Abstract: A combination physiologic status sensor system is described. It integrates a highly efficient reflectance oximeter, acquisition of a 2-lead electrocardiogram (“ECG”) heart rate signal, a photonic indicator of molecular products of anaerobic metabolism, and a skin temperature sensor. Placement of this motion tolerant sensor system may be on the adult or child subject's upper arm or infant chest, or chest and abdomen, for acquisition of high quality signals. Efficient use of battery power, combined optionally with wireless communications, enables continuous ambulatory use for extended periods of time. The comprehensive physiologic profile provided by this multi-factorial sensor and analysis system is anticipated to be of benefit in providing physiologically important, actionable information in a wide range of applications, including athletic training and performance, high risk occupational safety monitoring, and critical and convalescent medical care of patients of all ages and sizes.

Abstract: A method for monitoring blood pressure includes sensing and storing sympathetic nerve activity data of a patient via a recording lead of an implantable medical device. Changes in sympathetic nerve activity from the nerve activity data are determined. Corresponding changes in blood pressure are determined from the changes in sympathetic nerve activity. An alert signal and/or modification of therapy can be provided.

Abstract: A monitoring device wearable by a person to be monitored, comprising: one or more sensing means for sensing cardio, respiratory, physiological and/or other information from the person; processing means for analysing the sensed information; memory means for storing the sensed and/or analysed information; and communication means for transmitting at least the analysed information. At least one waveform acquired from the sensed cardio, respiratory, physiological and/or other information is digitised in real time; analysis of the sensed and/or digitised information is performed in real-time and a welfare indication of the person computed in real-time; and the computed welfare indication of the person is transmitted by the communication means and/or stored in the memory means.

Abstract: A comprehensive and integrated point-of-care diagnostic system which consists of biosensors such as stethoscope front-recorder device, a blood pressure monitor, a spirometer, a pulse oximetry, a thermometer, a handheld ultrasound machine, a blood glucose meter, an otoscope and an ophthalmoscope. The biosensors collect data from a user or patient. The data collected is then transferred to a mobile device which then transfers the data to health management server for analysis and notifications.

Abstract: A method of measuring a pulse wave velocity difference in a mobile device includes: obtaining electrocardiogram (ECG) information of an object through a first electrode that contacts a first surface of the object and is included in the mobile device and a second electrode that contacts a second surface of the object and is included in the mobile device; obtaining blood flow change information of the first surface and the second surface by using a first optical sensor that contacts the first surface and is included in the mobile device and a second optical sensor that contacts the second surface and is included in the mobile device; obtaining pulse wave velocity information to the first surface and pulse wave velocity information to the second surface based on the obtained ECG information and the obtained blood flow change information of the first surface and the second surface; and measuring pulse wave velocity difference information based on the pulse wave velocity information to the first surface and the se

Abstract: A sensor assembly comprises an optical fiber having a sensing fiber portion that comprises at least one Fiber Bragg Grating. Further, the sensor assembly comprises a sensing body having body ends coupled to the fiber at opposite axial sides of the sensing fiber portion. Optionally, the optical fiber is arranged within a capillary, and the body ends of the sensing body are attached to the capillary, at opposite axial sides of the sensing fiber portion. The capillary may be filled with glue for attaching the optical fiber to the capillary.

Abstract: A blood pressure monitor comprising a main engine and a cuff is provided. The main engine has a housing, a pump which is disposed in the housing, and a plurality of first venting pipes. A plurality of first through-holes is formed on the housing to gas-communicate with the pump. The cuff has a gasbag and a plurality of gas nozzles. The gas nozzles extend from the gasbag to connect with the first venting pipes. Gas generated from the pump inflates the gasbag through the first through-holes, the first venting pipes, and the gas nozzles.

Abstract: A non-invasive blood pressure monitor has a blood pressure cuff and a wireless blood pressure determination unit. The wireless blood pressure determination unit automatically determines the fastest method for measuring blood pressure of a patient based on an initial blood pressure measurement made while inflating the cuff.

Abstract: A pulse wave sensor includes a light sensor unit arranged to irradiate a living body with light from a light emitting unit and to detect reflected light or transmitted light from the living body by a light receiving unit, so as to generate a current signal corresponding to received light intensity, a pulse drive unit arranged to turn on and off the light emitting unit at a predetermined frame frequency and duty, a transimpedance amplifier arranged to convert the current signal into a voltage signal, and a mounting determination unit arranged to perform mounting determination by comparing an OFF voltage signal obtained by the transimpedance amplifier during an OFF period of the light emitting unit with a predetermined first threshold voltage.

Abstract: Measuring a neural response to a stimulus comprises applying an electrical stimulus, then imposing a delay during which the stimulus electrodes are open circuited. During the delay, a neural response signal present at sense electrodes is measured with a measurement amplifier, while ensuring that an impedance between the sense electrodes is sufficiently large that a voltage arising on the sense electrode tissue interface in response to the stimulus is constrained to a level which permits assessment of the neural response voltage seen at the sense electrode. For example the input impedance to the measurement amplifier (ZIN) can be Z IN > Z C ? ( V S ? ? 1 - V S ? ? 2 ) V E , where ZC is the sense electrode(s) constant phase element impedance, Vs1?Vs2 is the differential voltage arising on the sense electrode tissue interface, and VE is the neural response voltage seen at the sense electrode.

Abstract: A method for vector analysis of an electrocardiogram for assessment of risk of sudden cardiac death includes receiving data about electrical activity of heart of a subject recorded on electrocardiogram device, generating a vector cardiogram based on the data, analyzing the vector cardiogram to determine arrhythmogenic right ventricular dys-plasia/cardiomyopathy to identify a presence of a micro-scar in a three-dimensional vector loop of the vector cardiogram, determining a risk of SCD for the subject based on the identification of the presence of a micro-scar, and storing the risk in a database.

Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.

Abstract: A method for determining electrophysiology properties of tissue comprising acquiring electrical signal data from a plurality of electrodes (130) of one or more catheters, determining at least one electrode clique from the plurality of adjacent electrodes (136), computing local conduction velocity vectors for the at least one electrode clique (138), determining at least one catheter orientation independent indicator from which to classify an arrhythmia source based on one or more of an angular dependence parameter associated with a flow field of the local velocity conduction vectors, an eccentricity parameter reflecting the uniformity of local conduction velocity, and divergence and curl-like sums or closed path integral parameters associated with the local velocity vectors, and displaying a rhythm classification responsive to catheter movement thereby facilitating identification of types and causes of arrhythmia disorders.

Abstract: An electrode for cardiac signal sensing includes an intermediate layer, an iridium-containing layer, an iridium oxide layer, an insulating polymer layer, and a conductive layer formed on a flexible polymer substrate. The intermediate metal layer has a first portion and a second portion, and is formed on the conductive layer. The iridium-containing layer includes at least 50 wt. % iridium and has a first portion and a second portion, and is formed on the first portion of the intermediate metal layer. The iridium oxide layer is formed on the first portion of the iridium-containing layer. The insulating polymer layer is formed on the second portion of the intermediate metal layer and the second portion of the iridium-containing layer. The iridium-containing layer is not formed on the second portion of the intermediate metal layer; and the iridium oxide layer is not formed on the second portion of the iridium-containing layer.

Abstract: The present disclosure is related to a play control method, apparatus and terminal. The method comprises: acquiring brain wave information of a user; and controlling an electronic device based on the brain wave information. When the embodiments of this disclosure are applied, by acquiring brain wave information of a user and controlling an electronic device based on the brain wave information, the state of the user can be reflected through the brain wave information; accordingly, effective control of the user's needs can be realized through the brain wave information without any triggering operation by the user, thereby enhancing the user experience and improving the intelligence level of electronic device.

Abstract: An implantable device includes one or more electrodes to sense an electrical signal from a brain and a waveform analyzer to identify a half wave in the electrical signal; determine an amplitude and a duration of the half wave; determine if the amplitude satisfies a half wave amplitude criterion defined by a set of amplitude parameters comprising a minimum half wave amplitude and a maximum half wave amplitude; determine if the duration satisfies a half wave duration criterion defined by a set of duration parameters comprising a minimum half wave duration and a maximum half wave duration; and identify the half wave as a qualified half wave when the half wave amplitude criterion and the half wave duration criterion is satisfied. A neurological event may be detected based on one or more qualified half waves and electrical stimulation therapy may be delivered to the brain in response to the detection.

Abstract: Wearable devices are provided including electrical contacts to detect voltages or other biosignals when mounted to the skin of a wearer. The impedance between a pair of the electrical contacts can be detected and the device operated based on the detected impedance. The device can detect an electrocardiogram or other biopotentials using the electrical contacts if the detected impedance falls below a specified threshold. The device could indicate that the detected impedance is below the specified threshold, e.g., such that a wearer could contact one of the electrical contacts with a finger to allow detection of an electrocardiogram between the arms of the wearer. The device could indicate that the detected impedance remains greater than the specified threshold, e.g., such that a wearer could re-mount the wearable device to improve the electrical connection between the electrical contacts and the wearer's skin.

Abstract: Electrode arrays have a plurality of electrodes. These arrays may have any combination of the following improvements. The arrays may have features that enable easier electrical connections and reduced bending stiffness by having a stop region and a torsion relief region, respectively. The arrays may have a shielding feature that may reduce electrical interference. The arrays may come in pairs that are designed to simplify measurements of electric signals of bilateral organs and tissues, such as eyes and ears.

Abstract: The present invention relates to an external standard reference system of a type inserted into the coil of a human magnetic resonance imaging equipment, and more specifically, to a system capable of analyzing metabolic components (quantity of metabolites) in a human body without an error and a limited range using an external standard reference analysis method, in order to enhance accuracy of diagnosis by utilizing magnetic resonance spectroscopy of the human magnetic resonance imaging equipment. A system for evaluating performance of magnetic resonance spectroscopy includes an outer container for inserting an RF coil and provided with a plurality of holes; a plurality of inner containers arranged to be inserted into the plurality of holes respectively and capable of being filled with metabolites different from each other in at least a type or a concentration; and a frame for fixing a head of an object arranged inside the outer container.

Abstract: An MRI prep scan acquires plural sets of echo signals at a plurality of cardiac time phases which are mutually different from each other for each slice and used to generate a plurality of respectively corresponding prep images. Reference information is acquired and displayed for determining a first cardiac time phase and a second cardiac time phase on the basis of the prep images. The first and second cardiac time phases are set in response to an operator's specification. An imaging scan section for acquiring imaging echo signals by performing an imaging scan is performed upon each of the first and second cardiac time phases to acquire imaging echo signals. A first image is generated based on an echo signal of the first cardiac time phase and a second image is generated based on an echo signal of the second cardiac time phase. A differential image is acquired by calculating a difference between the first image and the second image.

Abstract: A method of high resolution electrical impedance imaging including using an array of sampling points defined by an electrode frame at a first position, wherein the electrode frame defines a relative displacement of sampling points; and using a different array of sampling points defined by the same electrode frame at a different, second position.

Abstract: A roll-detecting sensor assembly includes a coil extending along and disposed about an axis. The coil comprises one or more portions, with each portion defining a winding angle. At least one of the portions defines a winding angle that is substantially nonzero relative to a line perpendicular to the axis, whereby the projected area of the coil in an applied magnetic field changes as the coil rotates about the axis. As a result, the coil is configured to produce a signal responsive to the magnetic field indicative of the roll of the sensor about the axis. In an embodiment, at least one of the portions defines a winding angle that is at least 2 degrees. In an embodiment, at least one of the portions defines a winding angle that is about 45 degrees.

Abstract: The invention relates to a device for superimposing known patterns, characteristic of a region, on (real) images of said region. The device comprises, a memory in which patterns are stored, which are representative of a selected region, of known position and orientation with relation to a common reference and processing means, for determining a pattern representative of the selected portion in the memory, on receipt of the designation of at least one portion of an observed image of the selected region, taken at a selected angle and at least one representative attribute of said region, taking account of the attribute selected, then superimposing the determined pattern on the selected portion of the image taking account of the selected angle.

Abstract: A introducer is disclosed that includes an introducer sheath for introducing a catheter into a blood vessel at an insertion point, a plurality of electrodes on the introducer sheath, a flush line coupled to the introducer sheath including a proximal end and a distal end. In addition, the introducer includes an impedance assessment unit coupled to the flush line between the proximal end and the distal end and electrically coupled to the electrodes. The impedance assessment unit is configured to inject a predetermined current or voltage into a first of the plurality of electrodes and measure a resulting voltage or current, respectively, from a second of the plurality of electrodes.

Abstract: The disclosure relates to a method and apparatus for controlling a display device. Aspects of the disclosure provide a method controlling a display device. The method includes detecting an object on a pad; determining whether the object is a user; determining an identity of the user when it is determined that the object is the user; determining at least one user preference associated with the user based on the identity of the user; and transmitting, to the display device, at least one instruction to display information associated with the at least one user preference. When determining the identity of the user, the method includes determining that the user is a person.

Abstract: The wearable measurement device includes a mounting part for mounting the device to a human body, a variation detection part detecting a variation in distance from a predetermined portion of the human body, a posture detection part detecting a posture of the variation detection part in the case where the device is mounted to the human body through the mounting part, and a measurement part measuring the number of predetermined motions based on the variation detected by the variation detection part and the posture detected by the posture detection part. The variation detection part includes a light emitting unit and a light receiving unit, makes the light emitting unit emit light and the light receiving unit detect reflection light reflected at a predetermined portion, detects a distance from the predetermined portion and outputs an electric signal (voltage or current) in accordance with the detected distance at a predetermined sampling cycle.

Abstract: Systems and methods for detecting onset, presence, and progression of particular states, including intoxication, include observing eye movements of a subject and correlating the observed movements to known baseline neurophysiological indicators of intoxication. A detection system may record eye movement data from a user, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not intoxication or impairment is present. The detection system may alert the user to take corrective action if onset or presence of a dangerous condition is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device. An interactive application may be provided on a user device to provoke the desired eye movements during recording.

Abstract: Provided is a method and apparatus for assisting spasticity and clonus evaluation using an inertia sensor, the apparatus including an acquirer configured to acquire a measured value from an inertia sensor attached to an object, a calculator configured to calculate an angle of a joint of the object based on the measured value, and a processor configured to evaluate a spasticity and a clonus based on the angle of the joint.

Abstract: This application provides an identification method and device, and relates to the field of wearable devices. The method comprises: acquiring a first heartbeat propagation signal and a second heartbeat propagation signal separately from a target limb of a body; and identifying whether the target limb is a left limb or a right limb at least according to the first heartbeat propagation signal and the second heartbeat propagation signal. The method and device can implement automatic identification of left and right limbs, simplify configuration steps, and improve user experience.

Abstract: A monitoring system and method tracks a patient's position over time and ensures that proper turning or other manipulation is done within the time prescribed. Preferably, the techniques herein continuously monitor patient position and alert medical or other personnel of the need for turning or other patient manipulation. The system may be implemented within a medical or other care facility, or within a patient's home.

Abstract: The present invention provides an information processing device that, when the height of a reference plane of a bed is being set on a screen using a setting unit, clearly indicates, on a captured image, a region that is located at the height of the reference plane, based on depth information that is included in the captured image. It thereby becomes possible to readily set the reference plane of the bed, which serves as a reference for behavior of a person being watched over. Thereafter, the information processing device detects the behavior of the person being watched over, by determining whether the positional relationship between the reference plane of the bed and the person being watched over satisfies a predetermined condition.

Abstract: A respiratory effort sensing belt that incorporates a PVDF transducer is constructed such that the transducer is contained within an elastic, moisture impervious plastic envelope and affixed to the envelope are a pair of connectors adapted to receive opposed ends of a body-encircling, single-use band and which provide the ability to adjust belt tension. Because of the construction of the sensor module, it may be sterilized for reuse.

Abstract: Systems and methods for determining the hearing status of a person are described that involve administering more than one type of a hearing test in the context of a game or games.

Abstract: Method and apparatus for providing calibration of analyte sensor including applying a control signal, detecting a measured response to the control signal, determining a variance in the detected measured response, and estimating a sensor sensitivity based on the variance in the detected measured response is provided

Abstract: This patent is a combined non-invasive method of monitoring glucose level. Monitoring the concentration of glucose level in human blood and tissue was developed by a combined non-invasive technique. This combined method includes skin temperature and pulse wave measurement. All these measurements are used to calculate the blood glucose level. This method also can be used to measure the diabetes related damage of micro arterial.

Abstract: A sensor that may be used to detect the presence, amount, and/or concentration of an analyte in a medium within an animal. The sensor may include a sensor housing, an indicator element embedded within and/or covering at least a portion of the sensor housing, and a membrane over the indicator element. The membrane may reduce indicator element deterioration by preventing immune cells, such as white blood cells, from contacting the indicator element, substantially prevent transmission of light of at least a specified wavelength or range of wavelengths through the membrane, and/or permit the analyte to pass through to the indicator element. The membrane may be an opaque diffusion membrane. The sensor may include a foil. The foil may block light and/or reduce indicator element deterioration. The membrane may reduce oxidation of the indicator element.

Abstract: A biological fluid collection device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to transfer the blood sample to a point-of-care testing device or a biological fluid separation and testing device. After transferring the blood sample, the biological fluid separation and testing device is able to separate the plasma portion from the cellular portion and analyze the blood sample and obtain test results.

Abstract: Cognitive function testing. At least some of example embodiments are methods including performing a cognitive function test on a patient without calibrating pupil position of the patient. The performing may include: causing a visual cue on a computer screen in front of the patient to move in a predetermined pattern; reading frames from an eye camera that captures images of an eye of the patient while the visual cue moves on the computer screen and the patient visually tracks the visual cue; determining pupil position within the frames; correcting offsets between the stimulus data and the pupil position data; translating the pupil position data from a coordinate space of the eye camera to a coordinate space of the stimulus data; and generating a test score being the cumulative distance between the stimulus data and pupil position data for each corresponding point in time.

Abstract: A method and system for generating a personalized health management recommendation for a user. During operation, the system obtains first physiological data generated by a wearable device worn by the user that indicates a physiological condition of the user. The system then generates a prediction model for the user based on the first physiological data. Next, the system obtains real-time physiological data generated by the wearable device. The system may generate a prediction by analyzing the real-time physiological data to determine whether the user's physiological condition exceeds a threshold parameter according to the prediction model. Upon determining that the threshold parameter has been exceeded, the system may select a recommendation and send the recommendation message to the user's mobile device.

Abstract: A social intimacy determining method includes detecting electrocardiogram (ECG) data from at least two subjects; detecting heart rhythm pattern (HRP) data from ECG signals of the two subjects; and determining a relationship (intimacy) between the two subjects by comparing the FIRP data of the two subjects.

Abstract: Disclosed are techniques for determining a severity of motion disorder symptoms by receiving sensor data from one or more sensors, determining that the sensor data represents one or more activities of daily life (ADLs) of a user, assigning one or more probabilities to the one or more determined ADLs, each probability of the one or more probabilities indicating a confidence level that the sensor data represents a corresponding ADL, and providing the sensor data and the one or more probabilities to a motion disorder symptom scoring module that generates one or more scores for the one or more determined ADLs based on the sensor data, each score of the one or more scores indicating the severity of the motion disorder symptoms for a corresponding ADL, and combines the one or more scores and the one or more probabilities to generate an aggregated severity score for the motion disorder symptoms.

Abstract: A computer based method and system forms measurements of brain function and predictions of a likelihood for memory impairment via the use of cameras, including a near-infrared (NIR) spectroscopic device and a camera capturing images in the Red-Green-Blue (RGB) spectrum. The device acquires from a subject measurements of ions, molecules, or combinations thereof at more than one moment in time, as well as amplitude and timing of blood pulsations. Based on the measured molecule or ion concentration, flow, and so forth, a processor assesses the probability of a neuron to form an action potential. Formation of an action potential increases the probability that the subject individual will create a memory.

Abstract: The present invention is a system for continuous real-time monitoring of a patient's breath chemistry comprising a plurality of components, including a self-condensing pH sensor distally mounted on a catheter, a pepsin sensor distally mounted on a catheter either separately or in combination with a self-condensing pH sensor, a transmitter with hydration sensing circuitry, and processing receiver/data recorder that can be a smart phone, tablet, TV, watch, wearable device, or custom designed device with wireless capability and utilizing an APP (application) that displays and records the pH and/or pepsin collected data.

Abstract: A method is provided for generating images using a MRI system. The method includes one or more acts below. First, the MRI system applies a pulse sequence to obtain a first set of blood oxygenation level dependent (BOLD) MRI images of a pregnant subject during a first time period. The MRI system then applies the pulse sequence to obtain a second set of BOLD MRI images of the pregnant subject during a second time period. The MRI system automatically extracts one or more regions of interest that include a placenta of the pregnant subject in the first and second sets of BOLD MRI images. The MRI system obtains BOLD signal changes in the one or more regions of interest based on the first and second sets of BOLD MRI images. The MRI system generates, based on the BOLD signal changes, a map indicating placental oxygen transport.

Abstract: Methods and compositions are provided for the analysis of skin surfaces to determine the presence of neoplastic tissue. In the methods of the invention, a composition comprising a florescent probe that binds to a specific neoplasia associated marker is applied topically to the area of interest. After topical administration, the probe preferentially binds to markers associated in neoplastic lesions in situ, which binding is detected with a compact illumination unit that provides illumination at a wavelength appropriate for image acquisition. The illumination unit comprises a light source and fiber optic bundle to direct the light towards the area of examination. A detection unit is used to capture and record an image of the area of investigation. The detection unit may be a digital camera, film camera, etc. A mapping module may also be provided to catalogue the site of examination.

Abstract: Methods and systems for measuring muscle sarcomere length are disclosed. In an embodiment, a method comprises illuminating a set of muscle fibers with electromagnetic radiation, measuring an intensity of the electromagnetic radiation as reflected from the muscle fibers, the measuring occurring as a function of wavelength, determining wavelengths corresponding to maximums of reflected intensity, and correlating the determined wavelengths with respective muscle sarcomere lengths. In an embodiment, a system comprises an illumination source system for illuminating the set of muscle fibers with electromagnetic radiation, and an analyzer for measuring the intensity of the electromagnetic radiation as reflected from the muscle fibers.

Abstract: A nonlinear diagnostic analysis apparatus includes at least one transducer connected to an examinee's head for transmitting a transmission frequency and feeding back a reflection frequency from the examinee's head through the transducer, a detection unit connected to the transducer to allow the transducer to transmit the transmission frequency and receive the reflection frequency, and a control unit connected to the detection unit. The control unit has a computing unit for computing the reflection frequency and comparing the transmission frequency and reflection frequency to obtain detected information, an essential oils database containing essential oils information and essential oils using methods, such that after the computing unit computes the reflection frequency, the detected information and essential oils database are compared to select suitable type and dosage of the essential oil, and a screen for displaying the detected information and the suggested type and using method of the essential oil.

Abstract: A computer-implemented system and related method of reporting glucose information for a user of a diabetes management device are presented here. An embodiment of the method obtains input data for the user of the diabetes management device, and identifies a tracked glycemic response event. One or more recommended glycemic control parameters are calculated based on an analysis of the obtained input data. The glycemic control parameters are calculated to extend a time period during which the user remains within a target glucose range following the tracked glycemic response event. The method continues by generating an output message that includes at least some of the recommended glycemic control parameters, and delivering the generated output message to a user device operated by the user of the diabetes management device.

Abstract: The challenge addressed by the invention is, in a case in which a consulter harbors a mistaken perception regarding the quality of his or her own sleep, to bring this to the attention of the consulter in a simple manner.

Abstract: A resuscitation system for use by a rescuer for resuscitating a patient, comprising at least two high-voltage defibrillation electrodes, a first electrical unit comprising circuitry for providing resuscitation prompts to the rescuer, a second electrical unit separate from the first unit and comprising circuitry for providing defibrillation pulses to the electrodes, and circuitry for providing at least one electrical connection between the first and second units.