Abstract: A structure includes a layer which includes a first cured portion and a second cured portion which are formed from a same light curable material. The first cured portion is cured to a first amount, and the second cured portion is cured to a second amount. The first amount is sufficiently different than the second amount to result in a visible discontinuity on the surface of the structure. A method for forming a pattern in a radiation curable material includes providing between a radiation source and the radiation curable material, a pattern that can block a portion of the radiation from the radiation source. The material is cured with radiation from the radiation source to form a pattern in the radiation curable material.

Abstract: A composite construction 1 is obtained by coating the outer periphery of a core material 2 with a shell layer 3. The core material 2 is composed of a first sintered body that is obtained by bonding, with a binder metal, a first hard particle composed of one or more of carbides, nitrides and carbonitrides of metals of Groups 4a, 5a and 6a of the Periodic Table, or a first ceramics obtained by bonding, with a sintering additive, a first ceramic particle composed of at least one of oxides, carbides, nitrides and carbonitrides selected from the group consisting of metals of Groups 4a, 5a and 6a of the Periodic Table, Al, Si and Zn. The shell layer 3 is composed of a second hard sintered body or second ceramics having a different composition from the first hard sintered body. The ratio of the residual free carbon amount Cin in the core material 2 to the residual free carbon amount Cout in the shell layer 3, Cin/Cout, is 0.5 to 2.

Abstract: The invention is a process for the preparation of article comprising placing a film on each inner surface of each part of a two part mold; placing an article in the mold with film located between the surface of the mold and the article such that there is a small space between the article and the surface of the mold; closing the mold about the article; injecting between the film and the article an expandable plastic material under conditions that the article is coated with the expandable material and the expandable material does not expand; removing the plastic article with the expandable material coated thereon with the two films attached to the expandable plastic material. In another embodiment the invention is an article comprising a shaped plastic article; an expandable material coated in the shaped plastic article; and a film covering the material coated shaped plastic article.

Abstract: A method of making a foamed rubber member includes the steps of: a) Stirring and pressing the foaming raw material repeatedly, wherein the foaming raw material has rubber, an accelerator, and foaming agent mixed in a predetermined ratio. b) Molding the foaming raw material into a meshed rubber sheet. c) Softening a surface of the meshed rubber sheet. d) Resting an attachment on the surface of the meshed rubber sheet and pressing the attachment. e) Vulcanizing and foaming the meshed rubber sheet to have a foaming member.

Abstract: Acid-neutralizing filter media includes filter media fibers in combination with a strong base of small particle size and high surface area attached to and immobilized on the filter media fibers, and methodology therefor.

Abstract: The invention relates to a pelletized organopolysiloxane material, to a process for producing the pelletized material, and to the use of the pelletized organopolysiloxane material as an additive for thermoplastics.

Abstract: A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

Abstract: There is provided a composition comprising a unique polymeric compound that provides a soft, flexible product. There is also provided a unique polymeric tampon applicator that is soft and flexible. When used as a tampon applicator barrel, the barrel is more comfortable and has improved ease of insertion. The polymeric compound primarily comprises a thermoplastic resin and a block copolymer that exhibit unique load, energy and modulus of elasticity properties. The polymeric compound should also include a plasticizer and a compatibilizer/flow modifier, and may include a slip/mold release agent, an antioxidant, and even a pigment. There is also provided a method for making the polymeric compound that will be formed into a product, such as an applicator or applicator barrel in which all of the above ingredients, except for the thermoplastic resin, are combined and formed into soft pellets. The soft resin pellets are then dry blended with pellets of the thermoplastic resin.

Abstract: The invention relates to a manufacturing inspection method for the cyclic production of injection-molded parts in multi-cavity casting molds involving a row-by-row monitoring of the injection-molded parts after they are removed from the casting molds, said monitoring being effected by sensors, particularly, photoelectric barriers. The invention also relates to an inspection device used during the cyclic production of injection-molded parts in multi-cavity casting molds involving a row-by-row monitoring of the injection-molded parts after they are removed from the casting molds, said monitoring being effected by sensors, particularly, photoelectric barriers.

Abstract: A method for hot hydrostatic pressing by means of working liquid which tends to become unstable within a transition time when in contact with a blank heated to a high working temperature and at a pressure lower than the liquid's stabilization pressure. The pressing of the blank heated to the high working temperature is carried out by raising the pressure of the working fluid to said stabilization pressure for a time shorter than the transition time. This is achieved by surrounding the heated blank by a cover adapted to delay the contact between the heated blank and the working liquid until the pressure in the working chamber is raised.

Abstract: An apparatus for enabling fabrication of accurate angular cuts in a pipe includes a first fixture adapted to be clamped on a pipe and adjusted relative to the pipe so as to define a substantially planar surface aligned with a desired cut angle relative to a longitudinal axis of the pipe and a second fixture adapted to mount a cutting torch and enable sliding the mounted cutting torch on the planar surface defined by the first fixture and relative to the pipe such that the torch can fabricate a cut in the pipe at the desired cut angle.

Abstract: A device for use when hardening includes fixture parts (1, 4, 6) between which a workpiece is fixed during hardening. The device's fixture parts (1, 4, 6) are three or more so that two or more workpieces are fixed simultaneously in the device.

Abstract: A steel powder metal skeleton is infiltrated with an infiltrant composition similar to the skeleton, with an additional agent that depresses the melting point of the infiltrant relative to the skeleton. Infiltration is driven primarily by capillary pressure. The powder and infiltrant compositions differ primarily only in a higher concentration of a melting point depressant agent “MPD” in the infiltrant. Carbon (C) and silicon (Si) and several other elements can be elements in an MPD, either alone or in combination. Certain steel target compositions are such that a complementary infiltrant, and skeleton can be chosen such that a skeleton will remain solid at an infiltration temperature at which the infiltrant can be melted and fully infiltrated, and further where there is a persistent two phase field, with a liquid phase that is large enough (greater than 7% vol, and typically between 20 and 40 vol %) so that flow can be maintained without choke off from diffusional solidification.

Abstract: Provided is a Pb-free solder alloy used for mounting electronic parts on a printed circuit board. The Pb-free solder alloy is highly resistant to oxidation and impact. The Pb-free solder alloy includes Ag of 2.8 wt % to 4.2 wt %, Cu of 0.3 wt % to 0.8 wt %, Ge of 0.0001 wt % to 0.01 wt %, In of 0.001 wt % to 0.2 wt %, and the balance of Sn. The Pb-free solder alloy having this composition also has a high shear strength and low brittleness factor after bonding. Thus, the Pb-free solder alloy has high quality mechanical properties, to form a high quality joint.

Abstract: The invention is a method for controlling growth of spores of specific fungi to the vegetative state by introducing a salt of formic acid to an aqueous system forming a mixture, applying the mixture to a surface where fungal spore growth control is desired, and drying the surface with the mixture disposed thereon, thereby forming an ionic lattice on the surface that prevents fungal spore growth to a vegetative state.

Abstract: An apparatus for conditioning mammalian blood for subsequent use in a medical procedure includes a cabinet having a secure environment and a door providing the only access to the environment. An input system transports a blood charge from a source to the cabinet and a flask is removably contained in the secure environment and coupled to the charge input system to receive the charge. Stressors are coupled to the cabinet and positioned for operation to create a conditioned charge in the flask. An output system is coupled to the flask and includes a receiver for the conditioned charge. The apparatus includes an automated control system operable upon closing the door to lock the door and to then condition the charge, and to then cause the charge to move from the flask to the receiver.

Abstract: A system and method for detecting the presence of submicron sized particles in a sample taken from the environment includes a collecting a sample from the environment and purifying and concentrating the submicron particles in a sample based on the size of the particles. The purified and concentrated particles are detected with an apparatus which includes an electrospray assembly having an electrospray capillary, a differential mobility analyzer which receives the output from the capillary, and a condensation particle device for counting the number of particles that pass through the differential mobility analyzer.

Abstract: A dispensing device has a cantilever comprising a plurality of thin films arranged relative to one another to define a microchannel in the cantilever and to define at least portions of a dispensing microtip proximate an end of the cantilever and communicated to the microchannel to receive material therefrom. The microchannel is communicated to a reservoir that supplies material to the microchannel. One or more reservoir-fed cantilevers may be formed on a semiconductor chip substrate. A sealing layer preferably is disposed on one of the first and second thin films and overlies outermost edges of the first and second thin films to seal the outermost edges against material leakage. Each cantilever includes an actuator, such as for example a piezoelectric actuator, to impart bending motion thereto. The microtip includes a pointed pyramidal or conical shaped microtip body and an annular shell spaced about the pointed microtip body to define a material-dispensing annulus thereabout.

Abstract: A fluid catalytic reactor vessel having at its upper end a single centrally positioned primary cyclone having a gas-solids inlet fluidly connected to the downstream end of a fluid catalytic riser, which riser is positioned externally from a fluid catalytic reactor vessel. The primary cyclone is further provided with a gas outlet conduit at its upper end fluidly connected to one or more secondary cyclone separators, which secondary cyclone separators are positioned in the space between the centrally positioned primary cyclone and the wall of the reactor vessel and which secondary cyclones have means to discharge solids to the lower end of the reactor vessel and means to discharge a gaseous stream poor in solids to a gas outlet of the reactor vessel. The primary cyclone is further provided with a primary stripping zone at its lower end and means to discharge pre-stripped solids from the primary cyclone to the lower end of the reactor vessel.

Abstract: Systems, apparatus, and methods for the catalytic removal of at least one pollutant from an air stream via a catalytic precooler arranged in series with at least one augmentative catalytic device. The augmentative catalytic device may be located upstream or downstream from the catalytic precooler. The augmentative catalytic device may be integrated with the catalytic precooler, thereby eliminating the need for a separate housing and minimizing weight. Alternatively, the augmentative catalytic device may be disposed within a separate housing, thereby facilitating access for maintenance and decreasing direct maintenance costs.

Abstract: Device for mixing and distributing a dense, generally liquid, fluid and a light, generally gaseous, fluid, placed in a reaction chamber upstream from a granular bed (70) or between two successive granular beds, the said device being characterized by a tubular system (50) for the introduction of dense fluid from outside the reactor, up to a level lower than the level of establishment of the interface between the dense fluid and the light fluid, situated above the plate and preferably more or less next to that of the plate (62). Application of this device to any type of gas/liquid reaction in a fixed bed in particular for hydrotreatment.

Abstract: The invention concerns a device for spraying water in a feedwater tank of a thermal power plant. Because the spraying device comprises a catalyst for the conversion of the gases contained in the water, the gases released from the water during the spray degasification can be removed easily, reliably and completely. Thus, the degree of efficiency of the thermal circuit of the power plant and the lifespan of the components arranged in the circuit are increased.

Abstract: Novel methods for the removal of sodium perchlorate from electrolytic processes for the production of sodium chlorate have been discovered, allowing sodium chlorate production processes to proceed with low levels of sodium perchlorate. A portion of the mother liquor from the sodium chlorate crystallization is fed to a secondary crystallization step to concentrate sodium perchlorate in a second mother liquor. In this manner, at least a portion of the sodium perchlorate in the sodium chlorate production process is isolated in the second mother liquor, which can be removed from the sodium chlorate production process. The process is run until the concentration of sodium perchlorate in the second mother liquor reaches a desired concentration, at which point at least a portion of the second mother liquor can be removed, thereby removing a portion of the sodium perchlorate from the sodium chlorate production process.

Abstract: An apparatus for sterilizing various articles includes a chamber defining an airtight space and an entrance and exit. A vacuum pump is coupled to the chamber for withdrawing air therefrom which reduces the chamber air pressure. An ozone generator is coupled to the chamber for introducing ozone at atmospheric pressure therein following air withdrawal. This causes efficient diffusing of the ozone into the article for sterilizing it against anthrax. The ozone is then withdrawn into an ozone filter having a non-consumable catalyst for converting the ozone back into oxygen. The apparatus may be implemented using single or multiple chambers. In multiple chamber embodiments, a conveyor extending through water chambers may be utilized for conveying textile articles while more traditional conveyors may be utilized for mail articles.

Abstract: A method is provided for the preparation of a hydrogen storage medium having a high hydrogen storage capacity, high reversibility and fast reaction time. A high storage capacity Li3N-containing media with high reversibility is also provided.

Abstract: The invention incorporates new processes for the chemical modification of carbon nanotubes. Such processes involve the derivatization of multi- and single-wall carbon nanotubes, including small diameter (ca. 0.7 nm) single-wall carbon nanotubes, with diazonium species. The method allows the chemical attachment of a variety of organic compounds to the side and ends of carbon nanotubes. These chemically modified nanotubes have applications in polymer composite materials, molecular electronic applications and sensor devices. The methods of derivatization include electrochemical induced reactions thermally induced reactions (via in-situ generation of diazonium compounds or pre-formed diazonium compounds), and photochemically induced reactions. The derivatization causes significant changes in the spectroscopic properties of the nanotubes. The estimated degree of functionality is ca. 1 out of every 20 to 30 carbons in a nanotube bearing a functionality moiety.

Abstract: A method for growing single-wall carbon nanotubes involves preparing a catalyst comprising catalytic metals, iron and molybdenum, and magnesium oxide support material and contacting the catalyst with a gaseous carbon-containing feedstock at a sufficient temperature and for a sufficient contact time to make single-wall carbon nanotubes. The weight ratio of iron and molybdenum can range from about 2 to 1 to about 10 to 1 and the metals loading up to about 10 wt % of the MgO. The catalyst can be sulfided. Methane is a suitable carbon-containing feedstock. The process can be conducted in batch, continuous or semi-continuous modes, in reactors, such as a transport reactor, fluidized bed reactor, moving bed reactors and combinations thereof. The process also includes making single-wall carbon nanotubes with catalysts comprising at least one Group VIB or Group VIIIB metal on supports such as magnesia, zirconia, silica, and alumina, where the catalyst is sulfided.

Abstract: The present invention comprises a method of treating an off-gas stream from a refining process to remove sulfur compounds. A portion of the off-gas stream containing hydrogen sulfide is injected at the front end of the thermal reactor and in at least one other location downstream of the thermal reactor. A ratio of hydrogen sulfide to sulfur dioxide at the outlet of the thermal reactor is less than the stoichiometric requirement. The ratio is adjusted downstream of the thermal reactor so that a ratio of hydrogen sulfide to sulfur dioxide is maintained substantially in excess of the stoichiometric requirement for a Claus reaction. The tail gas, containing hydrogen sulfide but virtually no sulfur dioxide, is treated by a process including removal of water and introducing sulfur dioxide into the tail gas in a stoichiometricly balanced quantity and processing the tail gas in a Claus reactor.

Abstract: A chemical reaction is performed with separation of the product(s) and reactant(s) by pressure swing adsorption (PSA), using an apparatus having a plurality of adsorbers cooperating with first and second valve assemblies in a PSA module. The PSA cycle is characterized by multiple intermediate pressure levels between higher and lower pressure of the PSA cycle. Gas flows enter or exit the PSA module at the intermediate pressure levels as well as the higher and lower pressure levels, entering from compressor stage(s) or exiting into exhauster or expander stages, under substantially steady conditions of flow and pressure. The PSA module comprises a rotor containing the adsorbers and rotating within a stator, with ported valve faces between the rotor and stator to control the timing of the flows entering or exiting the adsorbers in the rotor. The reaction may be performed within a portion of the rotor containing a catalyst.

Abstract: Integrated Combustion Reactors (ICRS) and methods of making ICRs are described in which combustion chambers (or channels) are in direct thermal contact to reaction chambers for an endothermic reaction. Particular reactor designs are also described. Processes of conducting reactions in integrated combustion reactors are described and results presented. Some of these processes are characterized by unexpected and superior results, and/or results that can not be achieved with any prior art devices.

Abstract: A process for the co-precipitation of a substance with a stabilizer therefor, by a gas anti solvent process comprising introducing into a particle formation vessel a supercritical fluid pure or mixed with a modifier; and a solution comprising said substance and said stabilizer dissolved in a solvent; so as said solvent is extracted from the solution by said supercritical fluid and co-precipitation of the substance and stabilizer occurs. The process may be carried out using an apparatus, for example, shown in FIG. 1, comprising a particle formation vessel (22) and a nozzle (27) having a central orifice (39) serving to introduce a solution of the substance and a plurality of outer orifices (41) serving to carry a flow of supercritical fluid into the particle formation vessel (22), such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron sized particles of the substance/stabilizer occurs.

Abstract: This invention comprises new formulations of radiographic contrast media including dimeric non-ionic media, with an organic amine and a carboxylic acid. Formulations of this invention increase the biological tolerance of such media, thereby increasing their safety.

Abstract: A radio-opaque dihydroxy compound substituted with at least one bromine or iodine atom. Radio-opaque medical implants and drug delivery devices and methods for therapeutic site-specific or systemic drug delivery comprising implanting in the body of a patient are also disclosed.

Abstract: To eliminate a defect in conventional dental bleaching agent, that light for activating titanium oxide hardly reaches down to the titanium oxide at the teeth surface to be bleached, a dental bleaching agent set consists of two components of which the first component is attached to teeth surface and irradiation of light is followed after the second component is contacted on the teeth surface, the first component consisting of an organic solvent, containing at least one of a titanium oxide, a nitrogen doped titanium oxide, and a titanium oxinitride having photocatalytic activities, and preferably one or more of a metal oxide, a metal salt, and a metal powder, a thickener and water, the second component consisting of a compound that produces hydrogen peroxide in water, a thickener and a carrier.

Abstract: Topically applicable, solid UV-photoprotecting compositions suited for the UV-photoprotection and/or makeup and/or care of the lips and/or the face, advantageously shaped as sticks, contain a) at least one fatty phase, a UV-photoprotecting amount of b) at least one organic UV-screening agent and c) a fraction of metal oxide mineral nanopigments, and d) an SPF-increasing amount of at least one octenylsuccinic anhydride-esterified starch salt, formulated into a physiologically acceptable medium therefor.

Abstract: Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

Abstract: Cosmetic compositions and methods, particularly for skin lightening, using compound and derivatives of general formula I and/or II as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle: Where each R, independently, represents a hydrogen atom, C1–C4 acyl group, or C1–C4 alkyl group. Preferably, the compound is 4-hydroxyphenylpyruvate, i.e., where each R in the formula I is Hydrogen.

Abstract: Compositions comprising at least one ester which comprises at least one aromatic group, which is liquid at room temperature and which is derived from esterification with (i) at least one aromatic acid of (ii) at least one hydroxyl group of at least one hydroxylated aliphatic compound chosen from hydroxylated aliphatic acids and esters of hydroxylated aliphatic acids, wherein said at least one hydroxyl group is chosen from pendant hydroxyl groups and terminal hydroxyl groups. The inventive compositions may be used for, for example, making up the face, body or superficial body growths of human beings and may constitute, for example, a lipstick, a lip gloss, a tattooing product, an eye shadow, a mascara, a product for caring for the hair or a nail varnish.

Abstract: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (?D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (?D20) of +58° are also novel.

Abstract: Disclosed and/or claimed is subject matter including: equine GM-CSF, its amino acid sequence, nucleic acid molecules encoding equine GM-CSF, use of equine GM-CSF as an adjuvant or non-specific immunity stimulant, compositions containing equine GM-CSF and vectors expressing GM-CSF.

Abstract: The present invention relates to novel bacteria inhibiting halitosis or oral malodor. In particular, the present invention relates to novel lactic acid bacteria belonging to the genus Weissella, which can inhibit the proliferation of anaerobic bacteria producing volatile sulfur compounds by interacting with them and generating hydrogen peroxide under aerobic and anaerobic conditions. These lactic acid bacteria of the present invention are isolated from lactic acid bacteria naturally existing in the oral cavity of a person, and identified and deposited as Weissella cibaria CMU (Accession No.: KCTC 10650BP), Weissella cibaria CMS-1 (Accession No.: KCTC 10678BP), Weissella cibaria CMS-2 (Accession No.: KCTC 10679BP) and Weissella cibaria CMS-3 (Accession No.: KCTC 10680BP), respectively.

Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

Abstract: The present invention relates to an anti-idiotype antibodies directed against the monoclonal antibody (HmenB3) to Neisseria meningitidis serogroup B and hybridomas producing the anti-idiotype antibodies. This invention is also directed to vaccine compositions comprising the anti-idiotypic antibodies in combination with pharmaceutically acceptable carriers. These vaccine compositions can be used to prevent or treat the serogroup B meningococcal disease.

Abstract: The present invention relates to at least one novel anti-TNF antibodies, including isolated nucleic acids that encode at least one anti-TNF antibody, TNF, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

Abstract: The present invention relates to materials and methods for treatment of hepatitis C. More closely, the invention relates to human monoclonal antibodies against HCV E1 antigen, to a reagent comprising such antibodies, and to vaccine compositions comprising such antibodies. Futhermore, the invention relates to a method of treating or preventing HCV infection by administration of a vaccine composition comprising the monoclonal antibodies of the invention.

Abstract: A monoclonal antibody which binds to baboon and human CD2, and in particular LO-CD2b antibody. The antibody may be employed to prevent and inhibit an immune response in human patients, such as when the immune response is mediated by the activation and proliferation of T-cells or natural killer cells.

Abstract: This invention relates to novel fusion proteins which are comprised of a targeting protein that binds tissue factor (TF), which is operably linked to the thrombomodulin (TM) EGF456 domain alone or in combination with at least one other TM domain selected from the group consisting of the N-terminal hydrophobic region domain, the EGF123 domain, the interdomain loop between EGF3 and EGF4, and the O-glycosylated Ser/Thr-rich domain, or analogs, fragments, derivatives or variants thereof. The fusion protein binds at the site of injury and prevents the initiation of thrombosis. The fusion protein can be used to treat a variety of thrombotic conditions including but not limited to deep vein thrombosis, disseminated intravascular coagulation, and acute coronary syndrome.

Abstract: Compositions of pro-IFG-I E-peptides for the treatment and amelioration of tumor-producing diseases, and methods for their utilization.

Abstract: Synthetic DNA molecules encoding the HPV45 L1 protein are provided. Specifically, the present invention provides polynucleotides encoding HPV45 L1 protein, wherein said polynucleotides have been codon-optimized for high level expression in a yeast cell. The synthetic molecules may be used to produce HPV45 virus-like particles (VLPs), and to produce vaccines and pharmaceutical compositions comprising the HPV45 VLPs. The vaccines of the present invention provide effective immunoprophylaxis against papillomavirus infection through neutralizing antibody and cell-mediated immunity.

Abstract: Chimeric parainfluenza viruses (PIVs) are provided that incorporate a PIV vector genome or antigenome modified to encode a chimeric glycoprotein incorporating one or more heterologous antigenic domains, fragments, or epitopes of a second, antigenically distinct HPIV. These chimeric viruses are infectious and attenuated in humans and other mammals and are useful in vaccine formulations for eliciting an immune responses against one or more PIVs, and, optionally against respiratory syncytial virus (RSV). Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric PIV genome or antigenome which includes a HPIV vector genome or antigenome combined or integrated with one or more heterologous genome segment(s) encoding one or more antigenic determinant(s) of a heterologous PIV to encode a chimeric glycoprotein.