Abstract: A complex medical balloon (12) has at least two sections (14, 16), each of which has a different compliance curve. A compliance curve measures expansion size at various pressures. Accordingly, at a given pressure, one balloon section of a complex balloon will experience greater expansion than another section.

Abstract: An intragastric balloon that is left in an inflated state inside a stomach includes: a balloon main body that is capable of being inflated to a predetermined size; and at least one or more internal passages that are formed in the balloon main body so as to penetrate the balloon main body, and that allow contents of the stomach to be passed.

Abstract: Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies.

Abstract: Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies.

Abstract: Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies.

Abstract: The present invention relates to external devices for dilating nasal passageways and to the manufacture thereof. More specifically, the external nasal dilator of the present invention usually comprises a resilient sheet, an adhesive layer, and an adhesive-protecting sheet. In some embodiments of the external nasal dilator, the resilient sheet defines a groove for reducing the peel force that results from bending the dilator over the bridge of the nose. In addition to the groove or in lieu thereof, some embodiments of the external nasal dilator comprise a nasal passage region having a reduced width to reduce the peel force. Finally, the dilator can comprise a sheet of adhesive tape, which in some embodiments can provide an instant tack surface to facilitate application of the dilator.

Abstract: A vessel filter comprising a first region and a second region wherein the filter is movable between a collapsed position for delivery to the vessel and an expanded position for placement within the vessel. A first region has a filter portion having a converging region to direct particles toward the center of the filter and the second region is flared in the expanded position to have a transverse dimension increasing toward a second end portion opposite the first end portion. The second region includes a vessel engaging portion at the second end portion. The first region includes a plurality of spaced apart elongated struts with adjacent struts being joined.

Abstract: A medical instrument, particularly a surgical instrument with a displaceable push/pull activation tube arranged on the proximal end of a hand manipulator, that also contains an inner tube for retaining a fixed jaw, for activating remote tool parts on the distal end, in which a force-limiting device limits the transmission of force to the remote tool parts from the hand manipulator via an extendable coil spring. The medical instrument optionally features a fiber scope to enable optical viewing to locate the implanted device for removal as well as a saline flush capability. The instrument has jaws that are cylindrical in shape to facilitate grasping an implanted cylindrical device.

Abstract: The present invention provides a flexible actuator, and methods for manufacturing and using a flexible actuator, for transmitting high loads from a user to an end effector. In one exemplary embodiment, the flexible actuator can extend from a handle of a medical device to an end effector located on a distal end of the device. The actuator can include a head formed on a terminal end thereof with at least one planar surface that is approximately coplanar with an outer surface of the flexible actuator. In use, the actuator can be coupled to a medical device having an end effector located on a distal end thereof. Tension applied to the actuator can be effective to actuate the end effector.

Abstract: Apparatus for sealing a puncture communicating with a blood vessel includes a porous carrier formed from lyophilized hydrogel or other material. The plug may include at least first and second hydrogel precursors and a pH adjusting agent carried by the porous carrier in an unreactive state prior to exposure to an aqueous physiological environment. Once exposed to bodily fluids, the carrier expands as the lyophilized material hydrates to enhance and facilitate rapid hemostasis of the puncture. When the plug is placed into the puncture, the natural wetting of the plug by bodily fluids (e.g., blood) causes the first and second precursors to react and cross-link into an adhesive or “sticky” hydrogel that aids in retaining the plug in place within the puncture.

Abstract: Several alternative designs, structures, assemblies, treatment methods and/or methods of manufacturing medical closure devices adapted and/or configured for closing an opening, for example, an incision or a puncture in the tissue of a patient, for example, the dural membrane of a patient. Some embodiments include a medical closure device including an elongated tubular member extending along a longitudinal axis. The tubular member including a distal section and a proximal section, and the distal section is expandable from a first configuration to a second expanded configuration through the application of a compressive force upon the distal section along the longitudinal axis.

Abstract: A helical fastener having a high retentive surface area is provided and has a first end for enhancing penetration into tissue and a second end comprising a coil sectioning a diameter of the fastener for receiving longitudinal and rotational forces. The helical fasteners are attached to body tissue by a fastener applicator having a proximal portion comprising a handle and an actuator and an elongate distal portion for housing a plurality of fasteners. A transferring action of the actuator provides longitudinal and rotational movement of the fasteners out of the distal portion and into body tissue.

Abstract: A surgical thread and a surgical device. The surgical thread includes at least two adjacent elongated elements that are connected to each other and include filament fibers such that a maximum cross-sectional diameter of the thread is substantially greater than the cross-sectional diameter of the thread in the direction perpendicular to the maximum diameter, and the elements are connected by a structure that is arranged to be broken at least at the ends of the elements such that the thread can be divided into single elements. The surgical device includes a needle and a surgical thread attached to the surgical needle.

Abstract: Unique PTFE structures comprising islands of PTFE attached to an underlying expanded polytetrafluoroethylene (ePTFE) structure and to methods of making such structures is disclosed. The ePTFE material may or may not have been exposed to amorphous locking temperatures. These unique structures exhibit islands of PTFE attached to and raised above the expanded PTFE structures.

Abstract: Mastopexy or breast lift surgery involves inserting permanent and reabsorbable threads under the skin that follow a skin marker drawn by the operator. This enables the interested area to be lifted without leaving vertical or inverted T scars on the patient's breast or any other type of scar.

Abstract: A suture attachment device for fastening multiple suture filaments at a wound or surgical site is provided. In one embodiment, the suture attachment device comprises a lock body having a proximal surface and a distal surface and extending along a longitudinal axis. The lock body includes at least two passageways defined between the proximal surface and the distal surface. Each of the passageways are sized and shaped for receiving a suture filament.

Abstract: A device which comprises pacifiers used by animals.

Abstract: Disclosed herein are circuits and methods for a multi-electrode implantable stimulator device incorporating one decoupling capacitor in the current path established via at least one cathode electrode and at least one anode electrode. In one embodiment, the decoupling capacitor may be hard-wired to a dedicated anode on the device. The cathodes are selectively activatable via stimulation switches. In another embodiment, any of the electrodes on the devices can be selectively activatable as an anode or cathode. In this embodiment, the decoupling capacitor is placed into the current path via selectable anode and cathode stimulation switches. Regardless of the implementation, the techniques allow for the benefits of capacitive decoupling without the need to associate decoupling capacitors with every electrode on the multi-electrode device, which saves space in the body of the device.

Abstract: A system for stimulating tissue to relieve pain and repair and/or regenerate tissue comprising a garment that has an electrode, a programmable electrical stimulation device, a time varying electromagnetic field generator, and a source that provides an electrical current. Also provided is a method wherein the electrode provides the user with a stimulating current and the time varying electromagnetic field provides the user with a time varying electromagnetic field either simultaneously, alternating, and/or sequentially.

Abstract: An implantable cardiac device includes a housing (2), pulse generator (7) therein to generate physiologically effective electrical pulses, a shock lead (3), externally of the housing (2), connectable to the pulse generator (7) and implantable into a patient's body to apply physiologically effective electrical pulses to the patient's body, a monitor (8) to automatically detect a lead condition as to whether the shock lead (3) is implanted or not, and control (9), which due to the detected lead condition automatically enables or disables the pulse generator (7).

Abstract: A method and apparatus are provided for controlling interrogation of an implantable device such as a pacemaker, an implantable cardioverter, or a defibrillator utilizing an external device in a home environment. The method controls how frequently a patient can retrieve status information from the implantable device based on a time period elapsed since a last interrogation and a power level of a battery.

Abstract: A multilingual defibrillator is capable of concurrently providing audible prompts for the operation of the defibrillator in multiple languages. The defibrillator includes a memory for storing data files representative of audible prompts in a plurality of languages. A controller is coupled to the memory and configured to select data files of audible prompts in first and second languages and generate first electrical signals and second electrical signals representative of the audible prompts in the first and second languages, respectively. First and second audible sound generators are coupled to the controller to receive respective electrical signals and configured to generate audible output in response to the respective electric al signals.

Abstract: A resuscitation system includes a chest compression device to repeatedly compress the chest of a patient and thereafter cause or allow the chest to expand. The resuscitation system also includes a defibrillator to apply electric impulses to the heart, a measuring device for measuring at least one characteristics of the resuscitation process, and a signal processor for controlling operation of the chest compression device and/or the defibrillator. The defibrillator may be an integrated or external device working in a master/slave relationship with the remaining system.

Abstract: Methods, systems and computer program products for reducing a risk of pulseless electrical activity (PEA) include detecting a first post-defibrillation blood flow of a subject and detecting a second post-defibrillation blood flow of the subject after the first post-defibrillation blood flow. If the first post-defibrillation blood flow of the subject is above a first threshold value and the second post-defibrillation blood flow is below a second threshold value, a plurality of electrical pulses that reduces a risk of PEA.

Abstract: A method and system are disclosed for setting the pacing parameters utilized by an implantable cardiac device in delivering cardiac resynchronization therapy. The system may, in different embodiments, be implemented in programming of the implantable device and an external programmer in communication therewith or in the programming of the implantable device by itself. The selection of the pacing parameters is based at least in part upon measurements of intrinsic cardiac conduction parameters. Among the pacing parameters which may be selected in this way are the atrio-ventricular delay interval used in atrial-tracking and AV sequential pacing modes and the biventricular offset interval.

Abstract: A method and system decomposes a cardiac signal, such as an electrocardiogram (ECG) signal, into components. The components are then usable to assist in the detection of an abnormal heart condition. More particularly, a single lead sensor is used to generate a single lead cardiac signal. The cardiac signal is segmented into a set of cycle segments according to detected heart waveforms. The cycle segments are aligned and used to generate a set of cross-sectional signals. The cross-sectional signals are aligned and presented as inputs to a signal separation process, which separates the cardiac signal into a set of components. The components may be grouped according to predefined criteria. The components or groups may be analyzed or displayed to assist in the detection of an abnormal cardiac signal, which may be indicative of an abnormal heart condition. In one example, the signal separation process is a non-orthogonal transformation method such as independent component analysis (ICA).

Abstract: A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.

Abstract: A cardiac rhythm management (CRM) system detects tachyarrhythmia using cardiac local impedance indicative of cardiac local wall motion. A cardiac local impedance signal indicative of an impedance of a cardiac region is sensed by using a pair of bipolar electrodes placed in that cardiac region. Tachyarrhythmia such as VF is detected by analyzing one or more cardiac local impedance signals sensed in one or more cardiac regions.

Abstract: A monitoring device is provided to monitor a patient. The monitoring device includes at least one lead having an electrode. The lead is positioned proximate a location within the patient's body, and the lead is adapted to sense cardiac electrical activity. The monitoring device also includes a control system coupled to the at least one lead to receive a signal representative of the cardiac electrical activity.

Abstract: A cardiac electro-stimulatory device and method for operating same in which stimulation pulses are distributed among a plurality of electrodes fixed at different sites of the myocardium in order to reduce myocardial hypertrophy brought about by repeated pacing at a single site and/or increase myocardial contractility. In order to spatially and temporally distribute the stimulation, the pulses are delivered through a switchable pulse output configuration during a single cardiac cycle, with each configuration comprising one or more electrodes fixed to different sites in the myocardium.

Abstract: A method and apparatus for predicting acute response to cardiac resynchronization therapy is disclosed. The method can comprise measuring a first interval during an intrinsic systolic cycle and measuring a second interval during a stimulated systolic cycle. The acute response can be predicted by comparing the percent change in duration between the first interval and the second interval against a pre-determined threshold value. The first and second time intervals can be measured using, for example, a surface ECG or, alternatively, an intracardiac electrogram. In one embodiment, the first interval can be the duration of an intrinsic QRS complex measured during a non-stimulated systolic cycle. Similarly, the second interval can be the duration of a stimulated QRS complex measured during a stimulated systolic cycle.

Abstract: A system and method for cardiac rhythm management, which includes an electrode system having at least one electrode and control circuitry coupled to the electrode system from which a first cardiac signal is sensed. The control circuitry includes a pulse circuit to produce electrical pulses at a first value to be delivered to the electrode system in a first cardiac region. At least one cardiac signal is sensed from a second cardiac region, where the cardiac signal includes indications of cardiac depolarizations from the second cardiac region which occurs in direct reaction to the electrical pulses delivered to the first cardiac region. The first value of the electrical pulses are then modified by a pulse adjustment circuit when a cardiac depolarization which occurs in direct reaction to the electrical pulse delivered to the first cardiac region is detected from the second cardiac region.

Abstract: One aspect of this disclosure relates to a system for dynamic battery management in implantable medical devices. An embodiment of the system includes two or more devices for measuring battery capacity for an implantable medical device battery. The embodiment also includes a controller connected to the measuring devices. The controller is adapted to combine the measurements from the measuring devices using a weighted average to determine battery capacity consumed. According to various embodiments, at least one of the measuring devices includes a coulometer. At least one of the measuring devices includes a capacity-by-voltage device, according to an embodiment. The system further includes a display in communication with the controller in various embodiments. The display is adapted to provide a depiction of battery longevity in units of time remaining in the life of the implantable medical device battery, according to various embodiments. Other aspects and embodiments are provided herein.

Abstract: A method and apparatus are provided for controlling interrogation of an implantable device such as a pacemaker, an implantable cardioverter, or a defibrillator utilizing an external device in a home environment. The method controls how frequently a patient can retrieve status information from the implantable device based on a time period elapsed since a last interrogation and a power level of a battery.

Abstract: A defibrillator electrode and enclosure are described in which the electrodes are sealed to the inside of a rigid enclosure. The enclosure is hinged to open and expose the electrodes for deployment. The electrode gel is sealed against moisture loss between the moisture impervious electrode backing and the inner surface of the enclosure. The enclosure may further include an electrical circuit for electrode self-testing, the circuit being broken when the enclosure is opened.

Abstract: Methods and devices for verifying that proper visual stimulation is applied to the visual prostheses are described. In one of the methods, a retinal stimulation system implanted on a subject is simulated externally. An external testing device is also discussed.

Abstract: A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit.

Abstract: An electrode assembly for delivering electrical stimulation to a vestibular system of a user or monitoring a physiological parameter of the user. The apparatus includes a body member comprising an electrode support portion and a curved portion extending from the electrode support portion, and an electrode coupled to the electrode support portion. A method of using such an apparatus is also disclosed. The present invention also provides an electrode assembly that includes a body member, an electrode coupled to the body member, a hydrogel element disposed on at least a portion of the electrode. In one embodiment, the hydrogel element includes a hydrogel material and a insulating material disposed on or in the hydrogel material such that the insulating layer disperses energy transmitted by the electrode through the hydrogel material.

Abstract: A method according to one aspect of the present invention includes receiving patient information, analyzing the patient information to identify a condition for the patient, formatting a report based on the patient information and the patient condition, and transmitting a command. Commands can be used for the authentication, configuration, and control of a medical device, intermediary device or another device operating in conjunction with the present invention, as well as to achieve other purposes. Embodiments of the present invention may be used to monitor any appropriate medical device from essentially any location from which a communications signal can be sent and received. This enables patients to enjoy an active lifestyle by not being tied to medical device monitoring equipment that is difficult or impossible to transport or having to routinely visit health care facilities.

Abstract: A method according to an aspect of the present invention includes receiving data through a wired connection from a medical device, storing the data, transmitting the data to an intermediary device, and formatting a message including the received data for transmission to a medical data server. This method can be practiced automatically to allow a medical device for a patient or other subject to be monitored without requiring the patient to manually enter information. This method allows the data to be stored for any desired length of time, and/or until a particular event occurs.

Abstract: A method according to the present invention includes receiving data through a wired connection from a medical device by a mobile computing device, where the wired connection includes an adapter that communicates with the mobile computing device using a first communication format and the medical device using a second communication format. The method further includes formatting a message including the received data for transmission to a medical data server by the mobile computing device. This method may be practiced automatically, either continuously or at set intervals, or may be initiated by someone utilizing the system (such as the patient or health care provider. The mobile computing device can be a properly-equipped cellular telephone, PDA, or other a small, portable device that is easy for a patient to transport.

Abstract: Systems and methods are described for adjusting the operation of implantable stimulation devices used to provide medical monitoring and treatment. Several hierarchical algorithms are described which operate according to conditionally obtaining a patient response to an alert signal. In one such strategy semi-automatic therapy adjustment occurs by automatically issuing patient alert messages when selected operations are to occur, and using a patient's response to the alert message that is provided within a selected time limit in order to contingently adjust therapy. Methods are also described for resolving conflicts which may occur when time information and sensed data information each indicate different patient states are occurring. Although treatment of neural and cardiac disorders is emphasized, the techniques can be applied to the monitoring and treatment of any medical disorder with an implanted device.

Abstract: An improved structure for an implantable medical device, such as an implantable pulse generator, is disclosed. The improved device includes a charging coil for wirelessly receiving energy via induction from an external charger. The charging coil in the device is located substantially equidistantly from the two planar sides of the device case. Because the coil is substantially equidistant within the thickness of the case of the device, the device's orientation within the patient is irrelevant, at least from the standpoint of the efficiency of charging the device using the external charger. Accordingly, charging is not adversely affected if the device is implanted in the patient with the wrong orientation, or if the device flips within the patient after implantation.

Abstract: The present invention is a power and data transmission system for an implantable device. In particular, it is an inductive system with a passive repeater coil pair to improve efficiency of the device.

Abstract: A device for sensing and communicating nerve cell endings and neural signals, the device comprising: at least one neural bridge device; at least one neural bridge switch, wherein each neural bridge switch is an implanted integrated circuit and is connected to at least one neural bridge device; at least one neural bridge gateway; at least one communication means in communication with at least one neural bridge gateway and at least one neural bridge switch; at least one sensory interface integrated circuit in communication with at least one neural bridge switch; at least one transducer in communication with at least one sensory interface integrated circuit; and at least one attachment means in communication with at least one transducer.

Abstract: Implant apparatus and method for effecting a controlled heating of tissue within the region of dermis of skin. The heater implants are configured with a thermally insulative generally flat support functioning as a thermal barrier. One surface of this thermal barrier carries one or more electrodes within a radiofrequency excitable circuit as well as an associated temperature sensing circuit. The implants are located within heating channels at the interface between skin dermis and the next adjacent subcutaneous tissue layer such that the electrodes are contactable with the lower region of dermis. During therapy a conformal heat sink is positioned against the skin above the implants and a slight tamponade is applied through the heat sink to assure uniform dermis contact with electrode surfaces. An adjuvant may be employed to infiltrate dermis to significantly lower the thermal threshold transition temperature for dermis or dermis component shrinkage.

Abstract: Method, system and apparatus for carrying out a controlled heating of tissue in the region of skin dermis. A quasi-bipolar arrangement of wands or implants carrying multi-segmented active electrodes, temperature sensing and wand location LEDs as combined with a return electrode and heat sink function. Radiofrequency energization of the active electrodes is carried out in a ramping-up and pulsing fashion to provide relatively short therapy intervals. The combined return electrode and heat sink components may incorporate photo-detectors, which perform to insure proper alignment with the LED carrying active electrode sequences. An isotonic saline solution is located intermediate the contact surface of the combined return electrode and heat sink and the surface of skin over implanted active electrodes.

Abstract: Method for effecting a controlled heating of tissue within the region of dermis which employs heater implants which are configured with a thermally insulative generally flat support functioning as a thermal barrier. From the surface of this thermal barrier are supported one or more electrodes within a radiofrequency excitable circuit as well as an associated temperature sensing circuit. A model of R.F. current path flow is developed resulting in a current path index permitting a prediction of current path flow. Improved electrode excitation is developed with an intermittent R.F. excitation of electrodes shortening therapy time and improving skin protection against thermal trauma.

Abstract: A thermal cap that can fit a variety of head sizes is disclosed. The cap can include a shell having a fluid inlet and outlet, a sealing mechanism and removable sizing layers disposed within the shell. Depending upon the size of a patient's head, sizing layers can either be added to or removed from the outer shell to maintain a fluid circulation space between the head and the rigid shell and allow substantially even distribution of a thermal fluid about the scalp of the patient during operation. The shell is preferably rigid and an elastomeric member can seal the periphery of the cap to the patient's head to prevent leakage. Other types and aspects of thermal cap systems are also disclosed.

Abstract: Various types of body heating or cooling devices are described in the present disclosure. Such devices, and associated methods, can utilize two separated thermal transfer fluids to promote heating or cooling of a body part. For example, a cooling cap can include a rigid shell and a flexible seal that form a fluid containment space with a patient's head. The rigid shell can include a fluid circulation apparatus disposed within the fluid containment space, and be coupled to a console pump to form a closed loop circulation system. A volume of fluid can be introduced into the fluid containment space to contact the patient's scalp. The console pump can then circulate a thermal transfer fluid through the fluid circulation apparatus to reduce the temperature of a fluid held within the fluid containment space.