Abstract: An infusion management system includes an infusion management server configured for providing an order to an infusion device to administer an infusion and the infusion device. The infusion device may be configured for receiving the order, associating the order with a patient, and adjusting at least one setting according to the order. A method for administering an infusion, an interface for an infusion device and a computer program product are also disclosed.

Abstract: A modular medical pump system provides separate pump units that may be pre-associated with flexible tubes. Multiple pump units may be installed in a controller that coordinates operation of the pump units for delivery of multiple medicaments to a patient. The pump units may carry drug information and the controller may hold patient information allowing drug delivery and interaction to be assessed by the controller.

Abstract: A wearable infusion pump assembly includes a reusable housing assembly, and a disposable housing assembly including a reservoir for receiving an infusible fluid. A releasable engagement assembly is configured to allow the reusable housing assembly to releasably engage the disposable housing assembly. A detachable external infusion set is configured to deliver the infusible fluid to a user.

Abstract: A Huber needle assembly. The Huber needle assembly includes a housing, a Huber needle having a bent tip, a base through which the Huber needle is slidably disposed, a tip block mechanism, and a safety or restraint mechanism. The tip block mechanism includes a needle block slidably disposed within the base and urged by a spring to block the tip of the Huber needle when the tip of the Huber needle is retracted into the base. In one exemplary embodiment, the safety or restraint mechanism includes a cable having a first end anchored within the housing and a second end anchored within the base. The cable restrains movement of the housing relative to the base. In another exemplary embodiment, the safety or restraint mechanism includes a collar disposed within the base. The collar is configured to prevent passage of the bent tip of the Huber needle.

Abstract: A tough biocompatible hydrogel having one or more drug delivery components, deformable conductors, and/or rigid electronic components incorporated therein in such a way that robust interfaces are formed between the hydrogel and the various components. The resulting hydrogel device provides a highly deformable hydrogel composite in which the reliability and functionality of the incorporated components are maintained even under states of large deformation, and from which one or more drugs can be delivered in a controlled and sustained manner regardless of the state of deformation.

Abstract: The present invention relates to an assembly for a drug delivery device comprising a dispensing container and a reservoir container for holding a fluid medicinal product, wherein the dispensing container and the reservoir container are connected to one another and are in fluid communication, and wherein the dispensing container is squeezable for dispensing a dose of the fluid medicinal product from the dispensing container, the dispensing container being refillable with the fluid medicinal product from the reservoir container.

Abstract: The present disclosure is directed to a spring arrangement for use in a drug delivery device and a drug delivery device including such a spring arrangement. The spring arrangement includes a clutch spring which is located axially interposed between a stationary housing component and an axially movable sleeve. The sleeve includes clutch features adapted to engage corresponding clutch features of a clutch element. The clutch spring biases the clutch features and the corresponding clutch features into engagement. The sleeve is coupled to a button such that upon actuation of the button the sleeve is translated against the bias of the clutch spring from a proximal position in which the sleeve is rotationally locked to the housing component into a distal position in which the sleeve is rotationally un-locked from the housing component. Upon release of the button the clutch spring translates the sleeve and the button into the proximal position.

Abstract: The invention relates to medicament delivery device (1) comprising an activating mechanism, wherein the activating mechanism comprises:—a hollow injection needle (5),—a cartridge (2) containing a dosage of a medicament,—a cartridge carrier (6) comprising at least one resilient arm (6.1) for holding the cartridge (2),—a removable needle cap (7) for covering the injection needle (5), and—a drive element (8) adapted to couple with the cartridge (2),—wherein the cartridge (2) is retained in a position spaced apart from the injection needle (5) in a proximal direction (P) by the at least one resilient arm (6.

Abstract: An injector includes a trigger mechanism including: a trigger member disposed about an axis having an aperture and a protrusion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to engage the aperture of the trigger member when the trigger member is in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a user-operable firing-initiation member having an aperture engaged with the protrusion of the trigger member and operable for causing an axial translation of the trigger member in a proximal direction from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

Abstract: A smart injection system that promotes patient safety includes, among other things, a smart stem that allows for measuring the location of the injection relative to the patient's face and/or the amount of medication injected into the patient. In addition, the smart stem has medication cartridge verification and injector verification features. The smart stem wirelessly transmits the measure data to a processing system.

Abstract: The present invention is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10) and a clutch mechanism arranged between the number sleeve (60) and the drive sleeve (40).

Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

Abstract: The present invention is generally directed to an injection device for setting and dispensing a number of user variable doses of a medicament and a method of assembling same. The injection device comprises a housing (10) having a longitudinal axis (I), a dose setting member (60; 80) rotatable relative to the housing (10) during dose setting, and a torsion spring (90) which is strained during dose setting and which is attached with its first end to the housing (10) and with its second end (91) to the dose setting member (60; 80). The dose setting member (60; 80) comprises a guide or (groove (68) with side walls having the form of a ring segment for receiving the second end (91) of the spring (90) and a non-return feature (69a, 69c) for anchoring the second end (91) of the spring (90) within the guide or groove (68) and/or an end feature (69b, 69d) located within the guide or groove (68) such that it pushes the second end (91) of the spring into contact with a side wall of the guide or groove (68).

Abstract: An autoinjector comprises a housing, a product container, a displaceable needle protection sleeve, a plunger rod displaceable by a preloaded discharge spring, a dose setting element with at least two different rotational positions relative to the housing, and a dosing sleeve. The dosing sleeve or the plunger rod has a dose selection stop, and the other has at least one dosing stop. By rotating the dose setting element, the dosing sleeve or the plunger rod is rotated relative to the other. Upon displacement of the needle protection sleeve, the spring displaces the plunger rod, whereby, if the dose setting element is in the first rotational position, the dose selection stop and the first dosing stop strikes against each other, and, if the dose setting element is in the second rotational position, one of the dose selection stop and the first dosing stop is or can be moved past the other.

Abstract: The invention is directed to a differential gear mechanism (26) for a drug delivery device with a primary drug delivery assembly (3) and a secondary drug delivery assembly (4), wherein the primary drug delivery assembly (3) comprises a primary dose dial sleeve (17) and wherein the secondary drug delivery assembly (4) comprises a secondary drive sleeve (24). The invention is also directed to a respective drug delivery device.

Abstract: The present invention relates to an injection needle assembly having opposite distal and proximal ends, and wherein the assembly comprises an injection needle having proximal and distal pointed ends, wherein the distal pointed end is arranged to penetrate a membrane arranged at the proximal end of a medicament container; a tubular needle holder comprising distal engagement means and proximal engagement means; a tubular cap comprising proximal outer engagement means and proximal inner engagement means; a tubular needle cover comprising first engagement means arranged to cooperate with the proximal engagement means, and second engagement means arranged to cooperate with the proximal outer engagement means of the cap; characterized in that said needle cover is arranged to be displaced from a first position wherein the second engagement means and the proximal outer engagement means prevents the needle cover and the needle holder to be axially displaced by a linear displacement, to a second position wherein the ne

Abstract: An injection device for expelling a dose of drug from a held cartridge (600) is described. A needle shield (350, 380) is axially movable relative to a base (200, 220, 230) between a proximal collapsed position and a distal extended position. A needle shield lock comprises a deflectable lock element (392) operable to prevent the needle shield (350, 380) from being moved towards the proximal collapsed position. A lock activator (402) associated with a plunger (310, 400) exerts an activation force on the deflectable lock element when the plunger assumes a final position. A biasing means (403) is arranged to act between the lock activator (402) and the deflectable lock element (392), the biasing means (403) being configured to resiliency transfer the activation force from the lock activator (402) to the deflectable lock element (392) to enable the needle shield (350, 380) to become locked in the distal extended position but only when the plunger (310, 400) assumes the final position.

Abstract: Provided are systems, methods, and electronic vapor devices that integrate advanced monitoring, communication, and functionality within electronic vapor devices.

Abstract: Provided are systems, methods, and electronic vapor devices configured to integrate advanced aromatic creation and distribution functionality via electronic vapor devices.

Abstract: This invention relates to a surgical smoke evacuation system for use in removing gases and smoke created in surgical procedures form within an insufflated surgical cavity.

Abstract: A dose unit comprising at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.

Abstract: A device for sealing a tracheostoma in a patient, comprising a seal member for insertion through the tracheostoma to the trachea, which in a first configuration can form a seal by being pulled against the tracheostoma, and which in a second configuration can be removed from the trachea through the tracheostoma. Preferably, the seal member comprises a disc having a predetermined line of weakness, and a first thread attached to the disc, wherein the disc can be broken along the predetermined line of weakness by pulling the thread. There is also disclosed a kit comprising the device and an external cover, a method of constructing the device, and a method of sealing a tracheostoma in a patient, comprising inserting the sealing member through the tracheostoma into the patient's trachea, and pulling the sealing member to form a seal against the tracheostoma.

Abstract: A system and method for updating patient devices is disclosed. The patient devices (720, 730, 740) may include respiratory therapy devices (4000) that operate in accordance with instruction sets (726), such as software or firmware. A server (710) may maintain a database of configuration data (718) indicating the versions of the software and firmware that is currently installed on the patient devices (720, 730, 740). The server (710) may also transmit updated instructions (716) from over a network (4282), including a wireless network. Particular patient devices (720, 730, 740) may be selected for updating based on the configuration data (718). Upon performing an update a patient device (720, 730, 740) may transmit configuration data (728) to the server (710).

Abstract: A device and method for performing a cricothyrotomy and/or a tracheotomy has an outer cannula. An inner cutting cannula is positioned within the outer cannula. An actuator is coupled to a proximate end of the inner cutting cannula. The actuator keeps the inner cutting cannula in a retracted position within the outer cannula when the actuator is not activated and an extended position where a distal end of the inner cutting cannula extends out of the outer cannula with a force for the distal end of the inner cutting cannula to penetrate one of a cricothyroid membrane or tracheal wall when the actuator is activated.

Abstract: A patient interface device includes a cushion member, a frame member, and nasal pillows. A first side of the cushion member forms a seal with a patient's mouth. The nasal pillows are structured to form a seal with the patient's nares. The nasal pillows are attached to the frame member. The frame is attached to a second side of the cushion member. The frame member includes a connecting portion, a first aperture, and a second aperture. The nasal pillows include a first nasal pillow element and a second nasal pillow element. The first nasal pillow element is at least partially removably disposed in the first aperture. The second nasal pillow element is at least partially removably disposed in the second aperture. The connection portion is connected to the second side of the cushion member.

Abstract: Disclosed is a spring arrangement for elastically supporting a patient interface on a patient, wherein a spring body is provided, said spring body having a base structure, which is connected to the patient interface via connecting elements, wherein, starting from the base structure, inner walls and outer walls are arranged in an inclined state in relation to an axis extending in the spring direction, and wherein the walls, at least in part, form a honeycomb structure, and having a bearing surface, at least part of which extends parallel to the base structure, wherein the bearing surface is spaced apart from the base structure by at least two honeycomb structures.

Abstract: A fluid tube is disclosed herein. The breathing circuit tube has a wall which comprises a hollow geometry. The wall defines a passageway with a central longitudinal axis therethrough. The wall is expandable and contractible to adjust a diameter and a length of the passageway. The wall includes one or more corrugations that expand and contract to adjust the diameter and length of the passageway. The corrugations extend between terminal end portions of the wall.

Abstract: A method and system is provided for increasing brown adipose tissue deposits and activity by breathing air from a CPAP machine having a chiller which cools the air to less than 55° F. before discharge from the CPAP mask to the person's lungs while sleeping. The cool air increases brown adipose tissue development and activity, thereby increasing caloric expenditures, so as to lead to weight loss and other health benefits.

Abstract: The migraine treatment device of the preferred embodiments includes a threaded fitting designed to thread onto a beverage container; a valve coupled to the threaded fitting; a nozzle coupled to the valve, where the nozzle opening is smaller than the size of a human nostril; where at least some of the gas in the beverage container is one or more of: a) carbon dioxide, b) nitric oxide, c) nitrous oxide, d) an acidic gas, e) a gas that reacts with moisture to create acid, and f) an acidic vapor. The migraine treatment device is preferably designed to deliver gas into the nasal passageway of a user, where the gas is capable of reacting with moisture to create an acid so that the acid activates a sensation in the nerves of the nasal passageway, causing a reduction in a user's discomfort due to at least one of headaches and migraine headaches.

Abstract: A positive pressure airway device for providing resistance in an air pathway for a patient exhaling. The device includes a central tube region, a inspiratory air passageway for passing air into the central tube region when a patient breathing through the device inhales, and an expiratory air passageway for passing air out of the central tube region when a patient breathing through the device exhales, A valve in the expiratory air passageway allows air to flow out only when a patient using the device exhales with an expiratory air pressure greater than a selected pressure, and includes a stopper and a coil spring with an interior portion that is free from any structure that would inhibit the “side-to-side” movement of the spring within the housing. The stopper has a cone-shaped air-stopping surface providing a valve angle that is different from, and is preferably slightly less than, the valve-seat angle.

Abstract: Environmental characteristics of habitable environments (e.g., hotel or motel rooms, spas, resorts, cruise boat cabins, offices, hospitals and/or homes, apartments or residences) are controlled to eliminate, reduce or ameliorate adverse or harmful aspects and introduce, increase or enhance beneficial aspects in order to improve a “wellness” or sense of “wellbeing” provided via the environments. Control of intensity and wavelength distribution of passive and active Illumination addresses various issues, symptoms or syndromes, for instance to maintain a circadian rhythm or cycle, adjust for “jet lag” or season affective disorder, etc. Air quality and attributes are controlled. Scent(s) may be dispersed. Hypoallergenic items (e.g., bedding, linens) may be used. Water quality is controlled. Noise is reduced and sounds (e.g., masking, music, natural) may be provided. Passive and active pathogen controls are employed.

Abstract: A catheter includes: an outer tube; an inner tube provided inside of the outer tube; and a branched part that separates the outer tube and the inner tube from each other on a first end side thereof, wherein a ratio between cross-sectional areas of a first lumen formed at least by inside of the outer tube and outside of the inner tube and a second lumen formed within the inner tube is set such that a ratio between cross-sectional areas of the outer tube and the inner tube in the branched part is equal to or greater than the ratio between the cross-sectional areas of the first lumen and the second lumen in a state where the inner tube is arranged inside of the outer tube in a length direction in which the outer tube and the inner tube extend.

Abstract: A method of manufacturing a medical elongated body including an inner layer, an outer layer covering the outside of the inner layer, and a reinforcement body provided between the inner layer and the outer layer. The method includes an inner layer forming step of forming the inner layer, a reinforcement body forming step of forming the reinforcement body on an outer peripheral surface of the inner layer after the inner layer forming step, a cooling step of cooling at least a predetermined spot of the inner layer after the reinforcement body forming step, and an annealing step of annealing the reinforcement body which overlaps the predetermined spot of the inner layer cooled by the cooling step.

Abstract: Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller.

Abstract: The disclosed non-fouling, antimicrobial catheters release a therapeutically effective amount of silver ions in response to an electrical current to prevent, inhibit, or reduce bacteria or fungi from passing through the catheter into the body of a subject, for example passing through the urethra and into the bladder via the gap between the external surface of the catheter and the urethral wall. The release of silver ions in response to the electrical current also inhibits, reduces, or prevents microbes from passing through the catheter into the subject via the internal features of the catheter. The release of silver ions also reduces, inhibits or prevents microbes from colonizing and developing a fibrous matrix on the exterior surface of the catheter (also known as biofilm). Microbes on the catheter or in the tissue of a subject in contact with the catheter are killed by the ionic silver.

Abstract: A catheter stiffener adjustment system including a first member with an outer diameter and having at least three first segments with at least one joint enabling the segments to bend relative to each other, and a second member having an inner diameter defining a passageway through which the first member is movable relative to the second member. The second member has at least three second segments with at least one joint enabling the segments to bend relative to each other. In a first position, the first segments and the second segments are alignable substantially in phase to generate a first flexure condition. In a second position, the first segments and the second segments are alignable substantially out of phase to generate a second, stiffer flexure condition.

Abstract: An interventional catheter for treating an artery includes an elongated body sized and shaped to be transcervically introduced into a common carotid artery at an access location in the neck. The elongated body has an overall length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

Abstract: A deflectable medical device incorporates a strut that is configured to reduce or eliminate axial shortening of the deflectable portion of the medical device, for example, the deflectable distal end portion of a catheter or access sheath. The strut may is coaxially disposed in the medical device in the section that is contemplated to undergo the repeated deflection. The strut provides improved column strength and axial restoration. The strut may be stent-like device, an elongate device having opposing ends coupled by a connecting lattice involving a plurality of helical connecting elements or a tube having a plurality of circumferentially-extending slots arranged in longitudinally-extending rows.

Abstract: An intravenous splint cover may include a main body, a pair of opposing securing members, and a splinting member. The main body may be rectangular shaped and have a bottom portion and a top portion. The pair of opposing securing members may be rectangular shaped and be connected to and extend outwardly from the main body and have a bottom portion and a top portion. The splinting member may be rectangular shaped and be carried by the bottom portion of the main body and extend outwardly from the main body to create an elevated portion of the main body. The bottom portions of the pair of opposing securing members may have an adhesive material applied thereto. The bottom portion of the main body that does not carry the splinting member may have an adhesive material applied thereto.

Abstract: A securement device for catheter tubes and polymer coated cables includes a base mounted on a support surface, and male and female straps, the male straps having locking members that mate with corresponding apertures in the female straps. The male and female straps connect to a base via fixed ends of the respective male and female straps, and each of the fixed ends comprises a curved portion configured to orient the corresponding unsecured strap substantially parallel to the base. Each of the fixed ends of the male straps mate with a recess in the fixed ends of the corresponding female strap, thereby forming a crease for seating the tube or cable being secured.

Abstract: A protective cover for an affected area of a patient, particularly associated with an insertion site of a catheter or other puncture or opening in a patient's skin, comprising a body portion including an aperture, and a window portion, wherein the body portion and window portion each optionally comprises an antimicrobial composition. Aspects of the present invention provide articles, systems and kits for covering an incision, wound or catheter insertion site with a protective cover, and methods of using and making the protective cover.

Abstract: A needle device includes a catheter tube attached to a catheter hub, a needle attached to a needle hub, and a needle guard. The catheter hub has an interior cavity and a projection extending from an interior surface in the interior cavity. The needle projects through the catheter tube and has a needle tip extending out a distal end of the catheter tube in a ready position, a proximal end attached to a needle hub, and a shaft having a shaft diameter region, a reduced diameter region, and at least one transition region between the shaft diameter region and the reduced diameter region. The needle guard has a proximal wall and two arms extending distal the proximal wall. The two arms press against the shaft in the ready position and secure the needle tip in the protective position.

Abstract: The present application includes a sheath that is suitable for use in a variety of medical procedures. In one or more implementations, the sheath includes a shunt member, and a curvable portion. The curvable portion may be configured in various orientations to facilitate an intervention, such as a hemodialysis intervention, or the like, by an operator. The curvable portion may be configured to bend between a substantially straight configuration and a curved configuration. In implementations, the sheath may be configured to have detachable and/or interchangeable components (e.g., shunt member, curvable portion, etc.).

Abstract: A method for treating a target vascular portion of a subject including: providing an angioplasty balloon system including a balloon carrying a first therapeutic agent and a second therapeutic agent on a surface of the balloon, wherein the first therapeutic agent is an anti-proliferative or anti-mitotic agent and the second therapeutic agent is a drug that aids in vascular healing on a surface of the balloon; positioning the balloon proximate the target vascular portion; expanding the balloon to engage the target vascular portion; thereby delivering at least a portion of the active agent to the target vascular portion; and withdrawing the balloon from the subject.

Abstract: Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.

Abstract: In one embodiment of the invention a catheter (203) comprises a body having at least one inlet aperture (21, 24), at least one outlet aperture (22, 25), and at least one passage (20, 23) between the at least one inlet aperture (21, 24) and the at least one outlet aperture (22, 25). The catheter (203) is provided with pumping means (32) for selectively pumping fluid from one of said apertures (21, 22, 24, 25) to another of said apertures (21, 22, 24, 25). Methods of operating such a catheter are also disclosed.

Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter comprising an external section and a tip section, the tip section is configured to be inserted into a body of a subject; and a reconnectable indwelling stent comprising a connecting section and a target section, the target section being configured to be located within a body of the subject, wherein the connecting section of the reconnectable indwelling stent is configured to reversibly connect, within the subject body, to the tip section of the intermediary catheter to form a continuous conduit between the intermediary catheter and the reconnectable indwelling stent.

Abstract: A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site. In one embodiment, the body is made from at least one sheet of a biologically-compatible material.

Abstract: The invention pertains to apparatuses, means and methods to promote uptake of fluids into a reservoir of an implantable drug delivery system though a porous membrane. Embodiments of the invention promote fluid uptake by creating a pressure differential between the reservoir of the drug delivery device and the environment of the device after implantation, for instance a subcutaneous pocket.

Abstract: A sheath for producing a fully sealed access to the interior of a vessel of an animal or human body comprises a base sheath having a tubular body defining a pass-through channel. The base sheath is adapted to be inserted into the vessel through a vessel aperture. The sheath further comprises an expansion device which is adapted to cooperate with the base sheath such that the outer diameter of the sheath increases in the region of the vessel aperture with the sheath in a stationary position in the vessel and upon actuation of the expansion device.