Abstract: A medical device is configured to receive at least two physical cardiac electrical signals from a patient's heart via electrodes defining at least two physical sensing vectors. The medical device determines a signal feature for each of a plurality of virtual sensing vectors extending at a plurality of angles relative to one of the at least two physical sensing vectors during a known cardiac rhythm, compares the determined signal features and establishes criteria for confirming a suspected condition in response to the comparing.

Abstract: A method and medical device for determining a cardiac event that includes determining classification factors in response to a sensed cardiac signal, and classifying the cardiac signal as one of a plurality of cardiac events in response to the determined classification factors.

Abstract: The present invention proposes a relaxation state evaluation system and method and a computer program product thereof. The method comprises steps: measuring ECG data of a user; analyzing the ECG data to generate a first, second, third and fourth parameters, wherein the first parameter is the short-scale entropy slope of the user before cardiovascular disease treatment (CVDT); the second parameter is the difference of the post-CVDT and pre-CVDT mean RR intervals; the third parameter is the logarithm of the variance of the pre-CVDT high frequency NN intervals; the fourth parameter is the logarithm of the ratio of the variances of the pre-CVDT low frequency and high frequency NN intervals; working out an evaluation index, which is a function of the abovementioned parameters; and evaluating the relaxation state of the user, wherein the user is determined to be in a relaxation state if the evaluation index is over a threshold.

Abstract: Disclosed is a method and system for determining a cognitive load of a subject from Electroencephalography (EEG) signals. EEG signals are received from EEG channels associated with a left-frontal brain lobe. EEG signals are associated with a subject performing cognitive task. EEG signals are received from a low resolution EEG device. EEG channels comprise four EEG channels associated with the left-frontal brain lobe. EEG signals are preprocessed using a Hilbert-Huang Transform (HHT) filter to remove a noise corresponding to one or more non-cerebral artifacts to generate preprocessed EEG signals. Features comprising Fast Fourier Transform (FFT) based alpha and theta band power are extracted from the preprocessed EEG signals. Feature vector is generated from the features. The feature vector is classified using a Support Vector Machine (SVM) classifier to determine the cognitive load of the subject.

Abstract: Electrode impedances on a body of a subject are measured by connecting a sense electrode, a reference electrode and a return electrode to the body, using the sense electrode to deliver a test current from a current source to the body of the subject, and measuring the potential difference between the sense electrode and the reference electrode. The impedance of the sense electrode on the body is measured in accordance with the measurement of the potential difference between the sense electrode and the reference electrode.

Abstract: The present technology is an automated method for determining whether a patient-specific electrocardiogram (ECG) is either (a) Normal and can be excluded from manual review or (b) Abnormal and included for manual review. In one embodiment, the method comprises comparing a plurality of characteristics of the ECG with predetermined subthreshold levels that are set less than clinically significant levels of abnormality of the characteristics, wherein the characteristics of the ECG are selected from the group including T-Wave inversion, ST-Depression, QT segment duration, delta wave character, anterior S-wave character and ectopic or pre-mature beats. The method continues by selecting the ECG for manual review if the plurality of selected characteristics exceed the predetermined subthreshold levels yet are below the corresponding clinically significant threshold levels of abnormality of the characteristics.

Abstract: The invention relates to a device comprising a number of electrode assemblies (10), which can be applied to the skin surface (4) of an animal or human being and by means of which voltages and currents can be tapped from the skin surface (4), and comprising a flexible, in particular extendable, retaining element (6) formed by a planar or film-like molded part. According to the invention, the electrode assemblies (10) comprise a main body (1) and a number of pin electrodes (2) that protrude from the main body (1) in the same direction, the electrode assemblies (10) are fastened to the retaining element (6), and the main body (1) of the respective electrode assembly (10) is connected to the retaining element (6), wherein the pin electrodes (2) of all electrode assemblies (10) protrude in the same direction.

Abstract: A non-transitory computer readable medium stores instructions that, when executed by at least one processor, cause the at least one processor to perform a method that includes computing a transfer matrix representing a relative influence that each respective electrode location for measuring electrical potentials on a patient's body has on an estimation of electrical potentials for locations on a surface of interest prior to the measuring of electrical potentials at the respective electrode locations and receiving electrical potential measurements measured via a plurality of electrodes at respective electrode locations on the patient's body. The method also includes computing the estimation of electrical potentials for the locations on the surface of interest based at least in part on the received electrical potential measurements and the computed transfer matrix and generating image data representing the estimation of electrical potentials.

Abstract: A wearable patch capable of wireless communications includes an elastic layer, an adhesive layer under the elastic layer, and a shearable electrode layer that includes: a support substrate comprising one or more openings so positioned to allow the shearable electrode layer to be sheared and elongated, and breathable, an upper electrode layer on the support substrate, and a lower electrode layer under the support substrate. The support substrate can include a via that is conductively connected to the upper electrode layer and the lower electrode layer. The lower electrode can be in contact with a user's body and to pick up electric signals from the user's body.

Abstract: Provided are a system and method for analyzing an electroencephalogram (EEG) response to an image stimulus of a media facade which examine, with quantitative data, how emotional reactions of people are affected by image stimuli of different media facades. The system measures EEGs of subjects with respect to stimuli of different media facades and analyzes reaction characteristics, such as activities of respective EEG bands, activities of EEG bands according to brain regions, regional correlations according to the EEG bands, and differences in activities of EEG bands between male and female groups of subjects.

Abstract: Methods and systems process an MRI image to detect cancer. A method includes forming a series of binary threshold intensity images from an MRI image of a patient. Each of the binary threshold intensity images is based on a respective intensity. The binary threshold intensity images are processed to identify one or more bright extremal regions in which image pixels have the same value, and for which corresponding image pixels in the MRI image have a higher intensity than surrounding image pixels in the MRI image. One or more bright maximally stable extremal regions are selected from the identified bright extremal regions based on change in area of one or more respective bright extremal regions for different binary threshold images in the series. At least one of the selected one or more bright maximally stable extremal regions may be identified as potentially cancerous.

Abstract: A device for detecting electric potentials includes a plurality of measuring inputs (9) for connecting to measuring electrodes (11), which can be placed on the body of a patient (3), a plurality of measuring amplifiers (Op1, . . . , OpN), and a potential output (27) for connecting to an additional electrode (31), which can be placed on the body of the patient (3), to which a preset voltage can be applied. A summing unit (17) sends a signal, which is an indicator of the mean value of the signals sent by the measuring amplifiers (Op1, . . . , OpN). A current-measuring device (29) sends a current signal, which is proportional to the current flowing through the potential output. An analyzing unit (35) is connected to receive a potential output voltage signal, the summing unit output (19) signal and the current-measuring device signal. The analyzing unit is configured to generate an impedance signal from the fed signals.

Abstract: Systems and methods for generating MRI images of the lungs and/or airways of a subject using a medical grade gas mixture comprises between about 20-79% inert perfluorinated gas and oxygen gas. The images are generated using acquired 19F magnetic resonance image (MRI) signal data associated with the perfluorinated gas and oxygen mixture.

Abstract: The application relates to a device for the iterative measurement of the circumference of an object, in particular a limb, comprising: a first longitudinal graduated measuring element having a first longitudinal direction, arranged to be placed alongside said object, in particular alongside said limb and defining a slide, a distal strap and a proximal strap each located in a plane substantially perpendicular to said longitudinal direction, and a slider engaging with said slide, linked to a second longitudinal graduated measuring element, said slider having a hole for the slide to pass through and being positioned between said distal strap and said proximal strap.

Abstract: Some embodiments of the invention provide methods and apparatus for controlling any aspect of a virtual environment in a mobile or wearable device, where the user is performing a gait activity such as walking, jogging or running, and the controlling is performed leveraging the gait characteristics of the user. In some embodiments, the gait characteristics include velocity and stride length. In some embodiments, the only sensors utilized to obtain any contextual information are accelerometers.

Abstract: There is provided a fall detection system, comprising a user device comprising one or more sensors for measuring the movements of a user; and the system further comprising a processing unit configured to operate in a first mode in which the processing unit processes the measured movements to determine if the user has fallen and a further mode in which the processing unit processes measured movements obtained during a user-specified time period to determine the risk of the user falling.

Abstract: The present invention extends to methods, systems, and computer program products for providing a matching system for correlating accelerometer data to known movements. Data representing known movements can be obtained and stored in a database such as by processing and storing accelerometer data obtained from one or more accelerometers worn by a user while performing a particular movement. The accelerometer data obtained from a particular movement can be processed to generate a feature set descriptive of the accelerations associated with a particular movement or series of movements.

Abstract: The present invention extends to methods, systems, and computer program products for providing a matching system for correlating accelerometer data to known movements. Data representing known movements can be obtained and stored in a database such as by processing and storing accelerometer data obtained from one or more accelerometers worn by a user while performing a particular movement. The accelerometer data obtained from a particular movement can be processed to generate a feature set descriptive of the accelerations associated with a particular movement or series of movements.

Abstract: Certain embodiments provide a hearing testing probe apparatus. The hearing testing probe apparatus includes a probe tube detachably coupled at a first end to a probe body and extending through a center hole in an eartip to align proximate a face of the eartip at a second end. The probe tube includes a plurality of stimulus lumens for receiving and carrying stimulus from the first end of the probe tube for output at the second end of the probe tube. The probe tube includes one or more microphone lumens for receiving and carrying one or more measured responses from the second end of the probe tube to one or more microphones at the first end of the probe tube.

Abstract: Methods and systems for monitoring or testing the hearing of a user using a portable unit include presenting a plurality of test frequencies for selection by a user and storing data about those frequencies, and the user's response to stimuli presented at those frequencies, and comparing the stored data to previously acquired hearing data. Using mathematical prediction algorithms, changes in baseline hearing values can be used to identify potential hearing issues, especially hearing issues associated with ototoxicity.

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: A blood oxygen graph (200) that specifies blood oxygen level ranges varying over a span of time is displayed within a graphical user interface. Data from at least one physiological sensor is received that includes a current blood oxygen level (230) of a patient and a time point (260) associated with the measurement. Using the received data, the current blood oxygen level for the patient overlaid on the blood oxygen graph at the time point is displayed in the graphical user interface. Related apparatus, systems, techniques, and articles are also described.

Abstract: A device includes a pre-sample reservoir, an actuator mechanism, and a diverter. The pre-sample reservoir can be fluidically coupled to a delivery member to receive and isolate a predetermined volume of bodily-fluid withdrawn from a patient. The actuator mechanism is operably coupled to the pre-sample reservoir such that, when actuated, a negative pressure is formed in the pre-sample reservoir that urges the bodily-fluid to flow into the pre-sample reservoir. The diverter can selectively control fluid flow between the delivery member and the pre-sample reservoir. The diverter includes a flow control mechanism that defines a first fluid flow path and a second fluid flow path. The diverter is movable between a first configuration in which the bodily-fluid flows through the first fluid flow path to the pre-sample reservoir, and a second configuration in which the bodily-fluid flows through the second fluid flow path to a sample reservoir coupled to the diverter.

Abstract: A device for sampling blood comprising a test strip having a planar configuration having a top surface and a bottom surface, said bottom surface having one or more microneedles projecting therefrom and each microneedle having an elongated body having a first end and a second end, said first end forming a tip and said second end forming a base, said base affixed to said bottom surface of said platform.

Abstract: Parametrical analysis of uroflowmetry test results to identify urological disorders particularly to distinguish men who have low urinary tract disorder/benign prostatic hyperplasia from those who have overactive bladder. Primary urine flow dynamic parameters and secondary urine flow dynamic parameters are calculated. Patient's urological disorders can be assessed by comparing the primary and secondary urine flow dynamic parameters with a library or database of comparable data derived from healthy or normal individuals as well as comparable data derived from individuals afflicted with specific urological disorders. A predictive model of lower urinary tract function disorders can be developed from existing reference primary and secondary urine flow dynamic parameters. The model allows for complex analysis and objective disease prediction.

Abstract: The present invention provides an apparatus for sensing a status of testicular torsion and a method thereof, and is related to technical fields of measuring human pulse, heart rate, blood pressure, or blood flow, for sensing the status of a test area in a user. The apparatus comprises a sensor configured for projecting a specific wavelength light source to the test area and receiving a reflected light from the test area, for obtaining a pulse information and an oxygen saturation information on the test area; a comparing unit configured for determining a status of blood flow in the test area and a corresponding status of testicular torsion, according to the pulse information and the oxygen saturation information; and a display unit for displaying the testicular torsion status.

Abstract: An exercise managing method and an exercise managing apparatus are provided. The exercise managing method involves determining, with a processor, a cumulative heart rate (HR) indicating a cumulative sum of HRs of a user, analyzing an exercise performed by the user based on the cumulative HR, and providing a result of the analyzing to the user.

Abstract: A method and an apparatus for recommending a route are provided. The route recommending method includes obtaining user's current body information; obtaining geographic information from a current position to a destination; and determining a recommended route to the destination on the basis of the body information and the geographic information.

Abstract: The illumination apparatus and methods described herein increase the depth of the illumination's tissue penetration, help minimize surface reflections and back-scatter for a non-contact camera based imaging system thus providing increased tissue-structure contrast and more information about the structures beneath the surface.

Abstract: According to some aspects, one or more systems and methods for the diagnosis of a medical condition, such as depression, based on an analysis of sleep information. In some embodiments, the diagnostic system includes at least one recorder for recording sleep information about a patient, and at least one analyzer adapted to analyze the sleep information and determine whether the patient is experiencing the medical condition.

Abstract: Device (1) for controlling the intake of drugs, applicable to a package (50) containing one or more doses of a drug, said device (1) comprising: sensor means (21) adapted to detect the vibrational energy transferred to said package (50), in response of interactions of a user with said package (50) to release one or more doses of said drug; a processor (25) connected to said sensor means (21); wherein said processor (25) is configured to calculate intake information of said drug on the basis of the vibrational energy detected by said sensor means (21); system for signalling the intake of drugs; system (100) for controlling the intake of drugs and drug accessories (10, 20, 30, 40, 40b) comprising such device (1) applicable to drug packages.

Abstract: Systems and methods for health issue detection and treatment include collecting, from at least one wearable user device associated with a first user, user health data at a plurality of different times. Previous user health data retrieved from the at least one wearable user device associated with the first user at a plurality of previous times is analyzed to create a first user health profile that is stored in a database. The current user health data retrieved from the at least one wearable user device associated with the first user at a current time is compared with the first user health profile stored in the database and, in response, a first user health deviation is detected. A first user health treatment is then provided for display on a first user device that is associated with the first user.

Abstract: The present invention provides a combined radiotherapy and MRI system in which an imaging coil is mounted on a mechanical arm. The position of the imaging coil is thus known and in embodiments can be controlled to prevent collisions with the patient and unfavourable interactions between the imaging coil and the radiation beam.

Abstract: The invention relates to an active implantable medical device. The device measures for respiratory activity and for detection of a ventilation rate fall event below a predetermined threshold. The device analyzes in real time the various parameters of the ventilation rate fall event and determines whether they satisfy predefined criteria, so as to allocate or not a priori hypopnea suspicion indicator to the event. An anti-hypopnea therapy is selectively triggered on detection of respiratory collapse, but only in the case of current events indicating a priori hypopnea suspicion. The criteria may include: history of intervals between successive events constituting hypopnea episodes; severity of the current event; conformity of a current event profile with a reference profile; physiological, obstructive or central, origin of the event; patient's current sleep stage; and history of the degree of efficacy of the therapies.

Abstract: A bioinformatics process which provides an improved means to detect TGF-? cellular signaling pathway in a subject, such as a human, based on the expression levels of one or more unique target gene(s) of the TGF-? cellular signaling pathway measured in a sample. The invention includes an apparatus comprising a digital processor configured to perform such a method, a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such a method, and a computer program comprising program code means for causing a digital processing device to perform such a method. Kits are also provided for measuring expression levels of unique sets of TGF-? cellular signaling pathway target genes.

Abstract: The provided is a therapy-progress-level monitoring device and a method thereof, providing information, in real time during a therapy, regarding the depth of extracellular photodynamic therapy.

Abstract: Provided discloses an electronic device for calculating physical energy consumption including a gravity sensing module, a storage module, a processing module, and a touch control display module. The gravity sensing module detects at least one movement of the electronic device for calculating physical energy consumption to generate at least one movement signal. The storage module stores a plural physical training mode and a plural predetermined exercise value. The processing module connects to the gravity sensing module and the storage module, the processing module receives at least one movement signal and generates at least one active value depending on the movement signal, and subtracts at least one active value from the predetermined exercise value corresponding to one of the physical training modes to generate at least one exercising consumption signal. The touch control display module connects to the processing module, and receives and displays at least one exercising consumption signal.

Abstract: An apparatus determining an exercise capability of an individual by obtaining heart rate information of the individual, detecting a characteristic point from the heart rate information, and obtaining information to be used to determine the exercise capability of the individual based on the characteristic point.

Abstract: Methods and structures for detecting a physiologic parameter of a target anatomical environment. The device including a housing with a distal portion first port couplable to a probe and a proximal portion; and a sensing unit, a processing unit, and an output unit carried by the housing, the output unit configured to output a reporting signal based on the determined physiologic parameter value such as pressure; the sensing unit, processing unit, and output unit being disposed substantially between the first port and the proximal portion of the housing.

Abstract: A method and medical device for determining a cardiac episode that includes sensing a cardiac signal, identifying the signal sensed during a predetermined time interval as one of a cardiac event, a non-cardiac event, and an unclassified event, determining a number of identified cardiac events, determining a number of identified unclassified events, and determining whether the cardiac episode is occurring in response to the number of identified cardiac events being greater than a cardiac event count threshold and the number of identified unclassified events being less than an unclassified event count threshold.

Abstract: A mobile healthcare device and method of operating the same are provided. The method includes setting a mode of the mobile healthcare device to a measurement mode, displaying a screen for guiding a user to maintain a predetermined position during the measurement mode, and, in response to a predetermined amount of time passing from a time at which the screen begins to be displayed, obtaining state information of the user based on bio information of the user, the bio information being received from a sensor.

Abstract: A portable audio output apparatus, including an audio output module configured to be in contact with a user's body and to output an audio signal, and a body fat sensor configured to sense a body resistance value of the user through at least four body contact nodes, is provided. At least two of the nodes are placed at outer surface areas of the audio output apparatus that are out of contact with the body if the user wears the audio output apparatus.

Abstract: A headset device includes a headset body, a connection unit to move relative to the headset body, and a sensor unit having a light emitting element and a light receiving element to sense a biosignal, the sensor unit mounted to the connection unit to make contact with a human body. The sensor unit may measure a biosignal of a user, and the headset body and the sensor unit are indirectly connected by the connection unit. Accordingly, the sensor unit may be isolated from movement or vibration received through the headset body.

Abstract: A monitoring system for monitoring physiological parameters of a living being. The monitoring system includes a smart garment, a processing unit and a docking station. The docking station enables quick and easy engagement/disengagement of the processor. The docking station is electrically connected to sensors of the smart garment to thereby provide the sensed data to the processor that is docked thereon. The processor is adapted to obtain some or all of the sensed data via a communication interface such as HDMI. The docking station and the smart garment may be interconnected using complementary conductive snap buttons. The docking station may include at least one through opening formed in its back wall, to thereby enable wired operational communication between the processing unit and a respective additional external sensor. The docking station may include a defibrillator protection device to protect the monitoring system from an electric current or voltage surge.

Abstract: A catheter adapted for greater mapping resolution and location precision has a basket-shaped, high density electrode assembly for large-area mapping, and an integrated distal tip providing an array of ultra-high density microelectrodes for acute focal mapping. The basket-shaped electrode assembly 18 has a plurality of electrode-carrying spines and the distal tip has a nonmetallic, electrically insulating substrate body with indentations in which microelectrodes are positioned in a manner that the outer surface is generally flush with the outer surface of the substrate body to present a generally smooth, atraumatic distal tip profile.

Abstract: A system for monitoring a sitting posture includdes a first pressure sensor for sensing a pressure applied to a chair by the left thigh, a second pressure sensor for sensing a pressure applied to the chair by the right thigh, a third pressure sensor for sensing a pressure applied to the chair by the left buttock, a fourth pressure sensor for sensing a pressure by the right buttock, a fifth pressure sensor for sensing a pressure applied to the chair by the left back, and a sixth pressure sensor for sensing a pressure applied to the chair by the right back; a control unit for converting pressure values sensed by the first pressure sensor, the second pressure sensor, the third pressure sensor, the fourth pressure sensor, the fifth pressure sensor and the sixth pressure sensor; and a monitoring unit for storing and displaying the pressure digital data.

Abstract: A system (10) for detecting and displaying baropostural parameters comprises a platform (11) with a footplate (15) intended to accommodate a person standing on it and provided with sensors for detecting the pressure distribution of the imprint of the two feet on the footplate. An electronic acquisition device (32) is connected to the sensors for digital acquisition of the pressure distribution in order to create a map of the pressure points of the feet on the footplate. Calculation means (33a) are designed to calculate, for each foot and for both feet on the footplate, the geometric centres (52, 53, 54) and the barycentres (55, 56, 57) of the map of the pressures and display means (33b) display on a screen (31) a graphical representation of the imprints of the two feet on the footplate together with the corresponding geometric centres (52, 53, 54) and barycentres (55, 56, 57) calculated by the calculation means.

Abstract: A pulse wave sensor includes: a white LED emitting white light to a human body; a G sensor converting, into a first electrical signal, green light included in light emitted from the white LED and reflected within the human body; an R sensor converting, into a second electrical signal, red light included in the light emitted from the white LED and reflected within the human body; and an arithmetic control unit configured to generate a signal showing a heart rate based on a level difference between the first electrical signal and the second electrical signal. Therefore, a distance between the G sensor and the R sensor does not have to be increased, so that an apparatus can be reduced in size.