Abstract: A patient support system includes independently adjustable end columns supporting a centrally hinged, jointed or breaking patient support structure. At least one column includes a powered rotation assembly. The patient support includes at least two sections. A coordinated drive system provides for both upwardly and downwardly breaking or jointed orientations of the two sections in various inclined and tilted positions. Cable, cantilevered and pull-rod systems are included.

Abstract: This disclosure relates to resilient side rails for medical tables. In some aspects, a side rail for a medical table includes an elongated body having a height and a width that are configured to be received by a medical accessory, and the elongated body is formed of a material having a modulus of elasticity that is about 50 gigapascals to about 150 gigapascals and a yield strength that is about 40×107 pascals to about 120×107 pascals.

Abstract: An apparatus for facilitating tracheal intubation on an obese patient has a base section (1), a head section (11) attached to the base section (1) and a pad (2) removably positioned on the head section (11). The base section (1) receives a portion of an obese patient's back. Separate arm rests (3, 4) are positioned on both left and right sides of the base section (1). The base section (1) has an indentation (16) for receiving the occiput of a patient's head. The pad (2) has an indentation (115) for receiving the occiput of a patient's head and which is aligned with indentation (16) when pad member (2) is positioned on the head section (11). The apparatus raises the obese patient's head and neck above the patient's chest and positions the patent's head in a stable, extended position to allow easy ventilation and intubation.

Abstract: A walking assist device is capable of operating at an appropriate cycle in view of the motion cycle of a human being to be assisted while at the same time reducing the number of control parameters to be adjusted or set. A second phase oscillator, based on which the phase of the periodic operation of each actuator is controlled, is calculated on the basis of the difference between a first phase oscillator, which indicates a phase of the periodic motion of each thigh relative to the upper body of a human being, and the second phase oscillator, and an intrinsic angular velocity. A current intrinsic angular velocity is set by correcting a previous intrinsic angular velocity by an amount based on a previous difference between the first phase oscillator and the second phase oscillator such that the previous difference approaches a desired difference.

Abstract: A medical crutch having a number of bends in the frame for redistributing the amount of pressure applied to a user's hand, arm, and axilla. The frame has a first jog outwardly sidewards relative to a user's body and a second jog outwardly forward relative to the user's body. The frame may attach an adjustable handle, forearm rest and underarm support, among other attachments. The frame is adapted to fit all average sizes by adjusting the positions of the attachments.

Abstract: The present invention is a mobility device, (also referred to as a “rollator”), which provides a weight bearing architecture and enables the user to maintain an erect body posture and body weight support through the upper arms while enabling the legs to freely move under the user's center of body weight. Upper arm support is enabled through padded forearm rests, or “arm saddles”, which provide an elevated cushion rearward to support and position the user's elbows and transfer the center of the body weight vertically downward and through the rollator frame and thereby falling within its base of support as defined by its four support wheels. The invention's base of support is smaller than conventional rollators, thereby enabling responsive rotational movement by transferring the user's spinal rotation through the aforementioned arm saddles to the rollator frame resulting in a low-radius turn.

Abstract: A personal massager comprises a housing having a front end and a back end. A motor is mounted within the housing, and a crank is configured to move in a circular path within the housing when actuated by the motor. A rocker arm having a first end and a second end is rotatably coupled at a first location to the housing. An armature having a first end and a second end is rotatably coupled at a first location to the crank, and is rotatably coupled at a second location to a second location on the rocker arm. The armature may also be rotatably coupled at a third location to a third location on the rocker arm. A massage head is coupled to the first end of the armature.

Abstract: A sound treatment system includes an audio system for transmitting tones of predetermined frequencies through a plurality of outputs. A sound transmitting device is electrically connectable to one or more of the outputs, and includes a speaker for transmitting the tones received. The speaker is adjacent to crystal which is vibrationally responsive to the tones. A method of using the system includes generating tonal segments of predetermined duration, modulating the frequencies, and compiling these into an audio program. One or more sound transmitting devices are placed on desired locations of the body, and their inputs connected to corresponding outputs of the audio system. The generating step includes compiling selected predetermined frequencies into an audio program to generate the tonal segments, as well as modulating tones of one or more desired frequencies to generate the tonal segments.

Abstract: A device and method coupled to a therapy garment to apply pressure and repetitive compression forces to a body of a person has an air pulsator and a user programmable time, frequency and pressure controller operable to regulate the duration of operation, frequency of the air pulses and a selected air pressure applied to the body of a person.

Abstract: Provided are a gas mist pressure bathing method and a gas mist pressure bathing system that improve the efficiency of absorbing a gas mist from the skin and mucous membranes of a living body. The gas mist pressure bathing method is provided with a first step, a second step and a third step. The first step involves supplying a gas mist for a predetermined time to at least a first cover 51 of a living body cover member 50 having said first cover 51 and a second cover 55 positioned outside of the first cover 51, the inside of said second cover 55 being substantially sealed; covering the skin and mucous membranes of the living body; and forming a space wherein the gas mist supplied by a gas mist generating means 30 is sealed. The second step involves discharging the gas mist from the first cover 51 and/or the second cover 55.

Abstract: A carbon dioxide gas mist pressure bath apparatus for preventing, improving or curing an ischemic disease by contacting a carbon dioxide gas mist to a skin and a mucous membrane of a living organism directly or through a clothing, thereby to improve or promote a circulation of a blood in an ischemic region, includes a carbon dioxide gas mist-enclosing unit; a gas supply unit for supplying a carbon dioxide gas; a carbon dioxide gas mist generating and supplying unit for pulverizing and dissolving the carbon dioxide gas into a liquid, and supplying the carbon dioxide gas mist into the carbon dioxide gas mist-enclosing unit; an exhausting device for exhausting the gas in the carbon dioxide gas mist-enclosing unit to an outside thereof; and a control device for controlling a supplying amount of the carbon dioxide gas mist from the carbon dioxide gas mist generating and supplying unit.

Abstract: A spa chair with a novel pedicure basin is disclosed. The pedicure basin has a main basin and a secondary basin. The main basin is where the feet of the person sitting in the spa chair goes. This main basin is generally filled with water. In one embodiment, the main basin has water overflow protection through a lowered rim, directing the overflow of water to a secondary basin. This method of overflow protection is especially useful where the main basin has a liner blocking the drain hole within the main basin.

Abstract: A pill organizer having a plurality of storage compartments in which pills can be stored. The device includes a housing having recessed areas in which several elongated containers can be removably positioned. The elongated containers are separated into multiple compartments each having a hinged lid. The compartments are arranged in a grid so as to represent the days of the month. The compartments further include numbered indicia on the lid thereof. The housing further includes a digital display thereon for showing the day of the month, and optionally the full date and time. A notepad is provided on the housing for allowing the user to write notes and reminders regarding his or her medication. Thus, the present invention provides a device that allows a user to more easily store and organize his or her medications.

Abstract: A method of diluting concentrated solutions used to treat allergic symptoms is disclosed. The method includes placing a predetermined amount of one of a diluent, a concentrated solution, and a combination thereof into an empty vial of a plurality of vials including an empty maintenance vial, a diluent vial, an intermediate vial and an empty start vial. The method further includes removing an amount of concentrated solution and placing the concentrated solution into an empty maintenance vial, removing an amount of diluent and placing a portion of the diluent from the diluent vial into each of the intermediate vial and the start vial, removing an amount of concentrated solution and placing the concentrated solution from the maintenance vial into the intermediate vial. The method still further includes removing an amount of solution from the intermediate vial and placing the solution from the intermediate vial into the start vial.

Abstract: A beverage container is provided for separately storing a liquid apart form an additive until mixing. The beverage container has a vessel for retaining the liquid and a compartment for retaining the additive. The vessel has an open base at an end and a release valve is connected to another end. A base coupler is connected to the open base. The compartment has a connector at each of an open end and an opposing closed end of the compartment. Connecting the closed end and the open end of the compartment to the base coupler selectively separates and mixes the liquid and the additive, respectively. The beverage container has a closure for sealing the open end of the compartment when the liquid and additive are separated. A method for separating storing and mixing a liquid and additive is also provided. A kit assembly for a beverage container is also provided.

Abstract: A bottle teat made of a soft elastic material, comprising: a hollow suction nipple, a circumferential mounting edge for fixation to the bottle opening of a drinking bottle, a hollow transition zone between the mounting edge and the suction nipple, and two drinking slots extending from the outer side to the inner side of the suction nipple in an end region of the suction nipple, which are aligned in parallel to each other and whose distance from each other decreases from the outer side towards the inner side of the suction nipple.

Abstract: Two-part resin-reinforced cement compositions, kits, and related methods are used for bonding a dental prosthetic appliance to a tooth. A first part includes an amine activator component and a zinc oxide reactive filler, while a second part includes a polymerization initiator (e.g., benzoyl peroxide) and a polymerizable component having a structure including at least one acrylate or methacrylate group at one end and a carboxylic acid group at another end. A temporary cement composition advantageously exhibits reduced compressive and/or bonding strength relative to permanent cement compositions, which provides sufficient strength to facilitate normal use of the teeth while the provisional appliance is in use, while also facilitating easy removal of the provisional appliance for replacement with a permanent appliance at a later time.

Abstract: Curable multicomponent dental material, including a first paste, which contains (i) one or more acid group-free radically polymerizable monomers and (ii) basic filler, and a second paste, which contains (iii) one or more acid group-containing radically polymerizable monomers and (iv) non-basic filler, wherein the multicomponent dental material contains at least one initiator (v) for radical polymerization in at least paste (A) or (B).

Abstract: An aqueous dental glass ionomer composition comprising (a) a reactive particulate glass, and (b) a linear or branched polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the linear or branched polymer comprising acidic groups has a polymer backbone and optionally pendant side chains, (c) optionally dispersed nanoparticles, and (d) optionally a low molecular compound, characterized in that the glass ionomer composition comprises—S.sub.xH groups, wherein x is an integer of from 1 to 6, which crosslink the particulate glass and/or the linear polycarboxylic acid and/or the optional dispersed nanoparticles and/or the optional low molecular compound.

Abstract: The present invention relates to a composition comprising an NF?B-inhibitor and a non-retinoid collagen promoter.

Abstract: An effervescent foamable two-component oral care composition in which a first component contains an acid, and a second component contains an alkaline source such as a carbonate; wherein one or both of the first and second components also contains a surfactant; and, wherein the first and second components are combinable to form an effervescing oral care foam.

Abstract: Cosmetic compositions comprising salicylic acid dimers and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The salicylic acid derivatives are believed to have modulatory activity against one or more biochemical pathways implicated in the appearance of human skin.

Abstract: The compositions and methods of described herein comprise novel ingredients effective to reduce unwanted pigmentation, such as skin discoloration, freckles, age spots, liver spots, sun damage, tans, pigmented acne marks, scars, pigmented birthmarks, hyperpigmentation, post-inflammatory hyperpigmentation, post-injury hyperpigmentation, melasma, cholasma, after-burn scar, nail stain, yellowing of skin, dark circles under eyes, and the like. The composition may include additional ingredients accordingly for a colored cosmetic, moisturizer, cleanser, toner, and the like.

Abstract: Cosmetic compositions comprising substituted carbamoyl heterocyclic analogs and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The substituted carbamoyl heterocyclic analogs are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.

Abstract: The present invention relates to novel compounds and their use as fragrance materials.

Abstract: The affinity of collagen for the skin and its persistence on the skin are improved without destroying the triple helical structure inherent in collagen to thereby improve its ability to retain the moisture of the skin and increase the amount of bound water when such collagen is used as a skin cosmetic. The collagen can thereby exert its moisture retention effect more effectively. A cosmetic base includes an aqueous solution of a liposome that is surface-modified with water-soluble collagen having a triple helical structure.

Abstract: The present invention relates to a hair cosmetic capable of giving good finger combability and manageability with no oily feeling to the hair treated therewith and dried, and to a method for producing the hair cosmetic. The hair cosmetic contains a cationized hydroxypropyl cellulose (A), an oil (B) of which the amount of dissolution in 100 g of water at 20° C. is from 0 to 1 g, and a surfactant (C), wherein the cationized hydroxypropyl cellulose (A) has an anhydroglucose-derived main chain and has a degree of substitution with cationized ethyleneoxy group of from 0.01 to 2.9 and a degree of substitution with propyleneoxy group of from 0.1 to 4.0, and the production method is for producing the hair cosmetic.

Abstract: A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.

Abstract: The present invention is directed to a series of glycerin based polymers that have been designed to have very specific substitution patterns, herein referred to as regiospecific substitution (RSS). The attachment of terminal mono-functional silicone polymers engineered polyesters of glycerin results in heretofore unrecognized products. The unique properties include lower surface tension, better spreadability and a dry skin feel, all of which cannot be attained without the use of a terminal silicone. Incorporation of silicone into the terminal position requires a very specific synthesis regime to establish the sought after regiospecificity.

Abstract: An emulsion is obtained from emulsion polymerization of a mixture of (a) 1-50 wt % of a triorganosiloxysilicic acid and (b) 50-99 wt % of an ethylenically unsaturated monomer in the presence of (c) an emulsion stabilizer which is an anionic surfactant, nonionic surfactant or polyvinyl alcohol. The emulsion is used to formulate a cosmetic composition capable of forming, on drying, a film which has water resistance, oil resistance and toughness and is thus effective for preventing makeup deterioration. The cosmetic composition containing the emulsion is useful as eyeliner, mascara, eyebrow color, liquid foundation or milky lotion.

Abstract: A cosmetic has a polymer (A) having a content of an oxyalkylene unit and/or a glycerin unit of 0.5% by mass or more and under 5.0% by mass; and a polymer (B) having a content of an oxyethylene unit and/or a glycerin unit of 5.0% by mass or more and 20.0% by mass or less, the polymer (A) and the polymer (B) being a crosslinking organopolysiloxane polymer obtained by reacting organohydrogen polysiloxane having two or more hydrogen atoms bonded to a silicon atom in one molecule and polyoxyalkylene and/or polyglycerin having two or more aliphatic unsaturated bonds in one molecule, wherein the mass ratio of the polymer (A) to the polymer (B) is 5:95 to 60:40.

Abstract: Human sebum mimetics and methods for producing human sebum mimetics are provided. In one exemplary embodiment, a human sebum mimetic comprises a wax ester derived from interesterification of a refined botanical triglyceride oil comprising palmitoleic acid and refined jojoba oil, a phytosterol, phytosqualene, and phytosteryl macadamiate. A method for producing a human sebum mimetic comprises mixing refined macadamia oil and refined jojoba oil, interesterifying the macadamia oil and the jojoba oil, adding a phytosterol, adding phytosteryl macadamiate, and adding phytosqualene after interesterification.

Abstract: A composition for the topical application on a mammalian skin comprises one or more Brassica plant extracts selected from the group consisting of: Brassica juncea extract, Brassica oleracea italica extract, Brassica oleracea capitata extract, Brassica oleracea botrytis extract, and Brassica oleracea acephala extract. The composition further comprises one or more selected from the group consisting of: Curcuma longa extract, curcuminoids, tetrahydrocurcuminoids, metabolites of curcuminoids or tetrahydrocurcuminoids, and derivatives of curcuminoids or tetrahydrocurcuminoids. The composition further comprises one or more selected from the group consisting of: Camellia oleifera extract, Camellia sinensis extract, green tea extract and white tea extract; Wasabia japonica extract; Bacopa monnieri extract; Silybum marianum extract; and one or both of Piper nigrum extract or tetrahydropiperine.

Abstract: Described herein are various natural ingredients for skin-related applications. Individual compounds provide beneficial effects for improved collagen production, fibroblast proliferation, antioxidant protection and free radical inhibition. Combinations of these individual compounds exhibit synergistic effects, leading to dramatic improvements in skin moisture levels, wrinkle reduction, and elasticity. Various examples of combined ingredients are provided, which can be applied in methods related to conditioning the skin, and in cosmetic formulations for improved aesthetic appearance.

Abstract: A method for identifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and compositions that include such agents. The method includes providing a test culture of a test agent, a human skin commensal microorganism and a minimal carbon medium. The method provides a time efficient and cost effective way to predict in vivo prebiotic activity of a test agent on skin commensal microorganisms.

Abstract: A therapeutic device and therapeutic method for delivering electrical energy or medicament to a body tissue or organ utilizing ultrasonic vibration to cause a device implanted in the body tissue or organ to be treated to discharge an electrical current or medicament to the target area.

Abstract: The present invention comprises compositions and methods for providing antimicrobial compositions. The antimicrobial compositions comprise gel delivery vehicles comprising stabilized silver, wherein ionic silver is provided to a site for antimicrobial purposes. Methods of making and using such compositions are taught, including application of the silver-containing gel compositions to wounds, burns, abrasions, cuts, surgical incision, sites where skin or organ integrity has been breached, and other sites to supply an antimicrobial environment.

Abstract: A composition prepared for treating animals suffering from parasites which parasites are known to be susceptible to at least one of the avermectins, milbemycins or salicylanilides, comprises for example ivermectin in an amount of from 0.1 to 10%(w/v), a solvent selected from the group consisting of glycerol formal, propylene glycol, polyethylene glycol and combinations thereof, and a salicylanilide such as closantel in a required dosage amount for the animal to be treated, typically about 2.5 mg/kg live weight of the animal to be treated, a polymeric species selected from the group consisting of polyvinylpyrrolidone and polyoxypropylene/polyoxyethylene block copolymers, the said polymeric species improving the bioavailability of closantel to the extend that blood plasma levels of the said compound greater than about 20 ppm over period of treatment are achievable.

Abstract: The present invention relates to compositions and methods for the preparation, stabilization, and/or storage of active agents, particularly therapeutic proteins and polypeptides such as Interleukin-2.

Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.

Abstract: Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing and/or controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).

Abstract: Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.

Abstract: Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.

Abstract: The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a drug. The base is produced by dispersing, in an organic solvent having a solubility parameter of 9.7 or higher, an edible polymer soluble in water and the organic solvent, and particles of one or two or more compounds selected from the group consisting of mono- to hexasaccharide sugars and sugar alcohols thereof which have an average particle size of 0.1 ?m to 60 ?m and are insoluble in an organic solvent. The present invention can therefore provide oral film-form base and preparation which have a rapid dissolution profile in the mouth and sufficient film strength, and provide a reduced sticky sensation attributed to the water-soluble polymer in the mouth and an improved feel when handled with the fingers.

Abstract: The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.

Abstract: The disclosure provides a drug composition formulated for inhalation comprising a conjugate of a surface active agent and a pulmonary active drug. The surface active agent has an affinity for the human alveolar/gas interface and comprises at least a portion of a mammalian lung surfactant of a mimic thereof. The disclosure also provides a method of treating a subject suffering from or at risk of suffering from a lung disease comprising administering to the subject a conjugate comprising a drug for lung treatment and a surface active agent by inhalation in an amount effective to induce a drug effect in the lungs.

Abstract: The present invention aims to provide a matrix-type solid preparation that has high-level release controllability for suppressing drug release in the upper gastrointestinal tract and accelerating drug release in the lower gastrointestinal tract, and that solves of all the above drawbacks caused by combining a plasticizer. The present invention provides a method for producing a matrix-type pharmaceutical solid preparation that contains: (a) a methacrylic acid-based enteric polymer; (b) a sugar and/or a sugar alcohol, and (c) tolvaptan.

Abstract: Taste masked multi-layered particles include an inert core, one or more coating layer(s) comprising a pharmaceutically active ingredient and a binder, an intermediate coating layer (seal coating) free from a low molecular weight water-soluble ionic compound and including a water-soluble pharmaceutical film-forming compound selected from (i) HPMC and PEG or (ii) PVP, and an outer coating layer (final or taste masking coating) free from a low molecular weight water-soluble ionic compound and comprising (i) a poly(meth)acrylate or (ii) a mixture including 60-90% (w/w) EC and 10-40% (w/w) HPMC, where the pharmaceutically active ingredient is water-soluble and includes either at least one basic group and/or a bitter taste. Further disclosed are methods for the production of such particles and pharmaceutical compositions including such particles.

Abstract: A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.

Abstract: There is provided an extended release pharmaceutical composition comprising from about 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also provides an extended release pharmaceutical composition comprising triple combination of from about 30 mg to about 300 mg of levodopa, 10 mg to about 100 mg of carbidopa and 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also relates to process of preparation of such compositions.