Abstract: The current invention relates to a fluorinated elastomer latex containing an aqueous medium, a fluorinated elastomer dispersed in the aqueous medium in an amount of from 10 to 60 mass % and a fluorinated emulsifier represented by the formula (1): C2F5O(CF2CF2O)mCF2COOA (wherein A is a hydrogen atom, an alkali metal or NH4, and m is an integer of from 1 to 3), which employs no perfluorooctanoate emulsifier and which is excellent in dispersion stability of the fluorinated elastomer.

Abstract: The present invention relates to modified alkoxysilane-functional polyurethanes containing allophanate and/or biuret groups, wherein at least 10 mol % of the allophanate and/or biuret groups are formed from a monoisocyanate of the formula R—NCO, wherein R is an optionally heteroatom-containing alkyl, aralkyl or aryl radical having up to 20 carbon atoms, provided that these radicals do not contain any other reactive groups with the exception of the NCO group that is part of the allophanate structure and any alkoxysilyl groups present.

Abstract: An aqueous multicomponent coating material comprising (I) an aqueous component preparable by mixing at least the following starting products: (A) at least one secondary aqueous dispersion of at least one (meth)acrylate copolymer containing on average per molecule at least one isocyanate-reactive functional group, (B) at least one primary aqueous dispersion of at least one (meth)acrylate copolymer containing no isocyanate-reactive functional group, and (C) at least one pigment and/or one filler; and also (II) a component comprising at least one polyisocyanate as crosslinking agent, and also a process for preparing it, and its use.

Abstract: The present invention relates to an aqueous polymer dispersion comprising a copolymer of anhydride monomer units and vinyl monomer units, which copolymer has been subjected to an imidization reaction. The present invention further relates to a method for the production and use of such a dispersion.

Abstract: Coating compositions for cementitious substrates may be made from a silane-functional multistage latex polymer. The compositions adhere well to cementitious substrates and resist crush damage such as may be caused by stacking coated substrate boards.

Abstract: Electrophoretic particles are constituted by pigment particles provided with a polymer chain connected with a polymerization initiation group at a surface of pigment particle. The resultant electrophoretic particles are excellent particle size uniformity and dispersibility.

Abstract: This invention discloses a process for synthesizing a hairy polymer particle which comprises the steps of (1) polymerizing a vinyl aromatic monomer by emulsion polymerization in an aqueous medium to produce core particles, (2) recovering the core particles from the aqueous medium, (3) dispersing the core particles in an organic solvent, (4) adding an organo-lithium compound to the dried core particles in the organic solvent to produce the hairless core initiator, and (5) utilizing the hairless core initiator to initiate the anionic polymerization of a conjugated diolefin monomer in an organic solvent to produce a solution of the hairy polymer particles. The hairy polymer nanoparticles can then be recovered from the organic solvent. These hairy polymer particles are comprised of (1) a core which is comprised of a polymer of a vinyl aromatic monomer and (2) hairs which are polymer chains of a conjugated diolefin monomer, wherein the hairs are covalently bonded to the core.

Abstract: A method of preparing a thermoplastic vulcanizate, the method comprising dynamically vulcanizing a rubber within a blend with a thermoplastic resin, where the dynamic vulcanization is effected with a cure system that includes a free-radical cure agent and triallyl isocyanurate.

Abstract: The invention relates to a polymer blend suitable for the production of film, said polymer blend comprising at least (1) a multimodal high density polyethylene (HDPE) composition and (2) a low density polyethylene (LDPE) polymer, a linear low density polyethylene (LLDPE) polymer or a mixture of LDPE and LLDPE polymers, said HDPE composition comprising a multimodal HDPE polymer which contains at least a lower molecular weight (LMW) polyethylene component and a higher molecular weight (HMW) polyethylene component.

Abstract: A polyethylene resin suitable for formation into pipes or pipe fittings is disclosed, having an MI5 of from 0.40 to 0.70 g/10 min, and comprising from 47 to 52 wt % of a low molecular weight polyethylene fraction, and from 48 to 53 wt % of a high molecular weight polyethylene fraction, wherein the high molecular weight polyethylene fraction comprises a copolymer of ethylene and 1-hexen or 1-octene.

Abstract: A method for modifying a polymer by mixing and reacting a polymer (A), a compound (B) having a nitroxide radical in the molecule thereof, a radical initiator (C), and a radical polymerizable monomer (D) in a non-solvent system in a mixed to thereby graft a monomer (D) to the polymer (A), whereby a desired functional group is introduced to the polymer, without a causing decrease in the molecular weight, gelation, or formation of a homopolymer.

Abstract: An improved curable formaldehyde-free binding composition is provided. Such curable composition comprises the reaction product of a polyanhydride and a polyol crosslinker and a lower molecular weight anhydride. Initially, the polyanhydride is modified through reaction with a polyol (e.g., a glycol or an alkanolamine) and subsequently is grafted with the lower molecular weight anhydride (e.g., maleic anhydride) to form a water-soluble or water-dispersible curable reaction product. The composition is well suited for binding fibrous materials (e.g., a mat of glass fibers) or for bonding together non-fibrous materials. The binder composition displays an advantageous viscosity so as to facilitate a flowable application with ease combined with an adequately high molecular weight to satisfactorily undergo service as a binder following curing even when harsh environmental conditions (e.g., hot humid air) are encountered for a prolonged period of time.

Abstract: Disclosed is a bearing material of a medical implant comprising a polymer such as UHMWPE and a surface active agent that is not covalently bonded to the polymer. The bearing material has a reduced wear rate. Also disclosed is a method of reducing the wear rate of a polymeric bearing material of a medical implant when it articulates against a hard counterface in the presence of synovial fluid, the method comprising providing a surface active agent in the synovial fluid in close proximity to the bearing surface, the hard counterface, or both.

Abstract: The invention describes a process for preparing pulverulent polyimide-polyimide block copolymers. The result polyimide-polyimide block copolymers and compounds produced using them can be compressed into moldings by the direct forming method or by the hot compression molding method. Polymeric moldings can be produced therefrom by customary mechanical and thermal machining and forming methods.

Abstract: The invention relates to new alkoxyamines suitable for hydrosilylation reactions, to siloxane modified alkoxamines and to siloxane modified polymers as well as to their use. The alkoxamines are compounds of formula (I) or (II) wherein A is a group capable of forming a stable free nitroxyl radical A. which is bound via its oxygen atom to the carbon atom; R.sub.1 and R.sub.2 independently of one another are hydrogen, C.sub.1-C.sub.18-alkyl, C.sub.3-C.sub.8cycloalkyl or phenyl which are unsubstituted or substituted by NO.sub.2, halogen, amino, hydroxy, cyano, carboxy, C.sub.1-C.sub.4alkoxy, C.sub.1-C.sub.4alkylthio, C.sub.1-C.sub.4alkylamino or di(C.sub.1-C.sub.4alkyl)amino; R.sub.3, R.sub.4 and R.sub.5 independently of one another are hydrogen or C.sub.1-C.sub.18alkyl or phenyl; or R.sub.3 and R.sub.5 together with the linking group C.dbd.C form a 5 to 12 membered ring; R.sub.6 is X hydrogen or C.sub.1-C.sub.l8alkyl or phenyl; X is O, NH or NR.sub.7, wherein R.sub.7 is C.sub.1-C.sub.18alkyl, C.sub.3-C.sub.

Abstract: Modified epoxy resins comprising the reaction product of a cycloaliphatic, polycyclic and/or aromatic biomass derived compound and an epoxy resin are disclosed. Aqueous dispersions and coatings comprising these reaction products are also disclosed.

Abstract: A method and an apparatus of discharging polymer from a continuously operated gas phase reactor, wherein at least one monomer is polymerized in a bed containing active catalyst formed by catalyst and polymer particles suspended in a fluid, the bed defining a fluidized bed level in said reactor. The invention comprises continuously withdrawing polymer powder from the reactor; and adjusting the discharge rate of the polymer powder so as to maintain a constant bed level during polymerization. By means of the invention the discharge of the polymer can be made truly continuous without any disturbance of the polymerization. The rate of withdrawn polymer can be flexibly adjusted depending on the progress of the polymerization and it can also easily be scaled up if the capacity of the reactor is increased.

Abstract: The present invention relates to a method for reducing/suppressing sheeting or agglomerates during polymerization of olefins, especially during the fluidized bed gas phase polymerization of olefins. In particular, the present invention relates to a method for reducing/suppressing sheeting or agglomerates during the product grade transition and/or catalyst transitions occurring polymerization of olefins.

Abstract: In a process for producing a propylene-based olefin homopolymer or copolymer, a monomer composition comprising propylene is contacted with a polymerization catalyst system under homogeneous polymerization conditions (such as solution, supersolution or supercritical conditions), wherein the polymerization catalyst system includes an activator and a bridged bis-indenyl transition metal (group 4) compound substituted with a carbazole (unsubstituted or substituted) at the 4 position.

Abstract: A radiation-sensitive resin composition is provided which has high transparency to radiation, excelling in basic properties as a resist such as sensitivity, resolution, and pattern shape, and, in particular, a high resolution radiation-sensitive resin composition providing a wide DOF and excelling in LER. Also provided are a polymer which can be used in the composition and a novel compound useful for synthesizing the polymer. The novel compound is shown by the following formula (2), wherein R4 represents a methyl group, a trifluoromethyl group, or a hydrogen atom, at least one of the Rfs represents a fluorine atom or a linear or branched perfluoroalkyl group having 1 to 10 carbon atoms, A represents a divalent organic group or a single bond, G represents a divalent organic group having a fluorine atom or a single bond, Mm+ represents a metal ion or an onium cation, m represents an integer of 1 to 3, and p is an integer of 1 to 8.

Abstract: Processes for the production of polymers by emulsion polymerization of olefinically unsaturated monomers, in which olefinically unsaturated esters corresponding to formula (I): HOOC—CH?CH—COO—(BO)z(PO)y(EO)xR1??(I) in which R1 is an alkyl group or alkenylphenol group containing 8 to 24 carbon atoms, BO is a butylene oxide unit, PO is a propylene oxide unit and EO is an ethylene oxide unit and the indices x, y and z independently of one another stand for 0 or for numbers of 1 to 50, with the proviso that at least one of the indices x, y and z is not 0, the carboxyl group of the compounds (I) being completely or partly present in neutralized form and the C?C double bond being cis- or trans-configured; are used as copolymerizable emulsifiers.

Abstract: A water-based coated-type vibration damping material uses a styrene-butadiene copolymer emulsion as a resin emulsion and a calcium carbonate as an inorganic filler. The water-based coated-type vibration damping material limits a blending amount of a glycol to 2% by weight or less. In case of making a coated layer by such water-based coated-type vibration damping material, there is no blister generation observed after a hot water immersion of 168 hours (7 days), after a hot water immersion of 336 hours (14 days) and after a hot water immersion of 1000 hours, either.

Abstract: The present invention discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; (2) initiating polymerization of said monomer within the aqueous polymerization medium to produce a latex of an unsaturated polymer; (3) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer.

Abstract: A resin is based on ketones and aldehydes and is prepared in methanol or ethanol in the presence of a phase transfer catalyst. The resin features a very broad solubility and low intrinsic color.

Abstract: A process is described for preparation of oxymethylene homo- and copolymers. This encompasses heterogeneous polymerization of a monomer which forms oxymethylene groups in the presence of an acetal of formaldehyde and of an initiator for cationic polymerization, followed by the deactivation of the polymer in a homogeneous phase via treatment with a basic aprotic solvent or with an aprotic solvent which comprises a base. Oxymethylene homopolymers with very high stability are also described.

Abstract: Described are LCD films or sheets comprising polyester compositions comprising polyesters which comprise (a) a dicarboxylic acid component having terephthalic acid residues; optionally, aromatic dicarboxylic acid residues or aliphatic dicarboxylic acid residues or ester residues thereof; 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues.

Abstract: Described are outdoor signs comprising polyester compositions comprising polyesters which comprise (a) a dicarboxylic acid component having terephthalic acid residues; optionally, aromatic dicarboxylic acid residues or aliphatic dicarboxylic acid residues or ester residues thereof; 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues.

Abstract: A monomer with a chromophore group represented by Formula (I): wherein AR1 represents a substituted or unsubstituted aromatic group; AR2 represents a substituted or unsubstituted aromatic group or a substituted or unsubstituted alkyl group; and R represents a substituted or unsubstituted alkyl group, with the proviso that one of R, AR1, and AR2 has a substituent with a polymerizable functional group. The monomer can be advantageously used to prepare polymeric dispersants for pigment dispersion, especially inkjet inks.

Abstract: Disclosed is a process for preparing copolymer dispersions made of alkylene oxides and glycidyl ethers according to formula (I) in which R1 is hydrogen or a C1-C4-alkyl radical, R2 and R4 are an alkyl or aryl radical having 1 to 30 carbon atoms, and R3 is an alkyl or aryl radical having 1 to 50 carbon atoms, which may also contain heteroatoms. A is an alkylene unit having 2 to 6 carbon atoms. In formula (1), x is a number from 0 to 10, y is a number from 0 to 10, n is a number from 0 to 100, k is a number from 1 to 100, R5 is an acid group or hydrogen, and m is a number from 1 to 500, with the proviso that (y+n) must be at least 1.

Abstract: The present invention relates to a method for preparing a high molecular weight latex resin powder, and more precisely, a method for preparing a high molecular weight latex resin powder which comprises the steps of preparing a slurry by coagulating a high molecular weight latex; stabilizing the slurry; and aging the stabilized slurry, and is characterized by the direct addition of a colloidal modifier to the high molecular weight latex reactant during the preparation of the slurry. According to the present invention, the high molecular weight latex resin powder prepared by the method of the present invention has excellent particle size distribution, apparent specific gravity, caking property and thermo-stability, even with high solid content, compared with the conventional slow coagulation, and at the same time the method has an advantage of reducing energy costs and waste water generation.

Abstract: The invention provides relatively short immunogenic peptides derived from CD19 and CD20 antigens, and biologically active variants thereof, which elicit an immune response. Nucleic acids encoding the immunogenic peptides and antibodies specific for the peptides are also provided. The immunogenic peptides can be included in pharmaceutical compositions, such as cancer vaccines, and used for the treatment of cancer.

Abstract: Specific fragments of vasostatin are disclosed. These fragments are of use in methods of stimulating the proliferation or survival of a hematopoietic cell exposed to a chemotherapeutic agent or irradiation. Methods of stimulating the proliferation or survival of a hematopoietic cell using these fragments are also disclosed. In one embodiment, methods are disclosed for stimulating the growth or survival of a hematopoietic stem cell with a fragment of vasostatin, in the presence of a growth factor.

Abstract: The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-?B-dependent target gene expression in a cell.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: Compositions suitable for intranasal administration containing calcitonin, chlorobutanol, a pH of about 3.5, and sodium chloride, and an intranasal spray and a pharmaceutical delivery device thereof.

Abstract: Mammalian GLP-2 mimetibodies, polypeptides and nucleic acids are disclosed. Methods of utilizing the mimetibodies and polypeptides to treat GLP-2 related diseases are also disclosed.

Abstract: Disclosed herein are sweet proteins that are variants of Brazzein, and nucleotide sequences capable of expressing them. Through a replacement of a tyrosine residue at the C terminus in the naturally occurring Brazzein sequence, or the insertion of two residues (at least one being isoleucine, glycine or proline) before the N terminus of wild type Brazzein, sweetness potency, the taste profile and sweetness strength are improved.

Abstract: The present invention provides the enzyme and enzymatic procedures for cleaving the ? secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays.

Abstract: A method of diagnosing cancer comprising the identification of neoplastic molecular markers is disclosed. Tumor-related or neoplastic molecular markers are identified from samples taken from a subject and the molecular profile of those markers is determined. Based upon the neoplastic molecular marker profile of the subject, the tumor sub-type is ascertained and an appropriate treatment protocols initiated.

Abstract: A method for differentiation of osteoarthritis from rheumatoid arthritis and non-disease conditions in a sample, comprising measuring in the sample the concentration of human cartilage intermediate layer protein 2(CILP-2) in body fluids and more specifically, measuring in the sample the concentration of the N-terminal part of CILP-2 (2C1) or fragments thereof.

Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.

Abstract: The invention relates to G-CSF molecules having certain O-linked oligosaccharide structures.

Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.

Abstract: The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

Abstract: Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.

Abstract: The subject invention provides exciting new sources for surprising, new types of toxin complex (“TC”) proteins. The subject invention includes these new classes and types of TC proteins. The subject invention also includes polynucleotides that encode the subject proteins. The subject invention further provides vectors and cells comprising these polynucleotides. The subject invention also provides novel methods of controlling insects. The subject invention relates in part to the surprising discovery that new types of TC proteins can be obtained from a widely diverse phylogenetic spectrum of organisms including, most notably and surprisingly, eukaryotic fungus.

Abstract: The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.

Abstract: The invention provides anti-OX40L antibodies, and compositions comprising and methods of using these antibodies.

Abstract: The present invention relates to methods for the control of virulence of infectious bacteria by modulating the extra-cellular concentration of bacterial cell signalling molecules. Derivatives of cell signalling molecules are conjugated to suitable carrier proteins and used to isolate high affinity receptors recognising the native signal molecule(s). By binding to signalling molecules, the receptors reduce and maintain extra-cellular concentrations of signal molecules below the threshold level that would otherwise result in certain opportunistic pathogens adopting a virulent form, and can transform virulent organisms to non-virulent states. These receptors have applications for the treatment of individuals with susceptibility to infection, the treatment of patients with existing infections, in disease monitoring and management, and in related applications where the host for infection is an animal or plant.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.