTCTTTCGCTTGGCATCGCGTCAGGGGAGTTAGCTTTCCTTCAGCCGGGTCT
GGCTAGTTATTGGGCGCCGGGTAGATGCATATATATATATTTTTTTCTAACTATAGCAAGCAAGAAGTGGCAG
GGCGCGCACCGGCTGTCGCCAAGTGCTGTTCAACTCAGGGAGCCGGGGCTTCGCTCCGTCCCTCCCCCGGCTT
CCAGAGCTTTTTGGGGTTGGAGGGTGGGAGGCCAGGGGCGTTCTCACAGCTGTGTGTCCTCTTTCCCATCCTG
CGCAGAATGACCATGTGTAGCGGAGCGAGGCTGGCCCTGCTGGTCTATGGGATAATCATGCACAGCAGCGTCT
ACAGCTCACCTGCCGCCGCCGGACTCCGGTTCCCCGGGATCAGGTAGGTGCTGGCTGCCTGGCCCAAGCAGGA
GCTGGGGCTTCCCAGGCACAGACGCTTCCTCACGGTCTCCTTCCTGCAGTCCTTTGGGTCCAGACTACTAGCA
TCGCCCTCTGCGCCCCCGGTGCGCCTCCGCCAGCCTCGGCTGGACAGCGGGTCCCCATTCTAGCCGAGGGTCT
GGCAGGCTCCGCGACTGCTCGGACGCCTCCCCCAGCCCTAGGCAGCTCAGGGTCCCGGGTAGAGCCAGTGAGC
TTCTGGCCGCTGGAGAACCCCCCCTCCCCCAACCCGGCCCACAGGATGGGGGCAGGGCACGGCCCCTAGCTTG
GTTTCTTTTACCTATTCTTGGGACGAGTTAGGAGAACTTCAGCTCTGGAGCCTGGCCGGGGGTTGAGCGTGAA
GCTCCCTCGGACTTTGCTTTGTTACTGCTTGTTCTGGACTATCCGGGTGGGGTCTCTCTCTCTCCTCCACCCT
TTCTTTTCATTTCATTCCAATTCTTTCCCCTGAAGAGCTTTCTTTCAAGTGATCCGTGTTCCAACTGCATTTT
GAATCCCAGGCTGTCTTGGGGGGCGTGCGGTGGGGAGGGTGTTGGCCCGGTGTGATTGAGGAAAAGCGACTTA
AGAGAGGGAAGAACAAGGACGAGACTGCGAAGGAGGGGGAAAAACAGGCGCAAAGGAGGAGGAAGGGAAAGCC
AGCAGGCAGGCAGGACCGGGAGAGCAGCCCTGCCTGGCCCGGGATGGAGGAACCTTGGCTTTTTTCTTAACCC
CGGGTTTCTAACCGGCAGGCGCGGCCCAGGTTCCCGGAGGCAGCCCCAGAGTCGCGGACCGATGTGCCAGGCT
GTGGATGAGCCCTGGGTAGGGGAGGGTTCGTACCAGCGGCGCCTGGGGCAGCGAGGAGCGCGCGTTCTGCCTG
CGAAGCTGCCTTCTCCGAGCCCCGCCCAGGAACATTAGCTCTGGGGGGCCGCTGATCATTGATTTGGACGGAG
AGATGGGTTCTGGGTTCTGTATTAGGATTCCAGCATCTGGGCTCGAGGCAGGGCAATATCCAGAAAGACCCCA
GGGTTCGGGGTACCCGGGCCAGGGCTGAGGCGCATCGCCGAGCAAAGGCTGGGTGCGAGGCGTGCGGAATGAT
GCGCTTGCCTTGCCCGGGCCTCTCCAAGGATGGAGAAAAGGCGAGTGAAGCAGCGAAGTACGACTCCAACCCC
GCCCAGAGAGTGCTACTAGCGCTGGCTGCACGCCAAGTCTCTCCAGGGGTCCAAAGCGAGAGGGATTTGTTTT
AACCCATCTCTACCCGTCCTGTGTCAAGAACGGAGGCTGTAGAGGGCGACTGCGAAGTCGCCAGGCACTCGCT
GGATCTCGGTCCCCCTCCTCGTGCTCTGGGGTTGAGATGGGGCACCGCCATCGATAACAGATCAGCGCGAACT
ATTCGTTTAGTGGCCTTAAAACACCCTGGTTTCACCCTCAGCTATTTTCAAGTTCCCGTGTGCCTGGCACTTT
CTCCGTGCGAGAAGCACCGGAGGGTGCGGACGCGCCACAGTCTGAGCCGCCGCCGAACTGGCTAAGTTTAGGG
GCATTTATTATTCATGTTCCTGCCAGATCCTCGCCTGCCCAAAATAGAAACCGAGGTTCTCCGTGACCTACAT
CTGCTCGGAGAAGGGCTCCCCTGGGCTCGGAGGCTGGGGTGGGGGTGGCTGAGGAGTTGGCCCCCGCACGCCC
CACGCATCCTCTCCTTTGCTTTCTGGGCCTCCCCATTCGGGTCTTCGCGTGGGTCAGCGCCCGGTCTCCCAGG
GCCTTTCTCGTCCCCGCCCGTTGCTGCTTTGGGGAGGCTCGGGAGCCAGGCGGGGAGGGGGGCGGTCCTTTTC
CGTAGACAGGTGTGCGCGATCGGCGGAGACGCCTCGGTTTCCCAGCGCTTGTTGAGGCCGTGGCCCGCAGGAC
GACCCTTTACCCGCGAAGGGGGGGTGGGCGGGCCGCCCGGCGGGGTAGGAGTGGTTGGGTGTCGTTGCCTCCT
CCTTACCTCTGCTCCCACCCCCAGTCCTGGGAGAAGAGACAATTCTCAGCGGAGGACTTTTATCACCTGTGAA
AATCCGCGCGAGCCCCTTACTTTGGATCCTCGCCGAGCTGGGGAGGAACTTGCACTGACCACACCTTCTGTCC
CCGGCCACCCCGCAGGCCAGAGGAAGAGGCGTACGGCGAGGACGGAAACCCGCTGCCAGACTTCGATGGCTCG
GAGCCGCCGGGCGCAGGGAGCCCCGCCTCCGCGCCGCGCGCCGCCGCCGCCTGGTACCGCCCGGCCGGGAGAA
GGTGAGATTCGCGCGGCCTCGCGCACACCCGCGGCTGGGAGCTCGGGACTGCGGTGACGGGAGGGGCAGTGTG
GTGACCCACCCAGGATTTTTTTTTTTTTCCCGTGAAAGTCCTCAAGCCTGTCCTCTCCCTGGCCCGATCCTAT
TGCAGCGACAGAAAATCAGCAGCGGGCGGGTCTGTGTGGACCTGAGGGCCGCGTGGGGACCGAGGGGGGCTGT
GGCCCAAAGAGTGGCAGTGAGTGGCGTCAAGGAACCCACACTCCGCATCTGCCACTCCTAGAGCCGGGACTAG
CTCCCGATCCTAGCAGTTGCTCTCGAGATCATCCCGGGAGTTATTGGCGAGTTCTGGGCCTCTGGAGGTTTCC
CTGTCAGCCTCCCCGGCCGCCGAGGGGGCGCGCGCCCAACAAGGGGGTCTCTAGCGGCCACCTGGGGACAGAA
ACAGTGACCCTGGGCGCGCACTTTGCCTCCCCGTTAGAGATGTCGCCCACGGGATCCTTAACGAGGCCTACCG
CAAAGTGCTGGACCAGCTGTCCGCCGGGAAGCACCTGCAGTCGCTCGTGGCCCGGGGCGTGGGGTAAGAGTTT
GTGGAAGGATTAACCTGCGCGCGCCGGGGTGGGTGCCTGTGCGGGGCGCGCGGGGCGGGCGGCGGTGGGTGCC
CGTGGGGGCCAGGGTGAGTCTGCGCCCCTGGGTCTGGGGTGGGCATCCGCCACGGGTCGCAGTTGGAGATTTT
GAAGTGGCACTTTAAATTTGCCCAGAGAGCTCTGGAAGAGGCAAAAAGGGAACGCGAGCCAGGGAGTTTGATC
CGTTTTGAATGAAAAGAAAGAGAAACCAAACCAAACCTCTCAGTCATCCAAAACCTTCAGGCTTCCAGGGAGG
TTTTGCTATAATTTTCTCTAAGCATGACTGTTTCTGGGGGAGGGGAAAGGGGTGGTTGTATTTACTGAAAATT
CAAATCGAAATAATAAATGGCCAAATGTGGACACTTATGGACCCAAACAGTTTTGCTCACGCCAGAGAAACTG
AGAGCACAGGGCTTGTGTGAAGCCTATCTCGGCAGAAGGCAACATTCTAATAAAGCCCGTGGGAAAACAGATT
ACATTTTCGCCATGAATAAGTCATGCAGTGAAAAATATTGCCTACAGCCTGTCGACTTATATTATTATCACGT
TTTTCAACTCGGCGTGAGGAGGGAGAGGAGTGTTCATATTTGACTAGGAATTGCAGGATCGATGCAAACTCCA
GGGCAGCAGCCAGACTGGCATATGTAGGGCTCTCCGGTTACTTTCTCTGTATGTCGCGGGTGAGAGGAACAGC
GAGGACAATTTAGCGCAAACACACGAAGGGTCGGATCTCAAGGGGGCAGCGCTGGGAGAAAGGTTAGGCTTGA
AGCGCGCGTCGCCTGCCCGGATCTTATCCCGGGCCCCCTCCGCAGGGTTTGGTGCCAGGAGATCCTGCGTGGG
GAGGGGGGCATCGAGGGGCTGCCGTCTCGGCCCTCCCCACGGCTGCTTCCAGGCAGAGGCGGGCGACGCGGTG
GGCAGTGCGAGCCCCGGGCCCTCCCCGAAGGCTCCCGCGTGGGGTGGGGCCCGCCTGCTCCCCGCGGCGATTG
AACCTGTGTCTCCCGCCCCGCCACCCTCTTCCCGACCCCTTTGCTTGCAGTGGGAGCCTCGGCGGCGGCGCGG
GGGACGACGCGGAGCCGCTCTCCAAGCGCCACTCGGACGGGATCTTCACGGACAGCTACAGCCGCTACCGGAA
ACAAATGGCTGTCAAGAAATACTTGGCGGCCG
CGI: 338 range = chr18: 74837994-74842232
CGCAGAAATTACTCGTGCGCACCATTTCCGCTGTGGGGGCATTCGTACAAGTTTCCGCTGCACACACAGCCTC
CCGGGCCCTCTCCTCCAAGGCTCTGCCGGATCTTCCAACGAAATCCCAGAGCAGCCTGCGCTGGGGAGCCCGC
AAGTCTCTCCAGATCTCTGCACCCCGCACCGCCCGGAATCTGGGACGGCGCCCACGCAGGGCTGGGCCAAGGG
CAGAGCTCGCACCCTGCCTTCACGCCCGGTTCACTTGCGTCCACGAAAGCAGCGTGCCGGCCTCCTCCATCTT
CCCACTCGCGCAACGCACGGCGACCCGCGCGACACTTCTGCAATCTGAAGGCTTGCTTCTTACAAATAAAGGG
CCAGAGTCTCACACTTGCCTTCGTTGGAGGGACTTAGAAGATCCTCCCCACGTCCACACCTTGTAGGAAATGC
AAAACAGATCGATGAAATTAAACAGTTGCATTTGGAAGCCCCAGAAAGACCTAAAGACATCGTGCCGGTTTGT
TGGAGAGAGGGTTGCGGGACAGGGGGAGCGGGCCTTACGCAACAGAAAAGGTGGGCACAGCGCGCTCAAAATG
ACCCAGTGAGGAGTTGGTGCCGCCGGGCCAGAGGCTGCGAGTCCAGCTGGCTCTGGACTTGCTCCGCAGGCGT
CAGACGCCGTGGGAACCTGTGTCTGCTTCTTCTCTCCAAAGTGTATCGGTTAAAAAAAAATAAAAGTAGTAGT
AGTAGTAGTGGTAAGGAAAAAAATAAAAATAAAAAGGAGACACAATTAACCAGGTCATAAAAGCTAGGGCACC
TTCGACCAGGGCTCTGGCCCTCCAGCGATCGTTTTGCGTTGTTTCTCTTCTCAAAAGTAGTCTCAGACCCCTG
CCTTTCCGCTGCAGCTCTGCGACTTCCCCAAACTCCTTAATCCTGTAAATTCTGCAAGAAACTCCCATCCTGC
AAGCTGCTTTTCCCCCTCCCCCCTGCGTTCCTTTTTTCTCTCCCCACCCGCGCCGCCTCTCTATGCCCCTCTC
TTCTCAGAAAAATTCCTGCCCCCCGCGCGCCCCAAAGCCCGGGCTGCAAACTTTTCCCCGCCGGGCGCCTCTG
CGCCAGATGCCGGAGCGTCTCCACAAAGCCTGAGCATCTGCACAAGTTCGCAGCCTAACTGCGGGATAAAGAC
GTTTCCCCCGTAGCTTAACTAGAAAAGCGCCATCGATGGGTGTGTTAAACGGGATAACTAGAGATTTCAAACA
CCTTTTATTTGCCTGTCTTGAAAAAAAAATCTAAATGAATACGCCCGCTACCAAAAGGCAAAATAAAACCAAC
CTTAAGGGTTTTTGTTGTTTTTTTTTTTTTTCAAAAGTGGCGATAGGGACTGTTTGGACCTGACTCCAACCTG
CGCCCTCCCTTCCTCTATGACCCTCCTGCGCTTTTCCTGGAACCCAAAGCTCTGACTTCGTCAAACTTACACA
ATTAAAGGCAGGCGGAAGAACGCGGGCTGGGAAGCAAGCGGGAAGATTCTAGAATGGAAGGGAGCCCGCCGAG
CGCCGCGAGCCGCGCCAGGCCGGGTCCGATGGAGCAGGCGGGGATTCCTCCCCCAGGCGGACCCCCGCCACCA
GCCCTGCCGGGAGCTCGCGGCCTGCGGAGCGCCCGGGCTGGCCGCTCACCGCCCGCTTCCCCCAGCGAACGAC
TCGGGGAAGCTCCAGGAGGCCATCTGTGCTGACGGTTCACACCAGACAGGACCACTTGCAAGGACAAAAATAA
GAAATTTAGGAAACGAAAAAAGACGTACTGGGGCGAGGGGCGCGGGCGCGGCGACGACGGGGCCGGGGGCACA
TCCTGGCGGCCGCTCGGGGAGAGAGGACACGCGCGGGAAGGAGCGCGGCGGGTGCACGGCCGCGGGTGGGAGT
ACGCGCCTGTGCGCGCGGGGCGAGGGCGAGGGCGCGTGCGTGTGACCGCGGGGAGGGGGCGGGCGCGTGTGCG
GGGAGCGCGCCGCGCCAGGGGCCGAGTGTGTGGGGCCGATCCAGAAGTGCGCAGCCCCCTCACCTGGCCCCCG
TGTCATCCCCGAAATCCCGGGAAAGGGTGGGCCGCGCGCGGGAGTTTGGTGGAGTTGGAACTTTCGGTCGCGC
TCGCTGCCCACTCCGCTGGCGCCCGGTGGCCCGTGGTGAAGGGGGACTAGGGTGGGGAACACCGGGGCCCTGC
GGTCCCCTCCCTTTCCTGTATTTAAGAAGCCGCCGGCGGCGCAGAGGCCCAGGCGGGCTGGCGCGGGGGCGAG
GCGGCCCGGTGGCAGCAGCGGGCGGGGCGGGCGCTCCGGAGTCGGTGGGGCCCGCGGGTTGGGGGGCGGGGAG
AGGGGGGAGTGGAAGGGAGGGGGAACGCAGGGGAGGGAGAGGAGGGGAGGAGCCGCGCGGCCCGCGCCGCTTC
CGAACCGGAAAGTTGGTCTTGCCGAAGTCCTGCCACCCCGGCGTGCGCACTCCGCTCCGCTCCGGCCGCGAGC
CTCCGAGCCCGGCCGGCCGCCGGGGGAAGCCCGCGGAGGGGACGCGGGGCCGGGCGAGAAGGTCCGGAGAGCG
GGGGGCACCTGAGCCCGGGCGGGCCCGCCGCGCTGAGCGGCGCTGAGAGCCGCGGCGGAGCAGCGAAGGCGGC
CGGCCGACCCCGCGCGCCCGGAACAGGAGGCGCGGCGCCCGAGCGGCCCGGGCGAGACAAAGGCGCCGGGTCG
GAGCCCTGCCCGCGGCCGCTCGCTCCGGGAGGGGCCGCCCGGCGGCGGCGGCGGGGGGGGCGCGGGCGGCGGC
GCAGACACTCTATAAAGGGGCGAGCCCGGCGCGCCGGCGGAGACGGCGCCGCGCGGACGCCGCCAAAGTTTGC
TGCCTGCGCCCTGCGGAGGGACGGCCACCGCGGCCCGCGCCGCACCCGGGCCCCGCCACAGCCGCACCCGGGG
CGGCCGAGGAGCGCGGCGCCGGAGCCCGCGATGTGAGGCGGCGCCGGGCAGCGCGCGCCCCGGTCCCGAGGCG
CCGCGGCCCCCTCCTCGTCGGCGCGGCCGCTAATTGCGAGCGCGGCCTCATTTGCATAGGCCGCCGGAGTCCG
CTGGAGCCCGGCCAATCGGCGCGGCCCTCCGCTAATGGCCATGCATTATTCACCAGCCTAATTGCTCAGCCCC
ATGCGCGGCCCGCGCAGCCGCCGCCGCCCCGCGCCCCGCGCCGCGCGCCCGCCAGGCCGCCCCGCGCCGTCCC
CGCCGGCCGCCCCGCTGATGCCGCTGCCCCGCGCGGGGCCCGAGCGCCGCTAGCAGCATGTCTCGGCGCAAGC
AGGCCAAGCCCCAGCACCTCAAGTCGGACGAGGAGCTGCTGCCGCCTGACGGGGCTCCCGAGCACGGTGAGGG
CCGGGGCTGCGGGGTGGCCGGGGGGTCTGGGGCTGCCCGTCCGGGCTGGGGAAGCGCGTGCGGCGGGAGCGGA
TGCGCGCGTCCGGGAGCGGGAGAAAGTTCCCTGCTTCCTGCGGGCAAGCGTCCGCCCCGCGCCAGGCCGGCCG
CGGGGCCCCGGGTACTTCGCCGGAGCGCGCGCGGCCGCCGAGAGAGTTGTGGGCGAAGTAAACTTGGCTCCTC
TCCTCGGAGTCGGGGAGCTGCCCGCGAAGGGCGCCGAGGCCGCGGCCGGCTCGAGGACGGCTCGGAGGCCGGG
GCGGGAGGGAGTCCACGGTGCCTCCGCCGCCGCGCCGCCCCCCAGGGTCTCTGCGCCAGGACGCTGAGGCCGG
CGGCGGCGGGGAAGGCGACCGCAGCCCACCTACCGCTGGACGCGGGTTGGGGACCCCGCCGCCCGGCCAGCTT
TGTTCGGGGGCCCGCGGCCCCTCCCGGGCCCCCGCACCGCCTCGGGTGACCCGCGGTGTCCCAGCGCGTTGAC
GCAGCCTGTGATCCCTCGCGAGGCGAGGAGAAGGTCGGGGGCTTGGCTCTGCCTAATGGCCGCCCGGGGAATT
AAGCTGGGGGTGAGCGCAGCGGCGGCGGCCTGGGCCTGGCCCCTGCTCGCGGCGTGTTTCCGGGGCGTTCGTT
GCAGCGTCTGCGCGGGCCTTTTCTCTCCCGTCTTTTTGGATCCGCCGAGGCCGGGCGCTGGAGACCTCGGCTT
TGCAGTCATTTCGCTGGTAGGAGCGTCCTCTTCGAAACATCCAAGAGCAAAGGGCAGGCGCCGCGAAAGTTAA
GAGACTGGCAAAGGGCTGGACTTCCCAGAGTGGCGCCTTAGCCCCGCAAAGTTTGGGGCGCCCCCACCCCCTT
CGTCG
CGI: 43 range = chr18: 75565313-75565933
CGGGTGCAAACGCATCCTCTGTCCCACGTGGAGTGGTGTGTCCACACGCATGTCCTCTGTCCCATGCCCACGT
GGAGGGGCGTGTACACACGCATGTCCTCTGTCCCGTGTGGAGGGGCGTGTACACGCACACGTGTCCTCTGTCC
CGTGTGGAGGGGCGTGTACATGCTCACATGTGTCCTCTGTCCCGTGTGGAGGGGCGTGTACATGCAAACGTGT
ATCCTCTGTCCCATGTGGAGGGATGGGCACATGTGTGTCTTCAGGACGCCTGTCTCAGGCACCCGTGTGTCTT
CAGGACGCCTGTCGGGCACACGCGTGTCTTCAGAACGCTTGTCTGGGGCACACGTGTGTTCTCAGGATGCCTG
TCTCGGGCACACAGGTTGCGGGGGCGGCCGGGGCTCCTCAGGCCTTTTCTCCCGACTGTTGCTACTATTCTTT
TTAGGGCATCTTTCACTTCCAGCTGGGCCGGGGTGAGCCCATGCTGCACACGCGCCTGCGTCCACACTGCAAG
GACTTCCTGGAGAAGATCGCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTGTACGCACACA
CCATCGCAGGTCAGTCAAGCCGCAGCCGAAGAGGCCG
CGI: 33 range = chr19: 898548-898981
CGGGACCGTTTCACAGATGAGAAGACCGAGGTGCCAGGGTGGCGATCGCACGAAGGGCCCGTCACGGGAGAAT
GAGGAGGGTCTGGCGTCAGCAAGCTCCCCCGGAATCTCGTGATCTGGAAATCCACAGAGAAGCACCTTCACCA
CGCCAGCTTCCCGGGCCGCGCTTCATTGTCATTTCTGGAGAGTGTTATTAATATCCGCCCCGTGGGTGCGGCG
CTGTGTATTTCCAGAGAGGGGACTCGGGGCCCATCAGGGCCGGGGGAGTGGAGCCGGCAGATGTTCGGCCCTG
CCCAGAATCACTTCCCCAATTTCCCCACGCCCGGCGGGGCTCTCAGCATCTGCATCCGCCGAGGCCTGGCTGT
GCTGACGGGAATTGAAAGGACCTCGTGGCTTAGGCAGGCGGGGGAGCCCCCCGGCTGGTCAGGTGCACG
CGI: 70 range = chr19: 9131907-9132918
CGCCGCGACTATGGGGTAGCGTTCAAGGGCAGGCCGCACCTCACTCAGCACATGAGCATGTACGACGGGAGAA
AAATGCATGAATGTCATCAGTGCCAAAAAGCCTTCACCACGAGCGCGTCCCTCACACGGCACAGGAGAATCCA
CACCGGGGAGAAGCCTTACGAGTGCAGCGACTGCGGGAAAGCCTTCAACGACCCTTCAGCCCTTAGGAGCCAC
GCAAGAACTCACCTCAAAGAGAAGCCCTTTGACTGCAGTCAGTGTGGAAATGCATTCCGGACCCTCTCGGCCC
TGAAAATCCACATGCGAGTTCACACTGGCGAGAGGCCTTACAAGTGTGATCAGTGCGGGAAGGCTTACGGCCG
GAGCTGCCACCTCATCGCACACAAGAGAACGCACACCGGAGAGAGGCCCTACGAGTGTCACGACTGTGGGAAA
GCTTTCCAGCACCCCTCCCACCTCAAAGAGCACGTGAGGAATCACACGGGGGAGAAGCCCTACGCGTGCACGC
AGTGCGGCAAAGCCTTCCGCTGGAAGTCCAACTTTAATTTGCACAAGAAGAACCACATGGTGGAGAAGACCTA
CGAATGTAAAGAATGCGGGAAATCCTTTGGCGATCTCGTGTCCCGGAGGAAACACATGAGGATTCACATCGTC
AAGAAACCCGTGGAATGTCGGCAGTGCGGGAAGACCTTCCGAAACCAGTCCATCCTTAAGACTCACATGAACT
CTCACACTGGAGAGAAACCATACGGGTGCGATCTCTGCGGGAAAGCTTTCAGCGCGAGTTCAAACCTCACCGC
ACACAGGAAGATACACACGCAAGAGAGACGCTACGAATGCGCCGCCTGCGGGAAAGTCTTCGGTGACTATTTA
TCCCGGCGGAGGCACATGAGCGTTCACCTTGTAAAGAAACGAGTTGAGTGTAGGCAGTGTGGCAAGGCCTTCA
GGAACCAGTCAACGCTGAAGACGCACATGCGAAGCCACACGGGGGAGAAACCGTACGAATGCG
CGI: 25 range = chr19: 12985960-12986259
CGGAAAGCGCGCTTTTCGGCAGAGCTGGTTAGTTTTTAATGCGGGCTTTTTTTTTCTCACCCGCCGTTCCCTC
CGCTCCGGTCTGATTCGCAAATCCCCAAACTGGCACAAACCGGGAAACTTGCGGCCGGCCGTTCTTCTCCCCG
AGTTGGAGACAGCCCTCTCCTCTTCCCTCCCCCGCCTCTGGGCCCTGACCCACTGCCTGGTTTGCGCTAGAGC
CGTTTAAAAAAGAAAGAAAGGAAGAAAGGAGCCGGGCTCTGGTACCCCGATGCCAGCCGAGGGCGCGTTTCCC
AGGCGGCG
CGI: 35 range = chr19: 55553586-55553895
CGCGACCACCCGCTGCGCATGCGCTTCACTTGGGCGTCACCCGGGGAACTGCGCCTGCGCAGTCTCTCCCCAT
CCGAGGTCCGCTCCGCGAGTGCGAGCGCGCGCCAGGCCCACCCGGGCGCTGCTCTTCATGTCCCCGCGGTCGA
AGACGGCCACATACGTCCCCAAGAAGACGTCACCGAGGATCCAGAAGGGCCCTGCAGGCGGAGGGACATCCAG
GGCCTGGAAACCGGACAAGCAGAGGCGGACGCCATTTCGAGTAGTCTGCAAGGCAACAAGACGACAACTGGGT
GTCGCGGCCACAAGGACG
CGI: 47 range = chr19: 57082654-57083180
CGATTCGCTTCCCCACCACGACGCCCTAGCGCTACTGTGCAACGAAGACCTCCCAAGCACTGGTTCCAATGCG
GAGACCATGGGCTCCCAGACTCTGGGAACTCCAACACGACTGCGAAACGAACTCCGAGCGAGGACTCCCCGAG
AGCTCCCCGCAACACGGACCTCACGCGCTAGCGAACAACAGAAAAAAAAAAGCGCGCTCTCCCTGCCCCTGAA
ACATTCCCAGAAGCCCACGCAGACCAGACCGATGACCTGTCTCCACTGCTGGAGGCGAGTCAGGGACCCGAAG
TCTCTAAACACTCGCCTCTACCCGCCGCCCCGCGAACCCCACACACTGCAGACGCGACACTCGCAAGTTTCGG
GGATGGCGGCCGGCGAGGGCCATACTGCGTCTTTCCGGAGACACGGAATACGGCACCAGCCGTCCCTTTATGA
TGCAATATGTCTGCGCCCAGGGGACGCTTGCTGGGAGCAGCCATTTTCAACCCTACTGCCGTAGAGCAGGCGG
AGTCCCTCTTTTCGCG
CGI: 159 range = chr19: 60283718-60285792
CGAGGTGGGGGCGAGGAACCACCCGGACTGGGTCTCCATGGGCGGGGTCGTGGCTTAGGGCAGGGACAGGTGT
AGGGCGAGGGGTGAGTTCGGGGCGTGGACGTGCGTGGGTTCACAGGTGTGAACGGTAGCCGCACGTGGGCTGG
GACTGAGCTGAAAAATCGGCCAGGGGCGAGGCCCGGGTAGGAAGTGGGTGCGGCGTGGGGAGGCGTGGCCTGA
CGGTGTGATTGGCAGGCGGAGCTGATCCGAGAGGACATCCAGGGGGCTCTGCACAATTACCGCTCGGGCCGCG
GGGAGCGCAGGGCGGCGGCGCTCAGGTGAGAGGGAAGAAGTTGGCAGGGTCTCTGGGAAGCCGGTTTCCCCTC
CTTGTGCCTCAGTCTACAACACCAGCCTGGAACAGAACAAGAGTTTTGCATGGAGTCAAGCACACCCTAGTCG
AGTCTTGTCTGTACCTCCCAGACGAGCTGACCCCTTCTCCAGAACTCTGCTTCTTTTCTCTGTTCCCTGTCCA
GGCCCTCAGTTTCACTCTAGAGAGGTGCTATCCCTCCGTATATCGGATTTCTCCCTACCTCGTTGAACTTGTT
CACTCCCTTTGAGCCTTTTGAGCCTGTGTGTCTCGTTCTGCGCCCTGGATTTCCCCCTCCCTGGACCCCTCAG
TGGACCCAGTCTTGGTGTCCCCGTCGCCCTCCGCAGGGCCACGCAGGAGGAGTTGCAGCGCGACCGCTCGCCC
GCCGCTGAGACCCCGCCCCTGCAGCGCCGCCCGTCAGTCCGCGCAGTGATCAGCACCGTAGAGCGGGGCGCGG
GCCGCGGACGACCCCAGGCGAAGCCCATTCCCGAGGCAGAGGAGGCGCAGAGGCCTGAGCCGGTGGGGACCTC
GAGCAACGCTGACTCGGCCTCCCCGGACCTGGGTCCCCGGGGTCCTGACCTGGCGGTTCTGCAGGCGGAGCGG
GAAGTGGTGAGCCGCTAAGGAAGGGGTCTGGGGGCAGGGCCAGGCGACTGGAGGCGGGGCTAGGGCGTGGAAG
GGCGGGGCCGGCTGCGGGACGGGCGTTCTCTGGTCAGACTTCTGCGTTATGGAAGAGGGGCTGGGTCGGGGGC
GGGGCTTGGTTGTGGGGCGTGGCCAGGTGTTTGGGGCGTGGCCTGATCTGGGGAAGTGTATAGGTGCTCAGGT
TCAGGGCTTCGACGGGGATGGTTTTGGAACTCGGGAGCCCTGAGCGTCCCCCTCCTCTGTCCCCTAGGACATC
CTGAACCACGTGTTCGACGACGTAGAGAGCTTTGTATCGAGGCTGCAGAAGTCGGCGGAGGCGGCCAGGGTGC
TGGAGCACCGGGAACGCGGCCGCAGGAGCCGGCGCCGGGCGGCTGGGGGTAAGGGGCACCCTGGCGTGGGATC
TGAACCCCCTCCCGATCTCTTCCAAATGTCCCCGCTCTCCCCAGGCTCTCCCCTCCCGCCACTTGCCAGGGCT
GACCTCACCGCCATCTTAACCGGGTGTCCACCTCTCTCTGCCTGCCTGGTGCTGGCCCCGCGTCCCCATCGCC
GCGCCCGTCTGCTCCCCTCAGAGGGCTTGCTGACGCTGCGGGCCAAGCCGCCCTCGGAGGCCGAGTACACCGA
CGTGCTGCAGAAGATCAAGTACGCCTTCAGCCTGCTGGTGAGGACGCGCCCGCCCCTGGGCCGGGGCGCGGGC
ACGACGAACCTGTCCCGTCCCCGCACCCACGCCAACCACCTCCCTCCCCACGCCCCAGGCCCGGCTGCGCGGC
AACATCGCCGACCCCTCCTCTCCGGAGCTGTTGCACTTCCTTTTCGGGCCTCTGCAGATGGTGAGACCCGCCC
CAGGCCCTCGGGCCCCCCTGCAGCGGGAGGAATCGGGTTCGACTTGTAGAAGGTGTGGCGGCACAGCCTGCCC
CTCCTGCTCCCCTGACAGATTGTGAACACGTCGGGGGGGCCGGAGTTCGCGAGCAGTGTGCGGCGGCCGCATC
TGACATCGGATGCCGTGGCGCTGCTGCGGGACAACGTCACTCCACGTGAAAACGAGCTCTGGACCTCGCTGGG
GGACTCGTGGACCCGCCCCGGGTGAGGGGCG
CGI: 34 range = chr19: 60907042-60907388
CGCTCCCCTGCGTTTCGGCTGCTGGCCCAGCAGAGGGCGCCGGAGAGCGGACGGAGCCGCAGGCGGGGTTGTG
GGAAGACGCTGGGATCCCGTGCGCGCTTGTGCTCCTTCCTTCTGGGCCAGCGCGCAGACTATCAACCGAGGTA
TTCAGTCCCTCGGAAACCCAGTTCCTCCGTTTCCAGGCTTCTCGCCCACACGGAGACAGTCGCTCTCACACGT
ACCTCTCGCGGGCTCTTACTCGTGGTCCCGGTCTCCTCCTGGTCCCCACCTTCCAGCCCAGCGCGCACACTAG
ACGGCACGTGCTCTCCACGCTCTTTCTCCAGCGCCCCTTGCTCACCCGCCCCCCG
CGI: 61 range = chr19: 62043096-62043807
CGCAGCAAGCCTCAGCCGCCCTTATTTAAGATACCGCCCGAGAGGGCGGGGAAAGAAAACCCCTACAGGCAGG
ACAGCCCTTCGCCCCTCCCACCACCACTGCGGCAAACAAGCCCCGCCCCCAGAGGGTAGCCGGGCACGCCGGC
GCCGCGAGGCCGATGGCACCCCGCAGGAAGGGGCATTTTCGCAGCCCCCAGACCCAGCCCAGGAGGCCCAGGG
CTCCCGAGAGCCGCATTCCGCCGTGGCAACAGGGATAGCATTGGTGTCGACCTTGCTGGACTTGCCGTGGCAG
AGCCCCCGGCTGTCTGCCCTAATGCCCCCGGTTTGCTGCGGTGGCCCCCGGCCAGTCAGAAAGGCGCGGAGAC
CCTGCAGCAGCCCCTCAGACCCCGGACTGCAAGATGGCGGCACCAACGCAGCAGCCCGGGCTGCGCCCACCCC
TGCCCCAAAAAGGCACCAACCATCCACAGCCTGGCCGCCACTGTGCCCACTCTCGGACTGGGCAGCGGGCGGC
CAAGTACCATGTCCGCCAGCCCGCCCTGCCACAAGGGTCGCTGGCTTGCCGCGGGGTCTTGGGCTTGCGGCAA
GACGGCCACTCTGGCCCAGAGCCGTCGCGACACCAAGGTCCCGCGGGCAGGAGGCGCGCGGGGCGGCCGAAGG
CGCACTCACCTCACCTCAGTGCTGCGCAGCCTCGGGCACGAACAGCCGCCTAGCG
CGI: 94 range = chr19: 63321122-63322053
CGCCCAACGAAGAGGAGGGAGTAGGGGTCCGCGCCCCACCACGAAAGGAGAGTAGAGGGCTCGCGCCCTGCGG
GGAGAGGCGTTAGGGGGTCCGCGCCCGGCGAGGAGATGCGCGTACCAGCCCCGCACGCCAAGGGGAGAAGACA
CGCGGGACGGTCCGCGCCTGGCGGAGAGAGTTCCTCACGCCCGCCCCGCCGGGAACCACAAGCCAGCGCCCCT
AACAAGCCCCTGCCCAGAGCAGGGCTGCCGCGTACCCTCACAGACAGAAAGAGCGACCACGCAGCCACCGCCC
AGCCCCAGCCGCTCTGGAGTCCTTGACCCCACCCTCACTAGGCCTTGGCTCCGCGACCGGTGGGCGGGAACGG
AGGAAACAGACCCGAGAGGCCGCGAGAGGACGGAACTCACTTCCCGCCGCCGTAGCGTCCTCGTCAGCTCGCC
CTCCGACTCTCCGCATGGGCGCGCAGAGTTCCCGGATGCGATATTCCGGTGACACCGGACGCTGGGGGCGGGG
CCTAGTGCGACGAGGGCGGGGCCGGGGCCGGCCCGGGGCGGGGCCGTGGCCGCAGCTGCCTGGCAGCCAGAAC
CTGGGAGCGCTCGCAGTGCTGCCTTTCGGGGTTCTTTGTCCTTCGCTTCTGCTGGTAGGTGAGGTTTAACAGA
CGGAAAGACGCCGGGAGCGCACGTGGGCTGCCTTGAGCCGCTGCGGACGAGCACCTTGTCTCTCAGGTTGACC
AGCCGTATATCCGCTTGCGAGCCTGCACCACCCTGGGCGCGCGTGGTCTCGGCAGAATCTCGTTCACACGGGT
CCCACTCGTAGGCTGCTGTGTCTCCTTCCTCTCACGGCGTCGGGGACTGGGGCCTGGAGTCACTCCTCTACAG
GGGTGTGGAACGCGCCAATGGACGCTGACACCTTCATGCGGTCGTTTAACGCTCCG
CGI: 35 range = chr20: 9444472-9444893
CGCTTCCCTATCGGGGCTGCACGTAGAGCATCTAACCGCATGTTCCCGGAACCTGGGATGCGCGCGCGCAAAG
GAGCGCCCAAGCGTGCAACCCAGAGTTTGGACGCGCCGCCCTTTACAGCCCCCGCCCCGGGGCCGGGCGAGCT
GAGGGGGCGCGGGGCGTCTGTGTTCCCAGCTGATCACAGAACAGGCCGATATCGCATTGACCCGGGGAGCTGA
GGTGAAGGGCCGCTGTGGCCACAGCCAGTCGGAGCTGCAAGTGTTCTGGGTGGATCGCGCATATGCACTCAAA
ATGCTCTTTGTAAAGGTAACTCCGAGCCCAGCGGGCAGAGGGGCCGCAGGCTCCGCGTGGGTGTGGGAAGTGG
CGGCCCCTAGGTTTAAGAACCCAGACGCTGCGGGGACGATTGAAGCGCACCTCCCCG
CGI: 671 range = chr20: 21433933-21444714
CGCGGAGACATCTCGAGTCCCGCAGGTGTCTGAGCTGCGCTGCGCGCCCCAGCCGGGAAGCCTTTTCTTATCC
AACCGCGCCGCCCCGCGGAAAGCCTGGGTACTGCAGACGCCCTCACCGGCCCACCGACAGCTGGTTTTGAAGC
GGGGGCTTAGAAAAGTAAAGGGGACAGTGTTTGGAGCCACGATGCCTTTGATGTGAGGCGGTTCCACCCAACA
ATCAACGAATCAAGCTGGAACTGCAGGCCCTACTTTTGTTGGGGGGAGGACCTTAAGGAATGTCACCCCCTTG
TCCCCTACCCTCTGCCCCACGCCCAGCCTCTCAGAAGGCACCAGGCGTGAGTAGAGTGCGAGGCGTCCACACC
CTCGTGTCCCTTCCATTCCCGGACACCTTTGCACCCTAGCCGAGGCCTCAGCACGGAGTGAGGGTTGCCTGGG
GTGCCCTGCTGTGTGTGGGGCGTTCTTGCCTCCCGGGCCCTGACCCCACGGTCTGGGTCGGCGAGGCGTCTCT
CCCTGGCGTCTGGACTGTGCGCCTGCCCCGCTTCCAGGCGACGAACGGCAGGAGCCGGGGGTCCGGCGGGACC
CGGATCCAGGGCGGGCGGAAGGCGAGGGTCTCTCCTTCCCGGAACCCCCGCCCCGGAAACCTGCAACCAAACC
GGGTCCCTCCTCCGCATCGCTCCCGCGCTCCCGGGCCGCCTCCCCACGCGGGCACCCACTCTCCGGGCCCTCG
CAGCACCGCCCTCTCCGCGTCCACCCGCGCGGCCGACGCCGCCAGGGGCCCTGAGATCGCGGAGACAGCGCGC
CCTGGCGCCTGGTGGGGCCCTCCCAGTGGCCAGAGCGCTCCTGGACCAGTCGGCTGTGGTCTGTGCCCAAACA
CGATGGAAACCGGGGCTGGGACGGGCGGTGGTACGCACGTGGAGGAGAAGAGGCATGGCGGGAAAACCACAGC
CGAACACAGGTCGACTCGCACCTCCCAGGCACCCGCCGCCGTCTGACTCGCGGCTCTCCCCAAGGTTCCGACT
CGCCGCCACCTCTTGGCACCACTCACCGGGCTCCGACCCGGGCCGCGAGTCCGCTGATGCGCAGCTGCCTCCG
GCGGCTCCCGGGCTCTGCCCGGACCCGCGCGCAGAGACGCTCGGGAACGCTGGGCTCGGGCGCCTCCTGGCGG
CGGCAGCACGCGGCACACGCTCGGTTCTCCGGCCCGAGGGGGCGCGTGGAGCGTACGCGGGATCCGCGCGCGG
GCCTGGGCTGCTGGCCCACATTTCCCCGCTTGCTCGGATGGCGGCGCTGAGGCCTATTCGCCTCTTTATTAAT
AACGATGCCTCGGGAGGGAAAAAATAGAGCCTTTAAAAATCAGAGTGCGAGAGAGGAGTGTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTGTGTCTCGGGGCGTTGGTGAAAGCAATAAAACTCAGATCGCTTCCTTGGCGAGAT
AGCGGCGGCTATAATGCGCCGGGGGGATCAGGGGTTTATTTGCAGATCCTGGATAAAAGATGATATATCGACA
CGGTTTAGAGTGTCACTGCGCTTGGCCTCTCAGGGAGCCACAAGTACATATTTCCTGAAATACCGCCCAGCAC
AGTATCTAATCCGCCCGCCACTTAACACCGGGAGGGGAACTTCAGCAGCGCACAAGCGCGCTCCCGGTTTCCT
GGTTCTGGGTGGGGAGAGCCCAAATGAGAAGGATCTGGTATGCCTAGACGCCCCCTCCCCTGGCCTTTGTCTT
CAGTCCAAGTAATCACTTAGCGATGGGCCTTAATAAATACGTCTGAGAACTGTCCTTATGCTCGGTAAATATT
GGATTAGCTTTTCAATGACCAGGCTCTTGAAAAGGCTCGAGAAATACACACCAGGTCTCAACTAAGCCCAACA
GTCAATAGGTAAGGAAATAAGTTATTTCCCCATCTGAGGTGGGGAATGTTGGGAAGGGGGACTTCCACTCTTA
CCAAATTATCTGATTCTACTAAATATGACCGTTGTACTAAATAGGAAAGGGGGCGCATCCAAGTTTCCCATTA
GTCGGAATTTCCACCAGCTCAGTTCTGCTCATTAAGGGCCGAGTGACTTTGTGGGGAACATATCTGGGTTCCA
GTTTTTATTTCCACAGAGCTCAGCATAAACTATTTTTGTTTAGTACATATGGTTTATTTGGGGACTGCTTATG
GGAGTTTTGACCTGGCAATTGCAGGGGAGAAGGCATGACCCAAATTATTTCCGACTGCCTCGCGCCAATTTGG
ACCGCTTAGAGGAGGCAAAAAATGGGCAAATTCCTTGGAAGCCCTGCTGTGTCTCCCTGGTACTGAATTTTGT
AAGCACGCGATACAGGAGACATTGAAAATTAAAGAGGAAGTATCTCCCTCCTCCAACATGGGGAGAGACGCTG
TTGGAAGAAGTTTCTGAAGTGGTTTCCCATCGCACCAAGAGGCCAGTGGGATGGATCCCCGCGCATAATTCAA
AGGAACGCGCGCGTCTTTAGCTCTTCGGGGTTGGTAACCAAGTGGTCCGGCCGGGCGCAAGTCGCCTTGGAAC
CGGCTGCAGCCCAAGTCTAGCTGGGCCCGGGACTGAGCGGCACCCTTGGCCTCTCAGAACCTTTCTCGCGGTG
AGTGGAAGGGCGGCTCCGCGCGCGGGCGCTTCGGGGCCGGTCGGTTGCGAAATCAGGGGGTGGATTTTCATCT
ACCCAGGAGCCGCTAAGCCCGTAGGGGACCGAGCATCACCCAGGCCCTGGGTACCCTGAGTTGCCTCCTGAGC
CCCAGGACGGTCCGATGGTGCAGAGCTCCCAGGCAGAAGTTAGTTTCCTGATACACACACAGCAGTGAGCAAA
GTGCGCACAAGTGAGCCAAACCCTGAAGACGCAGGTTCGCGGACTCCCATCCCAGCGTTAGAGTCAAGGAGAC
AGAAGAGAGGAAGGAGAGAAGTGAGGAAGGGAGAGAGATTATGAGAAAAAGAGATTATGAAAGTAGAGAAAGA
GATTATGAGAGCGAGATTATGAGAAGAGAGAAAAAGAGAGATTTTGAGAGAGAGAGACAGAATGAGAGAGATC
CAACTTTCAGTGTCACGGGGCCTAGGCGGGGCAAGCGCCCTCCGAAGCCATCAAAGACAGGGGTGGCTTTTTC
TCCCCTCCTCCAGCCTCCTCCCCAATAGATATAGCACGAATTTTTAATGCGTCTTCCTTTCACAGACAACAAT
ACAGGGTTTGAAAGCCGGACACAATTTAGGTTTTGTGCGGGTCCCTCCTCGCGCTCCCTCGGCCCAGCTGGCC
ATATGGAATCCAGCATGGAGCCCGTGGATGACAAAGGGACCCAGTGACAGGCCCAACAAAACCCCAAGGAGAC
TTCTGCCTGACTCCGGGATTCACTGCCGGCGATAAGCGCGCTGAATGGTGCGGGGTGGGGCGGGGGGTGGGGG
GCGGGCCCCTTCTCCTTCTTCCCCTCTCTCTGTCCCCGCGATCCTTTCTCTGTCCCTTTTTAATATGCACGCC
TCTAACATCTCCGGCTCCCAGCTTTCCCATTGTGCGGTTTTGTACCGCCCGCTGTAGATTGGGCGAAGATAGA
CTGCTGAAGCGGACCCCGCGCCGGGTGCGCTCCCAGGGCGCTGGGGTTAGGGCCACACAGGGCTCCGCAGGCG
CTTTTATTGACTCCATGGGGACCCGAGGACAGAGAGAGGCGGGCGCCGGGTCCACCTCCCGGGCTCCCGGCCG
GCCACAGGAGCGCACACCCAGATTGCAGGCCCGCGGTCCTGGCCACAGCTCCAAATTTGTCCTCAATGAGCAA
GTGGTGGAAGCCTGCCAGGGTGAGGACCTTCCACGCTTCCCCCTTCCTCTCTGGAAACCTGAGGGTCTCTTGT
GATCATTCTCACCCTGGAAGCCCTGGGGCCTGGAAAAGTCAAAATGGCCTCAGGCCTTCTGACAGCTCCGCTC
CAAGAGACTTGAAACCCTCACCTTTCCTCCCAAGAGGATTTTGGGATTAGGGGAAGTTGCAAGTGGATGTTGA
GTGGTTAGTACCAGGGCAGGTTGGGCGTTCAATTATTGCACAACAAACTATTTGGGAGAAATTCGTTGGCCTT
TAAAAACAGTAAGACATAAGCCCCCAAACATTGCCAAGCTAGTGTGGAGAACAAAGGGAGACCTTTTAGCATT
TAGAAAAACTGCCCTTTCCCCGAGGATGAGCCCGGAGATGGGAAAGGACCTTTACTGGGGTATTAGAAAGACT
TCCGAGCCCTCAATTATCCAGGGGCGGTGTGGAACGCGGGAATAAAGTGTCATCGCGTCCCTGGGCTGCTGCG
CAGAGTGCTATCGACGCACAGATTTGGTCGCACGGATAATCATGTTTGCTTTAGATATTGAATTAAACCTGAT
CATCAACTACAGGGAGCGAGAAAGTCAGCTGGGACCGCTCCTTTTGCCCGGCCTCCTCACTGCCACCCAACCC
CCCAGCCTTGATGGTGCAGCTTCGGAGAGAACAGAGATACAATTTCCAAATGCGCCGACGTTCAGTCCCTCAG
CGTCTGCAGCACCCGCTGGGCTCTGAGCTAGAGTCCCAAGTATTTTTAGAAACCCGCGAGATAGAGGAGAAAG
GCTCATCCTCCAGTTGGCCAGGCTTCCTAAGACGCTCCCCCGCGTGGCCAAGTGTGCGCCAGCATCTGCCAAG
GAGATCTTCCTCCAGCAACAAGGGTGGGACGGAATCCGTTCCCCGCCGGAAAGATGGATGCGCCCTTCCCGGG
CGTGCCCGGGGCTGTGTGCCCACTTCCCATCCGGGGAGCTCACCCCACCCCCAAACCTCTACTTCCTAGCAAT
CCACCCAGTTCCACGCTCAAGGGCTGACCTGGGGGGACCGCACACCCTGGTTCGGACCGCCGAACGCTGGAGG
GAAGGAGGCCCGGGATCCAGTCCCCGGAGAGAGGCCTGGAAGCCCGGAAAGGATGGGAGCGTAAGGGAAGGGA
GAGGCATGGTTTGCTGGGATTGCCAAAGATTCTCGCTCCCTGGCTTCCTGGGGCCAAAGATCCTAGGGAGGGC
TGCAGTATCCCCTCCCTCCCCCGAGCCCAGAACCCCGCGTACTTCCCCCAAGCCCCCTAAGCCAAAGCCTCGC
GCGCCCTGACCGTTCCCACCCCCAGCCTTAGCGGTCTCCTAGGTCAGCACCAGCCCGCAGATTTTGAAAAGGA
GTGGGGAGTGGGGAGAAGGCAGCCAGTCTTAACCTCAGACCCCCACCCACCCACTTTCTTAGCGTGAGGTAAG
TCAAATGTAACAAAGTGAAAGTCATCGAGTGTAGTGGCTTCAACAGCTTCTCAGGCTGAAGGAGCCACTCATA
GATTTGGGCCAGCGAGGGGGGTTTGCTCTCCTCGCCTTTGCGGCTCCCGAAGTCACTTTTCCTCCCGTAGCCG
GACGCTGCCGCCCGGGGTTCAGACAGCGCGCGAGACCAGGGGAGATGCGGGGGAGGGTGGGCGGCCCTGGGCT
TCCGGCCGACCGCTCGCAGGCCGGAGGCCGAGCGTTCTCCTCCCCGCCCCAATCCTAGGCGCGGGGTGCAGCC
TGTGGTCGGAGGGGCCTGCACCGGGAGCCCCGCCCGCCCCAGGGCCCCGGTACCCCCGGCCTCCCCGCCCGAG
AGGAACCGCCTGTGGGAGCCCCGCGGGCGGCCGGGCCCGGCTCCCAGGCCCAGGCCTCCGGCCCGGCGCAGTA
GGACAAACGGGAGGGCAGGGATTTTTTCTTTTTTTCTTTTTTAAACACAGGATTTTTATTAAAATTCTTATTT
AAAAAATCGAAAGCTTTCTGCGCCCGGCGCTGTTGGGGAACCGCGCCGAATAGCTGAGCTCCAAGTTCGGGGC
TGAAGGCCCGGAGGACAGGGCAGAGGGCTCCCTGCCTACAGGGTTTTCTTTTCCATATTTGAGAAATGTTTGC
ACAATAAAATAAAAAGAGAAAGGAAGAAAGCAGGGGAAAACGCAAAAACAAAAACAAAACAAAAAACAAACCC
AAACAAGCCACAAAGAAAGGAGTTGGACCCAGACGGGAAACAGGCCGGTCCTGAAGGTCATTTTGGCAACAAT
CACCACCGATATTTACAACGAAAAGCGAAATCTGCCACCAGTTGTCAGAACGTTTACATGGCCATAAATATTT
AGCATTTTCTTATTTTTTTTTAAAAAAAGGAAGAAATTCTCTGTATTTTTAAAGTGTTCTCCACTTGCTTTAG
AAGACGGCTGACAATATCGCTACTCACACAAACATATTTTACAAAATGCACGAAAGCAGGGGTGGGGGGTCGG
TCTTTTTCTCGTTTTCAAGTGACGACATTAACGCTGGGACGGTTTGGTCCCCCCGGGGAGAGGCAAAGAAGCG
AAGCTGCGCAAACATTCTGTAAACACGGCGTAGAGTTCAGCCCTCTCCCAAGGTTCAGAAGGAGAGGCATGGG
CAGAGCTGGGTGGGTGGAATCTGCCACTCCAAGGAGACGCAGGCAACCTCCCGGCGCCTCCCTAGTGGAGCCG
AGAGTCAACTCGACTCCATAATAATAATTATAATAATAATAATAACCACCATAAGGACCGAGGCCTCCTCGCC
GCCACCGCCGCCGGGGTGGGGCCTGGGCCTGGGGCCGCGAGTCTCGTTGGGGCGGCGCTCACCAAGTCCACTG
CTGGGCCTGGACCAGGGGGTGTGCTGTCGGGTACTGGGGGGTGCTGGCCGAGCTGTACTGGGCGTTGTACTGC
ATGTGCTGCAGCGACTGCGCGCTGTAGGCAGAAAAGGGAATGCCCGCCTGGAAGGTGGCGGCTGCCAGGTCCT
GGGCTTTGAGCGCGTGACATGGTTTGCCGTCCCTGACCAAGACGGGCACGGCCACCCGGCGCGGCGAGGGCAG
GGGCGTCACCTCCATACCTTTCTCGGCCCGGGCGCGCTTCATCTTGTAGCGGTGGTTCTGGAACCAGATCTTG
ACCTGCGTGGGCGTGAGGCGGATGAGGCTGGCCAGGTGTTCGCGCTCGGGCGCCGACAGGTACCGCTGCTGCC
GAAAGCGCCGCTCCAGCTCGTAGGTCTGCGCCTTGGAGAAAAGCACTCGCCGCTTTCGCTTCTTGCCGGCGTC
CCCCCCGCCGCCCGGGGTCTCCTTGTCATTGTCCGGTGACTCGTCGGCCGAGGGCTCCGGGGACTTGGAGCTT
GAGTCCTGAGGGGGCGCCCCGGCAGCCAGACCGTGCACTGGGGGGAGGGGGAGAGAGAAGCGCGTCAGGCGTC
TGGAGGCCGCGCGCAGCCTGCACCAGACTCGGAGCACCCTGGATCCTCCGTGCGACCCTGGACCTCCGCGCCT
GGCAGCCCAGCCCCGCTGCCTTTGCCATGACCCCTGCCTTCCTCTACGCCTGACGAAGACGTCGGGACCTCCC
AGGGTAAAGAGGGAAATCCGTAGGAGTGGGGGCTAGGGGCTCGCCTTTCAAGGGGCTCACATAGTGTGGGTGA
GAATTTGGGGGGGGAAGTGGCACTGAAGATCATCGCGGGTTAAGGGCTCCGGCGCCCTTAAGCGGTTTCCTCT
CCGGCGAGACGTGGGCAGATTTTTAAAAGAAATACCCCACAATCCCAGCATTGATCGGCTCGGCCATTTAAGG
CAGGTTTTTGGGGGCTTTCGTTTCTGCTTTCGGGCCTTCTAGACACCCCCTGCACTGCACAAAGCGTCCTCTA
TGATCGCGCAGGGGGCAGGGTGAGCTATTTATACCCGGGCCACCCGAAGCCTCCCCACCCTCCACCCGTACCC
GGACGAGGCTCGCTGGCTACCTCCAGGGCGCCAGGCCAGTCCCTCCCAGCGGCCGGAGTCCGGGGGCTGCGGC
TGGAGCCATCGGTCCGGGTTGACATCATATACCAGCCCCTGGGAGGTATAGCCCTTCTCCCTCTTTCTCCTTA
ACTTCTCGCATTGAAAAAAATTTTGGAGACCAAGTTCTTTCCCGGAACTAAGGAGGCTTGAAGAGGAGGGCAG
AGGACATCCTATACAGGTGTTAAAAATCTTTCTACGGATCCGAGTGAGGGGGTCCGGGCTTACATGGCCCCTT
CCCCTTTCACTCCCAGCGTCCAACCCGGGCTGCGGCTGCAGGAATGGAGGGGACCACGGCCTCGGCAGCCAAG
TTTTGCTACTTACGGGAGTACTGAAGGCCCTCGGTGCTGGCCAGCCAGCGCGTGTACGGGTTGTCGCTGCTGT
CGTAGAAGGGGTTCTTCAGGGGCAGGCTCTGCACCGCGTCCAGGGCGCCCTGCCCCAGCGGCCCGGCCCTCTT
GGCTGGCTCGGGCCCCTCGTTCTCTTCCTCCGGACCTTCGGCCACAGAGCCCTCCTCATCGTTGGTGTCCGGC
AGGTCTAAGATGTCCTTGACCGAAAACCCCGTCTTTGTGTTGGTCAGCGACATGGTTCGAGACCCCAAAATTT
ATGTCGCAAAGTTGTAGCTTCACTTGGTCAATTCGTGGCGCTCCCCTGCCCCGGCGGGCGGGGGAGGGGGGAG
TTGGGGGGAGGGACTGGGGGAGGGGAGGGGGGAATTGGCTTTAATTATTGGGATAATTATTATTTTTAAAAAG
AGAAAGAAACTGGGGATGGGGAGGAAAAAAATGAAGCCCAACCCAGTGCCTCTCTCTGTCTTCTTTGAAAGCA
CGCGGAAATGGACGCAGGAAGCCGGGCGGCCTGCGCGCCGAGCGCCGCGGGCCCCGGCCTTAGTTTCTAACTC
CAGGAGGGGTGCCAAGGCGGCGTCAGCTCGGGCTCCGGCGGCCGCTCGGCGCGCGGTGGCGGCTGGTGGCGAG
GAAAAAATGGGCCATTGCCCGAGCGATCAGTCCATATAAGGCTGGGCTCCACTCACGAACCTGGGGAGGCGGG
GAGAGGGGGAGAAAGAGAGGGAGGGAGGGAAAGAAAGAGGGAGGGAGGGGGAGCGAGAGAGGGAGCGGGAGAA
GGGTGGAAAAAAGGGGGAAGAGACATTAAAAACGCAAAGGTTGGCCACGTGTGGGCGGGTCTTGGGAGTCAAG
TGGATGAAGACAGTATTTGCAGATGTGAAATTGTGGGTTTTGGGGAGCTCCGCGCTCCCAGCCAACGGCCCTC
TAGAGCAAGATGAGAGGTGTAACGTGTCAATTAATTGCAAAGACGGGGCGAGCCTTTTTTTTTTTAAACCCAG
TATTTACATACAAAGGGCCACCGCGTCGCTCGCGAGTCCACACACTTGAAAGGGCCGTTTTAACAAATTGCAT
CTTAAAAAAGGTGGGGGTGGGGAGGAGGAGGGGAGAAAACAAAACAGAAACCAGGAGGAGGGAAAAAATCCTC
TTTAACATTCACCGGTTCCTACCTCCCCGCCCCCGCGCGCCCACCCCCGGCAAGCCGGAAAATTGGCGATTTG
TGGCGCCTTTGGAAAAGGGGGAGGGGGCGAAGGCCGAGCTGCGGAAATCTCTCCTTTCCATCGTTGGTGGTTG
CCTAAACAAGATCCGGTTCAAATGGCAAGAGCCCAACTTCTGTAAGCCTCCTAGGTCAATATTTTGGTTGAGG
CTTAAGGATGAGTGCTAGAAATGACAAGGCAAGTAATTGATTCCAGTTAACCGCGAGAGAGCCCAAAACCCAG
GAGAGAGCTCCGCTCCGGGCCGGCCAGAGCCACCACCAAGCGACCCGCCCCCTTCCAGCCGCCCTTTATTTGC
TAAAGACTCATTTATTTCCTTCACTCCGCCTCCCCCCACCTCCCACCCCCAACCCCCCGCCTCCACCTCTCTG
CGGCCAAGGAGGACGCGCAGTTCACTTTCTGCTTTGCGGGCGGTCCCGGGGAGGGCGGGGTAAGAGTGAGGAG
CTCCAACTTCGTCTGGGGTCGGACCCTGGCCCTGCTGCCTCTGGGCTCTGCGGGCCTCTTTCCCCGGGTGGAG
GAAAGGGCAGACGGCCCTGCTCTTTCCTGCCCTCTATTATCCCTCCCTCTCCGGCCCCCTCCCTCTCCAGCCT
CTGGCTAGAGGTGGAGCAGCGGGAAGGCGGCGGGGCGGGATTGCGGGGGTGGGGGTGGGGGTTGTGTCTCCAG
CCTGGGTGAAGACCCAGAAAGCTGCGGGGGAGGGGGGTCGCTGGGTGGCCCGACGATGCCTCGTTTTCTCCCC
AGTTTTCTTCTCCCACGCGAGTTCTTTAGTGTGGTCTCTTTTTGGACGCCTTGGGTGCGTTCGGAGTACGCGC
TCCACGTTTCCAGGTTAAGTCAGGTTAGTGTGAAGTTTCCAGCCACTCTCGGCTCTGGGAACTGAACTTTCCC
GGGACTTGCACTTCCTCCTCGGCGCTGGGGTTGGAAAAGACCACGCCGCATTTGCCACCCCTTCTTCTAGTTA
AAACTTTTTTGGGGGGGGGGTGCAGGGGTGTAGATTGGCTACCTGATGCTCGTTCGCCCCAGAGGAGTGTCAG
GAAGGAGCTTTGTCTGGGGGCGGGGAGGGGCACAGAAGGCCACCCCTGCGGGGTCCAGGTCTAGTCTTCCCAC
AACCTGGGCTCCTCCGCGCGGGCCAAGCTGAGCGCGCGGGCACCGGGTCCTCCTCGCGCGCAGCTGCAGCGGA
CGCCGCCGCGCCCCAGCTGCCCCCGGGTTGCCAGCGCTGGGTGAGGGCACCTCTCCCCGAGCCGCTCGGCGGC
TTTCTGCAGCCCTAGCTGCCTCGCCCCCAGTATGTGACGTGGGTGACAATGGCCCAGGTTAGAGCAAGCCCCT
CGTCGGCGCGTCCTGGGTGGTCGGACCCGGGCAAACACAAATACAAACCGATTGCTAAGCTGCGGACAATGAG
CGAAATGTAGACAAATGTCCCGCTCCCGTTGGAAGCCTTTGTCCCGGCTCG
CGI: 61 range = chr20: 23294035-23294650
CGCCACGGCGTGGCCACCGAGGTGGTGTACCGCTGCGACACCTGCGGCCAGACCTTCGCCAACCGCTGCAACC
TGAAGAGCCACCAGCGCCACGTGCACAGCAGCGAGCGCCATTTCCCATGCGAGCTGTGCGGGAAGAAGTTCAA
GCGCAAGAAGGACGTGAAGCGGCACGTGCTGCAGGTGCATGAGGGCGGCGGCGAGCGGCACCGCTGCGGCCAG
TGCGGCAAGGGCCTGAGTTCCAAGACAGCGCTGCGGCTGCACGAGCGCACACACACGGGAGACCGGCCCTACG
GCTGCACCGAGTGCGGCGCCAGGTTCTCGCAGCCGTCCGCGCTCAAGACGCACATGAGGTACGCGGGGAGCCG
TCCGGAGGGGTCCCTGCGCACTGGAAGGGTGTGTCAAGCACTGAGGTCGTCCTGGGATTTGATGTCTCACTGC
TTAATTTCTCCGCTCCAAACCTGGGGGCTTATTTCGAGACAGCGTTTAGTTCTCTGTCAAGGTACAGGGGCTG
CGAGTGATGGCTCTGCTCCCTTGTTCTGAGACCCCTGGGGCGCCCCTGCTGGCCGGGACGTCCCTCTGGTGGG
ACCGCGACAGCGGCCGCGGGCTCGCCCCACCG
CGI: 118 range = chr20: 25011839-25013525
CGCGCTTTGAACCCAACCAGCCCTCATCGCTCGGAGCCCTGCGTCCCCCGCTTCCCAATCCCAGAACCCCGGA
AGCAGATCTCCTCAGTCCCACTCCCTGAGGGTCCTACAGTCCGAGGTCCCGCAGCGAGGGAGGAGCAAACGCC
TGAGCTCCGCGGGAACCCGGCGCGGCTGCCTGCGCGCACGCAGGGACCGGAGCCCGAGCCTGGGCCCTGCAAA
GTGGGTCTCCCACTCGCTGCGCGTTCGAGTGGGGCCTCCGCTAAACATGCAGATTAAACAAGGGGCTTCCGAT
AAGGATAATTACAGGAGGCTGCGCATTGACTTTCCGTTACTAAAGGAAGACCCAAATCTCCCCCTTGCAAGCT
GTTCCCGGGATTACCAAAACAATCACTTTCTTTTGAGATCATTGTCTTTTGAACCACTCCAGCTCGGGGCAGA
ACGCTTTAGACGCTGGCGTTGTTTTCCGCTCCGCGAGGAATTTTCCCCCAGATTTATCTCTGGGTTTAGGGAA
GGCGTTGGGCATTCGGGACTGCGTAGTCGTTTGTAAATCCGAATTTGGGGTAGCAGTTAAGTGAGATACCTAC
GCTTCCACACAGTTTGTAGCCCGAGACCAGTCAGGCAGGCAGGGTAGTCGATTCTAAGGTGGCCCGACCGGGG
TCGCCCGCGAATGGAAAGCCTAAGGGGCGAGGGCGGACGCGGGCGCCGTGCCTGCAGCCCCGGGTGCCGACCA
AGTGGCCTCACCTGGGACAGGTCTTGGGGTCTCCCTCCCCTAGGTCTCCCTGGAAGGTAGGCGATCACGGGAG
TGACAGACCCCGAGTAGATAGCCAGTGATCCAAAGACACCAAAAGGCCAGGCGGTAGGAGCCCAGCCTCAGAC
ACTCTCTATAGTGACCGCGGCGCCTCGGGAAGGATCGTCTTAAACTCATTTTGCAGGTGAGAGCAACTGGGAC
TTATTAACCCAGTCACATCGGACACAGAGACGTGGCGAGGGCGACACAGAGCAGGAGACTCAATCAAGGAGCC
CGTATTGGAGCTCTAAGGGGACTCAGAGATGCAGAAGGAACGAACTTCTAAGGGGTCTTGCAATTCCTGGACT
GGGGCGTTCCTAATGCATCCCGGGACCCCAATGCCAGGGAGGGGCCTGCAGGACCCCAGCGGTGGGCGAGTTG
TGTCCTGGGTCACCTTGTGTTTCGCAGCGTGGCGGTGGCAGGAGCCCAGCGCGGGAGGACATTTTCATAGCCT
CCTACAGTGAGAAACGCCCCCCACCCGACGCTGCGCTCATCTGTGTCCCCGCTGTTGCCGGGGCTCTGGTATC
CACTTGCGCGCCCTATGTGGTGGGGATCCACCCAGAGCCCAGCGTCAAGTTATACGGGCGCTTCACTCAGCGT
CAGCCAAGACCAGGGAAGCGCTTCTTGCCGTTTAGGAGACGTCTGCAAGAGATAAAAAGCTAGCCCACGATCC
ACCCACAATCCTCGTGTCCCCGGGGTGCCCTCGCAGTTGCCAAACCTACGGGCCGCGTTTAGGGGAAGCCTCC
GCGTCCTGGCGGCCAAAAGAATGGGCTCCTTCCAGCTTCCCCCTACCGGATACCACCTGCAAATCTATTGCCA
GAGGCGCAGCTCCCGCGAACGTTCCCGCCCCGGGCGGCCCCCAGGAGTCGTTTTGGGTCCCTAAATCCGTTGA
GGGTTCCG
CGI: 380 range = chr20: 36785545-36790786
CGGCCGTCGGAGCAGGGCCCCAGCGCACCGCGAGCCTCTGCTTCCTCCGCCTTGCAGCGCCGCGAGCCCTTCT
TTCCTCCGCGCCTGGCCCCGTCTGCGCCCCTCTCGGCGTGGGCATTCGCAGACCCGCTAGGAGGCTGACGAGA
GGTGTCCTCATAGAGTCCTGCCTTCTTCCAGACCCCCAAACGAAAAGAAAGAGAAAAGCCAACCTTTCGCCTC
CATTCTGCACGCATTTGGAGAGCGGCTGGTGGCGAGCGATCCGCACAATCGCTTCCCTCGCGGCGTCCCTGGA
CGGGCGGAGAGAACCCGGGTGACTGAGCCTGAGGCTGAGCTTCCTTGGGAGCGATCCATGCCAGCCACTTCTA
CCTTCAAGGGGGACTCGCGGCCGGGTTTACGCGCGAAGGATGGGTGCCAGGGAAACTGACTTATAGACGACCC
GCTCCGCGAGAGACTGACAACTCAGTCCTGCGGGCTTTCGGGGCGCCCAGACCAGTCCTTAGCCAGAGGATCT
GGGGCTGCACAGCTCCCGGACCCTGGAGGGGGTGGTCCGGGGGTGGGAGACTGCGAGCATCAGCCCACGCCGG
CCCCCTCCCACCCTGCGGCGGCGAGGTGGGAAGGGCCAGGATGCGAGCTTAGCACCTCCCCTAGAAATGCAGC
ACTTCGCCCCCCCACCTCCCCTGCCCTCGGCGCTCCCTCTTTCACGCGCTCCCTCCCGCCTCCTTCCCAAGGG
CGCCCTTCTTCTGCCCCCAGCTCACGTCTGAATCCCTCGGCGCCCCCTTTCTCTTCTCCTAGCCCCTTCCTCA
CGTCCCCTGCCTCCGGGTATTTCCTCTCTCCAATCCCCCACCCCCGCACCGCCTGATTCCGAGGGGCGGGAGC
GCATTGGGCTGCGCACGGGTGGGGGCGCCGCGCCAGCTTCGCGTAGCTGCTCTGACGCCGCTGCCGCCGCCGC
CGCCGCCGCCGCCCTCCGCAGCCCAGCTCGCGCCCCGCGGCAGCTCCGCAGTGCACTAGCCACCACCGCCGCC
GCCGCCGCTCCGCCAGACCTGCTGCCAGCTTGCCCGGTCCAGCCCTGAGAGAGCCTCGAACGCCAGCTGCGAG
GGTCATGAGCCAGAGAGCCCCGGGGCGCCGCGCGGAGAGCAAGCGGAGATAGCGACTTTGCGCCCCCCAGCCC
TCGCCTTCTTGCATCGCGTTCCCCGCATCCTCGGGTCCTTCTGTCCTTTCCGCTGTCCCCACCGCCGCCATGG
CCACCTTGCTCCGCAGCAAGCTGTCCAACGTGGCCACGTCCGTGTCCAACAAGTCCCAGGCCAAGATGAGCGG
CATGTTCGCCAGGATGGGTTTTCAGGCGGCCACGGATGAGGAGGCGGTGGGCTTCGCGCATTGCGACGACCTC
GACTTTGAGCACCGCCAGGGCCTGCAGATGGACATCCTGAAAGCCGAGGGAGAGCCCTGCGGGGACGAGGGCG
CTGAAGCGCCCGTCGAGGGAGACATCCATTATCAGCGAGGCAGCGGAGCTCCTCTGCCGCCCTCCGGCTCCAA
GGACCAGGTGGGAGGTGGTGGCGAATTCGGGGGCCACGACAAGCCCAAAATCACGGCGTGGGAGGCAGGCTGG
AACGTGACCAACGCCATCCAGGTAAGCGCGGGATTCCCAGTTCTGCCTGTCCTCCCCCCTCCCAGCTCAGCGT
GCCGGGCTCTGCCCCCGACAGTCGCCCGGTGATCTCGGCCTGGAGACCCCCTCCTGTACCCAGGAATCTCCCT
TTCTCCATCCCTCCCAGCCCTGCGCGGGGACCTACGCCCCCAGGCGGTGTTTTCCGCCCTAACCCACGCTCCC
TCCCAACGGCACCAGCTGCAAGACCGCTAGGCTGAAGTTCGGTCTGAGACACCTGTCCGGAGACACTGCAAAA
GTGAAGGAAATGGGGGGAGGGAGCAGGAAGCGATGAGAAAGAAAGAAAATCAGGATTGGAGGGCACGGTTTGG
TCTTGGACTCTGGAACGGATTCACAGCTGCATTTTTGGGAGGAAAGAAGAAGGGGAAATCGCTGAGGTCGGAG
TCTCCTCCCCCCGCACACACGCATAGACACGCACACGTATATAGGCAGGCACACCACATGCCCACAGCCCCCC
TTCCCACGAACAAAGGCGCAGGCACAGGCGCACACGACATGTATCTATATATAGACCACAGTACTATCCCCAA
ATGCACCTGCGTACACCCCTACAGCTCCACAAACAAAAGCATATACCTGCACATACCAAACACACGAATATTC
GTTTGAACATATGCACACACACATGCACAGATGCATGCAGACAGGAACCAGCCTGCTCCCTTGGGTGCGGCCC
TGTTGGAGACATACAGGTATACACACACGAAAGCACACACATGCTCCCACACAAACACATTTAGTCCGCAATA
ATCCAGCATTACCTGTGCACAGACTCGCCCCTCTCGCCCGAAATCCCGGCTGCACCGCAAAGAGGCGGCCAGC
TCCTCCCCGTGTGACCCTGGCGAAGCCCTCTCCAGAGGCTAAGAATGGCCCCTGCTCTCTAGGCCCTCTCCCC
TTATTCCTAACCCCCCACTCCCCACCAGGCGGCGCAGGACTCCTACATAGGGAGCAGGTTTGGAGTCTTGGCA
ACGACCTCCGAGCTAGCAGGGGCTGGCAGGCCGCAGCTTTCTGGGCCGAAGGAGACTTCAGCTCTAGGCAACC
CCGGTCCCTTACAGCTTGGCCCCGCGGCGTCCCTGGAGCGCACTATCACTGGGGCCACGGAAGGCAGGTTTTC
TGGGAGCAGAGGCCTCCCAGGGGTTGTTCCATGTATCGGGGTAAGCAGGACTCCACCGGGCCCCGAACACCAG
ATGGCCCGACCCAAGGCGCTTTCCGCTCCGGGGCCCGGCGAGACGGCCTTGCTGGATCACGGACCCGGGGCTG
CTCCCGCCTTCGCTGTGCCCCGCGACTTCCCGGGGCGTCTTTCAAGGCTCCGTTTGATAGGCCCCAAGGGAGG
CCAGGGCAGGAGGCTGGAGGCTCGTAGGCCTCCGGGACCCTGGATTTCGTTAGCTCTTAGTCCCCGTGTGGAT
TCTAAACCCTACAGCCCTGTCCGCCTGACCCTGAAGCTTCTGGTTCTAGACTCTTGCTCGGTTCGGCTTTCTG
GCCTCCCTGGCGCCTTCCCGCCAAGCTCCTCCTCCTGCTTGCCTCCCCAGCCTCCACTTAGTCCCCTTCCTTA
GGTCTCGCCCTCGCCTCACTCTAACTCCAGCCTTGTCCTAAGACTCTCAATTTCCAGCCCTGCTTCCTCCTCC
CCGCGCGCTGCTCCCCAAGCGTCTTCACATTGTCTCTGTTCTTGCCTCCCAGGGGCTTTGCCCCACCTTCAGC
CCCTCTCCCTCTCTACCCTATTTCCTTTTCGCCTCACAACTGCAGCCTTTAACGTTTCCTCCTCTGGTCTGAG
CCTGAGACGCCCGAGTTTTCCTCTTTAGCTCCCGTGCCCCATTCCAGCCCCACCACAAATCCCGTGCCCACTC
TTTCCACTGGCCCAGGCCCAGCTCACTACCTTTCTTAGAGCCCCTTTCCGACTACGCTCCCTTCTGTCCCTTC
TCATCTCCTCCCCCAACTCCTCATTCTGTTCCTGTCCCCAGAAACCATCCCGAAGTATCTCCCTTCCCTCCTG
TGGCTTCTCCCTATTCTCAGCCCTCTCCCACCCTAGCCCTCTCGCTATCACCAGCCATTAGCGCACCTTTCCT
TCTCAGATCCGTCCATACATCCCTCCCTCTCCATCTCTGGCTCGACACCCGGGCTCACTATTAGTTCCCCTAC
ATCCACCCCGCAGCCTGCTCTTAACCTCTCCTCCCCGGCGGCTCAGACCCAATTCTCAGTGTCCTTAGCGCCC
CCTTCGGGCCACAGCGTTAAGCCACGCCCCCCGGGCCCCTCATCCGTTGCCAAGTTCGCTGAGCGTCCGCGTC
TGGTTGCCTCTCCGCCCCACAGGGCATGTTCGTGCTGGGCCTACCCTACGCCATCCTGCACGGCGGCTACCTG
GGGTTGTTTCTCATCATCTTCGCCGCCGTTGTGTGCTGCTACACCGGCAAGATCCTCATCGCGTGCCTGTACG
AGGAGAATGAAGACGGCGAGGTGGTGCGCGTGCGGGACTCGTACGTGGCCATAGCCAACGCCTGCTGCGCCCC
GCGCTTCCCAACGCTGGGCGGCCGAGTGGTGAACGTAGCGCAGATCATCGAGCTGGTGATGACGTGCATCCTG
TACGTGGTGGTGAGTGGCAACCTCATGTACAACAGCTTCCCGGGGCTGCCCGTGTCGCAGAAGTCCTGGTCCA
TTATCGCCACGGCCGTGCTGCTGCCTTGCGCCTTCCTTAAGAACCTCAAGGCCGTGTCCAAGTTCAGTCTGCT
GTGCACTCTGGCCCACTTCGTCATCAATATCCTGGTCATAGCCTACTGTCTATCGCGGGCGCGCGACTGGGCC
TGGGAGAAGGTCAAGTTCTACATCGACGTCAAGAAGTTCCCCATCTCCATTGGCATCATCGTGTTCAGCTACA
CGTCTCAGATCTTCCTGCCTTCGCTGGAGGGCAATATGCAGCAGCCCAGCGAGTTCCACTGCATGATGAACTG
GACGCACATCGCAGCCTGCGTGCTCAAGGGCCTCTTCGCGCTCGTCGCCTACCTCACCTGGGCCGACGAGACC
AAGGAGGTCATCACGGATAACCTGCCCGGCTCCATCCGCGCCGTGGTCAACATCTTTCTGGTGGCCAAGGCGC
TGTTGTCCTATCCTCTGCCATTCTTTGCCGCTGTCGAGGTGCTGGAGAAGTCGCTCTTCCAGGAAGGCAGCCG
CGCCTTTTTCCCGGCCTGCTACAGCGGCGACGGGCGCCTGAAGTCCTGGGGGCTGACGCTGCGCTGCGCGCTC
GTCGTCTTCACGCTGCTCATGGCCATTTATGTGCCGCACTTCGCGCTGCTCATGGGCCTCACCGGCAGCCTCA
CGGGCGCCGGCCTCTGTTTCTTGCTGCCCAGCCTCTTTCACCTGCGCCTGCTCTGGCGCAAGCTGCTGTGGCA
CCAAGTCTTCTTCGACGTCGCCATCTTCGTCATCGGCGGCATCTGCAGCGTGTCCGGCTTCGTGCACTCCCTC
GAGGGCCTCATCGAAGCCTACCGAACCAACGCGGAGGACTAGGGCGCAAGGGCGAGCCCCCGCCGCGCTTCTG
CGCTCTCTCCCTTCTCCCCTCACCCCGCCCCCACCAGCCCAGTGCGCCCTGCCGCCGCG
CGI: 315 range = chr20: 38749965-38753401
CGCTGGTGGAGCCCGCCTCCCTGAAGCCGGAGTTGGCGAGTTTCTCGCACTTGACCTTGTAGGCGTCTCTCTC
GCGGGCCAGCCGGGACACCTCCTGCTTAAGCTGCTCCACCTGCTGAATGAGCTGCGTCTTCTCATTCTCCAGG
TGGTGCTTCTGCTGGACGCGTTTATACCTGCAAGACTGGGCGTAGCCCCGGTTCTTCAGGGTCCGCCGCTTCT
GCTTCAGGCGGATCACCTCGTCCTTGGTGAAGCCCCGCAGGTGGCGGTTCAGCTCGCGCACGGACATGGACAC
GAGCTGGTCGTCGGAGAAGCGGTCCTCCACGCTGCCGTTGCCGCCCGCCGCCGTCGCCGAGGCCGTCGCGTGC
GGCCCGGGCCCGGGGTGGCTAGTGGGCAGCTGTTGCGCCGGGCTAGCGGCGCTGGACGGCGGCGGCGACGCTT
GGTGATGATGGTGATGGTGCGGGTGAGCGTGCGGGCCCAGCTCGTCGTGGGCCACGCCGGCGCCCGGGTACGC
GTGGTGCGGGTGAGGGTGGTGGTGATGGTGGTGGTGGTGAGCGCCGCGAAAGCTGTCGAAGCTTTGCAGCGGC
TGTGGCACTGGGTGCGAGCCGATGAGCGCTTCCACCGCGTCCTCGGGCGTCAGGTTGAGCGCCTCGGGGTTCA
TCTGCTGGTAGTTGCTCGCCATCCAGTACAGATCCTCGAGGTGTGTCTTCTGTTCGGTCGGGCTGAAGCTGGG
CGACGAGGGCACGGAGCTACACGGAGTGCTGAGCGGTGTGGAGGACACCGAGCCGGCTGGCTGCAGGCGTGTG
CAGGGCCTGCCCGGACGCTCCGCGCGCCCCAGTGGCTCCTTCTTCACGTCGAACTTGAGCAGGTCGAAGTCGT
TGACATACTCCATGGCCAGCGGGCTGGTGGGCAGCTCTGGCCCCATGCTCAGCTCCGCGGCCATCGCTGAAGC
GAGGCGCAGCCGCCGCTGCCGCCCGGGAAACTTTGCGGCCGGCCGGAGCGCGCCGAGCCAAGCGCGGGGGGGA
AGAGCGGAGAAGAGCTGGGGAGGCGGGGAGCGAGGGCGCAGCGGGCCGGGGCCGCCGGCCAAGCCTTTGTCTG
GGGACGCGGCGGCGCGCCGGAGAGTCCCGAGGCTGCCTGCACCGCCCCAGAGCTCTGGGCTGTGCCCGCGCAG
GGACCGGGCCGGGTAGAGTCGGGCGGGGTGGAGAGGCAAGCGGAGCGCGCGGTGGGGCTGAGGGGAGGCGTGG
GGCGAGTGCCCGTTGCTCGCTCTCTAGCTCTCTTGCTCTTACGCTCTCTCGCTCGCAGCCGCTCGCAGCTCGG
CGGTGCAGCTGTGCTGGATCCGGCGGCGCCGCAGCCTTTTATCGCCTCCTGATGTCACTGGGGTGCGGGGGCC
CGGGCGGCCCGGTGCGCGGGCCAATAGCTGCACGGCCTCCGCGGCCCAGCGGCGCAGGGCGGGGCGCGCCTGA
CAGCTCCCCCGCCCCCCGCGTCAGCTGACTGGCGGCCCGAGCGGCCCCGGAGCGGCGGAGGCCTGGCGGAGCG
CTGGAGCGGAGTGGGACGGCCAGCCTGGGCCCACCCCCGTACCCTGCAGGTCCCGGCCCACGCACGCTCGCCT
GGAGTGCGCGCCCCACCTCTAGGCCAAATCACCGCTTTCCCCTCCTCGCGCACTCTCCTCCCTCAGTTCCCTT
TGCACCCCACCCCCATCCCGTGTCACCCCCAAGGAGGCTCAGAATGAGCGCCGGGACAACGCCTCCTGGGCCC
TTTGTTCCCAAGCGGCCCCCGCCCAGTGGGCGACGCTCTGTGTGTCCTCGCGGCTTCTGGCCGTGTGTGTCGT
GCGTTCCTGTTTCTGGAGATCTGCGCGTATTTGTATGTTGGGGAGGGCGGGCTCGAGGCTCCGAGAGTTGTGT
TCAGACCCAACTCTTAACCTCAGGGGACCTTTCTCAGGCCAAGCGAGGGCCCCTCCTGGCGGGTGCAGTCGCA
GAGCCCTGAGGTTCGACTCCACTGGCCCCGCCGCTCCCCGCGTTCACCCCACCGCACAATGTTCACAGTGAAG
GCGACGGGAAAAGCAGCAGCCCAAAGGCTCTGAATTCCTCTTCCCCGCCACACGCACGGAATCCTGAGCCCCC
GGAGCCTCGGGGCCGAGGCCGGCCCGGGACGGTGCTCCGAGTAGCTCTCCACTGCTGGGGAGCCGGCCCTGTT
TTTGTTTGAACGTTTTGTAACGATTAAGCAGATCCCGGCGTCAGCCCGCCGCGGAGAGGCTCAAACAGGCATA
AAGTGCGACCCCAAGTGGCCACTGTGCGCAAAGGCGCCGCGACCGCCCGGCCCACGGCCGGAAGGCTTGGACG
GCGCCTCGTACCCAGCCAGGTCTCCCCTACCTGGCCCAACCCAAGCCAGCCCAGAACGCATACTATGTGTGCA
CCAGAGCCCAGGACAGGTTCCCCTCGAGCGATGTACAGGTCCTCGGGTCCCGTCTTCGTACTCAGCCGCGAGC
CTCGAGCCGCGAGCTCCGCTCTGGTCGCCCCGTTGAAATTCCGTGCCCCAGCGTTCGGGGGTGCCCGTCGGCT
GCTCCCTGGGCCGGAAGGTCCTGGGCGGAGGAAGGCCGGTAGCCAAAAGTGGAAGCGCCACAGTGAAGCGGCC
CAGGGCCACCGGGTGAGAAACCTCCCCGGAGGGCAGACGGGGAGACCGAAGCACACCGCACTAGGCATCCAGA
CTGGGCTTGGGAGCCGCGCACCCTCCCTACCCAGATCCAGGATGGCTAGAATTAACGGGTTCTTTCTGAGACC
TCGGCTCAGGCGCCGAAACCGGATAGATCGCGAATTCGCTGGACCCGGAGACCCGACCCGCCTCCCGCGTCAC
CTTCTTCTTTCTAGCTTTGGGCGCGCGCAGCGAAAGGCAGGAGAGGCGCGCACTGGGTGAGTGAGTCCCGGCC
GCTGTCTGCGCTGGACCAGCCCGACTGACCTCGCGCGTAGGGGTCGCGTGAGCCACACCGGTGCAGACGCGCC
TAGATTATTTTTAAATGTTAGAAGGTAAAATATTTGCCTCCAATTAATCTGAAAACTCTCTATTCTCTTGCGC
CCTCGGAGAGGCTGGGGTACGGCGTGGTATTGGGCCGCCTATTTTTAATAAAATGAGTGTATTTTAACTAAAA
CTTAACTCAATCTTGTGGGGTGGCAAATTAAATGCTGGAAGAGCGCGTCTACAACCCTCTTCGAGAAGCGTGC
TCTCCGCAGAAATGAGTCGGCCGCCTGGAGAGAGAGCCTGGGCGGTGCCGCTGCGCAGCCCCTGCCAGTAGCT
GGGGGTTGGGGACTCGCACCTTGTAAATGTCCTCGTCTTGTTTGAACGCAGTGAGAGCACACTCGTTTCCAGA
TCACTCGGGACCGGGTGTCTCGGATCTGTGCAGACTATGTATGGCTCCGGCCTCAGGCGGCCAGGGCGGGACA
AGCACG
CGI: 43 range = chr20: 49542203-49542863
CGCTGGCACCACCGAGCCCCGCCGCACCCCGCCGCTATTCTCAGGACGACCTGGGCAGCCCCCCAGCTTCTAG
AAAAGACACAGAGGAGACTGCGCAATCAACAGGCAGGAGTGTGCGTGAGTGCGGCATGACATGGGCACGCCAC
CCCAGAGAAGTGGGCGCCTGCTGCGCTAAACGTCATCCGTCATCCTTTCGCTGAAAAGTTGGAAAACAAACAA
CAAAAACCCCGCCCAGCCTCATTTAATGCGAACCAAACACAAAAGCCACAGGGGAAAGCTTTTCCTCTCTGTG
CTTCCCTTTTCCGGCCGAGGAACACCACCAGCCAAGATAAGGGGACTGTGCGGGGCCCTCTGCGCGGCTTCAA
AGGGCTGGCACCCGCCCGGGCCCGCTCCCACTCCCACTGGCTAATGGGCTCCCCGCTCCAGCCCTTGGGGAGC
AGGAGGCGGCCGGGGCTCCATGCCAGGCGACTTGGAAGAGGTTTAAGGCTCACGCCACACAAGGGAGGAAGCT
CGGCCTGTCAAGAGGCGTGATAAAGCAGCCCCTTATCGCAGTTTTCCTTTCAACTGCCTCCAAGTGAGCGCCG
GCCGGGGCTGGGCCTGTCAAGGCCAAGCGTGTTCCTTTCATGTCGCCCTGGGTTCCTCGGTCAGCGACGTATC
CACG
CGI: 20 range = chr20: 54411932-54412178
CGCGGGTTTAAGTGGACGCCAGGTGCACCGGACACAGGCTGTGTTTAACCACACCGAGGACTATGTGTTGCTG
CCCGACGAGAGGACGATCAGTCTTTGCTGCTGGGACTCGAGGACAGCCGAGCGGAGAAACCTGCTGTCGTTGG
GGCACAACAATATTGTACGCTGCATAGTGCACTCCCCCACCAACCCCGGGTTCATGACGTGCAGCGATGACTT
CAGAGCGCGGTTTTGGTACCGGAGATCG
CGI: 30 range = chr20: 55680656-55681057
CGCACGCGCACGTGTGTGCCTGCATGCACTCACATGTGTGTTTCCAACCGGCCGACAGTGACGCACGTATGCC
CTCGCCACTCGGCAAGCACCTCGTGCTCCTTGGTAACCAGCAGATGTTTCTCTCAATTACTGATTTTCAAGAG
CCTGGTGTTTCCTGACATGAGCCAGGATGGCGGGCGGCGCCCAGGGGAGGGGAAGTGAACCGGGGCTCCGTTT
CCAAGGCTCTTGGACAAAAAGCGAAGCCCTGGATCAGGAAGCACAATGCGGCTGGTATTTAGCCGCTTCTCAA
TAGTGCCTCATTCAATCCCCGGGGCCTCATTGATGCCCGCCGCGTGCTGGAGAGCCTCTGAGGGTCAGTCGGC
GACGGGCACCGTCTGGAGGGGTCTCGCCGCTAACCCG
CGI: 26 range = chr20: 56860125-56860442
CGCAGCATGGTAGCGGGAGCGCAGCTGCGCGGGCAACCGCCGGGTTTGTGGCCGGTTGGCGGGCTCAGTGCCG
CCTCAGTGGGCTCTAGCAGTAGAAAAGTAAAGCGACTACCCTAAGATACCCAGAGCGAGAGGAGAGGGGCTAG
AAGGGTGCTGGAGGCAGGCTGTAGTGGGGCTAAAGGAGCTGACTGACCAGCGCTGCGGCCGGTGCCCGAAGCA
GCGAGCAGCGCACCTCAGCTCCGGTTGCCGCGCGGCATGGTATTTATCTGTGGGTTCAGTGCGCACAGCGTTG
TCCAGTCTCGAAACCACCCTAAACCG
CGI: 18 range = chr20: 62371744-62371958
CGTGAGTGAGGGCGTGCACGGTGTGGGGTCCTGTGAGTGCGGGTGTGCACGGTGTGGGGTCGTAAGTTCAGGC
GTGCACGGTATGGGGTTGTGTGAGTGCATGGCGTGGGGTCTTGTGAGTGCGGGCGTGCACGGTGTGGGGTCTT
GAGTTCAGGCGTGCACGGTATGGGGTCGTGTGAGTGCATGGTGTGGGGTCGTCAGTGCGGGCATGCACG
CGI: 22 range = chr21: 45511336-45511549
CGCAGGGCCCACGCTCCCGGCCTCTGGGACGCTCACGGCAGCCCCACGAGAATGATCACACGAGGGCCCACGC
TCCCGGCCTCGGGGACGCTCACGGCAGCCCCACAAGAACGATCACACGAGGGCCCATGCTCCCAGCCTTGGGG
ACGCTCATGGCAGCCCCACGAGAATGATCACACGAGGGCCCACGCTCCCGGCCTCGGGGACGCTCACG
CGI: 24 range = chr21: 46892946-46893236
CGCGGCCTAGAGCGGTGAGTGGGGTCTCGAGCGCATCCCGGGTGTTTGTGCCGAGGCTGGTGACGTCCGAGGT
GGCCTCTGAGTGTGCTGACTTGTGACCCTGAGCTGTTGGGGGCTCACCGGTGACTCCATGGTCTTGTTGAGCA
CCCTGCACGTGGGGCTCAGGGTCGGTAAAATAGCAGTGCGTGGAGACCGCGTGCTAGAGGCCGTGGCGCCCGC
GTACAATGAGTCGCAGACAGCACAGACGGGAGTAGGGCAGAATAGACAATATCCCGTGAATTGCGTGGGGCG
CGI: 38 range = chr22: 18453364-18453931
CGCCAGCGCACAGCGCGGCAGGACGCGCCCGGGTCTCAGCGGACTTGTGCATGTTAGCTGTGTAGATTTATGT
GAGGGCTTGTAAAACTCTGGTCTTGTAAACTAGTCTTAAGCGCTTTTAATATGGAGACAGATGAGAGCCCCTC
TCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTGCCCCGT
GAGCAGTCTCCACCACCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATG
GACAGTCCGAACTCCCTGCTGAGGACCCCTTCAACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTC
TAAGGGCCGCCTCCTCATAGACCCGAACTGTAGTGGCCACAGCCCGCGCACCGCCCGGCACGCACCTGCGGTC
CGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATTAGCGTGAGCTTTACCGAGAGCTGCAGGA
GTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCG
TABLE 8
PcG target genes methylated in all bladder tumors or specific subgroups.
All NMI-wt only NMI-mt only MI only NMI-mt and NMI-wt MI and NMI-wt MI and NMI-mt
DLX5 ADCYAP1 BARHL2 TBX3 CNTNAP1 EVX1 HOXA5
DLX6 ATOH1 BCL11B EBF2 GATA2
FOXD2 BHLHB5 FOXA1 HOXB5
GAD1 C20orf103 FOXD3 MSC
HLX1 CACNA2D4 HHEX NKX2-8
HOXA7 CBLN1 HOXC4 SIM2
HOXA9 CBLN4 HOXD3 VAX2
IRX3 CDKN2A MAFB
MAB21L1 COL12A1 ONECUT2
MEIS1 COL27A1 OSR1
MSX1 CYP26B1 PCDH17
MSX2 DMRT3 PCDH7
NR2F2 DPP10 PITX2
NXPH1 ELAVL2 SIM1
OTX1 EMX1 SIX1
PAX9 EN1 SOX7
PITX1 FBN2 UNG2
PRKCZ FEZF1 ZIC1
SHH FLJ46347 ZNF503
SIX3 FOXA2
SOX21 FOXB1
TFAP2A FOXF1
FOXG1B
GATA4
GNAS
GRID1
GZF1
HAND2
HEY2
HMX2
HOXA11
IRX1
IRX5
ISL2
ISLR2
KCNK9
LBX1
LBXCOR1
LHX4
LHX9
LMX1A
LRAT
MAP1D
NFIX
NKX2-2
NKX2-3
NKX6-1
NPAS3
NR2E1
NR3C2
NR4A3
NRN1
OLIG2
ONECUT1
OTX2
PAX5
PAX6
PCDH1
PCDH10
PHLDB1
PTGER3
SEMA6A
SFMBT2
SIX2
SIX6
SLC32A1
SNRPF
SORCS3
SOX17
SOX9
T
TBX15
TBX20
TBX5
TFAP2B
TRIM2
TRIM36
TWIST1
VIPR2
VSX1
ZIC4
TABLE 9
CpG islands (CGIs) methylated in blood but not in bladder cancer. Provided
for each are: ID no.; Coordinates of selected regions containing relevant
CpG islands based on Homo sapiens full genome as provided by UCSC
(hg18, March 2006); GeneName; Location of the probe used; the Fold Change;
and the sequence of the CGIs.
No CGI Gene Name CGI probe location FC
1 chr19: 53930240-53930625 RASIP1 chr19: 053930330-053930374 2.66
2 chr7: 72883371-72883981 CLDN4 chr7: 072883457-072883501 2.64
3 chr22: 26522794-26528592 MN1 chr22: 026525238-026525282 2.21
4 chr7: 5614184-5614510 FSCN1 chr7: 005614143-005614190 2.15
5 chr16: 66239477-66241425 RLTPR chr16: 066241103-066241147 1.93
6 chr5: 551112-551430 SLC9A3 chr5: 000551380-000551424 1.86
7 chr19: 6426223-6426998 DENND1C chr19: 006427051-006427102 1.82
8 chr3: 32836146-32836433 TRIM71 chr3: 032836466-032836511 1.78
9 chrX: 129301145-129301626 SLC25A14 chrX: 129301313-129301357 1.76
10 chr9: 124027565-124030907 LHX6 chr9: 124029663-124029718 1.74
11 chr10: 129424401-129427356 FLJ46831 chr10: 129426989-129427033 1.71
12 chr1: 3147370-3148160 PRDM16 chr1: 003147944-003147988 1.65
13 chrX: 128941527-128945710 BCORL1 chrX: 128944842-128944886 1.64
14 chr17: 7584523-7585036 DNAH2 chr17: 007584859-007584908 1.63
15 chr1: 27548507-27550603 SYTL1 chr1: 027550188-027550232 1.6
16 chr19: 10304689-10307022 ICAM3 chr19: 010306004-010306051 1.56
17 chrX: 129132628-129134108 AIFM1- chrX: 129133196-129133244 1.55
RAB33A
18 chr21: 45648960-45650662 COL18A1 chr21: 045663489-045663539 1.53
19 chr10: 134864694-134865392 KNDC1 chr10: 134865054-134865098 1.48
20 chr9: 129556229-129557670 SH2D3C chr9: 129556146-129556190 1.48
21 chrX: 47305347-47306043 ARAF chrX: 047305953-047305997 1.45
Sequence of the CGIs of
1 chr19: 53930240-53930625
CGTGCGGGGCTGGGGCGGCGGTTACCTGGGCGTCCTGGTAGCCCTGGAGCAGCAGGAAGTAGGGGCGGTTGCTG
GGGGCCTGGATGAGGCACTGAGTCAACTGATCGAAGTCCCCGGGGTCTGCAGTTCCGATTTGGGCGTCGGCTGCC
CCTGGGGCCATGCTAAGTGCCTGCTGTCTCCGCTCCTGCTGCCGCCGCCGCCGCCCCTGAAGGCTAAGCTCCGAC
ACGCTGCGCCGCAAAGACAAGTTTTCTGAGCGCTCCTTGCCTCCAGACCCAGCTGGGGCCCCTGATCCGGTCCCC
GGGCCAGGACTGGCCAGCGCTGCCCCACCCGACGCCGCCCGGGAGCGGTTCTTCTGTGGCCGCCACGAAGGGGC
GCCGGTGCCTGCG
2 chr7: 72883371-72883981
CGAACGTTAAGTCCGTCCCCAGCGCTTGGAATCCTACGGCCCCCACAGCCGGATCCCCTCAGCCTTCCAGGTCCT
CAACTCCCGTGGACGCTGAACAATGGCCTCCATGGGGCTACAGGTAATGGGCATCGCGCTGGCCGTCCTGGGCTG
GCTGGCCGTCATGCTGTGCTGCGCGCTGCCCATGTGGCGCGTGACGGCCTTCATCGGCAGCAACATTGTCACCTC
GCAGACCATCTGGGAGGGCCTATGGATGAACTGCGTGGTGCAGAGCACCGGCCAGATGCAGTGCAAGGTGTACG
ACTCGCTGCTGGCACTGCCGCAGGACCTGCAGGCGGCCCGCGCCCTCGTCATCATCAGCATCATCGTGGCTGCTC
TGGGCGTGCTGCTGTCCGTGGTGGGGGGCAAGTGTACCAACTGCCTGGAGGATGAAAGCGCCAAGGCCAAGACC
ATGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAAC
ATCATCCAAGACTTCTACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGC
TGGGCCGCCTCCG
3 chr22: 26522794-26528592
CGCCAACGTCTTGTCGTCGTCCGCGCTGTCCACCAGGGCCTTGTCAGCGGGCATGTACCAGGCAGCGCTGTGCTC
TGCCATCAGCGAGTCCAGGTCAATGGTGCTCATGGCGCTCTTGACCGCCTCGGAGCAGCAGCTGCCCAGCTCGCT
GTCGCCATTCTGCGCCCCTGAGGCCCCGACGGCGCACTCACCCTTCTTGCCACCCTTCAGCCCCAGAGGCTGGTC
CTCGGAGATGCTGAACTGCTGCCTCTGTAGCTGGATCTGCGCCTGAAGGATCTCCAGGGGGTGGATCTCGTCGGG
TGGCGGGGCGCCGCTGCTGCTCGTCGGGGTGCGGACCTGCTCCAGGCCCGGAGTGCCCGGATGGCCCGGGCCCC
CACCGCCGCCGTAGCTGTCAGGGGTCGAGGTAGAGTTAGACATGATGCCCAGGCCGAGGGCGGGCGGGGGCGCC
TTCGGTCCGTGTTCCCCGGCGCCTACCCCACGGGGAGGGAGTTTGGGCGAGCCGGTCACCAGGGGACTCCTGCTC
GCTTTAACTAGTGCCTGGGGGTTGTCAGAGCTGGACGACACCTCGTCCTCATTGGCGTAGCTCGTGCTCACCTCG
TCCGAGGCGAACTCACCCACGTTTGGCGAACTACTGTCCGACTTGGCCCCGCCGTCCAGGGACCCAATGAGGTCC
GGCTGATCCCCCAGGAGCAACTCAGCCCCCTTCCCCCAGGATGGCGACGTGAGCGCCTTTTCGTGGGGCGTCGGT
GCCCCGCGCGTCTCGCCTGCGGAGCTTCCCCCGACGGCTGCGCCTGACGCTTGCTGCTGCCCTGGGCTCACCCCA
GGTGCGCCCCCGCTGTCCGGAGCCGCCGAGTACTTGTCAAAGAAGGTGCCAGGGCTCACGTGACCACTGTCCCTT
TTTCTGCGACCCCGTCCCCGGCCGCCGCCCCCGGAGACCGGCTTGCCGTCATTCCCCGACGTGGATTCCAGGGTG
TAGTTGGGGGAGAGGCTGGTGCCGTCCCCCTGGGCTGGAGGGTTGGGCGGCCCCGAGGCTTTGGAGCCGCTGCT
ACTGGTCCCGGACGGGCCTCCGGGTCCTGGGGCCCCAGGAGCAGTCCCTCCTGGGAAGTAATCCGAGCCCGGGT
TGCCGGCCACTGCCGCGCCGTCGGTCTCGTTCTGGCTCAGTTTCCTCTTGCCCTCTGGCGGGTTCTTCTTGTTGAA
GGTCACGTTGAGGTTGGGGGCCCCGAGGCTGGCGATCATGTTCTGGCAAGCGGTGGAGAGCGCAGCCAGGCAGC
TCTGGCCGAACAGGTTGTCCTTGGAGCTGGGCTTGTTGAAGGAGCCCAGCGAGAGCGCGCCCAATTTACTGGCCG
AGGTGCGCTGGCTGGGCTGGAAATCAGGCTGCGGCGGGTAGGCACCCCCGCCACCGCCGCCACCAGAGCTGCCA
CCGCCCCCTCCCGCGCTGGGGGGCGAGTTCACGCCTGGACCGCTGTGCGGCGTGGACTGCCGGCCGGCTGCACC
AAACGGAAAGCCCGGCTGGCCCCCGAGCGCAGACGTAGCAAAGTCCGGCGGCGGGGGCCGGCGCTCCGAAGCAG
CGCTGGGGAGCCCCACGCCCGCCCCGGGCGACTGCAGCTGACCCAGGCCTCCCAGACTGCCCCCGAACTGCAGG
CCCGGTGAAGGCAGCGCGGGCACGTGGCCCTCTCCGGGCATCCTCATCGGCTCCTGCAGAGGGCCCCGGAACAG
CACCCCCGAGCCACCAGGCGGAGGAGGGGGCGCCAGGCTGGGGTCGTGCGGGCCACAGTCAGCGGGCAGACCC
GAGCCGCCCATCCTACGGGGCAGCAGGTCTCCGGGCGGCGGATGCGGACCTGAGAACCACGCGCTCTCTTGCGC
CAAGTGCGGCGCCTGCTGCTCGAAGGTGCCCAGACGCCCGGCGCCCGTGCTGCCGCCTTCGCGCTCAAAGTTCGG
CTGGGCCAAGCCGCCCACCGGGCCGCCATGCACCAGGCCGCCCTGGCCCACGTCCCCGGGGTGGCCTAGCTGAG
CCAGGTTGGGCTGGCGCAGCCGCTGCTGCTGATTCCGCGACGCCATCTGCTTAATCATGAGGGCCGCGTTTTGGC
GCTGCTGCTGCTGCTGCTGTTGCTGTTGCTGTTGCTGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTG
CTGCTGTTGCAGGGACTGGTGGTCCGGGGCCGGATGCTGCAGGGGCGGCCCCGAAGGGAAGCTGTCGGGCACAG
GCGGTGTGAACTCGCCGGGTAGGCCTGGGTAGGCGGAAGGGGAGAGGTGATTATCCAGAGCGCCGTTGTGCATG
CTGCCGTTCCACGAAGCGCAGCGGTCCACTCCCGCGCTGCCCGGAAAGTCGAAGCGCGGCCTCTTGGCCACGTTC
ATGTAGGGGGGCGCGTCGAAATGCTGCAGCCGCTGGTTGGGCGCCTGCTGCGGAGGAGGATGCTGCATGCTGAA
AACAGGCTCGGAATAAGGGTGCATGCTCCGGTTCTCCAGCCGGTGGATGGGATACTCGAATTGCGCGTGCTGGCT
GGGCAGCATGGGGCCTCCGTCCTGCAGGCCGCCGCTGGGCGTGCCCGCCTCGCCCTGCTGGGGCCGAGGGAGCG
CAGGCGGGCACGAATTTTGTCGGACTAGAAGCCCGGGTGGCGGCGGCGGCTGCTGCTGTGGCGGCTGCTGCGGG
GGCTGCTGCTGAGGGGGTGGCGGGGCCTGCTGGGGAGGCTGCATTAACGGGTGCCTGGAGCCCACTGAGGGCTC
CAGACCCACAGGCATCTTTCTGGCCCCACTGAACCTCTCAAAGAACACACCATGCTGCTGCTGCTGCTGCTGGGG
CTGCTGCTGCTGCTGGGGCTGCTGCTGCGGTGGCTGGGCGTGCATTTTGGACAAGCCCACCATGCCCGCAGCTCT
GGGCATGGCCGAGGCGCCCGGGAAAGCGCCCCCAGGAACCTGGCGACCCGCTGCATAATGAGGCAGCTGCCCTT
CGGAGTCAGAGGGCGAAAACATGTCAAAATGTCCCGAGGGCGCCTCGCCCGGGTAATTGTATTCCAGCGAGTCGA
CGGCTCCTTGGTTCGTCACCCTCCGTGGCTCCAGACTGTGGGAATCGGAGCCGCTGGAGGACGGCAGGCCGTGG
AAGGAGGCGGCTCGGTTAGGGCTCTGGTCCAGCGGCAGGCATGGGGCCGGCACGGCGTGGCTGGAGGCACCTGA
ACTGTGGAAGTCCGGGAGGTTCCCCGGTCGCTGCGGGCCGAAGCTCTCAGGCCCCTGGCTCTCCGCCATGTGCTC
ATAGCCCTCGGCGAAGGGCGGCTGGCTGCCCAGGCCTCCGGCTGCGCCGCCGTAGCCGAGCAGGCGACCCCCGT
GCAGGCACGAGGCCCCGGGGTCCGGGCCACCGAAGTTGCCCCCAAAGTGGGGGTGATGCTGGTGGGGATGATGA
CTTCCCGGGTGGCCGTGGTGAGGCTGCTGGCCGCCAAAGAAGCCGTGCACAGGCTGCGCTTGCAGCCCCCCTGC
GTGCAACTCCGAGTGGCCGCGCGCGTGGAAGCCGTAGGGCTCCATGTTCATGCCCAAGATCGGGGGTTCGCCCA
GCGCGCTCATAGCAGGATCCACAGGGCCAGGGGGCCCCCCAGTGTGGAAAGCCGGGGCCTTAAAGTGGGTGTTC
ATGCTCAGTCCGGTCTCGTTAAAGTTCCTCTCGCCCTGGCCAGCGTTCCTGCTGTTGACCTGGGGCTCGAATTGGT
CCAGCCCAAACATACTTGGCGGGGGGCAGAGGGGGATCAATAGGGCATGACAGCCGGCTCTCCGCGGCGCGCCT
CCGGCCAGCTACTCGTTCCAGCCCAGGATTGGGCGCTCCGGGACGCTCAGCACCGCGGGGGCTCAGCGCGCACC
TCCACCCCGCCTGATGTGAGGGACGGGGGGCGGGGTATTAGCTCCTCTCCTGAAGCTCCGATTCTGCCCGGGGAG
GGCCTCTCACATCTTGCGAGGCCGCGGGGCCTCTAGGAGCCGTGTTGGGGGGCCCATGCCCCGGGCGGTTGTCA
CAGCCGCGGGTGGGTCTGCGGGGAGGGGACGAAGCCGCGGATGAACGGAGACAAAAAGTTAAGTGGGGGGAAT
GGGGAGGGAAGGGGGTTGGGAGAGCAGAGCGATCACCTTCTCAAGTCCGATTGGGTCTGCTGGGGAGCCCTCAG
GACGCCGCCCGCAGCCTCCCGGAGTCCGTGGCAGAGCTGCTAAGGGCAGGGGAGGGAGACCCTTCAAAGCCGCG
GCTGGCGCCGGGCACCGACAGAGCGGTCCCTCCCCCCGCCCCCCGGAGTCCCCGCGCCCCGCAGCCCGAGCCTC
CACCGAGCACGATCCGCTCGCACAATCCCCGTAGGCTCCGGGCGAGCGGCTGCTGCTTCTTCAGCGGGTCGGAGG
ACTGGAGGCTCCGCTCGGCATCGCCGGTGCCGGCCCCCGAGCCGAGGACGCAGAGGGGCTGCGAGGCGGCAGGC
GCCGGGGGCTGGAGCCGAGGGTCGGGGAAAGGCGCGGCTCCTCTGCTCGGCAGCGGGTGCGCTGCGTTCGGCGC
GCAGCTTCGCGGCCACGTCCGCCGCCTGCCGCTTCTGTTCTCCGCCGTTGGGTGTCTGAGTTCGCCGGAGTCTCC
GCGCACCGTTGCAGGCGCGGGAGGGCAGCGAGACGAGGGGTTGGGTCGCTCCAAGGCTCCGGTTCCCTGCCTCC
GCGCTGAGGTGCTTCGCGAGTCCCTCTCGGACCTGAGGGAGGGGGGCGTACGCGGGTCGGGGGGCCACGCCGGG
CGAGCAGGCTAAGGCGTTCCCGCTGCGCTCTCAGAGCCCGGAATGGGGGGAGGGGGGCGCGGGGGCAGCTCTGG
GGGGTCTGCGCACCCCTCTCCCGACTAGCGGGGGGGCTCTGCGTGGGGCGTTCCGAGGGTCTCGGCTCCCCTCTC
TGTGTCTGCCTCTCGCCCAGCGCCGGGAGAAGCAGCAACAAGTTTTGCATTTCAGCAATCAATTTCAGCCATTACA
TTTGCACCAATCAGCGCCGCCCAAGTTCCGGGCTCGGGGCGGGGCTCGCTCTTAAGGTGGTCCGGGGTCCTGGCT
GCCGAAGCCCCCGCCACGAACCCGCACTACCCCAGCTCTGGGGTCCCCTGCGCCCGCCTCTCCTCGGGGTCCGGC
GTCAGTGCGCTGGGGGCGCGCCCCGGCCTCCGGGCGCATCGAGCTGGAGAGGGTGCAGGCGGAGGAGAATGGC
GGGAGCTTGGCTTTGTTCACCCCCTTCCCATTCACACTGTTCCCAACTCCCCACCCCCAACTGGAGCGAGACCCAC
CGGGTGGGCAGGGGGCGGGGAGGTGGGCGGTGAGCGGTACGGGGCGCTCAGACAATGAGGTCGCCAGGCAAAG
ACCCTAGACTCGCCACGGAAAGTCGCTAAGTGTCTACTGCACTTCGGCTCCGGGGTGAACACTCCGTTCTCCGCT
AGCGGCGCCCAAGTTAGCCGGCCCTGGGATTTTCTTGGAGGGTAAAGCAGACGGGGAACCTCGAAGTTAGGGTTC
TCCTCGAGAGACCTGGGCGCTTGCTCACTCCTCCGTCACTAGGGCGTTCACAATTGTTCCCCTTCCCCACTGCCTG
GGGTTCCCGGTTCTCACCGGCCGGCGTGGGCTCCAAGGAGTCACAGTCACTCAGCCACTTTATGGGGGAGCACAT
CGGTTGAGCCCAGTAACCGGAGCGACTTGCGAGGCGGCTGGGAACCCCGAGAAGACACGCACGAAGAGGGCGCA
CCCGCCGGGCCGCACACCTTGCCCTGGGCCACCCGGTCCAAGACCCAGACCCTCTGCGGGTGCG
4 chr7: 5614184-5614510
CGCCTACCACGTGGCCGAGATTCCCGAGGCTGCAGCCAATGAGCAGCATAGTCCGATGGGGGAGGCTGGAAGGG
CCGTTCACGAGATCTCTCGGGAGGAATCGGTAGGAGCTGCCCAACTGAAAGGGACGGGGGAATAACCCGGGGCG
AGGGACCTGCCCAGGCCCTGCCCTCTGGGGGGAAGCCAGGCCAGGGGCCGGGGGCATCTCTGGGGTCCCAGGTG
AGATGCGGGTCGAGGGAGCCAGGCCACGGTTCTCCAGACTCGCGTGGAGGCCACGAGCGTCTTCTGGAGGAGCG
GGCACTGCGCGGACCGGCAGACTCTGGGGCG
5 chr16: 66239477-66241425
CGTCCTAACGTACTGTCGTTCCTGAATCTCGCAGGCACCGACACTGCCCTGGACACTGTGAGGGGGTGCTCCGTG
GGGGGATGGATGACCGGCAGGGCGGACTGGAGGGCGGGACGGGGAGGGCTCGGTCCCCCCGCGGGTGTAGCCA
ACAGCCTCCCCCCGCAGCTCTTCGCAGCGGTATCCCGAGGCTGCTGCACCAGCCTTACCCACCTCGACGCTTCGA
GGAACGTCTTCTCCCGCACGTAAGGGGGACCTGTCGGGGCCGGGGGAGGCTGCTGGAAGCCGCCTCCTTGCGGC
CCCAGGCCCACCTTCCCACTTCCCCCAGGAAGTCCCGCGCCGCGCCGGCCGCGCTGCAGCTCTTCCTCAGCCGCG
CGCGGACGCTGCGGCACCTGGGCCTGGCGGGCTGCAAGCTGCCGCCCGACGCGCTCAGGTCAGTGTCGGACCCC
GGCCACGCCCCCGCGGGCGCTCCCACCCTGCCCTGGCCTTCGCCCCTCCCCGCTCCTGCTTCTGTCGCTCCCACA
ACCTCCCCCAGATCCTGGCCCTGCCTCCTTCGTTCGCACCCTGGAGCCCCCTGTCCCAGCTCCCGCCACCCCGTGT
AACGTCCTCTCCCAGAGCCCTTTTGGATGGCCTCGCGCTCAACACGCACCTCCGCGACCTGCACCTGGACCTCAG
CGCTTGCGAGGTGAGCGCCGGCCCCCAGAAGAGACCACACATTGGGAGAGGCGCTGGGAGGCGGAAGGGCAGG
GCCGTGGGCCGCCTGCCCCTCCCCACTCGCGGCCTAAGTGGGTCCCACTTCCCACCTCCCACCTCCCACATACAG
CTGCGCTCGGCCGGCGCCCAGGTGATACAAGACTTAGTGTGCGACGCAGGCGCTGTGAGCTCCCTGGATCTGGCG
GATAACGGTGAGGCTGCAGGAGAGCCCATCCTCGCATCATCCACTCGATTCCCAATCCCCACCCTACCCTTGCAAC
TTCGCCTCGTGCGTGACCCGAGTCACCCCCAGGCTTCGGCTCAGACATGGTGACTCTGGTGCTGGCCATCGGGAG
AAGCCGGTCCCTGAGACATGTGGCGCTTGGAAGGAACTTCAACGTCCGGTGCAAGTGAGCCCCCACCCTACTCCT
GGGCCTCCCAGACAACACCCCACCACCCCTGTCCCCCACAACTGCGGCCCCTGCCCACAGGGAGACCCTGGACGA
CGTCCTGCACCGGATTGTCCAGCTCATGCAGGACGACGATTGTGTGAGTTCACGGGACCTTGCAGGGCCTCGGGC
AATTAGACCACTTTGGTCCTCCTTTCTCTTGTTCCCTCAGACCCTGTGACCTGCCCTCACTGACCCCTGACTCCAG
CCATCAATGGCTTTCTCTTAACCCCAGCCTCTTCAGTCTCTGTCGGTGGCTGAGTCTCGGCTGAAGCTGGGTGCCA
GCGTCCTACTCCGGGCCCTAGCCACCAATCCTAACCTGACCGCGCTGGATATCAGCGGCAACGCCATGGGGGACG
CGGGCGCCAAGTTGCTGGCCAAGGCGCTGCGGGTCAACTCGAGGCTCCGGTGGGCGGGGTCAGAGGGGTGGGAC
CAGCGGGCAGGGGGCGCGGTGGAGAGGAGGGCACCGGGCTAAGGGGAGGGACTGAATGAGGCGGAGCAAATGG
AGCAGGCTGACGAGGCGAATGGACTAGGCCGAGGGTTGGGTGGGGCGTTGGGAAGCTCCGTCCCCGACTGAAGC
CAGGCCCGGCCCAGGTCTGTGGTCTGGGACCGGAACCACACATCTGCTTTGGGTCTGCTGGACGTGGCGCAGGC
GCTGGAGCAGAACCACAGCCTGAAGGCCATGCCTCTGCCACTGAACGACGTGGCCCAGGCGCAGCGCAGCCGCC
CGGAACTGACAGCACGTGCAGTCCATCAGGTGGGCGTCCCCCTCTTCCCTTGCCCTTCTCTGCACGGTAACTCCGT
CCCTCG
6 chr5: 551112-551430
CGGATGCCGGCCTCCTGCCTCGGCCACCGCCCTCCTCTTCAAGGATGCTGTTTTGCCTCTGGTCGCTCTATCTTAT
CTTTTTTCTCCGCACTCCTGGACGTCTCTCGGACCTTTCGCTCTGACAGTGGCTTGAGCCTCGGCCGCCACTTCCG
CCCCTGCTACTTCGGGGCCACGTCTCGGTCCGACGCTGAGGGGTGCTGCCAACCGTGTCTTCTCTGTGAACGTCC
TCACGATGAACGCCCCCGTTCCACTTCCCACCCTGGAGCTGCTGCTTCCGTGACTCACATTCCGGCCATTTCCGTG
GTGTGAGGTACGGGCG
7 chr19: 6426223-6426998
CGTTACATTGCGATTCATTCAGGAACCCACGAGACCTCTCCCGCAGCGTCCCCGCTGCTCACCGGGCTGCAGACG
AGTGCGTCGCGGTACCCCCCGAAGAGCAGGGCCTGGGCTTTGAGGAAGAGACGGGACACCCCTTCCCCGGGGGC
CAGGGCGACCTTCCTGAGCCGGAGCCTCAGCAGGGACACCTGAAGCACAAGGGAGTGGCCCTGAGTGGGCAGGT
GTGGGCCCCTCGCCTCCCGGGGCAGGAAGGTGGGAGGGGCGACACTGACCACGTCTGGAGGCAGCGCCTGCACG
TCGTTAAAGGTCGTCTCCAAGGTATTGGCGTCCACGTTCAGCACCACGACGTCCTCCAGGGCTTTTTCTCGTACTC
TCTGCGGAAAAGCGGGGTCGGCCGCTCAGAGCCCGGGAGTCCTTGGCAGAGGAGGGCATCTGGGGATGTAGAGG
AAGGGGGAACCCTCACGTCCCCGTCGTCTGGGTAGATCCACGCTCACCTCGGCGAGACTGGCGTGCACTCCAATG
AGGTAGGGCATGGGCGCGCTGCGGACCGAGGGGACGGGGTCATGCAGGCACCGCCCCCAGGGCCTGCCCACAGG
CCCTGCCCCTCCCAGCTGCCCTCGCTCACCAGCAGTAGTCCAGCAGGTGTGGGGGCAGCGTGGGGATCAGCACGT
GCTCCCAGCGCATGGGGTACAGGAGCGCGCAGGACGCGTGGACGCACGAGGTCAGCTGGGGAGCGATGGCGGG
GCGTGGAGTCAGGGCCTGGACCCTCTAGCGCG
8 chr3: 32836146-32836433
CGTGAAATCGCCGTTCGTGGGCCCACGGCTGCACCCCGAGATAGAAGCGGAATAAAGGGACGACGTTACCTTCAC
CAGCCTGAGTCTCTTGGGCCGCGCCCGCCTGCCCCGACTCCAAGCCCTACAGGAACCGGTTTCCCTGGTTAGGAG
GTATCCACCCGGCTCAACCAGGGTCTCGACTTCCTTGGAAAAGACCAAGGCAGCCGTACGCTGCTGGAACGCCGG
AGTGCAAAGGCTTTTAGGGCTACATTGCAACCCTCGGGCTCGATTTCGCCCTTTGGGCTGTCG
9 chrX: 129301145-129301626
CGTTGCCGCCTTTTTCGTACTGAGCGCGCAGGGCACTACGCCCACCACTCCCCTTGACCCACTCCTCAAGCCCTGA
TACCGGGGCGAGGCCCCTTCCTTTTCTAGTCCTTCTACGCGCCAGGTGGGTGGGTTTCGCGGTGACGAGGCGACA
CCTCTTTCCCCTCTGGCGAGCACGTTAACTGGGGAAGCTACCAAATTCTCACGCCTTAGCTGCCCTGCCTCCACCT
CCCGCAAGTCCGGTTGCCCCTCTAGGCTTCTGCGCCTGCAGTGGTTCCGACCCTCGCCTTTAGAACTCTGCCGCTT
CCGCCTCTTATTTCGCGCCTTTGTTTTTAGTTTTGGAAGGGGCGGAGTTGAAATGGCTGCGCCGCGGTTGCCGAA
GCAACGCTTTGGTTACTTCCGTTGGTTTCAATGCTTCCGGGTTGGCGCTGCAGTGGCGTTTCCGACTGTGGGAGC
CTCAGCTTCCCAGTCGTCCGATGAGCCCG
10 chr9: 124027565-124030907
CGAGGCCCAGGCGAGTGGCCAAGACGCGGCAGGACAGGAGGATGCGCCTGGCTGCTCTCGGCTGCTGGACGCGG
CCTGCAGTAGGGAGAGCGCAGCCCGGGGTAATCCCACTCAGGGCTCCGGGTGCCCAGTTCTCCCACTTCCCATCC
TGGCGGCCTAAAGGCAAGGCCTAGACCCTGGAGAGGCCAAAGTCGGGCCAAAACAACAGCGAAGCTGGGACTGG
AACAGGCGCTGGGGGCCTGCGCATGACCCCAGGCTCAGAATGCGACACTCCAGTGACGCCGGGGAATGAGTTGA
GATGGAGCCGGAGACAGAGGTTGGGGTTCAGGACGAGGCGCTTGGGTATGGGATCGGATCTGAGACGGTTGCGG
CGCTGGTGCTTTGGGCTGGACCAGACTCGAACCCAGAGCGGAGCGAGGGTCAGAGCCAGGGCAAGAGTCCGAAG
CCCAGCTCAGCGTCCAGCCCGCGAGAGACCCCACCATGAATGACGTCCGAGTAGGGTTGGAACTCGAAGCCCGAA
CGCACTGGAAATGCAGCCGGACGACGGCTGGGATCCGAGTGGGTCCGGGCCAGAAATGGGGACCTCAGAGCTCC
ACCGAGGCGCTCGAGGTCAGAACTGAAGCCTGAGACTTAGGCAGGACCCGAGACAGAGCCAGAGACGATACCGA
AACCCAATGGACCGCGAGGACCGAAGGCAGATCCGGGGCGCAAACCTGTGCAGGCACTGGCGCGCTGCCTGGAG
CTCTGGGTTCGCGCCGCTGAGCGCCGGCAGGTTGGACCAGCGCTGCGCGCCGGAAGTGCACTCGGGACGCCGGG
GTTCTGGAGGAGAGACCACACGCCGCAAAAGTGGCCTCCGAATGCGCCCGGGGCCTGCCCTCGGCGACACTGCT
GGCTCGGCGGCCGCAGCCTACCTGAAGTAGTCCATCTTGCAGAAGATCTCCTTGTTCTTGATGTAGCAGCTGTTCT
GCTGCCTCAGCGACGTGCGACACACGGAGCACTCGAGGCACCGCACGTGCCAGATGAGGTTGTTGACCTGGGGA
CGGGGCGGGGACGGAGGTCGGCTCAGCGCGGGCCTCTTTCACTCCGGGCCCCAGCCTTCCCGGTCTCATTTACAG
TCAGAGGCGCTGAAGCTCAGAAGGTGCATGCGATTCCCCTATTTTTCTCCCGTAATACTGAGACTCAGGGAAATG
GAAATAAACTCTTCTTATTTTTCAGACGGAACCCGGGGGCTCAGGCAGACCCTAAGTCTTGCCCAAAGCTTCGCAG
TCGGGCAGCAGTGGAGCCAGGATTTGGAAGTAAGAGGACCTGCGGTGCTTCCCTGCAGTCTCCTGCGCTGCGTCC
CACGCCCCGACAACACGCACGCAACACCTACCCCTGTCTCACCTTGAGCAGATATCGGTCCAGGATCTCGAGGCC
GCAGCTGGAGCAGATGTTCTTGCCTGCAGACGGCACGGAGGAGGCGGCAGAGGGCGGTGAGCAGACAGATGGCG
TGCTGGGCGTACATGGGGAGGCCTGACCCTCGTCCTTGTCCAGAGCTCCTGCCAGGGCCTCGGCGTCAGACTGAG
CCTGCGGCGGGGGAGAGAAGGAGAGGAGCGCTGATCCGGGCACCCAGAGTTGGGGCTGCCTTGGAGACAAATCT
GGGGCCCCCGAGCACCAATTGACAACGAAATCTCCCCAGGACAATGCGCCGTAGACTGAAGGACAGGGATGGAA
GGGCCTATTGGAGAGGAAGGGACGGCCCCAACTTTTAACACGCGCATTCTGGGTGCTGGGAGCGGTTAAAGCCAA
CATTCCCTGCCGGAAAACCGAGGCTCAGAGAGGGGCGGCGCCCGCCGGGAGTCCCCCAGAGCGTGAGCAGCAGT
TCGTGGCCGGAAAACCTGGCCAGGTCCCCAGGGCCGGGCCGCTGGAGGACTGGGCACCGCAGGCAGGGCCAAAC
GGACTCACCATGGCGGGCGGCGCGGTCCCTTCAAGACAGCGGGTGGTCGCTTTGCAGCCGGACCCTGGCTGGGC
CATCACCTGGGGGAGGGGGGGAGGGAACGCAGGCGGCGGCGGCTGCTGAACTGGCTCCGCACAGCCTGAGCCCA
GCGCCTCCCCGCGCCTGTTATATAAACCGGCGCCGAACAATGAGTCCTAACTTTGTAGTGGGCATTTAAAGCCCTT
CCCCACAAAAGCGGTGTCTCTCTAATGAAGCAATTTGAATTTGGATTGGATTTTTTCCCTCTCTCTCCCCCTCTCCC
TGCACTTAACCCGTGGCTCTTGAAGTAATCGCTTAGTTCCCTTGCAATCCAAGCCTCTGAGGGGGGAAGAAAAACA
CGCGCACACACACACAAACTACCTGCAATTAGAAATTGTCGTGAATGCCCAAGATAAGAGGTAGCCAGAGTGTCA
ATTCCAACTGTCAATCAGTGAGATCCATCAGGCCGCCCAAAGAATTGCAAATTTGATTTTTTAATGGTAGTAATTA
AAAATCGAATTTTTTCTCTCTCCACCCGCCCCCCCACCCCACTCCCCTTCCTCGCTCCCTTCTCCTCTCGGCACAAA
ATGCAAAAAGGAGAAAAGAGAGAAAGAAAGAAAATAAAAAAGAGATGGGTGAGGGGCGGAGGGTGGTTGAAGAA
AAGAAAACCCCGAGCGCGGTGAGCACCCGCCCGCCCGCCCGCCTGACACGCGCGGCGAAATTGAAGCAGCTATA
TTGACACGGATTCAGGCGCCTTTCGAGGGCCAGTCGGAGGGAAACCCGGAGCAAAAAGAGAGCGAGATCGGGGC
GAAACGGGACCAAAAAGAGAAAAGAGAGGCGCTCAAGGGGAGGAAAAAGCACCCTCCAGCCCCTCGGCGCGCCG
GGTACCGGCCCCGCGTCGGGATTCTCAGCGCTGCGCCGGCACAACCCCCGGCGCATCGGCGCTATCAGCGCCTAT
TCAGACGGACAATACCGGCCTCGCCTCCTCTTGATTCGCCTGTGTCTTTACTAAATCGCTTTTTGAGAAATTCCTC
CAACATTTGCATAATGTGTTCCCGCTTTCCGCGACCCCCCCCCCCCGCTCGCGCGCGCGCTCCCACACTCACAAGC
ACACACTCACAGGCGCACCCTCGTACCCCTCCTTCCTGCAACCGCCCGCCACCCTGCTCGGCCCGGCTGGGTCCC
GGACCCTGCCCGACCCCGGCCCGGGCCGCTCACCCAGTCGTTCGCCGGCTCACCTGGTCGGTGGCGGGGCCGCC
CTCGGCCGGCAGCCGGCAGCCCTCGGGCAACGCCGGGGCGGCGTTCTCATGCTTCCAGTACATGGGCCGGGGAA
CCTCGGGCTCAGCGGGCGCGCAGCGCGGAGAGCTGCGCCGAGGGGGACCACAGCCG
11 chr10: 129424401-129427356
CGCCTCTTTCGCACAGGTGCCCGACTCGGAGTCCGGGAGGCGGGCCCTCTTTCCAGGTACCCAGCCCAGCGTCAG
CCTGGGTCCATCCTCCGCCACCCCACAGCGCGGGGAGCAGGGGAGGCCGAAAGCCGGGCAGCTTGGGGGGCCGG
GATAACCCGGGCTGCAGCAACCCCGGGCGGCAGCAGGACTGGAGAGCTGGTGTCGGACGCACTGCAGAGACGTC
CCTGTTTTCGGCGCGTCCTCCGACACCCAGCAGAGAGCTTGGCGCTCTCCGCTCTGCGCGCCCGAGGTCACAGCG
CGGAGAAACCTGGCGGGGCCCCGGACTCCCCGGCTTGGGAAAAGCGATGACTGCCCTGAACTGCTGGGGCGTTC
GAAATTTCCAGGGTCCCGACCCTCCGTGGGGTACGCGCGACTTCGGCGCAGATGTCAGTCCGCTGCCTTCCGGGT
TGAGGGAGCGAGGACTCCAGACGACCCCAGGGCCGCTGTCCAGGCCCAGCCCCGCGTTCTCCACCTCGCCACCTC
GCTCTGCGGCTCCAGCCTGGAGATCTACGGACTTCATTGCGATCTCTTGCGCAGTGTAGTCGCCCTCTATCCCTAG
CCCCGAGTCCCGGGTAACCCAGGGGCCCCGGCGAGGCGAGTTTCTTTGGGGCGAGATGTCCCGAGCCGAGCAAA
GGGGCCGCGCATTGGACGGGGCTCCCAAGCCACAGCCCTGGGGGCCTTGAGGAGTCGTGGTACGGTCCAGGGCA
GTCGGGGCTGCGGGGCCCGTGAAGCCAGACGAGGCTACGGACTTAGGGTCCCTGCAACCAAGACCGCGAGCGAC
TGTGGACTCGGGACGGATCGCACAAAGGAGGAAGGGGGAATCAGAGGGGCGTCCGGTCCAGGACGTGTCAGGCC
TGGGCGGGGCGGAAAACTGACACCAGGGCGAGGACAAGGATTTCGCTCCTCCAGGGCTGCCAGGGGAGGGGCTC
GCCACCGTCACTCTCCATGGGCTCTGGCCCCGACGGTGTTTAAAGGGCGGAGGGCTGGGCCGGGCTGGTCGCAC
CCGGGCGCTGCTGGCGGCCAAGCTGGATGGGTCGCCAGTGAGTTTCGGTGCGGCACCGCTGGCCCAGGCCCGGG
CGCGGCTGGACATGGCCACCTACTGCGACGACCTGGGCCCCTCCTCGGCCCCGCCCGGCCAGGCCCAGGCCACC
GCGCACCCCCCGGGCTATGAGCCAGGGGATCTGGGCGCGGTGGGCGGGGGCCCCCTCCTGTGGGTGAACGCGCC
AGCGCTCAGCCCCAAGTCCTACGCTTCGGGTCCCGGGCCTGCGCCGCCCTACGCGGCCCCGAGCTACGGGGCTCC
CGGCCCGCTCCTCGGCGCCCCGGGCGGCCTGGCGGGCGCCGACCTCGCCTGGCTGAGCCTCTCCGGCCAGCAGG
AGCTGCTGAGGCTGGTGCGGCCGCCCTACTCCTACTCGGCGCTCATCGCCATGGCCATCCAGAGCGCGCCGCTGC
GGAAGCTGACGCTCAGCCAGATCTACCAGTACGTGGCTGGTAACTTCCCTTTCTACAAGCGCAGCAAGGCGGGCT
GGCAGAACTCCATCCGCCACAACCTGTCGCTCAACGACTGCTTCAAGAAGGTGCCCCGCGACGAGGACGACCCAG
GTAACAGCGGCGCGCCGGCTCGCTCCGTCCAGGACTCCCCATCTTCCCGCCGGGCCGCGGGCACTCCGGGGGTG
GGAGCACCTTAGACAACCTAATTTCTCCCTGCGCGGTTGGGGATACCCGGGGAGGAGGGAGAAGGGGAAGAAGT
GCTTGGGCATGGACAGGTTCTCAGACAGCGGCTGAGCCCACCACAGGCCCGCGTTTACAGTGCGGCGGTCCCGG
GGCTCTCAATCTCTGTGCGCTCCTTCGGAGGAAGAAGCGGGAGAGCCAGCAAGCTGGGTGACCTTGGGAGTGACT
CAACTTCCCTGGGCCTCAGTGCCCTACCTGGTAAAATGGGGAAGACAGCGCCTACCCCAAGGATGGGCAAAACAA
ATAGGATGCCCGTTTGGAAAGCTCTGGAGCCTACCTGGGGGCCTGGCGTGGTCTGCGCTGTCCTTGGCAGAGCGG
CTGGCGGAGTCCCACCATTAGCATCTCGCAGGCCTTCCTTCACCTTAACGGGGCTCGGCCTTTCCCAGGGCTCCCT
TCCTCCTCCTTTCTGGATTGTCACTTTCTTCCCAGTCCTGCTGTGGAGGCCCATCGGGTACAGAGTGCCCGTCAAG
GGTGGAATGGGGGCGAGGACTCAGACCCTCTGTAAGGGCCAGCAGGGGATCTTTCTGAAGCTGACCTCCTCGCTG
GCTCACACCACGGCCCGTCAAAGCTCGAACCTTCTGAACTGGGCTGTTTCTTCTTCTGCAGGTAAAGGCAATTACT
GGACCCTGGACCCCAACTGCGAGAAGATGTTTGACAACGGGAACTTCCGAAGGAAGAGGAAGAGGAGAGCTGAA
GCCAGCGCGGCCGTGCGCTCGGGAGCCAGGAGCGTGGGAGGGGCCGAGGCGCCAGCGCTGGAGCCCCCGAGCG
CGGCTTGCCTGGACCTGCAGGCCTCGCCCTCTCCATCCGCACCCGAGGCCGCCACCTGCTTCTCCGGTTTCGCTT
CTGCTATGAGCGCTCTGGCTGGCGGCCTTGGCACCTTCCCCGGGGGCCTGGCGGGCGACTTTTCTTTCGGGAGGC
GGCCACCGACAGTCGCCACCCACGCTCCCCAGACCCTTAACCCCTCCCCTGGCTTCGCCCCTGGCCACCAGACCG
CGGCCGCCGGCTTCCGCCTCAGTCACCTCCTCTACAGCCGGGAAGGGACCGAAGTTTGAAGGGAGGCTGGAGGC
TAGCCGGGTGCGGGTCCAGAGGTGCTGAGCTCAGGCCTCCGGTTTCCCCTGGTGACAGCCCCACGTGTTGGCGTT
GAAGGCCTTGGTGCCCTGGGAGGAAGCGCAGAGCCGGGGGCGGCTCG
12 chr1: 3147370-3148160
CGGGGTGCGGGGAGGTTGAGAGCGCGGCGGCCGCTGCCAGCAATCGAGGAGCCAGCGGCGCGTGTGCTGAGGG
CCCAGCTAGCAAAATAAAGAGGGTTTTCAGCGGAGCGGCGGCTCAGGCGAGGCTGGGGGAGCCGGGGAGCGCGT
CCCGCCATTTTTCCAGCCGAGGTCAGCAGCGGGTGAAGGGGCGGAGTCCGTGGTGTTCCCAACTGCCCAGGCGG
GCGGTGAGATGGGGCAGGCGGTTCCGCAACGCGGCTCAGGCCCCAGCGCCCTGCCTGCAGGAGGCCGCTTCTTT
CTCTGTTGCCATCGGGCGCCGGTTTCCTCTTCCGGGGATGCAGGGCAGCTGGGGGGGCTCTGCCTCTGTGCGGCT
CTTCCGTGGTTCCACGCTGGGCTCCGGGGTGACCACAGTCCTCAGCAGCCCACACCCTCAGCCCGAAGGGGGCCC
AGGCCCCGTGCCCAGAGGATCCAGAGAGACAGCCGGGAGCCCAGCAGCTGTGGCAGCTGCCCCCACCACCACCC
CGGGGCTGGCCAGGTCCCACCTCCTGACGCCACACGGTATGACTGGGCCCTCCTGGTCAGTGCGTCGCATGTAAC
GCCTTCAACTATTGGGGCCGGTGTTGGAGCATCCGTCTCTGCGTCCCCACCTGATGACAAGCTCCGGGGAGCAGG
AGTGCTGGCCAAGCCCACGCACGGACCAAGCCCACGTCAGACTCCGCCAGAAAGGCAAGAAGGGCCTCCGCATG
GCGTGACGGATGGGTTTATGGGGGCATTCCATCCCACCCGGACGCTCG
13 chrX: 128941527-128945710
CGGAGCTTGAGCGCCAGAACCACGCACTGAGGTCGCCCAGGGTGGGGAAGTGGGGGGCCGGGGGAGGGGCGGG
GCATCCGGCGGGGAGGTCTCCCCCACCGCATGCAAGACCCTTTGCCCCCCCACAACATACACTGAGGCTAAAACG
GGGATGAGAGTCACACAGAGCAGGAGCGAAATCTTTCGCTCTCCGACCCGAACGGCGCGTTGCTCGACCCCCCCC
TTCCTGGAGCCAGGGGCTGGCCGAGGAAGGTGGCTCCGTTCTTCCCCCGTGGCCAGTGCGGGGTCTGCGGCTGC
CCGGCGAGGTTCCGGCTTCCCCGGGACTGGCAGGGGGAGCCCCGAGAACTGCAGGCCCGCCCCCCCTTCCTCCT
CCTCCTTCCCCTCCTCCCCCACGTGTCCTCCCTGAGCCCAGCAGCCTGATCCCAGCACCCCCCGCCACCTCCCTCC
TCCCGCTTCGCCCGCTTCCCCGGCGGCGTGGAGAAGAGCAAAGTTGCGACAGCGGCCGGGGGCTCTGCCCAGGT
AAAGGGGGCGCCGTGAGGCGGGGGTGGTGGGGGAACGGTGCGGCCCTGCGGCGGGGGCGGGGGGAGGATAAAG
AAACTTGCTTCCCGCGGCCCCCACCCCGCGTGGGTTCCGATCTTGCGTGGAACGAGCCCGCGTGGCGAGTCGCGG
CAACACTGCCGGGACCGAGGCCGGCACCTGGACCCGGACCCGGACCGCGCGCTTGGGCCGGCTCGGCGGGCGCA
GGCAGCGGGCCAGGCCAGCACCCAGGCAAGGGCGGGGTGGGTGGCCGTACACCGGACCGAATCGGGGACTCCG
GTGGCGTGGGCGCGGGCCGAACCCCGACCGGGCCGAGTTGGGTGGCGAAGTAGGACGTGGATTCGGGGGCGGG
GCGCGGCGGGAGGGGGAAACCAGGCCTGGCCAGACTGGCCTGGGCGTGGGGGCGGGGGGCGAGTTCGGGGCAC
TTGCTGGGCTCTGGACCGAGCGGTAGGGCGGGGCGGCGCTAGGGGCTGGGCCGGACCCGCAGGGAGAGGGCGA
GGGGAGGGAGAGCCGGGGGTGGAGTAGGGGCGTGGAGTTGTGAGCGGGGTCTGGCCTCGGCCGGGGGCGAAGG
TAGATCGGCGGGGCCGCGAGCGGAGGGAGGGAGGCCCGCGGCGGCGCGGCGGCAGCGAAGGCCAGCTTCCGCG
GAGTTTGTGCCCGGGCTTCCCGGGCTCTGGCCGCCTCACGCGCACAAATGGGGCTAGGGGACTGAGTGGTAAGC
AACTCCGAGTGTTAGACGGTGATCGGGCGGCGATTCCGGGAAAAGCGAGGAAAGACACAGTCTGCGATTGTGCC
GCACCCCCCACCCACCTCTTAGCATCTGGATTCTGCTCTCGTAGTGGGGGCCGCGGACCCTCCCCGCCACAGTCC
TTTTACTCTCCAGCACTCCCACCGCCTTCCCCCTTCTTCAGCCATCTGACTCTCCTAGGGGTATGTGTTTTTGGGG
GTGGACGGCGACGGGGGTGGGGGATACTTTCCTTCCCGTGGCGGCAACCTAGTTCGTATCTTATTCCTACAAGGT
AGCGTCGCTTCGAGTCGCATGGACATTGGGGTTTAGATAATTTACCCCCCACCCAAGCGATTTAATGGCTTTTAAG
CAAAAGGCGAATACCTGGATTTCCATGGGAGGGATGAGGTTTGAAGATTGGGATTCACCCCTAGCTCACTTCCAC
TACCAACCCCTCTTTCTTGTGAGCCACTTCCACGGGTATTCAAATCTGGGGGGGAGGGGGGACGGGAGTATTAAT
ATGCTTCTCTATTTCTACACAGGGTCGGCGTGGCGAAGGACGGCTAGCCTTGGAGGGAAAGTAGCCACCAGTCCA
ACTCGGGTCGCCCCCACCATTATTTCGGTGAGGGGGCAACGCTAAGAAGGGGATACTGGTGGGTAGGGGCCCAG
TATAAGGGAGGGGGCTGGGTAGTCGTCCCCAGAAGGACTCCGTGTCTTGGCGGGGAGAGAGAGAGGCGAGCCCC
GGCTTCAGGGGAGGGGTTCCGGGGAGGGAGATGGGGGGGTGGCGACGACGGTGGGGGGGGGAGCGGGAAGAAG
GGGGAGTCACGCCCTGCCTGCAAGGGGAGCCTCCCTCAGGCCCCTGGGAGAAGGGGACTGAATGCGTCTGTTCT
CCGCTGCCCGGCAGAGGAGATCTGGGGTCTCGAGATTTGCACACTGGATCGGCACCAGTGGCCTGAGAAAGTCAG
GTCGGGGCATAAGGTGGAGAACGTTGGAAGAAAGAGAGAGAACCCTTTGGCCGCGGCTCACTGACCCTCTCCCTT
CCTCAACCTCCCCCTTCGAGGGGCGTCGAGGTGGGGGGGGACGTGGGGCTCCTGCAGCCCCGCAGATTGAGCGC
CTCCGCCTCTCCCAGGAGTCTAGCTTTTTGCCCGGCTTGCTGCAGCCACTGCTGCCTCCCTCTCCGGAATCCGCTC
GGTCCTCTCAGCGATCCCCTCCTCCTCTCCTCCCCTCCCAGTGTCACCGGGGCTGCTTGGCTCTGCCCCCTTCGCC
GCCGCTTGCTCCCTGCTTTCGTCCCTCCCTCTCTTGCTCGCTCCCTCCCTTCGCCTCCTCCTCCCCATTCCCCCCCA
CCCGCGTAGGCCGCATTCTGGGAGTTGTAGTCCGGTGGAGCGGGGGTTGGCGCCGCCCGCGGACCCAGCCGGAC
TCCACTTCCCGTCGAGCCCTGCGACCGGCACCCACTCCACCAGGCTTCGCTCGCACACAGACACACACACACACC
GCTCTCCCCCTCACTCTTTCGCTCGCCGCGGCTGCTGCCAGTGTGTGGCTCTGTCTCTCCTCCGCTTTGCTGAGCC
CTCCCTTCTTCCTCTCAGTTCCTAGAGTCCGACCGCCGCCGCCGCCGAGAGAGAGGAGAAGGAGGTCGGTGGCGA
TAAGGGGCGGAGGGGGGCATCAGATCGGGGCAGTATTAGGCGGGTGGCGGTTAAGAGGGAGTAAGAGGGAGCC
CGGGTGGCGGCCTGAGCCTCCCCGCGGAGCCGACCCGGGAACAGGTGCGTCTTTTTTCTCTCTCCCCCAATCCCT
CCACCCCTTTTGACTCCCCGGCTTTTTCGTATCCCCCCACCCGCTTCTTTCTATCTTAAGCCTTTCTCCAACCCTGT
TCCTTCTTTTCCCTGCGGCCGCTCGGCTTGCCCCCCGGGGGCGCCGTCCTCTTCGTGTCCCCGGACGTAGCGCTC
CCTGGAGCTGGGTATGTCTTCGCCCCTCCCTTCGGGACAGCTCCCTTCCACTTCCCACCTTCGTACCCCATCCCCT
GACTTGCCCTACCCCCTTCTCGACCCCCTTCTCTCTTAGCCAGGTGAGACTCGTTCGCCACGATCCAAGAGAGTCT
TCTTCCCGGCTGGGCGGGGGTCTCCATGGAAACGGGGGTCGGTTGATCCTGGGGGGGAAACCATAGGAATTACC
CCACTCCTCGGAAAGGGAGGTGGAGGCTATGGTCTTGTTAACTACCTGACTCCAACCCCCGATCCAAGGATCCGA
CGATCCGAAGGGAGGCTGGCTAGCAGGGCAGGGCGAGAAAAGGCTTTTTTTTGGGGGGGGGGGGTGTCCGTGAT
GAAGTGTTGAAGAGACCGGGAGAAAATGCCCTCCAACCTCAGAGGGGAGGTGCGACGGGTGCTCTTCAGGGCTG
CTTTCTTCCCGGCGCTGGGGTGCGGGAATCGTAGGGTAAGGGGTACCCCTAGGTGGCGGCGGGGCCTGGGTTCG
GGAGTGGGAGTGCTGTGATGGGGGCAGGGGCAATTATCCGAGTCCCTGGAAAAAAGGCGGGGGATGACTTCGGA
GCGCCCTGGCTCCGCTGCCCTCGCTCTAGGGGCGGGGGCCGCCGGGCCGGGCGCGGCGGGGAGGGGGCTTAAAT
TGAAGGAAGATGAGATCGGGGGCAATTCATACTAGCACCGGCAAGCCAGAGGGGAGATCCGGCGTGCAAGCCCT
CCACCCGCTTCGCGCCAGGCCTGGAGGCAAGGGGTCGGCGAGCGAAGCCGAGGGCTGGAAGGAGGGAGGCTCC
GGTTACGGGGCCGGGTTTCGGGATCAGGGGCAATCCCCCGGCCCTTGGAGAAGGAGGGAGAGGGATGGCCGCGA
ACCCCAGGGCTCCCCCACCCCGGGTCCTAAGGGGCGTGAGGGACGGACAGCAGGCCCAGCGGAGCTGGATTCGA
GCGGATCGCGGCCG
14 chr17: 7584523-7585036
CGAGTTGGTGCGGGACGTGCCGCACGGCGTGCTTCTGCTGGACACCTTCCACAGGCTTGCCTCCCGCGAGGTGCG
GCTGCCCCGCGGCTTCCTCGGCTTCCCGTCCCGCGTGCTTTCCTGGAGTCCCTCCTTCCGGAGGCCCTCCTGCCTC
CACGTGTGCCCTTCTCCATGTCCAGCATTCGGGCGCCTCTTGTCTTTCTTCTGTTCCCTGGCTTCGGCGTCCCCGG
GAGTGTGACTCCCGCAGCGGGGTGCAGCTTTCCTCTGGGATGAGTGACCGGAGGGAACCCGCCTTCCCGGGCAC
GTCGCCAGCCTCTTCCTCTTCTTCCCTAGGCTATCAAGCGGACTTATGACAAGAAGGCGGTGGATCTCTACATGCT
GTTCAATAGCGAGCTGGCCCTGGTGAACCGTGAACGGAACAAGAAATGGCCAGACCTGGAGCCCTACGTGGCCCA
GTATTCCGGAAAGGCGCGCTGGGTGCACATCCTCCGGCGTCGCATCGACAGAGTCATGACCG
15 chr1: 27548507-27550603
CGAGGAGGCTGACCCGGAGCTGGAGCCCGCGTCGGGGGGAGAGCAGGAGCCGCGGCCCCAGCAAGCCCAGGTA
GGCGGGAGTGGCCCGTGGCTGCTCTCAACATCCGGAGCGGACTCCGGGCGGGGAGCGCTCCTGCCCAGGGCTGC
GAGCCGCCCGCGACCCAGGGCGCTCGGGGCAGGGGTGGGGAAAGAAGGGGCGCCCCGTCACTTGCCCCCTCTGC
AGACCAAGGCCGCGTCCCAGATCCTGGAGAATGGGGAGGAGGCCCCGGGGCCCGACCCCTCTCTCGACCGCATG
CTCAGCAGCAGCTCCTCGGTGTCCAGCCTTAACTCCTCCACGGTGAGGCGGGAGGGAGGGGACCCGGGCGGCCG
GGGGGTGGACCCGTTCCGATGCGTAGCCCCTGCCTGCCCCTCCCTCGCCGCGGGACCCACCGCTGCAGCCCCCCA
GCCTGCCACCTATGACCCGGGTCTGAAGCCTCCGCGCTGCCCGCGGCCCCGACGTGAGCCCTGCGAGCGGCCCT
GACTCCCACCCACTCCCGTCCGCAGCTGAGCGGCAGCCAGATGAGCCTGTCAGGCGACGCGGAGGCGGTGCAGG
TCCGCGGCTCCGTGCACTTCGCGCTGCACTACGAGCCGGGCGCCGCCGAGCTGCGCGTGCACGTGATCCAGTGCC
AGGGCCTGGCCGCCGCCCGGCGCCGCCGCTCGGACCCGTGAGTGCCCCGCCGGCCAAGCGGGGCGCGGCTGTCA
CAGCCCAGCCCACCATTCACAGGGTCTCGGCCTCCTCGTCCTCATCTTCAAAATGGGAACAACAGCGTTATTGGGA
GGCGTGCGATTAAGCGAGACAATCCCTGTAAAGCGCTTAGCACGAGGCCTGGCACGTGTTCGGGATGGTGGCTGG
GGGAGCCCACAGGCAGGGGAGAAGGCTCTGGGAGGGCCCCTCCTCACCTCGGGTTCTCACCTCCCCAGCTACGTC
AAAAGCTACCTCCTCCCGGATAAGCAGAGCAAGCGCAAGACGGCGGTGAAGAAACGGAATCTGAATCCGGTTTTC
AACGAGACTCTCCGGGTGAGGCTGTGACCACGATGCGGTTCCCCGTTAATGAACTGGACGCCCCCTTCCTGCGGG
GCTAGGTGGCAAGGGCAGCCAGTAACGTCATTGCCCGGAGGATCGGCGGAGGGGGCCCATTAACTCGTTATCCA
GTGTTGTCAGCCTCGTGGTGGGCGTGGTGATAGTGCAGGTCCCCATTAATGCCCTTAGGGGCTCCCCAGAATTCC
ATCATGGTAGGAACGCGGTAGGACCTGCCTCAGCCAACTCGCGCAGCATCTACGCGGGCCACCAGCAGTGCTCCA
CTAAAGCTCACCTCCTGTCCTCAGTACTCCGTCCCGCAGGCCGAGCTTCAGGGCCGCGTGCTGAGCCTGTCTGTG
TGGCACCGCGAAAGCCTGGGTCGCAACATCTTTCTGGGCGAAGTTGAAGTGCCCCTGGACACGTGGGACTGGGGC
TCTGAGCCCACCTGGCTCCCCCTGCAGCCCCGGGTGAGGCAGCCAGGCCGCGTGGGGAGACCTGCGGCCCGGGT
CTCCTGCATTTACCCCACCAGGCTCTCCCGCAGCCCCCTCACACCCCGCCTTCGACAGAACCTCCCCTCAACCTCT
TAACCTCATGGCCCCAGGCGAAGCCCGGCCGGCCACGGCCCCTTCCCCGAGGGCGCTAGGACCCCTAGGTTCTGC
CCCTGCAGGCCCCGCCGTCTCTTCTAGCCGCACCCCATCCGGGTCTGCAGACCCCACCCTCCTGAGGCCCCTTTC
CATTAGCCCCTGCTCCACGATAAGCCCGCCTCTCGCAGGTCCCACCCTCTCCCGACGACCTTCCGAGCCGCGGGT
TACTCGCCCTGTCCCTCAAGTACGTCCCCGCCGGCTCCGAGGGTGAGTGACAGCCGGAGAGGCCAAGCTGGACAC
GCCCTGAAAAGCGGGAGACTCCAGTCCCCGGGTTTGGGGGCGGTGGACTCCATCCGTGTGCGGGCCTGAGCCGA
GCCTCTCCGCAGGCGCAGGACTGCCCCCGAGCGGGGAGCTGCACTTCTGGGTGAAGGAGGCTCGGGACCTCCTG
CCGCTGCG
16 chr19: 10304689-10307022
CGCCCCCTTCCATTCCCCGCCCGCTTCCATCACTTGGTGTCGCCCAAGCCTGTGGTCGCCCCTAGCAACGCCCTCC
CTCACTTCGCAGTCGGTTTCCCCTTTCATCATCGCCCCCCCACGTCCCGCTCTTGGTCTCTCCCGATCCCGCGTGG
ATCCGGTGCTTGGGCGCCCCCGCCAACGACCCCCGCGCACCTCAGCGTTGGTGTCGCCCGGTTCCCCCCGCGCAC
GCGCACCGTGGTATTTCCCGCCACGCTCCTACACCGCCCCCCCCAATACCTGGTTGGTCACGTCCCCCGGGAGGC
CCCGGATCAGTATCTTGCGGCGGTTACGGAACTGGCGCTCGGTGTGTTCCAGGCGTTTCCGGATCTCTTCTGGAT
CTAGAGGCGGCAGCTCTTCTTCCGGCGCCCGGCGCTCCGCGGCATCGCCGGCTTCGACTTCGGCCCCAGACTTAG
GGCTCAGCGGGGGCCGGTGAGTAACGGACACGTCCGCCGCCATCTTGGGAAACCCGGCGCCTTCTGGGACCAGC
GAGCCGGGGCGGAGCGGCATAGAGCGGCAACGAGGGCGCGCCCGTCGATTGGCTGGGAGAAACCCCACCTCCTT
CCCGCCCCCCTTGCCCCGTTGGCTAAGCCCCAGCCCACCTCTCAAGAGTTCAAGCTGCGTCTGCGCGCCACAGGC
CCCGCCCCCTTCCGTCGCAGCGACGCTACTCAGTGGATGTGCACCTGGGTGGGAGAGACTTGCAGCGCGGGTGG
AATCAAACCACAGATTAGGGAGTTTGAAGGCTTTATTGGTGCGGAATCTGAGGGCACAGCCAAGCCCCCGCCAAC
TTTGATCCCGGATCCCAGCGTCACTCAGCTCTGGACGGTTCTTCCCCCATTGCTTCTGTCGGCTGCATAGACGTGA
GGGGCAGATAGGTGCTCTCCTCCCTAACATGGTAACTGCCGCTCCGTTGGTGCTCCCTGAAGACGTACATTAAGG
CCAGTACGATAGTCACCACGCCCAGGGTCAGTAACACCGCCACGAAGACGGGGACAAAGTGGGAGCTCCCAGCT
GTGCAGAGAAAGCGCTAAGTCAATATGCGTCCCTTCTGTCTCCAACCCCCCCGCCCCCCGGCTTACCGGTCCAGA
CCCGCAGCCCCGTGTTAGCTCACCCTCAATGTCCATCACCACGACCAGGGTGTATTTGCCTCGTGAGCTGGACGC
TTGGCACTGATAAGTACCATTATGTGTTACGTTGACGAAGAACGGGATCCCCACCGGCACCTCCCGGCTGGAGCC
TTCCTTCAAACACCGCAGCTCGGGGTACGGGTTGCCCCTGGCTTGGCACTGCAGGACGTGTCTCGTTTTATCTTTC
CATTTCAAGTGCTGGGGGCATGTGGCTCGGTCAATTTTGGGACCATCTGTGGAACCACCATGTGTGATCAGACAC
CCAACACACCCGAGGCACAGTGGTGCAGAGGAGCGTCTAATCTTTCCAGGGCAGGGGTGGAGGGATTAAAGGTC
AGGGTGACCGACTCACACAGGACTCGCAGCTGGACGCTACTGTTCCTGTGCAAGAACTCGCCGTCCACCTCGAGA
GTGGCACTGCAGAAGAAGCTGCGTCCGTCGTCACTCTCGGTAGCATTTAGCTGAAGTTGAGCTGGCTGCCCCGGG
GCCGCGGCCGGAACTCCGTCCAGCGTGACCTGGACTCGAGCCCCAGCCATGCAACTCACGGTCACTGTGGACCCC
TCATGGGCGGTGGGCTCGCTGAGGTTCACAATGGGTCCTAGGAAGCCTAAAGGCGGGGCATTGCCCAGGAGCTTA
ATGAACAGGACCTTCCTGTGGGTCAAGCCGCTCCCTCCGCCCTCCCCTTTCCTCTCGGGATATCCGGGCCACGCTT
TCGGCCGTTCAAGCCTCGCCCTCTTTCCGCGCTGTGTCCAGCTTCGGGCACTCAGGCCCAACCCACGTTGCAACT
GCTATTGGGGCAAGCCAGGCCCCACCTTTTCGGCTAGTCTCCGCCCCCTCTGCCACGCCCCCAGACTGCTGAGGC
CGCGCCCCCTTCCCACGCCTCCTCTTACTAAAGACCGTCAAGTTCTCCCGGGCCTCCCGTCTCTCGCCCCCTAGGG
TCACGTTGCAGACGATCTCCCGGGCACCCTCCTGATCCGCGCGCGCCGTGGCTGTGGCTGTGGCCGTTAGCGTGT
CCCCGTGGTTCATGACTGTCGCATTCAGCATCTGGTCCCCCAGCGCCAGGTAGACCTGGGCCTCTGAGGCTGGAA
AAAGCCCGTCTAGGGTGCAGTCCACCGGCCACGACGTTTCCACCTCCAAGAACCGGGGGGCCACGAGGCGCGGG
GGGGTCACG
17 chrX: 129132628-129134108
CGCGGCGGGCCTTCCCCATTGGCCAGCCAAACACAACCGACTGCGGCAGCCAATAGGAGCCGCTCTCCTGAACAT
TCAGAGGATGGGTGCGCGTGGTGTGATAAGGGGATGTTGGCGCCTGGTACGCGCCCCCCTACATCTGGCAAGTCT
GTAACAGAAACAGTTACACCCCCTACACACGCACACGCGTGCCCGCTGGCTCCCTCCTCTCAGCTGTACAGGCCC
CGGACAACCCACTGCGTGTCTTGGCAGCGGCCTCCCAGGCTGCCTGGGGCCCGCGAGTGCACCTGCTCACTCATT
AAGACAGAGCATCCCTTTATCCCAAGGCGCGGGTCGGGTAGAGGGTGGGGGTAGAGGGGACGGGGTAGCGGGGA
CCGGGAAGGCGCGGCTCAGCTGCCCGCTGCTCCCGAGGTGAAAGAGGTGCCTCCGCCCCCACCCCATCCCCGCA
GAGTTGCGTTGCTCCAGGGAGGCCGAAGTGATCCAGTGATGTCTTAAGGTGCAGCTCTTTGTCCTCCCCAGCTGT
GCTCCCTGCCCGCTGACCCCGTGCGCTCGAGCCAGTGGGGGTGGGGAGCCCGAAACCTATAACATAAACGGGGG
CAAGGAGAAAGAAGTCTATCCCGGGGTGGCGTGTGCCGCTGTCCCCACCCCGTCTCTTTCCTCCTGAGGCTTCTT
CCCTCGGGTCCGTCCCGGGAATGCAGGCAGGGGAGGGTGTGGGCCGAGGCGCGGCGGCGGCTGGAGCAGCGCG
GTAGGGTCCTTCGCCAGAGCATCCGGTCCGAGGGCGCACACAGGCAGAAGGCTCGCGGCTCGTCCACTCTCCTCC
CTCTCTCCTCCTCTCCCTGGCTTTTGTGTTGGTGCCTCCGAGCTGCAAGGAGGGTGCGCTGGAGGAGGAGGAGGG
GGGCCCGGAGTGAGAGGCACCCCCTTCACGCGCGCGCGCGCACACGGTGCCGGCGCACGCACACACGGGCGGAC
ACACACACACGCGCGCACACACACACGCACAGAGCTCGCTCGCCTCGAGCGCACGAACGTGGACGTTCTCTTTGT
GTGGAGCCCTCAAGGGGGGTTGGGGCCCCGGTTCGGTCCGGGGGAGATGGCGCAGCCCATCCTGGGCCATGGGA
GCCTGCAGCCCGCCTCGGCCGCTGGCCTGGCGTCCCTGGAGCTCGACTCGTCGCTGGACCAGTACGTGCAGATTC
GCATCTTCAAAATAATCGTGATTGGGGACTCCAACGTGGGCAAGACCTGCCTGACCTTCCGCTTCTGCGGGGGTA
CCTTCCCAGACAAGACTGAAGCCACCATCGGCGTGGACTTCAGGGAGAAGACCGTGGAAATCGAGGGCGAGAAG
ATCAAGGTGATCCAGGGGGTCAGGTCCAGGAAGGGTGGGACCCGGGAGGGGACCTCGCCCGAGGCATAGCTCTA
GCGGTTGTCGTCGTCCAGCGTCCAGCGCGTGGCGGTTTCGCCTCTTGCTGAGCCGAGGACCCTCG
18 chr21: 45648960-45650662
CGCACGCCCCTCCTGTCTCGCGTCCGTCCCTCCGTGCAGCCGGGGCAGGACCCTGCAGGGGCCTTGCGGGCCGG
AGGTGCCGGCTTCCTCCTCCGTCCCGTCCCCCCCGCGGTGACTCTATTCAAATCTCCCCCCTTCCCGCTGCCCCAC
CGGACTCAGGGGCTGGGGTCGTAGCCCGGCGGGCAGCGGTGTTCACCTTCCGCATAAACCTGGGCTTCCTCGCG
GGGCAGCCCCCGGGCCCTGTGCTGGGTCGCAGCCTCGGGCGGTTCCCTCGGGGCGGGACGTGTCCCCGTCCGTC
CTCGCCCGTCCCCGCCGCCCCCGGGTCCCGGCCCGCCCCGTCCTCGCAGCCGCAGGTCCGCTGCGGCGCCCGCC
CCCCTCTCCCCTCCCCGGGCCTTGCCCTGCTCGTCGCTCCGCCCCCTGCCCGGCCCCTGCCCGGCCCCGCCCCGC
GCCCGCCCCCTGCCCGCGCCCGCCCCGCCCCCTGCCCGGCCCCTGCCCGGCCCCTGCCCGCCCCCTGCCCGGCCT
CCCAGCGGCGGCGGCTGCAGCGCGGCGGTCCGAGCGGGTGCACCGCGGCGGAGGAGGCAGCATCCCGCGGCGC
TGACGGTCCTGGGGAGAGCATGGCGCCGAGGTGAGGCCGGGGCTGCGGGCAGGGGTTGGGGGACGCCAAGATG
CGGCTGCGGGGGTCGCGGGGGTCGCGGGGCTCGGCCGGGTCCTGCGGGGGTCGCGGGGGTCCTGCGGGGTCTG
ACCCGTGCCTGTCCCGCGCAGGTGCCCCTGGCCATGGCCGCGGCGGCGGCGCCTCCTGGACGTGCTCGCGCCCC
TGGTCCTGCTGCTCGGGGTCCGCGCGGCCTCCGCGGAGCCAGGTAAGACCCGGGCGGGACGGGAAGGTTCGCGC
CGGTGCCCGCCGGCCTCGCCGCCCTGGCTGGGGTCCCCGCCCGGCTCCCTCACCCCCGCCCCGGCCGCTCTGGG
TTCAGCCCCGGCCCTGCCCACGCGCGCAGGAGGCGCCGGAGCCGGACGGAGCGGGGCGGGGTGGCCGGAGTCC
CGCCCATTCATTCTCCCCGCGGGGTCCGGGCCGGGAGGGGTGCGCGGTGCGAGCGGCCGGAGTCCCCGCGCGGG
GACCGAACCTCCGCGGCCGGCGGGGTCGTCGGTGCCGGGAGGGCTCGGGGCGGGGCCGCGGGGTCTCGGGAGA
CGCGGCCTCTGTCGCCGTCACGGCCTCGTCCCCGCAGCGCCGGGTCCCGGGACTGACCGCGGGCGGAAGGCGGC
GGAGCGCGGGGCGTCGTCTCCGCGTTTCCAACCTGTTGAGGCTCCTCGCCGCGGGCCGGGCCTTGTGCGCCTCTG
TCCCCGCCGCCCTCAGGCCTCTGTCCCCGCGCCCGCCGTGGTGTCGGGTTGCGCGGTCCCCTTTGATGCCAACCG
AGCGCCGCGCGGTCCGAGAACAATGCCCAGAAGCCGCTGCCCCGCCGGCCTCGCCGCTTCCCGTGCGCGGCAAA
CGGTGCGCGGGGCCCGTGGGGACCTTCCTGCCTCCAACCCCGGGACCCAGTTCCCCACCACCTGCTAACCGGGGC
CTCCTGCCTCCAGCCAGCCCAGCAGAGGCCCGGGGGAGGCGGCGGGGACGCGGACCCCAGGGGAGCCCCGCCCA
AAGGGCCTGGGTGCCTTGTCGCGGGTGGAATCCCACCCGGGGGTCCACGCAGCCAGCGCCTGCCTCCGACTCG
19 chr10: 134864694-134865392
CGAGGACAGGGCCCGGCCCCACCCCGGGGCGAGTACGAGTTTGGAAGCAGTGAGGGCGCAGAGTGGGGCTCCAT
CTGGGGAGAGGCCTCTCTCTGTCACCCGGCCCCGTGCGGCAGTTCAGGGTCCCAGCATCTCCCCTGCACTGGGAG
GCGGCAGCCGTGCCCGGGGGGCGCCCGTGGTGGGCGGGTGCAAGAGAGAAGGGCGTCGGGTGTGCAAGCACCA
CCGGCCTCCCATTAACAGCCTGCCCGGGCTCCGCCCACAGGAGCCACTGTCCACGTAACCTGCGTCTCTTTCTTTC
AAGGAAAAGAGAAGCCAGCCATGGCCAGGACCAGCAGCAGGGCCCCCTGCTCACCCACCTCGGTGTCGGATGTG
GACTCGGACGCACTGTCACGGGGAAACTTCGAGGTGGGGTTTCGGCCTCAGAGGTCCGTAAAAGCCGAGAGAGC
GCAGCAGCCTGAGGCTGGCGAGGACAGACGGCCAGCTGGCGGGGCCTCAGACGTGGAGGCAGTGACCCGACTGG
CCAGGTCCAAAGGGGTCGGCCCAGCCTTGTCCCCCGGCCCAGCCGGATTCCAGAGCTGCAGCCCCGGCTGGTGC
AGCGCCTTCTACGAGGCCGACTGCTTCGGGGCCGACGTCCACAACTACGTGAAGGACCTGGGGCGGCAGCAGGC
GGACGGGGCCCTGCCCGACGCCCAGAGCCCG
20 chr9: 129556229-129557670
CGAATGCAGCATCCCTGCGCTCGGCGCCCTGCTATTGGCCAGAGATGATCTCACCGCCTCCCGGCCTGCGCGCGC
CTGATTGGCCGGTGCGGGGATGCTGCGCTCCGCCGCCGGCGGGGCAGTCCTTCAGGCGGGCTCCGCGAGCGTGT
GTGAGCCTGGGGGAGCGAAGAGCCGACGCGCCTGGCATCTCCCAGGGGGCTCAGGGGGCAGGAGCGCGGAGAC
CCCCGGACAGGGTCTTAACCCCTTCCCGCCAGCCCGAGCCCAGCATCCCCTCCAGCTCCCCTCGGCGTCCCAACC
CCAAGCAAAGCCATCCCCAAAGGATGCTCCGCAGAGAGGCGGGGTCCGGGTCCTCCCCTCCACCCCCTTCCGTTT
AACCCTCTCACCGCCGCGGCGCCGTCCTGCACTGCCCGGCCAGCTGGGCTGGGAGAGACCCGCGCCCCAGGCAT
GTCCAAGCCCACCTAGAGGGCGGGAGGGTGGCGGGCGCTCTGGCCCCAACCCTGGCATCCGAAGCATCCCCCGC
GTTTCCTGCTCCTCACTCAGTCTTCAGATCCCAGTCCGGCGCCCCCGGTACAATGGGGAGCCAGGGTGCCCAGGT
CAGCCGCAAGGGCCAGCGTACCAGGCGGAGGACCGGCAGGACGCCGGAGACCCCATCTCCCAGTCCCCCCTGCC
CCAGCTCTCTCCCTCCTGCGGAGGAGGCAGAAACGGACCGGCATCTACCGCAGCCCAGAGTCCCAGGAGTGGCC
GCCGAACCCTCACCCCGCGGAGCGCCTGGGCGCCCAGAGGTGAGGCTGGGGTGACCCCGCCCCCTCCCCGGGTC
GGCCGGGCCCAGCCCAGCCCGACCCTGCCGGGCGCCGCTGAGCTGCAGCTCCCCGGCTGGCTCTAGGGCCCCGG
GCGGAGCGGCCGGGGGTCCCAGCCCGGCGCGCGTGGCGGGGGCCGAGCCGCCCCCTCACCTGCACCTGCACGAA
GGAGCCGCGGTAGAAGCAGCAGGCGGCGGCCGACAGGGCACTCCACAGGCTGCACCGCTCGGTCATGGTGGGGC
CAGGCTGCCGGGGCCGGGACGGTGTGGGGGGGCGGTGGCCGGCGGGGCAGGGGCGCAGGGACCAACCGGCTAG
GCACCGGCTGCGCGTGCCTCTCAGCGGCGCGATTACCTCATCGCCTTGTCGGGGGAGGAGCGGGGAGGCGGGGC
GGGGAGACCCCACCCTCCAGCCGGCCAGGGGAGGGGAGGGGGCCATTGTTCCTCCCTCCGCCCGCCCCCCGCTC
CCAGCCCCTCGCCCCCCGCCCTCCAGTTCCGCGCGCTCGGGCTGCCTGGAGCTGCGGGCGCGGAGCGGAGGACC
TGCCAAGGAGGGTATTACCGGGGGCAGCGGGATCGGGTGGGGACCCATGGGCCAGCGAGGGGAGGTTCTGCCTC
CCCCACTCGCCGCACCTCTAACAGACCGGGAGCG
21 chrX: 47305347-47306043
CGCCTGCGCGAGTCAGGACGAGCGCTTGCCCCAGATCTTGACGTTTCAGGCGGCCCCTCCTAATCCGGAACACGA
CTCACATTCCGTTGGTCTTGCCTTGACAGACGTGACCCTGACCCAATAAGGGTGGAAGGCTGAGTCCCGCAGAGC
CAATAACGAGAGTCCGAGAGGCGACGGAGGCGGACTCTGTGAGGAAACAAGAAGAGAGGCCCAAGATGGAGACG
GCGGCGGCTGTAGCGGCGTGACAGGTGAGGGCGGGCCCGGGAGGGCTCGGTTTCTGGAGCGGCTGCCGGGCAC
GGGCAGGGAGCCCGGACCGAAAGCTCAGCTCCAGGATGGCTGCGCTTGGGCCCCGGCGTTCCCTGCCCGGAACC
GGAGGAGTGGTTTGACCCGGGGCGAGACCATCGTCGACAGCGGGGGTGGGGTGGGTAACAGGAATAGGCGGGCA
AGGCTGCGGGTGATGGTTTCGCCCGCTGCTAGTGGTGGTGCGCCTGCGCAGAGCCGGAAGCCCTTTGGTAGGCG
GGACCCGACCGAGTGGTGCCGGGATTCCGTCTTAACCCCCGCTAAGGTGTCCAATGACCTTTCCTTACCAACTGC
GGGGAGTGTGTGGAAACGCGGTTCACTCCCCGGTTTCCTTATTCTGGATCAGTGTCTGACCGCCCCCGCCGGGAG
AATGTCAGGATTCTCGCCTCT
TABLE 10
Hypermethylated genes and CGIs in bladder cancer.
Fold
Symbol CGI Change
MEIS1 chr2: 66525936-66527140 4.76
NR2F2 chr15: 94688798-94689034 2.93
SOX21 chr13: 94152191-94153185 2.8
MAB21L1 chr13: 34950554-34951119 2.68
OTX1 chr2: 63134539-63134851 2.67
MGC2752 chr19: 63784504-63785085 2.64
IRX3 chr16: 52873104-52882105 2.63
PAX9 chr14: 36205265-36206099 2.62
FOXC1 chr6: 1549606-1560865 2.5
DLX5 chr7: 96488158-96489487, chr7: 2.45
96489900-96490182
NR4A2 chr2: 156892636-156892878, chr2: 2.45
156893804-156894601
CNTNAP1 chr17: 38089258-38089793 2.35
FOXF2 chr6: 1338049-1339169 2.35
HHEX chr10: 94441310-94441717 2.33
PRKCZ chr1: 2072175-2072389, chr1: 2106293-2106661 2.31
HOXA7 chr7: 27164708-27165039 2.27
MSX2 chr5: 174091287-174092335 2.26
SLC45A4 chr8: 142288380-142288627 2.22
FLJ44006- chr2: 111591678-111597436 2.21
BCL2L11
MAP2K2 chr19: 4059920-4060207 2.2
SHH chr7: 155288454-155292175 2.19
chr13: chr13: 49605587-49606020 2.19
MAD1L1 chr7: 2082894-2083307 2.18
hsa-mir- chr17: 44074360-44075233 2.17
196a-1
NXPH1 chr7: 8449658-8450236 2.17
chr18: chr18: 5186244-5187389 2.12
C10ORF114 chr10: 21828640-21829594 2.1
SIX3 chr2: 45014932-45016562, chr2: 2.08
45013398-45013616
TFAP2A chr6: 10530308-10530634, chr6: 2.08
10498025-10498551
ISL2 chr15: 74414579-74414893, chr15: 2.05
74419318-74422570
VAX2 chr2: 70984709-70985764 2.04
AMZ1 chr7: 2724531-2724783 2.01
CYB561 chr17: 58865386-58865618 1.99
HOXD3 chr2: 176737660-176738187 1.97
SIM1 chr6: 101003802-101004342, chr6: 1.95
101002495-101002783
EFNB2 chr13: 105943410-105943788 1.91
GAD1 chr2: 171384799-171385226 1.91
MSX1 chr4: 4915358-4915735, chr4: 4910534-4911092 1.9
FOXA1 chr14: 37137198-37138958 1.88
HDGFL1 chr6: 22677564-22678684 1.85
chr13: chr13: 49595986-49600287 1.84
chr16: chr16: 87372445-87372706 1.84
EVX1 chr7: 27251165-27252762 1.83
UNG2 chr5: 54554812-54555385 1.83
(CCNO)
ONECUT2 chr18: 53254153-53259851 1.81
HSF2BP chr21: 43902100-43904249 1.8
chr1: chr1: 119350668-119352843 1.8
FOXD3 chr1: 63554983-63563059 1.79
FOXA2 chr20: 22514822-22515055, chr20: 1.77
22510737-22514104, chr20: 22505518-22507240
GRIK2 chr6: 101953488-101953856 1.77
chr2: chr2: 45249374-45251690 1.77
SIX1 chr14: 60178708-60179539 1.76
HOXA9 chr7: 27170441-27172987 1.75
FOXD2 chr1: 47671713-47671985, chr1: 1.73
47682300-47683607, chr1: 47672249-47672972
NKX2-8 chr14: 36122886-36123441 1.72
ZNF274 chr19: 63420090-63420541 1.72
TAF4 chr20: 60061693-60062033 1.71
SIX2 chr2: 45085286-45086054 1.7
chr8: chr8: 145909302-145910517 1.7
PCDH7 chr4: 30330303-30333940 1.69
PITX2 chr4: 111774415-111774953 1.68
TCF7L1 chr2: 85213468-85216104 1.68
chr6: chr6: 10492952-10493478 1.68
SOX7 chr8: 10624024-10624296 1.66
HOXC4 chr12: 52726910-52727810 1.65
PITX1 chr5: 134390992-134393045 1.65
PCDHGA12 chr5: 140790679-140792801 1.64
chr6: chr6: 170422815-170423038 1.64
EPN1 chr19: 60907042-60907388 1.63
DLX6 chr7: 96469320-96469736 1.62
hsa-mir-10b chr2: 176723195-176723460, chr2: 1.62
176720618-176720921
SIM2 chr21: 36990064-36995761 1.61
CACNA2D4 chr12: 1844001-1845219 1.6
HOXA5 chr7: 27149139-27152087 1.6
NCK2 chr2: 105864220-105865009 1.6
OSR1 chr2: 19424445-19425131 1.58
C17orf27 chr17: 75936057-75936582 1.57
(RNF213)
chr6: chr6: 169051743-169052507 1.56
EVX2 chr2: 176652334-176656692 1.53
ZNF503 chr10: 76825135-76839606 1.52
chr5: chr5: 92931996-92934631 1.52
KIAA1303 chr17: 76404186-76404427, chr17: 1.48
76390187-76390410
TABLE 11
Genomic distribution of methylated probes in bladder cancer.
Probe location % on array % in bladder cancer
divergent promoter 2.5 2.4
downstream 3.9 4.0
inside 52.4 52.3
promoter 26.0 25.9
intergenic 15.3 15.3
TABLE 12A
Overview of the CGIs differentientially methylated
between tumor and control urine.
Fold
Symbol CGI Change
HOXA9 chr7: 27170441-27172987 16.53
PENK chr8: 57520681-57521969 14.69
PCDH7 chr4: 30330303-30333940 12.00
KCNA1 chr12: 4888847-4891432 11.89
HLX1 chr1: 219134071-219134808 10.46
POU4F2 chr4: 147778656-147781351, 10.17
chr4: 147777682-147778033
LHX4 chr1: 178464743-178471598 9.79
FOXD2 chr1: 47682300-47683607, 9.67
chr1: 47672249-47672972
LBX1 chr10: 102986025-102986636 9.44
chr11: 115956893-115956940 chr11: 115955870-115957122 9.03
LMX1A chr1: 163590111-163590435 8.86
BHLHB5 chr8: 65662303-65662699, 8.61
chr8: 65661156-65661382
OTX1 chr2: 63134539-63134851 8.22
GAD2 chr10: 26544390-26547440 8.02
EVX2 chr2: 176652334-176656692 8.02
FLJ44006-BCL2L11 chr2: 111591678-111597436 7.89
ONECUT2 chr18: 53254153-53259851 7.75
ZIC1 chr3: 148619591-148620015 7.33
FOXA1 chr14: 37137198-37138958 7.24
DSC3 chr18: 26875488-26877115 7.19
SIM2 chr21: 36990064-36995761 6.78
MEIS1 chr2: 66525936-66527140 6.74
FEZF1 chr7: 121727243-121727884 6.62
ZNF503 chr10: 76825135-76839606 6.57
SLC35F3 chr1: 232106922-232108080 6.34
FEZF2 chr3: 62331811-62332352 6.26
NR4A2 chr2: 156893804-156894601 6.20
EN1 chr2: 119329502-119332035 5.59
PCDH10 chr4: 134291113-134293078 5.53
OSR1 chr2: 19424445-19425131 5.23
ZIC4 chr3: 148591199-148594390 5.00
CBLN1 chr16: 47868915-47869809 4.92
HMX2 chr10: 124891898-124892607 4.89
FOXB1 chr15: 58083428-58085812, 4.76
chr15: 58079172-58079459
chr19: 057648585-057648629 chr19: 57648469-57649057 4.58
DPP10 chr2: 115635208-115637235 4.55
chr7: 032768257-032768301 chr7: 32768010-32768497 4.48
C10orf114 chr10: 21828640-21829594 4.44
FOXD3 chr1: 63554983-63563059 4.39
chr5: 092933638-092933682 chr5: 92931996-92934631 4.25
TCF7L1 chr2: 85213468-85216104 4.21
VAX2 chr2: 70984709-70985764 3.99
CBLN2 chr18: 68359955-68362770 3.97
PCDHGA12 chr5: 140790679-140792801 3.94
chr21: 037857850-037857894 chr21: 37857725-37858416 3.89
HOXA7 chr7: 27164708-27165039 3.79
GRIK2 chr6: 101953488-101953856 3.77
NKX2-8 chr14: 36122886-36123441 3.65
SOX9 chr17: 67627870-67631593 3.64
chr18: 005186349-005186393 chr18: 5186244-5187389 3.50
SOX21 chr13: 94152191-94153185 3.43
SNRPF chr12: 94776152-94776377 3.39
MSC chr8: 72916429-72917309 3.18
PITX1 chr5: 134390992-134393045 3.05
SOX7 chr8: 10624024-10624296 2.99
chr2: 042182832-042182879 chr2: 42182944-42183157 2.97
TBX15 chr1: 119333515-119333719 2.96
SIM1 chr6: 101003802-101004342 2.91
PFKFB1-APEX2 chrX: 55043085-55043710 2.89
GATA2 chr3: 129688183-129694961 2.86
chr5: 122462228-122462286 chr5: 122461778-122463450 2.82
GPR103 chr4: 122521018-122521740 2.81
SIX2 chr2: 45085286-45086054 2.80
SFMBT2 chr10: 7489383-7495345 2.79
NXPH1 chr7: 8449658-8450236 2.73
CA10 chr17: 47590175-47591465 2.71
CNTNAP5 chr2: 124498723-124499725 2.66
ZNF274 chr19: 63420090-63420541 2.62
HOXD3 chr2: 176737660-176738187 2.61
PITX2 chr4: 111774415-111774953 2.55
OLIG2 chr21: 33316999-33322115 2.54
FOXA2 chr20: 22505518-22507240, 2.53
chr20: 22510737-22514104
DBC1 chr9: 121170908-121172035 2.49
PAX2 chr10: 102497473-102499636 2.45
MAB21L1 chr13: 34950554-34951119 2.35
CYP26B1 chr2: 72224630-72228512 2.31
CBLN4 chr20: 54012011-54014085 2.26
GAD1 chr2: 171384799-171385226 2.25
HHEX chr10: 94441310-94441717 2.22
chr9: 013268499-013268548 chr9: 13268313-13269805 2.20
FOXF2 chr6: 1338049-1339169 2.17
DLX5 chr7: 96489900-96490182 2.08
TBX3 chr12: 113589232-113589931 2.04
MEIS2 chr15: 35174679-35174906 2.04
PTGER3 chr1: 71284813-71286392 2.04
TABLE 12B
Overview of CGIs associated with progression of NMI-BC.
Symbol CGI FC
GPR103 chr4: 122520930-122520974 1.81
chr2: 042182832-042182879 chr2: 042182832-042182879 1.96
KCNA1 chr12: 004890074-004890118 2.01
HLX1 chr1: 219134113-219134157 2.14
DBC1 chr9: 121171898-121171944 2.59
GPR103 chr4: 122521031-122521075 4.17
TBX3 chr12: 113609259-113609303 2.76
GATA2 chr3: 129693434-129693486 2.20
TBX2 chr17: 056833879-056833928 2.15
TBX2 chr17: 056835246-056835290 2.10
ZNF577 chr19: 057082979-057083023 2.08
MSC chr8: 072916695-072916739 1.82
EXAMPLES Example 1 The CpG island hypermethylations as indicated in the Tables 1-5 are the result of comparative studies using well characterized patient samples. Both tumor samples and controls were analyzed. The DNA was extracted directly from the tumor and control tissue. DNA samples were analyzed using a CpG island microarray comprising 200.000 CpG islands (Agilent Technologies Inc.). The results obtained are indicated in the various Tables 1-5 as listed herein.
Example 2 Materials & Methods Patient samples, ethics statement and DNA isolation Samples from 44 fresh frozen bladder cancer tissues were collected, representing 29 non-muscle invasive tumors (19 with FGFR3 mutation (NMI-mt) and 10 without (NMI-wt)) and 15 muscle-invasive tumors (MI). Tumor tissue of patients was obtained from the Department of Urology of the Erasmus MC, Rotterdam. The medical-ethical committee of the Erasmus MC Rotterdam approved the project. All patients gave written informed consent. For validation, 90 formalin-fixed, paraffin-embedded (FFPE) bladder cancer samples (27 Ta NMI-mt, 13 Ta NMI-wt, 10 T1-mt, 14 T1-wt, 26 MI) were collected from the Department of Pathology. Usage of these samples was performed according to standards presented in “The Code for Proper Secondary Use of Human Tissues in The Netherlands” (http://www.federa.org). Tumor samples were included only if at least 80% of the sample consisted of cancer cells, as verified by H&E staining. DNA from tumor tissue was isolated with the DNeasy Tissue kit (Qiagen, Hilden, Germany), according to the instructions of the manufacturer. Commercially available normal human genomic blood DNA (Promega, Madison, Wis., USA) was used as a reference in the genome wide analysis and the GGMA. DNA isolated from cells present in normal urine of four healthy persons of more than 50 years old was used as reference DNA in the GGMA validation assay.
Differential Methylation Hybridization (DMH) and Data Analysis DNA amplicons were prepared for hybridization according to the DMH (differential methylation hybridization) protocol described by Yan et al [Yan et al. 2002.) Methods Mol Biot 200: 87-100]. Briefly, 0.5 μg of genomic DNA was digested with the four base (T̂TAA) restriction enzyme MseI, which restricted genomic DNA into fragments less than 250 bp in length, while leaving the GC-rich CGIs relatively intact. Subsequently, the sticky ends of the fragments were ligated to linker primers. Samples were then digested with the methylation-sensitive restriction enzymes HpaII and BstUI to increase the genome coverage and to ensure complete digestion. Reference samples were treated in the same way to generate amplicons. PCR reactions (20 cycles) were performed using the purified, digested, linker ligated DNA as template to generate final target amplicons, followed by coupling to fluorescent dyes (Cy3 in case of human genomic reference DNA and Cy5 in case of tumor samples) before hybridizing to the Agilent 244K CpG island microarray. The pooled amplicons were co-hybridized on the array. Using this approach, genomic DNA fragments containing unmethylated CpG sites in one sample (e.g. the human genomic reference DNA) were degraded by restriction digestion and not amplified. However, corresponding DNA fragments in the other sample (the bladder tumor) that contain methylated restriction sites were protected from digestion and subsequently amplified by PCR. Differentially methylated sequences were identified by comparing hybridization signals between fluorescently labeled tumor (Cy5) and reference (Cy3) amplicons.
All microarray data generated are compliant with current MIAME standards according to Brazma et al [Brazma 2009. Scientific World J 9:420; Brazma et al. 2001. Nat Genet 29:365]. Normalization, preprocessing of raw data and statistical analysis were done using Bioconductor packages in an R programming environment (http://www.r-project.org/). Raw hybridization signals were normalized by applying the within-array global “lowess” normalization method [Yang et al. 2002. Nucleic Acids Res 30: e15], which assumes that the bulk of the probes on the array are not differentially expressed. The normalization also includes a pre-processing step, as a result of which the normalized intensities were log 2-transformed. The log2-transformed intensities were then subjected to further statistical testing to determine which loci were differentially methylated. The linear model “limma” was applied [Smyth 2004. Stat Appl Genet Mol Biol 3: Article3]. We performed the following comparisons: All tumors vs. Blood, NMI-mt vs. NMI-wt, NMI-mt vs. MI, and NMI-wt vs. MI, to find genes that have different methylation profiles across the groups compared. These comparisons are analogous to a classical two sample t-test analysis.
The p-value threshold was calculated using the Benjamini and Hochberg method [Benjamini et al. 2001. Behav Brain Res 125: 279]. The loci corresponding to p-values less than 0.05 and a log fold change of either greater than 0.5 or less than −0.5 with more than 2 probes representing the same CGI were classified as differentially methylated. We left chromosome Y probes out of the subsequent analyses.
Illumina Custom Golden Gate Methylation Assay and Statistical Analysis We designed a custom Golden Gate Methylation assay interrogating 384 CpG containing probes representing 238 CGIs, 184 genes, and 46 intergenic regions. The selection of the probes was based on the differentially methylated loci in the genome-wide analysis. Probes were included to detect methylation in all bladder subgroups, but also probes that appeared to be specific for a certain subgroup compared to others, and some probes specific for progression or death of disease. The methylation assay is an adaptation from the Illumina high-throughput SNP genotyping assay described by Fan et al. [Fan et al. 2003. Cold Spring Harb Symp Quant Biol 68: 69]. In short, non-methylated cytosines (C) were converted to uracil (U) by treatment with bisulfite. Sodium bisulfite modification of genomic DNA was carried out using the EZ DNA Methylation Gold Kit (Zymo Research Corp, Orange, Calif., USA) according to the manufacturer's protocol, using 0.8 μg of FFPE DNA. The conversion efficiency was monitored by PCR with universal BS specific primers provided with the kit. Arrays were run at Service XS, Leiden, the Netherlands according to the manufacturer's protocol and as described by Bibikova et al. [Bibikova et al. 2006. Genome Res 16: 383].
Data were analyzed with Illumina's BeadStudio Methylation module software. All array data points were represented by fluorescent signals from both methylated (M) and unmethylated (U) alleles. The average methylation value β was derived from approximately 30 replicate methylation measurements for each locus. The methylation level was given by β=(max(M, 0))/(|U|+|M|+100). The β-value (0≦β≦1) reflects the methylation level of each CpG site where 1 represents fully methylated and 0 represents unmethylated. At each locus for each sample, the detection p-value was defined as 1−p-value computed from the background model characterizing the chance that the signal was distinguishable from negative controls. Using this as a metric for quality control for sample performance, 6 FFPE samples (6%) were dropped from the analysis, because they either had very low overall signal intensities or >25% of loci failed. The significant differences were assessed by comparing the average β value per locus per group. Significant loci were selected on the basis of an average β value ratio larger than 1.4 and a difference between the average β value (Δβ) larger than 0.3.
Validation of Methylation of Individual CGIs We used the MS-SNAPSHOT method described in [Gonzalgo and Liang 2007. Nat Protoc 2: 1931; Lurkin et al. 2010. PLoS One 5: e8802] to investigate methylation in urine DNA quantitatively. The method involves the bisulfite conversion of genomic DNA and the subsequent amplification of interested genomic region. This is followed by the methylation specific single nucleotide primer extension with CpG specific probes and finally the fragments are visualized on a ABI sequencer. To test the method, methylation of MEIS1 gene was investigated using normal, patient urine samples along with bladder cancer cell lines. In vitro methylated DNA was used as a positive control. A list of primers and probes used is given in Table 6.
Results A genome wide methylation profile for bladder cancer
To investigate global DNA methylation in bladder cancers, we analyzed 44 bladder tumors on Agilent 244K human CpG island microarrays using differential methylation hybridization. We found that 729 different probes were significantly more methylated in bladder tumors compared to blood with a log fold change greater than 0.5 and a p value of <0.05. To select the most hypermethylated CGIs, we used as an additional criterion that 3 or more CpG dinucleotides should be highly methylated in a specific CGI. This selection generated a list of 82 CGIs representing 71 genes and 11 CGIs not directly associated with a gene according to the Agilent information file. These are shown in Table 10. The gene showing the highest degree of methylation was MEIS1 with a log fold change of 4.8 for the most highly methylated probe and an average log fold change of 2.2 across the 10 probes that were present on the array for this CGI (FIG. 1). We observed that for most of the significantly methylated CGIs, the adjacent CpG dinucleotides within a CGI were co-methylated. In contrast, CGIs neighboring a methylated island were usually not methylated.
Methylation of Intronic CGIs is Associated with Reduced Gene Expression
The 244k array contains probes for CGIs as displayed in the UCSC genome browser (http://genome.ucsc.edu/cgi-bin/, build 19). Of the CGIs represented on the array, 26% is located in promoter regions. Many studies have shown that aberrant methylation of CGIs in promoter regions represents one of the most frequent epigenetic events associated with gene silencing in cancer. In our analysis we observed that there was no specific preference for methylation of promoter regions. Instead, methylation was distributed proportionally over CGIs in promoter regions, within genes and in intergenic regions (Table 11). Examples are shown for CGIs in two of the selected genes, MEIS1 and NR4A2 (FIG. 1). To investigate whether methylation outside promoter regions also repressed gene expression, we next compared genes with methylated CGIs with available genome-wide expression profiles of bladder cancer using the Oncomine database [Blayeri et al. 2005. Clin Cancer Res 11: 4044; Dyrskjot et al. 2004. Cancer Res 64: 4040; Dyrskjot et al. 2003. Nat Genet 33: 90; Lindgren et al. 2006. Oncogene 25: 2685; Modlich et al. 2004. Clin Cancer Res 10: 3410; Sanchez-Carbayo et al. 2006. J Clin Oncol 24: 778]. This information could be obtained for 54 genes. Out of these 54 genes, 22 showed promoter CGI methylation and a positive correlation with low expression was observed in 17 genes (77.3%). The remaining 32 genes showed methylation of CGIs within introns. Interestingly, 23 of these genes also showed low expression (71.9%) in bladder cancers. These data suggest that not only promoter CGI methylation but also methylation of intronic CGIs leads to reduced gene expression. The expression profile box plots of MEIS1, NR4A2 and HOXA9 are shown in FIG. 1.
Analysis of Individual Subgroups Shows NMI-wt Tumors to have a Highly Methylated Profile
To explore whether global DNA methylation can identify subgroups of bladder cancer, we performed an unsupervised analysis by means of a principal component analysis (PCA) using all probes on the array (244K) (FIG. 2A). The first three components of the PCA explained 42.4% of the variability between the samples suggesting that there is a reasonable discrimination between the subgroups. This unsupervised analysis indicates the presence of two clusters of bladder cancer patients. The NMI-wt tumors (in green) clustered closely together and separate from the NMI-mt (in blue) and MI tumors (in red). Furthermore, we looked at the individual subgroups of bladder tumors. NMI-wt tumors showed a 2.7 to 4.6 times higher number of hypermethylated probes compared to the NMI-mt and MI groups (FIG. 2B). A list of genes differentially methylated between subgroups is given in Table 12.
We next clustered the different subgroups of bladder tumors based on all probes that were differentially methylated between two groups with a p value of <0.05, regardless of the log fold change. For clustering of probes differing between NMI-mt and MI tumors, we had to use a p-value<0.5 because not many differences exist between these two groups. We employed a hierarchical clustering algorithm choosing Euclidian distance and complete linkage to organize the three different comparisons (FIG. 3). We then performed principal component analysis on the same data. The probes along with gene names and p-values are listed in Table 12. These semi-supervised analyses showed clearly that the different bladder cancer subgroups can be identified based on their methylation pattern.
Genes Hypermethylated in Bladder Cancer Often are PcG Target Genes Polycomb group (PcG) proteins function as transcriptional repressors of genes that have been implicated in stem cell self renewal and differentiation. These PcG target genes have been shown to be particularly prone to DNA methylation in cancers [Ohm et al. 2007. Nat Genet 39: 237; Widschwendter Met al. 2007. Nat Genet 39: 157; Schlesinger et al. 2007. Nat Genet 39: 232]. We investigated whether DNA hypermethylation in bladder cancer was more present in PcG target genes by matching our list of 71 genes from Table 10 with recent studies showing that 8-14% of all genes in the genome to be PcG regulated [Bracken et al. 2006. Genes Dev 20: 1123; Lee et al. 2006. Cell 125: 301]. Notably, we found that 63.3% of the hypermethylated genes in bladder cancer were PcG target genes, with a representation factor of more than 3 (http://elegans.uky.edu/MA/progs/representation.stats.html) (FIG. 4A). This was approximately the same for all different tumor subsets. Twenty-two PcG regulated genes were methylated in all three subtypes, while a striking 81 genes were specific to NMI-wt tumors (FIG. 4B). A list of the PcG target genes methylated in bladder cancer is given in Table 8.
Genes Methylated in Blood Compared to Bladder Cancer We also observed 21 CGIs that were methylated in blood but not in bladder tumors. These are listed in Table 9. We compared our results with a study based on methylated DNA immunoprecipitation (MeDIP), in which the genome-wide methylation pattern in blood was investigated [Rakyan et al. 2008. Genome Res 18: 1518]. We found a 90% correlation with their study.
Validation of Hypermethylation and Markers for Diagnosis and Progression Next we set out to validate the selected significant CGIs on a custom Illumina platform based on bisulfite conversion of tumor DNA. The following CGIs were included in the custom array:
1) Differential methylation between tumors and blood (Tables 9 and 10);
2) Probes that could be of use as biomarkers to distinguish the subgroups. There were 7 CGIs representing 6 genes found to differentiate between NMI-mt and NMI-wt tumors. In the MI versus NMI-wt comparison, we found 17 CGIs representing 13 genes to be significant. No significant probes were found between the MI versus NMI-mt subgroups at a p-value<0.05. Therefore we decided to include probes from 6 CGIs representing 6 genes with a p-value<0.5;
3) CGIs that were associated with progression and survival. In all cases the CGI to be validated had at least 3 CpGs that were highly methylated.
We employed a hierarchical clustering algorithm on the average beta values per subgroup with all 384 probes on the array choosing Euclidian distance and complete linkage. The analysis clearly separated the bladder tumors from normal urine and blood (FIG. 5A). We were able to validate more than 70% of the probes hypermethylated in all bladder tumors. For example, in the custom 384-plex GGMA, there were 205 probes which were methylated in bladder cancer but not in blood based on our Agilent array data. Of these, 147 probes were also methylated in bladder cancer but not in blood in the GGMA. These probes are shown in the heat map (FIG. 5B). We also included DNA isolated from cells present in urine of healthy individuals, which most likely are derived from normal urothelial cells. Eighty % of the probes validated against blood were also not methylated in urine. For the different subgroups of bladder tumors, the number of probes validated varied between 65-75% of probes compared to blood and 76-83% compared to urine.
CGIs that are differentially methylated between tumors and urine from non-bladder cancer controls represent potential biomarkers for urine tests (Table 12). We validated several of these using a bisulfite specific PCR followed by a Snapshot assay for the CpG. The results of these analyses are shown in FIG. 5C. We were able to detect methylation in urine DNA quantitatively using this method. We investigated MEIS1 gene methylation at two CpG sites using different probes (MEIS1 A and B). The black peak (Cytosine) represents methylation and red peak (Thymine) represents no methylation. In vitro-methylated DNA (IM), BC patient urine sample (PU) and bladder cancer cell lines (RT112, T24, J82) showed a strong methylation signal while normal urine (NU) and blood DNA (NB) were not methylated.
Next we analyzed the CGIs that were included on the GGMA as potential markers for progression. To this end the 6 best CGIs that were methylated in non-progressors vs progressors and similarly, 6 CGIs that were methylated in progressors vs. non-progressors were analyzed separately and in several combinations (Table 12B). The Kaplan-Meier curves depicted in FIG. 5D show that a combination of CGIs in the GPR103, DBC1 and GATA2 genes can significantly predict progression (p=0.001). Interestingly, methylation of the GPR103 and DBC1 CGIs was inversely correlated with progression and methylation of GATA2 was strongly indicative for progression. The DBC1 associated CGI overlaps with the promoter of this gene, whereas the GATA2 and GPR103 CGIs are located in introns.
Discussion We report an investigation of bladder cancer-associated aberrant DNA methylation. To our knowledge this is the first study that addresses genome-wide methylation in bladder cancer. The major goal of this work was the identification and validation of methylated CGIs that could serve as biomarkers for the early detection of primary and recurrent tumors as well as markers that are predictive of disease course. The genome-wide screen resulted in the selection of 177 CGIs that significantly differed in methylation in tumors when compared to blood. About 70% of these CGIs could be validated in a custom GGMA assay. This analysis also showed that most of these CGIs were not methylated in urine-derived DNA from age matched non-bladder cancer controls. This group of CGIs represents markers for urine based assays. Methylation of some of these markers was confirmed on urine samples. Another important finding is that a combination of CGIs from the GRP103, DBC1 and GATA2 genes is able to predict progression to muscle-invasive disease. Loss of heterozygosity or homozygous deletions of DBC1 (also called DBCCR1) gene (deleted in bladder cancer 1) have been observed in many bladder tumors, as well as methylation of the promoter. Methylation has so far not been correlated to disease course. In our study methylation of the promoter CGI of the DBC1 gene was associated with a decreased risk of progression. The role of the GATA 2 transcription factor in cancer is contradictory. Decreased expression was found to be correlated with proliferation in monocyte progenitors, whereas high expression seems to poise prostate cancers for a more aggressive phenotype and gain-of-function point mutations have been found in chronic myeloid leukemia. In bladder tumors a lower expression of this protein has been observed in MI vs. NMI-BC, which correlates with methylation and the positive association with progression. The GPR103 (QRFPR) gene encodes a G protein-coupled receptor and hence the protein is involved in signal transduction, however, but no further data about the gene or its product can be found in the literature.
Most genes discovered in the present study have never been shown to be methylated in bladder cancer or in other types of cancer. Some of the previously described methylated CGIs in bladder cancer that are associated with the SOX9, CDKN2A, TERT, DAPK1, EDNRB, and LAMB3 genes were also found to be methylated in our study, although only SOX9 and CDKN2A made it to the list of our 177 highly methylated CGIs.
To our surprise we observed that NMI-BCs with a wild-type FGFR3 gene have more methylated CGIs and the intensity of methylation is more profound than in the FGFR3 mutant NMI-BC and MI-BC groups. The difference in methylation presents additional evidence that the two subgroups of NMI-BC develop along different pathogenesis pathways. WT NMI-BCs also have more wide spread chromosomal aberrations than FGFR3 MT NMI-BCs. The extensive methylation in WT NMI-BC is reminiscent of the CpG island methylator phenotype (CIMP) that characterizes a subset of colorectal cancers (CRC). CIMP in CRC also identifies a subset of CRCs as it is associated with BRAF mutations, microsatellite instability and occurs more often in elderly females. No large-scale genome-wide study on DNA methylation has been performed for CRC, however, CIMP has been studied using a 1536-plex GGMA array.
When comparing the genes methylated in this study with those found by us, there was hardly any overlap. This confirms that CGI methylation is tissue and tumor type specific.
In line with previous reports in solid tumors, a high proportion of the genes we find de novo methylated in bladder cancer are repressed by polycomb complexes (PcG) in embryonic stem cells. PcG target genes are as much as 12 times as likely to be silenced by DNA methylation in cancer as non-PcG target genes. The association between DNA methylation and PcG has further been substantiated by the finding of interactions between DNMT1, DNMT3A, DNMT3B and several PcG complex subunits like EZH2 and BMI1. Another recent study showed that 49% of the genes methylated in colon cancer are polycomb targets in embryonic stem cells, agreeing with other reports showing that genes prone to tumor specific hypermethylation in colon cancer were more likely to be marked by H3K27 methylation in normal tissues than genes lacking H3K27 methylation. Another study reported that many genes hypermethylated in a prostate cancer cell line were bound by PcG in normal cells but lost PcG binding upon acquiring DNA methylation in cancer. In this perspective we found that 60% of the hypermethylated genes in bladder cancer are PcG targets in embryonic stem cells. These epigenetic alterations occurring in early development specifically in stem or progenitor cells might be bladder cancer specific and this strengthens the further understanding of bladder cancer tumorigenesis. Besides finding 92 commonly PcG regulated genes in bladder cancer subgroups, a group of 336 genes regulated by PcG complexes are found to be specific to NMI-wt tumors. Besides a possible CIMP phenotype being the cause for the extensive methylation in this group, another possible explanation for this finding could be that the cell from which the WT NMI-BCs originate is more closely related to the embryonic or bladder stem cell than the founder cells of the MT NMI and MI-BCs. In general it is thought that lineage-specific genes are activated during subsequent differentiation steps and during this process the PcG complexes will be replaced by cell fate specific transcription factors. Hence, fewer possible methylation targets will remain after every differentiation step.
Our data clearly shows that adjacent loci within a certain CGI are co-methylated, while neighbouring CGIs of a certain gene can have a very different methylation level. Significant association among the methylation states of adjacent CpG sites and a high frequency of short-range co-methylation was reported previously. Another interesting finding in this study is that our data shows no preference for methylation of CGIs in promoter regions compared to gene bodies, since the location of the significant CGIs is distributed over the genome in accordance to the distribution of CGIs on the array. The effects of promoter methylation on chromatin organization and gene expression have been well documented in various types of cancer. In our study, besides promoter methylation, we found more than 50% of all significant probes to be located in CGIs located within gene bodies. The influence of this on gene expression in not fully known. Previous reports in Arabidopsis have shown that gene body methylation was low in genes transcribed at low levels, higher in highly transcribed genes, and absent in genes that were not transcribed. By comparing our methylation results with gene expression studies, we show that for 70% of our genes there is an inverse correlation with gene expression, suggesting that intragenic methylation also contributes to gene silencing.
In summary we have identified hypermethylated CGIs in bladder cancer. The aberrant DNA methylation in bladder cancer seems to be very selective and could be the first step in tumor initiation, especially for the WT NMI-BCs. The study also illustrates an interesting biological finding: besides the promoter methylation intragenic methylation observed to the same extent in bladder cancer and it also appear to influence the gene expression. Many discovered methylated CGIs represent putative biomarkers for early detection in urine-based assays. The combination of CGIs from the GRP103, DBC1 and GATA2 genes predicts progression to muscle-invasive disease. Thus, the CGIs identified in this study will be of considerable interest for further investigation of their clinical and functional relevance and will provide advance insights into the pathogenesis of bladder cancer.
