Patents Issued in August 14, 2007
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Patent number: 7255822Abstract: A method of manufacturing a composite sheet includes perforating a reinforcement panel. A mold surface onto which the composite sheet may be formed is provided. At least one outer coat of material is applied onto the mold surface. At least one coat of resin and reinforcement material is applied over the outer coat to form a reinforcement layer. The perforated reinforcement panel is applied to the reinforcement layer, and the resin is forced into the perforations formed in the reinforcement panel, thereby bonding the reinforcement layer to the reinforcement panel.Type: GrantFiled: January 31, 2002Date of Patent: August 14, 2007Assignee: Owens-Corning Fiberglas Technology Inc.Inventors: James G. Bledsoe, Donald C. Ray, Mark E. Farver
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Patent number: 7255823Abstract: An encapsulation for an organic light emitting diode (OLED) (201) device is disclosed. The encapsulation includes a sealing dam (280) surrounding the cell region of the OLED device to support a cap. The sealing dam provides a sealing region between the edge of the cap and dam in which an adhesive is applied to seal the OLED device. The use of the sealing dam advantageously enables devices to be formed with narrower sealing widths.Type: GrantFiled: September 6, 2000Date of Patent: August 14, 2007Assignees: Institute of Materials Research and Engineering, Osram Opto Semiconductor GmbHInventors: Ewald Karl Michael Guenther, Mark Dai Joong Auch
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Patent number: 7255824Abstract: An apparatus for molding a plastic closure includes a male mold assembly including a forming pin and an outer pin sleeve which cooperate with a female mold for defining a mold cavity. To facilitate mechanical stripping of a molded closure from the forming pin, pressurized air is introduced into the molded closure through at least one air passageway which extends axially between the forming pin and pin sleeve. By outwardly expanding and forming the plastic closure during ejection from the forming pin, forces to which the closure is subjected during ejection are significantly reduced, thereby desirably reducing the amount of cooling of the closure that is required during the molding cycle prior to ejection. Significantly increased operating speeds for the compression molding apparatus can thus be achieved.Type: GrantFiled: March 23, 2005Date of Patent: August 14, 2007Assignee: Alcoa Closure Systems InternationalInventors: David Cerny, Ramesh Kamath, Mark Powell, Greg Mishler, Sohail Sadiq, David Oles, Lindsey Abney
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Patent number: 7255825Abstract: Materials and methods for freeform fabrication of a solid three-dimensional object are provided. At least one layer of support material and at least one layer of build material are dispensed onto a substrate. The support material includes at least one of water and a fusible water-containing substance and the build material is a substance other than water or a fusible, water-containing substance. After solidification, the at least one layer of support material is removed by an automated or manual process which includes washing with water at ambient temperature and/or causing the support material to undergo a phase change, to produce the solid three-dimensional object.Type: GrantFiled: March 10, 2004Date of Patent: August 14, 2007Assignee: Hewlett-Packard Development Company, L.P.Inventors: Jeffrey A. Nielsen, Vladek Kasperchik, Laura Kramer
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Patent number: 7255826Abstract: The invention relates to a container which is formed at the upper portion of the main body with the foldable portion having folding lines for easily folding the foldable portion. Processes for forming the container include a first step for forming a perform by injection molding and a second step for forming the finished product having the foldable portion by blow molding.Type: GrantFiled: October 25, 2004Date of Patent: August 14, 2007Inventor: Jung-Min Lee
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Patent number: 7255827Abstract: Novel blow cylinders use a retract fluid at a minimum pressure, located between a piston head and a wall of a cylinder body, to prevent the piston head from violently impacting the wall when the piston head is moved so that a blow needle engages a parison. The retract fluid at a minimum pressure is also used to move the piston head so that the blow needle disengages the parison.Type: GrantFiled: December 12, 2003Date of Patent: August 14, 2007Assignee: Graham Packaging Company, L.P.Inventors: Marshall Miller, Bernie Klingenmaier
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Patent number: 7255828Abstract: A method and apparatus for performing electromagnetic treatment on engineering materials and products and for improving processing technologies and service characteristics of the materials. The apparatus integrates electromagnetic treatment with a thermal analyzer and a control system. The apparatus allows for precise control of the operating parameters of an electromagnetic treatment process in order to render significant improvement in the materials and products metallurgical characteristics.Type: GrantFiled: December 5, 2003Date of Patent: August 14, 2007Inventors: Marcin Stanislaw Kasprzak, Wojciech Kasprzak, Jerzy H. Sokolowski
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Patent number: 7255829Abstract: A method and an apparatus for the thermal treatment of metallic workpieces with which gas quenching can be obtained that is low in distortion, even for workpieces with an undulating shape or workpieces that are projectingly stackable are provided. In accordance with the method, after being heated the workpieces are cooled in a quenching chamber with a quenching gas, whereby the quenching gas is intentionally caused to flow around the workpieces by means of guide channels that have a closed lateral surface and that enclose the workpieces along the direction of flow of the quenching gas. The apparatus comprises a quenching chamber in which the workpieces can be cooled with a quenching gas, and wherein guide channels are provided to ensure that the quenching gas flows around the workpieces, the guide channels having a closed lateral surface and enclosing the workpieces along the direction of flow of the quenching gas.Type: GrantFiled: August 30, 2000Date of Patent: August 14, 2007Assignee: Ipsen International GmbHInventors: Wolfgang Peter, Bernd Edenhofer, Jan-Willem Bouwman
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Patent number: 7255830Abstract: To make a three-dimensional object, an optical beam is first irradiated on a predetermined portion of a powder layer to form a sintered layer, which is then covered with a new powder layer. The optical beam is again irradiated on a predetermined portion of the new powder layer to form another sintered layer that has been united with the underlying sintered layer. These processes are repeatedly carried out to form a plurality of sintered layers united together. When the second lower density layer is formed on the first higher density layer, a powder material layer for the lower density layer is formed at a predetermined thickness so as to have a thickness suitable for sintering condition and then the powder material layer is sintered to form the lower density layer.Type: GrantFiled: September 29, 2003Date of Patent: August 14, 2007Assignee: Matsushita Electric Works, Ltd.Inventors: Satoshi Abe, Isao Fuwa, Hirohiko Togeyama, Norio Yoshida, Masataka Takenami, Shuushi Uenaga
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Patent number: 7255831Abstract: A tungsten oxide/titanium dioxide photocatalyst coating oxidizes contaminants in the air that adsorb onto the coating into water, carbon dioxide, and other substances. The tungsten oxide forms a monolayer on the titanium dioxide. When photons of the ultraviolet light are absorbed by the tungsten oxide/titanium dioxide photocatalyst coating, an electron is promoted from the valence band to the conduction band, producing a hole in the valence band. The holes in the valence band react with water applied on the tungsten oxide/titanium dioxide photocatalyst coating, forming reactive hydroxyl radicals. When a contaminant in the air is adsorbed onto the tungsten oxide/titanium dioxide photocatalyst, the hydroxyl radical attacks the contaminant, abstracting a hydrogen atom from the contaminant. The hydroxyl radical oxidizes the contaminant, producing water, carbon dioxide, and other substances. The tungsten oxide/titanium dioxide photocatalytic coating has low sensitivity to humidity variations.Type: GrantFiled: May 30, 2003Date of Patent: August 14, 2007Assignee: Carrier CorporationInventors: Di Wei, Timothy N. Obee, Stephen O. Hay, Thomas H. Vanderspurt, Wayde R. Schmidt, Joseph J. Sangiovanni
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Patent number: 7255832Abstract: Laminated test devices in which positive results are detected by the appearance of a symbol on the surface of the device due to a color change in an indicator in the device are improved by placing the indicator lamina on one side of a light-transmissive substrate sheet and a pigment lamina on the other side, the indicator lamina forming the icon and the pigment lamina forming the background, the pigment being the color of the indicator prior to the color change. This arrangement reduces false positive readings by obscuring the outlines of the symbol prior to the color change. False negative readings are reduced by further changes in the arrangement of the laminae.Type: GrantFiled: September 17, 2004Date of Patent: August 14, 2007Assignee: Quidel CorporationInventors: Paul J. Lawrence, Aulena Chaudhuri
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Patent number: 7255833Abstract: This invention provides an apparatus for rapidly heating and/or cooling a sample in a reaction vessel. In some embodiments, the apparatus includes optics for the efficient detection of a reaction product in the vessel. The invention also provides a reaction vessel having a reaction chamber designed for optimal thermal conductance and for efficient optical viewing of reaction products in the chamber.Type: GrantFiled: March 3, 2003Date of Patent: August 14, 2007Assignee: CepheidInventors: Ronald Chang, Lee A. Christel, Gregory T. A. Kovacs, William A. McMillan, M. Allen Northrup, Kurt E. Petersen, Farzad Pourahmadi, Steven J. Young, Robert Yuan, Douglas B. Dority
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Patent number: 7255834Abstract: A method and device are provided for dynamic flash combustion reaction connected with gas chromatography for the elemental analysis of C H N S O in an automatic elemental analyzer. A combustion reactor is provided with a sampling device and an oxygen feed line. Controlled volumes of oxygen are admitted with the oxygen feed line into the combustion reactor depending on the sample for the complete combustion thereof. A pneumatic circuit is provided, in which the oxygen feed line converges and the pneumatic circuit creates a continuous flow of a carrier gas that is able to carry the oxygen to the reactor and the gases of the combustion through the reactor, then through a gas chromatographic analyzer, and after their separation, into a thermal conductivity detector. An electronic apparatus with a data processor is provided for controlling the process systems. The difference in the pressure of the gas upstream and downstream of a restrictor or restriction is determined.Type: GrantFiled: November 22, 2002Date of Patent: August 14, 2007Assignee: Eurovector S.p.A.Inventors: Stefano Boursier Niutta, Leonardo Sisti
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Patent number: 7255835Abstract: Apparatus and method for acquiring an infrared spectrum of a sample having or suspected to have an amide I band, an amide II band, an amide III band, an amide A band, an OH stretching region or a combination thereof. A representative method includes providing a sample; providing an internal reflecting element (IRE) with a functionalized tip; contacting the sample with the IRE to form a sample-IRE interface; directing a beam of infrared (IR) radiation through the IRE under conditions such that the IR radiation interacts with the sample-IRE interface once; recording a reflectance profile over a range of preselected frequencies, whereby an infrared spectrum of the of a sample having or suspected of having an amide I band, an amide II band, an amide III band, an amide A band, an OH stretching region or a combination thereof, disposed in an aqueous solution is acquired.Type: GrantFiled: September 4, 2002Date of Patent: August 14, 2007Assignee: North Carolina State UniversityInventors: Stefan Franzen, Simon E. Lappi
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Patent number: 7255836Abstract: A device and method for quantifying an impurity in an input gas stream. The device and method employ a catalyst to convert the impurity to a detectable species in an output gas stream, and the concentration of the detectable species is then measured by means of a detector.Type: GrantFiled: March 13, 2003Date of Patent: August 14, 2007Assignee: Trustees of Princeton UniversityInventors: Kevin Lehmann, Yu Chen, Wen-Bin Yan
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Patent number: 7255837Abstract: An airtight configuration for keeping down the permeation of corrosive gas from silicone adhesive, and for preventing corrosive gas from entering the case. An electronic device mounted on vehicle. The electronic device has at least one of a portion connecting components, and a portion sealing the clearance or hole where exists in the electronic device. The at least one of the connection portion and the seal portion is constituted by using adhesive or sealant which has at least one of a function adsorbing corrosive gas and a function trapping corrosive gas with chemical reaction. A car-mounted electronic device characterized by reduced permeation of corrosive gas into a case and high reliability.Type: GrantFiled: September 20, 2002Date of Patent: August 14, 2007Assignees: Hitachi, Ltd., Hitachi Car Engineering Co., Ltd.Inventors: Hiroyuki Abe, Shinya Igarashi
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Patent number: 7255838Abstract: An air filter for an internal combustion engine having a rigid type ceramic filter element made by foaming oxygen-rich ceramic powder for creating a plurality of pass-through holes. In this way, the incoming air obtains a thorough contact with the oxygen-rich powder. Meanwhile, the material of the oxygen-rich ceramic releases negative ions to activate the air entering into the internal combustion engine. Moreover, nano-sized platinum black is coated to the surface of the pass-through holes of the ceramic filter element. So, the incoming air passing through the pass-through holes of the ceramic filter element is catalyzed in chemical reactions to divide the water molecule cluster into smaller particles. Meanwhile, the freedom of water molecule is increased to permit an instant decomposition of oxygen and nitrogen molecules, a complete combination with the fuel injected into the internal combustion engine, and a thorough mixing and a better combustion efficiency.Type: GrantFiled: September 21, 2004Date of Patent: August 14, 2007Inventors: Andy Yuan, Huan-Pien Li
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Patent number: 7255839Abstract: A device for treating a substance containing at least one undesirable organism, using a pulsed electrical field. The device includes at least one treatment zone of the substance located within a passage zone associated with the substance. Each treatment zone is only partially located within the associated passage zone. The device also includes a mechanism to create movement for displacing each treatment zone of the substance in the entire associated passage zone.Type: GrantFiled: October 16, 2002Date of Patent: August 14, 2007Assignee: Commissariant a l'Energie AtomiqueInventors: Daniel Chatroux, Philippe Nouvel, Julien Scordia
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Patent number: 7255840Abstract: An autothermal reactor and method for producing synthesis gas in which a heated oxygen containing stream is expanded into a mixing chamber to entrain a hydrocarbon containing stream to form a reactant stream without reaction of the oxygen and hydrocarbon contents of the streams. The reactant stream is reacted in a series of sequential catalytic reaction zones to react the hydrocarbon and oxygen contained in the reactant stream to form the synthesis gas. The sequential catalytic reaction zones are configured such that an initial partial oxidation reaction occurs that is followed by endothermic reforming reactions having ever decreasing temperatures. The sequential catalytic reaction zones in which the endothermic reforming reactions occur contain a precious metal catalyst supported on ceramic supports that have successively greater surface areas to compensate for the temperature decrease while remaining stable and without a transform in state.Type: GrantFiled: June 26, 2003Date of Patent: August 14, 2007Assignee: Praxair Technology, Inc.Inventors: Vasilis Papavassiliou, Minish Mahendra Shah, Thomas John Bergman, Jr.
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Patent number: 7255841Abstract: A method of producing sodium bicarbonate having a high degree of purity and obtaining a net reduction in effluent waste water, as compared to prior processes, when starting from trona ore is disclosed. The process entails utilizing the waste-water effluent stream from the conversion of trona ore to sodium carbonate as the feed for the conversion of sodium carbonate to sodium bicarbonate.Type: GrantFiled: September 29, 2003Date of Patent: August 14, 2007Assignee: Church & Dwight Co., Inc.Inventor: Andrew D. Kurtz
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Patent number: 7255842Abstract: A new method for the removal of environmental compounds from gaseous streams, in particular, flue gas streams. The new method involves first oxidizing some or all of the acid anhydrides contained in the gas stream such as sulfur dioxide (SO2) and nitric oxide (NO) and nitrous oxide (N2O) to sulfur trioxide (SO3) and nitrogen dioxide (NO2). The gas stream is subsequently treated with aqua ammonia or ammonium hydroxide which captures the compounds via chemical absorption through acid-base or neutralization reactions. The products of the reactions can be collected as slurries, dewatered, and dried for use as fertilizers, or once the slurries have been dewatered, used directly as fertilizers. The ammonium hydroxide can be regenerated and recycled for use via thermal decomposition of ammonium bicarbonate, one of the products formed. There are alternative embodiments which entail stoichiometric scrubbing of nitrogen oxides and sulfur oxides with subsequent separate scrubbing of carbon dioxide.Type: GrantFiled: September 22, 2003Date of Patent: August 14, 2007Assignee: United States of America Department of EnergyInventors: James T. Yeh, Henry W. Pennline
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Patent number: 7255843Abstract: A fumed-silica, which can make a slurry having sufficient wettability to a polar liquid, excellent dispersibility, and low viscosity even in the high concentration, and a slurry thereof. A fumed-silica and its slurry are provided, wherein the water content is controlled so that a weight loss after drying Y, and a dynamic wetting rate to water Z, have specified values.Type: GrantFiled: December 23, 2002Date of Patent: August 14, 2007Assignee: Nippon Aerosil Co., Ltd.Inventors: Hitoshi Kobayashi, Masamichi Murota, Hirokuni Shirono
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Patent number: 7255844Abstract: A method of producing high quality GaN powder by combining high purity gallium and high purity ammonia in a tube reactor under controlled conditions. A reaction between the ammonia and gallium under the controlled conditions produces a porous gallium melt and to a full reaction, yielding high purity crystalline GaN powders with a stoichiometric nitrogen concentration and a hexagonal wurtzite structure.Type: GrantFiled: November 24, 2004Date of Patent: August 14, 2007Assignee: Arizona Board of RegentsInventors: Fernando A. Ponce, Rafael Garcia, Abigail Bell, Alan C. Thomas, Michael R. Stevens
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Patent number: 7255845Abstract: This invention relates to a process for conducting an equilibrium limited chemical reaction in a single stage process channel. A process for conducting a water shift reaction is disclosed. A multichannel reactor with cross flow heat exchange is disclosed.Type: GrantFiled: August 11, 2005Date of Patent: August 14, 2007Assignee: Velocys, Inc.Inventors: Anna Lee Tonkovich, Wayne W. Simmons, Kai Tod Paul Jarosch, Terry Mazanec, Eric Daymo, Ying Peng, Jennifer Lynne Marco
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Patent number: 7255846Abstract: The present invention provides methods for synthesis of IV–VI nanostructures, and thermoelectric compositions formed of such structures. In one aspect, the method includes forming a solution of a Group IV reagent, a Group VI reagent and a surfactant. A reducing agent can be added to the solution, and the resultant solution can be maintained at an elevated temperature, e.g., in a range of about 20° C. to about 360° C., for a duration sufficient for generating nanoparticles as binary alloys of the IV–VI elements.Type: GrantFiled: May 3, 2005Date of Patent: August 14, 2007Assignees: Massachusetts Institute of Technology, The Trustees of Boston CollegeInventors: Zhifeng Ren, Gang Chen, Bed Poudel, Shankar Kumar, Wenzhong Wang, Mildred Dresselhaus
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Patent number: 7255847Abstract: This invention relates to methods of making single phase nanocrystalline titanium dioxide. It is hereby provided a method for preparing single-phase anatase type titanium dioxide photocatalyst having a particle size of nano level at near room temperatures without the need for a sintering process at high temperatures.Type: GrantFiled: November 16, 2004Date of Patent: August 14, 2007Assignee: The Hong Kong Polytechnic UniversityInventors: Walid Abdelhamid Daoud, John Haozhong Xin, Kaihong Qi
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Patent number: 7255848Abstract: A process for producing hydrogen from ethanol or other alcohols. The alcohol, optionally in combination with water, is contacted with a catalyst comprising rhodium. The overall process is preferably carried out under autothermal conditions.Type: GrantFiled: September 30, 2003Date of Patent: August 14, 2007Assignee: Regents of the Univeristy of MinnesotaInventors: Gregg A. Deluga, Lanny D. Schmidt
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Patent number: 7255849Abstract: EMM-3 (ExxonMobil Material number 3) is a new crystalline microporous material with a framework of tetrahedral atoms connected by atoms capable of bridging the tetrahedral atoms, the tetrahedral atom framework being defined by the interconnections between the tetrahedrally coordinated atoms in its framework. EMM-3 can be prepared in aluminophosphate (AlPO) and metalloaluminophosphate (MeAPO) compositions with the hexamethonium template. It has a unique X-ray diffraction pattern, which identifies it as a new material. EMM-3 is stable to calcination in air, absorbs hydrocarbons, and is catalytically active for hydrocarbon conversion.Type: GrantFiled: June 8, 2004Date of Patent: August 14, 2007Assignee: ExxonMobil Research and Engineering CompanyInventors: Karl G. Strohmaier, Arthur W. Chester, William R. Harrison, James C. Vartuli
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Patent number: 7255850Abstract: The present invention relates to biochemical methods for determining reverse cholesterol transport. Specifically, the rates of the two arms of reverse cholesterol transport (HDL or first arm and post-HDL or second arm) are obtained by measuring the flow of unlabeled cholesterol from tissues into plasma HDL and from plasma HDL to bile acids.Type: GrantFiled: September 15, 2003Date of Patent: August 14, 2007Assignee: The Regents of the University of CaliforniaInventor: Marc K. Hellerstein
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Patent number: 7255851Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: June 2, 2005Date of Patent: August 14, 2007Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 7255852Abstract: Precipitated silica comprising porous silica particles having a cumulative surface area for all pores having diameters greater than 500 ? of less than 8 m2/g, as measured by mercury intrusion, and a percentage cetylpyridinium chloride (% CPC) Compatibility of greater than about 55%. The precipitated silica product is especially well-adapted for use in dentifrices containing cetylpyridinium chloride, which do not attach to the low surface area silica product in a meaningful level and thus remain available for antimicrobial action. Processes for making the silica product are also provided.Type: GrantFiled: October 3, 2003Date of Patent: August 14, 2007Assignee: J.M. Huber CorporationInventors: Karl W. Gallis, Mark E. Wozniak, John A. Kostinko
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Patent number: 7255853Abstract: Cosmetic compositions for topical use for protecting the skin and the hair, containing, in a cosmetically acceptable support, at least one compound of formula (1) or (2) in which X1 represents R3—(C?O)—, R3—SO2— or R3—O—(C?O)—, X2 represents —(C?O)—R?3—(C?O), —SO2—R?3—SO2— or —(C?O)—O—R?3—O—(C?O)—, Y represents —(C?O)—R4 or —SO2R5, R2 represents a C1-8 alkyl group, n is 0, 1 or 2, R3 represents C1-30 alkyl or C3-30 alkenyl, R?3 represents a single bond or a divalent C1-30 alkylene or C3-30 alkenylene radical, R4 represents —OR6 or —NHR6, R5 represents C1-30 alkyl or a phenyl nucleus, R6 represents C1-30 alkyl or C3-30 alkenyl, and novel compounds of formula (2).Type: GrantFiled: March 19, 2004Date of Patent: August 14, 2007Assignee: L'OrealInventors: Hervé Richard, Bernadette Luppi
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Patent number: 7255854Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signaling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.Type: GrantFiled: April 23, 1999Date of Patent: August 14, 2007Assignee: Biogen, Inc.Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne Mackay
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Patent number: 7255855Abstract: The present invention relates to a method for expressing each of peptide antibiotics P5 3 and Ana13 35 having amphiphilicity and showing antibacterial, antifungal and anticancer activities 61, 63, 65, 67, 69, 71, on the microbial surface, using a vector containing outer membrane protein genes (pgsBCA) that are derived from Bacillus sp. strains and involved in the synthesis of poly-gamma-glutamate. Moreover, the present invention relates to lactic acid-forming bacteria having each of the peptide antibiotics P5 15 and Ana13 43 expressed on their surface, and the use thereof. According to the present invention, the peptide antibiotics can be expressed on the surface of various microorganisms transformed with the surface expression vectors. The inventive method for the surface expression of the peptide antibiotics allows the peptide antibiotics to be mass-produced without a purification process. Thus, the inventive method has very high industrial applicability.Type: GrantFiled: February 27, 2004Date of Patent: August 14, 2007Assignee: Bioleaders CorporationInventors: Moon-Hee Sung, Seung-Pyo Hong, Jong-Su Lee, Chang-Min Jung, Kyung-Soo Hahm, Dong-Gun Lee, Yoon Kyung Park, Chul-Joong Kim, Ha-Ryoung Poo
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Patent number: 7255856Abstract: Described are methods of treating and preventing conditions associated with a loss of elastic fibers. Also provided herein are methods of screening for agents useful in treating such conditions, and animal models of conditions associated with a loss of elastic fibers.Type: GrantFiled: January 24, 2005Date of Patent: August 14, 2007Assignee: Massachusetts Eye & Ear InfirmaryInventors: Tiansen Li, Xiaoqing Liu
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Patent number: 7255857Abstract: Described are methods of treating and preventing conditions associated with a loss of elastic fibers. Also provided herein are methods of screening for agents useful in treating such conditions, and animal models of conditions associated with a loss of elastic fibers.Type: GrantFiled: September 26, 2005Date of Patent: August 14, 2007Assignee: Massachusetts Eye & Ear InfirmaryInventors: Tiansen Li, Xiaoqing Liu
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Patent number: 7255858Abstract: The present invention is directed to a composition and method for enhancing the complement-mediated cytotoxicity of therapeutic antibodies for their target cells (i.e. those cells displaying the target epitope). More particularly the present invention enhances the efficacy of such therapies by providing a supplemental source of complement.Type: GrantFiled: August 9, 2002Date of Patent: August 14, 2007Assignee: University of Virginia Patent FoundationInventors: Ronald P. Taylor, Margaret A. Lindorfer, Michael D. Solga, Adam Kennedy
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Patent number: 7255859Abstract: The invention concerns monoclonal antibodies against the epitope YPYDVPDYA (SEQ ID NO: 1) which is derived from the haemagglutinin of the human influenza virus and are suitable for the detection and isolation of native haemagglutinin of the human influenza virus, of modified haemagglutinin or of haemagglutinin fusion proteins and have an affinity of >108 M?1, in particular of 109 to 1010 M?1.Type: GrantFiled: October 20, 1997Date of Patent: August 14, 2007Assignee: Roche Diagnostics GmbHInventors: Thomas Emrich, Matthias Hinzpeter, Michael Grol
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Patent number: 7255860Abstract: The invention features methods and compositions for preventing or treating post-surgical pain by administering an anti-NGF antagonist antibody.Type: GrantFiled: October 8, 2003Date of Patent: August 14, 2007Assignee: Rinat Neuroscience Corp.Inventors: David L. Shelton, German J. Vergara
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Patent number: 7255861Abstract: The present invention provides isolated peptides relating to the autoimmune diseases pemphigus vulgaris and multiple sclerosis. The peptides relating to pemphigus vulgaris are self epitopes and those relating to multiple sclerosis are foreign antigens derived from human pathogens which are implicated in the aetiology and remissions of the disease. Pharamaceutical preparations for tolerizing and/or immunizing individuals are provided as well as methods relating thereto. Methods are provided for identifying other self and non-self epitopes involved in human autoimmune disease and similar pharamaceutical preparations and methods of use for these epitopes are also provided.Type: GrantFiled: November 5, 1997Date of Patent: August 14, 2007Assignee: President and Fellows of Harvard CollegeInventors: Jack L. Strominger, Kai W. Wucherpfennig
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Patent number: 7255862Abstract: Recombinants containing and expressing lentivirus, retrovirus or immunodeficiency virus DNA and methods for making and using the same are disclosed and claimed. In an exemplified embodiment, attenuated recombinant viruses containing DNA encoding a feline immunodeficiency virus epitope such as an antigen, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinants can be NYVAC or ALVAC recombinants. The DNA can encode at least one of: Env, Gag, Pol, or combinations thereof such as Gag and Pol or protease or Env, Gag and Pol or protease. The recombinants and gene products therefrom and antibodies generated by them have several preventive, therapeutic and diagnostic uses. DNA from the recombinants are useful as probes or, for generating PCR primers or for immunization.Type: GrantFiled: November 14, 1996Date of Patent: August 14, 2007Assignee: Connaught Technology CorporationInventors: James Tartaglia, Enzo Paoletti
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Patent number: 7255863Abstract: The present invention provides methods for eliciting an immune response against Group A streptococci, comprising use of recombinant fusion polypeptides, and compositions thereof, that include a multivalent immunogenic portion of at least two immunogenic polypeptides from Group A streptococci M proteins (which are capable of stimulating a protective immune response against Group A streptococci), and a reiterated polypeptide from the immunogenic portion carboxy-terminal to the immunogenic portion, wherein the carboxy-terminal polypeptide is not required to stimulate an immune response against Group A streptococci.Type: GrantFiled: January 16, 2004Date of Patent: August 14, 2007Assignee: University of Tennessee Research FoundationInventor: James B Dale
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Patent number: 7255864Abstract: A diagnostic reagent for hepatitis C virus infection obtained by sensitizing a solid phase with HCV antigen and a conjugated antigen prepared by chemical bonding of HCV antigen and a carrier protein, and a method of diagnosing hepatitis C virus infection, which comprises adding the diagnostic reagent for hepatitis C virus infection to a sample, and measuring the degree of agglutination of carrier particles as the solid phase. The diagnostic reagent and the method of diagnosis enable many samples to be measured with higher sensitivity and rapidity.Type: GrantFiled: May 10, 2005Date of Patent: August 14, 2007Assignee: Sysmex CorporationInventors: Yoichi Takahama, Junichi Shiraishi
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Patent number: 7255865Abstract: Methods for treating conditions in an animal or human subject. The conditions may be pain, skeletal muscle conditions, smooth muscle conditions, glandular conditions and cosmetic conditions. The methods comprise the step of administering a Clostridium neurotoxin component or Clostridium neurotoxin component encoding DNA to the subject using a needleless syringe.Type: GrantFiled: January 17, 2002Date of Patent: August 14, 2007Assignee: Allergan, Inc.Inventor: Patricia S. Walker
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Patent number: 7255866Abstract: Methods for treating fibromyalgia by administering a therapeutically effective amount of a botulinum toxin to a patient with fibromyalgia.Type: GrantFiled: September 18, 2003Date of Patent: August 14, 2007Assignee: Allergan, Inc.Inventor: Martin A. Voet
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Patent number: 7255867Abstract: Effective stimulation of immune responses is achieved through the use of a group A streptococcal antigen combined with proteosome adjuvant. The compositions are provided in particular for intranasal administration. The vaccine compositions are provided for use in inducing an immune response in an individual for the treatment or prophylaxis of group A streptococcal infection in an individual, preferably via prevention or reduction of colonisation of the throat following intranasal administration.Type: GrantFiled: November 13, 2003Date of Patent: August 14, 2007Assignees: ID Biomedical Corporation of Quebec, The Council of the Queensland Institute of Medical ResearchInventors: George H Lowell, George L White, Michael R Batzloff, David S Burt, Tomas B Leanderson, Michael F Good
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Patent number: 7255868Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.Type: GrantFiled: June 21, 2002Date of Patent: August 14, 2007Assignee: Dynavax Technologies CorporationInventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
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Patent number: 7255869Abstract: Disclosed is anhydrous cosmetic compositions comprising: (a) a hydrophobic polyol; and (b) a hydrophilic polyol; which can provide improved conditioning benefits such as moisturizing benefit, and also can provide improved deposition of oily conditioning agents when included in the compositions.Type: GrantFiled: October 18, 2002Date of Patent: August 14, 2007Assignee: The Procter & Gamble CompanyInventors: Mikio Uchida, Misa Azuma, Kumiko Nakajima
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Patent number: 7255870Abstract: A composition containing an aqueous phase dispersed in an oily phase, at least one emulsifier with an HLB value ranging from 1 to 8, at least one organic powder, and, in the oily phase at least one semicrystalline polymer with organic structure that is solid at room temperature and that has a melting point of less than 70° C., the said polymer comprising a) a polymer skeleton and b) at least one crystallizable organic side chain and/or at least one crystallizable organic sequence forming part of the said polymer skeleton, the polymer having a number-average molecular weight of greater than 2,000. This composition can especially constitute a cosmetic cream, having a very pleasant texture when applied to the skin, or a stick, especially a makeup-removing stick.Type: GrantFiled: January 21, 2003Date of Patent: August 14, 2007Assignee: L'OrealInventors: Paula Lennon, Raluca Lorant
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Patent number: 7255871Abstract: A nanotube mat is provided with an array of conduits to support, direct growth, select or interface one or more biological cells or cell processes. The carbon nanotube mat provides mechanical stability, is biocompatible, will support cell growth, can desirably be derivatized with growth factors, molecules, nutrients, inhibitory factors, ligands, transduction molecules or morphogenic factors, and would allow the formation of conduits to guide cells and cell extensions to be hosted or grown. The conduits could take any size or shape to support, direct growth, select or interface one or more cells or processes. In general the conduits could be channels, discontinuous channels, tapered channels or walls. The nanotube mat could be used to interface biological cells with other cells, tissue or structures that have electrical, mechanical, magnetic means, or optical means. The nanotube mat could also incorporate chemicals, analytes, drugs, lips, carbohydrates, secretory products or the like.Type: GrantFiled: May 6, 2003Date of Patent: August 14, 2007Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Philip Huie, Jr., Harvey A. Fishman