Abstract: A dilator configured for dilating tissue of a corpora cavernosum of a penis having a dilation body defined along a longitudinal axis of the dilator and an extendable wing connected to the dilation body. A knob is provided at a first proximal end portion of the dilation body and is configured to communicate with the extendable wing. Rotating the knob extends the extendable wing away from the dilation body and changes an effective diameter of the dilator. Also disclosed is a method of dilating the corpora cavernosum of a penis and a method of implanting a penile prosthetic in the corpora cavernosum of a penis.

Abstract: Medical devices and methods are disclosed in the present application. In one illustrative example a medical device may comprise a catheter shaft extending from a proximal end to a distal end and the catheter shaft may include a plurality of catheter shaft lumens extending through at least a portion of the catheter shaft. The device may further include a first balloon member defining a first lumen in fluid communication with a first one of the plurality of catheter shaft lumens and a second balloon member defining a second lumen in fluid communication with a second one of the plurality of catheter shaft lumens. In some embodiments, the second balloon member may be disposed around the first balloon member and comprise a plurality of ports and a first raised portion and a second raised portion.

Abstract: A sinus dilation instrument useful with a navigation system and including a handle, a rigid probe, a balloon, and an identifier device. The probe extends from the handle, forms a curved segment, and carries the balloon. The identifier device is programmed to generate a signal indicative of an instrument identification assigned to the instrument, and is a frontal, maxillary or sphenoid sinus instrument. The signal is formatted to be recognized by an IGS. Once connected, the IGS recognizes the instrument and can retrieve information indicative of a spatial location of the balloon, for example via an instrument tracking device. A surgeon can “plug and play” the sinus dilation instrument with the IGS to perform a procedure.

Abstract: The purpose of the present invention is to provide a micro-needle unit and an injection device capable of being readily connected to a liquid supply source and capable of performing an effective injection via a simple configuration. The micro-needle unit is provided with a plurality of micro-needles disposed on the puncturing side and provided with a flow channel, and drug solution supply needles disposed on the side opposite from the puncturing side in a number less than that of the micro-needles and provided with a flow channel in communication with the aforementioned flow channel, the micro-needle unit thereby being capable of being readily connected to a liquid supply source and capable of performing an effective injection via a simple configuration.

Abstract: A multi-site electrode array (100) can include a microneedle array and a set of electrically active sites (115). The microneedle array includes a plurality of microneedles (105) supported on a base substrate (110). The set of electrically active sites (115) can be arranged at and/or near the tip of each microneedle (105), and in many cases along a shaft of the microneedles. Further, at least a portion of the active sites (115) can be independently electrically addressable such that a remaining portion of the active sites (115) are optionally electrically shunted together.

Abstract: A tattooing apparatus including a needle having at least one tip. The needle is configured to move between a first position in which the tip is located above the surface of a skin, and a second position in which the tip is located at a penetration depth underneath the skin surface. The needle is further configured to deposit an ink between the skin surface and the penetration depth. The tattooing apparatus further includes a needle drive mechanism configured to move the needle between the first position and the second position. The tattooing apparatus includes a sensor configured to output a feedback signal corresponding to a skin thickness characteristic. The tattooing apparatus further includes a controller configured to receive the feedback signal, wherein the controller is configured to adjust the penetration depth based on the skin thickness characteristic.

Abstract: A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element.

Abstract: A medical connector can include a body having a fluid path with an inlet port, an outlet port, a luer portion, and a post extending through a fluid path. An arm having a latch member is coupled to the body to engage a ridge or thread on an exterior surface of a reciprocal connector. The arm may also include an extension. When the connector is in an open position, the latch member restricts retraction of the reciprocal connector from the outlet port. A seal is coupled to the body and includes a flap extending across the outlet port or a bellows to compress along an axis. In a closed position, the post restricts flow through the luer portion. In an open position, the post permits flow through the luer portion.

Abstract: The present disclosure is directed to an IV cap that has a large grasping area and defines opening to allow the cap to be hung on an IV pole or other mount. The IV cap, once opened from a sterile packaging will connect to a female threaded, luer lock IV component: most likely a form of IV tubing or syringe. The IV cap will plug the connected IV tubing or syringe, maintaining sterility within the tubing system. The feature of the perforated tab of the IV cap will allow the user to hang the cap loop on an IV pole wire or hook.

Abstract: An apparatus for sampling, preparing and collecting biomedical samples for a subsequent diagnostic, clinical and/or therapeutic use in a closed sterile environment is provided.

Abstract: A connector includes a housing including: an insertion section into which a male connector is insertable from an outside of the housing, and a flow path communicating with the insertion section; and an elastic valve body having a slit and configured to block the insertion section. An inner wall of the housing defining the flow path is integrally formed with a liquid barrier face. The housing is configured such that, when the male connector is inserted in the insertion section, the liquid barrier face faces a tip opening of the male connector in an insertion direction of the male connector such that liquid flowing out from the tip opening collides with the liquid barrier face.

Abstract: Transcutaneous electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including nasal or paranasal sinus symptoms that resemble an immune-mediated response (“sinus” headaches). The devices and methods may also be used to treat rhinitis, sinusitis, or rhinosinusitis, irrespective of whether those disorders are co-morbid with a headache. They may also be used to treat other disorders that may be co-morbid with migraine or cluster headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated.

Abstract: Systems and methods of providing life support are provided. A life support system includes a first life support device that has a control unit and is configured to apply a life support protocol to a subject. The first life support device also includes a memory unit that can store life support protocol information, and the control unit can provide the life support protocol information to a second life support device. The control unit can also receive operating instructions from the second life support device based on the life support protocol information, and can implement the operating instructions.

Abstract: An electrotherapy cable is installed with plural conductive patches and is constituted by a plug terminal, a cable line, an LED element and a conductive connector. Accordingly, the connection state of an electrotherapy machine can be known through the display state of the LED element, so as to facilitate identifying the usage state of the electrotherapy machine.

Abstract: A method is provided that includes disposing midplane treatment electrodes over a superior sagittal sinus, outside and in electrical contact with a skull of a head of a subject identified as at risk of or suffering from Alzheimer's disease. Lateral treatment electrodes are disposed between 1 and 12 cm of a sagittal midplane of the skull. The subject is treated by electroosmotically driving fluid from a subarachnoid space to the superior sagittal sinus, by activating control circuitry to apply one or more treatment currents between (a) one or more of the midplane treatment electrodes and (b) one or sore of the lateral treatment electrodes. Other embodiments are also described. Other embodiments are also described.

Abstract: An electrode array having a splayable bundle of fibers having heat-sharpened tips. A method of manufacturing an electrode array including heat-sharpening a tip of each of a plurality of fibers; and bundling the plurality of fibers. A method of implanting an electrode array into a subject, the electrode array having a bundle of fibers, the method including exposing a target in the subject for the electrode array; and inserting the bundle of fibers into the target, where forces holding the bundle of fibers together are released during the insertion thus resulting in splaying of the fibers. An electrical connection with the fibers can be formed by a conductive material, or in high-channel count designs formed by surface mounting two-dimensional amplifier arrays to a base of a fiber array.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

Abstract: A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.

Abstract: An electric stimulator for brain, heart, skin and internal organs in animals and plants where the electrodes are distributed on a supporting structure. The supporting structure may be adapted for brain, heart, skin or other internal organs, as for DBS, heart pacemaker, TENS, etc. The invention discloses a plurality of electrodes at the surface of the supporting structure, from which electrically stimulating currents can be injected into the organism. Turning off an electrode while turning on another electrode has the effect of moving the stimulation within the body of the organism from one point to another point, with the same effect but with less spent energy than physically moving the whole electrode support. We call this electrode shifting. Rotational and translational electrode shifting are possible. The invention also discloses random changes of the electrode shifting, and random changes of the stimulation time and of the stimulation duration.

Abstract: Apparatus comprising (1) a breathing sensor, configured to detect a breathing-related factor of a subject; (2) at least a first electrode configured to be placed in a vicinity of a respective first hypoglossal nerve, and to be driven, in response to the detected breathing-related factor, to apply a first electrical current to the first hypoglossal nerve; (3) at least a second electrode configured to be placed in a vicinity of a respective second hypoglossal nerve, and to be driven, in response to the detected breathing-related factor, to apply a second electrical current to the second hypoglossal nerve; and (4) circuitry configured to, in response to a detected symmetry-related factor indicative of a degree of symmetry of the subject, configure at least one current selected from the group consisting of: the first current and the second current. Other embodiments are also described.

Abstract: The present invention is constituted by a body, an electric accumulator, an electric connecting wire, an electric quantity display module and an electric current control module. The electric accumulator is connected with the connector, an end of the electric connecting wire is provided with a butting connector which is connected electrically with the connector, and the other end of the electric connecting wire is provided with an electric current transmission element which is installed with a conductive patch. The electric quantity display module is connected electrically with the electric accumulator and the electric current control module is connected with the electric accumulator, so as to control the magnitude and intensity of electric current output in the electric accumulator, and update the electrotherapy mode wirelessly.

Abstract: This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.

Abstract: An implantable system, and methodology, for improving a heart's hemodynamic performance featuring (a) bimodal electrodes placeable on the diaphragm, out of contact with the heart, possessing one mode for sensing cardiac electrical activity, and another for applying cardiac-cycle-synchronized, asymptomatic electrical stimulation to the diaphragm to trigger biphasic, diaphragmatic motion, (b) an accelerometer adjacent the electrodes for sensing both heart sounds, and stimulation-induced diaphragmatic motion, and (c) circuit structure, connected both to the electrodes and the accelerometer, operable, in predetermined timed relationships to the presences of valid V-events noted in one of sensed electrical and sensed mechanical, cardiac activity, to deliver diaphragmatic stimulation.

Abstract: A method of generating frequency-modulated pulse trains in a CI includes dividing data representing audio spanning frequency bands into a plurality of bins associated with each frequency band, each bin representing an energy level of the data within the frequency band within a period of time; associating each frequency band with a phase probability that starts at an initial phase probability value (PPV), resets to a minimum PPV after generating a pulse, and increases from the minimum PPV to a maximum PPV over a period of time; for each bin, assigning a power probability as a normalized intensity being a number between a minimum power probability and a maximum power probability representing the energy level of the bin, and generating a pulse in an electrode associated with the frequency band associated with the bin when a random number generated is less than the power probability divided by the phase probability.

Abstract: An arrangement for reducing intraocular pressure includes a pulse signal source, a probe coupling, and at least one electrode. The probe coupling is configured to be supported on a portion of a living eye. The electrodes are supported on the probe coupling. The electrodes are operably coupled to receive a pulse signal from the pulse signal source.

Abstract: An artificial retinal prosthesis system comprises an extraocular optical device and an intraocular retina chip. The extraocular optical device receives an external image, converts it into an optical pulse signal, and generates light energy. The intraocular retina chip receives the optical pulse signal from the extraocular optical device and produces an electric simulation signal. The intraocular retina chip includes a solar cell module receiving and converting the light energy into electric energy as a power source of the intraocular retina chip. The artificial retinal prosthesis system uses an optical modulation method to convert an image signal into an optical pulse signal, transmits the optical pulse signal into the eyeball, and decodes the optical pulse signal intraocularly. Thereby, the signal light intensity is improved without affect the contrast ratio.

Abstract: An implantable pulse generator that includes a current source/sink generator is disclosed herein. The current source/sink generator includes a current drive differential amplifier. The current driver differential amplifier is configured to selectively source current to, or sink current from a target tissue. The current drive differential amplifier includes an inverting input and a non-inverting input. One of the inputs of the current drive differential amplifier is connected to a virtual ground, and the other is connected to a current command. A stimulation controller can supply a voltage to the other of the inputs of the current drive differential amplifier to select either current sourcing or current sinking.

Abstract: Disclosed herein is an implantable pulse generator for administering electrotherapy via an implantable lead. The pulse generator includes a housing and a header connector assembly. The housing includes a first portion of a cam lock arrangement. The header connector assembly includes a connector assembly, a header enclosing the connector assembly, and a second portion of the cam lock system cam locked with the first portion in anchoring the header connector assembly to the housing.

Abstract: An apparatus comprises a communication channel comprising a plurality of disparate sequential communication links configured to facilitate bi-direction communication between an implantable medical device (IMD) and a programmer. A transceiver is configured to communicate with the programmer via a first communication link of the plurality of disparate communication links. A telemetry device is configured to communicate with the IMD via a second communication link of the plurality of disparate communication links. A third communication link communicatively couples the transceiver and the telemetry device. A power source is coupled to the transceiver and to the telemetry apparatus. An operational status of at least the first and second communication links can be individually determined in real-time.

Abstract: A patient programmer has a housing having a key-fob-sized form factor. The patient programmer has electrical circuitry implemented inside the housing. The electrical circuitry includes a communication module configured to conduct wireless communications with an implantable pulse generator. The patient programmer has a user display implemented on the housing. The user display is configured to display one or more statuses of the implantable pulse generator. The implantable pulse generator is configured to generate an electrical stimulation therapy. The patient programmer has one or more buttons implemented on the housing. The one or more buttons are configured to send instructions, via the communication module, to the implantable pulse generator to adjust a stimulation parameter of the electrical stimulation therapy.

Abstract: In one embodiment, a method, of operating an implantable medical device, comprises: (i) operating reset logic within the implantable medical device that is independently operable from a processor of the implantable medical device after the implantable medical device is implanted within a patient, wherein the processor is adapted for central control of the implantable medical device; (ii) operating a magnetic field sensor in the implantable medical device; (iii) generating digital data using, at least, the magnetic field sensor; (iv) detecting, by the reset logic, a digital key in the digital data; (v) in response to (iv), asserting a reset signal on a pin of the processor by the reset logic; and (vi) conducting reset operations in the processor in response to the reset signal.

Abstract: A method and system for use with an implantable medical device for subcutaneous implant within a patient to determine a likelihood of the patient experiencing a cardiac event that includes sensing a cardiac signal along a plurality of different sensing vectors, determining state information of each vector of the plurality of sensing vectors, determining a cross correlation of the determined state information of each vector of the plurality of sensing vectors, comparing the cross correlation of the determined state information of each vector of the plurality of sensing vectors to a threshold, and detecting the cardiac event in response to the comparing.

Abstract: A system includes a first computing device comprising a processor coupled to a memory. The processor and the memory are configured to receive at least one of (i) information indicative of treatment of a victim by a first caregiver using the first computing device and (ii) information indicative of a health status of the victim; determine that treatment of the victim by the first caregiver using the first computing device is completed; and transmit the received information to a second computing device.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: There is provided a body illumination device (100) adapted to surround at least a part of a user (102) comprising at least one inflatable structural element and a light emitter (120). The at least one inflatable structural element includes a first inflatable structural element (110). The first inflatable structural element (110) comprises a first inflatable chamber (112) comprising a first wall (114). The light emitter (120) is on or integrally formed with said first wall (114) and is for providing light to the user (102). The body illumination device (100) may be stored easily in a deflated state. Further, the body illumination device (100) does not require relatively expensive structural components, such that it may be provided in a cost-effective manner. Additionally, the device (100) may be easy to use. The device (100) may be used in a method of treatment comprising providing treatment light to the user (102). The treatment may be of psoriasis, eczema or skin cancer, in particular.

Abstract: Methods and apparatus are described that use an array of light sources that project converging light beams to control treatment distance. This approach controls treatment distance without contacting the patient or increasing the risk of pathogenic contamination. The approach can be used to control an optimal distance, and is compatible with various medical treatment devices including cold plasma treatment devices.

Abstract: A treatment device configured to illuminate a surface of a 3D skin surface when positioned adjacent the illuminated surface of the 3D skin surface. The treatment device includes a number of linear light source strips to conformally illuminate the 3D skin surface.

Abstract: A phototherapy or BRT process and apparatus is provided, which, using a pre-recorded bioresonance frequency or compilation of frequencies, causes an EMR emitter to emit within a biological window of a target organism to positively or negatively affect the organism. The EMR may be generated in one or more LEDs by a device connected to a controller of the EMR emitter which device provides the pre-recorded bioresonance frequency or compilation of frequencies to control the LEDs' emitted light in terms of its intensity and/or a frequency or flicker-rate.

Abstract: A particle beam treatment system having a beam generation unit for generating a beam of charged particles, in particular ions, preferably protons, and having a beam guidance system. The generic beam guidance system takes up less space but can provide comparable or even improved beam properties because, in part, the beam guidance system seen in the direction of the beam of charged particles and behind the beam generation unit has at least one solenoid magnet as a beam shaping unit, and the at least one solenoid magnet of the beam guidance system is a superconducting solenoid magnet.

Abstract: An applicator device (100, 200, 300) for use in interventional brachytherapy, wherein the applicator device (100, 200, 300) is configured to be inserted in, or near a region of interest within a living body, and the applicator device is defining a lumen (101, 201, 301) for receiving a radiation source (103, 203, 303), characterized in that the applicator device (100, 200, 300) comprises one or more sensor elements (102, 202, 302) each configured to generate an output signal indicative of whether or not the radiation source (103, 203, 303) is at a predetermined position in the lumen (101, 201, 301).

Abstract: A radiotherapy apparatus comprises a rotatable gantry, supporting a source of therapeutic radiation and a source of diagnostic radiation, the two sources being rotationally (or angularly) spaced apart around a rotation axis of the gantry, with at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a control means arranged to conduct a treatment fraction using the apparatus by causing the apparatus to i. acquire images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. subsequently, after further rotation of the gantry, select a retained image acquired when the source of diagnostic radiation was at a rotational position corresponding to the instantaneous rotational position of the source of therapeutic radiation, and iv. control the beam relative to the patient using information derived from the selected image.

Abstract: An ultrasound device for therapeutic and aesthetic treatment is disclosed. Different types of hand probes used with the device produce different effects within biological tissues. The device can operate at low frequencies of around 20 KHz to 100 KHz. The device can be operated in continuous mode or pulsed mode with different duty cycles. Software and hardware is used to control power output of the hand probes; treatment time; to perform diagnostics of the hand probes; and to shut off ultrasound emissions in the case of abnormal or incorrect functioning of the hand probes.

Abstract: An ultrasonic medical probe has a horn or shaft, a shank at a proximal end of the shaft, a probe head at a distal end of the horn or shaft, opposite the shank, and at least one polymeric component fixed to at least one of the horn or shaft, the shank, and the probe head. The shank is provided at a proximal end opposite the horn or shaft with an externally threaded connector for attaching the probe to a source of ultrasonic vibratory energy. The polymeric component is of a composition that transmits and is essentially impervious to ultrasonic vibratory energy but that degrades or decomposes upon exposure to a source of extreme energy (other than ultrasonic vibratory energy), rendering the probe inoperative for use.

Abstract: In some examples, a system includes a flexible ultrasound device configured to be attached to an external surface of a patient proximate to an organ of the patient to deliver ultrasound configured to modulate nerve tissue of the patient at the organ. The system further comprises one or more sensors configured to sense one or more physiological parameters indicative of at least one of a symptom treatable by, or a side effect of, the neuromodulation, and processing circuitry configured to control the delivery of ultrasound during an ambulatory period of the patient, and monitor the least one of the symptom or the side effect during the ambulatory period, based on the one or more physiological parameters. The organ may be the spleen and the ultrasound may at least one of regulate the autoimmune system of the patient, or reduce an inflammation response of the patient.

Abstract: An ultrasonic treatment device includes a first vibration transmitting member and a second vibration transmitting member and being configured to treat a biological tissue by means of vibration transmitted by the first vibration transmitting member and the second vibration transmitting member. At a boundary position between the first vibration transmitting member and the second vibration transmitting member, the first vibration transmitting member has a boundary face including a contacting area that is in contact with the second vibration transmitting member at the face, and a non-contacting area that is not in contact with the second vibration transmitting member.

Abstract: A therapeutic ultrasonic transducer including: a transducer body that has, in the stated order along the longitudinal axis, a first metal body, a laminated body in which a plurality of piezoelectric elements are laminated in the longitudinal-axis direction such that their directions of polarization are set in opposite directions in an alternating manner, and a second metal body, and that is formed by integrally fastening the metal bodies and the laminated body with a bolt; and a heat-radiation means that is connected at a position, on the transducer body, serving as a node of an ultrasonic vibration, or in the vicinity of that position.

Abstract: The present invention relates to a process for treating keratin fibers such as the hair using a packaging article comprising i) an envelope defining at least one cavity, the envelope comprising water-soluble and/or liposoluble fibres, preferably water-soluble fibres; ii) at least one anhydrous oxidizing composition, preferably in paste or powder form, comprising at least one anhydrous chemical oxidizing agent, preferably in paste or powder form; it being understood that the oxidizing composition is in one of the cavities defined by the envelope i).

Abstract: The brake system composes a circular wheel, brake shoes, brake disc and cable reel rotation. The rubbing action between brake shoes and brake disc generating from the rotation of Axle rotating with the planetary gear, which is driven by the cable reel, reduces the falling speed. (Falling speed about 1.7 meters per second) The inner cable is designed with a length of 82 meters and max load of 177 kg. The decelerator of this device could stop the falling immediately by using hand brake, in order to achieve rescue and avoid probable injure.

Abstract: A system for rendering safe a site above which an individual is operative at height which comprises at least one self-inflating fall arrest unit in a fully inflated state is arranged at a ground location on the site. At least one of the self-inflating fall arrest units in a fully inflated state is linked to at least one other fully inflated self-inflating fall arrest unit. Each of the self-inflating fall arrest units comprise at least one battery-powered fan. A method of rendering safe a site above which an individual is operative at height is also described.