Abstract: Methods and systems are provided for determining fluid responsiveness in the presence of noise. The system may determine an instantaneous value indicative of fluid responsiveness. In some embodiments, the system may determine a difference between an instantaneous value indicative of fluid responsiveness and a previous value indicative of fluid responsiveness, and select an update characteristic based on whether the difference indicates that the fluid responsiveness is increasing or decreasing. In some embodiments, the system may determine a parameter indicative of fluid responsiveness based on the update characteristic and a previously reported value indicative of fluid responsiveness.

Abstract: A method may include receiving, at a processor, a first electromagnetic radiation signal and a second electromagnetic radiation signal from a regional oximetry sensor having two or more detectors and two or more emitters. The method may also include receiving, at the processor, a trigger signal that has a frequency corresponding to a periodic physical activity of a patient. Additionally, the method may include generating, via the processor, one or more ensemble averaged signals based at least in part on the first and second electromagnetic radiation signals and the trigger signal. Further, the method may include calculating, via the processor, a regional oxygen saturation value based at least in part on the one or more ensemble averaged signals and displaying, via a display, the regional oxygen saturation value.

Abstract: A method and apparatus for non-invasively determining a blood oxygen saturation level within an organ of a subject using direct application of a near infrared spectrophotometric sensor is provided. The method includes the steps of: a) transmitting a light signal directly into the subject's organ using the sensor; b) sensing a first intensity of the light signal and a second intensity of the light signal, after the light signal travels a predetermined distance through the organ of the subject; c) determining an attenuation of the light signal along multiple different wavelengths using the sensed first intensity and sensed second intensity; d) determining a difference in attenuation of the light signal between wavelengths; and e) determining the blood oxygen saturation level within the subject's organ using the difference in attenuation between wavelengths.

Abstract: A wearable pulse oximetry device and associated methods are provided. In some embodiments, the device includes at least two light sources having different wavelengths and at least one detector responsive to the different wavelengths. The device also includes a structure adapted to fixate at a distal end of the wearer's ulna bone at a fixated area. The light sources having different wavelengths and the at least one detector are fixed within, or adjacent to, the structure such that when the structure fixates at the fixated area the light sources and the at least one detector are positioned adjacent to the distal end of the ulna, and the at least one detector is positioned to detect light emitted from the at least two light sources.

Abstract: A method is provided for ophthalmic measurements, wherein the amount of a fluorophore is detected in ocular tissue and the obtained fluorescence signals are normalized by per-forming a ratio.

Abstract: An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated with these devices, includes an illuminator providing patterned white light and/or fluorescent stimulus light. The system receives and images light hyperspectrally, in embodiments using a hyperspectral imaging array, and/or using narrowband tunable filters for passing filtered received light to an imager. Embodiments may construct a 3-D surface model from stereo images, and will estimate optical properties of the target using images taken in patterned light or using other approximations obtained from white light exposures. Hyperspectral images taken under stimulus light are displayed as fluorescent images, and corrected for optical properties of tissue to provide quantitative maps of fluorophore concentration. Spectral information from hyperspectral images is processed to provide depth of fluorophore below the tissue surface. Quantitative images of fluorescence at depth are also prepared.

Abstract: Implantable medical devices, systems, methods and kits for transcutaneous insertion of the implantable medical devices are provided.

Abstract: The application relates to a collection assembly (1), in particular for blood samples, comprising a sample container (2) and a closure device (3) which has a closure cap (22) and a pierceable septum (26) held on the closure cap. At its open end (4) delimited by an end face (11), the sample container has a flange (13) and an annular skirt (15), the flange projecting radially beyond a side wall (7). The annular skirt (15) extends axially from a flange end (14) to a closed end (5) of the sample container (2). The sample container (2), the flange (13) and the annular skirt form a one-piece component. Between an outer surface (9) of the side wall (7) and an inner annular skirt surface (16) facing toward this outer surface, there is an approximately tubular free space (17) which is delimited in the axial direction in the region of the open end (4) by the flange (13).

Abstract: Needle assembly (10) for collecting blood or other liquid samples for discharge into a container, the needle assembly (10) comprising: a housing (12), a first needle hub (18) provided by said housing (12), a first hollow needle (20) portion mounted to said first needle hub (18) and extending from said first needle hub (18) in a distal direction, the first needle (20) having a sharpened first needle tip (22), a second needle hub (30) provided by said housing (12), a second hollow needle (32) portion mounted to said second needle hub (30) and extending from said second needle hub (30) in a proximal direction, opposite to said distal direction, wherein a hollow flashback chamber is arranged within the housing between the first needle (20) portion and the second needle (32) portion, wherein the flashback chamber communicates with the inner lumen provided within the first (20) and second (32) hollow needle portion, wherein the housing (12) is formed from transparent material at least in a region close to the flash

Abstract: A system for assessing a mental health disorder in a human subject, the system comprising: a display configured to display a series of natural test images to the subject; an input by which the subject can input a response, following the display of each test image, as to whether or not the test image satisfies a predetermined categorisation criterion; a control processor configured to control the display of the test images by the display, to measure the duration of time from when each test image is initially displayed to when the corresponding response is input by the subject, and to generate a set of response data including the response times in respect of each of the test images; and a data processor configured to process the set of response data and to compare the processed response data with reference data to assess whether or not the subject has, or is likely to develop, the mental health disorder.

Abstract: A standing position evaluation apparatus includes a center-of-gravity position detection unit that detects a head-center-of-gravity position that is a position of a center of gravity of a head of a subject in a standing position projected onto a floor surface and a body-center-of-gravity position that is a position of a center of gravity of a body of the subject in the standing position projected onto the floor surface, and an evaluation unit that evaluates a standing position balance of the subject by using the detected head-center-of-gravity position and the detected body-center-of-gravity position.

Abstract: Embodiments include methods, systems and computer program products for monitoring a user of a helmet for a traumatic brain injury. Aspects include monitoring one or more eyes of the user with a camera embedded in the helmet and analyzing, by a processor, one or more characteristics of the one or more eyes of the user.

Abstract: Embodiments include method, systems and computer program products for monitoring a user for a traumatic brain injury. Aspects include monitoring a speech of the user with a microphone embedded in the helmet and analyzing, by a processor, one or more characteristics of the speech of the user.

Abstract: Embodiments include methods, systems and computer program products for monitoring a person for a traumatic brain injury. Aspects include monitoring a gait of the user with one or more accelerometers embedded in the uniform and analyzing, by a processor, one or more characteristics of the gait of the user. Aspects also include determining whether the one or more characteristics of the gate indicate that the user may have suffered the traumatic brain injury and creating an alert that the user of the helmet may have suffered the traumatic brain injury.

Abstract: The present invention presents methods and apparatus for detecting, imaging, monitoring, and modulating of brain activities and neuronal activities in the brain using radiofrequency (RF) electromagnetic (EM) waves, as well as methods and apparatus for detecting, imaging, and monitoring breathing and heart-beating using RF EM waves.

Abstract: Method of analyzing uterine contractions by analyzing uterine images using deformable model networks in support of embryo transfer techniques. The method is also used to diagnose premature uterine contractile activity in mammals. The method can be used to control contractile activity during embryo transfer or premature labor when used in conjunction with oxytocin antagonists.

Abstract: A method for predicting health compromise in a fetus comprises acquiring one or more EEG signals and a fetal heart rate (FHR) signal from the surface of the head of a fetus; and determining the spectral edge frequency (SEF) of the one or more EEG signals. A repetitive temporal correlation between the FHR signal and the SEF of the one or more EEG signals is indicative of fetal health compromise. A system for detecting the correlation between FHR signal and the SEF of the one or more EEG signals and predicting fetal health compromise is also described.

Abstract: Systems, devices, and methods are described for acquiring, among other things, lesion information from a hair or fur-covered region of a biological subject.

Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.

Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.

Abstract: Embodiments include method, systems and computer program products for monitoring a user for a traumatic brain injury. Aspects include monitoring a speech of the user with a microphone embedded in the helmet and analyzing, by a processor, one or more characteristics of the speech of the user.

Abstract: A hypodermic needle device has disposable and reusable portions. The disposable portion includes a hypodermic needle having a tubular bore, at least one optical imaging waveguide extending along the needle so that a distal end of the optical imaging waveguide is proximate the tip of the needle, and a first coupler for securing the optical imaging waveguide within the needle at the proximal end thereof. A second coupler remote from the first coupler removably secures a proximal end of the optical imaging waveguide to the reusable portion. The reusable portion includes a mating coupler to removably connect to the second coupler and a respective viewing device so that a user can view the image transmitted by the optical imaging waveguide from its distal end to its proximal end. The second coupler contains a lens for imaging an enlarging the image transmitted from the distal end of the optical imaging waveguide.

Abstract: A virtual image display system adapted for venipuncture applications is provided. The virtual image display system includes at least one infrared light source, at least one image sensing module, and at least one virtual image display module. The at least one infrared light source is configured to emit at least one infrared light to a tissue having a vein. The at least one image sensing module is configured to receive the infrared light from the tissue so as to sense an image of the vein. The at least one virtual image display module is disposed in front of at least one eye of a user. The at least one virtual image display module includes an image display unit configured to show an image of the vein to the at least one eye of the user.

Abstract: Provided are a sleeping state detection system and method that can detect the sleeping state of a subject such as an inpatient or a tenant without causing the subject stress, and that can ascertain the health state of the subject from the detection results. The sleeping state detection system includes a room or closed space (201) in which the subject sleeps, and a dust counter (206) that measures the dust particles inside the room or closed space (201). In a state where the inside of the room or closed space (201) is kept cleaner than the outside of the room or closed space (201) by using a fan filter unit (208) disposed in the room or closed space (201), while the subject sleeps, the change over time in the number of dust particles inside the room or closed space (201) is measured using the dust counter (206), and thereby the sleeping state of the subject is detected. The inside of the room or closed space (201) is preferably kept at a cleanliness of US 209D Class100 or better.

Abstract: A method for monitoring anesthetization of a patient, includes the steps of removably connecting a plurality of electrodes to the scalp of the patient and administering sufficient anesthesia to the patient so that the patient attains a plane of anesthesia selected by an operator. The brain waves of the patient are then amplified and digitized after the patient has been anesthetized, before beginning the medical procedure, to obtain a first set of digital data. The brain waves of the patient are then amplified and digitized during the medical procedure to provide a second set of digital data and the first and second sets of digital data are analyzed in at least one of a time domain and a frequency domain. Separate trajectories are then computed from the data analysis trajectories for at least two different indices of an anesthetic state of the patient during the medical procedure, the indices being selected from a group including a Depth Index (DI), a Memory Index (MI) and a Pain Index (PI).

Abstract: Embodiments of the present disclosure relate generally to the use of spectral sensors during a cardiac arrest event. More specifically, the present disclosure relates to the use of spectral sensors for measuring changes in pH and muscle oxygen saturation to estimate subject down time and evaluating the effectiveness of the clinical treatment administered during a cardiac arrest event. Given the narrow window of time in which emergency treatment must be administered, as well as the lack of information concerning the subject's condition, there is a need for a fast and accurate method of estimating the onset of the cardiac arrest emergency and evaluating the effectiveness of the emergency treatment being administered.

Abstract: A system for non-invasively measuring a physiologic status patient tissue according to an embodiment includes a housing; an optical spectroscope with a wavelength-sensitive sensor capable of detecting light intensity, at two or more distinct wavelengths, of light scattered and/or reflected by muscle tissue of the patient in order to measure a physiologic status of the muscle tissue, a bioimpedance sensor at least partially disposed within the housing, the bioimpedance sensor configured to generate a signal corresponding to an estimation of a thickness of an adipose tissue layer between the optical spectroscope and the muscle tissue, and a processor configured to (1) receive the estimations of the thickness, (2) compare the estimations of the thickness, and (3) based on the comparison, generate a visual indication configured to assist in placement of the housing toward or at a location corresponding to the smaller or smallest thickness of the adipose tissue layer.

Abstract: A wearable device measures heart rate recovery of a user in a non-clinical setting. The wearable device comprises a heart rate detector configured to detect heart rate data of the user, an activity sensor configured to detect motion of the user, and a processor. The processor is configured to identify a start of an activity by the user using the motion detected by the activity sensor. Responsive to detecting the start of the activity, the processor monitors the motion detected by the activity sensor to identify an end of the activity. A regression analysis is performed on heart rate data detected by the heart rate detector during a period of time after the end of the activity, and the heart rate recovery of the user is determined using the regression analysis.

Abstract: Physiological monitoring can be provided through a wearable monitor that includes a flexible extended wear electrode patch and a removable reusable monitor recorder. The wearable monitor sits centrally on the patient's chest along the sternum, which significantly improves the ability to sense cutaneously cardiac electric signals, particularly those generated by the atrium. The electrode patch is shaped to fit comfortably and conformal to the contours of the chest approximately centered on the sternal midline. The electrode patch is made from a type of stretchable spunlace fabric. To counter patient bending motions and prevent disadhesion of the electrode patch, the outward-facing aspect of the backing, to which a (non-stretchable) flexible circuit is fixedly attached, stretches at a different rate than the backing's skin-facing aspect, where a skin adhesive removably affixes the electrode patch to the skin.

Abstract: A physiological signal monitoring belt includes a belt-shaped unit and an electrode unit. The electrode unit is disposed on a surface of the belt-shaped unit and includes a base layer, an intermediate layer, and a conductive layer. The intermediate layer has a first surface and a second surface. The base layer is disposed on the first surface, and the conductive layer is disposed on the second surface. The electrode unit is disposed on the surface of the belt-shaped unit through the base layer.

Abstract: Techniques associated with a wearable device structure with enhanced motion detection by a motion sensor are described, including a band configured to be worn, a nodule coupled to the band, the nodule including a structure configured to enhance detection of movement of an adjacent skin surface, the structure having an articulator configured to rotate in a plurality of planes, and a sensor coupled to the structure and configured to detect rotational motion.

Abstract: A biometric information detecting apparatus includes a bio-signal measurer including a light-emitting unit and a light-receiving unit, the light-emitting unit configured to emit an optical signal and the light-receiving unit configured to detect the optical signal that is modulated by a target object; a low-frequency signal obtainer configured to obtain a low-frequency signal from the bio-signal measured by the bio-signal measurer; and a signal processor configured to analyze biometric information from the bio-signal in response to determining that the low-frequency signal obtained from the bio-signal is within a reference range.

Abstract: Disclosed are an electronic device and method for controlling the same. According to the present invention, an electronic device and method for controlling the same include a body, a plurality of electrodes exposed to a surface of the body to contact at least two portions of a user's body, and a controller configured to apply a current to at least any one of the plurality of electrodes to obtain a bio signal of the user. According to the present invention, the user's bio signal may be obtained.

Abstract: A life watching and support apparatus is connected to a living behavior acquirement apparatus configured to acquire behavior information of a user, to a physiological information acquirement apparatus configured to acquire physiological information of the user, and to a display apparatus on a watcher side watching the user. The life watching and support apparatus includes a behavior estimation section configured to estimate a living behavior situation of the user based on the behavior information of the user, a health condition determination section configured to determine a health condition of the user based on the estimated living behavior situation and the physiological information, and an output control section configured to display a watching screen including the determined health condition in the display apparatus on the watcher side depending on the health condition.

Abstract: A device used to establish a contact between a subject and a measuring device using measurement technology, wherein the subject can be a patient. The device has at least one measuring device for connecting to the subject and at least one line to which the measuring device is secured. The line is designed such that the measured variables detected by the measuring device can be conducted to a measuring unit. A mat is connected to the at least one line so as to at least partly form an internal line section.

Abstract: A biological parameter of a subject is estimated, which is present on a support, the support comprising at least two sensors each measuring a variation of pressure, wherein at least one accelerometer is connected to the support. A sensor-specific model is provided for each of the at least two sensors based on signals from the at least two sensors, the signals corresponding to the variation of pressure measured by the at least two sensors, respectively. In a selection process, at every time frame T, one sensor is selected out of the at least two sensors, to be used for estimating the biological parameter of the subject, based on signals from the at least one accelerometer. In an estimation process, the biological parameter of the subject is estimated using, at every time frame T, the sensor-specific model provided for the selected one sensor.

Abstract: The invention relates to a piezoresistive textile sensor for detecting the heart and respiratory rate, comprising a lower textile layer whereon a conductive ink or paste is deposited such that first conductive strips are defined, said lower textile layer being joined to a second piezoresistive textile layer whereon a second conductive strip is arranged, to which an upper textile layer is then joined, on which conductive inks and/or pastes can be deposited, said piezoresistive textile sensor being used in a system for detecting the heart and/or respiratory rate.

Abstract: Physiological measuring instruments can detect and produce an electrophysiological signal from the physiological response of a biological subject (e.g., a human, an animal, or the like) to stimulus. For example, an electrode in electrical contact with an eye of a human or an animal can detect and produce an electrophysiological signal from the biological response of the eye to light stimulus. One or more noise components in the electrophysiological signal can be reduced by estimating the noise component(s) and then subtracting the estimated noise component(s) from the detected electrophysiological signal.

Abstract: Cardiac artifacts can be removed from respiration waveforms by receiving a stream of respiration samples of a sensed respiration signal that collectively characterize respiration data for a patient. In addition, heart rate data is received that specifies a heart rate for the patient that is measured concurrently with the sensed respiration signal. Each respiration sample in the stream is continuously and adaptively filtered to result in a corresponding filtered respiration signal that removes cardiac artifacts. This filtering subtracts an earlier respiration sample having a delay equal to a period corresponding to the heart rate of the patient from the then current respiration sample. The filtered respiration signals can then be promoted. Related apparatus, systems, techniques, and articles are also described.

Abstract: The living body information sensor according to the present invention can be attached to a living body. A light emitting unit emits light to the living body. The light receiving unit receives reflected light from the living body that is included in the light emitted by the light emitting unit to the living body, and outputs a signal according to intensity of the reflected light. A control device generates information about the living body based on the signal from the light receiving unit. The control device controls the light emitting unit to turn on and off in an alternate manner. The control device sets a total of a turn-on time of the light emitting unit in a prescribed time interval to be smaller when the living body information sensor is attached to the living body than when the living body information sensor is not attached to the living body.

Abstract: The present invention relates to a method for compressing signal data of a plurality of biological signals captured by a plurality of implanted measurement devices. The present invention further relates to an implantable sensor configured to carry out said method of compression. The present invention also concerns a method for recovering the plurality of biological signals from the compressed data as well as a system including a plurality of implantable sensors, a transmitter, a receiver and a processor configured to recover the plurality of biological signals from the compressed data.

Abstract: Systems and methods of optimal pulse compression are described. A pulse compression system can include an operations component that can receive a first signal, transmit the signal toward a target, and receive a reflected signal. A processor can correlate the received signal with an optimized signal in order to generate an image, the optimized signal based on an impulse response function of the operations component. The optimized signal can be the first signal. The optimized signal can be a third signal separate from the first signal.

Abstract: The present invention provides for three-dimensional reflectance diffuse optical imaging of deep tissue blood flow distribution that removes the need for probe-tissue contact, thereby allowing for such technology to be applied to sensitive, vulnerable, damaged, or reconstructive tissue. The systems utilize noncontact application and detection of near-infrared light through optical lens and detection through a linear array or two-dimensional array of avalanche photodiodes or a two-dimensional array of detectors provided by charge-coupled-device (CCD). Both further feature a finite-element-method (FEM) based facilitation to provide for three-dimensional flow image reconstruction in deep tissues with arbitrary geometries.

Abstract: The invention provides methods and kits for detecting, screening, quantifying or localizing the etiology for reduced or impaired cranial nerve function or conduction; localizing a central nervous system lesion; detecting, diagnosing or screening for increased intracranial pressure, pressure or disruption of central nervous system physiology as seen with concussion; or detecting, diagnosing, monitoring progression of or screening for a disease or condition featuring increased intracranial pressure or concussion by tracking eye movement of the subject.

Abstract: Embodiments of the disclosure are directed to apparatuses, methods and computer program products for determining cardiac output. An exemplary method comprises: receiving blood pressure data; determining a standard deviation associated with the blood pressure data; determining a pulse rate associated with the blood pressure data; determining a compliance factor associated with the blood pressure data; determining a function associated with the blood pressure data; and determining the cardiac output based on the standard deviation, the pulse rate, the compliance, and the function.

Abstract: A blood flow image diagnosing device of the present invention includes a laser light irradiation system for applying laser light to an observation region of a biotissue having blood cells; a light receiving section having a plurality of pixels and adapted to detect reflection light from the observation region of the biotissue; an image capturing section for successively capturing a plurality of images on the basis of a signal from the light receiving section; an image storage section for storing the plurality of images; a computation section for computing the speed of blood flow within the biotissue from time course changes of output signals of the pixels throughout the stored images; and a display section for displaying a two-dimensional distribution which is the result of the computation as a blood flow map.

Abstract: Cone-beam computer tomography systems, devices, and methods for image acquisition of large target volumes using partial scans.

Abstract: A radiographic system provide a simple operation for table movement where the table revolves in one direction in accordance with an input of a revolving direction from a console driving the table upward vertically when one end of the table come close to a floor surface. The present invention also includes a system where the table moves downward vertically automatically, interlocking with a revolving of the table when the revolving direction is input to the revolving direction input means. According to the present invention, the table lifted along with revolving can be revolved or moved upward with an input operation in one system. Therefore, the operation of the radiographic apparatus can be easy.

Abstract: Disclosed herein is a method and apparatus for operating an X-ray image processing system of creating a panoramic image based on three-dimensional (3D) Computed Tomography (CT) image data and displaying the panoramic image on the display unit, receiving a part of an object to be measured in the panoramic image through the input unit, and calculating an actual 3D length of the part of the object based on depth information of the CT image data and displaying the actual 3D length on the display unit. The part of the object can be selected by the user to measure a length of a desired part.

Abstract: In a radiation imaging system, which obtains a radiation image of an object based on a plurality of image signals, includes a radiation imaging apparatus, which includes a plurality of pixels arranged in a two-dimensional matrix, configured to convert an irradiated radiation transmitted through an object into an image signal serving as a partial image of the object. In the radiation imaging system, a holding unit for holding the radiation imaging apparatus holds the radiation imaging apparatus to be movable in a direction intersecting a direction in which positions to obtain a plurality of partial images are arranged.