Abstract: A therapeutic medical article is provided which comprises a medical article, a precursor compound and an activator compound. The medical article is adapted, upon administration to a patient, to release the precursor compound and the activator compound such that the activator compound interacts with the precursor compound and converts the precursor compound into activated form for local delivery. Specific examples of precursor and activator compound pairs include: (a) a nitrosothiol precursor and a nitric oxide donor, (b) plasminogen and plasminogen activator, and (c) fibrinogen and thrombin.

Abstract: A method is provided for delivering a therapeutic agent to selected sites within an organism. More particularly, the invention allows for the simultaneous delivery of therapeutics to multiple treatment locations from a single catheter using a single pumping source. The catheter utilizes a microporous membrane that allows for the distribution of therapeutic agents from multiple longitudinal positions.

Abstract: The present invention provides an improved method of removing fluids, gases or other biomolecules, or delivering a pharmaceutical composition, through the skin of a patient without the use of a sharp or needle. The method includes the step of irradiating the stratum corneum, an applied pharmaceutical or an absorbing material, using a laser. By selection of parameters, the laser irradiates the selected material or tissue to create pressure gradients, plasma, cavitation bubbles, or other forms of tissue ablation or alteration. These methods increase the diffusion of pharmaceuticals into, or fluids, gases or other biomolecules out of, the body. For this invention, a pharmaceutical composition can be applied to the skin before or after laser irradiation.

Abstract: A tip of a needle is inserted into large vein of a patient. The needle is mounted in a butterfly device axially engaged to a generally cylindrical housing containing a Y-connector. Saline solution is fed to the needle through the Y-connector to the housing. A quartz optic fiber is fed through the housing and needle to the tip of the needle in the patient's venous system. A source of UV and visible light directs both UV and visible light alternatively through the optic fiber to the patient's venous system to kill pathogens in the venous system.

Abstract: A device and method for treating intraluminal tissue employ an inflatable member having a plurality of heating zones adapted for selective activation, whereby one or more of the heating zones can be activated, by one or more energy sources, to deliver heat to selected intraluminal tissue. The inflatable member can be a balloon that is attached to a catheter having a plurality of passageways for delivering fluids (i.e., liquid or air) to internal chambers of the balloon, thereby inflating the balloon. Each energy source is positioned within a corresponding chamber and may be any one of various types, including a piezoelectric cylinder, a microwave antenna, a cylindrical RF (radio-frequency) source, or a resistive heating coil.

Abstract: The present invention provides a bipolar coagulator which can be passed through the internal lumen of a ventricular catheter previously implanted into a cranial ventricle of a living subject and engaged in-situ. The bipolar coagulator will provide bipolar electrical arc currents for coagulation cauterization of adherent brain tissues, such as the choroid plexus, which occludes fluid flow into the intake drainage holes in the implanted ventricular catheter and often becomes adherent to the catheter in-situ. The cautery current provided by the bipolar coagulator is direction oriented and spatially controlled; thereby providing a better distribution of electrical current and heat within the surrounding cranial tissues; and thereby avoiding major complications of damage to intracranial structures such as blood vessels as well as avoiding the severe subarachnoid hemorrhages which are typical using other kinds of coagulation instruments.

Abstract: An apparatus for delivering energy to a biological site includes a catheter having an ablation electrode and a plurality of backplates distributed at various locations proximal the biological site. The backplates are coupled to a switching device for selecting which backplate to utilize as a return electrode to complete the circuit with the ablation electrode in order to obtain deeper, larger lesions for a given amount of energy. The backplate selection is made by determining which return electrode most closely places the biological site between the ablation electrode and the backplate. Backplate selection may be made automatically based on impedance measurements or conduction time measurements. Alternatively, the backplate selection can be made manually.

Abstract: A probe for making transmural lesions in one or more walls of the atria of the heart in open-heart surgery. The lesion blocks electrical impulses in a direction crosswise to the lesion. The probe has a handle (1), a closed electrode (2) at an end of the probe, a relatively rigid member (5) of physiologically acceptable plastic connecting the probe and the electrode, and means (6, 7) for coupling the probe to an RF power source.

Abstract: A surgical apparatus for removing a portion of tissue comprising an elongated body having a distal edge, a collapsible cutting member mounted to the elongated body, having an opening therethrough and extending distally of the distal edge of the elongated body. The cutting member has a closed loop conductive surface and is movable from a first loop configuration to a second smaller loop configuration, the exposed conductive distal edge forming an electrosurgical cutting surface for applying electrical energy to tissue. The cutting member resects a tubular region of tissue as the apparatus is advanced through tissue and the resected tissue extends through an opening in the cutting ring for containment within the elongated body.

Abstract: A screw-clamp assembly is useful for connecting a pair of spine rods in a spinal fixation system. The screw-clamp assembly includes an upper half-clamp, a lower half-clamp, an anchor screw, and a nut for clamping the half-clamps together. The upper and lower half-clamps mate to define a pair of openings for receiving the spine rods. The anchor screw is placed through an aperture in the lower half-clamp, an aperture in the upper half-clamp, and is threaded into a nut. By tightening the nut, the half-clamps are drawn together to securely grip the spine rods. A pair of screw clamp assemblies are arranged with perpendicular openings to be combined with a transverse rod to form a transverse connector assembly for bridging a pair of generally parallel spine rods.

Abstract: A spinal assembly plate. The plate can have an uninterrupted passage to accommodate a portion of a vertebral screw there through at a non-predetermined location of the plate. An apparatus can be included with sidewalls to secure the plate there between. Another apparatus can be included with a face having a frictional character to longitudinally stabilize the apparatus to the plate. A spinal assembly can be included having a vertebral screw, a spinal plate, an apparatus to secure the vertebral screw, and a connector brace to stabilize the plate. In a method of the invention, a vertebral screw can be placed through an opening of a connector brace and into a vertebral body of a patient wherein the brace includes sidewalls to stabilize a spinal plate.

Abstract: An apparatus (10, 110) for use in retaining vertebrae (V) of a spinal column in a desired spatial relationship includes a longitudinal member (12, 112) having a longitudinal axis (13, 113) extendable along the spinal column. A hook (14, 114) connects the longitudinal member (12, 112) to a vertebra (V) of the spinal column. The hook (14, 114) is connectable with the longitudinal member (12, 112) and engageable with the vertebra (V). The hook (14, 114) has a first portion (16, 116) which extends adjacent a first surface (64, 164) of the vertebra (V) when the hook is connected with the vertebra. A second portion (18, 118) of the hook (14, 114) extends adjacent a second surface (62, 162) of the vertebra (V) when the hook is connected with the vertebra so that the vertebra is received between the first and second portions (14, 114 and 18, 118).

Abstract: A spinal column fixation device includes a support member, a top seat fastened at the top end with the support member, and a bottom seat fastened at the bottom end with the support member. The top seat and the support member are fastened by an angle adjusting mechanism such that the angle between the top seat and the support member is adjustable. The bottom seat and the support member are fastened by an angle adjusting mechanism such that the angle between the bottom seat and the support member is adjustable.

Abstract: The invention concerns a connecting assembly for spinal osteosynthesis comprising a bone anchoring element including a connection zone designed to co-operate with a connecting device. The invention is characterized in that the connecting device comprises in its lower part a spherical shape designed to enable the connecting device to be freely positioned in a connector or in a linking element having a cavity with matching shape, the spherical shape forming a stop element for longitudinal positioning with the connector or with the linking element.

Abstract: Lateral connector with adjustable offset for a connection between a rod and a member for fixation to the spine, comprising a component to be connected to said fixation member and provided with an extension inserted into a second component which comprises a seat for the rod and means for immobilizing the rod and the extension when place in contact with each other. The first component comprises a head with an opening with a bearing surface of articulation cooperating with a corresponding bearing surface of the fixation member. The second component comprises an orifice for receiving the extension, permitting rotation of the second component about the extension, with the orifice intersecting the bottom of the seat to form a slot.

Abstract: Anatomically contoured anterior cervical plates with bone ingrowth surfaces, providing for intersegmental compressive preloading, and a rigid and locked interface to all of the bone screws, with those engaging the vertebrae deployed in highly convergent pairs. The bone screws have a tapered self-tapping leading end, an increasing root diameter with a generally constant outer diameter with a thread that is narrow and sharp throughout and an enlarged head portion capable of an interference fit to the receiving holes of the plate. Instrumentation consists of plate holders, a compression apparatus and a pilot hole forming device that interlocks with the plate. Methods for spinal compression and bone hole preparation are provided.

Abstract: A self-compressive and atraumatic osteosynthesis screw, includes a threaded proximal head, a body forming a threaded distal portion and, between the head and the distal part, a smooth section of short length relatively to the distal portion length, the threading thereof having a greater pitch than that of the proximal head threading, and a longitudinal channel provided from one end to the other of the screw to receive a guide pin. The screw includes a mechanism enabling it to fix small bones or small bone fragments of the skeleton after an osteotomy or a fracture, and in particular one of the five metatarsals of a human foot, including a threading diameter of the distal portion slightly greater than the diameter of the thread root of the proximal head and the diameter of the channel ranges between about 0.8 and 1.0 mm.

Abstract: A spinal cord removal tool for removing a spinal cord and spinal cord membrane from a carcass includes a spinning blade disk having multiple removal blades mounted around its perimeter, each removal blade having a forward facing cutting edge that can enter the spinal cord channel and side cutting edges that cooperate with side blades to chop the spinal cord membrane as it is brought into the tool. The side blades are adjustably mounted to move towards and away from the removal blades and compensate for changes in the width of the removal blades due to wear or sharpening. The side blade adjustment mechanism may include a self-adjusting floating mount for the side blades or a manually adjustable mount that can be set to any desired blade clearance for higher-speed and lower noise operation.

Abstract: The present invention is a rotating track cutting guide system that maintains precise alignment of a bone saw with bone tissue. The rotating track cutting guide generally includes a track subassembly and cutting guide subassemblies attachable to the bone that is to be cut. The track subassembly supports an oscillating surgical saw driver. The track subassembly is removably securable to cutting guide subassemblies which are attachable to the desired bone to facilitate a series of controlled cuts. The design of the track subassembly stabilizes the oscillating saw driver and enables it to both rotate in the plane of the saw blade and move linearly along the track.

Abstract: An instrument for distracting the disc space between adjacent vertebrae and simultaneously preparing endplates of the vertebrae includes a body having opposing upper and lower surfaces separated by curved side surfaces that extend between a posterior end of the body and an anterior end of the body. A first plurality of teeth extends across the upper surface of the body, and a second plurality of teeth extends across the lower surface of the body. The first and second plurality of teeth may constructed as ratcheting teeth that angle back toward the anterior end of the body. Also a system for distracting the disc space between adjacent vertebrae and simultaneously preparing endplates of the vertebrae, includes at least two differently dimensioned instruments as set forth above.

Abstract: Combining an implant and cement for prophylactic and/or preventative use for femoral neck augmention. A hole is drilled into the femoral neck. The hole is filled with an uncured filler cement after loose materials have been removed from the hole. Then, an open-ended tube, an implant, having openings through its walls is inserted into the hole and attached to the bone. Finally, additional filler cement is provided under pressure to the inside of the tubular implant. The filler cement flows into spaces in the bone structure via the tube wall openings. A sliding leak-tight fit between the implant and a cement injection tube permits delivery of cement at preselected locations along the implant length. Pressure is maintained until the filler cement has hardened. A strengthening factor up to was measured when osteoporotic bone was strengthened.

Abstract: In an insertion device for deforming a deformable intraocular lens to a smaller size and inserting the intraocular lens into an eye via an insertion tube, a slit is formed in an insertion end portion of the insertion tube, and cut surfaces of the slit and at least the inner wall surface of the insertion end portion are connected by curved surfaces.

Abstract: An ultrasonic calculus treatment apparatus includes a longitudinal-vibration piezoelectric oscillator for vibrating in the axial direction of an ultrasonic transmitting member and a torsional-vibration piezoelectric oscillator for vibrating about the axial direction, and further includes driving circuits for driving the piezoelectric oscillators at respective resonance frequencies and a mode selection switch for permitting the oscillators to vibrate independently or in combination, so that lithotripsy can be performed effectively in accordance with the size of a calculus or a function of an operating tool.

Abstract: An articulated apparatus is disclosed that includes a first link member, a second link member, and a third link member. The second link member is coupled to the first link member at a proximal end of the second link member by a first joint having a first axis of rotation. The third link member is coupled to a distal end of the second link member by a second joint. The movement of the third link member with respect to the second link member is governed by at least one tendon that passes through the first axis of rotation of the first joint such that movement of the second member with respect to the first member does not cause movement of the third member with respect to the second member.

Abstract: Apparatus and methods for applying fasteners during endoscopic surgery. The apparatus generally comprises a handle portion, a triggering mechanism and a fastener applicator. One embodiment of the invention forms the fastener around a single focal point on an anvil. Another embodiment vertically stacks the fasteners in a fastener applicator which is readily detachable from the handle portion by virtue of a rotational locking system and which may be replaced with a new fastener applicator having a fresh load of vertically stacked fasteners. A third embodiment of the invention has a fastener applicator having only one actuated part in its application mechanism, and makes use of biased springs controlled by position of the actuated part for the remaining part of the mechanism. A fourth embodiment of the invention deploys a plunger/ratchet assembly and pawl within the handle portion of the apparatus to ensure that the apparatus application mechanism will not reverse in the middle of a triggered application stroke.

Abstract: A tissue grasping and clipping/stapling device includes a grasping jaw assembly for grasping tissue, and a fastener delivery and forming assembly adapted for applying a fastener to tissue grasped with the jaw assembly. The jaw assembly has a spring loaded closing mechanism to secure different thicknesses of tissue and the fastener feeding and applying mechanism is adaptable to different extents of closing of the jaw assembly. The device is particularly well suited for miniature clipping/stapling such as anastomosis of coronary blood vessels and the like.

Abstract: An endoscopic suturing instrument is equipped with a needle mounted at the distal end of the suturing instrument for the purpose of living-tissue punctures. An engaging means is provided at least at the distal end of the needle for the purpose of connecting the thread while allowing it to move freely, and it is equipped with a needle-driving means to drive the needle. A loop-creating means, used to create a first loop in the thread, is provided for the suturing instrument. The first loop is formed by loosening the thread connected to the engaging means. A catching means to be inserted through the first loop to catch the thread is provided at the distal end of the suturing instrument. The thread caught by the catching means can be moved freely. The needle-driving means and the catching means are integrated into one.

Abstract: The invention provides a surgical instrument for inserting an elongate element into a human patient. In the preferred form of the invention the instrument has a curved hollow shaft defining an arc corresponding to the general curvature of a passage between the anterior vaginal wall and the abdomen of a female patient and having a cutting tip at one end and a handle at the other end. An elongate threading element is used draw a filamentary element through the shaft. Once the filamentary element is in position the shaft is removed from the patient, leaving the element in position. The instrument is preferably used to insert a U-shaped loop of filamentary material into the patient which passes around the patient's urethra and helps the patient improve her urinary control.

Abstract: A device for closing a septal defect, such as a patent foramen ovale, includes a clip formed from a superelastic material that is inserted into a septum wall of a heart. The clip is advanced through a patient's vasculature, e.g., within a delivery apparatus, until the clip is disposed within a first chamber adjacent the septal defect. Tines of the clip are directed through a flap of tissue of the septal defect until the tines of the clip are disposed within a second opposing chamber. The clip then transforms into its relaxed state, wherein the tines of the clip engage with a surface of the second chamber, thereby substantially closing the septal opening.

Abstract: A method of tracking an eye during vision correction treatment includes cutting corneal tissue to define a cut edge. At least a portion of the cut edge is tracked to track eye movements. In one embodiment, the corneal tissue is cut to define a flap-like layer such that fluid gathers near the cut edge. The fluid is illuminated prior to tracking the cut edge.

Abstract: A medical device that can be used to cut a cornea. The device may include a blade that is coupled to a head by a blade holder. The device may also have a retention spring that exerts a force on the blade and blade holder. The head and blade can be moved across a ring by a drive assembly that contains a lead screw. The ring may contain one or more openings which have a length that is greater than a width. The openings may be coupled to a vacuum source by a tube. The vacuum pressure of the tube can be displayed by a console. The console may also have switches that allow different operating parameters to be entered through a single knob.

Abstract: Apparatuses and methods are provided to reconstruct an enlarged left ventricle of a human heart, using a shaper, having a size and shape substantially equal to the size and shape of an appropriate left ventricle, wherein the shaper is adapted to be temporarily placed into the enlarged left ventricle during a surgical procedure. Another aspect of one embodiment comprises a ventricular patch adapted for placement into the left ventricle of a heart made from a sheet of biocompatible material, and having a plurality of markings coupled to the sheet, wherein the markings are configured in distinct patterns for post operatively evaluating movement of the patch. In another aspect of one embodiment, a device is presented, comprising of a handle and a sizing template adapted to be coupled to the handle. Such components are also presented as a kit for use during ventricular restoration surgery.

Abstract: A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guidewire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire.

Abstract: A basket for an embolic protection filtering device to be deployed within a body lumen for capturing embolic debris is disclosed. In one embodiment, a strut pattern forming the basket includes V-shaped struts having an internal radius at the apex with a kerf on each strut arm beginning at the radius and extending toward an opposite end of the strut. The apex may have a bulbous shape. In another embodiment, the strut arms of the basket include undulations. Also, the apices may be situated so that one apex is longitudinally staggered from an adjacent apex. The combination of features enables the basket to be crimped to a small profile while distributing stress away from the apices of the V's in the strut pattern.

Abstract: The purpose of the acupressure device for fingers designed to be inserted by the end of a finger in order to provide pressure stimulation effects with protuberances of the inner surface of the device and to enhance blood circulation effects by producing negative(−) ion. The acupressure device for fingers includes an inserting unit for the end of a finger to be inserted, at one side, a cutting unit in a center of the inserting unit, a semi-circular base unit having a flat outer surface and an inner surface cast into a plurality of protuberances, and two fixing strips at both sides of the semi-circular base unit.

Abstract: A hydraulically actuated medical instrument includes an elongated shaft having proximal and distal ends, a hydraulically actuated end effector at the distal end of the shaft and a fluid flow path extending through the shaft to the end effector. The shaft may be capable of an angled configuration where at least a portion of the shaft is manually movable to a direction in which it extends at an angle to another portion of the shaft. The end effector is not limited to a linear configuration and at least a portion of an elongated end effector extends at an angle relative to another portion of the end effector as is needed or desirable for the particular procedure to be performed.

Abstract: A delivery system for implanting medical devices within a lumen or body cavity of a patient, the delivery system having a wire formed from a plurality of layered strands yielding a reduced bending stiffness for improved maneuverability with no reduction in overall tensile strength compared to delivery systems using a single wire and of comparable diameter. The physical properties of the delivery system permit optimal placement and retrieval of an intracardiac occluder within a patient.

Abstract: An anastomosis staple comprising of a plurality of vessel engaging members and a binding structure holding the vessel engaging members together is described. The binding structure has at least one bioabsorbable element. The binding structure is rigid enough to allow for deployment and quickly resorbs to avoid problems associated with intimal hyperplasia and physical hindrance of secondary interventional procedures. The vessel engaging members may be comprised of superelastic or shape memory metal and are independent from one another. The members may be equidistant from one another and embedded within the binding structure. The composite staple can preferably serve as a drug delivery vehicle.

Abstract: The invention is based on the idea of providing an electrical therapy device which has a blocking triggering unit and a re-use blocking unit, wherein the re-use blocking unit prevents the functions of the electrical therapy device during implantation in dependence on the condition of the blocking triggering unit. The blocking triggering unit is triggered either upon implantation or explantation of the electrical therapy device.

Abstract: A subcutaneous cardiac device includes two electrodes and a stimulator that generates a pulse to the electrodes. The electrodes are implanted between the skin and the rib cage of the patient and are adapted to generate an electric field corresponding to the pulse, the electric field having a substantially uniform voltage gradient as it passes through the heart. The shapes, sizes, positions and structures of the electrodes are selected to optimize the voltage gradient of the electric field, and to minimize the energy dissipated by the electric field outside the heart. More specifically, the electrodes have contact surfaces that contact the patient tissues, said contact surfaces having a total contact area of less than 100 cm2. In one embodiment, one or both electrodes are physically separated from the stimulator. In another embodiment a unitary housing holds the both electrodes and the stimulator.

Abstract: An electrotherapy delivery device includes an upper member having a handle portion and a pediatric electrode mounted to the bottom surface of the upper member. A base member having an adult electrode is selectively attached to the upper member with a coupling mechanism to conceal the pediatric electrode. The upper member attaches to the base member across diametrically opposed corners of the base member to provide the user with a more ergonomic hand position when accessing the paddles from the defibrillator. The device further include a plurality of switches operable to deliver a charge and to select the level of charge to be delivered to the patient. The paddle is provided with a processing circuit that receives an output from separate energy level increase and decrease switches, processes the output from the switches, and outputs a signal to the defibrillator corresponding to the level of energy selected by the switches.

Abstract: A system and method for reducing the amount of noise causes by inductive elements within an implantable medical device. In particular, the invention provides a system for gradually initiating and terminating the current flow within inductive elements such as transformers that are used to charge energy storage devices such as high-voltage capacitors of an implantable cardio/defibrillator. This more gradual change in the rate of current flow prevents ground shifts and subsequent noise spikes within the device. This, in turn, allows cardiac signals to be sensed more accurately by sensing circuits, preventing oversensing, and minimizing the occurrence of inappropriate shock delivery.

Abstract: A cardiac assist system containing a device for delivering a first pacing pulse from said system to a heart, for ceasing the delivery of said first pacing pulse to said heart, for sensing whether the heart is beating, and for delivering a second pacing pulse from said system to the heart. Each of the first pacing pulse and the second pacing pulse are delivered to the heart within a period of less than about 100 milliseconds, and has a voltage of from about 2 to about 5 volts direct current. The time between the delivery of the first pacing pulse and the second pacing pulse is at least about 1 microsecond. The first pacing pulse and the second pacing pulse are delivered to the heart at a frequency of from about 2 kiloherz to about 5 megahertz; and they each have a duration of from about 0.1 microseconds to about 500 milliseconds. The cardiac assist system also contains a device for varying the voltage and/or the frequency of each of the pacing pulses.

Abstract: Various implantable medical devices (IMDs) are disclosed for implantation in a patient. The IMD includes pacing circuitry configured to selectively produce pacing pulses at a programmable pacing rate. In one embodiment, the IMD is configurable to subject a patient to a stress test. The IMD may be configurable to subject the patient to the stress test at the time specified by stored timing information, or in response to a signal (e.g., from a patient activator). Another embodiment of the implantable medical device (IMD) includes sensor circuitry, a memory for storing data, and a control unit. The sensor circuitry produces sensor data relating to cardiac condition. The control unit is configurable to store the sensor data in the memory until a trigger signal is received. Methods are described for performing a stress test in a patient with an IMD, and for subsequently reproducing cardiac operational states.

Abstract: Apparatus for treating a heart condition of a subject is provided, including an electrode device, which is adapted to be coupled to a vagus nerve of the subject. A control unit is adapted to drive the electrode device to apply to the vagus nerve a stimulating current, which is capable of inducing action potentials in a therapeutic direction in a first set and a second set of nerve fibers of the vagus nerve. The control unit is also adapted to drive the electrode device to apply to the vagus nerve an inhibiting current, which is capable of inhibiting the induced action potentials traveling in the therapeutic direction in the second set of nerve fibers, the nerve fibers in the second set having generally larger diameters than the nerve fibers in the first set.

Abstract: An implantable cardiac stimulation device is programmed to administer pacing therapy in response to a change in a patient's position and a drop in blood pressure. The stimulation device is equipped with a position sensor to sense a position parameter indicative of when a patient changes from a supine position to an upright position and a pressure sensor to sense a pressure parameter indicative of a patient's blood pressure. The device administers cardiac pacing therapy to the patient based on both the position parameter and the pressure parameter.

Abstract: An improved system and method for interconnecting an electrical device to a connector is provided. A connector assembly includes at least one connector block. The connector block may be of a type adapted to mechanically and electrically couple to an electrical lead, although any other type of connector for forming an electrical contact may be employed. The connector assembly further includes at least one weld plate. A conductor such as a wire is routed between the connector block and the weld plate and electrically coupled to both structures. The connector assembly is adapted to be fastened to a device housed within an enclosure, such as an implantable medical device residing within a can. A conductor extending from circuitry within the housing may be electrically coupled to the weld plate to thereby form an electrical connection between the circuitry and the connector block.

Abstract: An electrical connector has a compressible portion that expands to accept an inserted lead and then contracts around the lead to provide both an electrical and a spring-like mechanical connection to the lead. The connector may have a fluted pin that collapses around the lead body when a set screw of the connector port is tightened. Alternatively, a middle segment of a pin may have indentations or slots that collapse around an inserted lead body. The connector can be attached to the lead body after the lead body is implanted in the body of the patient. In lead systems in which the lead body is implanted using a guide catheter, attaching the connector to the lead body after implantation makes removal of the guide catheter much less difficult.

Abstract: The invention presents techniques for reducing the interference to telemetry from an implanted medical device caused by a source of controllable noise. In the context of an implanted system that includes a defibrillator system and a telemetry system, for example, the invention reduces the interference by suspending energy storage during telemetry. The invention further provides for suspending energy storage operation gradually rather than abruptly, by gradually reducing the duty cycle of a clock that controls the energy storage.

Abstract: Apparatus for treating a condition of a subject is provided. An electrode device is adapted to be coupled to longitudinal nervous tissue of the subject, and a control unit is adapted to drive the electrode device to apply to the nervous tissue a current which is capable of inducing action potentials that propagate in the nervous tissue in a first direction, so as to treat the condition. The control unit is further adapted to suppress action potentials from propagating in the nervous tissue in a second direction opposite to the first direction.