Patents Issued in May 11, 2017
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Publication number: 20170130152Abstract: The present invention relates to a system for drying coal using reheat steam, and more particularly, to an apparatus for enhancing drying efficiency by adjusting reheat steam to be injected to coal input and transferred onto a transfer device at predetermined pressure in a multi-stage dryer drying the coal by using reheat steam and in the apparatus for adjusting steam pressure in a system for drying coal using reheat steam, a steam supply pipe supplying the reheat steam generated by a reheater is connected to one side of each of the first steam chamber, the second steam chamber, the third steam chamber, and the fourth steam chamber and a first steam distribution perforated plate with a plurality of steam injection holes is coupled to and installed in the inner upper part of each of the first steam chamber, the second steam chamber, the third steam chamber, and the fourth steam chamber to inject the reheat steam at uniform pressure through the first steam injection holes.Type: ApplicationFiled: June 17, 2015Publication date: May 11, 2017Inventor: Sung Kon KIM
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Publication number: 20170130153Abstract: The present invention relates to the use of an olefin-carboxylic acid copolymer, wherein the copolymer comprises at least one free carboxylic acid side group, or of a nitrogen compound quaternized with epoxide in the presence of an olefin-carboxylic acid copolymer, wherein the copolymer comprises at least one free carboxylic acid side group, as a fuel additive or lubricant additive; to processes for preparing additives of this kind, and to fuels and lubricants additized therewith; such as, more particularly, as a detergent additive; for reduction or prevention of deposits in the injection systems of direct injection diesel engines, especially in common rail injection systems, for reduction of the fuel consumption of direct injection diesel engines, especially of diesel engines with common rail injection systems, and for minimization of power loss in direct injection diesel engines, especially in diesel engines with common rail injection systems; and as an additive for gasoline fuels, especially for operationType: ApplicationFiled: December 4, 2014Publication date: May 11, 2017Applicant: BASF SEInventors: Maxim PERETOLCHIN, Harald BOEHNKE, Wolfgang GRABARSE, Ludwig VOELKEL, mARKUS HANSCH, Guenter OETTER, Aaron FLORES-FIGUEROA, Klaus MUEHLBACH, Ivette GARCIA CASTRO
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Publication number: 20170130154Abstract: Hydrocarbon streams, such as crude oil streams, may have reduced drag when an effective amount to reduce drag of a drag reducing composition is added to a liquid hydrocarbon, where the drag reducing composition includes a drag reducing latex comprising at least one plasticizer in an amount effective to improve the ability to pump the latex into a hydrocarbon composition or stream with assured flow of the latex. Latex formulations are known to cause agglomerated particles during pumping operations, and the agglomerated hard particles tend to plug check valves in injection pump equipment, but the inclusion of at least one plasticizer reduces or prevents such problems.Type: ApplicationFiled: January 26, 2017Publication date: May 11, 2017Applicant: BAKER HUGHES INCORPORATEDInventors: NAGESH S. KOMMAREDDI, KEITH D. FAIRCHILD, JACK B. WARD, ROSS POLAND, JERRY J. WEERS
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Publication number: 20170130155Abstract: A coating composition for forming a lubricating layer (3) on the surface of a base material (1) formed in a predetermined shape so as to exhibit improved sliding property to fluid substances, the coating composition containing, as a dispersion medium, a liquid (5) that is a component constituting the lubricating layer (3), and the dispersion medium containing solid particles (7) dispersed therein as a component constituting the lubricating layer (3). The lubricating layer (3) formed by using the coating composition exhibits more improved sliding property to fluid substances. The coating composition, therefore, can be favorably used for forming the lubricating layer (3) on the inner surfaces of the packing materials such as containers and lids.Type: ApplicationFiled: June 18, 2015Publication date: May 11, 2017Applicant: Toyo Seikan Co., Ltd.Inventors: Yoshiaki OKADA, Tomoyuki MIYAZAKI, Keisuke NYUU
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Publication number: 20170130156Abstract: A lubricant including: an ionic liquid, which includes a conjugate acid (B+) and a conjugate base (X?), and is protic, wherein the ionic liquid is represented by the following general formula (1), and wherein the conjugate base is a conjugate base of sulfonic acid, a conjugate base of sulfonimide, or a conjugate base of trisulfonylmethide: where R1 and R2 each represent a hydrogen atom or R1 and R2 form a benzene ring together with carbon atoms to which R1 and R2 are bonded, R3 represents a to straight-chain hydrocarbon group having 10 or more carbon atoms, and R4 represents a hydrogen atom or a hydrocarbon group in the general formula (1).Type: ApplicationFiled: May 18, 2015Publication date: May 11, 2017Applicant: DEXERIALS CORPORATIONInventors: Hirofumi KONDO, Kouki HATSUDA, Makiya ITO, Nobuo TANO, Kyungsung YUN, Masayoshi WATANABE
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Publication number: 20170130157Abstract: A grease composition according to an embodiment includes a base oil, a thickener and 0.5% by weight or more of a dispersing agent, the dispersing agent including at least one of a carboxylic acid metal salt, a metal salt of a polycarboxylic acid and a copolymer of a carboxylic acid metal salt and a hydrocarbon compound.Type: ApplicationFiled: November 9, 2016Publication date: May 11, 2017Applicant: MINEBEA CO., LTD.Inventors: Yusuke ASAI, Yusuke ENOMOTO, Shintaro TAKATA
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Publication number: 20170130158Abstract: A lubricating oil composition that hardly generates precipitation attributable to a molybdenum compound under the low temperature environment and is excellent in a friction-reducing effect under the low temperature environment is provided. The lubricating oil composition is one including (A) a lubricating base oil, (B) a molybdenum-based compound, (C) a metal-based detergent, and (D) an ester compound having one or more hydroxyl groups in a molecule thereof, wherein the metal-based detergent (C) includes (C1) a calcium detergent and (C2) a magnesium detergent, and a content of the ester compound (D) having one or more hydroxyl groups in a molecule thereof is 0.03 to 1.20 mass % on a basis of the total amount of the lubricating oil composition.Type: ApplicationFiled: March 30, 2016Publication date: May 11, 2017Applicant: IDEMITSU KOSAN CO., LTD.Inventor: Kazushi TAMURA
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Publication number: 20170130159Abstract: This disclosure relates to syndiotactic polymers containing units derived from propylene and units derived from C4 to C20 alpha olefins. The polymers can be prepared is slurry or solution polymerization processes using a zirconium-containing metallocene catalyst system. The polymers have a melt flow rate as determined by ASTM D-1238 (230° C., 2.16 kg) of from about 0.1 to about 20 g/10 min. The syndiotactic polymers are useful as viscosity index improvers.Type: ApplicationFiled: June 18, 2015Publication date: May 11, 2017Inventors: Anthony J. Dias, Jo Ann M. Canich, George Rodriguez, Liehpao O. Farng, Jean-Roch H. Schauder
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Publication number: 20170130160Abstract: Provided are a lubricant composition in which low friction and low abrasion are compatible in various temperatures and loads, and a manufacturing method of a lubricant composition. A lubricant composition of the present invention contains at least trivalent or more polyol a1; a mixture b1 of at least one of a polymerization reaction mixture of an unsaturated fatty acid having 18 to 22 carbon atoms which contains at least 75 mass % of a divalent carboxylic acid having 36 to 44 carbon atoms or a mixture obtained by performing hydrogenation with respect to the polymerization reaction mixture; and composite ester A containing polyester in which monool c1 represented by General Formula (1) described below is condensed, in which a feed ratio of the number of moles of a hydroxyl group of a1/the number of moles of a carboxylic acid of b1/the number of moles of a hydroxyl group of c1 is 1/1.5 to 2.0/0.7 to 1.5, and a content of the composite ester A is 0.Type: ApplicationFiled: January 24, 2017Publication date: May 11, 2017Applicant: FUJIFILM CorporationInventor: Kunihiko KODAMA
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Publication number: 20170130161Abstract: A biodegradable compressor oil comprising a biobased hydrocarbon base oil.Type: ApplicationFiled: June 12, 2015Publication date: May 11, 2017Inventors: Paula VETTEL, Hyeok HAHN, Jeffrey BROWN, Jason WELLS
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Publication number: 20170130162Abstract: An oleaginous corrosion-resistant lubricating composition comprising at least one poly-alpha olefin synthetic oil and effective amounts of metal salts of sulfonic acids metal salts of carboxylic acids, metal salts of mixtures or combinations of sulfonic and carboxylic acids, alkylated aromatic compounds as solubility modifiers, pour-point depressants, at least one antioxidant, and metal deactivator compounds.Type: ApplicationFiled: January 26, 2017Publication date: May 11, 2017Applicant: United States of America as represented by the Secretary of the NavyInventor: El Sayed Arafat
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Publication number: 20170130163Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which comprises: (a) purifying the feed mixture in a first chromatographic separation step using an eluent a mixture of water and a first organic solvent, to obtain an intermediate product; and (b) purifying the intermediate product in a second chromatographic separation step using as eluent a mixture of water and a second organic solvent, to obtain the PUFA product, wherein the second organic solvent is different from the first organic solvent and has a polarity index which differs from the polarity index of the first organic solvent by between 0.1 and 2.Type: ApplicationFiled: January 20, 2017Publication date: May 11, 2017Inventors: Adam Kelliher, Angus Morrison
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Publication number: 20170130164Abstract: The present invention relates to a composition, in particular, a fabric conditioning composition, comprising at least a quaternary ammonium compound, a cationic polysaccharide, a nonionic polysaccharide and a fragrance material or perfume. In particular, the quaternary ammonium compound is a biodegradable quaternary ammonium compound. The composition has excellent softening performance and improved perfume longevity.Type: ApplicationFiled: January 15, 2015Publication date: May 11, 2017Inventors: Hai Zhou ZHANG, Nikolay CHRISTOV, Da Wei JIN
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Publication number: 20170130165Abstract: The present invention relates to a method for enhancing fragrance or perfume longevity of a composition by adding to the composition (a) a quaternary ammonium compound; (b) a cationic polysaccharide; (c) a nonionic polysaccharide; and (d) a fragrance material or perfume. In particular, the quaternary ammonium compound is a biodegradable quaternary ammonium compound. The composition has improved perfume longevity.Type: ApplicationFiled: January 15, 2015Publication date: May 11, 2017Inventors: Hai Zhou ZHANG, Nikolay CHRISTOV, Da Wei JIN
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Publication number: 20170130166Abstract: Shaped particles having a longitudinal length (L) and a predetermined complex cross-sectional shape extending on a plane perpendicular to said longitudinal length (L). The cross-sectional shape has at least one vertex. An edge extends along the length L from the vertex. The particles further comprise an anchoring element disposed away from the edge. The ratio of said length (L) to a perimeter-equivalent diameter of said predetermined cross-sectional shape “ECD PHull” is between about 0.5 and about 5.Type: ApplicationFiled: November 6, 2015Publication date: May 11, 2017Inventors: Denis Alfred Gonzales, Michael Leslie Groombridge, Michael McDonnell
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Publication number: 20170130167Abstract: The invention meets the needs above by providing a surfactant system, mixture or blend that can be used as a part of a soaking composition. The surfactant system is capable of forming emulsions with, and thus removing, oily and greasy stains. In a preferred embodiment the surfactant compositions of the invention can remove non-trans fat and fatty acid stains. The invention involves foaming soaking compositions that have some or part of the anionic surfactant present in the same replaced with an extended chain anionic surfactant.Type: ApplicationFiled: July 6, 2016Publication date: May 11, 2017Inventors: Victor Fuk-Pong Man, Yvonne Marie Killeen, Derrick Richard Anderson
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Publication number: 20170130168Abstract: A formulation including (A) at least one compound selected from methylglycine diacetate (MGDA) and glutamic acid diacetate (GLDA) and salts thereof, (B) at least one graft copolymer composed of (a) at least one graft base selected from nonionic monosaccharides, disaccharides, oligosaccharides and polysaccharides, and side chains obtainable by grafting on of (b) at least one ethylenically unsaturated mono- or dicarboxylic acid and (c) at least one compound of the general formula (I), where the variables are defined as follows: R1 is selected from methyl and hydrogen, A1 is selected from C2-C4-alkylene, R2 are identical or different and selected from C1-C4-alkyl, X? is selected from halide, mono-C1-C4-alkyl sulfate and sulfate.Type: ApplicationFiled: June 12, 2015Publication date: May 11, 2017Inventors: Holger Türk, Heike Weber, Gazi Türkoglu
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Publication number: 20170130169Abstract: A cleaning agent is proposed that includes a first and a second protease, wherein a) the first protease comprises an amino acid sequence which is at least 80% identical to the amino acid sequence specified in SEQ ID NO. 1 over the entire length and has at least one amino acid substitution at one of the positions 9, 15, 66, 212, and 239 using the numbering according to SEQ ID NO. 1, and b) the second protease comprises an amino acid sequence which is at least 80% identical to the amino acid sequence specified in SEQ ID NO. 2 over the entire length and has at least one amino acid substitution at one of the positions 32, 33, 48-54, 58-62, 94-107, 116, 123-133, 150, 152-156, 158-161, 164, 169, 175-186, 197, 198, and 203-216 using the numbering according to SEQ ID NO. 2.Type: ApplicationFiled: June 18, 2015Publication date: May 11, 2017Applicant: Henkel AG & Co. KGaAInventors: Thomas Eiting, Nina Mussmann, Thorsten Bastigkeit, Konstantin Benda, Timothy O'Connell, Hendrik Hellmuth, Silke Menke
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Publication number: 20170130170Abstract: Dishwashing composition comprising an enzyme preparation, which enzyme preparation comprises enzymes capable of degrading cellulosic material. The enzyme preparation may comprise: a) an Aspergillus fumigatus cellobiohydrolase I; b) an Aspergillus fumigatus cellobiohydrolase II; c) an Aspergillus fumigatus beta-glucosidase or variant thereof; and d) a Penicillium sp. GH61 polypeptide having cellulolytic enhancing activity; or homologs thereof. The dishwashing composition can be used in a method for automatic dishwashing for example in combination with an acidic material or it can be used for cleaning the interior of the dishwashing machine. The addition of a non-pathogenic microorganism, e.g. Bacillus subtilis, to the dishwashing detergent is also suggested.Type: ApplicationFiled: March 25, 2015Publication date: May 11, 2017Applicant: Novozymes A/SInventor: Jan Peter Skagerlind
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Publication number: 20170130171Abstract: The present invention relates to a cleaning composition for cleaning medical instruments. The cleaning composition of the invention comprises: an enzyme activity protector complex; an enzyme system; one or more controlling polymers; surfactants; organic solvent; and additives selected from chelating agents, wetting agents, preservatives and water. In particular, the cleaning composition of the invention is a low foaming, multi enzymatic cleaner having excellent efficacy for enzymatic cleaning, hard water scale inhibition and rust inhibition due to scaling. The composition further provides shine with superior wetting and cleaning performance. The invention also relates to a process for preparing a cleaning composition and a method of cleaning medical instruments employing the cleaning composition of the present invention.Type: ApplicationFiled: June 22, 2015Publication date: May 11, 2017Inventors: RAJENDRA H. VISHNUMURTHY, VISHALKUMAR Y. JOSHI
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Publication number: 20170130172Abstract: The present application relates processes that can be used to produce encapsulated benefit agents comprising a core and a shell that encapsulates said core, encapsulated benefit agents produced by such process and products comprising such encapsulated benefit agents as well as methods of making and using such products. Such process can be used to produce particles that offer the desired protection and release benefits when used in a varity of products.Type: ApplicationFiled: January 10, 2017Publication date: May 11, 2017Inventors: Johan SMETS, Susana FERNANDEZ PRIETO, Raul RODRIGO GOMEZ, Albert GASULL MORALES, Jennifer Efua Kwansima QUANSAH
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Publication number: 20170130173Abstract: Described is a method for removing rust from a rusted surface comprising the steps of a) applying to the said surface a first composition comprising a penetrating oil, and b) applying to the said surface a second composition comprising at least one thiol compound, the thiol compound being a thiol substituted carboxylic acid, or a salt or alkyl ester thereof, wherein step b) is carried out prior to, or subsequent, to step a), a kit comprising said first and second compositions, a composition and also to the use of said composition for rust removal.Type: ApplicationFiled: June 12, 2015Publication date: May 11, 2017Inventor: Louis OTTENS
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Publication number: 20170130174Abstract: The invention provides a substrate detergent composition used for cleaning a surface of a substrate, comprising: (A) A quaternary ammonium salt: 0.1 to 2.0% by mass; (B) Water: 0.1 to 4.0% by mass; and (C) An organic solvent: 94.0 to 99.8% by mass. There can be provided a substrate detergent composition used for cleaning a surface of a substrate contaminated with a silicone component whose water contact angle is 100° or more.Type: ApplicationFiled: January 25, 2017Publication date: May 11, 2017Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventors: Masaya UENO, Hideyoshi YANAGISAWA
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Publication number: 20170130175Abstract: The present invention discloses a method for manufacturing a heavy-duty laundry detergent wipe, characterized by the following steps: (a) hydrophobic coating of a hydrophilic substrate or hydrophilic coating of a hydrophobic substrate for obtaining a multilayered carrier substrate which is solid at ambient temperature, (b) applying a dispersion consisting of a liquid washing detergent and a water insoluble functional additive to the substrate. The present invention further discloses a heavy-duty laundry detergent wipe, comprising a substrate which is solid at ambient temperature and a dispersion applied to the substrate and consisting of a liquid washing detergent and a water insoluble functional additive, characterized in that the carrier substrate consists of a hydrophilic substrate provided with a hydrophobic coating or of a hydrophobic substrate provided with a hydrophilic coating.Type: ApplicationFiled: June 11, 2015Publication date: May 11, 2017Applicant: COIN CONSULTING UG (HAFTUNGSBESCHRÄNKT)Inventors: Marcus Mausberg, Michael Pulina
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Publication number: 20170130176Abstract: The present invention discloses a method for manufacturing a laundry detergent, characterized by the following steps: (a) incorporating oxygen donors and their activators in a waxy matrix which is surrounded by an ionic polymer layer for providing a capsule system, (b) incorporating the capsule system into a liquid washing detergent. Furthermore, a liquid washing detergent is disclosed, characterized by a capsule system comprising a waxy matrix which is surrounded by an ionic polymer layer and into which oxygen donors and their activators are incorporated.Type: ApplicationFiled: June 11, 2015Publication date: May 11, 2017Applicant: COIN CONSULTING UG (HAFTUNGSBESCHRÄNKT)Inventor: Marcus Mausberg
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Publication number: 20170130177Abstract: A pulp container may contain beer making ingredients during the beer making process. The container may have a bag, filter, or other sieve that may retain the ingredients during the brewing process, and may be compostable and disposable after the brewing process has completed. The container may contain prepared ingredients that may be pre-packaged such that a user may drop the container with the prepared ingredients into a system for brewing beer. In some cases, a container may contain grains and other ingredients that may be used for a mashing step. In other cases, a container may contain one or more hops charges and may have boiling or near boiling water. The brewing system may include recirculating brewing systems, as well as other types of brewing techniques.Type: ApplicationFiled: January 26, 2017Publication date: May 11, 2017Inventor: Avi R. Geiger
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Publication number: 20170130178Abstract: A user interface for a beer recipe creator may have a series of icons that may represent ingredients. A user may drag and drop or otherwise add the icons to containers on a display screen to add or remove ingredients to the recipe. With each added or removed ingredient, a set of descriptors may be updated. The descriptors may include numerical values of beer parameters as well as textual descriptions and visual descriptions. The system may allow a user to start with a desired beer style, and the parameters may show variances from the selected style. The system may generate an ingredients list, as well as a brewing recipe that may be transferred to a controller for a beer making machine. The system may adjust certain parameters that are controllable by the beer making machine to make flavor and other adjustments selected by a user.Type: ApplicationFiled: January 26, 2017Publication date: May 11, 2017Applicant: PicoBrew, LLCInventor: William H. Mitchell
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Publication number: 20170130179Abstract: The present invention aims to provide colored foods that retain their inherent good flavors and which yet feature suppressed fading of dyes. Provided are colored foods that contain rosmarinic acid and which are reduced in the contents of luteolin-3?-glucuronide, carnosic acid, and carnosol.Type: ApplicationFiled: July 3, 2015Publication date: May 11, 2017Applicant: SUNTORY HOLDINGS LIMITEDInventors: Norihiko KAGEYAMA, Takahiro OHIRO
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Publication number: 20170130180Abstract: The present invention relates to a method of cleaning or filtering beer, having the following steps: applying beer onto an obliquely positioned filter (10), so that the beer runs down along the obliquely positioned filter (10) and liquid contained therein passes through openings of the filter (10) into a collecting space (20) beneath the filter (10) and solids contained in the beer slide downwards along the obliquely positioned filter (10), and routing the filtered beer out of the collecting space (20). The invention also relates to a beer cleaning apparatus.Type: ApplicationFiled: October 28, 2016Publication date: May 11, 2017Inventor: Wilhelm Mitter
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Publication number: 20170130181Abstract: The invention relates to a method for a photochemical process, such as a photocatalytic and/or photosynthetic process, in particular for the culture and production or the hydroculture of microorganisms. A reaction medium (6) is conducted in a meandering manner in a reactor element (2) which is made of at least two upright and connected pipes (3) or chambers (13). Multiple reactor elements (2) are serially connected into a bio solar reactor (1), and a reaction medium (6) flow which is stress-free for the microorganisms is generated in the bio solar reactor (1) using hydrostatic pressure and level compensation. Inlet and outlet openings (4, 5) are arranged on the lower face (8) of each individual reactor element (2) on each of the outermost pipes (3) or chambers (13). The reaction medium (6) flows around all of the connections in the lower region, in particular the inlet opening (4), the outlet opening (5), and the introduction inlet (17).Type: ApplicationFiled: May 27, 2015Publication date: May 11, 2017Applicant: ECODUNA AGInventor: Franz EMMINGER
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Publication number: 20170130182Abstract: The subject matter herein provides a biotic method for recovering one or more hydrocarbons from a feedstock that includes one or more of oil shale, bituminous tar sand, coal and cellulous at atmospheric temperature and pressure. The method comprises loading the feedstock into a container, treating the feedstock in the container with a biomedium of micro-organisms, and forming an essentially liquid mixture from the feedstock and the biomass by rotary tumbling the feedstock and the biomedium in the container. The essentially liquid mixture is then separated into the one or more hydrocarbons by centrifuging.Type: ApplicationFiled: January 23, 2017Publication date: May 11, 2017Inventor: Raymond ROGER WALLAGE
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Publication number: 20170130183Abstract: The present invention discloses a device for cell culturing and processing, applicable in the field of biological and genetic engineering experiments, which comprises at least one central distribution compartment, at least one incubation compartment; at least one processing compartment, a number of ducts to transfer fluids between said compartments, wherein a distribution cavity and a piston capable of moving back and forth in said distribution cavity for altering the operational volume of said distribution cavity are provided within said central distribution compartment, and a distribution valve controlling the connection between said distribution cavity and said ducts is provided at one end of said distribution cavity within the distribution compartment. During operation, cells grow and multiply in a cell suspension contained in the incubation compartment.Type: ApplicationFiled: April 11, 2014Publication date: May 11, 2017Inventors: Jinming Cui, Shijie Zeng, Olaf Eichstaedt, Jiandong Huang, Ruxu Du
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Publication number: 20170130184Abstract: The present invention relates to a hollow microfiber comprising (1) one or more cell-adhesive layers having a cell-adhesive hydrogel, (2) an outer shell layer having a high-strength hydrogel that covers the outer periphery of the cell-adhesive layer that is positioned farthest from the center axis among the one or more cell-adhesive layers, and (3) a cell layer that covers the inner periphery of the cell-adhesive layer that is positioned closest to the center axis among the one or more cell-adhesive layers. The present invention also relates to a method of manufacturing the hollow microfiber and a kit for carrying out the manufacturing method.Type: ApplicationFiled: May 20, 2015Publication date: May 11, 2017Inventors: Shoji TAKEUCHI, Hiroaki ONOE, Shigenori MIURA
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Publication number: 20170130185Abstract: A homogenized and integrated device with a coaxial line and double-high pressure cylinder, includes a long oil cylinder, two main connecting sleeves, two high pressure cylindrical homogenized main bodies, two auxiliary connecting sleeves and two short oil cylinders. The two main connecting sleeves, two high pressure cylindrical homogenized main bodies, two auxiliary connecting sleeves and two short oil cylinders are respectively and symmetrically arranged at two ends of the long oil cylinder and are assembled with the long oil cylinder along a same axial line. Each high pressure cylindrical homogenized main body is integrally connected with the long oil cylinder by virtue of one of the main connecting sleeves. Each high pressure cylindrical homogenized main body is integrally connected with the corresponding short oil cylinder by virtue of one of the auxiliary connecting sleeves.Type: ApplicationFiled: March 31, 2015Publication date: May 11, 2017Applicant: Guangzhou Juneng Nano&Bio Technology Co.,LtdInventors: XingWen YU, Qian YU
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Publication number: 20170130186Abstract: Aspect of the disclosure relate to methods of assessing a bioreactor culture that involve determining a culture parameter of the manufacturing-scale bioreactor culture using a model that relates a Raman spectrum to the culture parameter. Related bioreactor system are also provided.Type: ApplicationFiled: July 2, 2015Publication date: May 11, 2017Applicant: Biogen MA Inc.Inventors: Brandon Berry, Justin Moretto
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Publication number: 20170130187Abstract: A pressure regulator module for a chip-based microfluidic platform is provided. The module includes a microfluidic channel for passing flowable material from the inlet region through the outlet region and into a downstream compartment; one or more microvalves fluidly connected to the microfluidic channel and upstream of the outlet region; and one or more reservoirs fluidly connected to the microvalves, for receiving flowable material diverted by the microvalves, where a flow of flowable material passing from the inlet region toward the downstream compartment is at least partially diverted by the microvalves into the reservoirs as a result of a pressure increase in the microfluidic channel. In some versions, the microvalves are capillary burst valves. A microfluidic chip containing the module and a method of using the module are provided.Type: ApplicationFiled: October 24, 2016Publication date: May 11, 2017Inventors: Abraham P. Lee, Xiaolin Wang, Duc Phan, Christopher C.W. Hughes, Steven C. George
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Publication number: 20170130188Abstract: An observation apparatus is equipped with a housing including a top plate that is a stage on which a container that accommodates a sample is placed; an optical system accommodated in the housing; an imaging device configured to capture an image of the sample with light from the sample that has entered through the stage and the optical system; and a motor that is a power source of a moving mechanism configured to make the optical system move in a direction along the stage. At least one of the imaging device or the motor is placed outside the housing.Type: ApplicationFiled: October 25, 2016Publication date: May 11, 2017Applicant: OLYMPUS CORPORATIONInventors: Yoshihiro UE, Tomio ENDO, Osamu ONO, Akira MATSUSHITA, Yohei TANIKAWA
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Publication number: 20170130189Abstract: An automatic culturing device configured such that, in a work chamber 2a maintained in a sterile state, first and second robots 6 and 7 are arranged so that the movable ranges thereof partially overlap each other, and such that liquid supply means 10 which supplies liquids, containing a culture medium and liquid medicine, to containers held by the robots, and temporary placement sections (handing-over table 42, centrifuge tube holder 43, and heated room 44), each of which hands over the containers between the first and second robots, are provided in the movable ranges of the first and second robots, which ranges overlap each other. The first robot takes out the containers housed in housing means (rotary stocker 8), and the second robot holds and transports the containers handed over from the first robot via the temporary placement section. The cultivating operation can be efficiently performed.Type: ApplicationFiled: June 12, 2015Publication date: May 11, 2017Applicant: SHIBUYA CORPORATIONInventors: Masahiro SAKAMOTO, Noriaki NISHIMURA
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Publication number: 20170130190Abstract: New strains of microalgae belonging to the Nitzschia genus allow high-yield production of lipids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and/or carotenoids such as fucoxanthin. Biomass containing the microalgae can be charged with fucoxanthin representing more than 0.2% by weight of the dry matter.Type: ApplicationFiled: January 13, 2017Publication date: May 11, 2017Inventors: Khadidja ROMARI, François GODART, Pierre CALLEJA
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Publication number: 20170130191Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.Type: ApplicationFiled: June 20, 2016Publication date: May 11, 2017Inventors: Itzcoatl A. Pla, Joseph G. Matuck, John C. Fann, Christof Schulz, Nichole A. Roy, David F. Bruton, James McIntire, Yu-hsiang D. Chang, Thomas Seewoester
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Publication number: 20170130192Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.Type: ApplicationFiled: November 9, 2015Publication date: May 11, 2017Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
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Publication number: 20170130193Abstract: In a first aspect, the present application relates to a method for producing a tissue model comprising supply structures. In a further aspect, the application relates to tissue models that can he obtained in this way and to the use of said tissue models as models for tissue genesis, in particular tumorigenesis, including angiogenesis, in the tissue model. Finally, a method for testing and identifying active ingredient candidates, including treatment strategies, is provided.Type: ApplicationFiled: July 6, 2015Publication date: May 11, 2017Inventors: Andreas BLAESER, Benjamin THEEK, Twan LAMMERS, Fabian KIESSLING, Horst FISCHER
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Publication number: 20170130194Abstract: The present invention relates to graphene oxide-coated nanofiber scaffold that provides instructive physical cues to the differentiation of stem cells into selected cell lineages or networks.Type: ApplicationFiled: April 10, 2015Publication date: May 11, 2017Applicant: Rutgers, The State University of New JerseyInventors: Ki-Bum Lee, Shreyas Shah
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Publication number: 20170130195Abstract: The present invention provides a cell culture substrate comprising a polymer formed of a cyclosiloxane compound and a manufacturing method therefor, and a method for preparing a cell spheroid type of cell aggregate or induced pluripotent stem cells using the cell culture substrate. The cell spheroid type of cell aggregate can be easily formed by culturing cells on the cell culture substrate of the present invention, and further, the cell culture substrate can be utilized as a cell culture platform for preparing the induced pluripotent stem cells.Type: ApplicationFiled: August 1, 2014Publication date: May 11, 2017Inventors: Sung Gap IM, Hak Rae LEE, Sang Yong JON, Min Suk CHOI
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Publication number: 20170130196Abstract: A cell scaffold includes a string having a diameter of less than 500 ?m; a hydrogel matrix supported on the string; and cells seeded onto the hydrogel matrix. The scaffold is used to cultivate cells, and to evaluate cell viability or cell metabolic activity.Type: ApplicationFiled: November 8, 2016Publication date: May 11, 2017Inventors: Gulden CAMCI-UNAL, George M. WHITESIDES
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Publication number: 20170130197Abstract: Protein enriched micro-vesicles and methods of making and using the same are provided. Aspects of the methods include maintaining a cell having a membrane-associated protein comprising a first dimerization domain and a target protein having a second dimerization domain under conditions sufficient to produce a micro-vesicle from the cell, wherein the micro-vesicle includes the target protein. Also provided are cells, reagents and kits that find use in making the micro-vesicles, as well as methods of using the micro-vesicles, e.g., in research and therapeutic applications.Type: ApplicationFiled: January 25, 2017Publication date: May 11, 2017Inventors: Michael Haugwitz, Thomas Patrick Quinn, Andrew Alan Farmer, Montserrat Morell Fernández
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Publication number: 20170130198Abstract: Disclosed are certain heterocyclic organic compounds that inhibit mitochondrial respiration and also lead to the maintenance of pluripotency of human embryonic stem cells in culture, even in the presence of oxygen. Exemplified are compounds, such as substituted 5-aminotetrazoles, which are reversible mitochondrial inhibitors. The pluripotency of the stem cells after culture is verified by the overexpression of pluripotent stem cell markers, exemplified by at least one of the genes NANOG, OCT4, and SURVIVIN after periods of culture in ambient oxygen.Type: ApplicationFiled: June 19, 2015Publication date: May 11, 2017Inventors: David Alvin Tyvoll, Christopher S. Navara, James P. Collman, Christopher Jeffrey Barile
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Publication number: 20170130199Abstract: The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent stem cells, including human embryonic stem cells (hESC), somatic stem cells, and induced human pluripotent stem cells (hiPSC) using novel culture conditions. Specifically, methods are provided for obtaining neural tissue, floor plate cells, and placode including induction of neural plate development in hESCs for obtaining midbrain dopamine (DA) neurons, motorneurons, and sensory neurons. Further, neural plate tissue obtained using methods of the present inventions are contemplated for use in co-cultures with other tissues as inducers for shifting differentiation pathways, i.e. patterning.Type: ApplicationFiled: January 30, 2014Publication date: May 11, 2017Applicant: Memorial Sloan Kettering Cancer CenterInventors: Stuart Chambers, Lorenz Studer
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Publication number: 20170130200Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.Type: ApplicationFiled: July 29, 2016Publication date: May 11, 2017Inventors: Branden MORIARITY, Beau WEBBER, R. Scott MCIVOR, Modassir CHOUDHRY
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Publication number: 20170130201Abstract: Methods of preparing platelet-rich plasma (PRP) compositions are disclosed which include adding CD34+ cells to the PRP composition. In addition, the concentration of stromal-derived factor-1 (SDF-1) in the PRP composition may be adjusted to a pre-determined value. The compositions may have elevated levels of white blood cells but reduced levels of neutrophils. Compositions produced by the method are also disclosed.Type: ApplicationFiled: January 24, 2017Publication date: May 11, 2017Inventor: Allan Mishra