Abstract: An electrolytic method for suppressing liquid eluent containing previously separated sample analyte anions, counterions to the sample anions, and non-sample anions suppressible to weak acids in an electrolytic device comprising a housing defining at least a sample stream flow channel and an ion receiving flow-through channel separated by an ion exchange bather. The sample stream flow channel includes an upstream channel portion and a downstream channel portion. A first current is applied across the upstream channel portion for substantially completely suppression. A second current is applied across the downstream channel portion at a magnitude of less than 10% of the magnitude of the first current.

Abstract: Systems and methods for detecting target chemicals are disclosed. A system includes a chemical sensor configured to filter light. The chemical sensor includes a referencing arm configured to output light at a first intensity level and a sensing arm sensitive to a target chemical. The sensing arm is configured to output light at a second intensity level. A difference between the first intensity level and the second intensity level indicates a presence of the target chemical.

Abstract: One example of testing for water contamination in geographic areas to determine a risk of water contamination includes determining a risk of water contamination. A computer system receives identification of a geographic area in which a risk of water contamination is to be determined. In response, the system determines a number of potential complaints of water contamination in the geographic area by applying the number of one or more correlated sources of water contamination located in the geographic area. The system determines a risk factor representing a risk of water contamination in the geographic area based, in part, on the number of potential complaints. The system can provide the risk factor as the risk of water contamination in the geographic area.

Abstract: A method of detecting an explosive material, and an analyzer and computer program products that may perform such methods. A method may include illuminating at least a portion of the material with light, and monitoring the temperature of the illuminated portion. T power or location of the illuminating light may be altered in response to the monitored temperature. Raman spectral data are produced in response to Raman radiation emitted from the portion in response to the light. The composition of the material may be analyzed based on the Raman spectral data or generating an indication to an operator that the material cannot be safely analyzed.

Abstract: A system and method is provided for non-invasively measuring changes in a specimen suspected of containing one or more microbes, by monitoring changes in the dielectric constant of the specimen caused by metabolic processes of such microbes.

Abstract: Described herein are compounds, methods, and kits for long-term tracking of cell proliferation, differentiation, and/or function. The compounds of the present invention are novel cell-tracking reagents, efficiently excitable with a 405-nm violet laser, that provide bright fluorescence intensity, uniform cell staining, and good retention within cells as well as low toxicity toward cells.

Abstract: In general, the present invention relates to identification of lipidome biomarkers for cancer analysis and it provides prognostic and predictive methods and kits for cancer diagnosis and subtyping and for diagnosing and/or predicting the evolution of a tumor and its response to lipid metabolism-targeted or other types of therapy in a subject, by making use of phospholipid (PL) profiling, wherein changes in the combined acyl chain length of intact body fluid-derived or tumor-derived phospholipid species is indicative of an elongation phenotype.

Abstract: The method according to the invention consists in providing a wafer having a bottom layer, a top first sacrificial layer and an insulating layer, structuring the first sacrificial layer to form a three dimensional structure onto which a first structural layer is deposited to define a corresponding three dimensional structure on the bottom surface of the first structural layer. The method consists also in forming a second three dimensional structure on the upper surface of the first structural layer.

Abstract: The invention relates to a method for detecting and measuring the presence of mono-nucleosomes and oligo-nucleosomes and nucleosomes that contain particular histone variants and the use of such measurements for the detection and diagnosis of disease. The invention also relates to a method of identifying histone variant biomarkers for the detection and diagnosis of disease and to biomarkers identified by said method.

Abstract: Methods for detecting one or more analytes, such as a protein, in a fluid path are provided. The methods include resolving, immobilizing and detecting one or more analytes in a fluid path, such as a capillary. Also included are devices and kits for performing such assays.

Abstract: A biochip includes a flat carrier and an array of spots containing catcher molecules which are arranged on the carrier. Each spot is associated with a microelectrode arrangement for impedance spectroscopic detection of binding events occurring between the catcher molecules and the target molecules applied via an analyte solution. In order to increase the sensitivity or the binding-specific measuring effects of the bio-chip, the electrode arrangement is at least partially embedded in a hydrophilic reaction layer containing catcher molecules and which is permeable to target molecules.

Abstract: The instant invention is to provide a method for detecting and measuring malaria infection utilizing the induction by hemozoin (HZ); a method for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection using the method for detecting and measuring; and a means for regulating the induction of innate immunity using the HZ, synthetic HZ, or derivatives thereof as an adjuvant or immunostimulant. Malaria infection is detected and measured of by detecting and measuring HZ-induced, TLR9-mediated, and MyD88-dependent innate immune activity. The detection and measurement of malaria infection can be used to diagnose malaria infection. The method for detecting and measuring is also used for screening a vaccine for malaria infection and a preventative or therapeutic agent for malaria infection. Further, HZ, synthetic HZ, or derivatives thereof are used as an adjuvant or immunostimulant to regulate HZ-induced innate immune induction.

Abstract: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Abstract: Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.

Abstract: A method for measuring the absolute amount of a target protein contained in a protein mixture, including the steps of: (A) fragmenting the sample containing the target protein and labeling with a stable isotope X; (B) adding a known amount of an internal standard that is prepared by fragmenting a standard protein that is identical to the target protein, and labeling with a stable isotope Y; (C) placing the sample in an LC-MS/MS device and performing multiple reaction monitoring (MRM) analysis using MRM transitions selected for the internal standard; and (D) identifying a peptide derived from the target protein (a target peptide) that shows the same retention time as a peptide derived from the internal standard (an internal standard peptide), and quantifying the target protein in the test sample by comparing the peak area of the internal standard peptide with the peak area of the target peptide.

Abstract: An in vitro method is described that uses full-thickness human skin for evaluating the influence of ABC transporters (such as MDR1, MRP1, MRP2 or BCRP) on the absorption and distribution of topically applied medicinal substances.

Abstract: A method of detecting a subject's cancer risk is provided. The method includes: gathering a sample of the subject's body water content via saliva; determining a ratio of cyanide within the subject's body water content and tissue saturation via saliva; providing a threshold cyanide ratio; comparing the ratio of cyanide within the subject's body water content and tissue saturation to the threshold cyanide ratio; and determining the patient's cancer risk based on the comparison of the ratio of cyanide within the subject's body water content to the threshold cyanide ratio.

Abstract: Example automated diagnostic analyzers and methods for using the same are disclosed herein. An example apparatus described herein includes a first carousel rotatably coupled to a base and having a first axis of rotation. The example apparatus includes a second carousel rotatably coupled to the base and vertically spaced over the first carousel such that at least a portion of the second carousel is disposed over the first carousel. In the example apparatus, the second carousel has a second axis of rotation and a plurality of vessels. The example apparatus also includes a pipetting mechanism offset from the second axis of rotation. The example pipetting mechanism is to access the first carousel and the second carousel.

Abstract: A sample analyzer comprises a reaction tray, a sample/reagent tray, and a probe. The reaction tray performs a first number of stops and rotations during an operating cycle, wherein the first number is configured to cause each of the reaction vessels to stop once at a position for the test before any of the number of the reaction vessels stops at the position for a second time. The sample/reagent tray rotates one of a sample container and reagent containers to a sample/reagent retrieving position during an operating cycle. The probe dispenses test sample(s), first reagent, and second reagent during different periods in different stop periods during an operating cycle. A method for analyzing samples is also disclosed.

Abstract: An accelerometer device for reducing stress on the sensor resulting from temperature extremes and multiple coefficients of thermal expansion. An exemplary accelerometer device includes upper and lower stators and a reed. The reed includes a support ring and a paddle that is flexibly connected to the support ring. The support ring includes a ring section and at least two mounting devices. The mounting devices are at least partially mechanically isolated from the ring section. The ring section flexibly receives the paddle. The mounting devices include a pad area and a neck area that connect the pad area to the ring section. The neck area includes a width dimension that is narrower than a diameter dimension of the pad area.

Abstract: A sensor device includes a first CMOS chip and a second CMOS chip with a first moving-gate transducer formed in the first CMOS chip for implementing a first 3-axis inertial sensor and a second moving-gate transducer formed in the second CMOS chip for implementing a second 3-axis inertial sensor. An ASIC for evaluating the outputs of the first 3-axis inertial sensor and the second 3-axis inertial sensor is distributed between the first CMOS chip and the second CMOS chip.

Abstract: A clamp sensor detects a detected value for a clamped object and includes: a main body with two main surfaces and two side surfaces; first and second clamp units whose front ends can open and close and form a ring-shaped body surrounding the clamped object; and an opening/closing mechanism for the clamp units. The first clamp unit is fixed to the main body at one side surface. The second clamp unit has a base end rotatably supported by a support shaft disposed toward the other side surface. The opening/closing mechanism includes: a biasing member biasing the second clamp unit to open the clamp units; and a sliding portion disposed on the other side surface and capable of sliding along the length of the main body. When slid toward the clamp units, the sliding portion presses the second clamp unit to close the front ends.

Abstract: A torque index sensor according to an embodiment of the present invention includes a rotor rotating with the first shaft which is one of an input shaft and an output shaft having a first magnet on an outer circumferential surface thereof, a stator disposed on an outer side of the first magnet and rotating with the second shaft which is the other of the input shaft and the output shaft, a shield disposed on a lower side of the stator and rotating with the second shaft and a second magnet combined with a lower side of the shield and rotating with the second shaft. The torque index sensor shields magnetic field interference and improves operational reliability.

Abstract: A thermal controller includes a thermal control interface to receive test data from an automated test equipment (ATE) system and dynamically adjust a target setpoint temperature based on the data and a dynamic thermal controller to receive the target setpoint temperature from the thermal control interface and control a thermal actuator based on the target setpoint temperature.

Abstract: An electrical current transducer comprising a housing, at least one magnetic core comprising an air gap and defining a central passage configured to receive a primary conductor carrying a primary current to be measured through the central passage, a magnetic field detector positioned at least partially in the air gap, and a grounding element. A lateral surface of the magnetic core is positioned against the grounding element without direct fixed attachment between the magnetic core and the grounding element, and the grounding element overlaps the magnetic core to an extent configured to ensure that a capacitive coupling (C3) between the magnetic core and the grounding element is greater than a capacitive coupling (C2) between the magnetic core and the magnetic field detector.

Abstract: A voltage sensing circuit of a converter senses input and output voltages of a converter with only one sensing circuit. The voltage sensing circuit is capable of reducing the number of the components for a controller and the volume thereof to save cost, and detecting whether the discontinuous mode (DCM) is entered or not, thereby to apply a separate control algorithm thereto when the DCM is entered.

Abstract: A current sense resistor and a method of manufacturing a current sensing resistor with temperature coefficient of resistance (TCR) compensation are disclosed. The resistor has a resistive strip disposed between two conductive strips. A pair of main terminals and a pair of voltage sense terminals are formed in the conductive strips. A pair of rough TCR calibration slots is located between the main terminals and the voltage sense terminals, each of the rough TCR calibration slots have a depth selected to obtain a negative starting TCR value observed at the voltage sense terminals. A fine TCR calibration slot is formed between the pair of voltage sense terminals.

Abstract: A method and device are disclosed for estimating a power demand level of an active circuit on a power supply line. A ripple amplitude and a ripple frequency associated with operation of the active circuit may be monitored on the power supply line. The ripple amplitude and ripple frequency may be compared with corresponding references. The ripple amplitude and ripple frequency may be associated with an estimated power demand level of the active circuit on the power supply line based on the comparison. A ripple generator generates a controlled ripple on the power supply line for calibration.

Abstract: The invention relates to an apparatus and method for tracking energy consumption. An energy tracking system comprises at least one switching element, at least one inductor and a control block to keep the output voltage at a pre-selected level. The switching elements are configured to apply the source of energy to the inductors. The control block compares the output voltage of the energy tracking system to a reference value and controls the switching of the switched elements in order to transfer energy for the primary voltage into a secondary voltage at the output of the energy tracking system. The electronic device further comprises an ON-time and OFF-time generator and an accumulator wherein the control block is coupled to receive a signal from the ON-time and OFF-time generator and generates switching signals for the at least one switching element in the form of ON-time pulses with a constant width ON-time.

Abstract: A system and method for determining loading of a filter having a first dielectric constant with a material having a different dielectric constant, is disclosed. The filter is contained within a metallic container forming a microwave cavity, and microwave or RF energy is created within the cavity and changes in the cavity microwave response are monitored. The changes in cavity microwave response are related to filter loading. In a preferred embodiment, the microwave energy includes multiple cavity modes thereby allowing determination of spatial distribution of the contaminant material loading. In one embodiment, the microwave cavity response includes a shift in frequency of a resonant mode. Alternatively, the microwave cavity response includes a shift in quality factor Q of a resonant mode. The microwave cavity response may include a shift in amplitude or peak width of the microwave's signal at resonance.

Abstract: A capacitive sensor includes a switching capacitor circuit, a comparator, and a charge dissipation circuit. The switching capacitor circuit reciprocally couples a sensing capacitor in series with a modulation capacitor during a first switching phase and discharges the sensing capacitor during a second switching phase. The comparator is coupled to compare a voltage potential on the modulation capacitor to a reference and to generate a modulation signal in response. The charge dissipation circuit is coupled to the modulation capacitor to selectively discharge the modulation capacitor in response to the modulation signal.

Abstract: A single-layer two-dimensional touch sensor includes a substrate and a flexible printed circuit board. First and second electrodes forming capacitor structures are disposed on the substrate. The first electrodes are arranged in a first direction. A group of second electrodes is disposed between each two adjacent first electrodes. The second electrodes are arranged in a head-to-tail meshed fashion in a second direction perpendicular to the first direction. In each group of second electrodes, lead lines of all second electrodes directly lead out to the flexible printed circuit board, and lead lines of the second electrodes at the same place in different group are short-connected at a node on the flexible printed circuit board. This touch sensor is a mutual capacitance structure which supports multi-point detection and increases the detection accuracy. In addition, no jumper wire is required on the substrate, which reduces the requirements of the fabrication process.

Abstract: The electric circuit evaluation method according to the present invention comprises: a step for finding a malfunction power frequency property, in which the magnitude of a critical noise signal at which a designated electric circuit causes a malfunction is represented by the power injected into the designated electric circuit; and a step for finding a malfunction current frequency property, in which the magnitude of the critical noise signal at which the designated electric circuit causes a malfunction is represented by a current (I_LSI) flowing to a predetermined portion of the designated electric circuit, and a malfunction voltage frequency property, in which the magnitude of the critical noise signal at which the designated electric circuit causes a malfunction is represented by a voltage (V_LSI) occurring between predetermined points of the designated electric circuit, both of which properties found from the malfunction power frequency property.

Abstract: Systems and methods for cabling verification may include one or more operations including, but not limited to: receiving floor plan data representing a floor plan of a premises; receiving at least one user input specifying a location of at least one cabling endpoint relative to the floor plan; receiving at least one user input selecting at least one cabling verification test for the at least one cabling endpoint; receiving one or more cabling verification test results for the at least one cabling endpoint obtained by at least one testing device; and updating at least one database element associated with the at least one cabling endpoint and maintained by the cloud-based server.

Abstract: A leakage detector is provided with the addition of an output control circuit that monitors a circuit wire-to-ground voltage, which is at the root of a suffered operation and produced between a transformer B-class grounding phase of a monitored circuit and a D or C-class grounding electrode or a ground structure etc. of an electrical equipment connected to the grounding electrode, execute a phase judgment of a leakage current detected by a zero-phase current transformer on the basis of the monitored voltage, and stop an output operation of the leakage detector when the leakage current is a suffered current flowing from a load side L of the detecting zero-phase current transformer toward the power side K, i.e. the transformer and when the circuit wire-to-ground voltage exceeds an appropriately-established dynamic sensitivity voltage value.

Abstract: Provided is a method of detecting a state of a power cable in an inverter system. The method includes detecting a direct current (DC)-link voltage value of a DC-link capacitor included in an inverter, detecting a battery voltage value of a battery supplying a DC power to the inverter, comparing the DC-link voltage value with the battery voltage value, and determining the state of the power cable connecting the inverter to the battery to be abnormal when a difference between the DC-link voltage value and the battery voltage value is out of a preset range.

Abstract: This disclosure relates to the field of current transformers, for testing the excitation characteristic of a current transformer is disclosed. The method comprise applying alternately positive and negative DC voltages across terminals of secondary winding of a CT to be tested and acquiring a secondary current; constructing a mathematical model of the relationship between the secondary current and a root mean square (rms) equivalent voltage at rated frequency of the CT from the relationship between a magnetic flux of a secondary winding iron-core of the CT and the rms equivalent voltage; and generating an excitation characteristic curve according to the mathematical model. The method and apparatus of the embodiments may test CTs requiring lower testing voltage as well as CTs with knee-point up to tens of kV by supplying a relatively low voltage and power, which makes the embodiments widely applicable.

Abstract: An instrument for detecting partial electric discharges includes: an input stage set up to receive a discharge signal representative of one or more partial discharge pulses and a sync signal representative of an alternating voltage applied to the electric apparatus; a data processing stage for receiving the discharge signal and the sync signal, and extracting substantially in real time for each pulse detected the value of an amplitude parameter, correlated with a pulse amplitude, and the value of a phase parameter, representative of the phase of the voltage applied to the electric apparatus concurrently with the pulse, and transferring to output a processed digital signal including the values extracted. The processing stage includes a filtering module set up to disable substantially in real time the transfer to output of the values of the parameters extracted for one or more pulses.

Abstract: An apparatus for determining solar cell characteristics includes a quantum efficiency measurement tool configured to measure an external quantum efficiency of the solar cell and a reflectivity measurement tool configured to measure the reflectivity of the solar cell. The apparatus also includes a capacitance measurement tool configured to measure the capacitance of the solar cell and a processor configured to calculate a diffusion length of the solar cell based on the measured quantum efficiency, reflectivity and capacitance of the solar cell.

Abstract: A semiconductor test system includes test head pins; per-pin resources which are connectable to the test head pins on a one-to-one basis; shared resources, each of which is connectable to one of the test head pins; a tester controller for controlling the per-pin resources and the shared resources; and a tabular-form test plan including: a first column for specifying a measurement function that uses at least one of the per-pin resources and the shared resources; and at least one second column for specifying input and output parameters of the measurement function, the tabular-form test plan further including program rows, the tabular-form test plan being executed by the tester controller, the tabular-form test plan further including a third column for specifying how rows that are executed by asynchronous parallel execution are to be grouped.

Abstract: The systems and method described herein provide efficient (e.g., low power and low area) techniques to track performance in numerous supply domains with heterogeneous circuits that are used in a large system-on-a-chip integrated circuit (SoCs). The heterogeneous circuits can include circuits made with different devices, different cell libraries, and different hard macros that are in different power supply domains. Performance measurements from performance sensors (or process-voltage-temperature (PVT) sensors) that are spread about the SoC are collected and processed to determine voltage levels for each of the supply domains. A single controller can receive can determine voltage levels for a whole SoC. The performance sensors are connected to the controller by a scan chain. The techniques are flexible and can be easily adapted for use in SoCs with different power supply domains and types of circuits.

Abstract: An apparatus includes a probe card having a probe board with a conductive path electrically connected to a tester and probes enabling to respectively contact connection pads of a semiconductor wafer on a chuck top and moving relatively to the chuck top, and an elastic heat conducting member arranged between a working surface of the chuck top or the semiconductor wafer on the working surface and the probe board. The elastic heat conducting member can abut on the working surface of the chuck top or the semiconductor wafer on the working surface and the probe board when the probes do not abut on the respective corresponding connection pads and is elastically deformable not to prevent abutment between the probes and the respective corresponding connection pads.

Abstract: An electronic device with COF package is provided. The electronic device includes a flexible substrate, a core circuit unit, multiple output pads, multiple switching elements, and a common test pad. The flexible substrate includes a non-cutting-out area and a cutting-out area. The core circuit unit and output pads are disposed in the non-cutting-out area. First terminals of the switching elements are respectively and electrically connected to output pads of the core circuit unit, and second terminals of the switching elements are respectively and electrically connected to the output pads. The common test pad is disposed in the cutting-out area and electrically connected to the output pads. In a test stage, the switching elements are sequentially turned on such that one of multiple output signals of the core circuit unit is transmitted to the common test pad.

Abstract: In order to detect and locate defects, or faults, in a plurality of chips or other circuits sharing a common design, said chips are each tested for incorrect outputs, or failures, in response to inputs. The incorrect outputs are then collectively diagnosed in a single simulation by simulating a series of suspected fault candidates on a simulated chip of the chip design, and afterward comparing the incorrect outputs generated by each fault candidate to the incorrect outputs of the individual chips, to determine if a fault candidate generates all failures for a chip and no others. The test inputs and expected outputs may be predetermined through Automatic Test Pattern Generation. The fault candidates may be determined by use of a backtrace process such as back cone tracing. The failures may be recorded in association with a measure point, the input pattern that resulted in the failure, and the failure value.

Abstract: A battery system comprises at least two modules which include a plurality of battery cells, with each module being associated with a cell voltage detection unit which is connected to a central controller via a common communication bus. Each module additionally includes a module voltage detection unit which is connected to the central controller and is configured to separately detect the voltage of the associated module.

Abstract: A method and a device for determining the actual capacity of a battery uses a set of characteristic curves, wherein at the start of a discharge process the initial voltage of the battery, the magnitude of the discharge current and the temperature of the battery are determined. From this, by comparison with the data provided in the set of characteristic curves, a characteristic curve is selected and an initial state of the battery is determined. At the end of the discharge process, the final voltage of the battery is measured. The final voltage is compared, at the end of the discharge, with the voltage expected based on the selected characteristic curve and, in the event that the final voltage is smaller than the voltage expected based on the discharge process, it is determined that the actual capacity of the battery is smaller than the available capacity assumed at the start of the discharge process.

Abstract: A system and method for testing multiple power supplies. Multiple power supplies are received including a power-end and an adapter end for connection to a power supply tester. Programmable loads and test parameters are configured for the power supply tester in response to a user selection. The multiple power supplies are automatically tested utilizing the test parameters. Performance characteristics of the multiple power supplies are measured during testing. The performance characteristics of the multiple power supplies are recorded. Results indicating whether each of the multiple power supplies passed the testing are displayed utilizing one or more displays and light emitting diodes.

Abstract: A current sensor includes first and second magnetic sensors that are placed around a current line through which a current flows so that the current line is positioned therebetween, and that detect an induction field generated by the current. Each of the first and second magnetic sensors has a main sensitivity axis and a sub-sensitivity axis. The direction of the main sensitivity axis of each of the first and second magnetic sensors is oriented in a direction that is not orthogonal to the direction of the induction field. The directions of the main sensitivity axes of the first and second magnetic sensors are oriented in the same direction and the directions of the sub-sensitivity axes are oriented in the same direction, or the directions of the main sensitivity axes are oriented in opposite directions and the directions of the sub-sensitivity axes are oriented in opposite directions.

Abstract: An electric current-spin current conversion device according to the invention performs conversion between electric current and spin current utilizing the spin Hall effect or the inverse spin Hall effect of a 5d transition metal. A spin accumulation apparatus according to the invention includes a non-magnetic body in which injected spins are accumulated and an injection unit that injects spins into the non-magnetic body, wherein said injection unit comprises said electric current-spin current conversion device provided on said non-magnetic body, and an electric power source that supplies an electric current to said electric current-spin current conversion device in such a way that a spin current flowing toward said non-magnetic body is generated by the spin Hall effect.

Abstract: A method of attenuation correction for a positron emission tomography (PET) system includes obtaining PET scan data representative of a volume scanned by the PET system, obtaining a plurality of magnetic resonance (MR) scan data sets representative of the volume, each MR scan data set being acquired in a respective time period during acquisition of the PET scan data by the PET system, detecting motion of the volume that occurred during the acquisition of the PET scan data based on an assessment of the plurality of MR scan data sets, the PET scan data, or the plurality of MR scan data sets and the PET scan data, determining attenuation correction data from the plurality of MR scan data sets based on the detected motion for alignment of the attenuation correction data and the PET scan data, and correcting the PET scan data with the attenuation correction data.