Abstract: A method is disclosed for displaying endoscopic images that includes three-dimensional surfaces, variable viewing points, directions, and orientations. A computer receives a captured endoscopic image. A virtual surface is defined in the computer with the captured image textured onto the virtual surface. A virtual viewing point, virtual viewing direction, and virtual viewing orientation are defined relative to the virtual surface. A rendered image of the virtual surface is then created. The rendered image is displayed to the user. Video is displayed on the virtual surface by updating the image texture with each new frame.

Abstract: An adjusting method for endoscope systems comprises a first adjusting step, a second light adjusting step and a storing step. The first adjusting step compares video signals, which are produced from illumination light rays that are reflected from an object and whose wavelengths fall within first, second, and third ranges, with one another, and regulates a lamp current that flows into a light source lamp. The second light adjusting step adjusts a diaphragm that controls an amount of light which is emitted from the light source lamp and which is irradiated to the object. The storing step stores the lamp current regulated at the first adjusting step and a light limiting level adjusted at the second adjusting step.

Abstract: A radiolucent halo-type retractor (20) having a radiolucent curvilinear fixed member (32) connected to a radiolucent curvilinear movable member (34). Each of the fixed and movable members has a radiolucent male coupling (44, 46) projecting outward from a convex surface (40, 42) to receive a female coupling of a retractor arm. The ends (60, 68) of the movable member are separated by a distance less than a distance separating the ends (56, 64) of the fixed member. Radiolucent starburst connectors (58, 62) are disposed on first ends of the fixed and movable members to secure the fixed and movable members at a desired angular orientation. Radiolucent starburst connectors (66, 70) are also disposed on second ends of the fixed and movable members to secure the fixed and movable members at a desired angular orientation. A pin (72) rotatably connects the first ends. A locking shaft (76) rotatably connects the second ends and is operable to lock the fixed and movable members in a desired orientation.

Abstract: A blood pressure measuring apparatus oppresses blood vessels of a human body by an inflating unit through a cuff. When the blood vessels are oppressed through the cuff, a pulse wave superposed on a cuff pressure signal through a cuff pressure detector is detected by a pulse wave detector. The waveform of the detected pulse wave changes similarly to changes of pressure in the oppressed blood vessels in one heartbeat period. The information of the detected pulse wave waveform and the cuff pressure at this time are stored in a memory.

Abstract: A pulse wave measuring apparatus is disclosed, in which a sensor unit can be fixed easily under an appropriate pressure at an appropriate position on a living organism. With the living organism fixed by a living organism fixing device, a pressure sensitive portion arranged on the sensor unit is pressed against the living organism thereby to measure the pulse wave. The living organism fixing device includes a fixing stand for fixing the living organism in position, and fastening bands for connecting the fixing stand and the sensor unit and fastening the living organism fixedly to the fixing stand while at the same time activating by pressing the sensor unit against the living organism. The fastening bands include a first band portion with one end mounted on the sensor unit and the other end mounted on the fixing stand and a second band portion with one end mounted on the sensor unit and the other end removably mounted on the fixing stand.

Abstract: A system and method provides for the capture of body tissue samples such as lymph nodes. The system includes a bag formed of a flexible material having a first end opened for receiving the body tissue sample and a second end which is closed to the body tissue sample but which permits a vacuum to be pulled through the bag. The system further includes a vacuum tube in which the body tissue sample capture bag may be disposed and a vacuum source that pulls a vacuum through the body tissue sample capture bag for pulling the body tissue sample into the bag through the opened end of the bag.

Abstract: A system and method are disclosed for noninvasively diagnosing limb compartment syndrome by measuring a quantitative modulus of hardness. In the preferred embodiment, a nonmovable pressure probe mounted in the center of a movable spring loaded platform is applied against a limb compartment. Force is gradually applied to the probe and the platform, compressing a limb compartment. Pressure on the probe is measured as the probe pushes into the limb. The spring loaded platform displaces, and the distance of the probe tip to the platform is measured. This distance is the depth of compression into the limb by the probe. The relationship of incremental pressures in the probe and the corresponding distance of the probe tip to the platform for each pressure is plotted. A linear regression analysis is performed whose slope forms a quantitative modulus of hardness.

Abstract: A method for determining the anatomic condition of components of the body of a human or of an animal is disclosed comprising producing a sound signal in a selected component of the body by at least one of passive and active movements of at least one joint. The method includes recording a sound signal at a point adjacent to the selected component of the body and evaluating the sound signal. An auxiliary device selected from the group consisting of a splint, an orthosis and an exercise machine is used which ensures a repeatable movement determined by the design of the auxiliary device. The sound signal caused by the movement is recorded and evaluated by a spectral analysis of frequencies and amplitudes contained in the sound signal. A comparison is made with reference patterns of the spectral analyses for the diagnosis of the anatomic condition.

Abstract: The present invention discloses a device and method for promoting the expectoration of secretions from a patient's lungs, the method comprising the application of acoustic waves to the chest cavity of the patient through a transducer coupled to an acoustic coupling chamber, the acoustic coupling chamber being positioned adjacent an overlaying skin surface wherein the acoustic waves are of a frequency in a range of about 30 Hertz to about 120 Hertz.

Abstract: An integrated module for extracorporeal blood treatment has a flat-shaped support element which exhibits on an internal face thereof a complex of fluid distribution lines and on an external face thereof a high-flow dialyzer. The support element has a base body which exhibits fixture seatings, each of which houses an axially extended tract of a fluid distribution line. The tract of the fluid distribution line, with respect to adjacent tracts, has an increased diameter due to the presence of a junction collar made of a rigid material. Each fixture seating exhibits two axial locators for positioning the axially extended tract of a fluid distribution line in a fixed position. The locators interact with the junction collar, and the distribution lines can be fixed to the base body by a resilient fixture of the junction collars in the seatings without gluing. The module is configured to be mounted on an apparatus for intensive treatment of renal insufficiency.

Abstract: Apparatuses and methods for maintaining sterile connections during, for example, dialysis therapy. The present invention provides a container for a medical device and a lid therefore. The lid and the container are configured for an easy snap release using a cam-follower system. The invention also provides a method for using an assembly of the container, lid and a medical device within the container to maintain sterile connections.

Abstract: A flow rate selection valve includes a gate cylinder having a gate cylinder rotational axis and having at least two flow rate determining passageways and passing laterally through the gate cylinder at orientations angularly displaced from each other and having cylinder rotation structure; and a valve housing containing a flow passageway and having a cylinder receiving bore intersecting the flow passageway into which the gate cylinder is rotatably and sealingly mounted, the gate cylinder dividing the flow passageway into a passageway inlet end and a passageway outlet end, the flow passageway containing a passageway registration barrier extending across the flow passageway and sealingly abutting the gate cylinder and having several flow ports with different minimum diameters, each flow port positioned to register with one of the flow rate determining passageway.

Abstract: The present invention provides a system for delivering a therapeutic agent into tissue in combination with an implant device (2). Preferably the therapeutic substance is contained within a pellet form (14) that is deliverable into the interior of the device (2) after it has been implanted. In a preferred embodiment the implant device (2) comprises a flexible coiled spring body, the coils (4) of which have the proper diameter and spacing to contain the pellet (14) within the interior of the device (2) to contact the therapeutic agent. In treatment of ischemic tissue such as that of the myocardium of the heart, the mechanical irritation of the tissue caused by the implanted device (2) can help to provide an angiogenic effect. Additionally, the cavity (18) provided by the interior of the device (2) permits blood to pool around the pellet (14) and mix with the therapeutic agent. Several delivery systems have provided for delivering the implant and pellet (14) sequentially or simultaneously.

Abstract: A catheter includes a pull wire which extends through two different lumen and attaches to the distal end of the catheter at an off-axis location. By tensioning the pull wire, the catheter can assume various complex curves, depending on the respective lumen through which the pull wire passes.

Abstract: An infusion pump unit includes a housing sized to allow the pump unit to be carried as a portable unit. The housing contains a controllable pumping system for pumping fluid. The pump actuator is lighter, smaller, quieter and less power consuming.

Abstract: A lead screw mounting system for a syringe pump in which a second end of a lead screw is located within a connection tube that connects a drive device engaged with the lead screw to a plunger drive head. A bearing mount having diverging bearing surfaces is formed at the second end of the lead screw and a bearing having a complementary inner shape is mounted to the bearing mount. The bearing is larger than the inner diameter of the connection tube and is in constant contact with the tube. During operation, the bearing tends to move up one or the other of the diverging bearing surfaces of the bearing mount depending on which direction the connection tube is moving over the bearing creating a wedge action. The bearing functions to keep the lead screw concentrically located within the connection tube thereby increasing flow uniformity of the syringe pump.

Abstract: A medication discharge assembly useful in patient systems includes a tubular element and a stylet. In a first, closed position, the stylet is seated within the tubular element and may provide a piercing point facilitating insertion of the tubular element to a treatment site. In a second, open position, the stylet is removed from the tubular element, and the tubular element provides a travel pathway for a drug introduced to the tubular element at a proximal connection port for specific interstitial and subcutaneous diffusion and dispersion of medication along the tubular element's length near a distal discharge port through disparate perforations, which may be formed as striations of increasing length nearer the distal discharge port. The stylet in the first position may be oriented to seal this travel pathway. Depth-finding features associated with the tubular element, visually perceptible and particularly useful for placement of the assembly, may be included.

Abstract: Clip assembly part (3) for use with an adapter to the proximal end of a PEG tube. The clip assembly part (3) is configured as a loose spacer part for the external retaining part of the adapter and comprises elements (14, 15) for fixing the PEG tube to prevent it from sliding back.

Abstract: A system adapted to tend a jugular or subclavian catheter and connecting tubing includes a jugular and subclavian access site dressing and a medical tubing anchor. The dressing is adapted to protect and cover a catheter access site and the catheter. The medical tubing anchor is spacedly disposed from the dressing. The connecting tubing connects with the catheter and the system allows for movement of the tubing without the tubing exerting a pulling force on the catheter.

Abstract: A sealable access stopcock includes a valve body having a switching part formed in a valve shaft thereof for switching from one flow passage to another; and a main body having an internal chamber in which the valve shaft of the valve body is rotatably fitted, and a plurality of tributary tubes each having a lumen extending therethrough, the lumen opening on a side wall of the internal chamber; the valve body being rotated to selectively bring the lumens into communication with one another through the switching part and thereby switch flow of an infusion fluid from one flow passage to another. A switching channel is provided in the form of an arcuate groove in the switching part of the valve shaft to extend along the circumferential surface thereof.

Abstract: A medical device includes a cavity communicable with a body to deliver or to receive a fluid, and a radiation source configured to expose a portion of the cavity to radiation.

Abstract: Methods and apparatus for air content and pressure measurement of sample fluid, especially sample fluid in association with an infusion pump. Volume change in a chamber as the chamber transitions between negative and positive pressure relates to the air content in the chamber. In particular, in an infusion pump, the volume change of infusion fluid as it transitions between being under negative pressure and positive pressure within a cassette central chamber, e.g., pumping chamber, relates to the air content in the infusion fluid. The outlet pressure of the cassette central chamber, e.g., blood pressure, can be monitored based on the cassette central chamber pressure.

Abstract: An apparatus for sonoporation for transdermal delivery of a microparticles suspension containing microencapsulated drugs includes a container containing said microparticles suspension and an ultrasound horn having a tip submerged in said microparticles suspension containing microencapsulated drug or the like. The ultrasound radiation is applied to generate cavitation bubbles, thus causing pores to be formed in the skin of a patient. The ultrasound radiation intensity and distance from the skin are also effective in generating ultrasonic jets driving the microparticles through the formed pores into the skin. The ultrasound radiation is desirably applied at a frequency other than a resonant frequency of the microparticles to avoid rupturing them.

Abstract: A particle-removing medical device includes an outer, hollow tube having a tube distal end and a porous braided structure having a distal part and a proximal part. Structure, housed within the tube and having a distal end positioned distally of the tube distal end, is used to move the braided structure from a contracted condition to an expanded condition by moving the distal ends of the tube and the structure towards one another. The braided structure is constructed to inhibit particles from moving completely through the braided structure when in the expanded condition.

Abstract: Medical diagnostic ultrasound catheters are provided with improved materials for dielectric withstand strength. In one aspect, the catheter includes a braid of non-conductive material. The non-conductive braid reduces the capacitive: coupling effects and allows smaller catheters or a greater number of conductors. The non-conductive braid provides both compressive and tensile strength to transmit the torque applied to the catheter. The non-conductive braid also allows fusing of components while decreasing the risk of defective manufacture. In another aspect, a dielectric film, such as a polyester film, is positioned between the transducer and any lens or window. The dielectric film allows thinner window lenses to be used, allowing smaller catheters or larger transducers. The dielectric film may also increase the sensitivity of the transducer to acoustic energy.

Abstract: A catheter according to an aspect of the present invention comprises a flexible tubular insert section having, in the outer surface of the distal end side of the insert section, a plurality of notches arranged in the longitudinal direction of the insert section on one side of a plane passing through the longitudinal axis of the insert section, an operating wire passed through the insert section and capable of advancing or retreating to bend the distal end side of the insert section having the notches, and a reinforcing tube put on the insert section to cover substantially the overall length of the whole region of the insert section, except the distal end side of the insert section on which the notches are formed, and to restrain longitudinal compression of the insert section.

Abstract: A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms and otherwise treat heart failure (HF) and pathologies associated with HF. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infusion catheter extending to the site. A patient activator can command delivery of a dosage and/or an implantable heart monitor (IHM) coupled with a sensor can detect physiologic parameters associated with HF (or pathologies associated with HF) and trigger dosage delivery. The IIP and IHM can be combined into a single implantable medical device (IMD) or can constitute separate IMDs that communicate by any of known communication mechanisms. The sympatholytic cardiovascular agent is one of the group consisting of an alpha-adrenergic agonist and an alpha2-adrenergic agonist, e.g.

Abstract: A closed-loop control system for altering the optical characteristics of a patient's cornea includes an algorithm for predicting the shape of the cornea after one or more gas bubbles resulting from intrastromal photoablation have collapsed. Patient data can be used as an input for the algorithm, which is then run to prepare an initial treatment plan for a corneal alteration. The initial plan typically includes a plurality of intrastromal photoablation locations and corresponding ablation energies. After photoablation of plan location(s) and before the resulting bubbles collapse, a real-time wavefront shape for light passing through the cornea is measured. The wavefront is then used in the algorithm to predict a post bubble collapse cornea shape and to generate an updated treatment plan. The procedure then continues by ablating location(s) identified in the updated treatment plan. Wavefront measurement and plan updating can be repeated as many times as desired.

Abstract: A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-opposing surface for placement against a heart surface. An ablation member is coupled to the guide member to move in a longitudinal path relative to the guide member. The ablation member has an ablation element for directing ablation energy in an emitting direction away from the tissue-opposing surface. The guide member may be flexible to adjust a shape of the guide member for the longitudinal path to approximate the desired ablation path while maintaining the tissue-opposing surface against the heart surface. In one embodiment, the ablation member includes at least one radiation-emitting member disposed to travel in the longitudinal pathway. Transmurality can be assessed to approximate a location of non-transmurality in a formed lesion.

Abstract: A medical device for performing a therapeutic procedure on a patient. The medical device includes an elongate probe extending to an applicator end and a visually transparent tip positioned adjacent the applicator end. The device also includes an electrode positioned on the tip so that the electrode may be viewed through the tip. The electrode is communicative with an energy source for delivering energy to the electrode when performing the therapeutic procedure on the patient. The probe and tip are sized and shaped to be slidably received in an endoscope working channel.

Abstract: An endoscopic morcellator device and method for use is provided. The morcellator device includes an elongate shaft having a proximal end and a distal end and a lumen extending therethrough, a handle coupled to the proximal end of the shaft, at least one active electrode disposed about a periphery of the distal end of the shaft, at least one return electrode disposed at the distal end of the shaft and electrically insulated from the at least one active electrode, and at least one fluid conduit extending along the shaft and having an outlet at the distal end of the shaft.

Abstract: An endoscopic forceps for treating tissue includes a housing having a shaft affixed thereto which has first and second jaw members attached to a distal end thereof. The forceps also includes an actuator for moving jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members is adapted to connect to a source of electrosurgical energy such that the jaw members are selectively capable of operating in a bipolar mode which enables the jaw members to conduct bipolar energy through tissue held therebetween to treat tissue. The forceps also includes a monopolar element housed within the first jaw member and integrally associated with the knife. The monopolar element is selectively movable from a first position within the first jaw member to a second position distal to the first jaw member.

Abstract: The present invention has a plate and rod assembly for implantation in the cervical region of the spine which includes an occipital plate having an angled anchor bridging area that is attached to the lower posterior curve of the skull. On either side the bridging area is connected to offset legs which join flanged areas having a high friction surface and which include tethered rod anchors having rod-receiving channels. These flanges include undercut slots longer in one direction than the other to capture the side plates integral to the open U-shaped members including the rod-receiving channels. The side plates extend longer in the direction of the longitudinal axis of the rod when it is in the channel so that they can thus be lowered into the slot and rotated by 90 degrees to capture the channels in the flanges. The channels are closed by a capnut which has a bottom annular flange that also helps to lock the rod in place.

Abstract: A nail for use with repairing a bone fracture. The nail includes a cutting tip formed of at least one facet defining a cutting edge. The facet is skewed with respect to a primary longitudinal axis extending through the nail from the proximal end to the distal end. The nail further includes at least one groove extending longitudinally on the nail from the distal end to the proximal end, the groove having a cutting edge used to increase or enlarge the entry opening as the diameter of the nail increases from the distal end to the proximal end.

Abstract: A locking nail for treating fractures of tubular bones has at least one cross-bore is provided at one end for the reception of a bone screw. The nail has a female thread at the end with the cross-bore for connection to a nail retention screw. The nail has an anti-rotation feature to anti-rotationally secure the rotational position of a joining sleeve which joins a targeting apparatus relative to the locking nail.

Abstract: A canister rack system for a microdermabrasion machine has a base with bores. The base has conduits for crystal passage through the canister rack. The canisters are mountable upon the canister rack and include supply and storage canisters. The supply canister has a feeding conduit for the exit of crystal from the supply canister and the storage canister has a return conduit and a filtered conduit. The canister rack bores are formed at the base so that the conduits from the storage canister and supply canister meet with their respective conduits to form an airtight seal. A Horizontal locking pin protrudes from each canister and locks into a pair of horizontal slots formed in the canister rack. A vertical locking pin protrudes from the base of the canister rack and locks into a slot formed in each canister. A latch attaches each canister to the canister rack.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: The surgical suturing instrument incorporates a pressurized fluid suture feed system for passing a suture through the instrument and the tissues to be joined thereby. A fluid jet in communication with a suture feed conduit selectively entrains a suture in a stream of pressurized fluid, which carries the suture through the instrument's hollow tissue penetrating needle. The tissue penetrating needle may be shaped to direct the suture's free end to a point external the body cavity. Alternatively, a suture return conduit may be provided to engage the hollow tissue penetrating needle to receive and carry the suture's leading end to a point external the body cavity. External or internal pressurized fluid sources are utilized. A surface irregularity proximal the suture's leading end enhances the entrainment of the suture with the fluid stream. Individual, cartridge and spool fed sutures may all be utilized.

Abstract: Suturing instruments in accordance with the invention are dimensioned and configured to apply sutures to approximate, ligate, or fixate tissue in, for example, open, mini-incision, trans-vaginal, laparoscopic, or endoscopic surgical procedures. In some embodiments, the suturing instruments include a distal portion that is deflectably and/or pivotally coupled to the remainder of the instrument for improved maneuverability and functionality during surgery. In other embodiments, the suturing instruments are capable of housing multiple needle and suture assemblies and/or reloading the needle and suture assembly without removing the instrument from the surgical site.

Abstract: A stitching device useful for implanting suture in tissue, for example, cartilaginous tissue. The device has a frame and an elongated tubular member mounted thereto. A suture capture needle having a suture capture opening extends from a distal end of the tube. A needle cannula having a lumen is slidably mounted in a passage of the tubular member. Actuation of a trigger member pivotally mounted to the frame moves a distal end of the cannula needle and a section of suture contained in a lumen in the cannula needle through the suture capture opening causing the suture section to be retained in the opening.

Abstract: Anastomotic components may be attached to hollow bodies or vessels by magnetic or mechanical force to create an anastomosis, form a port in a vessel, or repair a diseased vessel lumen. Anastomoses are created by coupling a first connection to an end of a vessel and then attracting it to a second connector secured to the side wall of another vessel. The connection between the first and second connectors may be solidly magnetic, solely mechanical, or a combination thereof. Also disclosed are methods and devices for treating diseased vessel lumens, for example abdominal aortic aneurysm. A plurality of docking members is attached to the vessel at solicited positions, and then one or more grafts is secured to the docking members in any suitable manner.

Abstract: Apparatus and methods for treating the upper and lower beaks of poultry by non-contact heating of the upper and lower beaks of the bird are disclosed. The upper and lower beak treatment may include delivery of energy to the upper and lower beak in amounts sufficient to retard the growth and/or result in erosion of portions of both the upper beak and the lower beak. The energy incident on the lower beak may be reflected from a lower beak energy director (e.g., a reflector) or it may be provided a separate energy source.

Abstract: A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

Abstract: A method and system of performing an intravascular procedure at a treatment site in a vessel of a patient. A device creates a seal to prevent the flow of blood during the treatment of vascular disease. A seal may be formed between the distal inside diameter of a sheath or catheter such as a guide catheter as well as within a vessel, such as an artery or vein. An elongated device having a distal portion extending from the catheter and having a fluid impermeable membrane disposed about at least the distal end of the device is used to seal the vessel. The system includes a device to occlude blood flow and a distal protection device to filter or remove embolic debris.

Abstract: A device and method for protecting a blood vessel, and hence bodily tissues, against damage caused by particulate such as an embolus. The device may be a stent, for insertion in a large artery such as the ascending aorta, and may be combined with a filter. In one embodiment, the device includes an outer wire frame rather than a stent. The stent may be made of at least one layer of mesh, which is typically attached or mounted to the arterial wall. Typically only part of the stent is attached (for example at a reinforcing ring structure). Typically the size of the apertures of the mesh at the top portion of the stent is smaller than the bottom portion of the stent. The device and method are particularly useful in preventing blockages of flow to the brain, but have other uses as well. An electric charge may be placed on the device, for example, to prevent blood components from collecting.

Abstract: The present invention is directed to a multi-functional surgical wound closure/transfer marking device comprising a substrate having a proximal surface, a distal surface and markings; an adhesive layer having a proximal surface, a distal surface and being disposed on the proximal surface of substrate; and a primary release sheet having a proximal surface and a distal surface, being in two portions that are disposed releasably adherently to the proximal surface of the adhesive layer. The device has transferable markings on the proximal surface of the second portion of the primary release sheet, where the transferable markings are substantially aligned with the markings on the substrate.

Abstract: A suture anchor is described which in one form may be easily fabricated from extruded material by angular cuts and bore holes which provide an offset pulling force to the suture. In an alternate and preferred embodiment the suture anchor is injection molded having an annular displaced corner and abutment wall which act to seat the suture anchor firmly within a bore hole. Novel application means are also disclosed which hold the suture anchor on a frangible shaft for insertion and upon completion of the insertion permit fracture of the frangible portion and removal of the instrument.

Abstract: A method of treatment of a scar comprising applying a topical silicone gel to the scar, and wiping off the excess to leave a thin layer of the gel on the scar. Applications of the topical silicone gel can be alternated with applications of silicone gel sheeting to the scar. The method may further include treating the scar with laser therapy.

Abstract: A fluid warming cassette for use in a fluid warming system includes a first sheet and second sheet joined with a flexed tensioning rod to form a fluid container with a periphery in which the flexed tensioning rod is disposed to tension the fluid container. The fluid container includes a fluid channel with inlet and outlet ports in fluid communication with the fluid channel. Preferably, the rod is flexed into an open-ended shape such as a “U” shape. So flexed, the rod tensions the fluid container, adding structural stability to the fluid warming cassette.

Abstract: Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and/or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ.