Patents Issued in May 12, 2016
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Publication number: 20160129210Abstract: A patient interface of the present invention includes a faceplate including a plurality of headgear attachment elements, a seal member operatively coupled to the faceplate; and an adjustment mechanism coupling the seal member to the faceplate. The adjustment mechanism controls the position of the seal member relative to the faceplate such that the seal member is moveable from a first position to a second position and is maintained in the second position during use of the patient interface after being moved to the second position.Type: ApplicationFiled: November 9, 2015Publication date: May 12, 2016Inventors: JEROME MATULA, JR., JASON P. EATON, PETER CHI FAI HO, JAMES DiPASQUALE, DERRICK ANDREWS, EUGENE N. SCARBERRY, STEVEN C. STEGMAN
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Publication number: 20160129211Abstract: A tracheal tube assembly includes an outer cannula configured to be positioned in a patient airway and an inner cannula configured to be disposed inside the outer cannula. The tracheal tube assembly further includes a flange member secured about the outer cannula, and an outer cannula connector coupled to a proximal end of the outer cannula. The outer cannula connector includes a compressible portion may be compressed while inserting or removing the inner cannula.Type: ApplicationFiled: January 19, 2016Publication date: May 12, 2016Inventors: Martin J. Bruggemann, James M. Ryan, Declan Kiernan, Alan Finneran, Seamus P. Maguire
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Publication number: 20160129212Abstract: A humidifier assembly (100, 100-1) includes a reservoir (120), an inlet structure (112, 112-1) leading into the reservoir and an outlet structure (114, 114-1) leading out of the reservoir, and a conduit element (130, 130-1) having a first end (131, 131-1), a body portion (132, 132-1), and a second end (133, 133-1). The first end is fluidly coupled to at least one of the inlet structure and the outlet structure The humidifier assembly additionally includes a float assembly (140, 140-1) coupled to the second end of the conduit element. The float assembly is structured to float on water held by the reservoir. The float assembly has a number of apertures (153, 153-1) structured to be in fluid communication with the outlet structure.Type: ApplicationFiled: June 30, 2014Publication date: May 12, 2016Inventors: Mark William DIMATTEO, Mark Wayne BARCLAY, John Raymond PUJOL
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Publication number: 20160129213Abstract: The present invention provides a device (1) for assisting a cough comprising a hosing (3), a chamber (5) formed in the housing, a mouthpiece (7) communicating with the chamber and exposed out of the housing, and an electromagnetic valve (9) assembly for opening or closing the chamber at a pre-set frequency. The device for assisting a cough according to the present invention may produce a high cough pressure and thus form a strong cough airflow to loose and cough the lung mucus out of the airways, and may prevent the collapse of the patient's airway caused by the rapid release of the cough pressure.Type: ApplicationFiled: June 9, 2014Publication date: May 12, 2016Inventors: XINLI ZHU, WEI ZHOU, JR., HUIMIN CHEN, FENG CHEN, YANG LI
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Publication number: 20160129214Abstract: An elbow assembly includes an elbow with an opening in a sidewall of the elbow. An anti-asphyxia valve (AAV) assembly is provided to the elbow. The opening in the sidewall of the elbow is configured to receive at least a portion of the AAV assembly. The elbow assembly further includes a support member with an atmospheric port. The support member is configured to be secured to a portion of the elbow and cover the opening. The AAV assembly is adapted to be secured to the elbow by the support member. In addition, the support member is configured so that an outer surface of the support member is substantially flush with an outer surface of the elbow when the support member is secured to the portion of the elbow.Type: ApplicationFiled: January 20, 2016Publication date: May 12, 2016Inventors: Muditha Pradeep DANTANARAYANA, Saad NASR
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Publication number: 20160129215Abstract: A method of conditioning a living body of a patient to associate the unconditioned stimulus (US) of decreased sympathetic nerve activity SNA) with the conditioned stimulus (CS) of a representation of an offending agent to cease or reduce defensive reactions or symptoms. The US involves non-invasive, transcutaneous sensory stimulation of the sympathetic ganglia, which is paired with the CS of digital audio representations of offending substances to modify pathologically conditioned. reflexes of various systems involved. in a reaction. In addition, a patient's allergies or sensitivities are treated by using digital representations, preferably provided via a computer, to represent the actual substances in order to engage the multimodal functioning of the brain. Sensory stimulation is used in conjunction with the digital audio signals to condition the body to respond more appropriately to the substance.Type: ApplicationFiled: January 14, 2016Publication date: May 12, 2016Inventor: Dawn Nowlin
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Publication number: 20160129216Abstract: A circulatory water flow sensory system having a water nozzle attached to a basin. A pump sends water from the water reservoir through the nozzle and into the basin. The water then drains from the basin into the water reservoir. The basin is shaped in such a way to allow easy and safe access to the flowing water for children, especially those with developmental disorders such as autism.Type: ApplicationFiled: November 7, 2014Publication date: May 12, 2016Inventors: Louis O. Leazenbee, William B. Brimer
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Publication number: 20160129217Abstract: A hypnotic system includes a physiological parameter detection device, an audio information comparison device, a communication device and an audio device. The physiological parameter detection device detects the physiological parameter of a user for generating a physiological parameter signal. The audio information comparison device receives the physiological parameter signal, locates a respective audio information from an internal audio-comparing table, and then generates a corresponding audio signal for transmitting to the communication device. The audio device receives the audio signal forwarded by the communication device and then plays the corresponding audio information matching user's physiological parameter so as to serve a hypnotic purpose to the user.Type: ApplicationFiled: April 2, 2015Publication date: May 12, 2016Inventor: Feng-Wei HSU
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Publication number: 20160129218Abstract: A display control method for controlling display of a display panel, the display control method including: obtaining an image by photographing a viewer; determining whether the viewer is sleepy based on the image; controlling a display mode of the display panel based on whether the viewer is sleepy; and generating an output signal for displaying an image on the display panel based on the display mode, wherein the display panel includes a first blue pixel emitting a first blue light and a second blue pixel emitting a second blue light having a different wavelength from the first blue light, and the display mode is classified based on which of the first and second blue pixels are used.Type: ApplicationFiled: May 13, 2015Publication date: May 12, 2016Inventors: Rangkyun Mok, Jongin Baek, Wonsang Park, Yijoon Ahn, Byeonghee Won
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Publication number: 20160129219Abstract: A catheter assembly is disclosed, comprising a catheter, such as a urinary catheter, which at least a partly is provided with a hydrophilic coating. The catheter assembly further comprises a wetting fluid. The receptacle is in direct contact with the hydrophilic coating of the catheter over essentially the entire length of the part of the catheter being provided with the hydrophilic coating. This may e.g. be achieved by using a shrink wrap material. In order to accomplish adequate wetting, channels or the like may be provided on the inner surface of the receptacle or the outer surface of the catheter.Type: ApplicationFiled: August 28, 2014Publication date: May 12, 2016Inventors: Evelina GUSTAVSSON, Jan UTAS
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Publication number: 20160129220Abstract: Embodiments relate to a system for providing a first fluid and a second fluid. The system includes a catheter hub, a flexible cover, and a catheter. The flexible cover is configured to attach to the catheter hub and provide a seal therewith. The catheter is configured to be at least partially arranged within the catheter hub and the flexible cover and pass through the seal. The catheter includes a primary lumen and a secondary lumen, wherein the primary lumen is configured to provide the first fluid at a distal end of the catheter, and the secondary lumen is configured to provide the second fluid at each of a plurality of apertures arranged on an outer radial wall of the catheter.Type: ApplicationFiled: November 10, 2015Publication date: May 12, 2016Inventors: Bharathi Dasan Jagadeesan, Sean Lester Moen
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Publication number: 20160129221Abstract: A delivery catheter includes a soft, atraumatic distal tip. The distal tip is configured to transition from a folded configuration to an unfolded configuration during delivery of a medical device. A wall thickness of the distal tip may be increased such that the distal tip is biased to remain in the unfolded configuration after delivery. Additionally, the increased wall thickness in a selected region of the distal tip may cause the distal tip to resist and/or prevent collapse of the distal tip during retrieval and/or repositioning of the medical device when the medical device comes into contact with a distal end of the catheter. The distal edge of the distal tip may be rounded so as to prevent the distal tip from damaging tissue during advancement of the catheter to a target location within a patient's body.Type: ApplicationFiled: November 3, 2015Publication date: May 12, 2016Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: PATRICK A. HAVERKOST, JOEL N. GROFF, MARTIN R. WILLARD, ANTHONY F. TASSONI, JR.
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Publication number: 20160129222Abstract: A catheter assembly is disclosed, comprising a proximal catheter assembly portion and a distal catheter assembly portion. The proximal catheter assembly portion includes a bifurcating hub that defines at least one fluid passageway. The distal catheter assembly portion includes a catheter tube that defines at least one lumen and includes a polymeric material. A cannula assembly is also disclosed and includes at least one cannula that is operably connected with the fluid passageway of the birfurcating hub. The cannula is further configured to operably connect with the lumen of the catheter tube so as to provide fluid communication between the proximal and distal catheter assembly portions when the two portions are connected. A polymeric coating is included with the cannula and the catheter tube, and is configured to provide a seal between the cannula and the catheter tube when the proximal and distal catheter assembly portions are connected together.Type: ApplicationFiled: November 6, 2015Publication date: May 12, 2016Inventor: German Loesener
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Publication number: 20160129223Abstract: An elongate medical device may comprise an elongate tubular body, an electrode, and a trace. The elongate tubular body may comprise a distal end portion and a proximal end portion, the body defining a longitudinal axis. The electrode may comprise electrically-conductive ink extending circumferentially about a portion of the distal end portion. The trace may comprise electrically-conductive ink, electrically coupled with the electrode, extending proximally from the electrode.Type: ApplicationFiled: October 9, 2015Publication date: May 12, 2016Inventor: Mark B. Kirschenman
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Publication number: 20160129224Abstract: A catheter having an internal advancing mechanism that can advance stiffening wires or other devices, has a catheter with a catheter body, a tip section distal the catheter body, a device extending through at least the catheter body, and a control handle proximal the catheter body, where the control handle has an advancing mechanism with a threaded member, an adjustment member, and a guided member to which the device is connected, and the advancing mechanism is configured to advance and retract the device along the catheter body as controlled by a user. Each of the threaded member and the adjustment member has a generally cylindrical configuration. The threaded member has an outer surface configured with a helical guide channel. The adjustment member is configured to guide the guided member to move within the helical guide channel to advance and retract the device. The adjustment member can be rotatable over the threaded member by the user to control advancement and retraction of the device.Type: ApplicationFiled: December 28, 2015Publication date: May 12, 2016Inventors: Keshava Datta, Jeffrey William Schultz
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Publication number: 20160129225Abstract: A needle cover including a cover main body including a needle introduction part and a needle introduction part. An opening is formed on a bottom side of the needle introduction part, and the needle protection part includes first and second needle protection parts on respective top and bottom sides. An opening is formed between the bottom side of the first needle protection part and the top side of the second needle protection part, and the first needle protection part and the second needle protection part are connected on the base side by a needle protection part connection unit and include a terminal opening on the terminal side. On the base side, a wing-fixing unit is formed on the first side and the second of the second needle protection part, and a locking part of the wing-fixing unit is formed on the terminal side.Type: ApplicationFiled: July 29, 2013Publication date: May 12, 2016Applicant: KAWASUMI LABORATORIES, INC.Inventor: Masatoshi WATANABE
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Publication number: 20160129226Abstract: An example of recovery catheter assembly comprises an actuator element and a mechanically radially expandable and contractible recovery device operably connected to the actuator element. The recovery device has proximal and distal blocking portions and a central portion therebetween. The recovery device is at least partially placeable in a first, radially collapsed configuration and in a second, radially expanded configuration by manipulation of the actuator element. When in the second, radially expanded configuration, the proximal and distal blocking portions have radial dimensions greater than the radial dimension of the central portion thereby at least partially defining a collection chamber at the central portion.Type: ApplicationFiled: January 14, 2016Publication date: May 12, 2016Applicant: NFUSION VASCULAR SYSTEMS, LLCInventors: Richard Eustis Fulton, III, Richard Lotti
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Publication number: 20160129227Abstract: Balloon catheter and methods for making and using balloon catheters are disclosed. An example balloon catheter may include a proximal shaft. A midshaft may be attached to the proximal shaft. The midshaft may have an outer wall. A distal shaft may be attached to the midshaft. A balloon may be coupled to the distal shaft. An inflation lumen may be defined that extends from the proximal shaft, through the midshaft, and into the distal shaft. The inflation lumen may be in fluid communication with the balloon. A core wire may be disposed within the inflation lumen and may be attached to the midshaft.Type: ApplicationFiled: January 19, 2016Publication date: May 12, 2016Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Charles Rundquist, Eric Petersen, Jeffry Johnson, Roger W. McGowan, Chuanjing Xu, Adam D. Grovender
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Publication number: 20160129228Abstract: Embodiments are disclosed for an applicator used for inserting flowable pharmaceutical preparations into a body cavity, an adapter for connecting a jar to a cavity dispenser, a jar dispenser with a nozzle for automated transferring and dispensing of flowable pharmaceutical compositions, and a metered dial-dispenser configured to connect to a cavity dispenser for humans and animals.Type: ApplicationFiled: January 17, 2016Publication date: May 12, 2016Inventor: Ramiro M. Perez
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Publication number: 20160129229Abstract: An apparatus worn on the finger that can prevent cracked skin. In order to do so, the apparatus consists of a finger cover, an attachment mechanism, and a quantity of lotion. The finger is inserted into the finger cover through an open end. Next, the finger cover is secured with an attachment mechanism. When secured, the finger will be in contact with the quantity of lotion placed at a closed end of the finger cover. The finger cover is made of transparent plastic. As a result of being transparent, the finger cover has low visibility when worn. The apparatus can be worn when engaging in daily activities since the plastic is lightweight and durable. Since the finger cover is a loose fitting finger cover, the user can wear the apparatus comfortably.Type: ApplicationFiled: November 11, 2014Publication date: May 12, 2016Inventor: Marshall J Pettygrove
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Publication number: 20160129230Abstract: A method of packaging and applying toxic anti-neoplastic pharmaceutical agents for the prevention and treatment of premalignant and malignant lesions of the skin is described. The packaging of liquid formulations containing these toxic anti-neoplastic agents in plastic or glass bottles with control-flow applicators and caps enables patients to apply such formulations to affected areas of skin without having to have physical contact on the part of their hands with the medicaments.Type: ApplicationFiled: January 5, 2016Publication date: May 12, 2016Inventor: Joel E. Bernstein
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Publication number: 20160129231Abstract: A device for scar management includes an applicator head including a recess having a rotating means therein, a reservoir containing a silicone composition fluidly connected to the applicator head, and a metering valve fluidly connected to the reservoir. The composition has viscosity of 3,000 to 8,000 cps, and consists of a mixture of cyclopentasiloxane, dimethiconol, dimethicone, and dimethicone/vinyl dimethicone crosspolymer. A metered dose of the silicone composition is delivered from the reservoir to the applicator head upon the application of external pressure to the metering valve. The invention also relates to a method for scar management using such device by identifying a target skin area having a wound or scar, contacting the outward surface of the applicator head to the target skin area, massaging the rotating means of the applicator head on the target skin area, and applying the silicone composition to the target skin area via the rotating means.Type: ApplicationFiled: January 15, 2016Publication date: May 12, 2016Inventor: Jessica Rowen
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Publication number: 20160129232Abstract: Out-of-plane microneedle manufacturing process comprising the simultaneous creation of a network of microneedles and the creation of a polygonal shaped hat (2) above each microneedle (1) under formation, said process comprising the following steps: providing bridges (3) between the hats (3), maintaining the bridges (3) during the remaining microneedle manufacturing steps, removing the bridges (3), together with the hats (2), when the microneedles (1) are formed.Type: ApplicationFiled: January 6, 2016Publication date: May 12, 2016Inventors: Astrid Cachemaille, François Cannehan
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Publication number: 20160129233Abstract: The present invention relates to an improved method for accelerating restoration of blood flow in treatment of an acutely thrombosed coronary artery by employing real time transthoracic 3D ultrasonic volume imaging at or near the base of the heart, and/or proximate the basal aspect of the associated left ventricular regional wall motion abnormality. Ultrasonic pulses provided by 3D imaging uniquely and necessarily deliver ultrasound to a broad target volume to stimulate the coronary arteries (which are difficult to image with ultrasound, and comprise tortious three dimensional structures), in view to providing an agitative and clot disruptive effect to a hidden, culprit, thrombosed, coronary vessel. In the preferred embodiment an intravenous microbubble solution is concurrently administered with 3D ultrasound which creates a dramatic synergy in disrupting the culprit thrombosis.Type: ApplicationFiled: November 17, 2015Publication date: May 12, 2016Inventor: Andrew Kenneth Hoffmann
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Publication number: 20160129234Abstract: A connecting element for connecting two hollow bodies through which a fluid can flow comprises a first connecting part which can be brought into fluid-tight flow connection with a first hollow body through which a fluid can flow, a sealing element which is arranged at least partially in an inner area of the first connecting part and a locking element which is arranged on an outside of the first connecting part. The locking element can be transferred from an unlocked position into a locked position, wherein the locking element in the locked position acts upon the sealing element in such a way that an inside diameter of the sealing element is smaller than when the locking element is in the unlocked position.Type: ApplicationFiled: June 12, 2014Publication date: May 12, 2016Inventors: Olaf LIEBE, Fabian LANGEN, Nils GELBERT
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Publication number: 20160129235Abstract: An injection port assembly including a body having first and second mating structures configured to mate with a first connector for a first fluid pathway and a second connector on a device, respectively. A resilient barrier substantially contained within the body and compressible from a first position in which fluid flow between the first and second connectors is blocked to a more compressed second position in which fluid flow between the first and second connectors is permitted. A hollow cannula can be coupled with the first mating structure and disposed within the resilient barrier, the hollow cannula having a distal end configured to extend through the resilient barrier when the resilient barrier is in the second position, the distal end having lateral slots. The resilient barrier can have first and second annular sealing rings positioned above and below the lateral slots respectively.Type: ApplicationFiled: November 12, 2015Publication date: May 12, 2016Inventor: Dana Wm. Ryan
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Publication number: 20160129236Abstract: A connecting device (1) for connecting therebetween the respective ends of two ducts prevents that the inside portion of the ducts comes in contact with the atmosphere and with polluting agents before the complete connection thereof by keeping the connection procedure simple to be performed and it comprises two connecting members (2, 4) provided with tubular ends (12, 27) and respective concentric and coaxial tubular casings (17, 32), which penetrate by breaking in sequence respective breakable barriers (20, 40) arranged inside said connection members (2, 4), wherein at lest one of said first and second connecting member (2, 4) comprises a sliding guide comprising at least a groove formed on a surface of an outer cylindrical casing (6) of a connecting member (2), apt to cooperate with a corresponding rib or with one or more teeth (9) implemented at an inner surface of an outer cylindrical casing (8) of the other connecting member (4).Type: ApplicationFiled: May 27, 2014Publication date: May 12, 2016Applicant: GLOMERIA THERAPEUTICS S.r.l.Inventors: Fabio ARRIZZA, Arduino ARDUINI
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Publication number: 20160129237Abstract: An apparatus for delivering therapeutic electrostimulation across a tissue surface includes a current source, a low current component adapted to contact the tissue surface, a first electrode assembly electrically connected to the current source and supported by the low current component, a second electrode assembly electrically connected to the current source and supported by the low current component and a conductive fluid supported by the low current component for facilitating a flow of electric current across the tissue surface. At least one of the first and second electrodes assemblies includes at least one of a magnetic electrode, a high current component and a non-current component.Type: ApplicationFiled: November 9, 2015Publication date: May 12, 2016Inventors: Marom Bikson, Abhishek Datta, Niranjan Khadka
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Publication number: 20160129238Abstract: A method for optimum preparation and placement of transcranial electrodes is described. The method consists of application of liquid silver paint to standard monitoring electrodes and placement of bilateral electrodes over the pterions, the thinnest areas of the skull. This method minimizes the impedance between electrodes facilitating low power stimulation of the brain as measured by the phosphene threshold that has been redefined in this invention. The locations of the pterions vary between racial groups, but in most cases the pterions overlie the anterior temporal lobes. The anterior temporal lobe is contiguous with the amydala and hippocampus and stimulation of these limbic system structures has been known to produce fear, along with other altered states of consciousness. Low power square wave stimulation via these electrodes produces phosphenes at frequencies closely approximating the Schumann resonance frequency and its harmonics and theta, alpha, beta and gamma EEG frequencies of the brain.Type: ApplicationFiled: January 14, 2016Publication date: May 12, 2016Inventor: Joel Steven Goldberg
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Publication number: 20160129239Abstract: In some examples, a system includes an implantable medical device configured for implantation in a chamber of the heart, an extension attached to the implantable medical device, the extension comprising a housing comprising at least one electrode, the housing defining a hole, and a tether comprising a first tether portion and a second tether portion and configured to be threaded through the hole. When the tether is threaded through the hole, the first tether portion and the second tether portion are on opposite sides of the hole. The tether may be used to implant the extension in a different chamber of the heart of the patient than the implantable medical device.Type: ApplicationFiled: November 11, 2014Publication date: May 12, 2016Inventor: Kenneth M. Anderson
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Publication number: 20160129240Abstract: According to an embodiment, an electrode array for a transmodiolar implant is disclosed. The implant includes a substrate, a conductive metal located at a plurality of discrete portions on the substrate; and a single layer of insulation material over the conductive metal and the substrate. The single layer of insulation material includes a plurality of apertures that expose the conductive metal, the exposed conductive metal forming a plurality of electrodes, the electrode array having a Young's modulus of at least 100 GPa.Type: ApplicationFiled: November 6, 2015Publication date: May 12, 2016Applicant: Oticon Medical A/SInventors: Guillaume TOURREL, Dan GNANSIA, Nicolas VEAU
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Publication number: 20160129241Abstract: Disclosed is a carbon material for a neurostimulation electrode. The carbon material is composed of a carbon fiber. The carbon fiber has a thickness of 1 to 1000 ?m, a linear density of 0.01 to 5.00 g/cm, and an aspect ratio of 100 to 1,000,000. Particularly, the carbon fiber material can be obtained by dry spinning carbon nanotubes, followed by liquid-based densification. The carbon material can be used in the fields of deep brain stimulation, spinal cord stimulation, etc. Also disclosed are an electrode assembly and a neurostimulation device, each including the carbon material.Type: ApplicationFiled: June 3, 2014Publication date: May 12, 2016Inventors: Seong Woo RYU, Hae Shin LEE, Moon Sue LEE, Sun Ha PAEK, Mi Young KOH
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Publication number: 20160129242Abstract: A segmented-contact set of a lead includes segmented contacts extending around less than an entire circumference of the lead and not in electrical contact with one another. The segmented-contact set includes first and second segmented contacts that each include a stimulation portion and a retention member. The stimulation portion has a stimulation surface exposed along an outer surface of the lead. The retention member is coupled to the stimulation portion. The stimulation portion and the retention member collectively form a loop of material that extends around a center transverse axis of the lead beneath the outer surface. A first insulating member is disposed between the stimulation portion of the first segmented contact and the retention member of the second segmented contact. A second insulating member is disposed between the stimulation portion of the second segmented contact and the retention member of the first segmented contact.Type: ApplicationFiled: November 6, 2015Publication date: May 12, 2016Inventor: Zdzislaw Bernard Malinowski
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Publication number: 20160129243Abstract: Various system embodiments comprise a lead having a distal end and a proximal end. The distal end includes a plurality of electrodes. The lead is configured to be fed into a dorsal epidural space of a human to a desired region of a spinal column and to be fed laterally to at least partially encircle a spinal cord in the desired region to place at least one stimulation electrode in position to stimulate a dorsal nerve root and at least another stimulation electrode in position to stimulate a ventral nerve root. The desired region may include cervical vertebrae, thoracic vertebrae, or lumbar vertebrae. Some embodiments stimulate the spinal cord in the T1-T5 region.Type: ApplicationFiled: January 7, 2016Publication date: May 12, 2016Inventors: Weiying Zhao, Stephen B. Ruble, Allan C. Shuros, Jason J. Hamann
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Publication number: 20160129244Abstract: A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen or lumen and to provide feedback to lead implanters.Type: ApplicationFiled: November 6, 2015Publication date: May 12, 2016Inventor: Randy W. Westlund
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APPARATUS AND METHOD FOR DETERMINING THE RELATIVE POSITION AND ORIENTATION OF NEUROSTIMULATION LEADS
Publication number: 20160129245Abstract: A method for determining whether the relative position of electrodes used by a neurostimulation system has changed within a patient comprises determining the amplitude of a field potential at each of at least one of the electrodes, determining if a change in each of the determined electric field amplitudes has occurred, and analyzing the change in each of the determined electric field amplitudes to determine whether a change in the relative position of the electrodes has occurred. Another method comprises measuring a first monopolar impedance between a first electrode and a reference electrode, measuring a second monopolar impedance between second electrode and the reference electrode, measuring a bipolar impedance between the first and second electrodes, and estimating an amplitude of a field potential at the second electrode based on the first and second monopolar impedances and the bipolar impedance.Type: ApplicationFiled: November 5, 2015Publication date: May 12, 2016Inventors: Kerry Bradley, James R. Thacker, Michael A. Moffitt -
Publication number: 20160129246Abstract: The present invention relates to improved methods for transfecting one or more cells within a target region with an agent by electroporation. The method comprises exposing one or more cells to the agent and to a close electric field created between an anode or anode array and a cathode or cathode array in the target region for sufficient time to allow at least some of the agent to enter said one or more cells.Type: ApplicationFiled: June 23, 2014Publication date: May 12, 2016Inventors: Gary David Housley, Matthias Klugmann, Jeremy Pinyon
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Publication number: 20160129247Abstract: A method, electrical tissue stimulation system, and programmer for providing therapy to a patient are provided. Electrodes are placed adjacent tissue (e.g., spinal cord tissue) of the patient, electrical stimulation energy is delivered from the electrodes to the tissue in accordance with a defined waveform, and a pulse shape of the defined waveform is modified, thereby changing the characteristics of the electrical stimulation energy delivered from the electrode(s) to the tissue. The pulse shape may be modified by selecting one of a plurality of different pulse shape types or by adjusting a time constant of the pulse shape.Type: ApplicationFiled: January 18, 2016Publication date: May 12, 2016Inventors: Dongchul Lee, Michael A. Moffitt, Christopher Ewan Gillespie, Kerry Bradley
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Publication number: 20160129248Abstract: A topical nerve stimulator patch and system are provided comprising a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.Type: ApplicationFiled: May 30, 2014Publication date: May 12, 2016Inventors: Graham H. CREASEY, Hoo-Min TOONG
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Publication number: 20160129249Abstract: An apparatus for more accurately stimulating a living body comprises: a stimulation unit configured to apply a bio-stimulation signal in vicinity to a living body, the bio-stimulation signal being composed of pieces of time-series data having a specific frequency; and a control unit configured to derive bio-stimulation information required to achieve targeted bio-information using time space data indicative of bio-responses interacting at a plurality of different positions in response to the bio-stimulation signal, and derive a relation between the bio-stimulation signal and the bio-responses, and control the stimulation unit to apply the bio-stimulation signal in response to the derived bio-stimulation information. The relation is configured to set the bio-stimulation information as variables in an X matrix (m, t), set the bio-response information as variables in a Y matrix (n, t), and derive an A matrix (n, m) satisfying Y=AX.Type: ApplicationFiled: January 18, 2016Publication date: May 12, 2016Inventors: Kyongsik YUN, Yongwook CHAE, Kiwon LEE
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Publication number: 20160129250Abstract: A stimulation therapy device provides an electrical stimulation therapy to branches of the tibial nerve of a patient. The device comprises a support member configured to be worn around the ankle or foot of the patient, first and second pairs of electrodes attached to the support member, and a stimulation circuit attached to the support member. The stimulation circuit is configured to deliver electrical stimulation pulses through the first and second pairs of electrodes.Type: ApplicationFiled: January 15, 2016Publication date: May 12, 2016Inventors: David J. Yonce, John Jason Buysman, Richard A. Lundeen, Jeffrey John Childs
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Publication number: 20160129251Abstract: A computer-implemented method for sharing information related to a noninvasive electrical brain stimulation “NIEBS” treatment, comprising: providing a NIEBS treatment to a user via a NIEBS generator, said NIEBS treatment having variables; receiving adjustments to the variables of said NIEBS treatment via user input; and creating a NIEBS Control Profile based on said received adjustments.Type: ApplicationFiled: June 9, 2014Publication date: May 12, 2016Applicant: Brainique AGInventors: Raymond Watt, Jaen Frederik Labuschagne, Michael J. Slater
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Publication number: 20160129252Abstract: A method for providing noninvasive electrical brain stimulation “NIEBS” is provided, the method comprising: receiving a signal at a power converter wherein the signal is an audio signal; converting power from said audio signal to a form suitable for NIEBS; generating a NIEBS signal using said power converted from said audio signal; and applying NIEBS based on said able NIEBS signal to a user via electrodes.Type: ApplicationFiled: June 9, 2014Publication date: May 12, 2016Applicant: Brainique AGInventors: Raymond Watt, Jaen Frederik Labuschagne, John Sandhu
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Publication number: 20160129253Abstract: A computer-implemented method is proposed for providing noninvasive electrical stimulation to stimulate the brain, the method comprising receiving a two channel audio output at a splitter, splitting each of the two signals into a first portion and a second portion, passing said first portion to at least two speakers for playing audio, converting said second portion at a power converter (101) to a form suitable for noninvasive electrical stimulation, generating a signal for noninvasive electrical stimulation based on said second portion and applying noninvasive electrical stimulation to a user based on said signal for noninvasive electrical stimulation via electrodes (103) associated with said two speakers.Type: ApplicationFiled: June 9, 2014Publication date: May 12, 2016Applicant: Brainique AGInventors: Raymond Watt, Jaen Frederik Labuschagne, John Sandhu
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Publication number: 20160129254Abstract: The present disclosure relates to methods, devices and systems used for the treatment of mood, anxiety, post traumatic stress disorder, and cognitive and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.Type: ApplicationFiled: January 19, 2016Publication date: May 12, 2016Inventors: Christopher DeGiorgio, Ian A. Cook, Alejandro Covalin, Patrick R. Miller, Lara Schrader
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Publication number: 20160129255Abstract: A cardiac rhythm management system selects one of multiple electrodes associated with a particular heart chamber based on a relative timing between detection of a depolarization fiducial point at the multiple electrodes, or based on a delay between detection of a depolarization fiducial point at the multiple electrodes and detection of a reference depolarization fiducial point at another electrode associated with the same or a different heart chamber. Subsequent contraction-evoking stimulation therapy is delivered from the selected electrode.Type: ApplicationFiled: January 18, 2016Publication date: May 12, 2016Inventors: Jiang Ding, Julio C. Spinelli, Andrew P. Kramer
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Publication number: 20160129256Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level until a target T-wave alternans change from a baseline T-wave alternans is achieved.Type: ApplicationFiled: November 11, 2015Publication date: May 12, 2016Inventors: Imad Libbus, Bruce H. KenKnight
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Publication number: 20160129257Abstract: A neurostimulation system provides for capture verification and stimulation intensity adjustment to ensure effectiveness of vagus nerve stimulation in modulating one or more target functions in a patient. In various embodiments, stimulation is applied to the vagus nerve, and evoked responses are detected to verify that the stimulation captures the vagus nerve and to adjust one or more stimulation parameters that control the stimulation intensity.Type: ApplicationFiled: January 19, 2016Publication date: May 12, 2016Inventors: Juan Gabriel Hincapie Ordonez, David J. Ternes, Jason J. Hamann, Stephen B. Ruble
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Publication number: 20160129258Abstract: Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.Type: ApplicationFiled: July 10, 2015Publication date: May 12, 2016Inventors: Warren M. Grill, Amorn Wongsarnpigoon
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Publication number: 20160129259Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level. Between titration sessions one or more parameters, such as, for example, an acclimation interval, may be adjusted based on the patient's response to the stimulation. This personalized titration process can minimize the amount of time required to complete titration so as to begin delivery of the stimulation at therapeutically desirable levels.Type: ApplicationFiled: December 8, 2014Publication date: May 12, 2016Inventors: Imad Libbus, Bruce H. KenKnight, Badri Amurthur, Scott R. Stubbs