Abstract: A compact mechanical pump is provided. The pump is adjustable between a compact form and an expanded form, where the pump can be reduced to a compact form for ease of portability and storage and to the expanded form for use as a pump.

Abstract: A multiple intravenous line retention system includes a flexible panel having a top side, a bottom side, a first end and a second end. The panel has a length from the first end to the second end that is greater than 3.0 inches and less than 11.0 inches. The panel has a width from a first lateral edge to a second lateral edge is less than 1.0 inches. The panel is comprised of a flexible material. A mount is attached to the top side of the panel and extends upwardly therefrom. The mount removably receives a plurality of intravenous lines. A coupler is attached to the panel and couples the panel to a patient receiving the intravenous lines.

Abstract: An infusion adapter for connection with an infusion fluid container includes a connection portion including an anchor component for connecting to an injection port of the infusion fluid container, and a first port adapted for connection with a syringe assembly containing a medication fluid. The first port is in fluid communication with the connection portion. The anchor component is configured to securely connect the infusion adapter to the infusion fluid container to substantially prevent disconnection of the infusion adapter from the infusion fluid container once the infusion adapter is connected to the infusion fluid container.

Abstract: An infusion set includes a first infusion line set that forms a first infusion line with an injection port; and a connector including a male connector end that is insertable into the injection port, a female connector end to which a second infusion line can be connected, a flow channel, and a partition. The injection port and the connector are configured such that, when the male connector end of the connector is inserted into the injection port, the flow channel of the connector is divided by the partition into an in-flow channel configured to let in a liquid from the injection port in the first infusion line and an out-flow channel configured to let out the liquid that has entered the in-flow channel to the injection port.

Abstract: Systems, apparatuses, kits, and methods may provide a substance. A carrier apparatus may include a reservoir to hold a payload, a sensor to detect a target in a subject and generate data corresponding to the target, a processor to allow the payload to be accessible from the reservoir based on the data, and/or a biocompatible carrier composition to hold the reservoir, the sensor, and/or the processor. The reservoir may include a placebo reservoir, a medication reservoir, a diagnostic reservoir, and/or a modification reservoir. The payload may be made available based on a diagnosis, a detection of a target in a body, a level of the target in the body, and/or a context in which the carrier apparatus is deployed. The carrier apparatus may also include a wireless rechargeable battery to power a component of the carrier apparatus. The carrier apparatus may provide diagnostic and/or therapeutic functionality.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.

Abstract: A life maintenance mode named as the third type of life maintenance mode, includes decomposing inspection items of clinical diagnosis into a series of individual automatically measured and computed indicators of life condition data, popularized into people's daily life and work to be practiced continuously producing continuous diagnosis and inspection analysis report and trend; performing active control of the change of the life condition data by senior independent consciousness of cerebral cortex with the automatically measured and computed life condition data to serve as a quantitative traction device for treatment, rehabilitation, and health and longevity; predict and prevent the occurrence and development of diseases on the basis of the produced inspection analysis report and trend; automatically sending messages to remind a patient to check the treatment behaviors on the basis of doctor's advices and prescriptions in the track record of medical treatment, and providing an automatic no-response alarming s

Abstract: Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.

Abstract: A medicament delivery device is presented having a housing with a distal and a proximal end, the housing being adapted to receive a medicament container with a delivery member or with a connectable delivery member for delivery of a medicament. The device also has a drive mechanism arranged to act on a plunger rod, which plunger rod in turn is arranged to act on the medicament container for providing automatic delivery of the medicament and a hold-release mechanism interactively connected to the drive mechanism for releasing the drive mechanism from a biased position. A delayable signal generating mechanism generates an audible and/or tactile and/or visual signal indicating that the medicament has been completely delivered, which delayable signal generating mechanism is operably connected between said pre-tensioned drive mechanism and said plunger rod.

Abstract: A medicine injection device comprises a cartridge having a cartridge barrel and a plunger having a plunger shaft slidable within the cartridge barrel. The cartridge may have, e.g., a pre-filled medicine. The medicine injection device further comprises a body having a proximal end, a distal end, and a cavity in which the cartridge barrel is disposed. The proximal end of the body may optionally form a finger grip. The medicine injection device further comprises a plunger locking mechanism attached to the proximal end of the body. The plunger locking mechanism comprises a member with an aperture slidably engaged with the plunger shaft. The locking mechanism is configured for preventing the plunger from being removed from the cartridge barrel. For example, the plunger shaft may include a locking stop, e.g., a flange, that engages with the aperture in an interference arrangement.

Abstract: The present invention relates to an injection device for delivering set doses of a liquid drug to a user. The injection device has a scale drum for displaying the set dose, which scale drum is helically guided in a housing. The scale drum is thus rotational in relation to the housing between a zero position and a set position for displaying the set dose. Further, a needle cannula secured to a hub is mounted in an axially movable manner. The axial movement of the hub is generated by a spring. A blocking mechanism interacting between the scale drum and hub controls the axial movement of the hub such that the needle cannula automatically retracts from the skin of a user in response to the scale drum reaching the zero position.

Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

Abstract: A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a lock collar and a device shield biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. With the removal of a needle shield assembly comprising rigid and soft needle shields, the lock collar and device shield are free to move proximally along the syringe neck and interact with a syringe step down area to activate the device. As the device moves proximally, retention arms of the device shield interact with the syringe step down, causing the arms to deflect radially outwards to disengage from the lock collar triggering the device shield to move from a first position to a second position.

Abstract: Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.

Abstract: A medical apparatus which comprises a sharpened outer cannula and a blunt inner cannula slidingly disposed within the outer cannula is configured to allow one-hand operation by user to operate the medical apparatus. The apparatus also contains a visual position indication system adapted to indicate the position of the inner cannula.

Abstract: Pressure conditioning systems for supplying insufflation gas to an open-ended body conduit such as a rectal cavity during a transanal minimally invasive surgery (TAMIS) procedure can reduce billowing of walls of the body conduit. A pressure conditioning system can include a pressure storage component, an accumulator, and a flow restrictor. The pressure storage component can include a variable volume reservoir that is biased to a relatively low volume state. The flow restrictor can include insufflation tubing with a restrictor plate having a relatively low diameter orifice. The pressure storage component, accumulator, and flow restrictor can be fluidly connected in various orders in series or as side branches from a gas flow conduit. Despite a pulsed or otherwise discontinuous insufflation gas flow and leakage and absorption from the body conduit, the pressure conditioning system can maintain a constant pressure within the body conduit.

Abstract: A dose counter includes a triggering unit having at least a first and a second trigger member thereon. The triggering unit is configured interact with the canister of a metered-dose inhaler when the canister moves in a longitudinal direction from a rest position to an activation position. A circuit assembly includes a substrate with at least a first and a second switch thereon. The first and second switches are configured to interact with the first and second trigger members when the canister moves from the rest position to the activation position. The circuit assembly includes a counting circuit that is configured to receive a signal from the first and second switches and to determine when the metered dose inhaler is activated.

Abstract: The present invention relates to an aerochamber for inhalation of medicinal products in aerosol for the treatment of respiratory ailments. The aerochamber includes a tubular body including a proximal end with a front cover adapted to mount a mask to cover a mouth and a nose of a patient; a distal end with a rear cover adapted to connect to a container with a pressurized pharmaceutical solution to be inhaled, the rear cover includes an annular wall including a hole that matches with an opening on the distal end; a translucent cap having a front wall, an inside wall, a cavity, an opening on the front wall, the translucent cap is placed on a section of the annular wall of the rear cover; an inhalation sensor housed on the cavity of the translucent cap.

Abstract: A hand-held, portable inhalator device is disclosed. The device has a mouthpiece with a chamber operatively coupled to a medication inlet and a fluid outlet. A valve is disposed about the fluid outlet and is configured to open when subjected to a first threshold level of positive pressure permitting egress of fluid from the chamber. A trigger is configured to dispense medication from a medication source through the medication inlet and into the chamber after a second threshold level of positive pressure is achieved within the chamber of the mouthpiece and maintained for a threshold period of time.

Abstract: A method of providing a gas flow for delivery to an airway of a subject, which includes the steps of generating a gas flow that facilitates respiration of the subject, receiving a selection of an adjustment from the subject for a property of the gas flow, and making the selected adjustment to the gas flow if the gas flow will remain within a predetermined range after the selected adjustment is made. The method also includes the step of declining to make the selected adjustment to the gas flow if the gas flow would not remain within the predetermined range after the selected adjustment.

Abstract: A method of estimating respiratory demand of a patient being administered flow therapy comprising: administering a gas flow rate to the patient through both nostrils using a flow therapy apparatus with a patient interface for each nostril, measuring a parameter associated with that nostril, the parameter being one or more of: respiratory demand of that nostril, indicative of respiratory demand of that nostril, or a parameter from which respiratory demand of that nostril can be derived, determining respiratory demand (or parameter indicative of respiratory demand) for the patient from the nostril parameter for each nostril.

Abstract: One aspect of the present disclosure relates to a system for providing non-invasive, high frequency ventilation to a neonate or an infant in need thereof. The system can include a tubing array, a vibration device, and a bifurcated cannula. The tubing array can be adapted to receive a flow of pressurized gas therethrough. The vibration device can be fluidly coupled to the tubing array and configured to generate and apply a jet of air to the flow of pressurized gas. The bifurcated cannula can be fluidly coupled to the tubing array and have independently movable first and second prongs that are sized and dimensioned for insertion into first and second nostrils, respectively, of the neonate or the infant.

Abstract: A cuffed tracheostomy tube has a sealing cuff 10, 10?, 100, 100? attached to a shaft 1, 1, 1? of the tube towards its patient end by a rear end collar 30, 55, 103 bonded with the outside of the shaft. In one embodiment the patient end collar 31, 31? is folded unattached around the patient end face 60, 60? of the shaft and is attached to the inside of the tube. When inflated, the cuff inflates slightly away from the patient end face to cushion the tip of the tube. In another embodiment the cuff 100 is formed integrally with the shaft 51. In a further embodiment the cuff 100? has an integral portion 102 of a soft material that forms a patient end extension of the shaft 1?.

Abstract: Devices and methods for preventing tracheal aspiration as described, where a cuff assembly having an inflatable member with an inflation tube fluidly coupled may be placed over a proximal end of an endotracheal tube or laryngeal mask and inserted into the patient trachea with the endotracheal tube or separately after the endotracheal tube has already been positioned. In either case, the inflatable member may be positioned distal (or inferior) to the vocal cords and proximal to the endotracheal balloon via a delivery instrument which automatically positions the balloon in proximity to the vocal cords.

Abstract: A facemask to abolish “difficult mask ventilation” in unconscious patients by viewing the wind pipe while delivering oxygen and incorporating channels on the facemask is described. The facemask makes it possible to oxygenate/ventilate an unconscious patient while securing a definitive airway by endotracheal intubation. The anesthetic facemask incorporates channels through which an ‘airway-slider’ fitted with a camera is inserted inside the patient's mouth, when the patient is unconscious. The airway-slider simplifies maneuvering the endotracheal tube into the patient's windpipe thus achieving a definitive clear airway with the use of just one device as opposed to the practice of needing multiple devices for the same in current anesthetic practice.

Abstract: A neonatal resuscitation mask that achieves an effective seal with a patient's face with minimal application forces. The mask can include a cushion that forms a sealing surface with a patient's face that is made from a soft gel material. The cushion can also include a restriction ring that is capable of limiting radial expansion and collapse of the cushion, when application forces are applied.

Abstract: The present technology relates to a pad for forming a seal forming structure against a user's skin for use with a patient interface, the pad comprising, a base layer, a fibre layer comprising a plurality of fibers for contacting a patient's skin, and a connection layer for connecting the fibers to the base material, wherein the base layer and/or the fibre layer is/are adapted to act as a reservoir for substances. Furthermore, it relates to a set of pads, a kit and a patient interface.

Abstract: A nasal cannula assembly is disclosed having a face mount part, in use resting against a user's face, which includes at least one nasal prong capable of being fitted into a person's nares. The cannula assembly also includes a manifold part, in fluid communication with the face mount part, having a single horizontal side gases entry. In particular, this cannula assembly is for supplying heated, humidified gases to a patient suffering from COPD. A tie or lanyard is disclosed for use with a breathing assistance apparatus such as a nasal cannula, face or nasal mask or tracheostomy connector. The tie or lanyard transfers the weight of the conduits supplying gases to the breathing assistance apparatus from the breathing assistance apparatus and distributes it onto the neck of the patient.

Abstract: A hose having an asymmetrical cross-section but which exhibits symmetrical bending and crush resistance regardless of the direction of the bending and/or crushing forces exerted on the tube. The tube includes an outer wall and an inner strengthening rib which is coextruded with the outer wall, the inner rib fabricated from a material having a durometer which is at least equal to, or higher, i.e., equal or higher resistance to deflection and/or indentation, than the material out of which the outer wall is fabricated.

Abstract: A nasal cannula assembly is disclosed having a face mount part, in use resting against a user's face, which includes at least one nasal prong capable of being fitted into a person's nares. The cannula assembly also includes a manifold part, in fluid communication with the face mount part, having a single horizontal side gases entry. In particular, this cannula assembly is for supplying heated, humidified gases to a patient suffering from COPD. A tie or lanyard is disclosed for use with a breathing assistance apparatus such as a nasal cannula, face or nasal mask or tracheostomy connector. The tie or lanyard transfers the weight of the conduits supplying gases to the breathing assistance apparatus from the breathing assistance apparatus and distributes it onto the neck of the patient.

Abstract: Described herein are various embodiments of an oxygen concentrator system. In some embodiments, oxygen concentrator system includes one or more components that improve energy usage during operation of the oxygen concentrator system.

Abstract: A breathable gas supply apparatus has a flow generator configured to pressurize a flow of breathable gas and a humidifier base unit configured to be coupled to the flow generator. A water container is configured to be removably coupled to the humidifier base unit and includes an air inlet and an air inlet passage extending into an interior of the water container from the air inlet. The air inlet passage is configured to direct the pressurized flow of breathable gas in a direction that is substantially parallel to a base of the water container. A barrier wall is provided across an outlet end of the air inlet passage and extends downward from the air inlet passage toward the water container base. In addition, a curved wall opposes both the outlet end of the air inlet passage and the barrier wall and extends downward toward the water container base.

Abstract: A humidifier assembly for a CPAP includes a base housing with a gas inlet configured to receive respiratory gas from the CPAP unit. The base housing includes a first connecting device located at a sidewall of the base housing and configured to directly, removably connect the base housing to the CPAP unit. The base housing also includes a second connecting device configured to be coupled to an air delivery hose. The humidifier assembly further includes a liquid storage container that is removably received in the base housing. The liquid storage container includes a liquid storage space configured to store liquid and a humidifying region configured to receive the respiratory gas from the gas feed opening and receive a partial amount of the liquid stored in the liquid storage space to enrich the respiratory gas with moisture.

Abstract: A patient interface includes a mask body, an elbow, a connector and a conduit. Any one or more of the mask body, the elbow, the connector and the conduit includes a bias flow vent. The bias flow vent is configured to deform with the application of pressure but not fully collapse such that an orifice size defined by the bias flow vent can vary with the application of pressure.

Abstract: A sleep sensing system comprising a sensor to obtain real-time information about a user, a sleep state logic to determine the user's current sleep state based on the real-time information. The system further comprising a sleep stage selector to select an optimal next sleep state for the user, and a sound output system to output sounds to guide the user from the current sleep state to the optimal next sleep state.

Abstract: An endoluminal device comprises a tubular member and a reinforcement member that is separable from, or together with, a wall of the tubular member, and removable in-situ.

Abstract: An aortic cannula comprises a main body portion and a distal end portion. A lumen extends through the main body portion and the distal end portion to allow fluid communication between the main body portion and the distal end portion. The distal end portion has an inner wall and an outer wall. There is a passageway disposed between the inner wall and the outer wall of the distal end portion. The passageway has an inlet and an outlet, and the passageway is fluid communication with a surrounding environment. There may be a stop ring disposed about the distal end portion between the inlet of the passageway and outlet of the passageway.

Abstract: An elongate medical device having an axis comprises an inner liner, a jacket radially outward of the liner, a braid comprising metal embedded in the jacket, a sensor, and at least one wire electrically connected to said sensor. The at least one wire is one of: embedded in the jacket and optionally disposed helically around the braid; extending longitudinally within a tube which extends generally parallel to the device axis and wherein the tube is embedded in the jacket; and disposed within a lumen, wherein the lumen extends longitudinally within the jacket.

Abstract: A catheter with a mechanism for omni-directional deflection of a catheter shaft includes a shaft assembly and a controller. The shaft assembly includes a first tubular component that has a preformed curvilinear distal section, a second, substantially straight tubular component with a main axis and an outer shaft. The first and second components are configured for slidable movement therebetween while preserving common rotation so that when the second component is axially moved in a distal direction, the second component deflects the preformed curvilinear section towards the main axis while orientation of the outer shaft is preserved. The controller is configured to effect relative axial movement between the first and second components as well as to effect rotation of the first and second components (and thus also of the preformed curvilinear distal section) without any rotation of the shaft relative to the handle.

Abstract: The invention relates to a low profile lumen free balloon catheter and a system for advancing the lumen free balloon from a build wire to a wire guide. The low profile balloon lacks an internal wire guide cannula between the catheter shaft and the soft tip. A releasable engagement is provided to connect/disconnect the build wire to/from the wire guide. A soft tip seals around the wire guide following advancement of the balloon catheter over the wire guide.

Abstract: Provided is a catheter fixing band for fixing a tube bent and connected to a catheter to the catheter fixing band. According to the present disclosure, a catheter fixing band includes: a body detachably fixed to a human body and having a catheter hole open to expose a portion of the human body; and a cover unit detachably attached to the body to open or close the catheter hole, in which the cover unit includes a fixing member fixing the catheter to a predetermined position of the cover unit, and has a shape forming integral concept in relation to flow of fluid in the catheter when the cover unit covers the catheter hole and the catheter is fixed to the fixing member.

Abstract: A device for controlling visibility and access to central venous access devices is comprised of a two-sided body fitted around the torso of a patient. The device has an interior surface and an exterior surface. The interior surface is fitted with a layer of absorbent, wicking material and further includes strips of anti-slip material to fix the device in place. A flexible window is positioned between two lumen retaining flaps and fixed between the interior and exterior surfaces. The lumen retaining flaps create pockets to store and protect lumens attached to intravenous tubing. The body includes a flexible closure including a resilient gauze section to provide flexibility and size adjustability. The window allows visual access to the percutaneous site and prevents patient tampering.

Abstract: Intravenous access is achieved by introducing a catheter having a guidewire safety tip at its distal end. The safety tip can be advanced and retracted using a slider disposed over an access needle which is initially present in the catheter. After the catheter has been properly positioned, the access needle and guidewire may be removed so that the catheter is available for use.

Abstract: Guide wires, systems and methods can improve advancement through the vasculature, particularly when the catheter tip encounters resistance or an obstruction and cannot advance. The guide wire can include an enlargement spaced proximally from a distal tip of the elongated member alone or in combination with a configured portion of the wire. The configured guide wire can be positioned in the vasculature and a medical device such as a catheter can track over the guide wire. The catheter can get caught-up in the vasculature or on implanted devices during advancement. When that occurs, the configured guide wire can be retracted back to the catheter tip and the guide wire configuration can cause the catheter distal tip to move and/or deflect away from the obstruction or resistance allowing the system to advance. The guide wire can be returned to its distal position and the procedure can continue.

Abstract: A guidewire includes a shaft element and a flexible distal torque transmission element. The torque transmission element can be formed of a coiled wire having one or more of the loops that are welded or otherwise fixed together to achieve desirable flexibility and torque transmission.

Abstract: A medical balloon (10) is made radiographic, such as by incorporating a radiopaque foil (36) or film layer (35). The radiopaque foil or film layer may be placed between an inner layer (30) and an outer layer (32) of a non-compliant balloon wall. The foil or film may provide the balloon with a radiographic quality from a first end to a second end in the absence of an inflation fluid. The balloon may be provided with the foil or film in a manner that provides a first section, such as the barrel (16), with a first radiographic quality, and a second section, such as the cone (18, 20), with a second radiographic quality. The film may also be applied as a decal or applique to the external surface of a balloon-shaped body. Related methods are also disclosed.

Abstract: A system and method for perfusing a liquid medicament into tissue of a patient requires a catheter having a distal barrier and a proximal barrier mounted on the catheter. A perfusion section is formed into the catheter between these barriers. By way of example of a typical operation, the catheter is advanced through the vasculature of a patient and into the coronary sinus. Advancement continues until the barriers of the catheter are positioned to straddle the ostium of the left atrial vein. As so positioned, a perfusion chamber is established in the coronary sinus between the barriers. Also, the perfusion chamber is positioned for fluid communication with the left atrial vein. Liquid medicament can then be transferred from a source into the perfusion chamber for perfusion of the medicament into tissue of the atrial vein.

Abstract: A system for bypassing an anastomosis site in a hollow organ is provided. The system includes a sleeve configured for spanning the anastomosis site at an internal surface of the hollow organ and a band configured for attachment to an external surface of the hollow organ and limiting migration of the sleeve beyond the anastomosis site.

Abstract: Devices for reducing the risk of pregnancy complications, including preterm labor and preterm birth, are disclosed herein. Also disclosed are devices in combination with therapies and medicaments for the treatment of pregnancy complications. Also disclosed are methods of using the devices for the treatment of pregnancy complications.