Abstract: The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.

Abstract: The invention is a method of removing methyl iodide from an alkane distillation bottoms stream of an acetic acid production process. The method comprises contacting the alkane distillation bottoms stream in the liquid phase with a phosphine or a phosphine-functionalized support, and recovering a treated alkane distillation bottoms stream having a reduced methyl iodide content.

Abstract: A process for producing acetic acid comprising the steps of reacting carbon monoxide and at least one of methanol and a methanol derivative in a first reactor under conditions effective to produce a crude acetic acid product; separating the crude acetic acid product into at least one derivative stream, at least one of the at least one derivative stream comprising residual carbon monoxide; and reacting at least a portion of the residual carbon monoxide with at least one of methanol and a methanol derivative over a metal catalyst in a second reactor to produce additional acetic acid.

Abstract: Provided are fluorinated oxy-carboxylic acids, derivatives of oxy-carboxylic acids, and methods of preparing oxy-carboxylic acids and derivatives thereof.

Abstract: Phenylurea compounds of formula (I): are inhibitors of the enzyme SOAT-1. Cosmetic and pharmaceutical compositions containing them are useful for treating various disorders, such as acne, or have cosmetic applications. An exemplary species is 1-[1-(biphenyl-2-ylamino)cyclopentylmethyl]-3-(2,6-diisopropylpheny)urea.

Abstract: The present invention relates to 3-substituted phenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to a composition for this purpose, comprising the phenoxyamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.

Abstract: Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.

Abstract: The invention relates to a process for the preparation of cyclopropyl benzyl ketone compounds of formula (II) wherein R1 represents fluorine or chlorine atom or C1-4 alkoxy group, by the reaction of a Grignard reagent, obtained from the reaction of compound of formula (V), wherein X represents chlorine or fluorine atom, with the compound of formula (IV), wherein R2 represents C1-4 alkyl group, having a straight or branched chain. The process can be applied preferably on industrial scale. Compound of formula (II), wherein R represents a fluorine atom in position 2 is an intermediate of the preparation process of prasugrel, which is a platelet inhibitor used in the therapy.

Abstract: The present invention relates to [1] a process for producing a 2-alkyl-2-cycloalken-1-one represented by the following general formula (2), which includes the step of subjecting a 2-(1-hydroxyalkyl)cycloalkan-1-one to dehydration and isomerization in the co-existence of an acid and a platinum group metal catalyst, and [2] a process for producing an alkyl(3-oxo-alkylcycloalkyl)acetate which is useful as a perfume material, using the 2-alkyl-2-cycloalken-1-one: wherein n is an integer of 1 or 2; and R1 and R2 are each independently a hydrogen atom or an alkyl group having 1 to 8 carbon atoms with the proviso that R1 and R2 may form a ring through a carbon atom adjacent thereto.

Abstract: The invention provides a process for the preparation of a carbonyl compound in high efficiency by oxidizing an alcohol. The process for the preparation of a carbonyl compound of the present invention includes a step of oxidizing an alcohol in the presence of a compound of the formula (I) or a derivative or a salt thereof, and an oxidant, wherein R1 and R2 independently represent hydrogen, a halogen, a nitro or acidic group, or an alkyl or alkoxy group, each of which optionally has a substituent, or R1 and R2 combine the two carbon atoms to which they are boned to form an aromatic ring.

Abstract: The invention relates to a method for producing aldehyde functional compounds by a cross-metathesis reaction of an olefinic compound having at least one hydroxy group and at least one C—C double bond with at least one at least monounsaturated fatty acid or at least one at least monounsaturated fatty acid derivative, in the presence of a metathesis catalyst at a maximum temperature of 180° C. and in the presence of at least one reagent that acts as a protective group-forming compound in relation to the aldehyde group of the aldehyde functional compounds.

Abstract: Disclosed is a process for the isomerization of 2,2,4,4-tetraalkylcyclobutane-1,3-diols, such as 2,2,4,4-tetramethylcyclobutane-1,3-diol, by contacting the diol with a supported ruthenium catalyst in the presence of hydrogen at elevated pressures and temperatures. The process is carried under conditions in which there is no net production of 2,2,4,4-tetraalkylcyclobutane-1,3-diol. The process may be carried out in the presence or absence of a solvent and in the liquid or vapor phase.

Abstract: The present invention relates to a method of producing neopentyl glycol by addition of isobutyraldehyde and formaldehyde in the presence of a tertiary alkylamine as catalyst to give the hydroxypivalinaldehyde with subsequent liquid phase hydrogenation in the presence of a nickel catalyst at a temperature of 80 to 180° C. and at a pressure of 6 to 18 MPa in the presence of an aliphatic alcohol and in the presence of water.

Abstract: A process to convert glycerin into propylene glycol and purifying the produced propylene glycol is described. The glycerin-based propylene glycol production requires only one process step compared to petroleum/natural gas-based propylene glycol production requires multiple process steps, and thus represents a cost savings.

Abstract: Disclosed are methods for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3CHXCH2X??(I) to at least one compound of formula (II) CF3CZCHZ??(II). where X is independently Cl, Br, I or F, and Z independently is H or F. In certain preferred embodiments, each Z is different.

Abstract: To provide processes for efficiently and economically producing 2-chloro-1,1,1,2-tetrafluoropropane (R244bb) and 2,3,3,3-tetrafluoropropene (R1234yf) in an industrially practical manner. A process for producing 2-chloro-1,1,1,2-tetrafluoropropane, which comprises a chlorination step of reacting 1,2-dichloro-2-fluoropropane and chlorine in the presence of a solvent under irradiation with light to obtain 1,1,1,2-tetrachloro-2-fluoropropane, and a fluorination step of reacting the 1,1,1,2-tetrachloro-2-fluoropropane obtained in the chlorination step and hydrogen fluoride in the presence of a catalyst to obtain 2-chloro-1,1,1,2-tetrafluoropropane, and a process for producing 2,3,3,3-tetrafluoropropene, which comprises dehydrochlorinating it in the presence of a catalyst.

Abstract: A process for recovering benzene, the process including: feeding hydrogen and a hydrocarbon fraction comprising benzene, components lighter than benzene, components heavier than benzene, and diolefins to a catalytic distillation reactor system comprising at least one reaction zone comprising a hydrogenation catalyst; concurrently in the catalytic distillation reactor system: contacting the diolefins and hydrogen in the presence of the hydrogenation catalyst to selectively hydrogenate at least a portion of the diolefins; and fractionating the hydrocarbon fraction to form a fraction comprising benzene and other C6 hydrocarbons, and a heavies fraction comprising C7+ hydrocarbons; recovering the heavies fraction from the first catalytic distillation reactor system as a bottoms fraction; and withdrawing the fraction comprising benzene and other C6 hydrocarbons from the catalytic distillation reactor system as a benzene concentrate fraction.

Abstract: The object of this invention is a suspension of metal nanoparticles with a mean size of between 1 and 20 nanometers, in at least one non-aqueous ionic liquid, whereby said suspension also contains at least one nitrogen-containing ligand, in which said metal nanoparticles comprise at least one transition metal in the zero valence state that is selected from among rhodium, ruthenium, iridium, nickel, and platinum by themselves or in a mixture and in which said nitrogen-containing ligand is selected from the group that is formed by the linear compounds that comprise at least one nitrogen atom, whereby the non-aromatic cyclic compounds comprise at least one nitrogen atom, the non-condensed aromatic compounds comprise at least one nitrogen atom, the condensed aromatic compounds comprise at least one group of two aromatic cycles that are condensed two by two, and at least one nitrogen atom, whereby the condensed aromatic compounds comprise at least 3 aromatic cycles and 1 nitrogen atom, and whereby the condensed ar

Abstract: The present invention relates to a process for producing light olefins from a synthesis gas with significantly improved conversion and selectivity for C2-C4 light olefins in general and propylene in particular, as compared to a conventional process, through a sequential two-step process comprising preparing olefin compounds from a synthesis gas in the presence of an iron catalyst by the Fischer-Tropsch reaction followed by cracking the olefin compounds in the presence of a zeolite catalyst.

Abstract: A process for producing propylene and 1-butene is disclosed. The process comprises dimerizing ethylene in the presence of a dimerization catalyst to produce a dimerization mixture comprising 1-butene and 2-butenes. The dimerization mixture is distilled to produce a 1-butene stream containing 1-butene and ethylene, a 2-butenes stream, and a heavy stream. The 2-butenes stream is reacted with ethylene in the presence of a metathesis catalyst to produce a metathesis mixture comprising propylene, ethylene, and 2-butenes. Propylene is separated from the metathesis mixture.

Abstract: A process for the alkylation of a benzene-containing refinery stream such as reformate with light refinery olefins which is capable of achieving high benzene conversion levels operates in a fixed bed of an MWW zeolite catalyst, preferably MCM-22, in single pass mode in the liquid phase at a relatively low to moderate temperatures with pressure maintained at a value adequate to ensure subcritical operation. High levels of benzene conversion with conversions of at least 90% and higher, e.g. 92% or 95% or even higher are achievable. A high octane product is produced, comprising mono-, di- and tri-alkylbenzenes with lesser levels of the tetra-substituted products. By operating with staged olefin injection, the end point of the alkylation product can be maintained at a low value while, at the same time, achieving high levels of benzene and olefin conversion.

Abstract: A renewable biofuel based on a highly efficient batch catalysis methodology for conversion of 1-butene to a new class of potential jet fuel blends. By tuning the catalyst and then using the dimer produced, the carbon use is about 95% or greater.

Abstract: A process for the production of olefins from at least one of an alcohol and ether, the process including: contacting at least one alcohol or ether with a hydrofluoric acid-treated amorphous synthetic alumina-silica catalyst under decomposition conditions to produce an olefin.

Abstract: The invention relates to a catalytic composition and to a process for selective methanization of carbon monoxide in hydrogen- and carbon dioxide-containing streams, wherein the active component used is ruthenium and the support material is a lanthanum-cerium-zirconium oxide, and to the use thereof in fuel cell systems.

Abstract: The present invention provides devices and methods for treating wounds. The devices may include polymer particles capable of absorbing fluid such as blood. When devices of the invention are exposed to fluid, the fluid may enter the device and cause the polymer particles to swell. Devices of the invention may also apply pressure on wound cavities to stop or restrict the flow of fluid. In some embodiments, the devices may comprise components to facilitate absorption of fluid throughout the device, such as wicking elements and/or multiple compartments. One or more of the devices can be placed directly in the wound cavity, or in a containment structure and then into the wound cavity.

Abstract: Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a predetermined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device.

Abstract: Stable odor controlling compositions, methods for incorporating the compositions, and disposable absorbent articles, which release perfume and subsequently are able to minimize odor caused from bodily fluids via the presence of an oil-in-water emulsion that serves as a carrier and preservation system for the perfume. The stable odor controlling emulsion compositions include an oil-in-water emulsion comprising: a) an aqueous phase comprising a modified starch and water; b) an oil phase comprising a perfume; c) an effective amount of a rheology modifier; d) an effective amount of a co-surfactant; and e) an effective amount of an antimicrobial agent; wherein said emulsion composition is applied to said article in the form of stable emulsion droplets having an median size of less than about 1 ?m and dries to form a discontinuous film.

Abstract: A method for correctly placing an absorbent article in the crotch portion of an undergarment having a crotch portion bounded on opposite sides by portions of curved leg openings. In one embodiment the method comprises the steps of providing an absorbent article having at least one indicator marker visible from the body-facing surface, the indicator marker disposed to indicate proper alignment of the absorbent article with respect to the curved leg openings; positioning the absorbent article in the crotch portion such that the indicator marker is aligned with at least one leg elastic of the curved leg openings; and, affixing the article to the crotch portion of the undergarment.

Abstract: The present invention relates to a system suitable for monitoring multiple leakage events such as wetting of a diaper or alike sanitary product. The system includes two or more than two electrodes that are supported in a spaced apart relationship and a liquid permeable substrate between the electrodes that lacks or has a low capacity for holding or storing liquid. In the event of liquid leakage, an electrical bridge connecting the electrodes can be formed by the liquid, and before the product becomes saturated liquid can freely drain from the permeable substrate and disconnect the electrodes. Upon further liquid leakage, electrical connection between the electrodes can be reformed indicating multiple liquid leakage events. In the situation where the sanitary product becomes saturated and liquid is prevented from draining from the permeable substrate, the electrical connection will continue, indicating that the sanitary product requires changing.

Abstract: An absorptive article in which a terminal section of a sensor is less likely to be damaged in production, packaging, and transportation. An output terminal (115) of a sensor member (110) is placed at a side end of a front edge (180) of a urine pad (100). The side end of the front edge (180) is constructed only from a front face sheet (105) and a rear face sheet (106). The front face sheet (105) and the rear face sheet (106) are not joined together and are separably arranged. When the urine pad (100) is not in use, the output terminal (115) is covered by the front face sheet (105) and the rear face sheet (106). In use, the front face sheet (105) and the rear face sheet (106) are separated in the thickness direction and the output terminal (115) of the sensor member (110) is exposed.

Abstract: The present invention is directed to hygiene articles comprising nanofibers. The nanofibers are made from a melt film fibrillation process with a polymer composition having a melt flow rate of less than about 400 decigram per minute. The nanofibers, having a diameter of less than 1 micron, must comprise a significant number of the fibers in one layer of the web contained by the hygiene article. The hygiene articles include diapers, training pants, adult incontinence pads, catamenials products such as feminine care pads and pantiliners, tampons, personal cleansing articles, personal care articles, and personal care wipes including baby wipes, facial wipes, and feminine wipes.

Abstract: An absorbent article having extensibility at waist panel is disclosed. The absorbent article includes a liquid pervious topsheet, an absorbent core disposed underneath the topsheet, and a chassis layer. A first or second waist panel includes a portion of the chassis layer. The chassis layer includes a plurality of spaced discontinuities regularly disposed in at least a portion of the first or second waist panel. The discontinuities are open to provide the chassis layer with extensibility in the transverse direction when the first or second waist panel is subjected to tension. The absorbent article also includes an extensibility controlling means to control the extensibility of the chassis layer.

Abstract: The present invention relates to a transgenic fish having at least one genomically integrated expression cassette containing a 5?-regulatory nucleotide sequence responsive to hormones, particularly estrogenic hormones, connected in a functional manner upstream of a nucleotide sequence encoding a reporter protein. The present invention further relates to methods of using the transgenic fish for various purposes, including, for example: (1) identifying estrogenic endocrine disruptors; (2) monitoring estrogen-like activity of test samples; (3) identifying anti-estrogenic endocrine disruptors; and (4) investigating the effects of endocrine disruptors on liver regeneration. Expression cassettes, host cells, and transgenic cells of aquatic animals are also disclosed.

Abstract: A novel maize variety designated X00A012 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00A012 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00A012 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00A012, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00A012. This invention further relates to methods for producing maize varieties derived from maize variety X00A012.

Abstract: The present invention provides methods for transforming monocot plants via a simple and rapid protocol, to obtain regenerated plants capable of being planted to soil in as little as 4-8 weeks. Associated cell culture media and growth conditions are also provided, as well as plants and plant parts obtained by the method. Further, a method for screening recalcitrant plant genotypes for transformability by the methods of the present invention is also provided. Further, a system for expanding priority development window for producing transgenic plants by the methods of the present invention is also provided.

Abstract: Soybean ubiquitin promoters is from the soybean SUBI-3 polyubiquitin gene and processes for expressing nucleic acids of interest in transgenic plants under the control of the soybean ubiquitin promoter pare described. Higher expression levels of the nucleic acids are achieved when the promoter is included.

Abstract: The present disclosure provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a promoter. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequence disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.

Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.

Abstract: The present invention discloses and claims stress-inducible plant promoters, DNA constructs with such promoters, transgenic plants containing such promoters and DNA constructs, isolated DNAs encoding such promoters, and methods of making and using such promoters, DNA constructs, transgenic plants, and isolated DNAs.

Abstract: The invention relates to the soybean variety designated A1024249. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024249. Also provided by the invention are tissue cultures of the soybean variety A1024249 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024249 with itself or another soybean variety and plants produced by such methods.

Abstract: The invention relates to the soybean variety designated A1024300. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024300. Also provided by the invention are tissue cultures of the soybean variety A1024300 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024300 with itself or another soybean variety and plants produced by such methods.

Abstract: The invention relates to the soybean variety designated A1024001. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024001. Also provided by the invention are tissue cultures of the soybean variety A1024001 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024001 with itself or another soybean variety and plants produced by such methods.

Abstract: A soybean cultivar designated 12421671 is disclosed. The invention relates to the seeds of soybean cultivar 12421671, to the plants of soybean cultivar 12421671, to the plant parts of soybean cultivar 12421671, and to methods for producing progeny of soybean cultivar 12421671. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 12421671. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 12421671, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 12421671 with another soybean cultivar.

Abstract: A potato cultivar designated ‘Linton’ is disclosed. The invention relates to the tubers of potato cultivar ‘Linton’, to the seeds of potato cultivar ‘Linton’, to the plants of potato ‘Linton’, to the plant parts of potato cultivar ‘Linton’ and to methods for producing a potato plant produced by crossing potato cultivar ‘Linton’ with itself or with another potato variety. The invention also relates to methods for producing a potato plant containing in its genetic material one or more transgenes and to the transgenic potato plants and plant parts produced by those methods. This invention also relates to potato cultivars or breeding cultivars and plant parts derived from potato variety ‘Linton’, to methods for producing other potato cultivars, lines or plant parts derived from potato cultivar ‘Linton’ and to the potato plants, varieties, and their parts derived from use of those methods.

Abstract: Basically, this invention provides for an inbred corn line designated NPFX7012, methods for producing a corn plant by crossing plants of the inbred line NPFX7012, with plants of another corn plant. The invention relates to the various parts of inbred NPFX7012, including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPFX7012, and plants produced by said methods.

Abstract: A novel maize variety designated X00B156 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00B156 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00B156 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00B156, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00B156. This invention further relates to methods for producing maize varieties derived from maize variety X00B156.

Abstract: A novel maize variety designated X13B627 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13B627 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13B627 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13B627, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13B627. This invention further relates to methods for producing maize varieties derived from maize variety X13B627.

Abstract: A novel maize variety designated X13B626 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13B626 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13B626 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13B626, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13B626. This invention further relates to methods for producing maize varieties derived from maize variety X13B626.

Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV032767. The invention thus relates to the plants, seeds and tissue cultures of the variety CV032767, and to methods for producing a corn plant produced by crossing a corn plant of variety CV032767 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV032767 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV032767.

Abstract: According to the invention, there is provided seed and plants of the corn variety designated CV552047. The invention thus relates to the plants, seeds and tissue cultures of the variety CV552047, and to methods for producing a corn plant produced by crossing a corn plant of variety CV552047 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV552047 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV552047.