Abstract: A system and method for automatically implementing a therapy for treating sleep disordered breathing.

Abstract: A system and method for sleep disorder diagnosis and treatment are disclosed. A particular embodiment includes: establishing a wireless data communication interface between a networked server and a sleep metering system worn by a user, the sleep metering system including a sensor array, wireless transceiver, and a processor; activating the sleep metering system to begin collection of sensor data from the user based on data signals from the sensor array of the sleep metering system; receiving a respiratory waveform and data corresponding to a level of arterial oxygen saturation (SpO2) in the user's blood over time as an SpO2 waveform based on the collected sensor data; receiving a set of user-configured control variables; and generating a sleep efficiency score based on the respiratory waveform, the SpO2 waveform, and the user-configured control variables, the sleep efficiency score including a log of the user's respiratory effort reduction events (RERE) and respiratory effort exaggeration events.

Abstract: Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.

Abstract: A system and method of monitoring sobriety using a hand-held breath testing device that, on receipt of a user's breath, generates a breath test signal comprising substance content data and user identification data, and wirelessly transmits the breath test signal to a breath test signal receiving station.

Abstract: An electronic device and method are disclosed herein. The electronic device includes a sensor, and a processor. The processor may implement the method, including acquiring, by the sensor, first biometric information of a user, determining alcohol information for determining a presence of of alcohol in the user from the first biometric information, determining second biometric information of the user related to the alcohol information, and generating health information to be displayed the user or transmitted to another electronic device based on the second biometric information.

Abstract: Systems, devices, and methods for detecting, measuring and classifying meals for an individual based on analyte measurements. These results and related information can be presented to the individual to show the individual which meals are causing the most severe analyte response. These results can be organized and categorized based on preselected criteria or previous meals and results so as to organize and present the results in a format with reference to glucose as the monitored analyte. Various embodiments disclosed herein relate to methods, systems, and software applications intended to engage an individual by providing direct and timely feedback regarding the individual's meal-related glycemic response.

Abstract: A new fabrication process for flexible and wearable microfluidic channel structures and devices is provided. Microfluidic channel structures and devices can be printed on textiles and in particular on flexible fabrics, such as clothing, for applications in wearable microfluidic sensors and systems. The wearable and flexible microfluidic devices are fabricated from water-insoluable plastisol polymers, which may be screen-printable, and sheets of paper may be used as a sacrificial substrate during production.

Abstract: A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.

Abstract: This disclosure concerns a carrier system for a medical device worn on the body comprising a flexible carrier plaster which has a flat carrier layer and an adhesive coating thereon consisting of a pressure sensitive adhesive which adheres on the skin of a body part, and further comprising a platform which is positioned on the upper side of the carrier layer for mounting the device, wherein the platform has a bottom joining area which is joined to the upper side of the carrier layer by means of a structural adhesive which is applied as a bead along predefined adherend tracks.

Abstract: This disclosure concerns a medical sensor assembly comprising a flexible plaster adapted for adhesion on the skin of a patient and a sensor configured for transdermal measuring a physiological parameter, wherein the sensor has a measuring part insertable into the skin and a contact part for providing a signal connection to a measuring unit. It is proposed that the plaster has a flap which is adhered to an intermediate section of the sensor between the measuring part and the contact part.

Abstract: A balloon assembly for an anorectal manometry catheter may include a three-part tube and a balloon mountable on the tube. The three-part tube may include a flexible proximal connection tube (PCT), a flexible distal connection tube (DCT), and a semi-flexible transfer tube that is interposed between and connected to each of said PCT and said DCT. The balloon may have a first opening connected to a first end of the transfer tube and a second opening connected to a second end of the transfer tube which is opposite the first end of the transfer tube. The three-part tube may be configured to be slidable along and over a catheter in a first direction, with the DCT slid first. The three-part tube may also be configured to be slidable over the catheter in the opposite direction such that the PCT is folded onto itself and completely contained in the transfer tube.

Abstract: Transducer-based systems and methods may be configured to display a graphical representation of a transducer-based device, the graphical representation including graphical elements corresponding to transducers of the transducer-based device, and also including between graphical elements respectively associated with a set of the transducers and respectively associated with a region of space between the transducers of the transducer-based device. Selection of graphical elements and/or between graphical elements can cause activation of the set of transducers associated with the selected elements. Transducer activation characteristics, such as initiation time, activation duration, activation sequence, and energy delivery characteristics, can vary based on numerous factors. Visual characteristics of graphical elements and between graphical elements can change based on an activation-status of the corresponding transducers.

Abstract: A medical monitoring system and method for monitoring a patient is provided. A sensor is implanted within the patient. A biomarker is detected via the implanted sensor within the patient. The detected biomarker is indicative of a neural respiratory drive (NRD) of the patient. An NRD index value is generated based on the detected biomarker.

Abstract: Provided are implantable and bioresorbable medical devices comprising a bioresorbable substrate and an electronic circuit supported by the bioresorbable substrate. The electronic circuit comprises a membrane of silicon having a thickness less than or equal to 5 ?m and an array of dissolvable electrodes, wherein the dissolvable electrodes are formed from the membrane of silicon. The electronic circuit is configured to conformally contact a biological tissue and electrically interface with biological tissue during use. The silicon may be highly doped to provide the requisite characteristics for electrically interfacing with biological tissue, and may be further used to form other components of the electronic circuit, including back-plane transistors electrically connected to the electrode array.

Abstract: This application is related to a system for measuring eye pressure and related methods. In some embodiments, the system includes a pressure sensor and a processor. The pressure sensor takes a measurement from a contact with an eyelid. The processor includes an engine that is built from a set of items, each comprising a list of user attribute values, the eye pressure measured by the pressure sensor, and the actual eye pressure level, and can estimate the actual eye pressure level and normalized eye pressure level. Given a new measurement of a user's eye pressure made by the pressure sensor, the processor identifies the user attribute values for the user and runs the engine to estimate the actual eye pressure level and the normalized eye pressure level.

Abstract: Smart phones capable of detecting electrical impedances of and providing electronic pulse stimuli to acupuncture points located on a human body are disclosed. An example smart phone is equipped with a hardware diagnosis module and a hardware treatment module that function based on the principle of holography of protruding parts of the human body, in addition to having regular smart phone functions. The diagnosis module may receive electrical impedance data detected from protruding parts of a human body and determine the type of illness according to the analog electrical impedance data. The treatment module may generate electronic pulse stimuli on acupoints located on the human body (such as ears, hands and feet), thereby performing electronic acupuncture treatment. The example smart phone may also detect blood pressure, heart rate, blood oxygen value and blood glucose values of the human body.

Abstract: An object information acquiring apparatus of the present invention includes a supporter supporting a plurality of irradiators that each applies a light beam to an object and a probe that receives an acoustic wave from the object, an irradiation controller controlling the light beam from each of the plurality of irradiators, a movement controller moving position of the supporter, an acquirer acquiring information related to a light amount suppressing area, and an information processor generating characteristics information of the object, and the irradiation controller suppresses alight amount applied to the light amount suppressing area.

Abstract: Device and method for removing artifacts in physiological measurements. The method can comprise the steps of obtaining a physiological signal of a user; obtaining corresponding motion data representative of motion of the user; determining whether the physiological signal is distorted; and if the physiological signal is determined to be distorted, identifying a noise reference and filtering the physiological signal with the noise reference.

Abstract: A physiological monitoring system and method for the determination of at least one physiological parameter using a first low energy physiological sensor to produce a first physiological sensor signal and a high energy physiological sensor to produce a second physiological sensor signal. A motion sensor produces a motion reference signal that a mode selector switch uses to select either the first low energy physiological sensor or the second high energy physiological sensor. Alternatively, a motion related embedded component in the second physiological sensor signal is used by the mode selector switch to select in the first low energy sensor or the second high energy sensor.

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.

Abstract: Provided is a method and apparatus for extracting a feature of a biosignal, the method including determining an acceleration waveform from a waveform of the biosignal, extracting an incident acceleration waveform from the acceleration waveform, and extracting a feature of the biosignal based on a cross-correlation between the acceleration waveform and the incident acceleration waveform.

Abstract: An apparatus for processing a set of data values, a data value representing a physiological measure of a body fluid at a time instant, comprising: an estimated probability function calculator for calculating an estimated probability function associated with the set of data values; a transform calculator for calculating a non-linear transform rule using a predetermined target probability function being different from the estimated probability function, so that the probability function of a set of transform data values is closer to the target probability function than the estimated probability function; and a transformer for applying the transform rule to the set of data values or to at least one further data value not included in the set of data values and sampled at the different time instant from the time instants for the set of data values to obtain at least one transformed value representing the physiological measure.

Abstract: Heart rate monitor system and method of determining a warming-up status of a user A heart rate monitor system is provided which comprises an optical heart rate sensor (100) configured to measure or determine a heart rate of a user and to output an output signal (101).

Abstract: Described here are systems and methods for estimating a quantitative measure of cerebrovascular reactivity (“CVR”) from data acquired using resting-state functional magnetic resonance imaging (“fMRI”).

Abstract: An integrated imaging system for creating an optimal imaging session by importing information in real time from several sources over a network and using that information to automatically and continuously adjust the parameters of the imaging session so as to create the optimal session for the prescribed testing session.

Abstract: The invention is a system for measuring the true dimensions and orientation of objects in a two dimensional image. The system is comprised of a ruler comprising at least one set of features each comprised of two or more markers that are identifiable in the image and having a known spatial relationship between them and a software package comprising programs that allow extension of the ruler and other objects in the two dimensional image beyond their physical dimensions or shape. The system can be used together with radiographic imagery means, processing means, and display means to take x-ray images and to measure the true dimensions and orientation of objects and to aid in the identification and location of a surgery tool vs. anatomy in those x-ray images. The invention provides a method of drawing and displaying on a two dimensional x-ray image measurements of objects visible in said image, graphical information, or templates of surgical devices.

Abstract: A system for multi-mode breast imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.

Abstract: The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.

Abstract: The present disclosure relates to a system and method for digital radiography. The system may include an X-ray generation module, an X-ray acquisition module, a control module, a support module and a power supply module. The system may include one or more moving components. The X-ray acquisition module may have different configurations, such as a vertical configuration, a horizontal configuration and a free-style configuration. The control module may be configured for controlling the motion of the moving components, the selection of an X-ray acquisition module of a specific configuration, and parameters of the X-ray exposure and image acquisition. The support module may include a system of guiding rails. The power supply module may include a supercapacitor.

Abstract: A fluoroscopy system for processing and real-time display of fluoroscopy images includes a buffer storing a first image when the buffer is below a threshold as a stored image; a unit processing the stored image and generating a processed image; a display displaying processed images; and a memory storing a second image as a stored unprocessed image when the buffer is not below the threshold, and storing processed images as stored processed images.

Abstract: The invention relates to novel imaging-based biomarkers for characterizing the structure or function of a human or animal brain. These biomarkers can be a weighted confluency sum score (WCSS) or a percent shielding by brain lesions (SbBL). Methods implementing these biomarkers are also disclosed.

Abstract: An apparatus includes a plurality of detection pixels configured to generate a signal according to a radiation irradiation amount to obtain radiation irradiation information, a detection unit configured to correspond to a region of the plurality of detection pixels and detect one of light, pressure, capacitance, and temperature as two-dimensional information, and a control unit configured to determine a monitoring target detection pixel and a non-monitoring-target detection pixel among the plurality of detection pixels based on the two-dimensional information detected by the detection unit, read the signals of detection pixels of a row in which the monitoring target detection pixel is included.

Abstract: A processing device detects a medical device and sends an audio wake-up signal to the medical device, wherein the audio wake-up signal causes the medical device to transition from a low power state to a higher power state. The processing device receives a diagnostic audio signal from the medical device after sending the audio wake-up signal. The processing device processes the diagnostic audio signal to determine medical information of a patient, the medical information comprising at least one of heart beat information or breathing information of the patient. The processing device performs at least one of storing the medical information or transmitting the medical information to a remote computing device.

Abstract: An ultrasonic diagnostic device wherein: a Doppler processing unit acquires Doppler information in a living body on the basis of an ultrasonic reception signal; a velocity vector calculating unit acquires the velocity vector distribution of a blood stream in the living body on the basis of the Doppler information in the living body; and, to form a flow line showing the flow of the blood stream on the basis of the velocity vector distribution, a flow line forming unit searches for a proper start point by inversely tracing the flow of the blood stream from an initial start point along the reverse direction of the velocity vector and then forms a flow line extended from the proper start point.

Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to he studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).

Abstract: A medical image processing apparatus of an embodiment includes storage circuitry and setting-condition determining circuitry. The storage circuitry stores information about at least one of a position of a region of interest in a breast, a size of the region of interest, and a size of the breast, the information acquired based on an X-ray image of a breast of a subject. The setting-condition determining circuitry acquires a setting condition in ultrasonographic diagnosis for the breast based on the information about at least one of the position of the region of interest, the size of the region of interest, and the size of the breast.

Abstract: Ultrasound diagnostic device including: a transmitter that performs events by transmitting ultrasound focusing inside a subject by using a first transducer group that gradually shifts in an array direction between events; and a receiver that, for each event, generates receive signal sequences for transducers based on ultrasound reflection that the transducers receive in response to the event, that selects a second transducer group whose receive signals based on ultrasound reflection from a puncture needle have high intensity, that, for each event, sets a target area for generating a sub-frame data item inside a virtual area of the subject that receives ultrasound transmitted in the event, and generates the sub-frame data item by performing, for each measurement point in the target area, delay-and-sum processing on receive signal sequences for the second transducer group, and that generates a frame data item by combining sub-frame data items for events.

Abstract: An endobronchial probe includes a deflector having a bore extending therethrough at an angle to its long axis for passage of a tool. The probe includes a location sensor and an ultra-sound imager. A push-pull anchoring system comprises a plurality of guides and wires that can extend beyond the guides and retract within the guides. When extended the wires diverge from the long axis sufficiently to engage a bronchus. The probe includes a balloon disposed on the distal segment contralateral to bore that when inflated urges the mouth of the bore into contact with the bronchial wall.

Abstract: Provided are an ultrasound imaging apparatus and a method of operating the same. The ultrasound imaging apparatus may generate a plurality of color Doppler mode images by extracting a plurality of pieces of ensemble data from among ultrasound data acquired from the object.

Abstract: A LUS robotic surgical system is trainable by a surgeon to automatically move a LUS probe in a desired fashion upon command so that the surgeon does not have to do so manually during a minimally invasive surgical procedure. A sequence of 2D ultrasound image slices captured by the LUS probe according to stored instructions are processable into a 3D ultrasound computer model of an anatomic structure, which may be displayed as a 3D or 2D overlay to a camera view or in a PIP as selected by the surgeon or programmed to assist the surgeon in inspecting an anatomic structure for abnormalities. Virtual fixtures are definable so as to assist the surgeon in accurately guiding a tool to a target on the displayed ultrasound image.

Abstract: Devices and method are provided for ultrasound transmission without the need for external couplants, such as gels, which are typically used in conventional ultrasound procedures. In particular, ultrashields are provided for use with ultrasound probes, wherein the ultrashields have specialized layers to provide an uninterrupted pathway of acoustic conductance from the probe to the surface of the body throughout the procedure while introducing minimal to no attenuation of ultrasound wave transmission. In addition, combinations of ultrashields and probe covers are provided to provide additional features such as a microbial barrier.

Abstract: The present invention provides an ultrasonic endoscope in which wiring can be reliably fixed to a wire housing space of an ultrasonic-oscillator housing part, and a method of manufacturing the ultrasonic endoscope. According to the present invention, a wire housing space is encapsulated from the outside by sealing a gap formed between an ultrasonic oscillator and an ultrasonic-oscillator housing part with sealing members. With this configuration, the wire housing space can be sufficiently filled with filling agent for fixing wires in the wire housing space. This achieves an ultrasonic endoscope in which the wires can be reliably fixed to the wire housing space of the ultrasonic-oscillator housing part.

Abstract: The present invention provides an ultrasonic endoscope in which the position of an ultrasonic oscillator can be easily adjusted with respect to a surgical-tool guide opening provided to a leading end part body of an insertion unit, and a method of manufacturing the ultrasonic endoscope. According to the present invention, an ultrasonic oscillator can be positioned with respect to and temporarily fixed to an ultrasonic-oscillator housing part by using spacers and or protrusions. With this configuration, in an ultrasonic endoscope according to the present invention, the position of the ultrasonic oscillator can be adjusted with respect to the ultrasonic-oscillator housing part by using the spacers or the protrusions. Accordingly, the position of the ultrasonic oscillator can be adjusted with respect to a surgical-tool guide opening provided to a distal end part body of an insertion unit.

Abstract: A medical imaging system configured to analyze an acquired image to determine the imaging plane and orientation of the image. The medical imaging system may be further configured to determine a location of an aperture to acquire a key anatomical view and transmit instructions to a controller to move the aperture to the location. A sonographer may not need to move the ultrasound probe for the medical imaging system to move the aperture to the location. An ultrasound probe may include a transducer array that may have one or more degrees of freedom of movement within the probe. The transducer array may be translated by one or more motors that receive instructions from the controller to position the aperture.

Abstract: An ultrasound diagnosis apparatus includes: a two-dimensional (2D) transducer array in which a plurality of transducers that transmit/receive an ultrasound signal to/from an object are arranged in two dimensions; an analog beamformer configured to perform analog beamforming in a first direction, and perform analog beamforming in a second direction perpendicular to the first direction on signals respectively received by the plurality of transducers; and a digital beamformer configured to perform digital beamforming on the signals that are analog-beamformed in the first direction, and perform digital beamforming on the signals that are analog-beamformed in the second direction.

Abstract: An ultrasonic transducer device includes a base, a first electrode film, a piezoelectric film, a second electrode film and a first conductive film. The base has a plurality of vibrating film portions arranged in an array pattern. The first electrode film is disposed on each of the vibrating film portions. The piezoelectric film is disposed on the first electrode film. The second electrode film is disposed on the piezoelectric film. The first conductive film is connected to the first electrode film. The first conductive film has a film thickness larger than a film thickness of the first electrode film.

Abstract: Disclosed are an ultrasound diagnostic apparatus and an ultrasound image producing method capable of producing a spatial compound image with reduced artifacts. Reception data of frame images is repeatedly acquired in a data acquisition cycle of four frames such that, of three frame images for use in producing a spatial compound image, the angle difference in steering angle between two frames for which the acquisition of reception data is most temporally separated is smaller than a maximum value among the angle differences in steering angle between two frame images among three frame images having different steering angles, and each time reception data of two frame images or reception data of another two frame images is acquired, three frame images sequentially produced based on reception data for three frames sequentially acquired hitherto are synthesized to produce a spatial compound image.

Abstract: Disclosed are an ultrasound diagnostic apparatus and an ultrasound image producing method capable of producing a spatial compound image with reduced artifacts. Reception data of frame images is repeatedly acquired in a data acquisition cycle of four frames such that, of three frame images for use in producing a spatial compound image, the angle difference in steering angle between two frames for which the acquisition of reception data is most temporally separated is smaller than a maximum value among the angle differences in steering angle between two frame images among three frame images having different steering angles, and each time reception data of two frame images or reception data of another two frame images is acquired, three frame images sequentially produced based on reception data for three frames sequentially acquired hitherto are synthesized to produce a spatial compound image.

Abstract: Provided are an ultrasound imaging apparatus and method of generating an ultrasound image. The ultrasound imaging apparatus includes: a memory configured to store instructions; and at least one processor configured to execute the stored instructions to: generate, based on echo signals reflected from an object, a first image showing a tissue of the object and a second image showing a contrast medium injected into the object; generate a third image by removing at least a portion of the tissue from the second image based on the first image; and display the generated third image.

Abstract: A liquid sample collection device is provided. The liquid sample collection device comprises a housing including a liquid collection chamber, and a liquid supply conduit extending from an inlet port and in use generally downwardly to the collection chamber, wherein the collection chamber includes an air vent port located such that in use liquid supplied to the collection chamber through the liquid supply conduit displaces air through the air vent port, and wherein the liquid supply conduit follows a meandering path including at least one air trap section defined at the junction between portions of the conduit extending with upward and downward components respectively, whereby in use once the air vent port is closed, air is displaced along the liquid supply conduit until it is trapped by the air trap section thereby preventing further liquid flow through the conduit.