Abstract: A method of treating cardiovascular disease in a medical patient is provided. The method includes the steps of generating a sensor signal indicative of a fluid pressure within the left atrium of the patient's heart, and delivering an electrical stimulus to a location in the heart. The electrical stimulus is delivered based at least in part on the sensor signal. The method also includes the steps of generating a processor output indicative of a treatment to a signaling device. The processor output is based at least in part on the sensor signal. At least two treatment signals are provided to the medical patient. The treatment signals are distinguishable from one another by the patient, and are indicative of a therapeutic treatment. The treatment signals are based at least in part on the processor output.

Abstract: In some examples, a leadless pacing device (LPD) is configured to switch from a sensing without pacing mode to ventricular pacing mode in response to determining that no intrinsic ventricular activity was detected within a ventricular event detection window for at least one cardiac cycle, which may be referred to as loss of conduction. The ventricular pacing mode may be selected based on whether atrial oversensing is detected in combination with the loss of conduction. In some examples, an atrio-ventricular synchronous pacing mode is selected in response to detecting loss of conduction and in response to determining that atrial oversensing is not detected. In addition, in some examples, an asynchronous ventricular pacing mode is selected in response to detecting both atrial oversensing and loss of conduction.

Abstract: In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.

Abstract: In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.

Abstract: Medical devices include a separate enclosure that houses a battery and electrically isolates the battery from external conditions such as any metal enclosures and ultimately isolates the battery from body fluids. Thus, the separate enclosure attaches to a housing of a medical device and provides for modularity of the battery which allows, for instance, different size batteries to be used with the same medical device design. The separate enclosure further prevents stimulation current from leaking back to the battery housing by providing the electrical isolation.

Abstract: A connector for an implantable electrical medical device includes a connector lumen defined in an elongated connector housing and adapted for receiving a portion of a lead. Connector-contact assemblies are disposed in the connector lumen. Each of the connector-contact assemblies includes a contact housing. Multiple connector contacts are arranged along perimeters of inner surfaces of the contact housings such that the connector contacts are not in electrical contact with one another. Each of the connector contacts includes a biasing structure that physically contacts terminals disposed along the lead when the lead is received by the connector lumen. For each connector contact of a particular connector-contact assembly, the biasing structure extends around no more than 70% of the perimeter of the inner surface of the contact housing and is circumferentially-offset from the biasing structures of the remaining connector contacts of the connector-contact assembly.

Abstract: Methods of making an implantable pulse generator are disclosed herein. The implantable pulse generator can include a body defining an internal volume and a plurality of wires extending from out of the internal volume of the body. Some of these wires can be connected, either directly or indirectly to a lead via a welded joint. The welded joint can be created by first resistance welding and then laser welding some of the wires to a connector.

Abstract: Medical devices include deformable structures that contact a lead upon being compressed. A grip that a clinician may grasp and manipulate is engaged with a nose structure of a header block of the medical device, and manipulation of the grip causes compression of the deformable structure to ultimately create fixation of the lead within the header block.

Abstract: Designs and methods of construction for a printed circuit board (PCB) in an implantable pulse generator (IPG) are disclosed which facilitate IPG PCB testing while also providing for protection of IPG circuitry in a simple and cost effective manner. The IPG PCB is formed as part of a larger test PCB, which includes an extender portion with traces routing nodes of interest in the IPG PCB to an edge connector. IPG electronics are mounted or soldered to the IPG PCB, and then such electronics are tested via the edge connector. The IPG PCB is then singulated from the extender portion in a manner leaving one or more PCB tabs at the severed edge of the PCB. The PCB tab(s) extend from the severed edge, and create an offset distance preventing traces severed and now exposed at the severed edge from contacting and potentially shorting to conductive structures in the IPG.

Abstract: Compliance voltage generation circuitry for a medical device is disclosed. The circuitry in one embodiment comprises a boost converter and a charge pump, either of which is capable of generating an appropriate compliance voltage from the voltage of the battery in the device. A boost signal from compliance voltage monitor-and-adjust logic circuitry is processed with a telemetry enable signal to selectively enable either the charge pump or the boost converter: if the telemetry enable signal is not active, the boost converter is used to generate the compliance voltage; if the telemetry enable signal is active, the charge pump is used. Because the charge pump circuitry does not produce a magnetic field, the charge pump will not interfere with magnetically-coupled telemetry between the implant and an external controller. By contrast, the boost converter is allowed to operate during periods of no telemetry, when magnetic interference is not a concern.

Abstract: Systems and methods for programming and logging medical device and patient data are provided. The systems include a handheld device, which is capable of communicating with a medical device, and a base station, which provides connectivity for the handheld device to accomplish various functions such as recharging, programming, data back-up and data entry. The methods comprise the steps of detecting a medical device, obtaining and recording information from the medical device. Additionally, medical device parameters may be modified and the recorded information may be archived for future reference.

Abstract: A system and method for modifying the parameters of an implantable medical device includes an implantable medical device that communicates with a remote control device that, in turn, communicates through the browser of a computer or any other device capable of using mark-up language protocol. The computer optionally communicates with other computers and/or devices through a network.

Abstract: A system and method for controlling non-paresthesia stimulation of nervous tissue of a patient. The method delivers a non-paresthesia stimulation waveform, senses sensory action potential (SAP) signals from the nervous tissue of interest, and analyzes the SAP signals to obtain SAP activity data for at least one of an SAP C-fiber component or an SAP A-delta fiber component. The method determines whether the SAP activity data satisfies a criteria of interest and adjusts at least one of the therapy parameters to change the non-paresthesia stimulation waveform when the SAP activity data does not satisfy the criteria of interest.

Abstract: An energy delivery device for emitting a combination of different types of energy. The device can emit pulsed electromagnetic fields (PEMF) energy and another type of energy, including pulsed electrical energy, heat energy, vibration, percussion, etc. The combined energy can provide both healing and pain therapy as well as therapy to shallow as well as deeper tissue.

Abstract: A wearable energy delivery system can be integrated with a wearable item to provide therapy to the user, including pain therapy, healing therapy, and muscle stimulation. Integration of the energy delivery system with apparel provides convenience to the user and allows hands free use of the system, which can be used during exercise or normal wear.

Abstract: A method of treating cancer cells in a tumor comprising: a) administering a pharmaceutical composition comprising: i) functionalized magnetic gold nanoparticles (GNP) coated with a polymer giving them a positive charge and ii) a pharmaceutically acceptable carrier therefore; and b) exposing the tumor to an intense and rapidly fluctuating magnetic field sufficient to induce eddy currents capable of hyperthermally ablating the cancer cells.

Abstract: An electromagnetic neural stimulation device includes a biocompatible shaft and one or more microcoil systems inside the shaft. A microcoil system includes a microcoil (driven externally) that is complemented with a metallic element juxtaposed against the microcoil as a shield to non-uniformly affect spatial distribution of the strength of the magnetic field generated by the microcoil. The microcoil system is oriented at a position inside the shaft that is predetermined to place the microcoil system in the vicinity of target neurons once the shaft is inserted into the biological tissue. The angular orientation of the microcoil system is optionally varied to selectively stimulate different regions of the neural network.

Abstract: The present invention relates to methods and compositions for modulating receptors in postsynaptic neurons of damaged or diseased retinas. The invention also related to methods for using the compositions set forth herein for treatment of diseases of hyperexcitability such as epilepsy.

Abstract: A device is presented for use in treatment of tissues inside a body cavity. The device comprises a probe member having at least a portion thereof carrying a plurality of light sources, at least said portion of the probe member having dimensions and shape suitable for insertion into a certain body cavity and for arranging within the surface thereof a three-dimensional array of said light sources, the light sources being configured and operable to irradiate optical energy outwardly from said probe member.

Abstract: A wearable device for therapeutic irradiation of skin may comprise: a light source optically coupled to a light spreading sheet and electrically coupled to a controller configured for controlling the intensity of light emitted from the light source and the duration of emission of light from the light source during a therapeutic session; a proximity sensor for detecting proximity of the light spreading sheet to the skin, the proximity sensor being attached to the light spreading sheet and electrically coupled to the controller; and a power source electrically coupled to the light source and the controller; wherein the controller is further configured to turn on, and keep turned on for the duration of the therapeutic session, the light source when the proximity sensor detects proximity of the light spreading sheet to the skin. In embodiments the light source may comprise an array of light emitting diodes attached to a substrate.

Abstract: Systems and methods comprising a light therapy luminaire adjustable to change a color temperature of light from the luminaire without changing the light to a non-white color; and software applications for receiving light exposure data to set a target color temperature for the luminaire. Calibration, sensors, software, and control processes for luminaires are taught.

Abstract: Disclosed is a therapy device for edema and neuropathy. Colored light within a visible light wavelength range, which is known to be useful for treating edema and neuropathy, is irradiated to a treatment area such as acupuncture points on a foot or a hand, or the surface of the skin, thereby relaxing the smooth muscle tissue of tissue cells with edema or neuropathy, facilitating peripheral vascular circulation and lymphatic circulation, and inducing the secretion of a material for treating edema and neuropathy.

Abstract: Disclosed herein are systems and methods for specifying treatment criteria and treatment planning parameters for patient specific radiation therapy planning. According to an aspect, a method includes receiving data about a patient, computing geometric characterization of one or more organs at risk proximate to a target volume of a patient or vice versa, and selecting relevant treatment knowledge and experience. The method also includes generating, based on the received data, computed geometric characterization, and available knowledge and experience, a first set of radiation treatment planning parameters that will lead to a high quality plan for the patient. Further, the method includes model-based prediction, based on the data, a second set or more of radiation treatment planning parameters that will lead to alternative achievable plans with different organ sparing objectives for treating the patient. The multiple sets for parameters can be used separately or in conjunction to generate treatment plans.

Abstract: The disclosed calibration method includes a calibration phantom positioned on an adjustable table on the surface of a mechanical couch, with the phantom's centre at an estimated location for the iso-centre of a radio therapy treatment apparatus. The calibration phantom is then irradiated using the apparatus, and the relative location of the center of the calibration phantom and the iso-centre of the apparatus is determined by analyzing images of the irradiation of the calibration phantom. The calibration phantom is then repositioned by the mechanical couch applying an offset corresponding to the determined relative location of the centre of the calibration phantom and the iso-centre of the apparatus to the calibration phantom. Images of the relocated calibration phantom are obtained, to which the offset has been applied, and the obtained images are processed to set the co-ordinate system of a stereoscopic camera system relative to the iso-centre of the apparatus.

Abstract: A surgical method uses a surgical instrument having an operative tip or end effector and an applicator of energy having an energy-transmitting interface, the applicator being different from the surgical instrument and separate therefrom. The method contemplates conducting an interventional procedure including steps of: (i) manipulating the instrument to place the operative or end effector in contact with bone tissue of a patient at a surgical site, (ii) using the surgical instrument to surgically operate on the bone tissue at the surgical site, (iii) prior to a termination of the procedure, manipulating the applicator to place the interface in contact with bone of the patient at or proximate the surgical site, and (iv) operating the applicator to apply, to the bone via the interface, energy with parameters of type, intensity, and duration selected for stimulating the healing of bone tissue.

Abstract: A method for minimally invasive surgery using therapeutic ultrasound in spine and orthopedic orthopedic procedures. The method includes a minimally invasive access port, a therapeutic ultrasound probe to treat a targeted area through the port, and a protective sheath that enables application of the therapeutic ultrasound without causing unintended tissue damage.

Abstract: A breathing mask having a face mask with a breathing port and a variable breathing resistance insert attached to the port. The insert includes an air resistance valve including a cap having a first plurality of apertures arranged in an arcuate arrangement, and a base attached rotatably to the cap and having a second plurality of apertures arranged in an arcuate arrangement. The cap is incrementally rotatable relative to the base between a first position, in which each of the first plurality of apertures of the cap is aligned with a corresponding one of the second plurality of apertures of the base, and a second position, in which one of the first plurality of apertures of the cap is aligned with one of the second plurality of apertures of the base, and the remainder of the first plurality of apertures of the cap is not aligned with any of the remainder of the second plurality of apertures of the base.

Abstract: A wearable scent suppression breathing mask configured to suppress the scents associated with an individual's breath. The breathing mask includes a face mask, an outer fabric layer overlaying the face mask, at least one air inlet valve assembly mounted within the face mask, and a plurality of air outlet valve assemblies mounted within the face mask and including at least one filter element to suppress the scent from an individual's breath. The at least one air inlet valve assembly is an inhalation permitting and exhalation restricting port, while the air outlet valve assemblies are inhalation preventing and exhalation permitting ports that control the flow of air.

Abstract: A traveller for safety line for a fall arrest system has a slot extending to the exterior of the traveller and a safety line locating shuttle provided on-board the traveller wherein the safety line locating shuttle is movable relative to the slot along a predetermined path in a direction across the slot. This aids in accurate positioning of the safety line with respect to the traveller. The slot can be defined between opposed slot edges which are movable relative to one another to reconfigure the slot.

Abstract: A system for suppressing a wind turbine fire using an admixture of hydrated super absorbent polymer having properties for suppressing and extinguishing of a fire. The admixture is non conductive and, upon drying, leaves a non-conductive residual that can be vacuumed from the wind turbine components to allow salvaging of the wind turbine components. The admixture is maintained within a pressurized storage vessel having a solenoid that is released by temperature sensor applying the admixture through strategically positioned nozzles to the control cabinets, generator, gearbox and bearings for extinguishment of any associated fire. Since the admixture of super absorbent polymer and water entraps the particulates and noxious and/or toxic gasses, the clean-up is substantially easier and quicker than the clean up from other methods of fire suppression and extinguishing.

Abstract: A standpipe assembly including a pair of elongated, side-by-side chambers each including a first end and a second end, a Y-valve including an inlet and two outlets, each outlet in fluid communication with a respective one of the first ends of the pair of chambers, a hose connection snoot in fluid communication with the second ends of the pair of chambers, and a valve handle operatively connected to the Y-valve, wherein the valve handle is positionable between a first position and a second position, in the first position, the valve handle is spaced apart from the pair of chambers by at least two inches, in the second position, the valve handle is spaced apart from the pair of chambers by less than two inches.

Abstract: A gas purging valve is operative to be connected to piping in a Fire Protection System (FPS) and to bleed gas at a predetermined rate. The valve includes an inlet in gas flow relationship with the FPS piping and a central passage in gas flow relationship with the inlet. The valve also includes a calibrated orifice removeably disposed in the central passage, in gas flow relationship with the passage and operative to allow a maximum predetermined gas flow rate therethrough. The valve further includes an outlet in gas flow relationship with the calibrated orifice. A ball is disposed upstream of the central passage. The ball is operative to allow gas flow through the gas purging valve but operative to impede the flow of water through the gas purging valve.

Abstract: A workout bag assembly including a tubular body having a closed end and an accessible end. The tubular body defines an interior divided into at least two compartments by a partition. The tubular body also has an exterior with two inner handles side-by-side along a length of the tubular body and two end handles. Each end handle is adjacent to a respective end. A partition divides an interior of the tubular body into a first compartment and a second compartment. Three tubes can receive a weighted material. The first compartment is sized and configured to snugly hold one of the three tubes when filled, and the second compartment is sized and configured to snugly hold two of the three tubes when filled.

Abstract: An exercise device for use by a user on a support surface comprises a support assembly, an extendable neck, and one or more resilient first resistance assemblies. The support assembly supports the user relative to the support surface. The support assembly includes a support body that is engaged by the user, and a support base that supports the support body, the support base resting on the support surface. The extendable neck is movably coupled to the support assembly. More particularly, the extendable neck is selectively movable relative to the support assembly between a retracted position and an extended position. The one or more resilient first resistance assemblies are secured to the extendable neck.

Abstract: An elastic resistance training apparatus for the performance of ankle plantar flexor resistance exercises, dorsi flexor resistance exercises, ankle inverter resistance exercises, or ankle everter exercises by a user. The apparatus comprises an elastic cord with a primary loop at each end configured to engage the dorsum and plantar surfaces of the user's foot. An auxiliary loop is connected to the primary loop and configured to engage the user's calcaneus bone when the primary loop engages the dorsum and plantar surfaces of the user's foot centering the apparatus at the talocrural joint to enable the user to perform talocrural joint movements without the apparatus disengaging from the user's foot during resistance exercises.

Abstract: A gravity ball comprises a ball body. The ball body is compounded by using multiple layers of spherocolloid. A woven-belt reinforcing rib is compounded on the surface of at least one layer of spherocolloid. The present invention has a rational structure, high strength and a long service and is difficult to damage.

Abstract: A variable weight toning strap having a flexible member and a plurality of generally rectangular sections, wherein each of the plurality of generally rectangular sections are disposed transversely along the flexible member length, include a top surface at least partially defining an upper surface of the flexible member, at least one perpendicular sidewall extending in a direction substantially perpendicular to the top surface, and a section width separating a rear face and a front face of the sections. Two of the sections have a discontinuous upper slit defined by the at least one perpendicular sidewall of each of said sections flanking the upper slit, wherein the upper slit spans the section width and terminates into a valley. The sections also define a plurality of channels therein, which house a plurality of weights, each selectively removably and frictionally retained by the respective plurality of channels.

Abstract: An exerciser and an elastic band. The exerciser includes first and second arms, a connector, and at least one elastic band. The first arm has a first body portion and first and second ends extending from the first body portion. The first body portion includes a first elongate slot and a first hinge portion disposed on opposite sides of the first body portion. The exerciser includes a second arm having a second body portion and first and second ends extending from the second body portion. The second body portion includes a second elongate slot and a second hinge portion disposed on opposite sides of the second body portion. The exerciser includes a connector rotatably coupling the first and second hinge portions of the respective first and second arms. The exerciser includes at least one elastic band formed as a continuous loop and disposed within the first and second elongate slots.

Abstract: A piece of fitness equipment, which is suitable for fitting to a body part of a person comprising a pressure chamber to which a fluid can be applied and a pump that is connected with the pressure chamber and is suitable for applying the fluid to the pressure chamber. Furthermore, the device comprises a controller for controlling the pump and a wearable holder that is detachably connectable with the pressure chamber and serves for holding the pressure chamber to the body part. The pressure chamber is formed in the shape of a hose.

Abstract: An interlocking tile system comprised of hinges within interlocking units permitting rapid installation, removal and reinstallation. The assemblies are usable on all surfaces of structures such as buildings and vehicles of all types, for impact cushioning, sound, heat, light and friction insulation.

Abstract: A cover, such as a towel, for covering an article, such as a mat, is described. The cover may comprise a first surface, a second surface disposed opposite of the first surface, and an article attachment means. When the cover may be in use with the article, the first surface may be in removable physical contact with a user and the second surface may be substantially physically contacting the article. The article attachment means may comprise at least one segment of material that may be removably attached over a portion of the second surface to at least one edge of the cover forming a hollow tube or a cavity, wherein either an article terminal end or at least one article corner may removably pass through the hollow tube or be removably held within the cavity such that slippage between the cover and the article are minimized.

Abstract: An exercise apparatus comprising a foot support movable by the user on the frame back and forth through any one of a plurality of complete, reproducible and different arc segments of a master arcuate path, the foot support being interconnected to an arc segment selection device that is manually actuatable to enable the user to manually select any one of the plurality of different arc segments.

Abstract: An exercise device, includes: a hollow cylindrical roller, two end plates fixable at the opposite ends of the roller the inner envelope of the roller and the end plates essentially defining a cavity, and each of the end plates further including centrally situated bearing arrangement, two supporting feet each having a first and a second support wherein: the first and the second support of the supporting feet are alignable at the end plates to set the supports at an angle relative to each other, and each of the supporting feet being fixable at the end plates of the roller by a fastening arrangement so that the supporting feet are at least functionally connected to the bearing arrangements of the associated end plates and the roller being rotatably fixed to the supporting feet.

Abstract: The present invention comprises a new and improved exercise device that is specifically adapted to assist a user engaged in abdominal crunches. The device comprises an elongated, arcuate board having a pair of handle grips extending from the sides thereof. Users engage the handles of the device and place their hands alongside their head during the crunch exercise. This is accomplished without placing strain on the neck. Rather than placing a tugging load on the back of the user's head, the board distributes this load across the back of the head, neck, and upper back of the user, thereby avoiding neck flexion. Overall, the device supports both the head and upper back, and eliminates neck pain when performing an abdominal crunch. The device includes adjustable side handles to ensure hands are properly placed, and stabilizes the head and neck while a person performs abdominal exercises. The device improves form during the exercise and improves core performance.

Abstract: An exercise apparatus for performing a back extension exercise comprising: a frame, a seat having a seating surface (PS) and a pelvic stabilization pad having a lower back engagement surface (ES), an input arm assembly interconnected by a first interconnection to a first resistance mechanism, the input arm assembly including a manually graspable mechanism and being arranged on the apparatus such that the input arm assembly is pivotable beginning from a start motionless position along a path of travel forwardly away from the pelvic stabilization pad under resistance exerted by one or both of the resistance mechanisms, wherein the first resistance mechanism is adapted to increase resistance as the degree of pivoting of the input arm assembly increases along the path of travel forwardly away from the pelvic stabilization pad.

Abstract: The invention relates to the field of sports equipment, and specifically to multi-functional wrist and hand expander-trainers, and can be used as a means for training wrist joints and for the effective execution of various training exercises aimed at a particular development of arm, body and leg muscles. The technical result is the uniqueness of design of the impact plyometric expander, allowing for the application of increased-concentration impact movements, plyometric exercises, energy accumulation, the development of explosive speed, and muscle neurostimulation; in addition, using the present expander makes it possible to gain kinetic energy, forcing individual muscle groups to experience various contractions (eccentric, isometric and concentric contractions) several times each.

Abstract: A sensor unit is mounted on a golf club which is one of sports equipments, and detects an inertial amount generated by a swing. In the sensor unit, a Z-axis serving as a detection axis of the inertial amount generated along a direction orthogonal to a surface located on the golf club side when the sensor unit is mounted on the golf club is set to extend along a direction S of the swing.

Abstract: A motion detection device which is attached to a motion body and detects a motion thereof, includes a sensor that detects the motion, and a holder that includes a fixation unit which is attached to the motion body so as to fix the sensor to the motion body, in which the holder further includes a first terminal that is provided at the fixation unit, and an antenna that is connected to the first terminal, and in which the sensor includes a second terminal that is electrically connected to the first terminal when attached to the holder.

Abstract: A wearable device assembly has a housing supporting a controller, display and indicator system thereon. The controller has at least one sensor wherein activity of a user wearing the device is detected. The controller selectively illuminates the indicator system to indicate a level of activity of the user.

Abstract: Systems and methods for electronically providing coaching feedback to a user during an athletic activity are disclosed. The method may include receiving electronic data, collecting second electronic data, generating comparison electronic speed data by comparing the second electronic speed data to the first electronic speed data, prompting the user.