Abstract: A noninvasive remote parameter sensor and sensing method is provided that is particularly suited for the remote monitoring of skin temperature. The sensor and sensing method utilize luminescence-based sensors that are non-toxic and non-irritating to the skin. The sensor preferably utilizes one or more types of fluorophores that are embedded in a soft hydrogel. The sensor is illuminated with excitation light, and temperature is monitored by detecting and analyzing the emission light from the fluorophores. Because a soft hydrogel is used, the sensor can be gently wiped off the skin at the conclusion of temperature measurements.

Abstract: A three-dimensional electronic patch includes a flat flexible circuit substrate that includes an elastic layer including a first portion and a second portion. The second portion includes at least side connected to the elastic layer and one or more sides defined by one or more cuts in the elastic layer. The three-dimensional electronic patch further includes a first sensor on the first portion of the elastic layer, a first conductive sensing pad under the first portion of the elastic layer and in electrical connection with the first sensor, and a conductive layer under the second portion of the elastic layer and in electrical connection with the first sensor. The second portion is folded to position the conductive layer away from the first portion.

Abstract: A medical instrument includes a remaining visits indicator. The remaining visits indicator visually identifies a number of patient visits that can be completed before recharging the medical instrument.

Abstract: The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and beat-to-beat basis. Cardiovascular indices which can be estimated include: stroke volume (SV), which being limited to, cardiac output (CO) and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods describe herein can provide a more accurate and reliable estimate of hemodynamic parameters than existing techniques.

Abstract: A patient monitoring system may receive a physiological signal such as a photoplethysmograph (PPG) signal. The PPG signal may include a pulsatile component that functions as a carrier signal and an amplitude modulation component that represents respiration information. The patient monitoring system may move the amplitude modulation component to a baseline component of the PPG signal. Respiration information may be calculated based on the amplitude modulation component.

Abstract: A sensing/pacing lead including a microcable having a diameter of at most 2 French (0.66 mm). The microcable includes an electrically conductive core cable including a plurality of strands and a composite structure formed from at least a structuring material and a radiopaque material, the radiopaque material constituting at least about 0.008 mm2 of the core cable cross section. The plurality of strands of the core cable comprises a first set of individual strands formed from the structuring material and a second set of individual strands formed from the radiopaque material, or a plurality of strands each comprising a first and second layer, one of which is the structuring material and the other the radiopaque material. The microcable further includes a polymer insulation layer at least partially surrounding the core cable and at least one electrode.

Abstract: An implantable medical device (IMD) is implanted in a patient. The IMD uses a plurality of electrode vectors to generate intrathoracic impedance measurements. The intrathoracic impedance measurements can be indicative of amounts of intrathoracic fluid in the patient. An accumulation of intrathoracic fluid may indicate that the patient is at an increased risk of experiencing a heart failure event in the near future. The IMD performs a vector selection operation on a recurring basis. When the IMD performs the vector selection operation, the IMD uses impedance measurements to select one of the electrode vectors. The IMD can perform a risk assessment operation on another recurring basis. During performance of the risk assessment operation, the IMD uses impedance measurements of the selected electrode vector and/or other patient characteristics stored within the IMD to determine whether the patient is at an increased risk of experiencing a heart failure event.

Abstract: The current subject matter relates to indicating extent and location of myocardial ischemia in a patient. Electrodes can be placed on a body of the patient. Signal amplifiers can receive orthogonal electrical signals from the electrodes via three bipolar leads. The signal amplifiers can amplify the signals and send the amplified signals to analog to digital converters. The analog to digital converters can convert the amplified signals to digital signals. A computing device can execute a data analysis application that can receive these digital signals, generate QRS complexes associated with these signals, generate depolarization vectors associated with these QRS complexes, and then determine changes in magnitudes and directions of these vectors. Based on the changes in magnitudes and directions, the data analysis application can determine and display extent and location of myocardial ischemia in the patient. Related apparatus, systems, methods, techniques and articles are also described.

Abstract: A method for sensing multiple local electric voltages from endocardial surface of a heart, includes: providing a system for sensing multiple local electric voltages from endocardial surface of a heart, including: a first elongate tubular member having a lumen, a proximal end and a distal end; a basket assembly including: a plurality of flexible splines for guiding a plurality of exposed electrodes, the splines having proximal portions, distal portions and medial portions therein between, wherein the electrodes are substantially flat electrodes and are substantially unidirectionally oriented towards a direction outside of the basket.

Abstract: The present invention provides a method for creating and pathophysiologically analyzing graphs of cardiac function in atrial fibrillation and sinus arrhythmia by using thoracic impedance measurements. A two-dimensional scatter plot is created by applying (dZ/dt)min values corresponding to preceding RR interval (RR1) values and an approximate curve (i.e., cardiac function curve) is fitted to dots on the plot. The distribution pattern of the dots and the slope of the approximate curve allow for readily and visually evaluating cardiac function. Furthermore, a graph of the relationship between (dZ/dt)min values and RR1/pre-preceding RR interval (RR2) ratio values makes it possible to analyze pathophysiological mechanisms of cardiac function in more detail. This novel method of the present invention can be easily and repeatedly performed in atrial fibrillation and sinus arrhythmia with less of a physical burden on the patient, thereby being able to provide a very useful information for diagnosis and treatment.

Abstract: A system analyzes neuro-response measurements including regional electroencephalography (EEG) measurements from subjects exposed to stimulus materials to determine locations in stimulus materials eliciting controlled attention and automatic attention. Additional stimulus materials are inserted into locations having salient attention attributes. In some examples, a challenging task is used to direct controlled attention onto a location and additional stimulus material is subtly presented in the location to benefit from automatic attention and salient attention measurements.

Abstract: A medical magnetometer 10 comprising one or more induction coils 2 for detecting a time varying magnetic field of a region of a subject's body, such as the heart. Each coil has a maximum outer diameter of 4 to 7 cm, and a configuration such that the ratio of the coil's length to its outer diameter is at least 0.5, and the ratio of the coil's inner diameter to its outer diameter is 0.5 or less. Each induction coil 2 is coupled to a respective detection circuit comprising a low impedance pre-amplifier 3, a low pass filter 5, a notch filter 6 to remove line noise, and an averaging element 7. Each detection circuit produces an output signal 9 for use to analyze the time varying magnetic field of the region of the subject's body.

Abstract: Spatial light response around a fingertip or toe of a subject in response to electrical stimulation can be associated to a specified remote particular body anatomy, location, component, or system such as for providing a particularized physiological status indicator or other particularized response indication that is particular to the specified particular body anatomy, location, component, or system.

Abstract: A system for visually rendering an elongate medical device in a body is provided. The system includes an electronic control unit configured to find a measured physical location for each of a plurality of position sensors on the elongate medical device. The electronic control unit is further configured to apply a spline function to each of the measured physical locations to determine a display location for each position sensor. The electronic control unit is further configured to interpolate between display locations of adjacent position sensors to identify display locations for portions of the elongate medical device between adjacent position sensors. The electronic control unit is further configured to generate image data for display of an image of the elongate medical device including the display locations of the position sensors and the display locations of the portions of the elongate medical device between adjacent position sensors.

Abstract: A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.

Abstract: The disclosure relates to a method and system for obtaining baseline patient information. In some examples, a method may include acquiring first patient data, wherein the first patient data comprises at least one of first posture state data indicative of a plurality of posture states of a patient during a first time period or first therapy adjustment data indicative of a plurality of patient therapy adjustments made during the first time period; generating baseline patient information based at least in part on the first patient data; and comparing the baseline patient information to patient information generated based on second patient data. Therapy is not delivered to the patient according to a detected posture state of the patient during the first time period, and therapy is delivered to the patient according to the detected posture state of the patient during the second time period.

Abstract: A system for establishing a hearing ability model of a hearing ability of a person, includes a data storage configured to store a representation of a distribution of a hearing ability of a population of individuals, and a processor configured to establish a hearing ability model representing a hearing ability of the person based at least in part on (i) information regarding a person's response to a stimulus of a hearing evaluation event, and (ii) the representation of the distribution of the hearing ability of the population.

Abstract: Methods and systems for endoscopic observation of tympanic function.

Abstract: A blood testing apparatus includes a laser source configured to produce a wound from which blood flows and at least one test member. A humidity cover is positioned at the at least one test member. The humidity cover is at least partially removable. Electronics are provided for analysis. The electronics includes an evaluation device for comparisons with previously stored measurements or evaluation data with the evaluation device storing a current test measurement.

Abstract: Embodiments disclosed herein may include systems and methods for reducing power consumption of a pulse oximeter. The disclosure describes method for measuring oxygen saturation of a patient's blood with a pulse oximeter that switches between a high power mode of operation and one or more low power modes of operation based at least in part upon the data obtained from the patient or otherwise generated by the pulse oximeter. In one embodiment, the disclosure describes a operating a pulse oximeter in a high power mode, the pulse oximeter using a sensor to generate data indicative of the oxygen saturation of the patient's blood at a first resolution and switching the pulse oximeter to a low power mode upon detection of data indicative of a non-critical situation. The low power mode may be selected from a set of available low power modes based at least in part upon the data generated by the pulse oximeter.

Abstract: A physiological monitoring system may determine a probe-off condition. A physiological sensor may receive a light signal including one or more wavelengths of light. The received light signal may be processed to obtain a light signal corresponding to an ambient light signal and a light signal corresponding to an emitted light signal and the ambient light signal. The signals may be analyzed to identify an inverse effect. The system may determine whether the physiological sensor is properly positioned based on the identification of an inverse effect.

Abstract: A system for operating third party proprietary software on a medical monitoring device operating native proprietary software and a system for obtaining compatible third party proprietary software for operation on the monitoring device.

Abstract: A biological signal measuring system includes: a light emitter emitting light beams having different N kinds of wavelengths, where N is an integer of four or more; a light receiver outputting N kinds of signals respectively in accordance with received light intensities of the N kinds of light beams that have been passed through or reflected from a living tissue; a first calculating section acquiring N kinds of light attenuations based on the N kinds of signals; a second calculating section acquiring (N?1) kinds of blood-derived light attenuations based on two light attenuations related to (N?1) kinds of combinations selected from the N kinds of light attenuations; a third calculating section identifying concentrations of (N?1) kinds of in-blood substances based on the (N?1) kinds of blood-derived light attenuations; and an outputting section outputting the identified concentrations.

Abstract: Aspects of the present disclosure include a sensor configured to store in memory indications of sensor use information and formulas or indications of formulas for determining the useful life of a sensor from the indications of sensor use information. A monitor connected to the sensor monitors sensor use and stores indications of the use on sensor memory. The monitor and/or sensor compute the useful life of the sensor from the indications of use and the formulas. When the useful life of the sensor is reached, an indication is given to replace the sensor.

Abstract: A glucose tolerance analyzer comprising: an accepting section configured to accept inputs of information regarding a type of food or drink ingested by a subject, information regarding an intake amount of the food or drink, and information regarding an amount of glucose in the subject after the ingestion of the food or drink; an output section configured to output an analysis result of glucose tolerance; and a controller configured to: calculate a reference value for analyzing glucose tolerance of the subject based on the accepted information regarding the type of the food or drink ingested by the subject and the information regarding the intake amount of the food or drink, and based on a predetermined index regarding blood glucose increase due to food or drink; analyze the glucose tolerance of the subject based on the accepted information regarding the amount of glucose and based on the calculated reference value; and control the output section to output an obtained analysis result as an analysis result of gl

Abstract: A body fluid sampling device for use on a patient includes at least one penetrating member positioned in the cartridge and a sample port for receiving a body fluid. A channel is coupled to the sample port and the sample chamber. At least a portion of the channel is a capillary channel positioned adjacent to the sample chamber. A mesh membrane is and provides that the body fluid contacts the channel regardless of an orientation of body fluid sampling device.

Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: The present invention relates to a system device and method for monitoring infant oral motor kinetics (OMK), which can be used to assess the functional significance of the different sucking components, i.e., the plasticity of infant sucking skills in relation to their oral feeding performance, at a particular time, during the developmental period and/or during preventive or therapeutic intervention programs. It is a unique system and apparatus that provides a means to study the nonnutritive and/or nutritive sucking skills, i.e., the Suction and/or Expression components of sucking, of infants in the natural setting, i.e., during a normal feeding session.

Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.

Abstract: Systems, methods, computer programs, and circuits can perform automated spinal assessments using a 3-D model and a 3-D patient image data set of the spine which do not rely on vertebral symmetry.

Abstract: Techniques are described for generating beat templates and utilizing those beat templates to detect a cardiac event, e.g., a tachyarrhythmia. In particular, example methods and devices for acquiring qualified beats for template generation are described. Additionally, techniques are described for selecting subsets of the qualified beats to actually use in generating a beat template.

Abstract: An embodiment of the invention provides a method for determining a patient-specific probability of renal transplant survival. The method collects clinical parameters from a plurality of renal transplant donor and patient to create a training database. A fully unsupervised Bayesian Belief Network model is created using data from the training database; and, the fully unsupervised Bayesian Belief Network is validated. Clinical parameters are collected from an individual patient/donor; and, such clinical parameters are input into the fully unsupervised Bayesian Belief Network model via a graphical user interface. The patient-specific probability of disease is output from the fully unsupervised Bayesian Belief Network model and sent to the graphical user interface for use by a clinician in pre-operative organ matching. The fully unsupervised Bayesian Belief Network model is updated using the clinical parameters from the individual patient and the patient-specific probability of transplant survival.

Abstract: To provide an X-ray diagnostic apparatus capable of providing a stereoscopic perspective image in the form of a video image while reducing exposure dose. An X-ray diagnosis apparatus according to an embodiment includes: a main row X-ray source group including a plurality of X-ray sources; an X-ray detection section disposed opposite to the X-ray sources; a timing controller that controls a switching timing of the X-ray sources and an X-ray generation position; an image acquisition section that acquires output image data from the X-ray detection section in synchronization with the switching timing; and a stereoscopic image display section that displays the output image data as a plurality of images having different disparities.

Abstract: In one embodiment, a method of displaying image in an imaging system is provided. The method comprises steps obtaining an image from an radiation detector, receiving a selection for orientation from a user, mechanically rotating the radiation detector based on the selection for orientation and performing a digital image rotation on the image complementing the mechanical rotation of the radiation detector such that the image is rotated to the orientation selected by the user and displaying the image.

Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The arm may be articuable. The X-ray tube may include a target element configured to generate an X-ray beam and a collimator configured to shape the X-ray beam. The target element may be disposed at a set distance from the collimator.

Abstract: An imaging system including a scanner for scanning an object and creating an image of the same; and a transport mechanism mounted to the scanner for moving the scanner, wherein the transport mechanism includes a gross movement mechanism for transporting the scanner between scanning locations; and a fine movement mechanism for moving the scanner precisely, relative to the object being scanned, during scanning of the object; wherein the gross movement mechanism comprises at least one motorized wheel.

Abstract: An X-ray CT apparatus includes a perfusion data acquisition unit, a perfusion parameter calculating unit and a perfusion parameter display unit. The perfusion data acquisition unit generate perfusion data by exposing an X-ray to the object with injecting contrast medium. The perfusion parameter calculating unit calculates perfusion parameters corresponding to ROIs based on time variations in density of the contrast medium for the ROIs. The perfusion parameter display unit divides a period to be a calculation target of the time variations into plural time ranges and sequentially displays images each including the ROIs. The images correspond to the time ranges and mutually different time phases respectively and are masked so as to make only ROIs at which the perfusion parameters show values displayed.

Abstract: Provided are a method of deciding the risk of obstructive sleep apnea syndrome capable of deciding the risk of a subject to become obstructive sleep apnea syndrome objectively and easily in a short time, its program and an X-ray diagnostic system having the program. The method includes detecting at least the hyoid bone, sella S, gonion Go and menton Me by lateral head and neck radiography of the subject; and deciding whether the center of the body or the whole of the body of the detected hyoid bone is included in an area above a perpendicular drawn toward the extended line of the segment S-Go from Me or not.

Abstract: A movable radiographing apparatus has a wireless communication function and includes a radiation generating unit including a radiation source, an arm portion configured to support the radiation generating unit, a support pillar configured to support the arm portion, and a moving unit configured to support the support pillar and including a GUI to be operated by the user. The movable radiographing apparatus further includes a connector unit to and from which an external antenna for wireless communication is attachable and detachable, wherein the connector unit is provided on at least one of the radiation generating unit, the arm portion, the support pillar, and the moving unit.

Abstract: An X-ray imaging apparatus includes: an X-ray sensor configured to convert an X-ray to an image signal; a battery configured to supply electric power for driving the X-ray sensor; a battery holder configured to detachably hold the battery; a lock mechanism configured to lock the battery in a state in which it is attached to the battery holder; and a lock releasing mechanism configured to release the lock effected by the lock mechanism, wherein the lock releasing mechanism is configured to release the lock by the lock mechanism through at least two operations performed by the operator.

Abstract: An ultrasound system comprises a probe for acquiring ultrasound data associated with a patient and a microphone detecting audio. The system further comprises a processor module and a memory. The processor module is configured to receive the ultrasound data from the probe and processes the ultrasound data to form an image file. The processor module is further configured to receive the audio from the microphone and forms a voice recording file based on the received audio. The memory stores the image file and the voice recording file, and the processor module automatically associates the image file and the voice recording file with each other.

Abstract: Systems and methods which operate to identify interventional instruments and/or other objects in images are shown. Embodiments operate to extract relevant information regarding interventional instruments from a multi-dimensional volume for presenting the information to a user in near real-time with little or no user interaction. Objects may be identified by segmenting a multi-dimensional volume, identifying a putative object of interest in multiple multi-dimensional volume segments, and determining a position of the object of interest within the multi-dimensional volume using the putative object of interest segment identifications. Identification of objects of interest according to embodiments may be utilized to determine an image plane for use in displaying the objects within a generated image, to track the objects within the multi-dimensional volume, etc., such as for medical examination, interventional procedures, diagnosis, treatment, and/or the like.

Abstract: The present disclosure provides for a system that is adapted to simultaneously display photoacoustic and ultrasound images of the same object. An image combiner can perform spatial and temporal interpolation of the two images before generating a combined image. The combined image is then displayed on a display such as an LCD or CRT. The system is able to use motion estimates obtained from the ultrasound data to enhance the photoacoustic image thereby increasing its apparent frame rate, registering consecutive frames in order to reduce artifacts. The system is capable of generating combined ultrasound and photoacoustic images which are registered spatially and temporally.

Abstract: A diagnosis image generating apparatus including a plurality of probes, the diagnosis image generating apparatus including at least one element included in each of the plurality of probes; a selecting unit which selects a probe from among the plurality of probes; and a diagnosis image generating unit which generates a diagnosis image of the object by using the selected probe.

Abstract: A shared-housing ultrasound transducer and machine-vision camera system is disclosed for registering the transducer's x, y, z position in space and pitch, yaw, and roll orientation with respect to an object, such as a patient's body. The position and orientation are correlated with transducer scan data, and scans of the same region of the object are compared in order to reduce ultrasound artifacts and speckles. The system can be extended to interoperative gamma probes or other non-contact sensor probes and medical instruments. Methods are disclosed for computer or remote guiding of a sensor probe or instrument with respect to saved positions and orientations of the sensor probe.

Abstract: A biopsy system includes a biopsy targeting assembly, a needle, and a biopsy device. The biopsy targeting assembly includes a cradle. The needle is releasably supported by the targeting assembly. The biopsy device includes a body having a tissue collection assembly and a cutter. The cutter is translatable relative to the body and extends distally from the body. The cradle of the targeting assembly releasably supports the body of the biopsy device distally of the tissue collection assembly. The biopsy device translates a distal portion of the cutter within the needle with the needle supported by the targeting assembly.

Abstract: Embodiments include a method of performing a medical procedure in a patient. The method includes inserting a first working instrument and a second working instrument through an opening in the patient, creating an incision in body tissue inside the patient using at least one of the first and second working instruments, and advancing the second working instrument through the incision to position the second working instrument at a work site inside the patient. The method also includes positioning the first working instrument at the work site without advancing the first working instrument through the incision and performing a procedure at the work site inside the patient using the first and second working instruments.

Abstract: An optical metrology and image correction device includes a point size light source adapted to emit a beam of light and a translucent mask that receive the beam of light. The translucent mask rotates from a first position wherein the beam of light is received by the translucent mask in a direction substantially orthogonal to the translucent mask to a second position wherein the beam of light is received by the translucent mask at an angle offset with respect to the translucent mask. A corresponding method of measuring and correcting an image from an optical metrology and image correction device includes emitting a beam of light from a point size light source, causing the beam of light to be received by a translucent mask in a first position substantially orthogonal to the mask and in a second position in a direction offset with respect to the translucent mask.

Abstract: Methods and devices for providing improved ultrasound visibility of medical devices intended for intravascular use are described. The inclusion of gas/solid boundary regions within a medical devices improves the resolution of the device under ultrasound visualization. Gas/solid boundary regions may be provided through the use of embedded gas-filled microlumens, microwells, or enclosed pockets within the medical device.

Abstract: An incrementally adjustable wound retractor (500), having a first ring (504) with a diameter greater than the desired diameter of the wound incision, a flexible second ring (502), having a lumen and a diameter greater than the desired diameter of the wound incision, and a flexible sleeve (506), disposed in a generally cylindrical form between the first and second rings (502, 504), where the second ring may be rolled over itself to provide a sleeve with a radical retraction force sufficient to stretch the incision to the desired diameter.