Abstract: An MRI apparatus includes an imaging data acquiring unit and a blood flow information generating unit. The imaging data acquiring unit acquires imaging data from an imaging region including myocardium, without using a contrast medium, by applying a spatial selective excitation pulse to a region including at least a part of an ascending aorta for distinguishably displaying inflowing blood flowing into the imaging region. The blood flow information generating unit generates blood flow image data based on the imaging data.

Abstract: A device for adjusting and determining the blood flow plateau at a patient's limb, wherein the device includes an chamber the wall of which surrounds an inner space, and at least one opening for inserting at least a part of the limb into the inner space as well as at least one recess, that allows access to the part of the limb that is located inside the inner space, are formed in the chamber, and wherein the device includes at least one heating element that is in thermal contact with the inner space. In this context, it is provided that the device further includes an apparatus for determining the blood flow plateau at the part of the limb that is located inside the inner space.

Abstract: Provided are a measurement apparatus, a measurement method, and an electronic device provided with a measurement apparatus that can improve the measurement accuracy of biological information. A measurement apparatus includes a measurement unit that measures biological information and a controller that performs control to suspend measurement by the measurement unit when starting predetermined processing during measurement by the measurement unit.

Abstract: A measurement apparatus includes a light source that emits a measuring beam, a light receiver that receives scattered light of the measuring beam from a test site, a biological information generator that generates biological information based on output of the light receiver, and a controller. The controller permits emission of the measuring beam from the light source during a predetermined time slot.

Abstract: A fluid control device (10) includes a container (13), a pump (11), a solenoid valve (12), and a capacitor. The pump (11) is driven by a main power source, and is capable of pressurizing or depressurizing the inside of the container (13). A suction port and a discharge port of the pump (11) internally communicate with each other. The solenoid valve (12) is connected at both ends thereof to the container (13) and the pump (11). If the voltage of the main power source is reduced or lost, the solenoid valve (12) releases pressure in the container (13) by being driven by the power stored in the capacitor or secondary battery.

Abstract: Systems and methods are provided for determining performance capacity. One such system includes a wearable device having a biosensor that measures biometrics and a motion sensor that monitors activity. The system also includes a processor coupled to the biosensor and the motion sensor, and a non-transitory computer-readable medium operatively coupled to the processor and storing instructions that, when executed, cause the processor to execute specific functions. The instructions are executed to cause the processor to generate biometric data from the biometrics and activity data from the activity. Further, the instructions are executed to create a response profile based on one or more of a heart rate variability (HRV) score based on the biometric data, a fatigue score based on the activity data, a predicted HRV score based on the biometric and activity data, and a predicted fatigue score based on the biometric data and/or the activity data.

Abstract: Photoplethysmographic device for measuring a heart rhythm, comprising a housing having a contacting surface and a control unit, a photoplethysmographic sensor mechanically attached to the contacting surface and connected to the control unit, wherein the control unit is arranged to receive a photoplethysmographic signal from the photoplethysmographic sensor, a fastening band having a first end and a second end, the first end and second end attached to the device for attaching the device to a subject with the contacting surface contacting the subject's skin, a pressure sensor attached to the contacting surface in close proximity to the photoplethysmographic sensor. The control unit is arranged determining whether the pressure from the pressure sensor is in a range suitable for photoplethysmographic measurement by the photoplethysmographic sensor.

Abstract: An animal vital signs detection system is provided which comprises at least one photoplethysmography (PPG) sensor (100) having at least one light source (110), at least one photo sensor (120) and at least one light guide unit (130) which is adapted to guide light from the light source (110) through hairs, fur or pelt to a skin of an animal (100) and light from the skin through hair, fur or pelt of the animal (1000) to the at least one photo sensor (120). By providing the light guide coupled to the light source (110) and the photo sensor (120), the PPG sensor (100) can be placed even on hair, fur or pelt of an animal (1000) while still being able to effectively direct light to the skin and detect light from the skin of an animal (1000). The ratio between a length and a diameter of the light guides is >4.

Abstract: A method of estimating a heart rate includes: measuring, using a processor, movement information based on a physical activity of a user; and estimating, using the processor, a heart rate of the user by applying the movement information to a preset regression model, wherein the regression model is based on a correlation between heart rates and movement information.

Abstract: Examples of 3D-printed sensing devices for detecting vascular conditions in an animal body are described. A 3D-printed sensing device may comprise a binding layer to attach the 3D-printed sensing device to a part of the animal body. A sensor layer is extruded atop the binding layer. The sensor layer comprises a piezoresistive transducer to generate an electrical signal based on a pulse detected in the part of the animal body. In an example, the electrical signal is a binary signal having a logical high value at an instant of occurrence of the pulse and is agnostic of a strength of the pulse. An amplification module in the sensor layer may amplify the electrical signal and provide the amplified signal to a transmitter unit of the 3D-printed sensing device to transmit the amplified signal to a monitoring device associated with the 3D-printed sensing device.

Abstract: According to the present invention, various biological signals can be measured at an appropriate position without depending on an expert. A biological-signal measurement device includes a sensor 1 that is in contact with a nerve fiber N and detects a nerve action potential generated in the nerve fiber N, a signal processor 2 that is connected to the sensor 1 via wiring 5, the signal processor 2 obtaining a signal based on the nerve action potential from the sensor 1 and wirelessly transmitting the obtained signal, and a receiving/transmitting unit 3 that receives the signal from the signal processor 2. The sensor 1 and the signal processor 2 are embedded in a body. The receiving/transmitting unit 3 receives the signal from the signal processor 2 via skin S.

Abstract: An electrocardiograph device and methods of navigating displays of such a device are disclosed. In one example, an electrocardiograph device includes a display, a plurality of electrocardiograph signal leads, and a programmable circuit. The programmable circuit is configured to receive electrical signals via the electrocardiograph signal leads representative of a heartbeat of a patient. The programmable circuit is configured to generate a user interface to be presented on the display, the user interface comprising a lead display including a screen layout including a plurality of waveform regions. The waveform regions display a waveform corresponding to an electrical signal from one of the leads over a time interval including at least one heartbeat period. Selection of a region causes display of an extended waveform region displaying a waveform over a second time interval that is longer than the first time interval, and which includes a plurality of heartbeat periods.

Abstract: A system for classifying cardiac rhythms is disclosed. The system includes one or more processors, one or more computer-readable tangible storage devices, and program instructions stored on at least one of the one or more storage devices for execution by at least one of the one or more processors. The program instructions include first program instructions to obtain data representative of a time series of the times between heartbeats. The program instructions further comprise second program instructions to segment the time series into a plurality of segments. The program instructions further comprise third program instructions to calculate a plurality of parameters corresponding to each of the 30-second segments. The program instructions further comprise fourth program instructions to analyze the obtained data and the calculated parameters using a plurality of multivariable algorithms for rhythm classification.

Abstract: An example of a system may include a sensing circuit to sense a cardiac signal indicative of atrial and ventricular depolarizations and an atrial fibrillation (AF) detection circuit to detect AF. The AF detection circuit may include a detector and a detection enhancer. The detector may be configured to detect the ventricular depolarizations using the cardiac signal, measure ventricular intervals, and detect AF using the ventricular intervals. The detection enhancer may be configured to generate atrial detection windows each being a time interval prior to each of the detected ventricular depolarizations, compute an atrial activity score using a rolling average of portions of the cardiac signal within the atrial detection windows, and verify the detection of the AF using the atrial activity score and an atrial activity threshold. The atrial activity score is a measure of consistency between a relationship between the atrial depolarizations and the ventricular depolarizations.

Abstract: An electrode device has a conductive body, a silver layer situated above the conductive body, a silver compound layer situated above the silver layer, a liquid absorbing and releasing element situated above the silver compound layer, a shielding element configured to cover an upper surface and a portion of a side surface of the liquid absorbing and releasing element, and a moving mechanism configured to move the shielding element reciprocally between at least two positions.

Abstract: The present disclosure pertains to a system and method for determining and displaying a sleep restoration level of a subject for a target sleep session. In some embodiments, the system comprises one or more of a sensor, a processor, electronic storage, a user interface, and/or other components. As the subject sleeps, the system is configured to determine a metric indicating sleep need for the subject and then graphically display a sleep restoration level (a visual representation of the metric indicating sleep need) based on the determined sleep need metric. Instead of assuming common parameters for multiple users, the system is configured to determine the sleep need metric based on obtained baseline sleep parameters that have been determined individually for the subject based on one or more previous sleep sessions, a determined amount of slow wave activity in the subject during the target sleep session, and/or other information.

Abstract: The electrode equipment of the present disclosure includes a first electrode, a second electrode having a different electrical polarity from the first electrode, and a sensor for detecting a vertical direction. The electrical polarities of the first electrode and the second electrode are determined based on output of the sensor.

Abstract: The present invention provides a medical electrode, which comprises an annular adhesive pad (203) to be attached to a living being, a conductive pad (205) disposed in the central hole (207) of the annular adhesive pad, a first conductive snap element (209), a conductive element (211) and a sealing film (213). The conductive element (211) is configured to establish electrical communication between the conductive pad (205) and the first conductive snap element (209) and the sealing film (213) is attached to the annular adhesive pad (203) and to fix at least a portion of the conductive element (211) between the annular adhesive pad (203) and the sealing film (213). The flexibility and/or length of the conductive element is chosen to be large enough so as to allow the first conductive snap element (209) to move without causing the conductive pad (205) to move, resulting in reliable electrical contact between the conductive pad and the skin of the living being.

Abstract: Apparatus for the assessment of electrophysiological signals obtained from a patient, the apparatus comprising: a housing; a support arch pivotally mounted to the housing, the support arch comprising a plurality of facial contact point supports for supporting contact points on the face of the patient relative to the support arch without supporting the chin of the patient; at least one display screen for presenting a stimulus to a single eye of the patient, the at least one display screen being movable relative to the support arch; and control electronics disposed within the housing for driving the at least one display screen and for amplifying electrophysiological signals obtained from the patient.

Abstract: Method and related system for measuring physiological parameters of a human subject undergoing an olfactory stimulation comprising one or more smelling olfactory stimuli, where by means of said system and according to said method a human subject is undergone to said olfactory stimulation by sending said one or more smelling olfactory stimuli to the human subject; one or more physiological parameters of the human subject are recorded; and said olfactory stimulation and physiological parameters recording are synchronized.

Abstract: According to one embodiment, frames of section image data including a heart are acquired from an object by magnetic resonance imaging (MRI). Spatial positional information of a reference section of the heart is calculated based on the frames of section image data. A reference section image of the heart is displayed and positioning of an imaging part for diagnostic imaging is set using the displayed reference section image of the heart. Diagnostic imaging as defined by the set positioning information is then performed.

Abstract: An mucosal impedance (“MI”) device may include or utilize a retaining member sized to retain a tines structure including N tines, each provided with one or more impedance electrodes on each tine. The retaining member may mechanically deform the tines such that they fit inside it. The tines, made of spring like material, may be chosen, for example, for their elastic modulus and yield strength. The tines may be pre-conditioned with a shape that provides a spring tension force in the radial outward direction. When the retaining member or is retracted to release and expose the tines and impedance electrodes, the preconditioned shape and elasticity of the tines cause the tines to expand radially outward, providing an appropriate contact force of the impedance electrodes on the inner wall of the esophagus for a range of esophageal diameters.

Abstract: In a flexible catheterization probe a resilient member couples the tip to the distal portion of the probe and is configured to deform in response to pressure exerted on the tip when engaging tissue. A position sensor in the distal portion of the probe senses the position of the tip relative to the distal portion of the probe. The relative position changes in response to deformation of the resilient member. The position sensor generates a signal indicative of the position of the tip responsively to a magnetic field produced by a magnetic field generator located in the position sensor. The position sensor has a first coil of conductive wire having first windings, and three second coils of conductive wire having respective second windings. The second coils are symmetrically distributed about the longitudinal axis of the first coil.

Abstract: Provided herein are injectable biophotonic sensors and systems thereof. Also provided herein are methods of and devices for delivering the injectable biophotonic sensors to a subject. Also provided herein are methods of using the injectable biophotonic sensors and systems described herein.

Abstract: The present invention provides a method for identifying biomarkers and generating an output indicative of disease. The method for identifying biomarkers comprises the steps of collecting a breath sample from subjects known to have a disease and subjects known to be free of the disease; analyzing the collected breath samples to determine all mass ions in each of the collected breath samples using at least one time-resolved separation technique and at least one mass-resolved separation technique; identifying a subset of the determined mass ions in a processor as the biomarkers for detecting the disease, the subset of the determined mass ions are statistically significant for detecting the disease; and combining the subset of the determined mass ions in a multivariate algorithm in the processor to generate a value of a discriminant function indicating the likelihood that the subject has the disease.

Abstract: A method for non-invasively monitoring a status of a user with a pulmonary condition comprises obtaining first video data of the user during a first test period; analyzing the obtained first video data to determine a first respiratory signal for the user; detecting any cough events present in the first respiratory signal; obtaining second video data of the user during a second, later, test period; analyzing the obtained second video data to determine a second respiratory signal for the user; detecting any cough events present in the second respiratory signal; determining a respiratory status of the user based on the results of the detecting and outputting a signal containing information about the respiratory status of the user.

Abstract: Devices and methods for determining various occurrences and anomalies within a step are provided. A device to determine characteristics of a step includes at least one sensor to measure acceleration of a foot in at least two directions, at least one processor to execute instructions stored in a memory and to determine accelerations in first and/or second directions meet criteria to determine a footstrike and a push off of a foot from a surface. Slipping of feet while walking and running, clipping of feet while walking and running, and tripping and falling while walking and running may be indicators of overall health and fitness, particularly in older individuals.

Abstract: A sensor system detects hand-to-mouth behavior. The system includes an electrical bio-impedance spectrometer and an inertial measurement unit. The sensor system may be worn on the forearm. The sensor system recognizes hand-to-mouth behavior in real-time, facilitating monitoring and immediate interventions An electrode positioning strategy optimizes the device's sensitivity and accuracy. Machine learning algorithms are leveraged to infer the hand-to-mouth detection. A prototype of the sensor system achieves 92% detection accuracy for recurrent usage by a single user and 90% accuracy for users that have not been previously encountered.

Abstract: In an implementation of the disclosed subject matter, a device may emit a first emission sequence of infrared radiation at a subject, and capture a first reflected sequence of infrared radiation reflected from the subject. The first emission sequence may be compared to the first reflected sequence, and, based on the comparison, a sequence of variations may be determined. The sequence of variations may be compared to signal pattern stored in a sleep profile for the subject. The subject may be determined to have exhibited sleep behavior based on the comparison of the sequence of variations to the signal pattern stored in the sleep profile. In response to determining the subject has exhibited sleep behavior, the device may capture a second reflected sequence of radiation reflected from the subject. A breathing rate of the subject and/or a heart rate of the subject may be determined based on the second reflected sequence.

Abstract: A hemoglobin detection apparatus comprises a spectrally tuneable emitter-detector unit, which is configured to emit or detect electromagnetic radiation spectrally selectively and periodically at different wavelengths covering a spectral modulation interval at a modulation frequency, and to provide a detector signal indicative of the detected electromagnetic radiation as a function of time. The apparatus further comprises a signal processing unit, which is configured to receive the detector signal and to provide an output signal, which is indicative of a contribution of at least one frequency component that forms a second or higher even harmonic of the modulation frequency to the detector signal. The hemoglobin detection apparatus can be used in photoplethysmography applications.

Abstract: A sensor set is provided for sensing of a body characteristic, such as glucose. The sensor set includes a mounting base for the sensor and a connector to connect to the mounting base and has an improved structure for connecting the mounting base to the connector. The connector may contain sensor electronics for wired or wireless communication to an external monitor or display. The mounting base includes latch arms and the connector adapted to fit and lock into latch recesses on the connector and includes anti-rotation arms adapted to fit into anti-rotation arm recesses on the connector.

Abstract: Systems and methods of the present invention provide a calibration model that requires minimal information compared with prior techniques. These systems and methods represent the first generalized approach for combined treatment of spectroscopic measurements of a dynamic, mass-transfer system with the underlying kinetic model of said system. The technique can be applied to non-invasive glucose monitoring or monitoring of chemical reaction dynamics.

Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

Abstract: An improved sensor set is provided for sensing of a body characteristic, such as glucose. The sensor set includes a mounting base for the sensor and a connector to connect to the mounting base. The connector may contain sensor electronics for wired or wireless communication to an external monitor or display. The mounting base includes a connector fitting adapted to fit into a tubular recess in the connector, wherein the connector fitting includes a key. In some embodiments, the proximal end of the sensor folds around the key such that there are contact pads on both sides of the key. The mounting base and connector include additional features, such as pegs and prongs that allow for unique fitting of compatible mounting bases and connectors, while locking out non-compatible components.

Abstract: An analytical system for examining a body fluid and a method of operation of an analytical system, typically for blood sugar tests, including an exchangeable magazine (18) as a consumable, which includes a plurality of magazine units (24) that are each provided with at least one analytical aid (32, 34) and with a transport element (28), a hand-held device (12) having a magazine guide (16) for receiving the magazine (18), a transport mechanism (48) that engages on the transport elements so as to transport the magazine in steps in the magazine guide, including a positioning mechanism (50) for positioning an active magazine unit in a predefined functional position, wherein retaining means (52, 54) of the positioning mechanism can be brought into engagement with transport elements of the magazine.

Abstract: Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.

Abstract: A device for non-contact measurement of blood oxygen saturation (SpO2) in a mammalian subject including a camera and one or more arrays of LEDs each having a first set of LEDs emitting near infrared (NIR), and the second set of LEDs emitting orange light located in an optical path adapted to transmit reflected light from a subject to the camera. A controller transmits a camera trigger to the camera, and is further coupled to transmit control signals to the one or more arrays of LEDs. A processor receives photoplethysmography (PPG) data signal values from the camera. The PPG data signal values are present in the reflected light and include pulsatile and non-pulsatile components. The processor determines SpO2 values from the PPG data signal values from the measured ratios of pulsatile to non-pulsatile components of the PPG signals.

Abstract: Methods and devices to detect analyte in body fluid are provided. Embodiments include analyte sensors designed so that at least a portion of the sensor is positionable beneath a skin surface in the dermal layer.

Abstract: The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Abstract: The present invention generally relates to systems and methods for receiving blood (or other bodily fluids) from a subject, e.g., from or beneath the skin of a subject. In some cases, the blood (or other bodily fluids) may be deposited on a membrane or other substrate. For example, blood may be absorbed in a substrate, and dried in some cases to produce a dried blood spot. In one aspect, the present invention is generally directed to devices and methods for receiving blood from a subject, e.g., from the skin, using devices including a substance transfer component (which may contain, for example, one or more microneedles), and directing the blood on a substrate, e.g., for absorbing blood. The substrate, in some embodiments, may comprise filter paper or cotton-based paper. After absorption of some blood onto the substrate, the substrate may be removed from the device and shipped or analyzed. In some cases, the device itself may be shipped or analyzed.

Abstract: A fatigue-degree monitoring device includes a first-fatigue-indicator calculating section configured to calculate a first indicator concerning fatigue of a user on the basis of operation from an operation section, a second-fatigue-indicator calculating section configured to calculate a second indicator concerning the fatigue of the user on the basis of biological information of the user, and a fatigue determining section configured to determine a fatigue degree of the user on the basis of the first indicator and the second indicator.

Abstract: A data acquisition device includes measuring instruments to generate physiological and/or psychological data streams. Microprocessors within the acquisition device process the generated data streams into metrics, which feed into stress function algorithms. Algorithm processing may occur either on the device, or metrics may be communicated via wireless communication for external processing on mobile devices and/or cloud-based platforms. The calculated stress functions inform cloud-based computational systems biology-derived models describing the dynamics of hormones and neurotransmitters released in the body in response to stressful stimuli. Stress hormone levels are quantified using these models, and are used in combination to serve as biologically inspired metrics of acute and chronic stress an individual is experiencing.

Abstract: Method and system for monitoring the autonomic nervous system (ANS) of a subject, comprising acquiring at least one physiological signal having W heartbeats, generating data which is a function of the variability of the heart rate on the W heartbeats, with the HRV having W?1 RR intervals separating two consecutive heartbeats detected respectively at the moments tk?1 and tk, each RR interval having a duration of value a?=t??t??1 with k=(X?W+2) . . . X; calculating at least one parameter taken from the parameter TAS(tx) representing the level of activity of the sympathetic system and/or the parameter TAP(tx) representing the level of activity of the parasympathetic system; and/or other parameters such as the parameter SL(tx) representing stress level of the subject at the moment tx and calculated using the equation such that SL(tx)=100+TAS(tx)?TAP(tx); and supplying data representative of at least one parameter.

Abstract: Embodiments disclosed herein are directed to devices, systems, and methods for monitoring pregnancy of a female pregnant subject. For example, a pregnancy monitoring system can detect movement or motion of a pregnant subject and/or of the fetus in the pregnant subject. Additionally or alternatively, the pregnancy monitoring system can detect internal and/or external source loads applied to the pregnant subject. In an embodiment, the pregnancy monitoring system can compare and/or correlate two or more loads, one to another (e.g., to produce an output that is at least partially based on such comparison and that is related to the wellbeing of the pregnant subject and/or of the fetus). For example, the pregnancy monitoring system can include a controller that is configured to determine and compare two or more loads based on signals received from one or more sensors that can be positioned on the pregnant subject.

Abstract: Embodiments disclosed herein are directed to devices, systems, and methods for monitoring pregnancy of a female pregnant subject. For example, a pregnancy monitoring system can detect movement or motion of a pregnant subject and/or of the fetus in the pregnant subject. Additionally or alternatively, the pregnancy monitoring system can detect internal and/or external source loads applied to the pregnant subject. In an embodiment, the pregnancy monitoring system can compare and/or correlate two or more loads, one to another (e.g., to produce an output that is in part based on such comparison and that is related to the wellbeing of the pregnant subject and/or of the fetus). For example, the pregnancy monitoring system can include a controller that is configured to determine and compare two or more loads based on signals received from one or more sensors that can be positioned on the pregnant subject.

Abstract: Embodiments disclosed herein are directed to devices, systems, and methods for monitoring pregnancy of a female pregnant subject. For example, a pregnancy monitoring system can detect movement or motion of a pregnant subject and/or of the fetus in the pregnant subject. Additionally or alternatively, the pregnancy monitoring system can detect internal and/or external source loads applied to the pregnant subject. In an embodiment, the pregnancy monitoring system can compare and/or correlate two or more loads, one to another (e.g., to produce an output that is in part based on such comparison and that is related to the wellbeing of the pregnant subject and/or of the fetus). For example, the pregnancy monitoring system can include a controller that is configured to determine and compare two or more loads based on signals received from one or more sensors that can be positioned on the pregnant subject.

Abstract: The present invention relates to a wrinkle measurement apparatus and a wrinkle measurement method. The wrinkle measurement apparatus according to one embodiment of the present invention comprises: a surface direction compression part including first and second contact parts arranged at a preset gap while coming into close contact with the skin, so as to compress the skin in the direction of the surface thereof; and a wrinkle measuring part for measuring skin wrinkles in at least two states among pre-compression, mid-compression and post-compression.

Abstract: A footwear system having a plurality of temperature sensors determines the emergence of an ulcer or pre-ulcer on a person's foot. After the plurality of temperature sensors generate a plurality of discrete temperature data values, the system and method form a temperature map representing substantially the actual geometric shape of at least a portion of the foot, and the distribution of temperatures of the at least a portion of the foot. Next, the method and system determine whether the temperature map presents at least one of a plurality of prescribed patterns, and produces output information indicating an emergence of an ulcer or a pre-ulcer on a given portion on the foot. The output information is produced as a function of whether the temperature map is determined to present the at least one of the plurality of prescribed patterns.

Abstract: A method and apparatus for monitoring a living animal is disclosed. The apparatus includes a flexible carrier strip having an undersurface for adhering to an epidermis of the living animal. The apparatus also includes a muscle function sensor disposed on the flexible carrier strip and operable to generate a muscle signal indicative of functioning of a muscle underlying the flexible carrier strip. The apparatus further includes a transducer disposed on the flexible carrier strip operable to generate a stimulus signal in response to receiving mechanical stimuli, a processor circuit disposed on the flexible carrier strip.

Abstract: Disclosed herein are methods and devices for monitoring a subject at rest. One such device comprises a sensing unit having a fluid-filled bladder configured to be placed under a substrate on which the subject lays and a sensor in fluid communication with the bladder. The sensor is configured to sense pressure variations within the bladder generated by a heart beat, respiration and body weight of the subject and to generate signals indicative of the pressure variations. A processor is configured to receive the signals and to determine and generate output indicative of the subject's heart beat and respiration and presence on the substrate. An external device is configured to display one or more of the output.