Abstract: Porous bodies are produced which are suitable for use as supports for catalysts, including living cells, such as bacteria and which are upset resistant to acids and bases. The bodies have a significantly large average pore diameter of about 0.5 to 100 microns, (i.e. 5,000 to 1,000,000 .ANG.) and a total pore volume of about 0.1 to 1.5 cc/g with the large pores contributing a pore volume of from about 0.1 to 1.0 cc/g. The bodies are made by preparing a mixture of ultimate particles containing a zeolite and one or more optional ingredients such as inorganic binders, extrusion or forming aids, burnout agents, or a forming liquid, such as water. In a preferred embodiment, the ultimate particles are formed by spray drying.

Abstract: A supported catalyst comprising a carbon fibril aggregate and a catalytically effective amount of a catalyst supported therein, a process for performing a catalytic reaction in fluid phase using the supported catalyst and a process for making the supported catalyst are disclosed.

Abstract: Multimetal oxide compositions having a two-phase structure and comprising molybdenum, hydrogen, one or more of the elements phosphorus, arsenic, boron, germanium and silicon, and copper, and their use for the preparation of methacrylic acid by gas-phase catalytic oxidation.

Abstract: In accordance with the present invention there is provided a system and method for featuring information on a record. The system and method utilize reactant and coreactant compositions which are formulated to produce a color-changing reaction when brought together. The system and method also utilize a record having first and second areas disposed adjacent to each other. The second area is generally treated with the reactant composition. The coreactant composition is formulated to exhibit a first marking color on the first area of the record and to produce a color-changing reaction with the reactant composition on the second area of the record. The color-changing reaction effects a second marking color on the second area. The system and method further utilize a writing implement containing the coreactant composition. The implement is used to deposit the coreactant composition on the first and second areas in the form of symbolic information.

Abstract: A roll-type heat transfer image-receiving sheet comprising a wind-up cylinder and a heat transfer image-receiving sheet which comprises at least a substrate and a coloring material-receiving layer provided thereon, the heat transfer image-receiving sheet being wound around the wind-up cylinder, wherein the maximum surface roughness of the wind-up cylinder in the longitudinal direction thereof is controlled to 40 micrometers or less; the wind-up cylinder is prepared by using pulp as a main component, and a cushioning material is provided between the wind-up cylinder and the heat transfer image-receiving sheet; a lead sheet is provided to the leading end of the heat transfer image-receiving sheet so that the image-receiving sheet can be easily led through a printer; and the heat transfer image-receiving sheet is wound around the wind-up cylinder with the coloring material-receiving sheet outside so that curl will not remain in the image-receiving sheet and that curl will not be developed during a printing proce

Abstract: A dry flowable agricultural composition made by mixing glyphosate and an anhydrous base salt with a sulfonylurea herbicide and stabilizer (sodium metasilicate or sodium carbonate), all of which is combined a heat activated binder without using a drying step.

Abstract: Cyclic acetals of the formula I ##STR1## where the substituents have the following meanings: R.sup.1 and R.sup.2 are hydrogen, unsubstituted or substituted alkyl or phenyl; additionally R.sup.1 and R.sup.2 together are an unsubstituted or substituted C.sub.2 -C.sub.6 -alkylene chain;Y is oxygen or sulfur;A has the meaning as given in claim 1;a process for preparing the acetals I and their use for the production of crop protection compositions are described.

Abstract: Two-powder processes for the synthesis of superconducting (Bi, Pb)-2223/Ag-clad wires by the oxide-powder-in-the-robe are provided. The first precursor powder, of nominal stoichiometry CaCuO.sub.x, is a solution-synthesized mixture of Ca.sub.0.45 Cu.sub.0.55 O.sub.2 and CaO. Using these oxide precursor mixtures, superconducting tapes with well-aligned grains and reproducible critical current densities J.sub.c in the range of 20,000 to 26,000 A/cm.sup.2 at 75 K in self-field after annealing less than 200 hours were obtained.

Abstract: An environmentally friendly invert drilling fluid comprises a water-in-oil emulsion which includes (a) at least 50 volume percent of a low toxicity base oil, and (b) at least one additive selected from the group consisting of emulsifiers, viscosifiers, weighing agents, oil wetting agents and fluid loss preventing agents, at least about 25 weight percent of the base oil content of the drilling fluid being a mixture of a linear alkane combined with a branched chain alkane, the alkanes individually having from about 14 to about 30 carbon atoms.

Abstract: A grease composition for a constant velocity joint contains a base oil containing 2 to 25 wt. % of a thickener based on total weight of the composition, 0.5 to 20 wt. % of boron nitride powders based on total weight of the composition, and 0.1 to 10 wt. % of an extreme pressure agent based on total weight of the composition selected from the group consisting of molybdenum dithiocarbamate, a sulfur and phosphorus-containing extreme pressure agent, and mixtures thereof. The boron nitride powders have mean particle size of more than 5 .mu.m and not more tha 20 .mu.m.

Abstract: This invention relates to a composition, comprising: (A) an acylated amine having a base number in the range of about 45 to about 90, said acylated amine being the product made by contacting (A)(I) at least one carboxylic acid acylating agent with (A)(II) at least one polyamine, said polyamine (A)(II) being selected from the group consisting of (A)(II)(a) a product made by contacting at least one hydroxy material with at least one amine, (A)(II)(b) an alkylene polyamine bottoms product, and (A)(II)(c) a product made by contacting a hydroxy material with an alkylene polyamine bottoms product; (B) a boron compound; and (C) an organic phosphorus acid or ester, or derivative of said phosphorus acid or ester. In one embodiment, this composition further comprises (D) a thiocarbamate. In one embodiment, this composition further comprises (E) a nitrogen-containing ester of a carboxy-containing interpolymer.

Abstract: A low dosage, highly dense detergent product is provided. The detergent composition comprises: (a) from about 40% to about 80% by weight of spray dried detergent granules; (b) from about 20% to about 60% by weight of detergent agglomerates having a density of at least about 700 g/l; and (c) from about 1% to about 20% by weight of adjunct ingredients. The weight ratio of the granules to the agglomerates is from about 3:1 to about 1:3 and the composition has a density of at least about 650 g/l.

Abstract: A polypeptide compound having antifungal activities of the following general formula: ##STR1## wherein R.sup.1 is hydrogen R.sup.2 is acyl group,R.sup.3 is hydroxy or acyloxy,R.sup.4 is hydroxy or hydroxysulfonyloxy,R.sup.4 is hydrogen or lower alkyl which may have one or more suitable substituent(s), andR.sup.6 is hydrogen, hydroxy or acyl (lower) alkylthio and a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a compound selected from those of formula (I) (SEQ ID NO:1): ##STR1## in which R.sub.1, R.sub.2, X.sub.1 and X.sub.2 are as defined in the description, useful as inhibitor of the proliferation component of vascular smooth muscle cells.

Abstract: The invention features a method of using insulin-like growth factor-I (IGF-I) or insulin-like growth factor-III (IGF-III) to prevent or treat peripheral neuropathy in a mammal.

Abstract: A method of treating inflammation in a subject by administering a therapeutically effective amount of a compound having the structure: ##STR1## where R.sub.1 to R.sub.4 are the same or different and are each selected from the group consisting of H, an alkylacyl group, an arylacyl group, or a C-1-linked saccharide.

Abstract: This invention provides a compound having the structure: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are same or different, and are hydrogen, hydroxyl, or fluorine; Z is O, CH.sub.2 or CF.sub.2 ; R is chlorine, bromine, iodine, carbonitrile, carboxylic ester, or carboxamide; and one of W, X and Y is N or N.sup.+ R', wherein R' is methyl or ethyl, and all others are CH; provided that R.sup.1 is not H when R.sup.2 and R.sup.3 are OH, Z is O, R is carboxamide and W is N or N.sup.+ R'.This invention also provides methods of preparing the compounds and a method of treating a mammal having a NAD-dependent enzyme associated disorder.

Abstract: A topical anti-acne treatment which comprises salicylic acid and lactic acid, adjusted to a selected pH and placed in a suitable vehicle, such disclosed formulations can be used by individuals with adult acne, rosacea and sensitive skin complicated with acne.

Abstract: Dihydrospirorenone, ##STR1## preferably together with an estrogen, can be used for the production of a pharmaceutical agent suitable for treatment of hormonal irregularities during premenopause (menstruation stabilization), for hormonal substitution therapy during menopause, for treatment of androgen-induced disorders and/or for contraception.

Abstract: Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

Abstract: Compounds of general formula (I) ##STR1## and physiologically acceptable salts thereof; wherein R.sub.1 represents CH.sub.2 CONR.sub.5 R.sub.6 or CH.sub.2 COR.sub.7 ;R.sub.2 represents a phenyl group optionally substituted by 1 or 2 substituents selected from halogen, alkyl, nitro, cyano, trifluoromethyl, trifluoromethoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, amino, substituted amino, hydroxy, alkoxy, methylenedioxy, alkoxycarbonyl, oxazolyl or oxadiazolyl;A represents a C.sub.1-4 straight or branched alkylene chain;R.sub.3 and R.sub.4 independently represent hydrogen or C.sub.1-4 alkyl or R.sub.3 and R.sub.4 together with the nitrogen atom to which they are attached form a saturated 5-7 membered heterocyclic ring, which ring may contain an additional heteroatom selected from oxygen, sulphur or nitrogen;R.sub.5 represents hydrogen or C.sub.1-4 alkyl;R.sub.6 represents C.sub.1-4 alkyl or phenyl, optionally substituted by halogen, or R.sub.5 and R.sub.

Abstract: Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.

Abstract: A novel fungicidal composition comprising a fungicidally effective amount of a combination consisting of(A) the known aminomethyl heterocycle of: the ##STR1## and (B) at least one other known fungicidally active compound selected from the group mentioned in the specification.The novel compositions show a synergistic activity.

Abstract: The compound (-)-[[4-(1,4,5,6 tetrahydro-4-methyl-6-oxo-3 pyridazinyl) phenyl]-hydrazono] propane dinitrile and its salts are prepared and used for treating congestive heart failure.

Abstract: The invention concerns tricyclic derivatives of the formula I ##STR1## wherein R.sup.1 and R.sup.2 together form an optionally substituted group of the formula --N.dbd.CH--NH--, --N.dbd.CH--O--, --N.dbd.CH--S--, --N.dbd.N--NH--, --NH--N.dbd.CH--, --NH--CH.dbd.CH--. --NH--CO--NH--, --NH--CO--O--, --NH--CO--S--, --NH--NH--CO--, --N.dbd.CH--CH.dbd.N--, --N.dbd.N--CH.dbd.CH--, --N.dbd.CH--N.dbd.CH--, --N.dbd.CH--CH.dbd.N--, --NH--CO--CH.dbd.CH-- or --N.dbd.CH--CO--NH--; m is 1, 2 or 3 and R.sup.3 includes hydrogen, halogeno and (1-4C)alkyl; or a pharmaceutically-acceptable salt thereof;processes for their preparation; pharmaceutical compositions containing them; and the use of the receptor tyrosine kinase inhibitory properties of the compounds. in the treatment of cancer.

Abstract: Compounds of the general formula I: ##STR1## are disclosed as novel antipsychotic agents.

Abstract: 3-(2,2-Dimethyl-propyl)-pyridine is used to impart, improve or modify the odor properties of a variety of consumer products. In particular, it develops fruity-fresh type notes.

Abstract: A new process for the production of .beta.-carbolines by dehydrogenation of tetrahydro-.beta.-carbolines with trichloroisocyanuric acid is described.

Abstract: Compounds useful in the treatment of inflammatory disorders, central nervous system disorders and other disorders of formula (I) and the pharmaceutically-acceptable salts thereof, wherein X.sup.1 is alkoxy or halosubstituted alkoxy; X.sup.2 is hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, halosubstitued alkyl, halosubstituted alkoxy, alkylamino, dialkylamino, alkylsulfonylamino (which may be substituted), N-alkyl-N-alkylsulfonylamino (which may be substituted), alkanoylamino (which may be substituted) or N-alkyl-N-alkanoylamino (which may be substituted); Ar.sup.1 and Ar.sup.2 are each, independently, thienyl, phenyl, fluorophenyl, chlorophenyl or bromophenyl; A is Y--(CH.sub.2).sub.m --CH(R.sup.2)--(CH.sub.2).sub.n --NR.sup.1 --; R.sup.1 is hydrogen, alkyl, benzyl or --(CH.sub.2).sub.p --Y; R.sup.2 is hydrogen, alkyl (which may be substituted), benzyl, 4-hydroxybenzyl, 3-indolylmethyl or --(CH.sub.2).sub.p --Y; Y is --CN, --CH.sub.

Abstract: The invention relates to the use of a spin trap employed as an electron paramagnetic resonance measurement probe, in a cosmetic or dermatological composition for the light-protective, anti-ageing and/or anti-acne treatment of the skin. In particular, this spin trap is encapsulated in lipid vesicles which are capable of diffusing into the deep layers of the skin.

Abstract: Compounds of the following structure, the corresponding N-oxides and agriculturally acceptable salts, are disclosed as effective insecticides: ##STR1## in which U is selected from ##STR2## Q is selected from hydrogen, hydroxy, sulfhydryl, and fluorine; R is selected from a heterocycle having 5 or 6 ring atoms, optionally fused to a benzene ring, and ##STR3## wherein V, W, X, Y, Z are as defined in the specification.

Abstract: Metalloproteinase inhibitors are provided which are selective inhibitors of the action of gelatinase, and may be of use in the treatment of cancer to control the development of tumour metastases.

Abstract: A method for treating a human or non-human animal afflicted with malignant cells sensitive to parabactin or vibriobactin or a pharmaceutically acceptable salt or complex thereof comprising administering to the animal an amount of parabactin or vibriobactin effective to inhibit the proliferation of the malignant cells.

Abstract: Prostate cancer is treated with 5-[(2-aminoethyl)amino]-2-[2-(diethylamino)ethyl]-2H-[1]benzothiopyrano-[4 ,3,2-cd]indazol-8-ol or a pharmaceutically acceptable salt thereof.

Abstract: The invention is drawn to an antibiotic, NEMATOPHIN, 3-indoleethyl 3'-methyl-2-oxo-pentanamide (+stereoisomer, -stereoisomer and racemic mixture) and its derivatives, 3-indoleethyl 2-oxo-alkanamides, 3-indoleethyl 2-oxo-alkanoates with or without substitute(s) on the indole ring, produced by bacterial symbiont Xenorhabdus nematophilus and/or other Xenorhabdus species or synthesized by reaction of tryptamine or substituted tryptamine and 2-oxo-alkanoic acid or its derivative, the additional salts thereof, the pharmaceutical compositions thereof and their use as medicaments, particularly in the treatment of infectious diseases involving microorganisms susceptible to them, including antibiotic-resistant Staphylococcus.

Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.2', R.sub.2", R.sub.2'", R.sub.3 and n are as defined in the description, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable acid or base,and medicinal product containing the same useful for treating a mammal afflicted with a disorder associated to 5-HT.sub.1A or 5-HT.sub.2C receptors.

Abstract: A pharmaceutical composition containing alpha-lipoic acid, dihydrolipoic acid, metabolites of alpha-lipoic acid (inter alia bisnortetralipoic acid and tetranorlipoic acid), optical isomers R- and S- forms of alpha-lipoic acid in oxidized and reduced form together with a vitamin, especially vitamins A, B1, B2, B6, B12, C and E and their pharmaceutically acceptable salts. The compositions are useful for producing analgesic, anti-inflammatory, antidiabetic, cytoprotective, anti-ulcer, antinecrotic, neuroprotective, detoxifying, anti-ischemic, liver function regulating, anti-allergic, immune-stimulating and antioncogenic effects.

Abstract: Novel compounds of formula I ##STR1## wherein R.sup.1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moieties; and R.sup.2 is independently hydrogen, or alkyl with 1 to 6 carbon atoms.The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Ascochyta sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired formula I.Disclosed is also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in valuable crops, animals, including birds and mammals, and in the preservation of wood, paints and edible products.

Abstract: Crystalline calcium pseudomonate or a hydrate thereof, in particular the dihydrate.Processes for the preparation of these salts and their use in human and veterinary medicine and as a growth promoter in animals are described.

Abstract: N-Acylated catecholmethylamines are used to inhibit cancer cell proliferation. Specifically, capsaicin is found to inhibit growth at low concentration, but not normal cells.

Abstract: Disclosed are compounds of formula ##STR1## wherein R is hydroxy, esterified hydroxy or etherified hydroxy;R.sub.1 is halogen, trifluoromethyl or lower alkyl;R.sub.2 is halogen, trifluoromethyl or lower alkyl;R.sub.3 is halogen, trifluoromethyl, lower alkyl, aryl, aryl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl; orR.sub.3 is the radical ##STR2## wherein R.sub.8 is hydrogen, lower alkyl, aryl, cycloalkyl, aryl-lower alkyl or cycloalkyl-lower alkyl; R.sub.9 is hydroxy or acyloxy; R.sub.10 represents hydrogen or lower alkyl; or R.sub.9 and R.sub.10 together represent oxo;R.sub.4 is hydrogen, halogen, trifluoromethyl or lower alkyl;X is --NR.sub.7, S or O;W is O or S;R.sub.5 represents hydrogen, lower alkyl or aryl-lower alkyl; andR.sub.6 represents hydrogen; orR.sub.5 and R.sub.6 together represent oxo provided that X represents --NR.sub.7 ;R.sub.

Abstract: This invention relates to novel methods of increasing the level of fetal hemoglobin (HbF) in a subject and methods of treating, preventing or ameliorating .beta.-globin or other HbF-related disorders by increasing the level of HbF in a subject in need of such treatment comprising administering one or more compounds of the Formulae (I), (II), or (III):(I) XCH.sub.2 --CHX--CHX--C(.dbd.O)--O--Z(II) CH.sub.3 --CO--CH.sub.2 --C(.dbd.O)--O--Z(III) CH.sub.3 --CH.sub.2 --CO--C(.dbd.O)--O--Zwherein:X is H, or one of X only may be OH;Z is --CHR--O--C(.dbd.O)R', --CHR--O--C(.dbd.

Abstract: A method is described for alleviating the symptoms of non-rheumatoid arthritis by administering to the afflicted subject a therapeutically effective amount of cetyl myristoleate either orally, topically, or parenterally.

Abstract: This invention relates to a compound of formula I ##STR1## where the several groups are defined herein. These compounds are leukotriene antagonists and as such can be used in treating various diseases associated with leukotrienes.

Abstract: This invention pertains to a method for controlling wound scar production by administering a calcium antagonist, alone or in a combination with or followed by a steroid, to the wound site. The method can be used to minimize wound scars, such as hypertrophic wound healing disorders, keloids and burn scar contractures in humans or other mammals, particularly those individually prone to excesssive scarring.

Abstract: A method of pharmaceutically managing snoring is provided by the instillation intranasally of a solution containing 1-20% methylsulfonylmethane by weight dissolved in water so as to saturate the nasal mucous membranes. Preferably, the solution has between 10%-16% by weight methysulfonylmethane. The solution may be buffered, and/or a mild analgesic may be included. The method prefers that instillation occur as close to the sleep event as possible, and it should be at least within one hour before a person retires for sleep. The solution may be introduced by spray or drop-wise, and a product packaging the solution in a suitable container is described.

Abstract: A method for treating inflammatory bowel disease in a patient by inhibiting the production of interleukin-8 in intestinal epithelial cells by administering to said patient an enema of an effective amount of tributyrin.

Abstract: Flame-retardant foamed particles of a polyolefin resin, which contain a bis(alkyl ether)tetrabromobisphenol A flame retardant and/or a bis(alkyl ether)tetrabromobisphenol S flame retardant, and a synergist of the flame retardant, are disclosed. The flame retardant has a bromine content of at least 50 wt. %. The alkyl group in the alkyl ether moiety of the flame retardant is any one of ethyl, propyl, bromoethyl and bromopropyl. The synergist of the flame retardant is selected from the group consisting of antimony oxides, metal oxides, boric acid salts and metal hydroxides. An expansion-molded article is obtained by filling the flame-retardant foamed particles into a mold and molding the foamed particles.

Abstract: A flexible polyurethane foam is made by reacting an isocyanate with a polyol in the presence of a foam-forming agent and a fire-retardant additive. The fire-retardant additive comprises melamine and this is used in conjunction with a polyol which is of the polymer-modified polyol kind, i.e. a polyol containing a polymeric substance such as a dispersed alkanolamine/isocyanate polyaddition product.

Abstract: A gel includes a multi-component scented mixture in which the components act in concert to create a perceived scent, disposed in a polymer matrix comprising the polymerization product of one or more ethylenically unsaturated monomers. The monomers are selected such that the gel (a) has sufficient mechanical integrity to retain its shape under ambient conditions and (b) releases the components of the scented mixture in a manner that substantially preserves the native scent of the mixture upon release.