Patents Issued in November 13, 2007
  • Lipid analogs for inhibiting HIV-1 activity
    Patent number: 7294620
    Abstract: The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: November 13, 2007
    Assignees: Wake Forest University, University of North Carolina at Chapel Hill
    Inventors: Louis S. Kucera, Susan L. Morris-Natschke, Khalid S. Ishaq
  • Lipid analogs for combating tumors
    Patent number: 7294621
    Abstract: The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the activity of the viral infection.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: November 13, 2007
    Assignees: Wake Forest University, University of North Carolina at Chapel Hill
    Inventors: Louis S. Kucera, Susan L. Morris-Natschke, Khalid S. Ishaq
  • Lactams and uses thereof
    Patent number: 7294622
    Abstract: Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid ? protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit ? secretase and thereby inhibit the production of amyloid ? protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: November 13, 2007
    Assignee: Astrazeneca AB
    Inventors: Christopher Becker, Bruce Dembofsky, Robert Jacobs, James Kang, Cyrus Ohnmacht, James Rosamond, Ashokkumar Bhikkappa Shenvi, Thomas Simpson, James Woods
  • Benzyl morpholine derivatives
    Patent number: 7294623
    Abstract: A compound of formula (I) (I) wherein R is H; Ar is an aromatic group selected from phenyl; X is a phenyl group; R? is H or C1-C4 alkyl; each R1 is independently H or C1-C4 alkyl; and pharmaceutically acceptable salts thereof
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: November 13, 2007
    Assignee: Eli Lilly and Company
    Inventors: Barry Peter Clark, Peter Thaddeus Gallagher, Helen Louise Haughton
  • Barbituric acid derivatives as inhibitors of TNF-? converting enzyme (TACE) and/or matrix metalloproteinases
    Patent number: 7294624
    Abstract: The present application describes novel barbituric acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, L, R1, R2, R3, R4, R5, n, W, U, X, Y, Z, Ua, Xa, Ya, and Za are defined in the present specification, which are useful as TNF-? converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitors.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: November 13, 2007
    Assignee: Bristol Myers Squibb Company
    Inventors: Jingwu Duan, Bin Jiang, Lihua Chen, Zhonghui Lu, Joseph Barbosa, William J. Pitts
  • Pyrazole compounds
    Patent number: 7294625
    Abstract: The present invention relates to pyrazole compounds represented by the formula (I): wherein R1 represents phenyl which may be substituted, R2 represents H, halogen, alkyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl or substituted amino, Q represents CH or N, R3 represents H, alkyl or amino, R4 represents the formula (II) to (V): wherein R7 represents H or alkyl, R8 represents H, alkyl or substituted amino, R9 represents H or alkyl, R12 represents H, alkyl, halogeno alkyl or substituted amino, or pharmaceutically acceptable salts thereof, and a medical composition containing the same as effective ingredient.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: November 13, 2007
    Assignee: Ube Industries, Ltd.
    Inventors: Masahiko Hagihara, Nobuhiko Shibakawa, Masamichi Nishihara, Toshiyuki Shirai, Motohisa Shimizu, Tohru Hasegawa, Yasunori Tokunaga, Naoto Suzuki, Yukinori Wada
  • Piperazines
    Patent number: 7294626
    Abstract: The present invention relates, inter alia, to novel piperazines of the following formula: to the use of these compounds in the preparation of pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, and to methods of treatment employing these compounds or compositions. The compounds show a high and selective binding affinity for the histamine H3 receptor, indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity. As a result, the compounds are useful for the treatment of diseases or disorders related to the histamine H3 receptor.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: November 13, 2007
    Assignee: Novo Nordisk A/S
    Inventor: Rolf Hohlweg
  • Chemical compounds
    Patent number: 7294627
    Abstract: Compounds of formula (I) in which R1, R2, R3 and R4, have the meanings given in the specification are Factor Xa inhibitors useful in the treatment of thrombotic disorders.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: November 13, 2007
    Assignee: Eli Lilly and Company
    Inventors: Steven Douglas Hiscock, Stuart Donald Jones, Daniel Jon Sall, Stephen Clinton Young, Michael Robert Wiley
  • Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
    Patent number: 7294628
    Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4) alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents the aromatic group 1,3-thiazol-2-yl of formula: Preparation process and therapeutic application.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: November 13, 2007
    Assignee: Sanofi-Aventis
    Inventors: Françoise Bono, Michaël Bosch, Victor Dos Santos, Jean-Marc Herbert, Dino Nisato, Bernard Tonnerre, Jean Wagnon
  • Quinazoline derivatives
    Patent number: 7294629
    Abstract: A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a superior tyrosine-specific protein kinase inhibitory activity and is useful as a pharmaceutical agent, particularly as an agent for the prophylaxis or treatment of various cancers, psoriasis or diseases caused by arteriosclerosis, and the like.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: November 13, 2007
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Yasunori Kitano, Eiji Kawahara, Tsuyoshi Suzuki, Daisuke Abe, Masahiro Nakajou, Naoko Ueda
  • Piperazinyl piperidine tachykinin antagonists
    Patent number: 7294630
    Abstract: The present invention provides compounds of formula (I): wherein each R independently represents a halogen atom or a C1-4 alkyl group; R1 represents a C1-4 alkyl group; R2 represents hydrogen or a C1-4 alkyl group; R3 represents hydrogen or C1-4 alkyl group; R4 represents a trifluoromethyl group; R5 represents hydrogen, a C1-4 alkyl group or C(O)R6; R6 represents C1-4 alkyl, C3-7 cycloalkyl, NH(C1-4 alkyl) or N(C1-4alkyl)2; m is zero or an integer from 1 to 3; n is an integer from 1 to 3; or a pharmaceutically acceptable salt or solvate thereof; compositions containing the same, processes for their preparation and methods for their use in the treatment of conditions mediated by tachykinins.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: November 13, 2007
    Assignee: SmithKline Beecham Corporation
    Inventor: Giuseppe Alvaro
  • Substituted 8?-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-]pyrimidin-6-one derivatives
    Patent number: 7294631
    Abstract: The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3?, such as Alzheimer disease.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: November 13, 2007
    Assignees: Sanofi-Aventis, Mitsubishi Pharma Corporation
    Inventors: Nathalie Chereze, Alistair Lochead, Mourad Saady, Franck Slowinski, Philippe Yaiche
  • Substituted 8?-pyridinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a]pyrimidin-6-one and 8?-pyrimidinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a]pyrimidin-6-one derivatives
    Patent number: 7294632
    Abstract: The invention relates to a dihydrospiro-[cycloalkyl]-pyrimidone derivative represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, m, n, p and q are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3?, such as Alzheimer disease.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: November 13, 2007
    Assignees: Sanofi-Aventis, Mitsubishi Pharma Corporation
    Inventors: Pascal George, Alistair Lochead, Mourad Saady, Franck Slowinski, Philippe Yaiche
  • Oxazolo-and furopyrimidines and their use in medicaments against tumors
    Patent number: 7294633
    Abstract: The invention relates to pharmaceutically acceptable compounds of formula I, wherein the radicals have the significances given in the description.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: November 13, 2007
    Assignee: Novartis AG
    Inventors: Guido Bold, Paul W Manley, Andreas Martin-Kohler, Urs Séquin
  • Methods and compositions utilizing quinazolinones
    Patent number: 7294634
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: November 13, 2007
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Substituted isoquinolinones
    Patent number: 7294635
    Abstract: Isoquinolinone compounds are provided that are useful for the inhibition of ADP-platelet aggregation, particularly in the treatment of thrombosis and thrombosis related conditions or disorders.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: November 13, 2007
    Assignee: Portola Pharmaceuticals, Inc.
    Inventors: Robert M. Scarborough, Kim A. Kane-MaGuire, Charles K. Marlowe, Mark S. Smyth, Xiaoming Zhang
  • Chemical compounds
    Patent number: 7294636
    Abstract: Compounds of formula (I): compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating CCR5 receptor activity in a warm blooded animal)
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: November 13, 2007
    Assignee: AstraZeneca AB
    Inventors: John Cumming, Alan Faull
  • Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
    Patent number: 7294637
    Abstract: One aspect of the present invention relates to a method of treating of drug addiction or drug dependence in a mammal, comprising the step of administering to a mammal in need thereof a therapuetically effective amount of a heterocyclic compound, e.g., a 3-substituted piperidine. In a preferred embodiment, the method of the present invention treats cocaine addiction or methamphetamine addiction.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: November 13, 2007
    Assignee: Sepracor, Inc.
    Inventors: Brian M. Aquila, Thomas D. Bannister, Gregory D. Cuny, James R. Hauske, Joanne M. Holland, Paul E. Persons, Heike S. Radeke, Fengjiang Wang, Liming Shao
  • Treatment of ADHD
    Patent number: 7294638
    Abstract: The use of 3-[1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1H-indole, any of its enantiomers and pharmaceutically acceptable salts thereof for the preparation of a pharmaceutical composition for the treatment of attention deficit hyperactivity disorder.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: November 13, 2007
    Assignee: H. Lundbeck A/S
    Inventors: Klaus Peter Hertel, Jorn Arnt
  • Biaromatic ligand activators of PPAR? receptors
    Patent number: 7294639
    Abstract: Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR? receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: November 13, 2007
    Assignee: Galderma Research & Development
    Inventors: Jean-Michel Bernardon, Laurence Clary, Eric Terranova
  • Mitotic kinesin inhibitors
    Patent number: 7294640
    Abstract: The present invention relates to substituted thiazole derivatives that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin and MCAK activity, and for inhibiting KSP kinesin and MCAK. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: November 13, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Paul J. Coleman, Robert M. Garbaccio, Lou Anne Neilson
  • Heterocyclic compound for stimulating or inducing the growth of the hair or eyelashes and/or slowing down their loss, composition comprising it and its uses
    Patent number: 7294641
    Abstract: Heterocyclic compounds useful for stimulating/inducing the growth of keratinous fibers, notably human hair/eyelashes, and/or slowing the loss of same, have the following structural formula (I) or salt thereof: in which Hy is a heterocycle of 4 to 7 atoms, optionally comprising carbonyl/thiocarbonyl functional groups, and G is O, S or NH.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: November 13, 2007
    Assignee: L'Oreal
    Inventors: Christophe Boulle, Roger Rozot, Maria Dalko
  • 1,3-Diamino-2-hydroxypropane pro-drug derivatives
    Patent number: 7294642
    Abstract: The present invention relates to compounds of formula (AA) (I) and (X): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: November 13, 2007
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Yvette M. Fobian, John N. Freskos, Barbara Jagodzinska
  • UK-1 analogues: methods of preparation and use
    Patent number: 7294643
    Abstract: The present invention includes a number of structural analogues of UK-1. A comparision of the anticancer activity of the UK-1 analogues with their ability to inhibit the growth of methicillin-sensitive and methicillin-resistant Staphylococcus aureus demonstrates that a structurally simplified analogue of UK-1 retains the natural product's selective activity against cancer cells. Structurally conservative changes to UK-1 that diminish Mg2+-binding ability may result in a dramatic decrease in cancer cell cytotoxicity. The results may establish a minimum structural pharmacophore as well as a functional role for Mg2+-binding in the selective cytotoxicity of UK-1.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: November 13, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventor: Sean M. Kerwin
  • CB 1 receptor inverse agonists
    Patent number: 7294644
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, m and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: November 13, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Mayweg, Hans Peter Marty, Werner Mueller, Robert Narquizian, Werner Neidhart, Philippe Pflieger, Stephan Roever
  • Derivatives of N?-(1,5-diphenyl-1H-pyrazol-3-yl) sulfonamide with CB1 receptor affinity
    Patent number: 7294645
    Abstract: The invention relates to compounds of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 are as defined herein. The invention also relates to the preparation method thereof and to the use of same in therapeutics.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: November 13, 2007
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Serge Martinez, Murielle Rinaldi-Carmona, Christian Congy
  • Maxi-k channel blockers, methods of use and process for making the same
    Patent number: 7294646
    Abstract: This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of a mammalian species, particularly humans.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: November 13, 2007
    Assignee: Merck & Co. Inc.
    Inventors: Maria L. Garcia, Michael A. Goetz, Gregory J. Kaczorowski, Owen B. McManus, Richard L. Monaghan, William R. Strohl, Jan S. Tkacz
  • Kappa agonist compounds and pharmaceutical formulations thereof
    Patent number: 7294647
    Abstract: Compounds having kappa opioid agonist activity, compositions containing them and 5 method of using them as analgesics and pruritic agents are provided. The compounds of formulae I, II, III and IV have the structure: wherein X, X4, X5, X7, X9; R1, R2, R3, R4; and Y, Z and n are as described in the specification.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: November 13, 2007
    Assignee: Adolor Corporation
    Inventors: Lawrence I. Kruse, An-Chih Chang, Diane L. DeHaven-Hudkins, John J. Farrar, Forrest Gaul, Virendra Kumar, Michael Anthony Marella, Alan L. Maycock, Wei Yuan Zhang
  • Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
    Patent number: 7294648
    Abstract: Anthranylic compounds having anti-CCK activity of general formula (I) in which, n is a whole number lying between 0 and 7; R1 is chosen independently from the groups (II), in which X1 is chosen independently from, S, O, NR2 and X2 is a group chosen from: H, C1-C4 alkyl, F, Cl, CF3, OCH3, OC2H5, CN; R2 is chosen from H or CH3; R3 is chosen from H, CH3, F, Cl, CF3, OCH3; R4 is chosen from the groups: H, —S—(CH2)m-R5, —SO2—(CH2)m-R5 (n different from 0), a branched alkyl group, a cyclo alkyl, a cyclo alkenyl, the group 1 or 2 adamantile, a phenyl group optionally substituted; R5 is chosen from the groups: H, linear or branched alkyl, cyclo alkyl, the group 1 or 2 adamantile, a suitably substituted phenyl group
    Type: Grant
    Filed: July 23, 2003
    Date of Patent: November 13, 2007
    Assignee: Rottapharm S.p.A.
    Inventors: Francesco Makovec, Antonio Varnavas, Lucia Lassiani, Lucio Claudio Rovati
  • Methamphetamine derivatives and conjugates for immunoassay
    Patent number: 7294649
    Abstract: Compounds of methamphetamine derivatives having a meta-substituted alkyl linker on the benzene ring and a protective group on the nitrogen of the methamphetamine hapten. Such compounds have the structure wherein R1 is an alkyl linker comprising 2-15 carbon atoms and 0-6 heteroatoms, R2 is a leaving group, and R3 is a protecting group.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: November 13, 2007
    Assignee: Roche Diagnostics Operatins, Inc.
    Inventors: Raymond A. Hui, Stephen S. Vitone
  • Benzothiophen and thiochrone containing phenethanolamine derivatives for the treatment of respiratory disorders
    Patent number: 7294650
    Abstract: Compounds of formula (I): and salts, solvates, and physiologically functional derivatives thereof, useful for the prophylaxis or treatment of a clinical condition for which a selective ?2-adrenoreceptor agonist is indicated, for example asthma or chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: November 13, 2007
    Assignee: Glaxo Group Limited
    Inventor: Keith Biggadike
  • Inhibition of exoprotein production using isoprenoid compositions
    Patent number: 7294651
    Abstract: Methods and compositions for inhibiting the production of exotoxins are disclosed. The compositions include an effective amount of an isoprenoid inhibitory compound to substantially inhibit the production of exotoxins by Gram positive bacteria.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: November 13, 2007
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Rae Ellen Syverson, Richard A. Proctor
  • Autoimmune conditions and NADPH oxidase defects
    Patent number: 7294652
    Abstract: The invention relates to methods and materials involved in diagnosing and treating autoimmune conditions. In particular, the invention relates to methods and materials involved in diagnosing arthritis conditions that are accompanied by an NADPH oxidase deficiency, methods and materials involved in treating, preventing, or delaying the onset of arthritis conditions that are accompanied by an NADPH oxidase deficiency, and methods and materials involved in identifying agonists and antagonists of NADPH oxidase activity.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: November 13, 2007
    Assignee: Arexis AB
    Inventors: Rikard Holmdahl, Peter Olofsson
  • Silicone antifoaming agent
    Patent number: 7294653
    Abstract: Silicone antifoaming agent of the present invention demonstrates excellent antifoaming effect with regard to aqueous foaming systems, and is especially suitable for use in conjunction with inks where it significantly suppresses development of cissing during use of ink. The silicone antifoaming agent is characterized by comprising a polyoxyalkylene-modified silicone that has polyoxyalkylene groups expressed by general formula (1) and (2) given below and contains 10 to 200 diorganosiloxane units in one molecule, said polyoxyalkylene-modified silicone satisfying the following conditions: 3?E?90 and 0.01?E/(E+P)?0.45, wherein P is the total number of oxypropylene units (—C3H6O—) and E is the total number of oxyethylene units (—C2H4O—) contained in one molecule.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: November 13, 2007
    Assignee: Dow Corning Toray Company, Ltd.
    Inventor: Jianren Zeng
  • Method of making thermally regenerable salt sorbent resins
    Patent number: 7294654
    Abstract: A heterogenous hybrid thermally regenerable salt sorbent resin is formed from a hybrid precursor resin. The hybrid precursor resin is formed by intimately mixing a dry, solid crosslinked macroporous copolymer with a solution containing a polyunsaturated monomer, a monoethylenically unsaturated monomer containing a haloalkyl group and a polymerization initiator, followed by heating to cause polymerization. The hybrid precursor resin is then treated with a weak base, then subjected to hydrolysis conditions to form, respectively, weak base groups and weak acid groups to produce the hybrid thermally regenerable salt sorbent resin.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: November 13, 2007
    Assignee: Novation Environmental Technologies, Inc.
    Inventors: Roger E. Johnson, Gerald Colombo
  • Coating composition for thermoplastic resin particles for forming foam containers
    Patent number: 7294655
    Abstract: Expandable or pre-expanded thermoplastic particles, e.g. polystyrene particles, used to form foam containers e.g. cups, bowls, are coated with a coating composition comprising a liquid part consisting of a) liquid polyethylene glycol with an average molecular weight of 200 to 800; and a solid part comprising components selected from the group consisting of b) polyolefin wax, e.g. polyethylene wax, c) a metal salt of higher fatty acids, e.g. zinc stearate or calcium stearate; d) polyethylene glycol with an average molecular weight of 900 to 10,000; and e) a fatty bisamide or fatty amide, e.g. ethylene bis-stearamide; and combinations of b) through e). The coating composition prevents or resists leakage of liquids and foods with oil and/or fatty components and improves the rim strength and ATF properties of foam containers.
    Type: Grant
    Filed: January 31, 2004
    Date of Patent: November 13, 2007
    Assignee: Nova Chemicals Inc.
    Inventors: Jiansheng Tang, David Allen Cowan, Dennis H. Piispanen, Michael T. Williams
  • UV curable coating composition
    Patent number: 7294656
    Abstract: The present invention is directed to a non-aqueous composition curable by UV radiation broadly comprising a mixture of two UV curable urethane acrylates. The invention is also directed to a coating process using such composition. One of the urethane acrylates is the reaction product of an isocyanate and a specific OH functional lactone ester (meth)acrylate. The other urethane acrylate is the reaction product of an isocyanate and a specific hydroxy functional (meth)acrylate.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: November 13, 2007
    Assignee: Bayer MaterialScience LLC
    Inventors: Hermann Bach, Charles A. Gambino, Michael J. Dvorchak, Michael K. Jeffries, Richard R. Roesler, Ramesh Subramanian
  • Curable acrylate compositions, methods of making the compositions and articles made therefrom
    Patent number: 7294657
    Abstract: A composition comprising a phenylthioethylacrylate, a multifunctional (meth)acrylate, a curing agent, wherein the phenylthioethylacrylate comprises less than about 400 parts per million tin and less than about 2 percent by weight of the corresponding phenylthioethanol. The composition may further comprise at least one unsaturated acid.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: November 13, 2007
    Assignee: General Electric Company
    Inventors: Daniel Robert Olson, Dennis Joseph Coyle, Christian Andrew Huntley, Bret Ja Chisholm, Paul Michael Smigelski, Jr., Alvin Un-Teh Chen
  • Radiation-cured, laminated flexible packaging material and radiation-curable, adhesive composition
    Patent number: 7294658
    Abstract: Provided are laminated flexible packaging materials (20) suitable for containing a pharmaceutical, food or beverage grade product. The laminated flexible packaging material includes a layer of flexible packaging material (26) bound to at least one other layer of flexible packaging material (22) by a radiation-cured laminating adhesive composition (24) formulated from a radiation-curable laminating adhesive containing at least 50% of one or more radiation-curable, carboxylic acid functional monomers and 0.1 to 20% of an organic titanate compound. Also provided is a radiation-curable laminating adhesive containing at least 50% of one or more radiation-curable, carboxylic acid functional monomers and 0.1 to 20% of an organic titanate compound.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: November 13, 2007
    Assignee: Ashland Licensing and Intellectual Property LLC
    Inventors: Kevin D. Rea, Stephen C. Lapin, Paul Eugene Snowwhite, Jr.
  • Aqueous ink composition
    Patent number: 7294659
    Abstract: An aqueous ink composition comprising: a pigment, having a particle diameter as determined by the light scattering method of no less than 20 nm and no more than 200 nm; and a water dispersible polymer, having a styrene-equivalent number average molecular weight of as determined by gel permeation chromatography no less than 5000 and no more than 200000, having a surface tension of no less than 20 mN/m and no more than 40 mN/m, and wherein the abovementioned pigment is a polymer-coated pigment that is coated with the abovementioned water dispersible polymer, is provided. The water-dispersible polymer may be a copolymer of monomers, mainly comprising acrylic acid and/or methacrylic acid and an acrylate and/or methacrylate. With this ink composition, the printing quality can be improved.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: November 13, 2007
    Assignee: Seiko Epson Corporation
    Inventor: Masahiro Yatake
  • Epoxy resin composition
    Patent number: 7294660
    Abstract: An epoxy resin composition which comprises 100 parts by weight of an epoxy resin and 1 to 800 parts by weight of an aluminum borate whisker having an average fiber diameter of 0.25 ?m or less. The epoxy resin composition contains a large amount of the aluminum borate whisker being dispersed uniformly therein, is excellent in mechanical strength, and is suppressed with respect to the anisotropy of a mechanical property due to the direction of application.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: November 13, 2007
    Assignee: Asahi Denka Co., Ltd.
    Inventors: Seiichi Saito, Yoshihiro Fukuda, Takahiro Mori, Yoshinori Takahata
  • Flame resistant aromatic polyamide resin composition and articles therefrom
    Patent number: 7294661
    Abstract: The present invention relates to a flame resistant polyamide resin compositions for moulded articles and articles formed therefrom, comprising aromatic polyamide with phosphinate and/or diphosphinate flame retardant and, optionally, glass fibers. Further provided are articles for use in a variety of applications including electrical and electronic parts requiring electrical insulation.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: November 13, 2007
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Marvin M. Martens, Yuji Saga
  • Resin compositions and uses thereof
    Patent number: 7294662
    Abstract: The invention pertains to a resin composition comprising a polymer and a solvent, characterized in that the polymer is obtained by polymerizing the following monomers: (a) an acrylate monomer; (b) a tertiary carboxylic ester; and (c) a monomer selected from the group consisting of a fluoro acrylate monomer, a siloxane monomer, and a mixture thereof. The resin composition of the invention can be formulated into a coating for a substrate to impart stain resistance to the coated surface.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: November 13, 2007
    Assignee: Eternal Chemical Co., Ltd.
    Inventors: Mao-Jung Yeh, Chun-Hsiung Chang
  • Compatibility improvement in aromatic polyesters with mineral fillers
    Patent number: 7294663
    Abstract: Liquid crystalline polymers (LCP) with relatively high melting points are prepared by a process which includes solid state polymerization of a (pre)polymer, which contains alkali metal cations, to raise the LCP molecular weight. The presence of the alkali metal cations in the (pre)polymer usually results in a final polymer with less color and/or a higher melting point. The LCPs are useful as molding resins and for films.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: November 13, 2007
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Edmund A. Flexman, Mark Weinberg
  • Elastomeric blend for air barriers comprising grafted resin components
    Patent number: 7294664
    Abstract: A composition suitable for an air barrier such as an automotive tire innertube, innerliner, and aircraft tire innertube or innerliner, curing bladders, and other pneumatic devices is disclosed. The composition comprises an elastomer, a processing oil, and a grafted resin component.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: November 13, 2007
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Glenn Edward Jones, Mun Fu Tse, Hsien-Chang Wang, Kenneth Lewtas, William Moa-Tseng Chien, Walter Harvey Waddell
  • Moisture curable compositions with enhanced adhesion to polyolefins
    Patent number: 7294665
    Abstract: Moisture curable compositions that include alkoxysilyl capped polymer compounds and alkylsilyl capped plasticizers adhesively cure to polyolefin substrates, including polyethylene and polyolefin substrates. The compositions are curable at room temperature or at temperatures greater than room temperature. The compositions further include an adhesion promoter, a filler or a moisture curing catalyst.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: November 13, 2007
    Assignee: Henkel Corporation
    Inventor: Thomas Fay-Oy Lim
  • Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups
    Patent number: 7294666
    Abstract: This invention relates to a tire having at least one component of a silica reinforced rubber composition comprised of an emulsion polymerization derived terpolymer rubber which contain pendant hydroxyl groups, particularly derived from diene hydrocarbon and vinyl aromatic compound monomers, particularly a hydroxyalkyl methacrylate. Preferably the hydroxyalkyl methacrylate is a hydroxypropyl methacrylate (HPMA). Preferably at least one additional elastomer is blended with the terpolymer rubber. The rubber composition is prepared by blending a coupling agent therewith subsequent to the addition said silica reinforcement. Said tire component may be, for example, a tire tread.
    Type: Grant
    Filed: March 4, 2002
    Date of Patent: November 13, 2007
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Georges Marcel Victor Thielen
  • Coated abrasive articles containing graphite
    Patent number: 7294667
    Abstract: Coated abrasive articles comprise a composition comprising binder and at least about 25% by weight graphite particles, based on the total solids content of the composition.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: November 13, 2007
    Assignee: 3M Innovative Properties Company
    Inventor: Michael L. Teetzel
  • Aqueous dispersions of polytetrafluoroethylene having a low amount of fluorinated surfactant
    Patent number: 7294668
    Abstract: An aqueous non-melt processible polytetrafluoroethylene dispersion having non-melt processible polytetrafluoroethylene particles in an amount of 30 to 70% by weight and an amount of non-ionic surfactant between 2 and 15% by weight based on the weight of polytetrafluoroethylene solids. The dispersion is free of fluorinated surfactant or contains fluorinated surfactant in amounts of not more than 200 ppm based on the amount of polytetrafluoroethylene solids. At least part of the non-melt processible polytetrafluoroethylene particles comprise an effective amount of ionic end groups in the polytetrafluoroethylene polymer chains.
    Type: Grant
    Filed: February 7, 2006
    Date of Patent: November 13, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Tilman Zipplies, Klaus Hintzer, Michael C. Dadaias, Gernot Loehr
  • Sealant having improved dynamic durability
    Patent number: 7294669
    Abstract: An object of the present invention is to provide a low-modulus, high elongation sealant having improved dynamic durability, desirable mechanical properties, and good workability. The present invention provides a sealant containing an oxyalkylene polymer (A) having a number-average molecular weight of 20,000 to 50,000 and 0.8 or more of reactive silicon groups per molecule on average; 10 parts by weight or more of a plasticizer (B) per 100 parts by weight of the polymer (A); a filler (C); and a curing catalyst (D). This sealant has an improved durability and can achieve the above-described object.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: November 13, 2007
    Assignee: Kaneka Corporation
    Inventor: Hiroshi Ito