Patents Issued in May 18, 2017
  • TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING
    Publication number: 20170135926
    Abstract: Embodiments of the invention are generally directed to compositions useful for reducing pigmentation in the skin. The composition may further include other depigmenting agents such as nicotinamide and its melanasome transfer-inhibiting derivatives, 3,3?-thiodipropanoic acid and its tyrosinase-inhibiting derivatives, or resorcinol and its tyrosinase-inhibiting derivatives, in a topically acceptable vehicle.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Hong Hu, Sunghan Yim, Uma Santhanam, John W. Lyga
  • HAIR CONDITIONING COMPOSITION COMPRISING CYCLIC COMPOUNDS AND COMPOUNDS HAVING AT LEAST THREE HEAD GROUPS
    Publication number: 20170135927
    Abstract: Disclosed is a hair conditioning composition comprising: a cationic surfactant; a high melting point fatty compound; a cyclic compound selected from the group consisting of a vitamin B3 compound, a xanthine compound, a salicylic acid ester, and mixtures thereof; a compound having at least three large head groups; and an aqueous carrier. The composition of the present invention provides improved hair manageability.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Inventor: Muisiang Soh
  • COMPOSITION SUITABLE TO PRESERVE THE PHYSIOLOGICAL CONDITION OF SKIN AND HAIR AND REESTABLISH THEIR REGENERATIVE FUNCTIONS
    Publication number: 20170135928
    Abstract: The present invention relates to a composition for pharmaceutical, nutritional or cosmetic use, suitable to preserve the physiological condition and health of skin and hair and to reestablish their regenerative functions, characterized in that it comprises a mixture of carnitine, caffeine and arginine as active principle, as such or as derivatives, such as pharmacologically acceptable salts. The effect of preserving the physiologic condition and health of skin and hair, and of reestablishing their regenerative functions is mainly achieved through an increase in ATP production by skin and hair cells.
    Type: Application
    Filed: June 25, 2015
    Publication date: May 18, 2017
    Inventors: Giammaria GIULIANI, Anna BENEDUSI, Barbara MARZANI, Antonio MASCOLO, Antonio LIMITONE
  • HAIR CONDITIONING COMPOSITION PROVIDING REDUCED SLIMY FEEL WHILE PROVIDING CONDITIONING TO WET HAIR
    Publication number: 20170135929
    Abstract: Disclosed is a hair conditioning composition having a Max force peak value of at least about 58, and a Viscosity change value of at least about 800. The composition of the present invention provides reduced slimy feel on wet hair while providing conditioning to wet hair.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Inventors: Muisiang Soh, Nobuaki Uehara, Deepa Bagchi
  • Cosmetic, dermatic, protective compositions comprising phospholipids, lecithins with peptides and at least one acetylating compound.
    Publication number: 20170135930
    Abstract: The invention refers to novel dermatic and cosmetic compositions to protect against impaired pigmentation of the skin. Locally caring Ginkgoloides are selected out of pure, high quality products comprising phospholipids and lecithins to antagonize alkyl-acyl GPC. The Ginkgoloides are bound to one or more transport proteins, carrier proteins, peptides, amino acids and these carriers contain at least one acetyl group and/or Acetyl CoA. The entire transdermal compositions then endocrinologically equilibrate the skin and the skin cells whereby acetylating compounds locally act as sun screening agent.
    Type: Application
    Filed: July 24, 2014
    Publication date: May 18, 2017
    Inventor: Ruth-Maria Korth
  • A Composition Comprising Isosorbide Monooleate
    Publication number: 20170135931
    Abstract: The present invention relates to a composition comprising isosorbide monooleate, a first surfactant selected from the group consisting of an alkyl glycoside having a weight average of the number of C-atoms in the alkyl chain of more than 11, cocoamidopropyl betaine and mixtures thereof, a second surfactant which is an alkyl glycoside having a weight average of the number of C-atoms in the alkyl chain of less than 11 and water. Furthermore it relates to a process for making this composition and to a cosmetic formulation, comprising this composition.
    Type: Application
    Filed: July 1, 2015
    Publication date: May 18, 2017
    Inventors: Claudia Stoer, Claus Nieendick, Markus Weissenegger, Daniela Prinz, Mirella Winzek, Jennifer Schoss, Markus Dierker, Norbert Boyxen, Ute Griesbach, Werner Seipel, Werner Mauer
  • METHOD OF IMPROVING HAIR QUALITY BY IMPROVING SCALP HEALTH
    Publication number: 20170135932
    Abstract: A method of improving the health of hair emerging from a scalp comprising application of a composition to reduce oxidative stress in the scalp causing reduced oxidative stress in pre-emergent hair resulting in healthier emergent hair having reduced water absorption and reduced surface energy
    Type: Application
    Filed: May 26, 2016
    Publication date: May 18, 2017
    Inventors: James Robert Schwartz, James Patrick Henry, Michael Joseph Flagler, Steven Hardy Page, Kathleen Marie Kerr, Kenneth Robert Wehmeyer, Lijuan Li, Nancy Lee Redman-Furey
  • PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS
    Publication number: 20170135933
    Abstract: UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one dibenzoylmethane compound, (b) at least one 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) at least one siliceous s-triazine compound substituted with two aminobenzoate or aminobenzamide groups, or a tautomeric form thereof, the 1,3,5-triazine compounds being improvedly photostable in such compositions.
    Type: Application
    Filed: August 16, 2016
    Publication date: May 18, 2017
    Applicant: L'OREAL
    Inventor: Didier CANDAU
  • Mouth Rinse for Prevention of Periodontal Disease
    Publication number: 20170135934
    Abstract: The present invention causes the tissues in the gingiva to be less permeable to the products of bacterial metabolism produced from dental plaque. In addition, chemicals derived from the ingestion of foods and beverages are blocked from entry into the gingival tissues. This results in the prevention of oral infections and, most importantly, the loss of teeth. In addition to the ingress of toxic chemicals, this mouth rinse results in cessation of gingival crevicular fluid, a medium for bacteria to thrive on. The overall result is a healthy periodontium which is free of infected tissues and inflammation and bodes well for optimum oral and systemic health.
    Type: Application
    Filed: November 18, 2015
    Publication date: May 18, 2017
    Inventor: Henry Mallek
  • Dentifrice Compositions With Improved Consumer Experience
    Publication number: 20170135935
    Abstract: A dentifrice composition containing water, a calcium-containing abrasive, a fluoride ion source, and a thickening system providing a consumer preferred experience.
    Type: Application
    Filed: November 10, 2016
    Publication date: May 18, 2017
    Inventors: Swapna Basa, Ross Strand
  • Dentifrice Compositions With Anti-Tartar And Anti-Bacterial Benefit
    Publication number: 20170135936
    Abstract: A dentifrice composition containing water, a calcium-containing abrasive, a fluoride ion source, a zinc ion source, and a copolymer of maleic anhydride and methyl vinyl ether.
    Type: Application
    Filed: November 10, 2016
    Publication date: May 18, 2017
    Inventors: Thanigaivel Shanmugam, Ross Strand
  • Mascara Composition And Method
    Publication number: 20170135937
    Abstract: Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided. Methods of preparing the cationically-charged particulates are also disclosed.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 18, 2017
    Inventor: Wilson A. Lee
  • Mascara Composition And Method
    Publication number: 20170135938
    Abstract: Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided. Methods of preparing the cationically-charged particulates are also disclosed.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 18, 2017
    Inventor: Wilson A. Lee
  • Mascara Composition And Method
    Publication number: 20170135939
    Abstract: Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided. Methods of preparing the cationically-charged particulates are also disclosed.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 18, 2017
    Inventor: Wilson A. Lee
  • Mascara Composition And Method
    Publication number: 20170135940
    Abstract: Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided. Methods of preparing the cationically-charged particulates are also disclosed.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 18, 2017
    Inventor: Wilson A. Lee
  • POLYMERIC NITRONES AND THEIR USE IN PERSONAL CARE
    Publication number: 20170135941
    Abstract: Provided are polymeric nitrones comprising polymerized units of (a) acrylates of Formula I: wherein R1 and R2 are as defined herein; and (b) nitrone-pendant esters of Formula II: wherein R3 and R4 are as defined herein, and Z is a nitrone substituent of Formula III: wherein R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are as defined herein, and wherein the sum of m+n is a number from 10 to 50, and the ratio of m to n is from 1:1 to 20:1.
    Type: Application
    Filed: June 25, 2015
    Publication date: May 18, 2017
    Inventors: George D. Green, Raymond J. Swedo
  • Compositions for Keratin Fibers
    Publication number: 20170135942
    Abstract: The present invention relates generally to compositions and methods of using them to treat keratin fibers. More particularly, the compositions according to the invention, such as mascaras and other cosmetics, comprise polyamide gelling agents and soft waxes, and are useful for imparting the appearance of enhanced length and volume to the treated keratin fibers.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 18, 2017
    Inventors: Candice DeLeo Novack, Kelly Hales
  • GEL-LIKE HAIR-SETTING AGENT
    Publication number: 20170135943
    Abstract: The present invention relates to a silicon dioxide-containing cosmetic composition for hair setting or for the temporary reshaping of keratinic fibers, in particular human hair, which depending on the use enables both a matte and a shiny look and which after application to the hair enables shaping and restructuring of the hairstyle for a long period of time and furthermore forms no visible residues.
    Type: Application
    Filed: November 8, 2016
    Publication date: May 18, 2017
    Applicant: Henkel AG & Co. KGaA
    Inventors: Anna Puls, Marcus Noll
  • HAIR CONDITIONING COMPOSITION PROVIDING IMPROVED HAIR MANAGEABILITY
    Publication number: 20170135944
    Abstract: Disclosed is a hair conditioning composition comprising from about 0.1% to about 20% by weight of a silicone compound, and wherein the composition has a Silicone deposition amount of at least about 1,600, and Silicone deposition evenness value of at least 0.83. The composition of the present invention provides improved hair manageability.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Inventors: Muisiang Soh, Nobuaki Uehara
  • COMPOSITIONS FOR KERATIN-CONTAINING FIBERS, COMPRISING AT LEAST ONE SPECIFIC UNCROSSLINKED ANIONIC POLYMER AND AT LEAST ONE FURTHER SPECIFIC UNCROSSLINKED CATIONIC POLYMER
    Publication number: 20170135945
    Abstract: Cosmetic compositions for temporarily deforming keratinic fibers, cosmetic products, and methods for temporarily deforming keratinic fibers are provided herein. In one embodiment, a cosmetic composition for temporarily deforming keratinic fibers includes at least one uncrosslinked anionic polymer, at least one uncrosslinked cationic polymer, and water in a total amount of from about 80 to about 98% by weight, in relation to the total weight of the cosmetic composition.
    Type: Application
    Filed: May 13, 2015
    Publication date: May 18, 2017
    Applicant: Henkel AG & Co. KGaA
    Inventors: Thorsten Knappe, Marie Meisel
  • Moldable Composition for Keratin Fibers
    Publication number: 20170135946
    Abstract: The present invention relates generally to compositions and methods of using them to treat keratin fibers. More particularly, the compositions according to the invention, such as mascaras and other cosmetics, comprise gelling agents and soft waxes, and are useful for imparting moldability to treated keratin fibers.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 18, 2017
    Inventors: Candice DeLeo Novack, Alicia N. Potuck
  • Hair-Applicable Composition to Visually Identify a Single Child amongst Other Children in a Public Setting
    Publication number: 20170135947
    Abstract: A hair-applicable composition and method for visually identifying a single child amongst other children engaging in water-related activities or in another public setting. The composition includes a hair-application base and a waterproof hair dye. The hair-application base is the medium by which the waterproof hair dye is applied to the hair of a child. The waterproof hair dye includes a visually-vibrant pigmenting agent and a hydrophobic enabling agent. The visually-vibrant pigmenting agent alters the hair color of the child in order to allow a supervisor to easily identify him or her. The hydrophobic enabling agent ensures the color does not wash out with water when the child is engaging in water-related activities. The waterproof hair dye is homogeneously mixed into the topical base to create a latherable homogeneous composition.
    Type: Application
    Filed: November 16, 2015
    Publication date: May 18, 2017
    Inventor: Regina Picciano
  • COMPOSITION COMPRISING EXTRACT OF AUTUMN SOYBEAN LEAVES
    Publication number: 20170135948
    Abstract: The present specification relates to a composition for a skin preparation for external use, containing an extract of bean leaves (danpung bean leaves) of a specific stage among the growth stages of beans as an active ingredient. The composition according to the present invention has an excellent antioxidant property, an excellent antiaging property and no skin irritation since natural-derived ingredients are contained in the composition, and thus is useful. The composition of the present specification can be widely used, by such characteristics, as an antioxidant or antiaging composition of an individual in the pharmaceutical or cosmetic field.
    Type: Application
    Filed: June 18, 2015
    Publication date: May 18, 2017
    Inventors: Young Gyu KANG, Ok Chan LEE, Yong Deog HONG, Myeong Hun YEOM, Jun Seong PARK
  • COMPOSITIONS CONTAINING NATURAL EXTRACTS AND USE THEREOF FOR SKIN AND HAIR
    Publication number: 20170135949
    Abstract: The present disclosure relates to compositions containing a natural extract(s) and their fraction(s) and the use of such compositions for treatment of skin, hair and nail. For example, the present disclosure relates to compositions containing an aqueous extract of (i) Yacon leave, (ii) Amor Seco leave, or (iii) Porphyridium biomass, or a combination thereof and a pharmaceutically or cosmetically acceptable carrier use on hair skin and nails for cosmetic purposes.
    Type: Application
    Filed: November 3, 2016
    Publication date: May 18, 2017
    Inventor: Miri Seiberg
  • COSMETIC METHODS AND PRODUCTS
    Publication number: 20170135950
    Abstract: This invention relates to methods of improving the appearance of skin or hair. In particular, it relates to cosmetic products such as creams and serums comprising a subject's own platelet rich plasma (PRP). The invention also relates to kits that allow the user to apply the cosmetic products daily for several days.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 18, 2017
    Inventor: Mitra NAJAFI
  • Stable Therapeutic Formulations
    Publication number: 20170135951
    Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
  • Thermogelling Composition
    Publication number: 20170135952
    Abstract: The invention relates to a thermogelling composition comprising a chitosan having N-acetyl-glucosamine units, glucosamine units, and substituted glucosamine units other than the N-acetyl-glucosamine units, said substituted chitosan preferably having a degree of substitution of the glucosamine units ranging from 10 to 50%, expressed as a number of moles of the substituent based on the number of moles of total units, to its preparation and to its applications.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Mickaël Chausson, Renaud Lecler
  • METHODS FOR LOCALIZED DRUG DELIVERY
    Publication number: 20170135953
    Abstract: Devices, systems, and methods for localized drug delivery. In at least one embodiment of a method of localized drug delivery, the method comprises the steps of placing a resorbable device within a tube, introducing the tube within a mammalian body at or near a tissue and/or organ within the mammalian body, and anchoring the resorbable device to the tissue and/or organ. Devices and systems useful for performing such a method are also disclosed herein, wherein an exemplary device comprises at least one drug release portion having at least one drug to be released over time and a binder intermixed with the at least one drug, and at least one resorbable anchor portion coupled to the at least one drug release portion.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Ghassan S. Kassab, Jose A. Navia, SR.
  • SELF-ASSEMBLED RESIDENCE DEVICES AND RELATED METHODS
    Publication number: 20170135954
    Abstract: Residence devices as well as their related methods of manufacture and use are generally provided. In some embodiments, a residence device includes a plurality of self-assembling structures that assemble in vivo to form an aggregate structure. Each structure of the plurality of structures includes a first side and a first attachment point that attaches to a second attachment point on another structure of the plurality of structures. The aggregate structure may be sized and shaped to maintain an in vivo position relative to an internal orifice of a subject. The attachment between the first and second attachment points may degrade after a period of time.
    Type: Application
    Filed: June 11, 2015
    Publication date: May 18, 2017
    Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Jiaqi Lin, Angela DiCiccio, Dean Liang Glettig, Lowell L. Wood, JR., Philip A. Eckhoff
  • SURFACTANT-STRIPPED MICELLE COMPOSITIONS WITH HIGH CARGO TO SURFACTANT RATIO
    Publication number: 20170135955
    Abstract: Provided are compositions and methods relating to hydrophobic agent loaded-micelle. The micelles comprise surfactant (such as poloxamer) and have hydrophobic agents incorporated therein. The compositions substantially lack surfactant that is not associated with the micelles. The compositions are able to achieve high hydrophobic agent:surfactant molar ratio. The compositions can be used for drug delivery and imaging applications.
    Type: Application
    Filed: July 2, 2015
    Publication date: May 18, 2017
    Inventors: Jonathan LOVELL, Yumiao ZHANG, Wentao SONG, Jumin GENG, Chulhong KIM, Mansik JEON
  • FISH FEED COMPOSITIONS CONTAINING A NEONICOTINOID FOR PREVENTING AND TREATING PARASITE INFECTIONS
    Publication number: 20170135956
    Abstract: The present disclosure relates to methods of preventing or treating parasite infection in a plurality of fish in need thereof, comprising administering to the fish an effective amount of a medicated fish feed. The medicated fish feed comprises fish feed granules or pellets coated with a composition comprising a neonicotinoid such as imidacloprid and a carrier having a high apparent digestibility coefficient such as a processed/cooked corn protein concentrate.
    Type: Application
    Filed: June 24, 2015
    Publication date: May 18, 2017
    Inventors: John O'HALLORAN, John Terence DROST
  • CORTICOSTEROIDS FOR THE TREATMENT OF JOINT PAIN
    Publication number: 20170135957
    Abstract: Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing, arresting or reversing structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or peri-articular tissues caused by osteoarthritis or rheumatoid arthritis. Corticosteroid microparticle formulations are administered locally as a sustained release dosage form (with or without an immediate release component) that results in efficacy accompanied by clinically insignificant or no measurable effect on endogenous cortisol production.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Neil Bodick, Robert C. Blanks, Anjali Kumar, Michael D. Clayman, Mark Moran
  • Use of Vitelline Protein B as a Microencapsulating Additive
    Publication number: 20170135958
    Abstract: The present invention includes compositions and methods for the use of an encapsulation additive having between about 0.1 to about 30 percent isolated and purified vitelline protein B to provide for mixed and extended release formulations.
    Type: Application
    Filed: January 26, 2017
    Publication date: May 18, 2017
    Inventors: Allison R. Ficht, Kenneth Carson, Cynthia Sheffield, John Herbert Waite
  • TAMPER RESISTANT DOSAGE FORM COMPRISING CO-EXTRUDED, ADVERSE AGENT PARTICLES AND PROCESS OF MAKING SAME
    Publication number: 20170135959
    Abstract: The present invention relates to co-extruded pharmaceutical compositions and dosage forms comprising an adverse agent, such as an opioid antagonist, which can be sequestered. The pharmaceutical compositions and dosage forms diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods of treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient. The present invention further relates to a process for the preparation of such pharmaceutical compositions and dosage forms comprising co-extrusion of a core comprising an adverse agent and a sheath.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: Benjamin Oshlack, Hua-Pin Huang
  • AGGREGATING MICROPARTICLES FOR MEDICAL THERAPY
    Publication number: 20170135960
    Abstract: The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy. In one embodiment, the particles are used for ocular therapy. Processes for producing the surface treated microparticle and injectable formulations which include the surface treated microparticle are also provided. When used in the eye, long-term consistent intraocular delivery can be achieved without disrupting vision and minimizing undesirable inflammatory responses.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Applicant: GRAYBUG VISION, INC.
    Inventors: Yun Yu, Joshua Kays, Ming Yang, Jeffrey L. Cleland
  • PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETED NANOPARTICLES FOR THERAPY OF PROSTATE CANCER
    Publication number: 20170135961
    Abstract: The invention provides a nanoparticle composition that is decorated with a urea-based small-molecule peptidomimetic inhibitor of prostate specific membrane antigen (PSMA), which is expressed by almost all solid tumors. This strategy takes advantage of both the avidity of the functionalized nanoparticle for binding to PSMA and the ability of the nanoparticle to be retained for longer periods of time in the tumor due to enhanced leakage via EPR into the tumor interstitium and poor clearance due to underdeveloped or non-existent lymphatics within the tumor.
    Type: Application
    Filed: July 13, 2016
    Publication date: May 18, 2017
    Inventors: Sachin S. Chandran, Sangeeta Ray, Martin G. Pomper, Samuel R. Denmeade, Ronnie C. Mease
  • NOVEL DIESTER AND TRIESTER BASED LOW MOLECULAR WEIGHT, BIODEGRADEABLE CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY
    Publication number: 20170135962
    Abstract: The instant invention provides for novel cationic lipids of Formula A that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that demonstrates enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver. The present invention employs low molecular weight cationic lipids with one short lipid chain coupled with inclusion of hydrolysable functionality in the lipid chains to enhance the efficiency and tolerability of in vivo delivery of siRNA.
    Type: Application
    Filed: June 30, 2016
    Publication date: May 18, 2017
    Applicant: SIRNA THERAPEUTICS, INC.
    Inventors: Steven L. COLLETTI, Matthew G. STANTON
  • BIOACTIVE OIL BASED POLYESTERAMIDE NANOFIBERS FOR WOUND HEALING APPLICATIONS
    Publication number: 20170135963
    Abstract: Biocompatible and biodegradable nanofibers are provided. The biocompatible and biodegradable nanofibers include an oil based polyesteramide, a protein/polysaccharide, and a pharmaceutical drug useful for wound healing and biomedical applications thereof.
    Type: Application
    Filed: April 13, 2015
    Publication date: May 18, 2017
    Inventor: Rathna Venkata Naga GUNDLOORI
  • METHODS OF TREATING DISEASES ASSOCIATED WITH HIGH-FAT DIET AND VITAMIN A DEFICIENCY USING RETINOIC ACID RECEPTOR AGONISTS
    Publication number: 20170135964
    Abstract: This invention relates to pharmaceutical composition and methods of using vitamin A and/or RAR? agonist for the treatment or prevention of diseases or conditions associated with high fat diet and/or vitamin deficiency.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 18, 2017
    Inventors: LORRAINE J GUDAS, Yannick Benoit, Ronald Perez, Xiao-Han Tang, Steven Trasino
  • IMMEDIATE RELEASE ORAL GUAIFENESIN SOLUTION
    Publication number: 20170135965
    Abstract: Disclosed is an immediate release solution for oral administration of guaifenesin and at least one additional drug. In addition to water the solution comprises as solvents propylene glycol and glycerol in a concentration which significantly increases the bioavailability of guaifenesin in the human body.
    Type: Application
    Filed: January 9, 2017
    Publication date: May 18, 2017
    Inventor: Paul HAFEY
  • FEED SUPPLEMENT AND ITS USE
    Publication number: 20170135966
    Abstract: The present invention relates to feed supplements comprising vitamins and canthaxanthin and the use of such supplements for improving performance and health in poultry, in particular in poultry pullets. It has been found surprisingly that feed additive compositions as hereinafter defined improves immune status, bone and skeletal development, flock uniformity, growth and feed conversion of pullets. The feed additive composition according to the present invention comprises canthaxanthin, at least one vitamin selected from the group consisting of vitamin C and vitamin E, a trace mineral, in particular selenium, and optionally a mixture of at least two compounds selected from the group consisting of thymol, eugenol, vanillin and ?-terpinene.
    Type: Application
    Filed: January 27, 2017
    Publication date: May 18, 2017
    Inventors: Catherine HAMELIN, Rual LOPEZ ULIBARRI, Wolfgang SCHLIFFKA
  • FORMULATIONS COMPRISING 2-AMINO-2-[2-(4-OCTYLPHENYL)ETHYL]PROPANE-1,3-DIOL
    Publication number: 20170135967
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) a SI P receptor modulator; (b) a filler, and (c) a cyclodextrin.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventor: Supriya Rane
  • Methods for Storing Cysteamine Formulations and Related Methods of Treatment
    Publication number: 20170135968
    Abstract: Methods of storing and methods of stabilizing pharmaceutical compositions comprising cysteamine, or a pharmaceutically acceptable salt thereof, are provided. Methods of distributing pharmaceutical compositions comprising cysteamine, or a pharmaceutically acceptable salt thereof, and methods of treating cystinosis also are provided.
    Type: Application
    Filed: August 16, 2016
    Publication date: May 18, 2017
    Inventor: Michael DesJardin
  • TOPICAL ARGININE-SILICATE-INOSITOL FOR WOUND HEALING
    Publication number: 20170135969
    Abstract: The present invention generally relates to compositions and methods for topical or transdermal delivery, for promoting wound healing, reducing scarring, and/or promoting hair growth. Specifically, the present disclosure is directed to a topical arginine silicate formulation that demonstrates surprising improvement in wound healing time leading to more advantageous recovery and reducing hospital costs. Such formulations may also lessen scarring. The formulations may, for example, be applied to skin or to mucous membranes to facilitate wound healing.
    Type: Application
    Filed: November 10, 2016
    Publication date: May 18, 2017
    Inventor: James R. Komorowski
  • N-ACETYLCYSTEINE AMIDE (NAC AMIDE) IN THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
    Publication number: 20170135970
    Abstract: Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
    Type: Application
    Filed: October 21, 2016
    Publication date: May 18, 2017
    Inventor: Glenn A. Goldstein
  • Compositions and Methods for Treating Cancer
    Publication number: 20170135971
    Abstract: The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
    Type: Application
    Filed: November 15, 2016
    Publication date: May 18, 2017
    Inventor: HAROLD J. WANEBO
  • METHODS OF INHIBITING CATARACTS AND PRESBYOPIA
    Publication number: 20170135972
    Abstract: Described herein are methods of inhibiting or reversing the progression of cataract formation or presbyopia in an eye by administering a bifunctional molecule comprising a substituted or unsubstituted amine, succinimide, carboxylic acid, isocyanate, isothiocyanate, sulfonyl chloride, aldehyde, carbodiimide, acyl azide, anhydride, fluorobenzene, carbonate, N-hydroxysuccinimide ester, imidoester, epoxide or fluorophenyl ester covalently linked to a molecular bristle. Both presbyopia and cataracts are caused by aggregation of the soluble crystalline lens proteins called the crystallins.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Inventor: Murugappan Muthukumar
  • FORMULATIONS OF L-ORNITHINE PHENYLACETATE
    Publication number: 20170135973
    Abstract: Some embodiments of the present application are directed to oral formulations of L-ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, hepatic encephalopathy, or patients with urea cycle disorders.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Inventors: Laurene Wang, Stan Bukofzer, Linda S. Grais
  • COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE
    Publication number: 20170135974
    Abstract: Compositions comprising docosahexaenoic acid (DHA) and optionally one or more fatty acids selected from the group consisting of eicosapentaenoic acid (EPA), arachidonic acid (ARA), linoleic acid (LA), and ?-linoleic acid (ALA) are administered to felines for preventing or treating feline inflammatory bowel disease (IBD).
    Type: Application
    Filed: July 6, 2016
    Publication date: May 18, 2017
    Applicant: Hill's Pet Nutrition, Inc.
    Inventors: Christina Khoo, William David Schoenherr, Kathy Lynn Gross
  • METHOD FOR TREATING NEUROTRAUMA
    Publication number: 20170135975
    Abstract: The invention relates to a composition comprising: i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof, in which the lipid fraction comprises less than 2 weight % of ?-linolenic acid (ALA), calculated on the weight of all fatty acids; iii) choline, or salts or esters thereof; for use in the prevention or treatment of neurotrauma, traumatic brain injury, cerebral palsy and spinal cord injury.
    Type: Application
    Filed: January 27, 2017
    Publication date: May 18, 2017
    Applicant: N.V. Nutricia
    Inventors: Mattheus Cornelis DE WILDE, Johannes Wilhelmus Christina SIJBEN, Patrick Joseph Gerardus Hendrikus KAMPHUIS, Robert Johan Joseph HAGEMAN