Abstract: Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a retrieval end having one or more compressed states and an expanded state, the retrieval end adopting the expanded state when the retrieval end is deployed into a subject's internal body space, the retrieval end having a mouth through which an object can be passed into an interior space within the retrieval end when the retrieval end is in the expanded state, the mouth being adjustable between an opened state and a closed state; wherein when at least a portion of the retrieval end of the inner sheath is transitioned to a compressed state following capture of the object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.

Abstract: A clamping device for an external fixation system includes a post component having a yaw axis, a first clamp secured to the post component and rotatable about the yaw axis, and a second clamp secured to the post component and rotatable about the yaw axis relative to the first clamp. The device includes a tightening component configured in a manner that an action of tightening the tightening component simultaneously locks both the first and second clamps in a gripping arrangement and substantially eliminates their relative rotation about the yaw axis. Interdigitating components can be spaced apart by high spring rate biasing elements that so as to allow for smooth adjustment of the clamping device components relative to each other until the appropriate position is achieved and until after a sufficiently high clamping load has been applied.

Abstract: A method of limiting at least one degree of movement between a superior vertebral body and an inferior vertebral body of a patient includes advancing a distal end of a stabilization device into a pedicle of the inferior vertebral body. A proximal portion of the stabilization device is positioned such that the proximal portion limits at least one degree of movement between a superior vertebral body and an inferior vertebral body by contacting a surface of the superior vertebral body.

Abstract: A spinal construct is provided including a first fastener, a second fastener and a connector. Each fastener includes a first end and a second end configured for penetrating tissue. The connector has two ends. Each end of the connector includes an expandable member. The first end of each fastener is engageable to an expandable member of the connector to fix the fastener to the connector. The first and second ends of the connector are connected by a bridge. The spinal construct also includes securing members for attaching the connector to the fasteners. A method for treating a spinal disorder with the spinal construct is also provided.

Abstract: An adjustable rod for spinal corrective surgery is provided that includes a first elongate member and a second elongate member, each having rod portions couplable to one or more bone connecting elements and expansion portions slidably moveable with respect to one another. A plurality of holes in each expansion portion are alignable with one another to choose the length of the adjustable rod and a locking element is inserted through a pair of aligned holes to couple the first and second elongate members and secure or fix the length of the expandable rod.

Abstract: An osteosynthesis system comprising anchoring screws, wherein at least one of the anchoring screws comprises a bone anchoring element with a longitudinal axis AA, comprising a threaded anchoring rod prolonged at the end by a coupling head and a screw head for coupling a connecting element to the bone anchoring element, wherein the screw, comprises a body with a longitudinal axis BB traversed longitudinally by a channel featuring in the lower portion a receiving cavity for receiving the coupling head of the anchoring element, at least one connecting element designed to interconnect the anchoring screws, means of tightening the connecting element on each anchoring screw, a means of straightening the bone anchoring element in relation to the screw head during tightening, wherein the means of straightening are arranged to straighten the threaded rod of the bone anchoring element and place the former in the longitudinal axis BB.

Abstract: A system for replacing at least a portion of a natural facet joint includes a fixation member implantable in a vertebra, an inferior facet articular surface and an inferior strut which may be formed separately from the inferior articular surface. The inferior strut has a first end securable to the fixation member and a second end which may comprise a sphere with a hemispherical surface. An attachment mechanism may include a capture feature shaped to receive the second end of the inferior strut, and the mechanism may provide an adjustable configuration, allowing polyaxial adjustment between the inferior articular surface and the second end. A locking member may be actuated to exert force on the second end to provide a locked configuration. The system may further include a superior facet joint implant with a superior articular surface shaped to articulate with the inferior articular surface.

Abstract: A facet joint replacement system includes an inferior implant with an inferior articular surface, a superior implant with a superior articular surface, and an optional crossbar. The inferior implant and the superior implant are each polyaxially adjustably connected to fixation elements which anchor the implants to adjacent vertebrae. The optional crossbar may be polyaxially adjustably connected to bilateral implants. The system components may be provided in kits which provide components of various sizes and shapes. A set of surgical instruments may facilitate implantation of the facet joint replacement system by providing tools for bone preparation, trialing, implant insertion, implant alignment, and lock-out of modular interconnections.

Abstract: A surgical instrument configured to introduce a spinal fixation rod into a vertebral implant. When the spinal fixation rod is engaged with the surgical instrument and the surgical instrument is put into a retention configuration, the spinal fixation rod cannot be removed from the surgical instrument until the spinal fixation rod is properly oriented with respect to the surgical construct and the surgical instrument is released from the retention configuration. The surgical instrument includes a surgical instrument body, an actuator, an engagement assembly, and a transfer assembly that extends between the actuator and the engagement assembly. The surgical instrument can also be used as part of a method for introducing a spinal fixation rod or part of a kit for introducing a spinal fixation rod.

Abstract: Methods and apparatus for treating bones, including, in one or more embodiments, methods and apparatus for treatment of vertebral fractures that include a containment assembly for cement containment and/or a balloon assembly for maintaining vertebral height. A containment assembly comprising a containment jacket adapted to be deployed inside bone; and a dividing wall that separates the interior of the containment jacket into a proximal region and a distal region, the dividing wall having an opening for providing access to the distal region from the proximal region.

Abstract: Methods and apparatus for treating bones, including, in one or more embodiments, methods and apparatus for treatment of vertebral fractures that include an inflation device for cavity creation and an inflation and containment device for maintaining vertebral height and cement containment. Methods for treating a bone comprising: creating a cavity in the bone; inflating a containment jacket in the cavity; inflating a balloon within the containment jacket so that the balloon occupies a first portion of the containment jacket; introducing a first filler material into a second portion of the containment jacket, wherein the second portion of the containment jacket is not occupied by the balloon; removing the balloon from the containment jacket; and introducing a second filler material into the first portion of the containment jacket.

Abstract: A surgical implant which includes: a first anchoring portion comprising two first arms movable between an inserting position and an anchoring position, in which the first arms are spread apart so as to be anchored in a first bone; a second anchoring portion to be anchored in the second bone; and an intermediate portion connecting the first anchoring portion to the second anchoring portion. The intermediate portion comprises: a recess; and a first connecting portion and a second connecting portion that are remote from one another. Bringing the first connecting portion and second connecting portion closer together moves the first arms from the inserting position thereof to the anchoring position thereof.

Abstract: An anterior cervical plate assembly is characterized in that it comprises a base plate and fastener with a two-part locking mechanism. The locking mechanism includes a blocking plate that translates along a recess in the base plate to partially overlap a fastener, preventing back-out. The locking mechanism also includes a locking piece that extends through the base plate and has a rotational cam surface that causes the translation of the blocking plate.

Abstract: An orthopedic implant has a plate and bone screws. Configured bone screw pockets of the plate provide variable angling and positional locking of a received bone screw relative. Each bone screw includes distal threads, a neck, and a dual threaded head. The plate has a bone screw pocket on a distal end, a bone screw pocket on a proximal end, and a strut extending between the two bone screw pockets. The bone screw pockets are at least generally cup shaped for receipt of a bone screw. The lower periphery of the opening of each bone screw pocket has an arrangement of configured prongs with configured openings to receive threading on the underside of the dual threaded head of the bone screw. The prongs can preferably, but not necessarily, deform slightly and grab onto the threading of the bone screw head to lock the bone screw in the bone screw pocket. Each prong can act independently.

Abstract: Implant devices for the internal fixation of fractured bones, and more particularly to ankle plates for the tibia bone are disclosed and include an anterolateral tibia plate having an L-shaped body including a proximal portion defining a longitudinal axis, and a distal portion defining a traverse axis, and having a support bridge connected between the proximal portion and the distal portion. Implant devices disclosed also include an anterior tibia plate having an elongated first portion, a second portion that widens outward with respect to the elongated first portion, and a plurality of removable tabs attached to the outer edge of the second portion. Implant devices disclosed also include a medial tibia plate having an elongated shaft with a proximal portion and a distal portion. The distal portion is configured to extend proximate to a base of medial malleolus, and has a curvature with respect to a longitudinal axis defined by the elongated shaft. The distal portion may include a plurality of removable tabs.

Abstract: Implant devices for the internal fixation of fractured bones, and more particularly to ankle plates for the tibia bone are disclosed and include an anterolateral tibia plate having an L-shaped body including a proximal portion defining a longitudinal axis, and a distal portion defining a traverse axis, and having a support bridge connected between the proximal portion and the distal portion. Implant devices disclosed also include an anterior tibia plate having an elongated first portion, a second portion that widens outward with respect to the elongated first portion, and a plurality of removable tabs attached to the outer edge of the second portion. Implant devices disclosed also include a medial tibia plate having an elongated shaft with a proximal portion and a distal portion. The distal portion is configured to extend proximate to a base of medial malleolus, and has a curvature with respect to a longitudinal axis defined by the elongated shaft. The distal portion may include a plurality of removable tabs.

Abstract: A patella fracture fixation system includes a peripheral rim bone plate that is configured to be implanted along a parapatellar lateral approach. The bone plate can configured to minimize disruption of blood supply to the patella. The bone plate can be augmented with a Krackow suture pattern to assist in stabilization of a comminuted inferior pole.

Abstract: A volar distal radius plate includes a shaft and a head. The head includes a radial side that seats below the volar rim, and an ulnar side with two extending tabs that provide a buttress support to ulnar fragments from the volar rim. The tabs are contoured to be atraumatic to the overlying soft tissue. The tabs can be readily re-orientated to better approximate the volar rim and provide close support to the volar fragments. Each tab includes a single hole specifically sized to closely receive a K-wire in a fixed angle orientation, and which permits the K-wire to apply a bending load to a tab in situ to bend the tab about a lower recess between the tab and the remainder of the head. Therefore, the plate does not require a dedicated bender. The tabs can also accommodate sutures.

Abstract: A rib fixation system having a bone plate and mono-cortical bone screws adapted for affixation to a rib, the security of the system being enhanced by providing paired sets of screw-receiving openings, wherein the offset axis of each opening of the paired set is approximately ten degrees off from the normal axis in the transverse direction toward the longitudinal midline of the bone plate and is also approximately ten degrees off the normal axis in the longitudinal direction, with the offset axis of each opening in a paired set being turned toward the other opening in the paired set.

Abstract: Disclosed is a protector capable of stably joining between adjacent bones while providing a proper elasticity thereto. The protector includes an elastic member having a center part which is placed to cover a joint between adjacent bones, and a plurality of fixing members which are located at both end parts of the elastic member and are fixed to the bones.

Abstract: The present disclosure provides a fastener that has a body that has an axis. The body comprises a head portion and at least one body portion projecting from the head portion. The at least one body portion has an actuating surface portion and is arranged such that at least a part of the at least one body portion is urged away from the axis when an actuating member is received along the axis and urges against the actuating surface portion. The at least one body portion has a substantially flat surface portion facing away from the axis.

Abstract: An apparatus for distributing the load caused by the insertion of a fastening device into bony tissue is disclosed. In one embodiment, the apparatus comprises a crown having a plurality of protrusions. The protrusions may have any desired physical properties, and function to obtain purchase in the bony tissue. Preferably, the crown includes an opening that is selectively engageable with a spherical head of the fastening device. The opening preferably comprises a spherical curvature that allows the surfaces of the spherical head and the opening to maintain flush contact, even when the fastening device is inserted into the bony tissue at a non-orthogonal angle. When the fastening device is inserted into the bony tissue, the crown distributes the load over a wider section of the bone, allowing the bone to maintain its structural integrity.

Abstract: A laser device having a proximal end and a distal end spaced from the proximal end, the distal end configured to receive a fixation member to be affixed to a target surgical site. The laser device includes a laser source supported by the laser device body and capable of emitting a laser beam to the distal end, wherein the laser source is responsive to at least one input so as to selectively switch between an inactive configuration whereby the laser source does not emit the laser beam, and an active configuration whereby the laser source emits the laser beam.

Abstract: Described herein are devices and methods for limiting the torque applied to surgical screw during a surgical procedure in which a surgical screw is passed into a vertebra, such as, for example, a spinal fusion procedure. A surgical screw driver is configured to prevent an excessive amount of torque from being delivered to the vertebrae through a surgical screw. When an excessive amount of torque is delivered to the handle of a surgical screw driver, it is prevented from being transmitted to the surgical screw and is thus not delivered to the vertebrae. Excessive force in the form of excessive torque transmitted to a vertebrae may cause a fracture along with possible mispositioning or displacement of a surgical screw.

Abstract: Embodiments of the present invention generally relate to methods, devices, and systems for reducing a pigmentation of a skin of a patient. In some embodiments, freezing of the skin may be desirable to effect the hypopigmentation of the skin of the patient. Generally, embodiments may limit supercooling (or promote freezing) of the skin of the patient during a cooling treatment. In some embodiments, coupling fluids are provided to reduce a thermal contact resistance between a cooling treatment probe and the skin of the patient to improve cooling treatment. Optionally, a fluid carrier may be provided to help retain the coupling fluid at the treatment site. In some embodiments, the coupling fluid may include ice nucleating agents to promote ice crystal formation in the coupling fluid during cooling treatment. The ice crystal formation in the coupling fluid may progress into the skin to limit supercooling of the skin during treatment.

Abstract: A wireless ablation catheter assembly including an ablation catheter having a catheter body extending between a proximal end and a distal end with a magnetically-susceptible area defined along the catheter body between the proximal and distal ends. A magnetic field generator is configured to provide a magnetic field to the magnetically-susceptible area such that the magnetically-susceptible area dissipates heat. A method of ablation is also provided.

Abstract: A medical device that includes a support member, a heat insulator provided on at least a portion of a first surface of the support member, an energy output member configured to output energy, the energy output member provided on at least a portion of a first surface of the heat insulator, the output energy configured to treat biological tissue and a heat conductor provided on at least a portion of the first surface of the support member and contacting a second surface of the heat insulator, the second surface of the heat insulator opposite the first surface of the heat insulator, wherein a portion of the support member is located proximal than the energy output, and the energy output member is configured to transfer heat to the heat insulator, and wherein the heat conductor is configured to conduct the heat from the heat insulator to the support member.

Abstract: A method for killing or damaging cancerous cells in a living body comprising introducing glucose or other organic material as a biasing component into heating cancerous cells for purposes of destroying the cancerous cells with a second method of heating, such as by bombardment of energy from an external electromagnetic source, so as to raise the temperature of the tumor or cancerous cells to a degree that they are damaged or expire.

Abstract: This document provides methods and materials involved in treating hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), heart failure (e.g., congestive heart failure), or kidney disease (e.g., chronic kidney disease). For example, methods and materials involved in administering one or more sympatholytic agents to a patient to identify the patient as having an elevated baseline level of sympathetic nerve activity and treating the identified patient with a sympatholytic therapy to reduce the symptoms of hypertension (e.g., resistant hypertension), heart failure (e.g., congestive heart failure), or kidney disease (e.g., chronic kidney disease) are provided.

Abstract: Controlling a level of electrosurgical energy provided to tissue based on detected arcing patterns or impedance changes. The drag force imposed on an electrode or blade of an electrosurgical instrument may be controlled by adjusting the level of electrosurgical energy based on the arcing patterns or impedance changes. The arcing patterns or impedance changes may be detected by sensing and analyzing voltage and/or current waveforms of the electrosurgical energy. The current and/or voltage waveform analysis may involve calculating impedance based on the voltage and current waveforms and calculating changes in impedance over time. The waveform analysis may involve detecting harmonic distortion using FFTs, DFTs, Goertzel filters, polyphase demodulation techniques, and/or bandpass filters. The waveform analysis may involve determining a normalized difference or the average phase difference between the voltage and current waveforms.

Abstract: An electrosurgical system includes an electrosurgical probe connected to a control console, wherein the probe is capable of coagulating and ablating tissue depending on a selected operating mode. Before operating the system, probe-specific data stored in a memory device associated with the probe is read by a processing device in the console. The data includes source impedance values specific to a coagulation or cutting mode of operation. A constant duty cycle value for a modulated cutting mode also is provided. Depending on the operating mode selected, an RF generator adjusted to have a predetermined source impedance value provides a voltage value to the probe. During the duty-cycled mode, the RF generator generates an instantaneous voltage value output for a duty cycle portion that is less than 100% of a time period, which value is no less than a maximum continuous average voltage value for the electrosurgical probe.

Abstract: Systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller capable of being configured to apply voltages to independently selected subsets of electrodes and capable of generating at least one control signal to maintain the temperature near an electrode head within a desired range of values. Electrode clamp devices are also disclosed for generating electric fields to drive irreversible electroporation while modulating temperature to elevate the irreversible electroporation threshold utilizing a variety of means such as cooling fluid or solid state thermoelectric heat pumps.

Abstract: A tool (16) for the coagulation and dissection of biological tissue including a counter-bearing (35) that has at least one recess (37) open toward the outside and/or one or more hollow chambers (63). The recess (37) or the hollow chamber (63) is configured to provide a force/path elasticity characteristic curve with a plateau-like region II, V, during compression and reexpansion. The path section x in which the elasticity characteristic curve indicates the plateau II, IV preferably is as long as the tissue to be dissected is thick, and is, for example, in the range of 0.2 to 1.5 mm. As a result, the force exerted on the tissue during the cutting operation remains substantially constant in the effective work region.

Abstract: A forceps is provided and includes a housing having a shaft. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. One or both of the first and second jaw members is movable relative to the other jaw member from a clamping position to an open position. A resilient member operably couples to at least one of the first and second jaw members. The resilient member is configured to bias the first and second jaw members in the clamping position and provide a closure force on tissue disposed therebetween.

Abstract: Bipolar electrosurgical instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes an outer housing, and an inner tissue engaging surface corresponding to the inner tissue engaging surface of the opposing jaw. The instruments includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The jaws include asymmetrical electrodes disposed on the inner tissue engaging surfaces. A first contact region of the electrode has a greater surface area than that of the second contact region. During resection procedures wider electrodes impart improved sealing energy to the patient-side vessel while providing sufficient energy to resected tissue to effect hemostasis.

Abstract: Systems and methods for tissue ablation. Systems include needles with deployable filaments capable of producing asymmetrical offset lesions at target volumes, which may include a target nerve. Ablation of at least a portion of the target nerve may inhibit the ability of the nerve to transmit signals, such as pain signals, to the central nervous system. The offset lesion may facilitate procedures by directing energy towards the target nerve and away from collateral structures. Example anatomical structures include lumbar, thoracic, and cervical medial branch nerves and rami and the sacroiliac joint.

Abstract: Methods and systems for spinal radio frequency neurotomy. Systems include needles capable of applying RF energy to target volumes within a patient. Such target volumes may contain target medial branch nerves along vertebrae or rami proximate the sacrum. Such procedures may be used to ablate or cauterize a portion of the targeted nerve, thus blocking the ability of the nerve to transmit signals to the central nervous system. Disclosed needles may be operable to asymmetrically, relative to a central longitudinal axis of the needle, apply RF energy. Such asymmetry facilitates procedures where a tip of the needle is placed proximate to anatomical structures for location verification. Then RF energy may be applied in a selectable direction relative to the needle tip to ablate volumes that include the targeted medial branch nerves or rami, thus denervating facet joints or the sacroiliac joint, respectively, to relieve pain in a patient.

Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

Abstract: Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, monopolar neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such monopolar neuromodulation is performed bilaterally.

Abstract: A method for the treatment of a patient for the purpose of lowering blood pressure and/or treating other medical conditions such as cardiac arrhythmias. A catheter having an ablation element is placed inside the body of a patient and is directed to a targeted location either on in the abdominal aorta where the right or left renal arteries branch from the aorta at or near the superior junction or ostia or on the inside of the inferior vena cava near the junction with the right renal vein or in the left renal vein at a position spatially near where the left renal artery branches from the abdominal aorta. Catheters designed for use in the method where these targeted locations are also disclosed and claimed.

Abstract: Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

Abstract: Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller configurable to apply voltages to an independently selected subsets of electrodes, such that voltages of one polarity are applied to a multiplicity of electrodes on a first medical device and voltages of the opposite polarity to a multiplicity of electrodes on a second medical device. The first and second medical devices can be epicardial catheters positioned such that their opposing distal tips are approximately aligned and whose segments with electrodes collectively wrap around the pulmonary veins.

Abstract: A flexible tip electrode for an ablation catheter is disclosed. The catheter includes a catheter body and a hollow elongate tip electrode disposed at a distal end of the catheter body. The electrode includes a sidewall provided with one or more elongate gaps extending therethrough. The one or more elongate gaps providing flexibility in the sidewall for bending movement of the tip electrode relative to a longitudinal axis of the catheter body.

Abstract: A system and method involving an electrode system can include a flexible shaft.

Abstract: Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage pulses to drive irreversible electroporation for minimally invasive transurethral prostate ablation. In one embodiment, a switch unit is used to modulate and apply voltage pulses from a cardiac defibrillator, while in another, the system controller can be configured to apply voltages to an independently selected multiplicity or subsets of electrodes. Devices are disclosed for more effective DC voltage application including the infusion of cooled fluid to elevate the irreversible electroporation threshold of urethral wall tissue and to selectively ablate regions of prostate tissue alone.

Abstract: A microwave ablation system includes a generator including a first energy source, a second energy source and a diplexer, the diplexer multiplexes a first energy from the first energy source and a second energy from the second energy source. The system also includes a cable including a center conductor and an outer sheath where the multiplexed energy is transmitted through the center conductor. In addition an antenna is provided that is operable to receive the multiplexed energy from the center conductor and to deliver the multiplexed energy to a region of tissue. The outer sheath acts as a return path of the second energy to the second energy source. A sensor is also provided that measures at least one parameter of the second energy generated by the second energy source and the second energy returned from the region of tissue.

Abstract: System for enhancing the optical transparency of biological tissue covered by a surface permeability barrier of tissue, involving the delivery of a clarifying agent to the target biological tissue to alter the attenuation characteristics of the target biological tissue.

Abstract: Devices and methods are provided for indicating treatment efficiency by illuminating a signal onto surrounding tissue. The signal may be dynamic and is configured to indicate specific parameters of the treatment, the device and the patient. Various signal features may denote different parameters. Devices and methods are provided for maintaining a fiber tip effective throughout a treatment procedure by regenerating or replacing the tip. Devices and methods are provided for controlling emission from bended fibers. Cordless configurations of laser treatment devices are also provided.

Abstract: Disclosed herein are methods, compositions and tools for repairing, replacing or otherwise treating bone ligaments using devices designed from patient-specific information, including without limitation, surgical alignment instruments that have a surface that conforms to at least a portion of a patient's bone, cartilage or other component of the joint or ligament being treated.

Abstract: A system for displaying characteristics of target tissue during an ablation procedure is provided that includes an electronic control unit (ECU) configured to receive data regarding electrical properties of the target tissue for a time period. The ECU is also configured to determine a value responsive to the data and indicative of at least one of a predicted depth of a lesion in the target tissue, a predicted temperature of the target tissue, and a likelihood of steam pop of the target tissue for the time period. The system further includes a display device operatively connected to the ECU. The display device is configured to receive the value and display a visual representation indicative of at least one of a predicted depth of a lesion in the target tissue, a predicted temperature of the target tissue, and a likelihood of steam pop of the target tissue for the time period.