Abstract: An orthopedic wrist splint with an initially generally planar malleable metal core covered by a layer of synthetic foam padding material on each of its opposite sides and protected by an outer cover of fabric. In one embodiment, depending on the orientation of the splint relative to the patient, the splint provides greater or lesser firmness of support when the core is bent to conform the splint to the patient's hand, wrist, and forearm. In another embodiment, a central part of the length of the splint lacks the metal core and is flexible, so that two parts of the splint are easily used on opposite sides of an arm or ankle, with the central part comfortably bent around an elbow or a foot, and with the splint firmly supporting the limb.

Abstract: An ankle fracture brace has a foot support portion which receives a foot of a patient. A convertible leg support portion receives a leg of the patient. The leg support portion includes a pair of spaced vertical arms connected by arm lower ends to sides of the foot support portion so as to extend upwardly past sides of an ankle of a patient and terminate adjacent sides of a calf of a patient. Upper end and lower end straps secure the leg support portion to the leg of the patient. These upper end and lower end straps are connected to the vertical arms adjacent the calf and ankle, respectively. A horizontal break line is formed in each of the arms between the upper end and lower end straps permitting a user to selectively sever the arms on the break lines to accommodate different patient uses of the ankle brace.

Abstract: A ureteral stent for assisting the movement of urine along a patient's ureter and into the patient's bladder. The stent includes an elongated tubular segment extending toward the bladder from a kidney end region for placement in the renal cavity to a bladder end region. A central lumen connects at least one opening at the first end region to at least one opening in the bladder end region. Thin flexible tail(s) are attached to the bladder end region of the tubular segment at a point outside the bladder so as to receive urine from the opening in the bladder end region of the tubular segment and to transport urine from there across the ureter/bladder junction and into the bladder. The tails include an elongated external urine-transport surface sized and configured to transport urine along the ureter. The urine transporting surface(s) are sized and configured to extend along at least part of the ureter, across the ureter/bladder junction, and from there into the bladder.

Abstract: A grafted network including one or more graft segments for use in coronary bypass procedures and which are configured to operably transport bypass blood flow from a singular supply location to one or more delivery locations, and which is provided in combination with one or more multiple channel blood flow connectors for directing such bypass blood flow in the grafted network to one or more vascular members requiring restorative blood flow thereto. The grafted network also preferably includes one or more devices for operably maintaining the grafted network under relatively high internal fluid pressure so as to continuously supply selective vascular members with adequate bypass blood flow.

Abstract: An apparatus including an elongate body having a lumen extending therethrough and a steering wire, having a distal portion defining a non-circular cross-section, associated with the distal portion of the elongate body.

Abstract: An intravascular catheter with micro spines that penetrate arterial wall to delivery drug or mechanical injury to the vessel wall inducing a “stent” like healing process in the vessel.

Abstract: A single use syringe assembly is provided as well as a locking element for such an assembly. The single use syringe assembly includes a barrel, a plunger rod assembly and a locking element positioned within the barrel. The locking element includes one or more barbs for engaging the inside surface of the barrel. The barbs prevent the locking element from moving proximally within the barrel, but allow its distal movement therein with the plunger rod assembly. A spring member may be provided for urging the barbs towards the inside surface of the barrel. The barbs are preferably positioned on the edge portions of opposing legs that form part of the locking element.

Abstract: A system for delivery of therapeutic and/or diagnostic agents into a living body includes a port assembly having a cannula extending from the mounting side, a port opening away from the mounting side and a resilient barrier between the port and the cannula. An access hub includes a connector positionable at the port for opening the resilient barrier. The access hub is movable in the port assembly, is engaged therewith through a resilient ring coupling and forms a seal with the resilient barrier, reducing the amount of volume to be primed. Inserters, both disposable and reusable, include the cannula insertion member as part of the assembly. A spring loaded port driver is operatively mounted within the housing with movement controlled by a latch. The driver includes a seat for receipt of a port assembly. The cannula insertion member is nonremovably fixed in a socket in the port driver in the disposable assembly.

Abstract: A system for delivery of therapeutic and/or diagnostic agents into a living body includes a port assembly having a cannula extending from the mounting side, a port opening away from the mounting side and a resilient barrier between the port and the cannula. An access hub includes a connector positionable at the port for opening the resilient barrier. The access hub is movable in the port assembly, is engaged therewith through a resilient ring coupling and forms a seal with the resilient barrier, reducing the amount of volume to be primed. Inserters, both disposable and reusable, include the cannula insertion member as part of the assembly. A spring loaded port driver is operatively mounted within the housing with movement controlled by a latch. The driver includes a seat for receipt of a port assembly. The cannula insertion member is nonremovably fixed in a socket in the port driver in the disposable assembly.

Abstract: A medical instrument for irrigation and/or suction has an instrument body in which at least one flow channel is present for the passage of a fluid, at least one shut-off member for alternately shutting off the at least one flow channel, and an actuating member for actuating the shut-off member. The at least one shut-off member is a ball which, in a closure position, lies sealingly on a sealing edge of the flow channel so that it closes off the internal cross section of the flow channel, the ball being movable, between the closure position for closing the flow channel and a release position for freeing the flow channel, substantially in a direction transverse to the longitudinal direction of the flow channel, and the actuating member for moving the ball between the closure position and the release position being movable in a direction transverse to the flow channel.

Abstract: Inventive disposable underpants are provided with an underpants member formed of a first sheet as an outermost layer and a second sheet located inside the first sheet; an absorbent member provided on the second sheet at the inner side of the underpants member; and a trunk fittable elastic member for fitting the trunk tightly held between the first and second sheets, wherein absorbent member fixing sheets each folded to form an upper and a lower portions are transversely arranged below the absorbent member, and the upper portions of the absorbent member fixing sheets are joined with a lower surface of the absorbent member, whereas the lower portions thereof are joined with an upper surface of the second sheet. Thus, even if the disposable underpants were formed using a thin absorbent member, the absorbent member could suppress a lateral leak of urine without being twisted while the disposable underpants were worn.

Abstract: A disposable diaper includes a cover member having a front waist region, a back waist region, and a crotch region and a liquid-absorbent panel disposed inside the cover member. The panel is joined to the cover member on inner surfaces of the front and back waist regions by an elastic band which extends in an elastically contractible condition in a circumferential direction of a wearer's waist. At least a portion of a clearance existing between the cover member and the elastic band is closed by a sheet material having extensibility back and forth of the diaper.

Abstract: Methods and compositions for use in perfusion applications are provided. In the subject methods, a subject or derivative thereof, e.g. isolated organ or tissue, is infused, perfused and/or transfused with at least two fluid compositions. The first fluid composition is a non-naturally occurring biological buffer free plasma-like solution and the second fluid composition is a fluid blood composition. In a preferred embodiment, an additional volume of the first solution, or a derivative thereof, is administered to the patient following introduction of the fluid blood composition. Also provided are kits and systems for performing the subject methods. The subject methods and compositions find use in variety of perfusion applications, including the treatment of hypothermic surgical applications, cryogenic procedures, and the like.

Abstract: A multilumen catheter assembly is disclosed. The assembly includes an elongated body having a proximal end and a distal end and a first lumen having a sidewall extending between the proximal end and the distal end, a first distal opening disposed at the distal end, and a first guide wire opening disposed proximally of the distal end and co-planar with the sidewall. The assembly also includes a second lumen connected to the sidewall and extending from the proximal end toward the distal end, proximally of the distal end. The second lumen includes a second opening extending obliquely away from the sidewall distally toward the first distal opening and a second guide wire opening disposed proximally of the second opening and in a plane generally parallel to the sidewall. A method of inserting the catheter into a vessel is also disclosed.

Abstract: The invention is an elongate intracorporeal member having a polymer jacket secured to a high strength shaft with the polymer jacket having an outer layer of polymeric material and an inner layer formed of polymeric adhesive. In one embodiment, a balloon catheter has a proximal high strength tubular section with a polymer jacket having an polymeric outer layer and an adhesive polymer inner layer. In another embodiment, a guidewire has an elongate core with polymer jacket disposed about at least a portion of the elongate core, wherein the polymer jacket comprises a polymeric outer layer an inner layer of polymeric adhesive disposed between and bonding the outer layer to the elongate core.

Abstract: An articulated surgical instrument for enhancing the performance of minimally invasive surgical procedures. The instrument has a high degree of dexterity, low friction, low inertia and good force reflection. A unique cable and pulley drive system operates to reduce friction and enhance force reflection. A unique wrist mechanism operates to enhance surgical dexterity compared to standard laparoscopic instruments. The system is optimized to reduce the number of actuators required and thus produce a fully functional articulated surgical instrument of minimum size.

Abstract: Methods and apparatus are provided for forming a vascular graft in vitro by axially distending a blood vessel to induce growth. The apparatus comprises a chamber containing a tissue culture medium, an inlet cannula, an outlet cannula, and a means for moving the inlet cannula, the outlet cannula, or both, to axially stretch a donor blood vessel secured between the inlet cannula and the outlet cannula in a submerged position in the tissue culture medium, wherein the inlet cannula, the outlet cannula, and the donor blood vessel are secured together to form a conduit through which the tissue culture medium can flow.

Abstract: A disposable lens for reconfiguring the cornea of an eye for ophthalmic laser surgery includes a lens which has a flat anterior surface that is formed opposite a contact surface. A skirt surrounds the contact surface and extends outwardly therefrom to define a chamber. The skirt is formed with a groove which creates a suction channel between the skirt and the contact surface in the chamber. In its operation, the lens is positioned over the cornea and a vacuum pump is selectively activated to create a partial vacuum in the suction channel. Due to this partial vacuum, the cornea is drawn into the chamber where it is urged against the contact surface of the lens. The result of this is that the cornea is flattened into a configuration where the introduction of spherical aberration and coma into a light beam passing into the cornea is reduced or eliminated.

Abstract: A method of cooling an operative surface of a cryoablation device, comprises the steps of providing a primary refrigerant under pressure and pre-cooling the primary refrigerant to a temperature below a critical temperature thereof using a non-charging refrigeration system to liquify the refrigerant in combination with the steps of expanding the pre-cooled primary refrigerant in proximity to an operative surface of the cryoablation device and removing the expanded primary refrigerant from the proximity of the operative surface.

Abstract: Electrosurgical methods, systems, and apparatus for the controlled ablation of tissue from a target site, such as a synovial joint, of a patient. An electrosurgical probe of the invention includes a shaft, and a working end having an electrode array comprising an outer circular arrangement of active electrode terminals and an inner circular arrangement of active electrode terminals. The electrode array is adapted for the controlled ablation of hard tissue, such as meniscus tissue. The working end of the probe is curved to facilitate access to both medial meniscus and lateral meniscus from a portal of 1 cm. or less.

Abstract: A low-profile surgical rod implant device is provided that allows the length of a rod spanning two bone screws to be adjusted at the time of implantation. In a separate aspect of the invention, the rod implant device can be secured by tightening and securing an end of the rod implant device at one of the bone screws. Embodiments are provided for use with polyaxial pedicle screws and substantially straight shank pedicle screws in spinal applications. In a separate aspect of the invention, a bone screw connector having an interference type fit is also provided. A method for implanting the device is also provided.

Abstract: A rongeur has a detachable crossbar to enhance cleaning and sterilization. A pin in a slot on one of the rongeur's handles is moveable out of the slot to permit extended retraction of the crossbar to a position in which it may disengage from the shank of the rongeur.

Abstract: A forceps of endoscope comprises a clip that is provided with at least three arms and a base end portion. The arms are connected to the base end portion. Each of the arms has an open-close deforming portion located close to the base end portion. A core member is provided inside the clip to be in contact with an inner surface of the open-close deforming portion at least when the arms are open. A clip open-close ring is operated by remote control performed from the base end of the sheath. The clip open-close member is engaged with the open-close deforming portion to open and close the arms with a substantially equivalent angular interval and so as to prevent each of the arms from crossing each other.

Abstract: An intracardiac suture device comprises: a first shaft assembly 1 including a first shaft 11 and a first suture needle-holding means 4 provided at a distal end of the first shaft 11; a second shaft assembly 2 comprising a second shaft 21; a third shaft assembly 3 comprising a third shaft 31 and a handling portion 33; and a puncture assembly 5 provided at a proximal end thereof with a second suture needle-holding means 51. The second shaft 21 is protrusible by sliding-movement from the distal end of the first shaft 11 toward the first suture needle-holding means 4, and a suture needle 6 is transferable between the first suture needle-holding means 4 and the second suture needle-holding means 51 when the third shaft 31 is slid to the distal end of the second shaft 21 after sliding the second shaft 21 to a position where a suture site is held between the second shaft 21 and the first suture needle-holding means 4.

Abstract: A suture shuttle in the form of a loop of flexible metallic material, such as nitinol wire, is disclosed. The flattened loop of nitinol wire is long enough to extend into an arthroscopic portal and out an accessory portal through a joint undergoing arthroscopic surgery. After installing a suture anchor in bone, a strand of suture attached to the suture anchor is retrieved through the accessory portal. Using a cannulated instrument having a sharp tip, the tissue to be repaired is pierced to create an opening. The nitinol loop is deployed through the cannulated instrument and passed through the opening. The retrieved suture strand is placed through the portion of the nitinol loop and pulled through the tissue opening before arthroscopic knots are tied.

Abstract: An inguinal hernia repair device in the form of an implantable plug that is affixed at one end to the center region of a sheet of implantable material. The plug takes the form of a plurality of hollow members, arranged so as to be in substantially parallel relationship when implanted into a defect. The hollow members are preferably tubular members and are preferably bundled together by various means, such as bonding or wrapping a band or strand about the plurality of hollow members to maintain them in adjacent and contacting relationship during insertion into a defect.

Abstract: An ear cleaner is provided to clean ears more safely. It comprises first and second body members, the first body member comprising two sections, a screen separating the two sections, one of such sections having a tube communicating with its interior and being adapted for insertion in an ear, said one section enclosing a space for receiving debris extracted from the ear and being separably connected to the other section to permit removal of such debris, the other section comprising a fan to provide a vacuum for removing debris from the ear, the second body member acting as a handle for the first body member and providing a receptacle for batteries to energize the fan. Preferably contamination is avoided by mounting the cleaner on a pedestal.

Abstract: A balloon catheter is provided having an expandable distal portion and balloon protector comprising a first removable sleeve, and an optional second removable (outer) sleeve positioned over the inner sleeve, the second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, said first and second sleeves being removed prior to use of the catheter. The first sleeve may have a variable inner diameter.

Abstract: A device for treatment of nosebleeds having an elongated body configured to be positioned between the upper gum and the portion of the face below the nose and above the top lip of a human. When so positioned intra-orally, the device exerts pressure on an area of nasal vascularization of the human. Also, a nosebleed package having a sterile inside environment and a nosebleed device packaged therein, and a box containing a plurality of nosebleed packages.

Abstract: A removable, low profile, vascular filter system for capture and retrieval of emboli while allowing continuous perfusion of blood, comprising a guidewire having proximal and distal markers, a filter delivery and deployment system, having an outer member and an inner member, and a filter removably attached near the distal end of the inner member. The filter comprises proximal and distal basket sleeves which position the filter between the proximal and distal markers on the guidewire, after the guidewire is in position past the vessel occlusion. The guidewire placement prior to filter delivery may facilitate access to the interventional site, especially through tortuous anatomy. Also, retrievability of the filter from the wire may avoid loss of guidewire position, which may occur following removal of filters permanently attached to guidewires.

Abstract: Methods and devices for delivering and/or retrieving a filter fixed to a guidewire disposed within a blood vessel are disclosed. A system in accordance with the present invention comprises, an outer shaft having a proximal end, distal end and a wall defining an outer shaft lumen. The system also includes a stop mechanism disposed within the outer shaft lumen. The stop mechanism is preferably configured such that relative axial movement between the guidewire and the outer shaft may be selectively precluded.

Abstract: A multi-barbed apparatus is provided, and methods of use, for penetrating two sides of a wound and holding the edges in apposition. The apparatus may be inserted within a wound or underneath the skin, and mechanically adheres the two sides of the wound together. The apparatus includes a biocompatible substrate carrying a multiplicity of tissue penetrating barbs on a least one side thereof, and may be formed as a rigid or flexible sheet, tube or other shape.

Abstract: The invention comprises a system and method for treating an exposed tissue of a patient with a light energy. A plurality of light emitting devices are optically coupled with a patients tissue, and apply light treatments to the tissue. A driver circuit and a controller operate to drive the light emitting devices to output different intensities of light treatment to different sub-areas of the tissue being treated.

Abstract: A device and method for providing body cooling. The cooling device applies cooling to blood flowing in a vena cavae that is then distributed throughout the body. The cooling can be assisted by use of thermoregulatory drugs or warming devices to prevent shivering and vasoconstriction.

Abstract: Method and apparatus for delivering a stent, including, but not limited to, a self expanding stent, into a body lumen. The apparatus comprises an outer tube having a proximal end and a distal end and sized to hold a stent therein in a radially constricted condition, an inner tube within the outer tube and having a proximal end and a distal end, and a holding element comprising one or more inflatable balloons carried on the inner tube at the location of the loaded stent. The balloon can be inflated prior to the procedure so that the balloon presses against the inner surface of the outer tube trapping the stent in its longitudinal position between the inner and outer tubes. Accordingly, the outer tube can be slid proximally to release the stent or distally to retract the stent back into the delivery device without the stent inadvertently sliding.

Abstract: A bio-compatible and bioresorbable stent is disclosed that is intended to restore or maintain patency following surgical procedures, traumatic injury or stricture formation. The stent is composed of a blend of at least two polymers that is either extruded as a monofilament then woven into a braid-like embodiment, or injection molded or extruded as a tube with fenestrations in the wall. Methods for manufacturing the stent are also disclosed.

Abstract: The invention concerns a flexible vascular prosthesis comprising a synthetic support impregnated with at least a covalently crosslinked dextran and/or at least a functionalised derivative of covalently crosslinked dextran. The invention also concerns a method for preparing said prosthesis.

Abstract: In an artificial heart valve for the replacement of an aortic or a mitral valve, including an annular body, which is provided at its outer circumference with means for mounting the artificial valve in place by surgical procedures and which defines in its interior a blood flow passage in which valve flap elements are pivotally supported so as to open or close the blood flow passage depending on their pivot positions, the annular body includes circumferentially spaced projections extending into the flow passage and being provided at their inner ends with pivot joints on which the valve flap elements are pivotally supported.

Abstract: A prosthesis for scleral expansion includes a central body portion and at least one end portion having a width greater than the width of the central body portion. The end portion therefore inhibits rotation of the prosthesis about a long axis when the prosthesis is implanted within a scleral pocket or tunnel. The other end of the central body portion may have a blunted end portion including grooves for receiving a edge or lip of an incision forming the scleral tunnel to inhibit the prosthesis from sliding within the scleral tunnel. Curvature of the bottom surface of the central body portion may be greater than the curvature of the innermost surface of the scleral tunnel so that contact between the scleral and the bottom surface of the prosthesis is primarily with the end portions.

Abstract: An adjustable intraocular lens system is provided by detachably attaching a secondary intraocular lens having a thin, contact lens-type optic onto a primary intraocular lens that has previously been implanted into an individual's eye. The preliminary intraocular lenses have two or more shallow, narrow slits formed adjacent the optical peripheries thereof. These slits may be formed in or through the preliminary intraocular lens optic itself or outside the optic in tabs, in haptic attachment regions or in plate-type haptics. The associated secondary intraocular lens optics are formed having two or more insertion tabs extending radially from the optical peripheries thereof. The secondary intraocular insertion tabs are shaped and located to penetrate corresponding ones of the primary intraocular lens slits and have wedge-shaped free end regions to facilitate slit insertion. The secondary intraocular lens provides a required power correction to the primary intraocular lens to which it is attached.

Abstract: The invention provides a biocompatible composite for use in a living subject for purposes of repairing damaged tissues and reconstructing a new tissue. The composite includes a biodegradable or absorbable three-dimensional support construct, a liquid or viscous fluid forming a gel matrix or viscous fluid when delivered to an area of interest in a living subject. The biodegradable construct provides an ideal surface for cell or cell extract attachment, while the gel matrix or viscous fluid acts as both a carrier material and a separator for maintaining the space between the constructs as well as the structural integrity of the developing issue.

Abstract: A vertebral replacement device for supporting adjacent vertebrae includes a vertebral body member having at least one of an upper or lower disc replacement member engaged thereto at one end thereof. The disc replacement device can be positioned in a spinal disc space when disengaged from the vertebral body member.

Abstract: Techniques and systems for distracting a spinal disc space and supporting adjacent vertebrae are provided. Trial instruments are insertable into the disc space to determine a desired disc space height and to select a corresponding implant. Implants can be also be self-distracting and the implant providing the desired disc space height can be implanted in the spinal disc space.

Abstract: A system and a method for ensuring correct insertion of the components of a femoral prosthesis, i.e. a prosthesis stem with a ball head and a cup with recess for receipt of the ball head, is described. The system comprises a tool for controlling the mutual angle between the prosthesis stem and the cup in addition to a positioning system for definition of a reference system and for determination and adjustment of the offset and length of the leg.

Abstract: A method and apparatus for performing a minimally invasive total hip arthroplasty. An approximately 3.75-5 centimeter (1.5-2 inch) anterior incision is made and the femoral neck is severed from the femoral shaft and removed through the anterior incision. The acetabulum is prepared for receiving an acetabular cup through the anterior incision, and the acetabular cup is placed into the acetabulum through the anterior incision. In one exemplary embodiment, a posterior incision of approximately 2-3 centimeters (0.8-1.2 inches) is generally aligned with the axis of the femoral shaft and provides access to the femoral shaft. In this embodiment, Preparation of the femoral shaft including the reaming and rasping thereof is performed through the posterior incision, and the femoral stem is inserted through the posterior incision for implantation in the femur. In an alternative embodiment, preparation of the femur is effected through the anterior incision, with the operative hip placed in hyperextension.

Abstract: The instant invention is an adjustable prosthetic socket. The adjustable prosthetic socket of the instant invention includes a cup, a lateral wall, and a brim. The cup includes a lateral cutaway portion, a lower closed portion, and an upper open portion. The brim is adapted for adjustable mounting in said cup via said upper open portion while the lateral wall is adapted for adjustable mounting in said lateral cutaway.

Abstract: An interconnection component or an adaptor bracket for use in coupling a distal end of a prosthetic limb socket to a proximal end of an endoskeletal component of a prosthetic limb, where the interconnection component is specifically adapted to compensate for a patient's flexion contracture.

Abstract: The invention provides a process for the production of tanned and optionally retanned leather by treatment of an optionally (pre)tanned animal hide or pelt with an aldehyde-based treatment agent (A), wherein the optionally (pre)tanned animal hide or pelt is treated with (A) an aldehyde-based treatment agent which may e.g.

Abstract: Hair dyeing composition on the basis of an oxidation dyestuff precursor reacting with peroxide, comprising at least one developing and/or coupling substance selected from the group a) 3-chloro-p-aminophenol and/or 2-chloro-p-aminophenol, b) 2-methyl-5-aminophenol, 2-methyl-5-hydroxyethyl aminophenol, 2-methyl-5-?-hydroxypropyl aminophenol, 2-methyl-5-methyl aminophenol, 2-methyl-5-ethyl aminophenol, 2-methoxy-5-aminophenol, 2-methyl-4-methoxy-5-aminophenol and/or 2-methyl-4-methoxy-5-hydroxyethyl aminophenol and c) 1-methoxy-2,4-diaminobenzene, 1-?-hydroxyethyloxy-2,4-diaminobenzene, 1-(1,2-dihydroxypropyloxy)-2,4-diaminobenzene, 1-methoxy-2-amino-4-?-hydroxyethyl aminobenzene, 1,3-bis-(2,4-diaminophenoxy)-propane, 2,4-diamino-5-methyl-phenetol and/or 1-?-hydroxyethyloxy-5-methyl-2,4-diaminobenzene.

Abstract: Water-soluble fiber-reactive dyes, preparation thereof and use thereof Dye mixtures which include the dyes of the general formula (1) and dyes of the general formula (2): their preparation and their use for dyeing or printing hydroxyl- and/or carboxamido-containing material, preferably fiber material.