Abstract: The present invention provides systems and methods for selectively applying electrical energy to a target location within of a patient's body, particularly including tissue in the spine. The present invention applies high frequency (RF) electrical energy to one or more electrode terminals in the presence of electrically conductive fluid to remove, contract or otherwise modify the structure of tissue structures. In one aspect of the invention, a method is provided for treating herniated discs within a patient's spine by applying sufficient electrical energy to the disc tissue to reduce a volume of the disc, thereby relieving pressure on a spinal nerve. In one embodiment, the high frequency voltage is sufficient to ablate a portion of the nucleus pulposis, either the extruded portion outside of the annulus or a portion or all of the pulposis within the annulus.

Abstract: An elongate, malleable ablation probe including an elongate malleable body (38) and a plurality of longitudinally spaced apart electrodes (40) disposed at a distal end thereof. The electrodes (40) are separated one from another by insulative material. In one embodiment, a malleable insert is provided for insertion into a flexible longitudinal sleeve, the flexible longitudinal sleeve conforming to the shape of the malleable insert upon such insertion. In other embodiments, a malleable core is surrounded by a flexible body, the electrodes (40) being mounted to the body.

Abstract: A coil electrode for use in an electrophysiology probe includes a first material having a relatively high radiopacity and a second material having a relatively high resiliency. This combination provides the necessary levels of durability, resiliency and radiopacity. An electrophysiological probe includes a support structure, at least one first electrode defining a first radiopacity supported on the support structure and at least one second electrode defining a second radiopacity supported on the support structure, the second radiopacity being greater than the first radiopacity. When viewed under a fluoroscope, the pattern of electrodes of varying radiopacities allows the physician to distinguish between individual electrodes.

Abstract: A process for the treatment of atrial arrhythmia by use of ablation procedures comprising circumferential ablation of vessels, particularly pulmonary veins, associated with the left atrium of the heart. Also medical devices for such process including a pair of balloons secured to a catheter with one balloon located within the other balloon and an ablation catheter located within one of the balloons, which devices are used for the formation of a circumferential ablation lesion in the pulmonary vein.

Abstract: Medical devices, such as scalpels (10), needles (30) and electrosurgical knife tips (50), are provided with a silane coating (20) directly against the parent metal (16, 33, 63) of the tissue-contacting (15) distal ends (14, 37, 60) thereof whereby to impart advantageous non-stick and/or conductive properties thereto.

Abstract: A bone plate for the splinting of a fracture at a bone with a plurality of bone screws. An elastic cushion is provided between the bone screws and the bone plate in the direction towards the fracture. The screw head penetrates through the bone plate completely and lies on the bone with a contact surface under a bias force. A ring body is molded onto the elastic cushion and can be mounted at the lower side of the bone plate. The ring body and the contact surface of the screw head both project beyond the lower side of the bone plate.

Abstract: A system for securing first and second opposing facet joints together, comprising: a cannulated drill having a side opening; and an extendible member received within the cannula of the cannulated drill, the extendible member having a distal end which passes out of the side opening in a direction radially outwards from the axis of the cannulated drill as the extendible member is advanced distally through the cannula of the drill. The drill can be rotated such that the extendible member ablates opposite contacting surfaces of first and second facet joints, promoting fusion between the first and second facet joints. A facet screw passing through a hole drilled by the cannulated drill through the first facet joint and into the second facet joint is tightened into position to immobilize the first and second facet joints together.

Abstract: A surgical screw system for use with implantation rods includes a screw member, a receiver member, a pressure cap and a locking device. The screw member has a shaft and a head with a spherical undersurface and a conical tapered recess. The receiver member has an upper and lower portion, a u-shaped rod receiving channel and an axial bore. The u-shaped channel has two lateral legs at the upper portion and forms an opening leading to the axial bore. The axial bore near the lower portion includes an inwardly conical tapered surface which has a diameter larger than the shaft of the screw member but smaller than the head of the screw member. The conical surface forms a support upon which the spherical undersurface of the head of the screw member rests when the screw member is guided through the bore of the lower portion of the receiver member. The pressure cap is positioned within the axial bore and situated upon the head of the screw member.

Abstract: The invention concerns a bone screw comprising a screw shaft and a forked head into which a correction rod can be fixed. The forked head bears a nut which is connected to the forked head by a bayonet joint.

Abstract: A suture anchor and kit for anchoring a suture member to human bone. A suture anchor includes a threaded portion and has a head at the proximal end thereof, the head being generally circular. A tip is located at a distal end of the shank. The shank is at least partially threaded and includes walls defining a reel portion. The shank also includes walls for engaging a suture, the walls for engaging the suture typically adjacent walls defining the reel portion. The head typically includes walls for engaging a drive tool. The kit includes a drive tool for rotating the suture anchor when a suture member is engaged with the walls for engaging the suture such that rotation of the anchor causes the suture material to wrap around the reel portion of the shank.

Abstract: Bone fasteners consisting of a rivet and an expansion pin for attaching soft tissue and bone plates to bone. The rivet has an enlarged proximal end, a tubular body portion dimensioned to fit snugly within a hole drilled in a bone, and a distal end having expandable legs. The expansion pin is either slidably or rotatably mounted within an axial bore in the rivet. In a first embodiment, the expansion pin has a metallic traction portion and a conical, preferably bioabsorbable, distal end portion releasably affixed thereto. In use, the rivet is inserted into a pre-drilled hole in a bone. When tension is applied to the traction portion of the expansion pin, the conical end portion progressively advances into the bore thereby forcing the legs on the distal end of the rivet to expand outwardly. When the legs are fully expanded, further progress of the conical portion is arrested by a shoulder stop within the axial bore.

Abstract: A cannulated threaded bone tunnel dilator that accurately advances through bone and dilates a bone tunnel in a gentle, controlled manner, including a distal tapered, threaded tip and a body mounted on the distal end of a shaft. The proximal end of the shaft includes a drive attachment for rotating the dilator so as to threadingly advance the dilator. In use, a guidewire is driven into bone, and then the surgeon advances the dilator along the guidewire until the tip of the dilator engages the bone. The surgeon then rotates the dilator clockwise so as to threadingly advance the dilator through the bone until the dilator reaches a desired depth. After reaching the desired depth, the surgeon removes the dilator by rotating the dilator counterclockwise and retracting the dilator from the then-compacted bone tunnel. The peaks and troughs of the dilator's thread compact the bone so as to create the dilated bone tunnel.

Abstract: An implant insertion apparatus for guiding surgical instrumentation and facilitating insertion of surgical implants into an intervertebral space, including a retractor having an internal opening for introduction of a surgical instrument and positionable with respect to adjacent vertebrae in the intervertebral space, and a guide bar mounted to the retractor. The guide bar includes a longitudinal guide shaft dimensioned to guide introduction of surgical instrumentation through the internal opening of the retractor. The apparatus further includes a guide member mounted to the surgical instrument for providing the guidance thereof.

Abstract: An intraocular lens (IOL) insertion system, cartridge and/or combination cartridge and folding member that facilitates multiply folding an IOL within a load chamber of the cartridge prior to insertion in an eye. In the system embodiment, a folding member is provided in a handpiece that interacts with the cartridge to multiply fold the IOL therewithin. Alternatively, the cartridge may incorporate the folding member in its structure, or a separate folding member that interacts with the cartridge may be provided in a combination. The folding member may be a planar element that extends through a slot in the wall of the load chamber to displace a midportion of the IOL away from the inner wall of the load chamber. Desirably, the multiply folded configuration that results is an M-shape or a W-shape, depending on orientation. The cartridge may further include structure that retains the multiply folded configuration of the IOL as it passes through an injection tube and into the eye.

Abstract: A process for the mapping and/or ablation of accessory pathways around the mitral valve using a retrograde approach by use of ablation and/or mapping catheters guided by precurved guiding introducers. Also disclosed are shapes for the guiding introducers to be used for the ablation and/or mapping of the accessory pathways around the mitral valve using a retrograde approach.

Abstract: A tool is provided for use in acquiring a treatment portal on the skin surface of a patient undergoing radiation therapy or the like. The portal acquisition tool includes a template portion having a cut-out pattern for marking the treatment portal on the skin and a handle portion which both facilitates use of the template and includes ruled markings for taking measurements. Additionally, the handle portion is provided with transverse lines for assisting the therapist in altering the source-to-skin distance during the administration of electron energy and an opaque backing which serves as a screen for reflecting the optical distance indicator projected by the linear accelerator.

Abstract: The present invention is directed to a cartridge for use in a dermal abrasion system. The cartridge comprises a supply compartment and a waste compartment. The front side of the supply compartment comprises an air inlet fitting for introducing air into the supply compartment and the bottom side of the supply compartment comprises a feed tube fitting. The front side of the waste compartment comprises a vacuum inlet fitting for introducing vacuum into the waste compartment and the front side of the waste compartment comprises a return tube fitting. The present invention also includes an apparatus for use in a dermal abrasion system employing the novel cartridge and a method for removing debris in a dermal abrasion system with the novel cartridge.

Abstract: A tubular anvil sleeve is defined by at least two sleeve portions pivoted to each other for movement about an axis radially outwardly offset from an axis of the tubular anvil sleeve in its closed position. A tubular graft is inserted into the tubular anvil sleeve and a projecting end portion of the graft is folded over an exterior of the tubular annular sleeve. The tubular annular sleeve and the overfolded portion of the graft is inserted into an excised end of a blood vessel after which staples are ejected in a conventional manner. The tubular annular sleeve is removed by axial motion followed by relatively pivoting the sleeve portions about the pivot axis of the sleeve portions to open the tubular annular sleeve and effect the withdrawal/removal thereof.

Abstract: A microkeratome for keratomileusis ophthalmic surgery having a base, a carriage mounted to the base and a cutting blade carried in the carriage. The carriage is guided for movement in an axial cutting direction and the cutting blade is movable in an oscillating motion transverse to the cutting direction. In addition, the carriage is movable in the cutting direction without imparting the oscillating motion to the cutting blade.

Abstract: A blade and a blade assembly wherein the blade has a front, beveled, sharpened edge, two side edges meeting at a point spaced from the front edge and at least one attachment structure extending outwardly from each side edge. A blade holder, which extends beyond the side edges and attachment structures of the blade, sits on a top surface of the blade and is attached to the blade by a portion thereof which receives the attachment structures. The holder has an opening in an exposed surface to receive an extension from a drive mechanism such that when the drive mechanism is activated the blade is caused to vibrate or oscillate. The blade is oscillated in a lateral fashion when driven by a rod rotating along a circular path.

Abstract: A tissue cutting device includes a catheter with a window at its distal tip for admitting tissue into a catheter compartment. A cylindrical cartridge in the compartment has a cutting edge that supports an electrically conductive cutting element, e.g. a band or wire. The cutting element and adjacent tissue can be heated to a selected temperature by generating an electrical current through the cutting element. The catheter is maneuverable to position its distal end near the tissue to be cut. The catheter incorporates a vacuum feature that urges tissue into the compartment prior to cutting or severing and assists in holding the tissue during the cutting or severing process. Then, the cartridge is manipulated from the catheter's proximal end to move the cutting edge across the window, cutting the tissue. According to alternative embodiments, the cartridge is either rotated or moved axially relative to the catheter and, in either event may be capable of closing the catheter window when the cut is complete.

Abstract: A method for perforating skin including a lancet (1) held in a lancet holder (2) which, by means of a spring-loaded element (9), can be locked in a housing and moved out of the housing. To improve hygiene the invention provides for the lancet holder to be housed in a cup (5), which can be attached to the housing (8), and slidably guided in the cup.

Abstract: A retractable sharps assembly comprising a housing and a sharps unit. The housing comprises first and second open ends and a shoulder proximate the first end. The sharps unit generally comprises a frame, a shelf having a sharps member extending therefrom positioned in the frame, and at least one elastic member extending between the shelf and the forward end. As the frame is inserted into and moved forward in the hollow housing, the shelf is retained by the shoulder such that the elastic member is loaded between the shelf and forward end. A trigger mechanism interacts with the shoulder and disengages the shelf. The load in the elastic member drives the sharps member towards the forward end and through the second end opening, and simultaneously compresses the elastic member. The elastic member thereafter relaxes to retract the sharps member within the housing.

Abstract: An expansible tunneling apparatus and assosiated methods for creating an anatomic working space for a surgical procedure such as a hernia repair. Various embodiments of one and two piece apparatus that permit laparoscopic observation both during tunneling and during subsequent balloon dissection are disclosed. In a disclosed one piece embodiment, a tubular member has a bore extending therethrough and an open distal end. A lip is formed in the distal end of the tubular member to capture the distal tip of a laparoscope that is inserted into the tubular member to permit observation of the procedure both during tunneling to a desired location and during subsequent balloon inflation. An elongated neck of the balloon is secured to the tunneling member. The elongated neck permits the tubular member to be withdrawn slightly from the balloon after inflation to facilitate observation.

Abstract: An apparatus for placing a pacing electrode in the coronary sinus so as to pace the left ventricle of the heart comprises a preshaped, flexible catheter having a distal end and a predetermined shape in an unflexed or steady state condition to facilitate placement of a distal end into the os of the coronary sinus within the right atrium of the heart. The catheter includes a first lumen which extends from an entry port at the proximal end of the catheter end of the catheter, through the catheter and terminating at an exit port at the distal end of the catheter. The catheter also includes a second lumen which extends from a first port in the vicinity of the proximal end of the catheter through the catheter and terminating at a second port which is in fluid communication with an inflatable/deflatable balloon in the vicinity of the distal end of the catheter. An inflating/deflating device, such as a syringe, is attachable to the first port of the second lumen of the catheter, for inflating/deflating the balloon.

Abstract: This invention is a nasal dilator (1) for dilating a first and a second nasal passage of a nose of an animal, including a first member (2) and a second member (4) for inserting in the nostrils of the animal and maintained in a spaced-apart relationship with attachment arms (8,10) to maintain the dilator in place.

Abstract: A thrombosis filter which can be securely affixed at a selected location in the vascular system of a patient and removed when no longer required, and method for removing the thrombosis filter. An embodiment of the thrombosis filter includes a plurality of struts made from a shape memory alloy which changes shape at a temperature other than body temperature, thereby allowing removal of the filter.

Abstract: A removable vascular filter system for blocking micro- and macro-emboli while allowing the continued perfusion of blood comprises a filter membrane positioned on a guidewire, wherein a free end of the membrane sits tightly against the guidewire when the filter membrane is in a collapsed state and wherein the filter has a means for deploying the filter membrane to assume a position substantially normal to the longitudinal axis of the guidewire. The filter membrane is comprised of a fine mesh material which has a pore size capable of blocking emboli while allowing continued blood flow, a preferred embodiment of which comprises regularly spaced, laser-formed holes, and in which the membrane has a scalloped proximal profile.

Abstract: A sternal closure device comprising impermanently joined first and second clamp structures which are adapted for intercostal positioning between at least two corresponding rib pairs and substantially surround a patient's sternum each clamp having a cross member, a plurality of integrated legs and foot members, a plurality of sternum engagement surfaces, an end portion, a projection member, and a generally u-shaped receiving member wherein the end portions of each clamp member substantially extend toward one another when first and second clamp projection members are slidably received and secured in first and second clamp receiving chambers.

Abstract: A device for fixing an implant in a patient's bone which includes an expanding element which is limited in it's plastic deformation when a force is applied for fixing the implant in the bone, such that the expanding element is reversible when another force is applied for removing the implant from the bone.

Abstract: A catheter system and method are provided which change the temperature of a fluid, such as blood, by heat transfer. Selective cooling or heating of an organ may be performed by changing the temperature of the blood feeding the organ. The catheter system includes an inlet lumen and an outlet lumen structured and arranged to carry a working fluid having a temperature different from the adjacent blood. The outlet lumen is configured to induce turbulence in the adjacent fluid passing adjacent the outlet lumen.

Abstract: A radially expandable stent-graft endoprosthesis is provided. The graft included in the stent-graft is a knitted tubular structure circumferentially disposed and securably attached to the stent. The knitted tubular structure has a knit pattern of interlacing yarns in an Atlas or a modified-Atlas pattern to provide greater than 150 percent longitudinal stretchability. A knitted tubular graft and a knitted medical fabric with greater than 150 percent longitudinal stretchability are also provided.

Abstract: An expandable stent having end rings with enhanced strength and radiopacity for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in the longitudinal direction. The expandable cylindrical elements have regions which are subject to high stresses and regions subject to low stresses when the cylindrical elements are radially expanded. In order to increase the radiopacity of the stent, the width of the strut in the low stress region of the stent is designed to be wider than the width of the strut in the high stress regions. If a high radiopaque material is utilized and reduced radiopacity is desired, the width of the strut in the low stress region of the stent can be designed to be narrower than the strut width in the high stress regions.

Abstract: Disclosed is an open cell stent that has adjacent sets of circumferential struts connected by means of highly flexible, undulating, connecting struts. To decrease outward flaring of the circumferential struts when the pre-deployed stent is advanced through highly curved vessels, each unconnected strut of the sets of circumferential struts has a decreased longitudinal length as compared to the longitudinal length of the circumferential struts that are connected by the flexible connecting struts. To decrease the propensity for outward flaring of the end set of circumferential struts, the longitudinal length of the end set of circumferential struts is shorter than the longitudinal length of the interior set of circumferential struts. Also, the attachment point of the flexible connecting struts is off the center of the curved sections of the circumferential struts, thus also decreasing the tendency for outward flaring of the end set of circumferential struts.

Abstract: An implantable device or endoluminal prosthesis, such as a stent, having a sheath and a method of forming the sheath are provided. The sheath may be used for the delivery of an active ingredient. The sheath may have a selected pattern of interstices for allowing a fluid to seep through the sheath in the direction of the pattern created.

Abstract: A stent may be constructed to have at least one lockable cell which includes a first locking member and a second locking member. The first and second locking members are movable between a first position in which they are not locked together to a second position in which they are locked together and impart increased scaffolding strength to the stent.

Abstract: An intraluminal grafting system having a balloon catheter assembly, a capsule catheter assembly and capsule jacket assembly is used for deploying a graft having attachment means in the vessel of an animal body. The system contains a proximal capsule means and a distal capsule means, wherein the graft is disposed within the two capsule means and a removable sheath covers the graft and capsule means. The graft is comprised of a tubular member having superior and inferior ends, having attachment means with wall engaging members secured thereto. The balloon catheter is disposed within the capsule catheter to provide relative movement between the balloon catheter and the capsule catheter, whereby the graft can be removed from the capsule means. The balloon is inflated to firmly implant the graft and attachment means within the vessel. The graft and attachment means remain in the vessel after the intraluminal grafting system is withdrawn.

Abstract: A bifurcated stent for insertion into a bifurcated vessel such as a blood vessel. In one embodiment, a first sheet is formed into a first leg, a second sheet is formed into a second leg, a third sheet is formed into a stem, and the two legs are attached to the stem. In a second embodiment, a first sheet is formed into a member having a first leg and half of a stem, a second sheet is formed into a second member having a second leg and half of a stem, and the two stem halves are combined to form the bifurcated stent. In a third embodiment, the stent comprises two sections that are serially inserted and assembled within the vessel at the site of the bifurcation to be treated.

Abstract: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.

Abstract: Pre-trimmed, cryopreserved homografts and other stentless bioprosthetic heart valves having natural tissue sewing rings formed thereon. The sewing ring may be formed of strip of pericardium or other suitable tissue. Material may be captured between the natural tissue sewing ring and a sub-valvular lip formed on the valve to impart a desired size or shape to the sewing ring. In the case of cryopreserved embodiments of the invention (e.g., cryopreserved human homografts) the sewing ring is attached to the valve by way of a natural tissue suture, biological glue or other attachment component that is capable of undergoing cryopreservation without breaking, excessive weakening, or other changes that prevent it from performing its attachment function.

Abstract: An artificial valve for repairing a damaged heart valve having a plurality of cusps separating an upstream region from a downstream region. The artificial valve includes a flexibly resilient frame sized and shaped for insertion in a position between the upstream region and the downstream region. The frame has a plurality of peripheral anchors for anchoring the frame in the position between the upstream region and the downstream region and a central portion located between the plurality of peripheral anchors. The valve also includes a flexible valve element attached to the frame and to the central portion of the frame having an upstream side facing the upstream region when the frame is anchored in the position between the upstream region and the downstream region and a downstream side opposite the upstream side facing the downstream region when the frame is anchored in the position between the upstream region and the downstream region.

Abstract: A method for fixing a bone block in a bone tunnel comprising the steps of placing the bone block in the bone tunnel, advancing spaced-apart first and second metal wires through the bone, transversely of the bone tunnel, so as to intersect the bone block and extend through the bone block, removing one of the wires and replacing the one removed wire with a first absorbable rod, and removing the other of the wires and replacing the other removed wire with a second absorbable rod, whereby to retain the bone block in the bone tunnel with the absorbable rods.

Abstract: A process for making bone implants from calcium phosphate powders is disclosed. This process involves selectively fusing layers of calcium powders that have been coated or mixed with polymer binders. The calcium powder mixture may be formed into layers and the polymer fused with a laser. Complex three-dimensional geometrical shapes can be automatically replicated or modified using this approach.

Abstract: An intervertebral joint prosthesis having a ball component (22) for engagement with a first vertebra (26) and a trough component (24) for engagement with a second vertebra (27) adjacent to the first vertebra is disclosed. The trough component (24) includes a generally concave surface (50) having a substantially flat portion (52). When the ball component (22) and the trough component (24) are engaged to their respective vertebrae, the ball component (72) and the trough component (24) engage each other, permitting rotation and translation of the vertebrae with respect to each other. Both components include a flange (34,56) for engaging a vertebra. The invention also contemplates a method for and a tool for use in implanting a two-piece intervertebral joint prosthesis.

Abstract: The invention relates to joint prosthesis elements, to a method of manufacturing prostheses, and to a kit for putting said prostheses into place. The prosthesis element which is put into place in a resection in the joint surface is defined by a contact surface C, a fixing surface F and, interconnecting said surfaces, a peripheral surface P which co-operates with a projecting rim R of the resection. An anchoring element A projects from the fixing face and penetrates into a corresponding anchoring hole D.

Abstract: A femoral part of a knee prosthetic of the type known as comprising three compartments, including two condyles (2) and a trochlea surface part (3) wherein the femoral part is to be anchored to the distal extremity of a femur and the external surface of the condyles is to co-operate with the upper external surface of a tibia insert such that, in a longitudinal section, the trochlea support surface (3) defines a trochlean trajectory following a first circular arc and, still in a longitudinal section, the external surface of the condyles (2) includes at least partially an intermediary circular arc (5), characterised in that in a longitudinal section, the external surface of the condyles (2) comprises an intermediary surface (5) and an extremity surface (6) both of which are a circular arc, with the intermediary circular arc (5) extending over an angle of 80° to 90°, the extremity circular arc (6) extending over an angle of 40° to 50°, the value of the curvature radius of the extremity arc (6) bei

Abstract: Leaflike shaft (1) of a hip-joint prosthesis for anchoring in the femur, according to a towards a distal end (5) [sic], with a femur-anchoring section (1a, . . . 1i) having a long axis (A) and with a prosthesis neck (2), wherein the femur-anchoring section 1a, . . . 1i) has a substantially rectangular external contour in a plane perpendicular to the long axis (A), optionally with recesses in the side edges and/or at the corners.

Abstract: A method for treating morbid obesity in a body of a mammal having a gastrointestinal tract extending through a stomach and a pyloric sphincter and a wall forming the stomach and pyloric sphincter. At least one implant is formed in the wall in the vicinity of the pyloric sphincter to inhibit emptying of the stomach.

Abstract: Leather is tanned by cross-linking collagen with tris(hydroxymethyl)phosphine or a condensate of a tetrakis(hydroxymethyl)phosphonium salt with an amide or amine in a main tannage or retannage.

Abstract: An alkaline hair bleaching composition comprising (a) from about 0.01% to about 12%, by weight, of at least one oxidizing agent; (b) from about 0.2% to about 20%, by weight, of a buffering system, present in an amount sufficient to generate a pH of the composition in the range from about 5 to about 11, wherein said buffering system comprises at least one pH modifying ingredient selected from the group consisting of (i) borates buffers, (ii) alkalizing agents, and mixtures thereof; (c) from about 150 ppm to about 5,000 ppm of at least one stabilizer; and (d) from about 0.01% to about 50%, by weight, of at least one hair care ingredient selected from the group consisting of (i) surfactants, (ii) catalysts, (iii) thickeners, (iv) conditioners, and mixtures thereof.