Abstract: A heat resistant sheath for endoscope includes a main body sheath into which an insertion portion of an endoscope apparatus is inserted, and into which a cooling fluid is supplied by a cooling device, a sheath distal end portion at which an endoscope distal end portion is arranged, and that is connected to a distal end of the main body sheath, an observation hole formed at a middle part of a circumferential side portion of the sheath distal end portion, and configured to expose an observation window of the endoscope distal end portion to allow observation of an object, and an exhaust hole formed in the circumferential side portion of the sheath distal end portion, on a distal end side with respect to the observation hole, and configured to discharge the cooling fluid in a direction different from an observation direction of the endoscope apparatus.

Abstract: Electric power of a required voltage is supplied to an endoscope distal end portion, and a distal end temperature is prevented from being higher. An imaging device having an imaging element, and its peripheral circuit and a first circuit part including a first regulator as a power circuit are built in the endoscope distal end portion. The first circuit part is connected to a second circuit part via a cable. The second circuit part includes a second regulator supplying electric power to the first regulator. By the overcurrent detection function of a temperature detecting unit or a regulator arranged, when at least one abnormality of a temperature abnormality and an overcurrent in the distal end portion is detected, the output of at least one of the first regulator and the second regulator is stopped, and supply of power to the distal end portion is stopped.

Abstract: The fog-free dental mirror uses compressed air directed at and over the surface of the mirror to provide a protective air stream over the surface of the mirror to avoid the accumulation of moisture while keeping debris off of the surface of the dental mirror. The handle of the mirror is preferably aluminum, is multi-positionable and is ergonomically designed and allows for the novel regulation of airflow and quick connection of multi-positional mirror heads. The new and unique dental mirror is fully auto-clavable. Air flow level is settable by an actuator and retains its position with the set air flow even if the user releases pressure therefrom and even after a full blast of air is executed.

Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the ax

Abstract: Methods of applying OCT angiography are disclosed. In particular, methods of detecting, visualizing and measuring the extent of retinal neovascularization are disclosed. Further disclosed are methods measuring retinal nonperfusion area and choriocapillaris defect area.

Abstract: Methods and systems for determining a physiological parameter of a subject through interrogation of an eye of the subject with an optical signal are described. Interrogation is performed unobtrusively. The physiological parameter is determined from a signal sensed from the eye of a subject according to a schedule, under the control of a scheduling controller.

Abstract: An OCT system for imaging multiple depth positions includes a light source, a sample arm and two or more reference arms. The sample arm propagates light to the object and directs object return light having a first return light beam from a first position and a second return light beam from a second position, the second return light having a dispersion level higher than the first return light beam by a dispersion difference amount. The first and second reference arms produce light beams having substantially the same dispersion as the first and second return light beams, respectively. The optical pathway combines all of the object return light and the reference light beams. An OCT detector measures the resulting interferogram. Imaging information is obtained for both the first position and the second position based on the dispersion difference amount.

Abstract: An inflatable mask with two ocular cavities can seal against a user's face by forming an air-tight seal around the periphery of the user's eye socket. The sealed air-tight ocular cavity can be pressurized to take ocular measurements. The mask can conform to the contours of a user's face by inflating or deflating the mask. In addition, the distance between the user and a medical device (e.g. an optical coherence tomography instrument) can be adjusted by inflating or deflating the mask. Also disclosed herein is an electronic encounter portal and an automated eye examination. Other embodiments are also described.

Abstract: In certain embodiments, determining biometric properties of an eye includes emitting a measuring light beam. The measuring light beam is guided towards the eye for a plurality of scans. For each scan, the measuring light beam enters the cornea in a first lateral region and reaches the retina of the eye in a second lateral region along a corresponding beam path. The beam paths are different from each other. The measuring light beam back-reflected from the eye for each scan is interferometrically analyzed to provide corresponding OCT data. At least one of the following is determined according to the OCT data: at least one distance from a surface of the retina to a surface of the cornea or to a surface of the lens of the eye.

Abstract: An adaptive optical imaging system for imaging an object including a first polarization sensitive spatial light phase modulator and a second polarization sensitive spatial light phase modulator and a polarization adjustment device that converts the polarization of light that has passed through the first modulator before it irradiates the object and converts the polarization of the reflected light before it passes through the second modulator.

Abstract: Embodiments include methods, systems and computer program products for monitoring a user of a helmet for a traumatic brain injury. Aspects include monitoring one or more eyes of the user with a camera embedded in the helmet and analyzing, by a processor, one or more characteristics of the one or more eyes of the user.

Abstract: The present invention discloses an eye motion sensing method, a flexible contact body, an external sensing coil, and a system. The method may include: sensing an eye motion by using a servo motion signal of a permanent magnet implanted into a flexible contact body; applying at least four coils disposed externally on a same plane, and monitoring a servo motion of the permanent magnet according to an electromotive force in the coils; and converting the electromotive force to restore an eye motion signal. The present invention can use the sensing coils distributed around an eyepit to detect the electromotive force generated when the eye motion leads to the servo motion of the flexible contact body, and analyze the electromotive force. Accordingly, the eye motion triggered by a perceptual task can be analyzed objectively.

Abstract: According to one embodiment, an ophthalmic microscope system includes an illumination system, a pair of light-receiving systems, and an irradiation system. The illumination system is configured to irradiate a subject's eye with illumination light. Each of the light-receiving systems includes a first objective lens and a first imaging device, and is configured to guide the illumination light returning from the subject's eye to the first imaging device through the first objective lens. The objective optical axes of the light-receiving systems are not parallel to each other. The irradiation system is configured to irradiate the subject's eye with light different from the illumination light from a direction different from the objective optical axes.

Abstract: According to one embodiment, an ophthalmic microscope includes an illumination system, a pair of light-receiving systems, and a first mechanism. The illumination system is configured to irradiate a subject's eye with illumination light. Each of the light-receiving systems includes a first objective lens and a first imaging device, and is configured to guide return light of the illumination light returning from the subject's eye to the first imaging device through the first objective lens. The objective optical axes of the light-receiving systems are not parallel to each other. The first mechanism is configured to move the light-receiving systems relative to each other to change an angle formed by the objective optical axes of the light-receiving systems.

Abstract: A multimode fundus camera enables three-dimensional and/or spectral/polarization imaging of the interior of the eye to assist in improved diagnosis. In one aspect, the multimode fundus camera includes a first imaging subsystem, a filter module, and a second imaging subsystem. The first imaging subsystem is positionable in front of an eye to form an optical image of an interior of the eye. The filter module is positioned at a pupil plane of the first imaging subsystem or at a conjugate thereof. The second imaging subsystem include a microimaging array and a sensor array. The microimaging array is positioned at the image plane or a conjugate thereof, and the sensor array is positioned at the pupil plane or a conjugate thereof.

Abstract: A system for measuring and/or monitoring an analyte present in interstitial fluid in skin is provided. The system includes a substrate that may be implanted into the skin and a reader device. The substrate includes a sensor comprising aptamer conjugates and is configured to obtain one or more measurements related to at least one analyte in interstitial fluid. The reader device is configured to detect the analyte in interstitial fluid via interaction with the substrate.

Abstract: A wireless power receiver includes a rectifier coupled to an antenna which is configured to receive a wireless power signal, and convert the wireless power signal to a direct current input signal. A direct current-to-direct current converter generates a direct current output signal based in part on the direct current input signal and a pulse-width modulation signal. A pulse modulator is configured to adjust an alternating current impedance of the wireless power receiver by modifying, based in part on the direct current input signal, a duty cycle of the pulse-width modulation signal to the direct current-to-direct current converter. A monitoring device is in communication with the rectifier and the pulse modulator. The monitoring device has one or more sensors and a unique user ID. The one or more sensors acquire user information selected from of at least one of, a user's activities, behaviors and habit information.

Abstract: A toothbrush uses light to deliver an oral care benefit such as the detection of plaque or the whitening of teeth. In one embodiment, a toothpaste formulation contains ultraviolet brighteners as a whitening ingredient that has a whitening or bleaching effect when in contact with ultraviolet radiation. The activation of the brighteners may occur through the use of a toothbrush having a UV source. In yet another embodiment, a toothpaste formulation contains an oxidizing agent as a whitening ingredient, the activation of which occurs through the use of a toothbrush having a source of light energy which includes LEDs in the bristle field.

Abstract: What is disclosed is a system and method for detecting cancerous tissue in breast tissue using a thermal image. In one embodiment, the present tumor detection method involves selecting a region of interest in the thermal image to be processed for breast cancer screening. Thereafter, a percentage of pixels p1 in the selected region having a temperature Tpixel1, where T1?Tpixel1?T2, is determined. A percentage of pixels p2 in the selected region having a temperature Tpixel2, where T3T?Tpixel2, is determined. A ratio p3=Pedge/Pblock is also determined, where Pedge is a number of pixels around a border of a suspected tumor within the selected region, and Pblock is a number of pixels in a perimeter of the selected region. A decision fusion rule R, as more fully disclosed herein, is utilized to determine, based on these determination whether tissue within that region is cancerous, or non-cancerous, or is suspicious of being cancerous.

Abstract: Devices, systems, and techniques for monitoring vascular disease of a user are disclosed. In some examples, a wearable device for monitoring chronic venous insufficiency of a user may include a band configured to couple the wearable device to a leg of a user, a strain sensor configured to generate strain information indicative of changes in circumference of at least a portion of the leg, an activity sensor configured to generate activity information indicative of one or more of an orientation or a movement of the leg, and a processor configured to output user information indicative of the strain information and the activity information.

Abstract: Signals derived from the brain or cerebral cortex are extracted by separating and removing influence of the skin blood flow included in NIRS signals. Provided is a biophotonic measurement apparatus to separate signals simultaneously measured with a plurality of irradiator-detector distances (SD distances) into brain blood flow-derived signals and skin blood flow-derived signals using SD distance dependency of signal amplitudes.

Abstract: The technology described in this document can be embodied in a method that includes receiving optical data including information associated with a subject, and determining from the optical data, a first dataset and a second dataset. The first dataset represents time-varying color change at a first body part of the subject, and the second dataset represents time-varying characteristics at a second body part of the subject. The method includes identifying a first point in the first dataset, and a second point in the second dataset. The first point represents a time at which a pulse pressure wave traverses the first body part of the subject, and the second point represents a time at which the pulse pressure wave traverses the second body part of the subject. A pulse transit time (PTT) between the first and second body parts can be calculated as a difference between the first and second points.

Abstract: An apparatus for detecting biometric information includes a photo sensor configured to acquire a first signal by detecting a change in an optical signal with respect to an object; a pressure sensor configured to acquire a second signal by detecting a change of a pressure with respect to the object; a signal extractor configured to extract a waveform signal from at least one from among the first signal and the second signal based on signal sensitivities of the first and second signals; and a signal analyzer configured to analyze biometric information from the extracted waveform signal.

Abstract: A method of assembling an opto-physiological (OP) sensor comprises: (i) modelling the opto-physiological properties of at least one body tissue type to be monitored; (ii) determining, through application of the model, an optimal optical design for an opto-physiological (OP) sensor operable to monitor the opto-physiological properties of the at least one body tissue type; and (iii) making the OP sensor to the determined optical design. The optimal optical design for the OP sensor comprises: (i) determining the optimum separation of each of a plurality of light sources from a photodetector, based on modelled optical path lengths for light travelling from each light source, through the body tissue type to be monitored, to the photodetector; and (ii) locating light sources of different wavelengths at different distances from the photodetector.

Abstract: Technology for detecting whether a wearable device is misaligned is disclosed. The device can include a number of sensors, such as heart rate, temperature, or other sensors used to sense a physiologic aspect of the user, such as heart rate and can further contain components capable of providing data as to the proper alignment or placement of the wearable device on the user. The wearable device may communicate with a computing device, such as a mobile device which can receive data from the wearable device and output notifications to the user, including notifications about proper or improper placement or alignment of the wearable device.

Abstract: Technology for a wearable heart rate monitoring device is disclosed. The wearable heart rate monitoring device can include a heart rate sensor operable to collect sensor data, a modulator operable to generate a modulated signal that includes the sensor data, a housing configured to engage a body feature or surface in a manner that allows for heart rate detection, and a communication module configured to transmit the sensor data in the modulated signal to a mobile computing device via a wired connection that is power limited. The mobile computing device is typically configured to demodulate the modulated signal in order to extract the sensor data.

Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.

Abstract: A peripheral nerve conduction diagnosis system that utilizes an electrostimulation device having dry elastomer electrodes and a distance measuring device that allow a user to move the electrostimulation device along the skin of a patient while in constant contact with the skin and measure the distance moved.

Abstract: Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.

Abstract: According to at least one aspect, a wearable medical device is provided. The wearable medical device may include a sensing electrode to sense an electrocardiogram signal of a patient, a therapy electrode to provide treatment to the patient, a garment to be worn about a torso of the patient and receive the sensing electrode and the therapy electrode, and a controller operatively coupled to the sensing electrode and the therapy electrode. The controller may be configured to determine a current location of the wearable medical device based on a previous position of the medical device and at least a speed and a direction of movement of the wearable medical device.

Abstract: In one embodiment, a neurological status evaluation apparatus includes a signal generator configured to generate an electromagnetic signal at one or more frequencies, a transmitting antenna coupled to the signal generator and configured to transmit the electromagnetic signal, and a receiving antenna positioned proximate to the transmitting antenna such that an evaluation space is defined between the transmitting antenna and the receiving antenna. The biological tissue under evaluation does not contact the transmitting antenna or the receiving antenna. The receiving antenna receives a modulated electromagnetic signal after propagating through the biological tissue under evaluation. The neurological status evaluation apparatus further includes a spectrum analyzer coupled to the receiving antenna, wherein the spectrum analyzer receives and samples the modulated electromagnetic signal.

Abstract: In a system and method for reconstructing cardiac activation information, an analysis cardiac signal and a reference cardiac signal are accessed and processed to determine a first point of change in the analysis cardiac signal at which a derivative of the analysis cardiac signal diverges with respect to a derivative of the reference cardiac signal. The signals are processed to determine a second point of change in the analysis cardiac signal at which a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal. An activation onset time is assigned in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal.

Abstract: An electrocardiogram high pass filter (25) employs a baseline low pass filter (40), a signal delay (43) and a signal extractor (44). In operations, baseline low pass filter (40) includes a finite impulse response low pass filter (41) and an infinite impulse response low pass filter (42) cooperatively low pass filtering a baseline unfiltered electrocardiogram signal (ECGbu) to output a filtered baseline signal (BSef). Signal delay (43) time delays the baseline unfiltered electrocardiogram signal (ECGbu) to output a delayed baseline unfiltered electrocardiogram signal (ECGdbu), and signal extractor (44) extracts the filtered baseline signal (BSef) from the delayed baseline unfiltered electrocardiogram signal (ECGdbu) to output a baseline filtered electrocardiogram signal (ECGbf).

Abstract: The present invention provides apparatus and methods for determining the occurrence of a QRS complex in ECG data. According to an aspect of the present invention, an apparatus is proposed for determining the occurrence of a QRS complex in ECG data by utilizing a first, second and third set of ECG data that are acquired by respectively electrode leads II, V4 and V5 and by determining whether a QRS complex has been detected within the predefined temporal window in at least two of the first, second and third sets of ECG data. According to another aspect of the present invention, an apparatus is proposed for determining the occurrence of a QRS complex in ECG data by utilizing three sets of ECG data whose signal quality values V are the smallest three of the first to twelfth sets of ECG data that are acquired by respectively the standard 12 electrode leads and by determining whether a QRS complex has been detected within the predefined temporal window in at least two of the three sets of ECG data.

Abstract: A system to generate a representation of a rhythm disorder includes a plurality of sensors disposed at multiple locations spatially in relation to the heart, wherein cardiac information signals are sensed. A processor receives and analyzes the activation onsets of the cardiac information signals to determine an arrangement of activation onsets. A representation that indicates the clinical source of the rhythm disorder is generated based on the arrangement of the activation onsets.

Abstract: A wearable electrocardiography monitoring ensemble is provided, which includes a garment made of a compressible and elastomeric material. The garment is wearable about an upper region of the torso and further includes an internal structure forming a compressive bias circumferential to the torso. The ensemble also includes an electrode assembly provided on an inside surface of the garment on an underside of the internal structure. The electrode assembly has a pair of electrocardiography electrodes, a pair of terminated electrical connections that are each coupled to one of the electrocardiography electrodes, and a backing to which the electrocardiography electrodes are affixed.

Abstract: According to at least one aspect, a medical device is provided. The medical device includes at least one electrode to sense an electrocardiogram (ECG) signal of a patient and a controller coupled to the at least one electrode. The controller may be configured to generate a first ECG template based on a first ECG signal of the patient, generate a second ECG template based on a second ECG signal of the patient, and determine whether the patient is experiencing a cardiac event based on the ECG signal of the patient and an identified one of the first ECG template and the second ECG template.

Abstract: Methods and devices for identifying a treatment site are disclosed. The methods may include engaging a plurality electrodes with plurality of locations on or adjacent an interior wall of a patient. The methods may also include generating a pacing stimulus through a first pair of the plurality of electrodes and measuring a resulting electrical activity. The methods may also include identifying at least one site for treatment based on the resulting electrical activity. The devices may include elements configured to perform these methods.

Abstract: Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate distinguishing prostate cancer tissue from normal peripheral zone tissue based on quantitative data acquired using NMR fingerprinting in combination with apparent diffusion co-efficient (ADC) values or perfusion values acquired using DWI-MRI or DCE-MRI.

Abstract: Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, locating, tracking, monitoring, deflating, and retrieving the same are provided.

Abstract: This document describes a system for determining positioning of an intubation tube in a patient. The system can include a first acoustic sensor configured to be disposed to listen to one of a lung and a stomach of the patient and to provide a first signal. The system includes a signal processing unit, coupled to the first acoustic sensor, configured to analyze spectral components of the first signal and determine whether a frequency of the spectral components of the first signal are characteristic of sounds induced by ventilation via the intubation tube of airflow to the lung or the stomach of the patient.

Abstract: A mechanism is described for facilitate dynamic and seamless breath testing at computing devices according to one embodiment. A method of embodiments, as described herein, includes detecting air exhaled by a user into a first computing device, where the air includes breath associated with the user. The method may further include sensing the breath in the air, obtaining a sample of the breath, and evaluating the sample, and generating a message based on the evaluation of the sample. The method may further include presenting, via one or more output components, the message to the user via a user interface, where the message includes results of the evaluation of the breath sample.

Abstract: Systems, methods, and devices relating to a sensor array for use with a user's finger segment and which indirectly maps the topography of a surface under the finger segment. Each sensor array is worn on a user's finger segment and has multiple sensitive strain gauges as well a positioning sensor. The multiple strain gauges are deployed around the periphery or sides of the finger segment. Each strain gauge measures the deformation of the finger segment pad as the finger segment passes over the surface topography. The relative ratios of the deformation detected indicates the location of a feature or contact point on the topography relative to the group of strain gauges. The positioning sensor determines the array's orientation as well as its location relative to a predetermined global reference frame.

Abstract: Embodiments include methods, systems and computer program products for monitoring a person for a traumatic brain injury. Aspects include monitoring a gait of the user with one or more accelerometers embedded in the uniform and analyzing, by a processor, one or more characteristics of the gait of the user. Aspects also include determining whether the one or more characteristics of the gate indicate that the user may have suffered the traumatic brain injury and creating an alert that the user of the helmet may have suffered the traumatic brain injury.

Abstract: A method implemented in a system which comprises a lightweight personal wearable monitoring device, supplied by a battery, comprising an accelerometer, a processing unit, a display, a remote server, said method comprising the steps: /a/ collecting, from a plurality of individuals caused to practice various physical activities from a set of predefined activities, acceleration data from sensing devices placed on each of said individuals, /b/ defining N small data-size specific metrics, computed from acceleration signals, which allow to define a global activity classifier, /c/ acquiring, at a first monitoring device worn by a first user, acceleration signals from the accelerometer of the first monitoring device, /d/ calculating, at the first monitoring device, over each lapsed time unit T1, specific metrics values from the sensed signals, to form a series of specific metrics values, /e/ send them to the processing unit, /f/ allocate an activity type for each time unit together with corresponding specific metric

Abstract: The present invention discloses a method and an apparatus for precisely perceiving an indoor activity. The method may include: receiving a vibration signal on a floor by using multiple vibration sensors disposed according to a preset rule; and determining a location of a vibration source according to a phase difference of a vibration signal of the same vibration source in different vibration sensors. The monitoring performed on the indoor activity in the present invention can be performed without disturbing the monitored person, and can resolve the concern about leakage of privacy of the monitored person.

Abstract: Methods, systems and devices for linking devices to tracking devices are provided. One method includes scanning, by an activity tracking device, for a semi-unique identifier broadcasted by a device. The method connects the device with the activity tracking device after the semi-unique identifier is found to be of the device by the activity tracking device. The activity tracking device is configured to communicate with the device to obtain device identification (ID) of the device. The method then automatically links the device to the activity tracking device when the device ID of the device matches a copy of the device ID stored in the activity tracking device. In one example, the tracking devices operate as a master and the devices operate as a slave.

Abstract: A system to determine the difficulty in intubating and/or ventilating and/or extubating a subject, the system comprising: an imaging module to acquire image parameters comprising a dynamic image of part of a head or neck of a subject; a parameter extraction module configured to extract at least one dynamic parameter from the image parameters; and a classification module comprising a classification algorithm configured to determine a difficulty to intubate and/or ventilate value based on the at least one dynamic parameter.

Abstract: A sensor includes a sensor array formed on a first side of a substrate and at least one circuit operative to communicate with the sensor array formed on a second side of the substrate. At least one via extends through the substrate to electrically connect the sensor array to the at least one circuit. Placing the at least one circuit on the second side of the substrate allows the sensor array to occupy substantially all of the first side of the substrate.

Abstract: Disclosed is a wearable electronic device including a body portion wearable on a human body, a circuit portion mounted on the body portion, and a sensor portion contacting the human body to measure a bio signal, wherein the sensor portion is detachably coupled to the body portion.