Patents Issued in April 14, 2011
  • Publication number: 20110086740
    Abstract: A power transmission apparatus disposed includes: a motor for driving wheels, and transforms kinetic energy at the driving path to electrical energy; a normal close type clutch that includes an input and an output and is selectively set in an engaging state and a released state, wherein the clutch is normally set in the engaging state by a biasing member and is set in the released state when hydraulic pressure is applied; a hydraulic-pressure feeding device for supplying the adjusted hydraulic pressure to the clutch; and a control device for controlling the feeding device. When changing the clutch from the engaged state to the released state, if the difference between rotation numbers of the input and the output becomes equal to or larger than the predetermined value, the control device controls the feeding device to bring the clutch to a state just before the engaged state.
    Type: Application
    Filed: September 29, 2010
    Publication date: April 14, 2011
    Applicant: AISIN SEIKI KABUSHIKI KAISHA
    Inventors: Yoshihide SUZUKI, Hiroyuki INAGAKI
  • Publication number: 20110086741
    Abstract: A vehicle comprises a drive sub-system having an engine and a first motor and a generator sub-system having a transmission and a second motor. The transmission for the vehicle is driven with the first motor, the second motor and the engine individually and in combination such that the vehicle may selectively operate in a serial hybrid mode and a parallel hybrid mode.
    Type: Application
    Filed: October 7, 2010
    Publication date: April 14, 2011
    Applicant: ALTe
    Inventors: William J. DeFrank, Seong Jun Kim, Nam-Huan Thai-Tang, Albert W. Harrison
  • Publication number: 20110086742
    Abstract: An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 14, 2011
    Applicants: Madonna Rehabilitation Hospital, Board of Regents of the University of Nebraska
    Inventors: Judith M. Burnfield, Yu Shu, Adam P. Taylor, Thad W. Buster, Carl A. Nelson
  • Publication number: 20110086743
    Abstract: An apparatus and method permitting a user to perform a simulated climbing and full body exercise is provided. The design includes a frame and a pair of lever arms and a pair of foot platforms and a torso support. The frame is configured to place the operator's center of gravity in a position of falling away from the frame, lever arms, foot platforms and providing a torso support enabling the operator to be supported by hanging from the hands and supported by the feet and torso support. The frame may be rotated through varying angles from vertical permitting the operator's center of gravity to fall away from the frame and allow the operator to hang away from the frame further enhancing the climbing experience.
    Type: Application
    Filed: October 14, 2009
    Publication date: April 14, 2011
    Inventor: Brian Charles Stewart
  • Publication number: 20110086744
    Abstract: The current invention is an exercise apparatus and method adapted for use with a leg exercising machine, the exercise apparatus including a base, a support beam having a proximal end and a distal end, wherein the proximal end portion extends from the base. Further included in the exercise apparatus is an omni-directional movable joint element that is disposed adjacent to the distal end portion and a grasping arm, with the grasping arm being received within the omni-directional movable joint element, wherein the grasping arm is operational to have omni-directional movement relative to the support beam. Also included in the exercise apparatus is a dampening element that is disposed between the support beam and the grasping arm, the dampening element is operational to dampen the omnidirectional movement such that an individual using the leg exercising machine can grasp the arm for stability and support for a soft skeletal joint support.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Inventor: Alan Clifford Wilson
  • Publication number: 20110086745
    Abstract: The present invention includes a treadmill system including a support platform, a liquid tank, and a lift support structure connected to a treadmill assembly by a lifting mechanism. In general, the liquid tank and the lift, support structure including the treadmill assembly move horizontally relative to and independent of one another along the support platform to position the lift support structure away from or about the liquid tank. In addition, the treadmill assembly moves vertically relative to and independent of the lift support structure using the lifting mechanism to lower or raise the treadmill assembly within an interior of the liquid tank or exterior of the liquid tank. More importantly, the combination of the horizontal movement and the vertical movement of the treadmill assembly permits a mammal to step onto the treadmill assembly before the treadmill assembly is raised and then lowered into an interior of the liquid tank.
    Type: Application
    Filed: October 12, 2010
    Publication date: April 14, 2011
    Applicant: TRAILBLAZERS AQUATIC LLC
    Inventors: Marian Macartney, Peter Previte
  • Publication number: 20110086746
    Abstract: A resistance chair with wheels assists users with performing correct abdominal crunches by guiding the user's effort. The resistance chair includes a seat connected to a hinged back with back support that extends to support the user's back and assist in the crunch recovery following the crunch extension.
    Type: Application
    Filed: November 4, 2010
    Publication date: April 14, 2011
    Inventor: Johann B. VERHEEM
  • Publication number: 20110086747
    Abstract: A video game chair for enhancing the enjoyment of a video game includes a chair member formed of a horizontal seat portion with a backrest portion vertically extending therefrom. This is a chair that utilizes arm movement, torso movement, leg movement and finger movement to control video games. The chair's movement is under resistance which is variable to suit the needs of the person playing the game. This resistance allows for a video gamer to benefit from extreme cardio and bodybuilding workouts while having their mind “in the game”.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Inventor: Benjamin Karl Broderick
  • Publication number: 20110086748
    Abstract: A drum rotating device enables a drum and a driving device mounted in the drum to be supported with a simple structure and which reduces the possibility that the driving shaft of the driving device may be offset with respect to the rotation axis of the drum. The drum rotation device includes the drum and the driving device arranged to drive and rotate the drum. The drum includes an outer cylinder, an inner cylinder arranged inside the outer cylinder coaxially therewith, and a support wall arranged to connect the outer and inner cylinders to each other at an approximately intermediate portion in the axial direction. The outer and inner cylinders are substantially cylindrical. The driving device is fixed to a frame at one axial end. The driving shaft of the driving device extends through the drum and is rotatably supported by the frame through a bearing at the other axial end.
    Type: Application
    Filed: September 22, 2010
    Publication date: April 14, 2011
    Applicants: NIDEC SERVO CORPORATION, GLORY LTD.
    Inventors: Takeshi KIRIHARA, Takashi ANDO, Isao MIKI, Yoshikazu MITSUSADA
  • Publication number: 20110086749
    Abstract: A manufacturing machine for plastic containers having an upper and a lower portion with respective joining edges, comprising a first fixed base with an axle mounted thereto, a circular platform mounted upon the axle, and a plurality of welding stations mounted over the circular platform. Each welding station comprises a second fixed base that receives the lower portion of the container and a movable head having suction heads that receives the upper portion of the container therein, and it slides up and down upon a column mounted to the circular platform. The present invention further comprises a fusion station that acts upon the joining edges of the upper and lower portion and it comprises a hot plate that is positioned between the joining upper and lower edges and raises the temperature of the material, thus fusing the material. A robot loads new upper and lower portions into the welding station.
    Type: Application
    Filed: October 8, 2010
    Publication date: April 14, 2011
    Inventor: Manuel IGLESIAS RODRIGUEZ
  • Publication number: 20110086750
    Abstract: The present invention provides a cargo shipping crate having a base, four sides and a top cap, a first panel and a second panel. The first panel and the second panel form four sides of the crate. Each panel has a first, a second and a third subpanel. The first subpanel of the first panel is positioned to overlap the third subpanel of the second panel, and the second subpanel of the first and the second panel have substantially identical dimensions. The first subpanel of the first and the second panel have substantially identical dimensions, and the third subpanel of the first and the second panel have substantially identical dimensions. The top cap has four flaps, each of the four flaps are rotatable to a position superjacent a subpanel.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 14, 2011
    Inventor: David Goodrich
  • Publication number: 20110086751
    Abstract: An apparatus for securing an end cap including an end cap flange to a shell including a shell flange by forming a lip portion including the end cap flange and the shell flange into a lock seam portion in which the end cap flange and the shell flange are engaged with each other. The apparatus includes an elongate tool element rotatable about the central axis, for receiving the end cap thereon. The apparatus also includes a number of roller subassemblies for forming the lip portion into the lock seam portion. Each roller subassembly includes a forming roller engageable with the lip portion while the tool element rotates. Each roller subassembly also includes an arm on which the forming roller thereof is rotatably mounted, and a support mechanism for positioning the arm to engage the forming roller with the lip portion.
    Type: Application
    Filed: September 5, 2008
    Publication date: April 14, 2011
    Inventors: Mohamed Gharib, Michael W. Van Heurn
  • Publication number: 20110086752
    Abstract: A blood separation chamber for rotation about an axis comprises a low-G wall and a high-G wall extending about the axis in a spaced apart relationship to define between them a separation channel. The separation channel includes axially spaced first and second ends. The first end of the separation channel defines at least one generally arcuate recessed region and at least one radial wall within the recessed region sized and positioned so as to aid in balancing the blood separation chamber during rotation about the axis.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Inventor: Mark J. Brierton
  • Publication number: 20110086753
    Abstract: A system for polishing a float glass used for liquid crystal displays includes a lower unit configured to rotate a float glass to be polished, a head assembly configured to be rotatable in contact with the float glass, and a moving unit configured to move the head assembly in a horizontal direction, wherein the head assembly includes at least two heads that are rotatable, respectively.
    Type: Application
    Filed: October 7, 2010
    Publication date: April 14, 2011
    Inventors: Won-Jae Moon, Hyung-Young Oh, Sang-Oeb Na
  • Publication number: 20110086754
    Abstract: Ceramic materials with relatively high resistance to wetting by various liquids, such as water, are presented, along with articles made with these materials, methods for making these articles and materials, and methods for protecting articles using coatings made from these materials. One embodiment is an article comprising a material that is transparent to electromagnetic radiation of at least one type selected from the group consisting of ultraviolet radiation, visible light, and infrared radiation. The material comprises a primary oxide and a secondary oxide. The primary oxide comprises cerium or hafnium. The secondary oxide comprises (i) praseodymium or ytterbium, and (ii) another cation selected from the group consisting of the rare earth elements, yttrium, and scandium.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 14, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Molly Maureen Gentleman, James Anthony Ruud, Mohan Manoharan
  • Publication number: 20110086755
    Abstract: A catalyst for hydrocracking of heavy oil which comprises a support comprising crystalline aluminosilicate and a porous inorganic oxide excluding the crystalline aluminosilicate and an active metal supported on the support, wherein (a) the support comprises the crystalline aluminosilicate in an amount of 18% by mass or greater and smaller than 45% by mass and the porous inorganic oxide in an amount exceeding 55% by mass and of 82% by mass or smaller based on a sum of the amount of the crystalline aluminosilicate and the amount of the porous inorganic aluminosilicate, (b) the active metal is at least one metal selected from molybdenum, tungsten and nickel, and (c) the distribution of pores in the catalyst for hydrocracking of heavy oil is such that a volume of pores having a diameter of 500 to 10,000 ? is 10% or smaller and a volume of pores having a diameter of 100 to 200 ? is 60% or greater based on a volume of entire pores having a diameter of 50 to 10,000 ?.
    Type: Application
    Filed: March 17, 2009
    Publication date: April 14, 2011
    Inventors: Akira Iino, Kazuhiro Inamura
  • Publication number: 20110086756
    Abstract: A method of preparing the electronic material called silicon intercalated epitaxial monolayer graphene comprises the steps of growing large scale high-quality graphene on metal surface, depositing silicon on the prepared epitaxial graphene and annealing to high temperature to intercalate the silicon to the interface of graphene and metal surface. Depending on the quantity of the silicon deposited on the graphene surface, the numbers of the silicon layers on the interface can be controlled and adjusted.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 14, 2011
    Inventors: Hong-jun Gao, Yi Pan, Min Gao, Jinhai Mao, Li Huang, Haitao Zhou, Yeliang Wang, Haiming Guo, Shixuan Du
  • Publication number: 20110086757
    Abstract: A deoxidizer includes a porous body of fluorite-type cerium oxide represented by CeOx (where x is a positive number smaller than 2) and having a reversible oxygen deficiency. The deoxidizer has a specific surface area of 0.6 to 1.8 m2/g and a pore median diameter of 1.6 to 5.3 ?m. The cerium oxide used for the deoxidizer is produced by: firing a cerium-containing salt in the atmosphere at 500° C. to 1400° C. for 1 to 20 hours, to produce fluorite-type cerium oxide composed of a porous body; and firing the cerium oxide at 700° C. to 1100° C. for 1 to 3 hours in a reducing atmosphere having a hydrogen concentration equal to or above the lower explosive limit, to remove oxygen from the cerium oxide and produce the fluorite-type cerium oxide represented by CeOx and having a reversible oxygen deficiency.
    Type: Application
    Filed: July 6, 2009
    Publication date: April 14, 2011
    Applicant: MITSUI MINING & SMELTING CO., LTD.
    Inventors: Kazuya Kinoshita, Yuichi Senoo, Yousuke Shibata, Isamu Yashima
  • Publication number: 20110086758
    Abstract: The present invention relates to a fungicidal compositions comprising 3?-bromo-2,3,4,6?-tetramethoxy-2?,6-dimethylbenzophenone.
    Type: Application
    Filed: February 20, 2009
    Publication date: April 14, 2011
    Applicant: BASF SE
    Inventors: Markus Gewehr, Jens Bruns, Maria Scherer, Egon Haden
  • Publication number: 20110086759
    Abstract: The present invention relates to substituted pyrimidine derivatives of as well as N-oxides and agriculturally acceptable salts thereof, and their use to control undesired plant growth, in particular in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N-oxides and/or salts as well as mixtures of the same with one or more further active ingredient (such as, for example, an herbicide, fungicide, insecticide and/or plant growth regulator) and/or a safener.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 14, 2011
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Mary Bernadette Aspinall, William Roderick Mound, Jeffrey Steven Wailes, William Guy Whittingham, John Williams, Caroline Louise Winn, Worthington Paul Antony
  • Publication number: 20110086760
    Abstract: Agricultural suspension in oil of Sulfonylureas and combinations with Fluroxypyr or other appropriate herbicides or agrochemicals are disclosed. The resulting formulations have improved stability regarding physicochemical properties of the formulation, as well as stability of the active ingredients allowing to make mixtures not yet available in the market.
    Type: Application
    Filed: May 28, 2008
    Publication date: April 14, 2011
    Inventors: Victor Casana Giner, Miguel Gimeno Sierra, Bárbara Gimeno Sierra
  • Publication number: 20110086761
    Abstract: The present invention relates to fungicidal compositions and their use for controlling oomycete pathogen induced disease or diseases in one or more plants.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 14, 2011
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Norman R. Pearson, Lei Liu, Robert J. Ehr, John M. Atkinson
  • Publication number: 20110086762
    Abstract: The present invention relates to novel 4?4?-dioxaspiro-spirocyclically substituted tetramates of the formula (I) in which A, B, G, m, n, W, X, Y and Z to a plurality of processes for their preparation and to their use as pesticides and/or herbicides. The invention also provides selectively herbicidal compositions comprising firstly the 4?4?-dioxaspiro-spirocyclically substituted tetramates and secondly a crop plant compatibility-improving compound. The present invention also relates to novel water-soluble concentrates of 4?4?-dioxaspiro-spirocyclically substituted tetramates and their enols, to processes for preparing these formulations and to their use as pesticides and/or herbicides.
    Type: Application
    Filed: March 16, 2009
    Publication date: April 14, 2011
    Applicant: Bayer CropScience AG
    Inventors: Reiner Fischer, Rolf Pontzen, Ronald Vermeer, Eva-Maria Franken, Olga Malsam, Leonardo Pitta, Udo Reckmann
  • Publication number: 20110086763
    Abstract: Methods for multiplex amplification of target nucleic acid sequences are provided.
    Type: Application
    Filed: July 27, 2009
    Publication date: April 14, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: John Bodeau, Stephen Gunstream, Mark Oldham
  • Publication number: 20110086764
    Abstract: The present invention provides a single tube multiplex assay for distinguishing basmati from non-basmati rice varieties, and thereby identifying the adulteration of basmati rice varieties. The present invention further provides a method for quantifying adulteration in basmati rice varieties. The present invention also provides a kit for performing a multiplex assay for distinguishing basmati from non-basmati rice varieties. The kit may comprise a primer directed to an SSR loci, appropriate reagents for PCR, and optionally, a package insert for conducting the assay.
    Type: Application
    Filed: July 23, 2010
    Publication date: April 14, 2011
    Applicant: CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS(CDFD)
    Inventors: JAVAREGOWDA NAGARAJU, SUNIL ARCHAK
  • Publication number: 20110086765
    Abstract: Method for molecular characterization of a carcinoma including: (i) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a first group determining expression level of the polynucleotide from the first group to differentiate a tumor in which a lymph node has been invaded by a tumor cell from a tumor in which a lymph node has not been invaded by a tumor cell; (ii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a second group determining expression level of the polynucleotide from the second group to distinguish tumors sensitive to anthracycline from tumors insensitive to anthracycline; (iii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a third group determining expression levels of the polynucleotide from the third group to classify good and poor prognosis primary breast tumors.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 14, 2011
    Applicants: IPSOGEN, SAS, Institut Paoli-Calmettes
    Inventors: Francois Bertucci, Rémi Houlgatte, Daniel Birnbaum, Catherine Nguyen, Patrice Viens, Vincent Fert
  • Publication number: 20110086766
    Abstract: Device comprising: a first substrate; a plurality of first raised elements on the first substrate, the first raised elements mutually spaced apart by first channel regions on the first substrate, each of the first raised elements having a first distal end, the first distal ends forming a first array; hydrophobic molecules on the first raised elements; and primary reactive molecules on the first raised elements for generating hydrophilic reaction products. Techniques for utilizing the device.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 14, 2011
    Applicant: LUCENT TECHNOLOGIES, INC.
    Inventors: Joanna Aizenberg, Thomas Nikita Krupenkin, Oleksandr Sydorenko, Joseph Ashley Taylor
  • Publication number: 20110086767
    Abstract: Method for preparing the disaccharide ?-D-glucopyranosyl-(1?4)-2-N-acetyl-2-deoxy-?-D-glucopyranoside, comprising the step of using a mutant of a wild type glycoside hydrolase.
    Type: Application
    Filed: March 12, 2009
    Publication date: April 14, 2011
    Inventors: Laurence Mulard, Isabelle Andre, Elise Champion, Claire Moulis, Sandrine Morel, Pierre Monsan, Magali Remaud-Simeon, Karine Descroix
  • Publication number: 20110086768
    Abstract: Fusion proteins comprising a transferrin moiety and integrin binding domain and peptide libraries thereof are disclosed. The present invention includes a method of screening transferrin and integrin peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast.
    Type: Application
    Filed: December 7, 2007
    Publication date: April 14, 2011
    Applicant: BIOREXIS PHARMACEUTICAL CORPORATION
    Inventors: Andrew John Turner, Baiyang Wang
  • Publication number: 20110086769
    Abstract: Disclosed are methods and genotyping panels for detecting alleles, genomes, and transcriptomes in admixtures of two individuals.
    Type: Application
    Filed: December 22, 2009
    Publication date: April 14, 2011
    Applicant: Celula, Inc.
    Inventors: Arnold R. Oliphant, Kurt A. Krummel, Haichuan Zhang, Andrew S. Katz
  • Publication number: 20110086770
    Abstract: This invention relates to polypeptide libraries comprising polypeptides having a C-type lectin domain (CTLD) with a randomized loop region, as well as nucleic acid libraries comprising nucleic acid molecules encoding such polypeptides. The invention also relates to methods for generating the randomized polypeptides and the polypeptide libraries. The invention further relates to methods of screening the polypeptide and nucleic acid libraries based on the specific binding of the modified CTLDs to a target molecule of interest. The invention also relates to polypeptides derived from such libraries that bind to target molecules of interest.
    Type: Application
    Filed: February 10, 2010
    Publication date: April 14, 2011
    Inventors: Martha Wild, Anke Kretz-Rommel, Katherine S. Bowdish, Mark Renshaw
  • Publication number: 20110086771
    Abstract: Improved biochips comprise a matrix layer coupled to a substrate, wherein the matrix layer includes a plurality of ligands in a plurality of predetermined positions and wherein ligands bind to an anti-ligand disposed in a sample fluid. Preferred matrix layers are multi-functional matrix layers that reduce autofluorescence, incident-light-absorption, charge-effects, and/or surface unevenness of the substrate, and contemplated biochips may comprise additional matrix layers. Contemplated biochips may be useful in detection and/or quantification of various anti-ligands, including polypeptides, polynucleotides, carbohydrates, pharmacologically active molecules, bacterial or eukaryotic cells, and/or viruses.
    Type: Application
    Filed: August 27, 2010
    Publication date: April 14, 2011
    Applicant: AUTOGENOMICS, INC.
    Inventors: Vijay Mahant, Fareed Kureshy
  • Publication number: 20110086772
    Abstract: Multiplex (+/?) stranded analyses, such as array comparative genomic hybridization (aCGH), are provided for detecting chromosomal rearrangements associated with cancer and other diseases. For example, an illustrative multiplex array for CGH includes discrete plus (+) strand and minus (?) strand DNA probes, complementary to each other but separable on the CGH array. The minus (?) strand DNA probes recover diagnostic information lost to conventional microarrays, since many genes transcribe from the minus (?) strand. In an illustrative system, patient and control DNA samples are prepared for CGH by amplification and labeling using comprehensive primers that generate both plus (+) strands and minus (?) strands of DNA in the samples. The breakpoints of a translocated chromosome may be detected on a multiplex microarray by DNA probes of one polarity, while DNA copy number changes associated with the translocation region may be detected by corresponding DNA probes of the complementary polarity.
    Type: Application
    Filed: September 27, 2010
    Publication date: April 14, 2011
    Applicant: Signature Genomics Laboratories LLC
    Inventors: Lisa McDaniel, Blake Ballif, Roger Schultz, Brice Tebbs, Bassem Bejjani, Lisa Shaffer
  • Publication number: 20110086773
    Abstract: The invention provides for a diagnostic test to monitor cancer-specific genetic abnormalities to diagnose oral cell disorders and predict which patients might progress to cancer. Genetic abnormalities are detected by identification in chromosomal copy number of chromosome 3, chromosome 5 and chromosome 6 using FISH analysis of probes targeted to 3q and/or 5p and/or 11q.
    Type: Application
    Filed: October 8, 2010
    Publication date: April 14, 2011
    Applicant: NEODIAGNOSTIX, INC.
    Inventors: GREGORY ANTON ENDRESS, MADHVI UPENDER, ELIZABETH LIGHT, COLYN CARGILE CAIN
  • Publication number: 20110086774
    Abstract: The invention provides methods, compositions, kits and devices for the detection of proteins. In some embodiments, the invention allows for multiplexed protein detection.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 14, 2011
    Inventor: Dwayne L. Dunaway
  • Publication number: 20110086775
    Abstract: The invention relates to an isolated or recombinant Na+/H+ exchanger comprising an isolated or recombinant Na+/H+ exchanger, particularly to the PBO-4 Na+/H+ exchanger. Also disclosed is an isolated or recombinant protein component of an H+-gated channel which can be affected by extracellular Ca2+ concentration. In particular, the invention relates to PBO-5 and/or PBO-8 and/or a H|-gated channel composed of PBO-5 and PBO-8. The invention relates to compounds isolated from a vertebrate organism, wherein said compounds comprise at least a part of a H+-gated channel or Na+/H+ exchanger. The invention also relates to a method for identifying a component of a H+-gated channel in a vertebrate organism.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 14, 2011
    Inventors: Erik M. Jorgensen, Asim A. Beg, Paola Nix
  • Publication number: 20110086776
    Abstract: The present invention concerns methods and compositions usable for diagnosing Alzheimer's disease in mammals, in particular humans. It particularly describes serum markers for Alzheimer's disease and their use in diagnostic methods. It also concerns tools and/or kits usable for implementing these methods (reagents, probes, primers, antibodies, chips, cells, etc.), their preparation and their use. The invention is usable to detect the presence or progression of Alzheimer's disease in mammals, including in the early phase, as well as for predicting the efficacy of an Alzheimer's disease treatment.
    Type: Application
    Filed: March 30, 2009
    Publication date: April 14, 2011
    Applicant: EXONHIT THERPEUTICS SA
    Inventors: Anne-Charlotte Jarrige-Le Prado, Pascale Beurdeley, Diego Pallares, Fabien Rouet, Laurent Bracco
  • Publication number: 20110086777
    Abstract: The present invention relates to a method for evaluating the level of risk for a subject to develop autism, or an autism spectrum disorder, which method comprises determining the number of risk alleles in autism-associated gene loci in a sample of a subject, wherein the more risk alleles are detected within said gene loci combined, the more increased is the risk of developing autism or an autism-spectrum disorder.
    Type: Application
    Filed: June 12, 2009
    Publication date: April 14, 2011
    Applicant: Integragen
    Inventors: Jérôme Carayol, Frédéric Tores, Jörg Hager
  • Publication number: 20110086778
    Abstract: An enhanced microplate can include a base having a footprint with a length of 5 127.76 mm±1 mm and a width of 85.48 mm±1 mm. The base can be configured for an array of microwells having a base being configured for an array of micro wells such that there are ax rows along the width and ?bx? columns along the length, where a is 8 or 9, b is 12, 13 or 14 provided that when b is 12, a is 9, and x is 0.5 or a positive integer. These enhanced microplates can be used to effectively increase throughput, decrease analysis time, and can be readily integrated into existing systems.
    Type: Application
    Filed: October 11, 2010
    Publication date: April 14, 2011
    Inventors: Mark G. Herrmann, Tanya M. Sandrock
  • Publication number: 20110086779
    Abstract: Arrays of protein-capture agents useful for the simultaneous detection of a plurality of proteins which are the expression products, or fragments thereof, of a cell or population of cells in an organism are provided. A variety of antibody arrays, in particular, are described. Methods of both making and using the arrays of protein-capture agents are also disclosed. The invention arrays are particularly useful for various proteomics applications including assessing patterns of protein expression and modification in cells.
    Type: Application
    Filed: November 19, 2010
    Publication date: April 14, 2011
    Applicant: Zyomyx, Inc.
    Inventors: Peter Wagner, Steffen Nock, Dana Ault-Riche, Christian Itin
  • Publication number: 20110086780
    Abstract: A system, including method and apparatus, for forming an array of emulsions. The system may include a plate providing an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation. Each set of wells, in turn, may include (1) at least one first input well to receive a continuous phase, (2) a second input well to receive a dispersed phase, and (3) an output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase.
    Type: Application
    Filed: December 8, 2010
    Publication date: April 14, 2011
    Applicant: QUANTALIFE, INC.
    Inventors: Billy Wyne Colston, JR., Benjamin Joseph Hindson, Kevin Dean Ness, Donald Arthur Masquelier
  • Publication number: 20110086781
    Abstract: The formation of arrays of fullerene nanotubes is described. A microscopic molecular array of fullerene nanotubes is formed by assembling subarrays of up to 106 fullerene nanotubes into a composite array.
    Type: Application
    Filed: August 22, 2006
    Publication date: April 14, 2011
    Applicant: William Marsh Rice University
    Inventors: Richard E. Smalley, Daniel T. Colbert, Hongjie Dai, Jie Liu, Andrew G. Rinzler, Jason H. Hafner, Ken Smith, Ting Guo, Pavel Nikolaev, Andreas Thess
  • Publication number: 20110086782
    Abstract: Controlling the formation of crystalline hydrates in various fluid systems, most notably, gas and oil transmission pipeline systems by contacting the systems with certain polymers or polymers associated with solid particles. The polymers useful are chelating polymers capable of interacting with charged gaseous molecules such as carbon dioxide, by removing the carbon dioxide, or more practically by scavenging for the carbon dioxide, to prevent the methane or ethane hydrate structures from forming since they require carbon dioxide to stabilize their structures.
    Type: Application
    Filed: December 11, 2010
    Publication date: April 14, 2011
    Inventor: David Graham
  • Publication number: 20110086783
    Abstract: An air drilling misting fluid is provided and the fluid comprises: a continuous liquid phase solution comprising syrup, syrup solids and a first liquid medium, the syrup and syrup solids are derived from a group consisting essentially of agave syrup, barley syrup, sugar syrup, beets syrup, birch syrup, rice syrup, cane syrup, chocolate syrup, coconut syrup, corn syrup, date syrup, fruit syrup, golden syrup, high fructose corn syrup, inverted sugar syrup, karo syrup, citrus fruit syrup, maple syrup, molasses, Muscavado syrup, palm syrup, rice syrup, sorghum syrup, Turbinado syrup, vanilla syrup and mixtures and blends thereof; and a second liquid medium.
    Type: Application
    Filed: October 12, 2010
    Publication date: April 14, 2011
    Inventors: Jerry Rayborn, SR., Dan M. DeLaRosa
  • Publication number: 20110086784
    Abstract: A lubricant containing one or more compounds selected from the keto compounds of general formula 1 in which R1, R2 and X have the indicated significance.
    Type: Application
    Filed: November 14, 2008
    Publication date: April 14, 2011
    Inventors: Rudolf Eidenschink, Holger Kretzschmann
  • Publication number: 20110086785
    Abstract: The present invention provides a grease composition for automobile wheel bearings, which contains (a) an urea thickener represented by general formula (1); R1—NHCONH—R2—NHCONH—R3 (wherein R1 and R3 may be the same or different from each other and are each independently an aromatic hydrocarbon group having 6 to 12 carbon atoms, and R2 represents an aromatic hydrocarbon group having 6 to 15 carbon atoms); (b) an organic molybdenum compound; and (c) a base oil. The composition of the present invention can extend the flaking life and lubrication life, and reduce the fretting wear.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 14, 2011
    Applicants: NTN CORPORATION, KYODO YUSHI CO., LTD.
    Inventors: Kazunori KUBOTA, Makoto OISHI
  • Publication number: 20110086786
    Abstract: A slurry composition for use as a lubricant and/or a stable suspension medium to suspend inert organic or inorganic particles which is an aqueous or polar solvent carrier containing gel particles as a lubricating and suspending agent for inert organic or inorganic particles. The composition can contain inorganic salts to provide additional electrostatic repulsion.
    Type: Application
    Filed: September 23, 2009
    Publication date: April 14, 2011
    Inventor: Irl E. Ward
  • Publication number: 20110086787
    Abstract: A lubricating oil composition having superior storage stability and load-carrying effect is disclosed. The composition comprises four components: (1) an alkali metal borate; (2) an oil-soluble sulfur compound; (3) a trialkyl hydrogen phosphite; and (4) a mixture of greater than 50% neutralized acidic phosphates that are essentially free of monothiophosphates.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 14, 2011
    Inventors: John A. Zakarian, Michael J. Haire
  • Publication number: 20110086788
    Abstract: The present invention relates to benefit agent containing delivery particles, compositions comprising said particles, and processes for making and using the aforementioned particles and compositions. When employed in compositions, for example, cleaning or fabric care compositions, such particles increase the efficiency of benefit agent delivery, there by allowing reduced amounts of benefit agents to be employed. In addition to allowing the amount of benefit agent to be reduced, such particles allow a broad range of benefit agents to be employed.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 14, 2011
    Inventors: Johan Smets, Jiten Odhavji Dihora, An Pintens, Sandra Jacqueline Guinebretiere, Adam Keith Druckrey, Peggy Dorothy Sands, Nianxi Yan
  • Publication number: 20110086789
    Abstract: The present invention relates to liquid personal care composition comprising both low levels of specific fatty isethionate product (e.g., less than 4%) and low overall fatty acid content (less than 4%) which, quite surprisingly, maintain excellent foaming profile relative to identical composition having high overall fatty acid content.
    Type: Application
    Filed: October 12, 2009
    Publication date: April 14, 2011
    Applicant: CONOPCO, INC., D/B/A UNILEVER
    Inventors: Liang Sheng Tsaur, Virgilio Barba Villa