Patents Issued in November 6, 2007
  • Composition containing polymer having ionic functional group, ink composition, and image-forming method and image-forming apparatus employing the ink composition
    Patent number: 7291668
    Abstract: The present invention provides an ink composition containing a pigment dispersed uniformly in a solvent and a block polymer having an ionic functional group, an image-forming method and an image-forming apparatus employing the ink composition. The composition comprises a pigment, a solvent and a polymer having an ionic functional group, an acid residue, or a base residue at the terminal. The polymer having an ionic functional group, an acid residue, or a base residue at the terminal is a block polymer of ABX type having A, B, and X segments, wherein A and B are respectively a block segment having a vinyl ether structure as the repeating unit, and X is a terminal segment having an ionic functional group, an acid residue, or an base residue.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: November 6, 2007
    Assignee: Canon Kabushiki Kaisha
    Inventors: Masayuki Ikegami, Koichi Sato, Ikuo Nakazawa, Sakae Suda
  • Stabilized polyolefin compositions
    Patent number: 7291669
    Abstract: Polyolefin compositions comprising a particular hindered phenolic antioxidant selected from the group consisting of tris(3,5-di-tert-butyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris-(3,5-di -tert-butyl-4-hydroxybenzyl)-2,4,6-trimethylbenzene and the calcium salt of the monoethyl ester of 3,5-di-tert-butyl-4-hydroxybenzylphosphonic acid, an oligomeric sterically hindered amine light stabilizer, a hydroxylamine stabilizer or trialkylamine N-oxide stabilizer, and, optionally, an organic phosphorus stabilizer, are effectively stabilized against degradation upon melt processing, long term heat aging, and exposure to combustion products of natural gas.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: November 6, 2007
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: James H. Botkin, Urs L. Stadler
  • Cross-linking silicone elastomers, method for the production thereof, and use of the cross-linkable masses
    Patent number: 7291670
    Abstract: Addition crosslinkable organopolysiloxane compositions employ specific rhodium catalysts. The compositions exhibit storage stability and crosslink effectively to provide highly transparent and colorless organopolysiloxane elastomers.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: November 6, 2007
    Assignee: Wacker Chemie AG
    Inventors: Armin Fehn, Jürgen Weidinger, Adelheid Dürnberger
  • Thermoconductive silicone composition
    Patent number: 7291671
    Abstract: A thermoconductive silicone composition comprising: (A) an organopolysiloxane (excluding component (C)), (B) a thermoconductive filler, and (C) at least two organopolysiloxanes as defined by the following general formula that have different values for the subscript n (I), wherein each R1 is independently selected from monovalent hydrocarbon groups; R2 is an oxygen atom or divalent hydrocarbon group; R3 is an alkyl, alkoxyalkyl, alkenyl, or acyl; n is an integer from 5 to 100; and a is an integer from 1 to 3
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: November 6, 2007
    Assignee: Dow Corning Toray Company, Ltd.
    Inventor: Hiroshi Fukui
  • Paste composition and uses thereof
    Patent number: 7291672
    Abstract: The paste composition of the present invention is a paste composition comprising (i) a polyurethane resin which comprises (a) a recurring unit represented by the formula (1) and (b) a recurring unit represented by the formula (2), a molar fraction of said recurring unit (a) being in the range of 0.35 to 0.99, a molar fraction of said recurring unit (b) being in the range of 0.01 to 0.65, the total of both the molar fractions being 1, (ii) a solvent and (iii) a powder. By the use of the paste composition, dielectric layers, sealing products, barrier ribs, phosphors, etc. can be favorably formed.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: November 6, 2007
    Assignee: Mitsu Takeda Chemicals, Inc.
    Inventors: Daiki Taneichi, Manabu Tsuruta, Masahiko Mitsuduka
  • Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
    Patent number: 7291673
    Abstract: The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: November 6, 2007
    Assignees: Eidgenossiche Technische Hochschule Zurich, Universitat Zurich
    Inventors: Jeffrey A. Hubbell, Donald Elbert, Ronald Schoenmakers
  • Superabsorbent polymer
    Patent number: 7291674
    Abstract: The invention relates to a superabsorbent polymer comprising a composition comprising a polymeric resin composition comprising from about 55 to about 99.9 wt. % of polymerizable unsaturated acid group containing monomers, from about 0.001 to about 5.0 wt. % of internal crosslinking agent and from 0 to 25 wt % of a preneutralizing agent; wherein the polymeric resin composition is preneutralized from 0 to about 50 mole %; and a water swellable, water-insoluble aminopolysaccaride polymer wherein when the superabsorbent polymer is contacted with an aqueous solution, the polymeric resin composition is neutralized by the aminopolysaccaride polymer so that the superabsorbent polymer has a degree of neutralization of about 20 mole % or more than the preneutralization degree of the polymeric resin composition.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: November 6, 2007
    Assignee: Stockhausen, Inc.
    Inventors: Seungkoo Kang, Scott J. Smith
  • Golf ball rubber compositions and golf balls
    Patent number: 7291675
    Abstract: A rubber composition for a one-piece golf ball or for a solid core of a solid golf ball having a multilayer construction in which the core is enclosed directly, or with an intermediate layer, by a cover includes (a) 100 parts by weight of a base rubber, (b) 10 to 60 parts by weight of a co-crosslinking agent, (c) 5 to 80 parts by weight of an inorganic filler, (d) 0.1 to 5 parts by weight of an organic peroxide, (e) 0.05 to 5 parts by weight of an organosulfur compound, (f) 0.05 to 5 parts by weight of sulfur, and (g) 1 to 10 parts by weight of a binary copolymer consisting of a polyolefin component and a polyamide component. Golf ball rubber compositions and golf balls made using such compositions have a good resilience and excellent durability.
    Type: Grant
    Filed: March 1, 2005
    Date of Patent: November 6, 2007
    Assignee: Bridgestone Sports Co., Ltd.
    Inventors: Atsushi Nanba, Jun Shindo
  • Polyolefin composition with improved abrasion resistance
    Patent number: 7291676
    Abstract: A composition comprising: (I) 55 to 95% by weight of an heterophasic polyolefin composition comprising 8 to 50% by weight of a crystalline propylene polymer fraction and 50 to 92% by weight of an elastomeric propylene fraction; (II) 2 to 20% by weight of an oxidized polyethylene wax having an acid number of 5 to 35 mg KOHIg, a molecular weight Mn of 1,000 to 100,000, and a melting point comprised between 92° C. and 140° C.; and (III) 3 to 25% by weight of a styrene block copolymer.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: November 6, 2007
    Assignee: Basell Poliolefine Italia S.p.A.
    Inventor: Dominic A. Berta
  • Adherent, modified thermoplastic elastomeric blends, articles, and methods
    Patent number: 7291677
    Abstract: A thermoplastic elastomer that is adherent to polar materials may be made from a dynamically vulcanized blend of propylene resin, ethylene/alpha-olefin/non-conjugated diene elastomers, and a bonding agent via a curing system containing a free radical initiator, at least one co-agent including multifunctional acrylates containing at least two acrylate groups, multifunctional maleimides containing at least two imide groups, or mixtures of both, where the elastomer gel content in the modified blend is at least about 97 percent. Reaction mixtures, articles made therefrom, and methods of dynamically vulcanizing are also disclosed.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: November 6, 2007
    Assignee: Solvay Engineered Polymers, Inc.
    Inventors: Kevin Cai, Anthony Nguyen, Charles G. Reid
  • Fluororesin composition, process for preparing the same and cable coated with the same
    Patent number: 7291678
    Abstract: The present invention provides a fluororesin composition, which is excellent in moldability and crack resistance, a process for preparing the composition and a cable evenly coated with the composition. Specifically, the present invention provides a fluororesin composition wherein polytetrafluoroethylene is compounded to a terpolymer comprising tetrafluoroethylene, hexafluoropropylene and perfluoroalkyl vinylether. Also, the present invention provides a process for preparing the composition which comprises kneading with a multi-screw kneader. Furthermore, the present invention provides a cable which is coated with the resin.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: November 6, 2007
    Assignee: Daikin Industries, Ltd.
    Inventors: Masayuki Namimatsu, Yoshiyuki Hiraga, Yoshiyuki Takase, Tadahiro Yabu
  • Recyclable polymer and process for production thereof
    Patent number: 7291679
    Abstract: A novel resin is provided which is renewable with less energy. A process for renewing the resin is also provided. The present invention includes a polymer having the repeating unit represented by Structural Formula (1) below, and a process for producing the polymer: [—P1—R—]n (1). In the formula, P1 indicates an addition polymer moiety having a continuous hydrocarbon chain as the skeleton containing no condensation system, and is a polymer or oligomer prepared by addition polymerization of one or more monomers having a double bond; R indicates a linking group constituted of a condensation system for linking the polymer moieties P; and n is a number of repeating units and is an integer of 2 or more.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: November 6, 2007
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroshi Maehara, Chieko Mihara, Yoshihiko Kikuchi
  • Metal catalyst and hydrogenation method employing the same
    Patent number: 7291680
    Abstract: A metal catalyst for hydrogenating unsaturated carbon-carbon bonds of copolymer is provided. The metal catalyst is a bimetallic complex comprising iridium and ruthenium. The metal catalyst has a formula comprising M1aM2bXm(L1)n, wherein the M1 is iridium, M2 is ruthenium; X is hydrogen, chlorine, bromine, iodine or pseudo halide; L1 is phosphine, bisphosphine, arsane or organic with nitrogen, sulfur and oxygen.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: November 6, 2007
    Assignee: Industrial Technology Research Institute
    Inventors: Kuo-Chen Shih, Hung-Yu Chen, Tsai-Tien Su
  • Polyisobutenamines
    Patent number: 7291681
    Abstract: Polyisobutenamines of the formula I: R—X??(I) where R is a polyisobutenyl radical having a number average molecular weight Mn of from 500 to 1500 and a polydispersity Mw/ Mn of less than 1.4 and X is an organic radical having amino groups, are prepared and are used as detergent additives in fuel compositions. Additive concentrates contain at least one polyisobutenamine in an amount of from 0.1 to 80% by weight.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: November 6, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans Peter Rath, Arno Lange, Dietmar Posselt
  • Method of producing comb or star copolymers using epoxy-functionalized nitroxylethers
    Patent number: 7291682
    Abstract: The present invention provides a method of forming comb or star copolymers. The comb or star copolymers are useful in surface modification of thermoplastic materials or as surfactants. The method is aimed at attaching a polymeric side chain differing in polarity and chemical structure from the backbone and forming a comb or star copolymer structure. In particular the process comprises polymerizing in a first step a polymer backbone from epoxy and nitroxylether group containing monomers and in a second step polymerizing under controlled radical conditions a comb or star structure onto this backbone.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: November 6, 2007
    Assignee: Ciba Specialty Chemicals Corp.
    Inventors: Wiebke Wunderlich-Wippert, Rudolf Pfaendner, Francesco Fuso, Jochen Fink
  • Compatible blends of thermoplastic molding compositions
    Patent number: 7291683
    Abstract: The present invention relates to compatible blends of, per se incompatible, thermoplastic molding compositions, to methods for the production thereof, and to the use of the blends according to the present invention to produce films, fibers and molded articles.
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: November 6, 2007
    Assignee: Rhein Chemie Rheinau GmbH
    Inventors: Heiko Tebbe, Volker Müller
  • Resin composition for encapsulating semiconductor chip and semiconductor device therewith
    Patent number: 7291684
    Abstract: An epoxy resin composition for encapsulating a semiconductor chip, which has good flowability without deterioration in curability. Specifically, a resin composition is disclosed for encapsulating a semiconductor chip containing a phenol aralkyl type epoxy resin containing biphenylene structure(A), a phenol aralkyl type resin containing phenylene or biphenylene structure (B), an inorganic filler (C) and a curing accelerator (D) as main components, further containing a silane coupling agent (E) in 0.01 wt % to 1 wt % both inclusive of the total amount of the epoxy resin composition and a Compound (F) containing two hydroxyl groups combined with each of adjacent carbon atoms on a naphthalene ring in more than or equal to 0.01 wt % of the total amount of the epoxy resin composition.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: November 6, 2007
    Assignee: Sumitomo Bakelite Co., Ltd.
    Inventors: Kuniharu Umeno, Shigehisa Ueda
  • Process for producing low polymer of ?-olefin
    Patent number: 7291685
    Abstract: There is disclosed a process for producing an ?-olefin oligomer by subjecting an ?-olefin to oligomerization reaction in the presence of a catalyst and an organic solvent which comprises the step of spraying a solvent containing the organic solvent in the form of a linear or bar-like pressure fluid toward a wall surface of a vapor phase portion of a reactor from a nozzle fitted within a space of the vapor phase portion of the reactor to conduct the oligomerization reaction while cleaning the wall surface of the vapor phase portion of the reactor. In the production process of the present invention, it is possible to effectively prevent deposition of polymers onto the wall surface of the vapor phase portion of the reactor and stably operate the reactor for a long period of time.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: November 6, 2007
    Assignee: Idemitsu Kosan Co. Ltd.
    Inventors: Ryoichi Kobayashi, Shigeki Kura
  • Method of producing polymer network
    Patent number: 7291686
    Abstract: Process for the preparation of a polymeric network, in which (i) one or more polymers are made available which can be crosslinked with one another intramolecularly or intermolecularly or intra- and intermolecularly by covalent or non-covalent bonding, (ii) the conformation of at least one of the polymers is adapted to at least one template compound with obtainment of at least one preferred conformation of the at least one polymer, (iii) at least one of the preferred conformations obtained according to (ii) is fixed by crosslinkage.
    Type: Grant
    Filed: November 26, 1999
    Date of Patent: November 6, 2007
    Assignee: Dr. Gottschall Instruction Gesellschaft fur Technische Chromatographie mbH
    Inventor: Klaus Gottschall
  • Catalyst system for synthesizing rubbery polymers having a high trans microstructure content
    Patent number: 7291687
    Abstract: The present invention is directed to a catalyst system for synthesizing rubbery polymers, such as polybutadiene rubber and styrene-butadiene rubber, having a high trans microstructure. The catalyst system, in one embodiment, includes (a) a barium salt of an alcohol that is soluble in a hydrocarbon solvent, and (b) an organomagnesium compound. In one example, the alcohol is a primary or secondary alcohol. The catalyst system can further optionally include an alkali metal alkoxide, an organolithium compound, an amine compound, or mixtures thereof.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: November 6, 2007
    Assignee: The Goodyear Tire and Rubber Company
    Inventors: Adel Farhan Halasa, Laurie Elizabeth Austin, Wen-Liang Hsu
  • Fluoroacrylate-mercaptofunctional copolymers
    Patent number: 7291688
    Abstract: A copolymer comprises repeating units derived from at least one co-reactant comprising two or more mercapto functional groups, and repeating units derived from a fluoroacrylate comprising the reaction product of: (a) at least one fluorochemical alcohol represented by the formula: C4F9—X—OH wherein: R=hydrogen or an alkyl group of 1 to 4 carbon atoms, m=2 to 8, Rf=CnF2n+1, n=1 to 5, y=0 to 6, and q=1 to 8; (b) at least one unbranched symmetric diisocyanate; and (c) at least one hydroxy-terminated alkyl (meth)acrylate or 2-fluoroacrylate monomer having 2 to about 30 carbon atoms in its alkylene portion.
    Type: Grant
    Filed: December 28, 2004
    Date of Patent: November 6, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Zai-Ming Qiu, John C. Clark, Ramesh C. Kumar
  • Thermally stable low dielectric norbornene polymers with improved solubility and adhesion property
    Patent number: 7291689
    Abstract: The present invention provides norbornene-based copolymers for which one monomer is at least selected from a group consisting of norbornene and dicyclopentadiene, and the other from norbornene-based comonomers of Formula 1 shown below: In Formula 1, R1, R2 and a are defined in this specification. The present invention provides insulating elements for multi-chip packages and antireflection films for the exposure process of semiconductor fabrication using said norbornene-based copolymers. Norbornene-based copolymers according to the present invention have low dielectric constant as well as high thermal stability and excellent solubility to various organic solvents.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: November 6, 2007
    Assignee: Seoul National University Industry Foundation
    Inventors: Jin Kyu Lee, Dong Woo Yoo, Seung Jae Yang, Kook Heon Char, Joo Hyeon Park
  • Process for production of living radical polymers and polymers
    Patent number: 7291690
    Abstract: A process for producing a living radical polymer characterized in that a vinyl monomer is polymerized with use of a living radical polymerization initiator represented by the formula (1) and a compound represented by the formula (2), and the living radical polymer obtained by the process wherein R1 is C1-C8 alkyl, aryl, substituted aryl or an aromatic heterocyclic group, R2 and R3 are each a hydrogen atom or C1-C8 alkyl, and R4 is aryl, substituted aryl, an aromatic heterocyclic group, acyl, oxycarbonyl or cyano (R1Te)2??(2) wherein R1 is the same as above.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: November 6, 2007
    Assignee: Otsuka Chemical Co., Ltd.
    Inventors: Shigeru Yamago, Junichi Yoshida
  • Curable silicone resin composition
    Patent number: 7291691
    Abstract: Provided is a curable silicone resin composition including (A) a siloxane/polycyclic hydrocarbon-based compound containing at least 2 silicon-bonded hydrogen atoms, which is an addition reaction product of (a) a siloxane-based compound with at least 3 silicon-bonded hydrogen atoms, and (b) a polycyclic hydrocarbon with at least 2 addition reactive carbon-carbon double bonds, (B) a siloxane-based compound containing at least 2 silicon-bonded alkenyl groups, and (C) a hydrosilylation reaction catalyst. This composition is useful as a material for optical devices or parts, insulation material for electronic devices or parts, or coating material.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: November 6, 2007
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Eiichi Tabei, Akira Yamamoto
  • Polyarylene oxide and method of producing the same
    Patent number: 7291692
    Abstract: A method of producing a polyarylene oxide comprising a step of oxidative polymerization of a monomer represented by the general formula (1) in an organic solvent in the presence of a transition metal compound, wherein, Ar represents a benzene ring or a naphthalene ring, R1 represents a hydrocarbon group optionally substituted, a hydrocarbonoxy group optionally substituted, or a halogen atom; a represents an integer of 0 to 5, and when a is 2 or more, R1s may be the same or different, adjacent R1s may mutually bond to form a ring; R2 represents a single bond or an arylene group; R3 represents a hydrocarbon group optionally substituted or a trialkylsilyl group.
    Type: Grant
    Filed: September 22, 2004
    Date of Patent: November 6, 2007
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hideyuki Higashimura, Yuji Yoshida, Daisuke Fukushima
  • Bioerodible conducting materials
    Patent number: 7291693
    Abstract: The present invention specifically contemplates a polymer, preferably an electrically conductive polymer, derived from substituted pyrrolyl moieties.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: November 6, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Venkatram Prasad Shastri, Alexander Zelikin, David Lynn, Robert S. Langer, Ivan Martin
  • Method and device for producing crystallizable plastic material
    Patent number: 7291694
    Abstract: A method for manufacturing a crystallizable plastic material is disclosed. The process includes the step of melting an amorphous plastic material, pelletizing the material, crystallizing it and then post condensing the plastic material with the proviso that the plastic material is not subjected to heating after the melting step but prior to the crystallization step and then subjecting the plastic material to sieving after the crystallization step.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: November 6, 2007
    Assignees: Buehler AG, Rieter Automatik GmbH
    Inventors: Camille Borer, Martin Mueller, Frank Gloeckner
  • Stable wet strength resin
    Patent number: 7291695
    Abstract: A method of stabilizing an aqueous solution of polyaminoamide-epichlorohydrin resin comprising adjusting the pH of the solution to less than about 3 with strong acid and then adding to the solution a weak acid in a mole ratio of total protons available from the weak acid to total protons available from the strong acid of about 0.05 to about 2.
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: November 6, 2007
    Assignee: Nalco Company
    Inventors: Mingli Wei, Vladimir A. Grigoriev, Gary S. Furman, Jr.
  • Composition and associated method
    Patent number: 7291696
    Abstract: Provided is a fluorine substituted oligomeric or polymeric ester including the reaction product of a fluorine substituted acrylate or a fluorine substituted methacrylate; an unsaturated anhydride; and an alkyl acrylate or an alkyl methacrylate. Also provided is a method of making the composition.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: November 6, 2007
    Assignee: General Electric Company
    Inventors: Hieu Minh Duong, Daniel Steiger
  • Resinates from monomer
    Patent number: 7291697
    Abstract: Reduced-rosin compositions of printing inks and the resinate binders therein, and the processes of preparation thereof, are described. In said compositions, a portion of the rosin normally used in the art is replaced by Monomer, and is further reacted with ?,?-unsaturated carboxylic compound, alkaline metal salt, and solvent to produce the resinate binder product. Said resinate binder may then be formulated with a colorant to produce an ink, preferably for use in publication gravure.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: November 6, 2007
    Assignee: Arizona Chemical Company
    Inventor: Thomas A Fontana
  • Synthetic substrate for high specificity enzymatic assays
    Patent number: 7291698
    Abstract: Novel synthetic enzyme substrates, enhanced to have improved enzymatic specificity, are disclosed. These synthetic enzyme substrates consist of a substrate peptide that has had its specificity further improved by additional synthetic moieties, selected by combinatorial chemistry techniques, that act to sterically block non-target enzymes. These “steric restrictor” moieties may be labeled to produce a detectable signal upon enzymatic reaction. These novel substrates are particularly useful for improved enzyme substrate microarrays. Specific applications for improved protease substrate microarrays are discussed.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: November 6, 2007
    Inventor: Stephen Eliot Zweig
  • Product and methods for diagnosis and therapy for cardiac and skeletal muscle disorders
    Patent number: 7291699
    Abstract: Disclosed are products and methods to promote myoblast activation and cardiac and skeletal muscle growth or regeneration, and to treat heart and skeletal muscle diseases, based on the identification of cellular processes affected by prelamin A processing.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: November 6, 2007
    Assignee: The Regents of the University of Colorado
    Inventor: Gary Brodsky
  • PRO4985 polypeptide
    Patent number: 7291700
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO1777 polypeptides
    Patent number: 7291701
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO4326 polypeptides
    Patent number: 7291702
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO1508 polypeptides
    Patent number: 7291703
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, Colin K. Watanabe, William I. Wood
  • PRO1758 polypeptides
    Patent number: 7291704
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Jian Chen, Luc Desnoyers, Audrey Goddard, Paul J. Godowski, Austin L. Gurney, James Pan, Victoria Smith, Colin K. Watanabe, William I. Wood, Zemin Zhang
  • PRO19645 polypeptides
    Patent number: 7291705
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Austin L. Gurney, William I. Wood, Paul J. Godowski, Colin K. Watanabe, Zemin Zhang, Victoria Smith
  • PRO4352 polypeptides
    Patent number: 7291706
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO1337 polypeptides
    Patent number: 7291707
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO1785 polypeptides
    Patent number: 7291708
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • LSR receptor, its activity, its cloning, and its applications to the diagnosis, prevention and/or treatment of obesity and related risks or complications
    Patent number: 7291709
    Abstract: The present invention relates to a new complex receptor polypeptide LSR (Lipolysis Stimulated Receptor), characterized by its functional activities, the cloning of the cDNAs complementary to the messenger RNAs encoding each of the subunits of the multimeric complex, vectors and transformed cells, methods of diagnosis and of selection of compounds which can be used as medicament for the prevention and/or treatment of pathologies and/or of pathogeneses such as obesity and anorexia, hyperlipidemias, atherosclerosis, diabetes, hypertension, and more generally the various pathologies associated with abnormalities in the metabolism of cytokines.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: November 6, 2007
    Assignees: Serono Genetics Institute S.A., Institut National de la Sante de la Recherche Medicale (INSERM)
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin
  • Detection of spectrin and spectrin proteolytic cleavage products in assessing nerve cell damage
    Patent number: 7291710
    Abstract: Methods for detecting a cell damage relate to the discovery that proteases are selectively activated in subjects suffering from nervous system damage compared to samples from healthy subjects. Breakdown products reflecting activation of proteases that degrade spectrin are produced. A cell injury is detected by providing a biological sample derived from the subject; detecting in the sample the presence of these breakdown products generated by multiple proteases, and correlating the presence of these breakdown products with the presence or type of cell damage.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: November 6, 2007
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Ronald L. Hayes, Kevin K. W. Wang, Brian R. Pike
  • Fluorescent proteins from aquatic species
    Patent number: 7291711
    Abstract: Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from Montastraea cavernosa. Two mutant forms were generated from each wild-type protein. Each of the mutated forms has a higher fluorescence intensity than the respective wild-type form. The mutant forms of the fluorescent proteins allow for more sensitive detection of the fluorescence emitted by the proteins. Additionally, one of the mutant proteins is more resistant to photobleaching than its wild-type protein. The invention also encompasses isolated nucleic acids encoding the mutant forms of the wild-type RFP and GFP.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: November 6, 2007
    Assignee: University of Miami
    Inventors: Patrick D. L. Gibbs, Robert W. Carter, Michael C. Schmale
  • Interleukin-8 homologous polypeptides and therapeutic uses thereof
    Patent number: 7291712
    Abstract: The present invention is directed to novel polypeptides having structural homology to IL-8 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treatment and diagnosis of inflammatory diseases.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Dan L. Eaton, Dorothy French, J. Christopher Grimaldi, Kenneth J. Hillan, Maria Teresa Pisabaro, Kerstin N. Schmidt, Victoria Smith, Daniel Tumas, Richard Vandlen, Colin K. Watanabe, P. Mickey Williams, William I. Wood
  • Branched polyalkylene glycols
    Patent number: 7291713
    Abstract: The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group convertible into the group having reactivity are bound; and a physiologically active polypeptide modified with the branched polyalkylene glycol.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: November 6, 2007
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Motoo Yamasaki, Toshiyuki Suzawa, Tatsuya Murakami, Noriko Sakurai, Kinya Yamashita, Mayumi Mukai, Takashi Kuwabara
  • Glycoprotein VI and uses thereof
    Patent number: 7291714
    Abstract: The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: November 6, 2007
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Samantha J. Busfield, Jean-Luc Villeval
  • Antibodies to the PRO4329 polypeptide
    Patent number: 7291715
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: May 3, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO4400 antibodies
    Patent number: 7291716
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, William I. Wood
  • PRO3446 antibodies
    Patent number: 7291717
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: November 6, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Victoria Smith, Colin K. Watanabe, William I. Wood