Patents Issued in October 25, 2016
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Patent number: 9475876Abstract: A monoclonal antibody against oncostatin M specific receptor beta subunit, a hybridoma capable of producing the same and a medicament for treating atopic dermatitis comprising the same.Type: GrantFiled: May 10, 2013Date of Patent: October 25, 2016Assignees: Wakayama Medical University, SBI Biotech Co., Ltd.Inventors: Yoshihiro Morikawa, Tadasuke Komori, Eiji Esashi, Ayumi Kotaki
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Patent number: 9475877Abstract: The present invention relates to amino acid sequences that are directed against RANK-L, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and polypeptides; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.Type: GrantFiled: September 11, 2009Date of Patent: October 25, 2016Assignee: Ablynx N.V.Inventors: Els Anna Alice Beirnaert, Sigrid Cornelis, Hendricus Renerus Jacobus Mattheus Hoogenboom
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Patent number: 9475878Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.Type: GrantFiled: August 31, 2012Date of Patent: October 25, 2016Assignees: KYOWA HAKKO KIRIN CO., LTD, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGYInventors: Shinichiro Kato, Rachel Soloff Nugent, Hitoshi Yoshida, Michael Croft
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Patent number: 9475879Abstract: Antibody polypeptides that specifically bind a novel epitope of human CD40 are provided. The antibody polypeptides do not exhibit CD40 agonist activity. The antibody polypeptides are useful in the treatment of diseases involving CD40 activation, such as autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VL or VH domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA).Type: GrantFiled: April 20, 2012Date of Patent: October 25, 2016Assignees: BRISTOL-MYERS SQUIBB COMPANY, DOMANTIS LIMITEDInventors: Anish Suri, Steven Sheriff, Suzanne Suchard, Aaron Yamniuk, Stanley Krystek, James Tamura, James Bryson, Steven Grant, Philip Drew
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Patent number: 9475880Abstract: The invention provides antibodies that specifically bind to human CD134. Invention anti-human CD134 antibodies specifically bind to the extracellular domain of human CD134, including non-OX40 ligand (OX40L) binding domains on human CD134, which is expressed on e.g. activated human conventional effector CD4 and/or CD8 T lymphocytes (Teffs) and on activated human suppressive regulatory CD4 T lymphocytes (Tregs). Invention anti-human CD134 antibodies are useful (e.g. to empower Teffs anti-cancer effector function and/or to inhibit Tregs suppressive function) for cancer treatment.Type: GrantFiled: September 13, 2012Date of Patent: October 25, 2016Assignees: Biocerox Products, B.V., Janssen Pharmaceuticals, Inc.Inventors: Petrus Johannes Simons, Louis Boon
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Patent number: 9475881Abstract: The present invention relates to novel Fc variants that comprise at least one novel amino acid residue which may provide for enhanced effector function. More specifically, this invention provides Fc variants that have modified binding affinity to one or more Fc receptor or ligand (e.g., Fc gamma R, C1q). Additionally, the Fc variants have altered complement dependent cytotoxicity (CDC) activity and/or antibody-dependent cell-mediated cytotoxicity (ADCC). The invention further provides methods and protocols for the application of said Fc variants, particularly for therapeutic purposes.Type: GrantFiled: January 22, 2013Date of Patent: October 25, 2016Assignee: Xencor, Inc.Inventors: Gregory A. Lazar, Sher Bahadur Karki, Gregory L. Moore
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Patent number: 9475882Abstract: Provided herein is technology relating to antagonists that inhibit, reduce, or minimize the interaction of integrin associated protein (IAP) with Src homology 2 (SH2) domain-containing protein tyrosine phosphatase substrate 1 (SHPS1) and particularly, but not exclusively, to compositions comprising such antagonists and methods of treatment comprising administering such antagonists.Type: GrantFiled: November 8, 2013Date of Patent: October 25, 2016Assignee: The University of North Carolina at Chapel HillInventors: David R. Clemmons, Laura A. Maile
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Patent number: 9475883Abstract: Disclosed are methods and compositions of anti-B cell antibodies, preferably anti-CD22 antibodies, for diagnosis, prognosis and therapy of B-cell associated diseases, such as B-cell malignancies, autoimmune disease and immune dysfunction disease. In certain embodiments, trogocytosis induced by anti-B cell antibodies may determine antibody efficacy, disease responsiveness and prognosis of therapeutic intervention. In other embodiments, optimal dosages of therapeutic antibody may be selected by monitoring the degree of trogocytosis induced by anti-B cell antibodies.Type: GrantFiled: October 15, 2015Date of Patent: October 25, 2016Assignee: Immunomedics, Inc.Inventors: Chien-Hsing Chang, David M. Goldenberg, Hans J. Hansen, Edmund A. Rossi
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Patent number: 9475884Abstract: The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy.Type: GrantFiled: March 26, 2015Date of Patent: October 25, 2016Assignee: Immunomedics, Inc.Inventors: Serengulam V. Govindan, David M. Goldenberg
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Patent number: 9475885Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.Type: GrantFiled: March 17, 2015Date of Patent: October 25, 2016Assignee: Omeros CorporationInventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
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Patent number: 9475886Abstract: The present invention relates to a recombinant antibody composition having higher complement-dependent cytotoxic activity than a human IgG1 antibody and a human IgG3 antibody, wherein a polypeptide comprising a CH2 domain in the Fc region of a human IgG1 antibody is replaced by a polypeptide comprising an amino acid sequence which corresponds to the same position of a human IgG3 antibody indicated by the EU index as in Kabat, et al.; a DNA encoding the antibody molecule or a heavy chain constant region of the antibody molecule contained in the recombinant antibody composition; a transformant obtainable by introducing the recombinant vector into a host cell; a process for producing the recombinant antibody composition using the transformant; and a medicament comprising the recombinant antibody composition as an active ingredient.Type: GrantFiled: September 30, 2014Date of Patent: October 25, 2016Assignee: KYOWA HAKKO KIRIN CO., LTD.Inventors: Kenya Shitara, Rinpei Niwa, Akito Natsume
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Patent number: 9475887Abstract: A novel compound is disclosed, said compound comprising hyaluronic acid, optionally cross-linked, or an oligomer, optionally cross-linked, dimer or monomer thereof, which is salified or at least partially salified with carnosine, wherein the carnosine is in the form of an L- or D-enantiomer or a racemate; a process for producing this compound, its cosmetic and therapeutic use as well as pharmaceutical and cosmetic compositions containing the same are also disclosed.Type: GrantFiled: December 6, 2011Date of Patent: October 25, 2016Inventor: Gianfranco De Paoli Ambrosi
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Non anti-coagulative glycosaminoglycans comprising repeating disaccharide unit and their medical use
Patent number: 9475888Abstract: The present invention relates to a chemically modified glycosaminoglycan with an antifactor II activity of less than 10 IU/mg, an antifactor Xa activity of less than 10 IU/mg and an average molecular weight (Mw, weight average) from about 4.6 to 6.9 kDa. Also disclosed is a method of preparing the modified glycosaminoglycan and its medical uses.Type: GrantFiled: December 19, 2012Date of Patent: October 25, 2016Assignee: Dilafor ABInventors: Hans-Peter Ekre, Ulf Lindahl, Erik Holmer, Per-Olov Eriksson -
Patent number: 9475889Abstract: The photocuring efficiency of an N-oxyazinium salt photoinitiator is increased by mixing it with an organic phosphine as a photoinitiator efficiency amplifier, and with an aryl aldehyde or alkyl aldehyde having a molecular weight of less than 1000. This mixture or photoinitiator composition can be used to cure acrylates or other photocurable compounds, particularly in an oxygen-containing environment.Type: GrantFiled: January 7, 2015Date of Patent: October 25, 2016Assignee: EASTMAN KODAK COMPANYInventor: Deepak Shukla
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Patent number: 9475890Abstract: A catalyst comprising (i) a metallocene complex of a group (IV) metal said metallocene comprising at least two cyclopentadienyl type ligands; (ii) a boron cocatalyst; and (iii) an aluminoxane cocatalyst; said catalyst being in solid form, preferably in solid particulate form, and being free from an external carrier.Type: GrantFiled: October 17, 2013Date of Patent: October 25, 2016Assignee: Borealis AGInventors: Kalle Kallio, Marja Mustonen, Lauri Huhtanen, John Severn, Pascal Castro, Ville Virkkunen, Anu-Leena Hongell, Ismo Lehtiniemi
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Patent number: 9475891Abstract: A novel process of manufacturing colesevelam hydrochloride including the steps of alkylating polyallylamine with n-decylbromide and 6-bromohexyl trimethyl ammonium bromide, followed by cross-linking the alkylated polyallylamine with epichlorohydrin in an aqueous medium, and adding a suitable chloride ion source to obtain colesevelam hydrochloride.Type: GrantFiled: September 18, 2014Date of Patent: October 25, 2016Assignee: Navinta, LLCInventor: Mahendra R. Patel
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Patent number: 9475892Abstract: Process for the continuous transition between two different and compatible polymerization catalysts.Type: GrantFiled: April 13, 2011Date of Patent: October 25, 2016Assignee: INEOS SALES (UK) LIMITEDInventors: Jean-Louis Chamayou, Benoit Sibourd
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Patent number: 9475893Abstract: A supported catalyst system may include a titanated silica-containing catalyst support having at least 0.1 wt % of Ti and a specific surface area of from 150 m2/g to 800 m2/g. The Ti may be of a titanium compound of the general formula selected from RnTi(OR?)m, and (RO)nTi(OR?)m, wherein R and R? are the same or different and are selected from hydrocarbyl groups containing from 1 to 12 carbons or halogens, wherein n is 0 to 4, wherein m is 0 to 4, and wherein m+n equals 4. The supported catalyst system may include a catalyst activating agent and a metallocene. The supported catalyst system may be obtained by a process including titanating a silica-containing catalyst support with at least one vaporized titanium compound, and treating the titanated silica-containing catalyst support with a catalyst activating agent and a metallocene.Type: GrantFiled: May 11, 2015Date of Patent: October 25, 2016Assignee: Total Research & Technology FeluyInventors: Christopher Willocq, Martine Slawinski, Aurélien Vantomme
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Patent number: 9475894Abstract: A dendritic polymer, a dendritic polymer monomer, and a hyperbranched copolymer are described. The dendritic polymer monomer has a structure denoted by Z?-(Q)n-Y, wherein Z? represents a structure denoted by the following formula (a) and/or formula (b), Q represents a dendritic constitutional repeating unit of the dendritic polymer monomer, n represents the generation number of the dendritic polymer monomer, and is an integer within a range of 2-6, Y represents a group that contains SO3? or COO?, R14-R16 can be identical to or different from each other, and are H or C1-C5 alkyl respectively. The monomer can be used as a copolymerizable monomer for preparing a hyperbranched polymer applicable to oil fields, the obtained hyperbranched polymer can be used as an inhibiting filtrate reducer for drilling fluid, flocculating agent, encapsulating agent, heat-resistant and salinity-resistant polymer flooding agent, and thickening agent for fracturing liquid, etc.Type: GrantFiled: June 25, 2014Date of Patent: October 25, 2016Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC ZHONGYUAN OILFIELD SERVICE CORPORATION DRILLING ENGINEERING RESEARCH INSTITUTEInventor: Zhonghua Wang
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Patent number: 9475895Abstract: An object of the invention is to provide a sulfur-modified chloroprene rubber composition improved in heat resistance. A sulfur-modified chloroprene rubber composition, comprising a sulfur-modified chloroprene rubber containing sulfur chemically bound thereto and sulfur not chemically bound to the sulfur-modified chloroprene rubber, wherein: the ratio of the amount of sulfur chemically bound to the sulfur-modified chloroprene rubber to the total amount of sulfur in the sulfur-modified chloroprene rubber composition (amount of chemically bound sulfur [mass %]/total amount of sulfur [mass %]) is 0.1 to 0.45; and the sulfur-modified chloroprene rubber has, at the molecular terminal, at least one structure represented by the following General Formula (1) or (2): —S—C(?S)—O—R1 . . . (1) (in General Formula (1), R1 represents an alkyl group having 1 to 4 carbon atoms) or —S—R2 . . . (2) (in General Formula (2), R2 represents an alkyl group having 8 to 20 carbon atoms).Type: GrantFiled: September 10, 2013Date of Patent: October 25, 2016Assignee: DENKA COMPANY LIMITEDInventors: Takashi Sunada, Yasushi Abe, Naoki Kobayashi
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Patent number: 9475896Abstract: Method for preparing olefin polymer in a loop reactor, said loop reactor comprises a first outlet for withdrawing polymer slurry from the loop reactor, and a second outlet for withdrawing a polymer slurry from the loop reactor, wherein the first outlet is located such that polymer slurry is withdrawn having a concentration of polymer which is equal or higher than the average concentration of polymer in the loop reactor, and the second outlet is located such that polymer slurry is withdrawn having a concentration of polymer which is lower than the average concentration of polymer in the loop reactor, the method comprises the steps of supplying olefin monomers and a catalytic system to the loop reactor to form a polymer slurry in the loop reactor, and controlling the total amount of polymer and/or the total amount of polymer slurry withdrawn from the loop reactor by adjusting the ratio of polymer slurry withdrawn through the first outlet and polymer slurry withdrawn through the second outlet.Type: GrantFiled: December 12, 2012Date of Patent: October 25, 2016Assignee: Borealis AGInventors: Pauli Leskinen, Sameli Hakola, Kauno Alastalo, Klaus Nyfors
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Patent number: 9475897Abstract: Process for the preparation of (co)polymers of conjugated dienes which comprises polymerizing at least one conjugated diene in the presence of a catalytic system comprising at least one bis-imino-pyridine complex of cobalt having general formula (I): wherein: R2 and R3, equal to or different from each other, represent a hydrogen atom; or they are selected from linear or branched C1-C20 preferably C1-C15, alkyl groups, optionally halogenated, cycloalkyl groups optionally substituted, aryl groups optionally substituted; R1 and R4, different from each other, represent a hydrogen atom; or they are selected from linear or branched C1-C20 preferably C1-C15, alkyl groups, optionally halogenated, cycloalkyl groups optionally substituted, aryl groups optionally substituted; arylalkyl groups; or R1 and R2 can be optionally bound to each other to form, together with the other atoms to which they are bound, a cycle containing from 3 to 6 carbon atoms, saturated, unsaturated, or aromatic, optionally substituted with lineaType: GrantFiled: December 20, 2013Date of Patent: October 25, 2016Assignee: Versalis S.P.A.Inventors: Francesco Masi, Giovanni Ricci, Anna Sommazzi, Giuseppe Leone, Maria Caldararo
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Patent number: 9475898Abstract: Disclosed herein are ethylene-based polymers having a higher molecular weight component and a lower molecular weight component, and characterized by a density greater than 0.945 g/cm3, a melt index less than 1.5 g/10 min, and a ratio of high load melt index to melt index ranging from 40 to 175. These polymers have the processability of chromium-based resins, but with improved stiffness and stress crack resistance, and can be used in blow molding and other end-use applications.Type: GrantFiled: September 21, 2015Date of Patent: October 25, 2016Assignee: Chevron Phillips Chemical Company LPInventors: Vivek Rohatgi, Jeffrey F. Greco, Yongwoo Inn, Qing Yang, Alfred E. Brown, Jr.
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Patent number: 9475899Abstract: The present invention pertains to a process for manufacturing a solid composite layer, said process comprising the following steps: (i) providing a mixture comprising: at least one functional fluoropolymer comprising at least one hydroxyl group [polymer (F)], at least one metal compound of formula (I) [compound (M)]: X4-mAYm wherein X is a hydrocarbon group, optionally comprising one or more functional groups, m is an integer from 1 to 4, A is a metal selected from the group consisting of Si, Ti and Zr, and Y is a hydrolysable group selected from the group consisting of an alkoxy group, an acyloxy group and a hydroxyl group, and at least one inorganic filler material [filler (I)] in an amount of from 50% to 95% by weight, with respect to the total weight of said polymer (F) and said filler (I); (ii) reacting at least a fraction of said hydroxyl group(s) of at least one polymer (F) with at least a fraction of said hydrolysable group(s) Y of at least one compound (M), so as to provide a fluoropolymer comType: GrantFiled: December 5, 2013Date of Patent: October 25, 2016Assignee: SOLVAY SPECIALTY POLYMERSInventors: Marco Miele, Julio A. Abusleme, Ricardo Pieri
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Patent number: 9475900Abstract: The present invention provides a drilling fluid additive comprising a specific cation-modified PVA-based resin and a drilling fluid containing the same. The drilling fluid additive can reduce hydration swelling of inorganic clay mineral such as bentonite, and provide a drilling fluid such as drilling mud capable of forming a thin and tough mud wall on the stratum during drilling operation.Type: GrantFiled: December 11, 2013Date of Patent: October 25, 2016Assignee: THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD.Inventors: Masahiro Saito, Midori Asai
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Patent number: 9475901Abstract: The present disclosure provides for new photoalignment (co)polymer materials which demonstrate improved adhesion to a substrate. The (co)polymeric structure includes at least one photochemically active chromophore and at least one adhesion promoter group. Articles of manufacture, optical elements, ophthalmic elements and liquid crystal cells which include at least one photoalignment layer made from the photoalignment (co)polymer materials and methods for formation are also disclosed.Type: GrantFiled: December 3, 2010Date of Patent: October 25, 2016Assignee: Transitions Optical, Inc.Inventors: Gobinda Saha, Anil Kumar
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Patent number: 9475902Abstract: The present invention relates to polymers functionalized by terminal groups, where the polymers have a trialkylsilyloxy group of the formula (I) at the end of the chain, where R1, R2, and R3 can be identical or different and are alkyl, cycloalkyl, and aralkyl moieties which can comprise heteroatoms such as O, N, S, and Si.Type: GrantFiled: November 11, 2011Date of Patent: October 25, 2016Assignee: ARLANXEO Deutschland GmbHInventor: Norbert Steinhauser
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Patent number: 9475903Abstract: 1,4-bis(isocyanatomethyl)cyclohexane contains 70 mol % or more and 95 mol % or less of a trans isomer relative to a total amount of a cis isomer and the trans isomer, and 0.Type: GrantFiled: September 25, 2014Date of Patent: October 25, 2016Assignee: MITSUI CHEMICALS, INC.Inventors: Satoshi Yamasaki, Hirokazu Morita, Goro Kuwamura, Daisuke Nishiguchi, Toshihiko Nakagawa, Daisuke Hasegawa, Tetsuya Hamada, Shinji Kiyono, Takeshi Fukuda, Kazuhiro Kosumi, Hidetaka Tsukada, Kenichi Goto, Shinsuke Ito, Naoyuki Kakinuma
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Patent number: 9475904Abstract: Heat-curable epoxy resin compositions and the use thereof, for example, in motor vehicle construction and sandwich panel construction, are disclosed. Exemplary heat-curable epoxy resin compositions include, in addition to epoxy resin components A1, optionally A2, a hardener component B, a carboxylic acid C and a hydroxyalkylamide or hydroxyalkylurea H, an accelerator E for activation of the conversion of components A1, A2 and B. The compositions and the structural foams produced therefrom are notable for high mechanical strength, high glass strength and good adhesion capacity on metallic and nonmetallic substrates, and it is possible at the same time to dispense with the use of toxic or inflammable blowing agents.Type: GrantFiled: September 2, 2011Date of Patent: October 25, 2016Assignee: SIKA TECHNOLOGY AGInventors: Jürgen Finter, Elyes Jendoubi
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Patent number: 9475905Abstract: An aliphatic polycarbonate is disclosed in which a salt consisting of a metal or onium cation and an anion having a pKa not greater than 3 is dispersed. The aliphatic polycarbonate includes repeating units of Formula 1: [-A-OC(O)O-] (wherein A is a substituted or unsubstituted C3-C60 alkylene, or a substituted or unsubstituted C3-C60 heteroalkylene and the O-A-O units in one polymer chain may be identical to or different from each other).Type: GrantFiled: May 28, 2013Date of Patent: October 25, 2016Assignee: LOTTE CHEMICAL CORPORATIONInventors: Bun Yeoul Lee, Ji Hae Park, Jong Yeob Jeon, Jung Jae Lee, Young Eun Jang
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Patent number: 9475906Abstract: The present invention relates to an arc-extinguishing insulation material molded product provided in the vicinity of a contact point between contactors in a gas circuit breaker. The arc-extinguishing insulation material molded product includes a polymer which contains a carbon-oxygen bond in the main chain, and in which a part of or all of terminal atoms are non-hydrogen atoms.Type: GrantFiled: September 11, 2013Date of Patent: October 25, 2016Assignee: Mitsubishi Electric CorporationInventors: Kazuki Kubo, Tatsuya Okawa, Katsuhiko Horinouchi, Motohiro Sato
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Patent number: 9475907Abstract: The present invention relates to a method for the preparation of polyquaternium-1, wherein an aprotic polar solvent is used as the reaction medium, and a solid polyquaternium-1 having a low degree of polydispersity.Type: GrantFiled: June 19, 2013Date of Patent: October 25, 2016Assignee: Alfred E. Tiefenbacher GmbH & Co., KGInventors: Stefan Becker, Uwe Eilitz, Gunnar Göthe, Jens Flemming
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Patent number: 9475908Abstract: The present invention aims to provide an industrially advantageous method for producing an aqueous dispersion of pseudopolyrotaxane enabling to produce an aqueous dispersion of pseudopolyrotaxane having good fluidity and excellent dispersion stability of the pseudopolyrotaxane particles therein. The present invention relates to a method for producing an aqueous dispersion of pseudopolyrotaxane. The method includes: a mixing step of a dissolving polyethylene glycol and a cyclodextrin in an aqueous medium to prepare a mixed solution; and a cooling step of continuously or intermittently cooling the mixed solution in a state of flux to precipitate pseudopolyrotaxane particles. The pseudopolyrotaxane particles contain the polyethylene glycol which is included in the cavities of the cyclodextrin molecules in a skewered manner.Type: GrantFiled: December 5, 2011Date of Patent: October 25, 2016Assignees: Sumitomo Seika Chemicals Co., Ltd., Advanced Softmaterials Inc.Inventors: Tomoaki Yamasaki, Shinya Okazaki, Hiroki Okazaki, Shigeki Hamamoto, Changming Zhao
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Patent number: 9475909Abstract: TASK It is an object of the present invention to provide a hydrogel having excellent mechanical properties and capable of being produced simply by using and mixing an industrially easily obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. MEANS OF SOLVING THE PROBLEM A hydrogel-forming composition is characterized by containing a polyelectrolyte (A), clay particles (B), and a dispersant (C) for the clay particles.Type: GrantFiled: January 8, 2015Date of Patent: October 25, 2016Assignee: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITYInventors: Hiroyuki Takeno, Wataru Nakamura
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Patent number: 9475910Abstract: This disclosure is directed to nanocomposite compositions that are suitable for air bladders, innertubes, innerliners and other desirable air-retention articles. In particular, this disclosure is directed to compositions that include the nanocomposite, the nanocomposite made in such that its air-retention properties are much improved over what is known, while maintaining desirable elasticity and processability. In a particular aspect, an air-retention article such as an innerliner if formed by first contacting a desirable elastomer, especially a functionalized poly(isobutylene-co-p-methylstyrene) elastomer, with one or more layered fillers such as a clay described further below, and also contacting one or more processing aids, and one or more solvents to form an nanocomposite composition.Type: GrantFiled: October 26, 2009Date of Patent: October 25, 2016Assignee: ExxonMobil Chemical Patents Inc.Inventors: Weiqing Weng, Bharat Bhushan Sharma, Michael Brendan Rodgers
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Patent number: 9475911Abstract: The present invention is a polyester composition for a film, wherein the polyester composition comprises a masterbatch polyester composition including 1.0 to 2.0%, by mass of inorganic particles having an average particle diameter of 0.5 to 3.0 ?m and having been prepared using a polycondensation catalyst containing, and an inorganic particle-free polyester resin in a mass ratio of 1:15 to 35; and wherein the polyester composition will cause little filter clogging and can provide a polyester film that is excellent in slipping properties, running properties and wear resistance and will suffer from little deterioration in quality due to defects or insoluble particles located on the film.Type: GrantFiled: March 21, 2013Date of Patent: October 25, 2016Assignee: TOYOBO CO., LTD.Inventors: Satoru Nakagawa, Hideto Ohashi, Kunihiro Maeda
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Patent number: 9475912Abstract: This application discloses a method of photomechanically manipulating optically fixable SMPs that employ glassy, photoresponsive polymeric materials, which are capable of rapid optical-fixing with short exposures (<<5 min) of eye-safe visible light. Key to the optical fixing is the use of polymeric materials composed of covalently attached photochromic units such as azobenzene and the use of light capable of inducing simultaneous trans-cis and cis-trans isomerization of azobenzene or other photochromic moieties capable of similar cycling. Upon exposure to light in this wavelength regime (440-514 nm for the azobenzene unit here), real and lasting reconfigurations are induced capable of fixing both the optically induced strain as well as mechanically induced strain. A linear dependence of bending angle on polarization angle is observed and may be used to control the shape reconfiguration of the SMPs.Type: GrantFiled: August 24, 2015Date of Patent: October 25, 2016Assignee: The United States of America, as represented by the Secretary of the Air ForceInventors: Timothy J. White, Kyung Min Lee
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Patent number: 9475913Abstract: Disclosed is a foam sheet using polylactic acid, which provides the advantages of energy reduction and greenhouse gas reduction, and does not emit toxic substances such as toxic gas or endocrine-disrupting chemicals. The foam sheet, according to the present invention, comprises at least one resin layer comprising a biodegradable resin composition including the polylactic acid having an extended chain, a plasticizer, and a foaming agent, and thus provides the advantages of superior processing properties, superior water resistance after processing, energy reduction and greenhouse gas reduction, and of not emitting toxic substances such as toxic gas or endocrine-disrupting chemicals.Type: GrantFiled: December 27, 2012Date of Patent: October 25, 2016Assignee: LG HAUSYS, LTD.Inventors: Cheng Zhe Huang, Chang Won Kang, Ji Hyang Son
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Patent number: 9475914Abstract: The present invention generally relates to porous polymer monoliths. The present invention also relates to processes for the preparation of porous polymer monoliths, storage mediums formed from porous polymer monoliths and use thereof in the drying and storage of body fluids including blood and blood plasma samples.Type: GrantFiled: January 6, 2011Date of Patent: October 25, 2016Assignee: UNIVERSITY OF TASMANIAInventors: Paul Raymond Haddad, Emily Frances Hilder, Esme Candish, Mark A. J Bayliss
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Patent number: 9475915Abstract: TASK It is an object of the present invention to provide a hydrogel having excellent mechanical properties and capable of being produced simply by using and mixing an industrially easily obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. MEANS OF SOLVING THE PROBLEM A hydrogel-forming composition is characterized by containing a polyelectrolyte (A), clay particles (B), and a dispersant (C) for the clay particles.Type: GrantFiled: January 8, 2015Date of Patent: October 25, 2016Assignee: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITYInventors: Hiroyuki Takeno, Wataru Nakamura
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Patent number: 9475916Abstract: The present invention relates to a method for coating surfaces by applying an oxidatively drying coating composition comprising at least one oxidatively drying binder and at least one drying agent acting as an accelerator of the drying and curing process proceeding under the action of an oxidizing agent, characterized in that the drying agent comprises at least one oxidoreductase and at least one mediator which is converted by the at least one oxidoreductase.Type: GrantFiled: October 18, 2013Date of Patent: October 25, 2016Assignee: ALLNEX AUSTRIA GMBHInventors: Roland Feola, Thomas Schonbacher, Armin Temel, Edmund Urbano, Oliver Ferk, Georg Gubitz, Enrique Herrero Acero, Katrin Greimel, Veronika Perz, Amra Suljanovic
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Patent number: 9475917Abstract: A rubber composition and a method for manufacturing the same are provided. The rubber composition includes a main chain modified conjugated diene based polymer and a stabilizer. A weight ratio of the main chain modified conjugated diene based polymer to the stabilizer is 100:0.2˜2.Type: GrantFiled: December 24, 2013Date of Patent: October 25, 2016Assignee: CHI MEI CORPORATIONInventors: Kuei-Lun Cheng, Kuan-Lin Hsieh, Chih-Cheng Lee
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Patent number: 9475918Abstract: Suitable stabilizers for organic material are a mixture comprising A. at least one oligomeric compound, comprising repeat units of the formula (I), in which the meanings of the symbols are as follows: R1 is hydrogen, C1-C6-alkyl, formyl, C2-C6-alkanoyl, C1-C12-alkoxy, C5-C6-cycloalkoxy, cyanomethyl, 2-hydroxyethyl, benzyl or a radical of the formula —CR??CH—CO—OR?, where R? is hydrogen, C1-C6-alkyl or a radical of the formula —CO—OR?, and R? is C1-C18-alkyl, C5-C8-cycloalkyl, C7-C18-aralkyl, phenyl, or tolyl; R2 is a mixture composed of C14-C28-alkyl groups, where two of these alkyl groups whose number of carbon atoms is not permitted to differ by more than two respectively make up at least 30% of this mixture; R3 and R4, independently of one another, are C1-C6-alkyl; and B.Type: GrantFiled: May 1, 2013Date of Patent: October 25, 2016Assignee: BASF SEInventors: Simon Schambony, Alban Glaser, Hubert Trauth, Manfred Appel, Sylke Haremza
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Patent number: 9475919Abstract: In accordance with some embodiments of the present invention, a composite material is prepared by blending a bio-derived filler into a polymer, wherein the filler includes a diene-modified cellulosic nanomaterial (e.g., cellulose nanocrystals (CNCs) and/or cellulose nanofibrils (CNFs) functionalized to contain a diene) and a dienophile-modified cellulosic nanomaterial (e.g., CNCs and/or CNFs functionalized to contain a dienophile). The modulus of the composite material is reversibly controllable by adjusting a degree of crosslinking between the diene-modified cellulosic nanomaterial and the dienophile-modified cellulosic nanomaterial. This degree of crosslinking is thermally reversible. On one hand, the degree of crosslinking may be increased via a Diels-Alder (DA) cycloaddition reaction at a first temperature, thereby increasing the modulus of the composite material.Type: GrantFiled: March 31, 2015Date of Patent: October 25, 2016Assignee: International Business Machines CorporationInventors: Dylan J. Boday, Joseph Kuczynski, Robert E. Meyer, III
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Patent number: 9475920Abstract: The present invention relates to a carbon fiber-reinforced polypropylene sheet which comprises carbon fibers having a weight-average fiber length of 1.5 mm to 20 mm and a matrix resin composed of a polypropylene and an acid-modified polypropylene, wherein the carbon fibers are dispersed in the form of single fibers and the interfacial shear strength between the carbon fibers and said matrix resin is 5.50 to 10.5 MPa. Provided is a carbon fiber-reinforced polypropylene sheet for obtaining a molded article having excellent mechanical properties and impact resistance, which carbon fiber-reinforced polypropylene sheet comprises discontinuous carbon fibers and a polypropylene, can be molded into a complex shape and has isotropic mechanical properties.Type: GrantFiled: November 16, 2012Date of Patent: October 25, 2016Assignee: Toray Industries, Inc.Inventors: Hidetaka Muramatsu, Noriyuki Hirano
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Patent number: 9475921Abstract: Compositions and methods of producing discrete nanotubes and nanoplates and a method for their production. The discrete nanotube/nanoplate compositions are useful in fabricated articles to provide superior mechanical and electrical performance. They are also useful as catalysts and catalyst supports for chemical reactions.Type: GrantFiled: June 21, 2012Date of Patent: October 25, 2016Assignee: Molecular Rebar Design, LLCInventors: Clive P. Bosnyak, Kurt W. Swogger
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Patent number: 9475922Abstract: Methods of synthesizing a binary polymer functionalized nanoparticle are generally provided. In one embodiment, a first anchoring compound is attached to a nanoparticle, and a first plurality of first monomers are polymerized on the first anchoring compound to form a first polymeric chain covalently bonded to the nanoparticle via the first anchoring compound. In another embodiment, a first polymeric chain can be attached to the nanoparticle, where the first polymeric chain has been polymerized prior to attachment to the nanoparticle. Thereafter, a second anchoring compound is attached to the nanoparticle, and a second plurality of second monomers are polymerized on the second anchoring compound to form a second polymeric chain covalently bonded to the nanoparticle via the second anchoring compound. Nanoparticles are also generally provided having multiple polymeric assemblies.Type: GrantFiled: August 10, 2015Date of Patent: October 25, 2016Assignee: University of South CarolinaInventors: Brian C. Benicewicz, Atri Rungta, Anand Viswanath, Linda S. Schadler Feist, Douglas Dukes
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Patent number: 9475923Abstract: A rubber composition by which a rubber elastic body having both of excellent low rolling resistance and wet skid resistance and also having excellent mechanical strength and wear resistance can be obtained, a rubber elastic body, a tire, and a block copolymer are provided. The rubber composition of the present invention comprises a block copolymer (A) comprising a block (a-1) of a conjugate diene and an aromatic vinyl and a block (a-2) of a conjugate diene or the diene and an aromatic vinyl, a specific polymer (B) other than the copolymer, and a filler (C), wherein the block copolymer (A) has a specific functional group; the block copolymer (A) has two glass transition temperatures separated from each other by 5° C. or more within a range of ?100 to 20° C. in measurement in accordance with ASTM D3418; and the ratio of the block copolymer (A) is 10% by mass or more when the sum of the block copolymer (A) and the polymer (B) is taken as 100% by mass.Type: GrantFiled: November 29, 2012Date of Patent: October 25, 2016Assignee: JSR CORPORATIONInventors: Takaomi Matsumoto, Ryoji Tanaka
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Patent number: 9475924Abstract: A rubber composition for tire tread contains a diene-based rubber including 30 wt % or more of a terminal modifying group-containing conjugated diene-based copolymer, silica, carbon black, and at least one of silane coupling agents represented by specified formulae. The total amount of silica and carbon black in the composition is 35 to 140 parts by weight relative to 100 parts by weight of the diene-based rubber, while the silane coupling agent content is 4 to 18 wt % on the silica content. The copolymer is produced by a specified method such that the aromatic vinyl monomer content in the copolymer is 38 to 48 wt %, the vinyl unit content in all the conjugated diene-based monomers is 20 to 35 mol %, the weight average molecular weight of the copolymer is 600,000 to 1,000,000, and the terminal modifying group in the copolymer contains a functional group which interacts with the silica.Type: GrantFiled: September 26, 2012Date of Patent: October 25, 2016Assignee: The Yokohama Rubber Co., Ltd.Inventors: Yoshihiro Kameda, Makoto Ashiura
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Patent number: 9475925Abstract: Provided are a blended rubber and a blended rubber composition that give a vulcanizate superior in abrasion resistance and ozone resistance, and a vulcanizate prepared by vulcanizing the blended rubber composition. A blended rubber, comprising 30 to 93 mass % of a chloroprene rubber, 5 to 50 mass % of a soft polyvinyl chloride, and 2 to 20 mass % of an acrylonitrile-butadiene rubber. The polyvinyl chloride resin used preferably has a polymerization degree of 300 to 3000 and the acrylonitrile-butadiene rubber preferably has an acrylonitrile content of 18 to 50 mass %.Type: GrantFiled: March 28, 2014Date of Patent: October 25, 2016Assignee: DENKA COMPANY LIMITEDInventors: Uichiro Yamagishi, Hideki Toya, Satoru Ikari, Yasushi Abe