Abstract: Systems and methods for analyzing genomic information can include obtaining a sequence read including genetic information; identifying, within a graph representing a reference genome, a plurality of candidate mapping positions that relate to the genetic information, the graph comprising nodes representing genetic sequences and edges connecting pairs of nodes; determining, by means of a computer system, whether an alignment with the graph surrounding each of the plurality of candidate mapping positions is advanced or basic; and performing for each candidate mapping position, by means of the computer system, a local alignment based on whether the local alignment is advanced or basic. The advanced local alignment can include a first-local-alignment algorithm, and the basic local alignment includes a second-local-alignment algorithm. Based on the local alignments, the mapped position of the sequence read can be identified within the genome.

Abstract: Disclosed herein is a system and methods for determining the alleles, neoantigens, and vaccine composition as determined on the basis of an individual's tumor mutations. Also disclosed are systems and methods for obtaining high quality sequencing data from a tumor. Further, described herein are systems and methods for identifying somatic changes in polymorphic genome data. Finally, described herein are unique cancer vaccines.

Abstract: Methods and systems for organizing, representing and processing polymeric sequence information, including biopolymeric sequence information such as DNA sequence information and related information are disclosed herein. Polymeric sequence and associated information may be represented using a plurality of data units, each of which includes one or more headers and a payload containing a representation of a segment of the polymeric sequence. Each header may include or be linked to a portion of the associated information.

Abstract: Techniques for coding a medical report include identifying an acronym or abbreviation in the medical report, and a plurality of phrases not explicitly included in the medical report that are possible expanded forms of the acronym or abbreviation in the medical report. From the plurality of phrases, a most likely expanded form of the acronym or abbreviation may be selected by applying to the medical report a statistical acronym/abbreviation expansion model trained on a corpus of medical reports. By applying to the medical report with the expanded acronym or abbreviation one or more statistical fact extraction models, a clinical fact may be extracted from the medical report based at least in part on the most likely expanded form of the acronym or abbreviation in the medical report, and a corresponding medical taxonomy code may be assigned to the extracted clinical fact from the medical report.

Abstract: In an embodiment, a computer-implemented method presents medical data. In the method, a request for medical data related to a patient is received. Then, data records in a medical records database that relate to the patient are identified. The medical records database includes a plurality of different types of medical data records, and each data record is associated with a corresponding time. According to the data records' corresponding time, the identified data records are temporally ordered to generate a timeline. Finally, the timeline is output to a device for display, such that the displayed timeline presents the plurality of different types of data records related to the patient together in a single temporal view.

Abstract: A medical data system and method of using same are provided. The medical data system includes a computing platform for using patient-specific data from each of a plurality of patients at various time points to generate a multi-dimensional vector for each of the plurality of patients at each time point of the various time points, thereby providing a plurality of time-related multi-dimensional indices for each patient. The system further uses a multi-dimensional vector generated from data at time T1 of a subject to group the subject with a first cohort of patients and a multi-dimensional vector generated from data at time T2 of the subject to group the subject with a second cohort of patients.

Abstract: An automated method is provided for recording contents of medication packages vended from a plurality of vending machines in electronic records, such as an electronic medication administration record (eMAR), that store records for a plurality of patients who are associated with respective vending machines. A vending event causes the electronic record to be populated. The contents of the medication packages vended from the vending machines are recorded in electronic records without communicating patient names or vended medications in the electronic message sent from the vending machines.

Abstract: Systems, methods, and apparatus are described for the handling of biological specimens for analysis. The systems, methods and apparatus are designed to reduce errors in misidentification, incorrect processing, and recordkeeping and reporting. The systems, methods, and apparatus can also provide real time tracking of samples at any stage, from collection to processing to analyzing to storage.

Abstract: A population health management system comprises a device that comprises a circular base with a center and an outer diameter radially distal from the center; the base includes indicia including a first criteria set located on the base in a first region; the first criteria set comprises discrete health management actionable topics spaced concentrically apart in the first region; a second criteria set is concentrically located on the base in a second region radially outward from the first region, the second criteria comprises quarterly calendar sets spaced concentrically apart as quarters in the second region; a third criteria set concentrically located on the base in a third region radially outward from the second region and proximate the outer diameter, the third criteria set comprises a plurality of symbols; a circular rotary mask is configured to conceal and reveal a portion of the indicia responsive to rotation of the rotary mask.

Abstract: A system and method for assessing gross motor functions based on user input patterns are provided. The method includes receiving raw data related to at least a movement of a user; computing, based on the raw data, at least one step feature; generating a session pattern based on the at least one step feature; and generating, using the session pattern and a decision model, a scale index indicating a current condition of the gross motor functionality of the raw data.

Abstract: An interrogation system for a medical device includes a memory storing a diagnostic algorithm, a processor configured to run the diagnostic algorithm, and a communication module configured to facilitate data transfer between the interrogation system and the medical device. The diagnostic algorithm is configured to reach a diagnostic conclusion based on data from the medical device. The diagnostic algorithm is configured to iteratively interrogate the medical device for the data from the medical device until the diagnostic algorithm reaches the diagnostic conclusion, each iterative interrogation requesting additional data as compared to prior iterations. The communication module is configured to receive the additional data from the medical device in response to each iterative interrogation. The diagnostic algorithm is further configured to store an indication of the diagnostic conclusion within the memory.

Abstract: The present invention is a method or system for acceptance testing and commissioning of a LINAC and treatment planning system (TPS). For a LINAC commissioning, the present invention collects reference data from a fully calibrated LINAC and compares the reference data with machine performance data collected from a testing LINAC. The compared results are analyzed to assess accuracy of the testing LINAC. For a TPS commissioning, the present invention collects standard reference data from standard treatment plans and standard input data and compares the standard reference data with results from standard tests that are performed by a testing treatment plan system. The compares results are analyzed to assess accuracy of the testing treatment plan system.

Abstract: A method for processing data in a data processing system, the method comprising: receiving, by the data processing system, portable device data collected by a portable device; determining, by a first data processing program of the data processing system, one or more characteristics of the portable device data; based on the one or more characteristics, selecting, by the data processing system, prompt data for transmission to a client device; and causing, by the data processing system over one or more networks, the prompt data to be transmitted to the client device.

Abstract: According to the present disclosure, a caregiver communication device includes a personal mobile device and a caregiver active workspace that includes a virtual workplace providing live access to shared data. The caregiver active workspace provides data sharing from multiple underlying architectures to accommodate caregiver and patient needs.

Abstract: An electronic device includes a memory that stores one or more medical policies and a processor. The processor is configured to obtain a request for execution of an application that provides a medical service, to decide a medical policy, which corresponds to a location of the electronic device, from among the one or more medical policies, and to selectively provide at least one function of the application based on a medical service performing method, which is determined based at least on the medical policy, from among one or more medical service performing methods.

Abstract: Method and system for providing individualized healthcare to a patient having a chronic disease over the Internet are disclosed. The system includes at least a computer server for executing application programs where the computer server includes storage means for storing patient information in at least a database server and means for communicating with at least a patient computer and a medical provider computer. The system further includes means for providing individualized web pages for interacting with the patient, means for monitoring signs and symptoms of the chronic disease using inputs provided by the patient, and means for administrating an individualized treatment of the chronic disease according to the signs and symptoms provided by the patient.

Abstract: Processes and systems for facilitating communications in a health care environment are provided. In one example, a process includes receiving a trigger from a wearable computer device to communicate with a medical application interface. The trigger may include detecting a hand gesture of a user of a wearable computer device (e.g., via a camera device or motion sensing device associated with the wearable computer device). The process may then display information associated with the medical application interface on the wearable computer device, and receive input from a user via the wearable computer device for interacting with the medical application interface. Displayed information may include patient information, medical records, test results, and so on. Further, a user may initiate and communicate with a remote user, the communication synchronizing information between two or more users (e.g.

Abstract: The present invention is a system and method for utilizing human genetic and genomic information to guide prescription dispensing and improved drug safety in a pharmacy setting. The system and method of the present invention utilizes a dedicated information management system and software to utilize patient-specific genetic information to screen for increased risk of adverse drug reactions and therapeutic responses at the time of drug dispensing.

Abstract: Described herein are methods of assessing a wide variety of physiological needs a subject (e.g., a human patient) may have as a result of an internally-driven or externally-imposed event. Aspects of the methods are computer-aided and can be used to assess a subject's need for nutritional or medicinal support. Accordingly, the invention features computer systems configured to carry out the methods described herein and computer-readable media containing program code for performing the methods. The invention also encompasses the generation of biological translation curves, and the information obtained by the present methods can be extended to include therapeutic methods that rely on complex analyses of a plurality of analytes related to a given biomarker. The invention also features pharmaceutical or physiologically acceptable compositions that are tailor-made for a given subject (e.g., a human patient) or group of subjects (e.g., a herd of livestock or crop of plants).

Abstract: The present invention relates to a method and system of risk assessment, by profiling individuals to quantify radiation or agent sensitivity and risk on both organ specific and collective whole body levels, using data including demographic information, medical records, and data from embedded, mobile or fixed sensors. The risk assessment may include analytics on genetic make-up, family history, occupational history, environmental history, medical history, physical attributes, age/gender, socio-economic status, education, and health awareness. When the data is combined with actual and estimates of radiation or agent dose exposures in a geographic environment, the net result is the creation of a risk score which determines the predicted risk an individual has for developing induced mutation, organ injury, and/or cancer.

Abstract: A safety plan application system for a convenient way for mentally handicapped patients, doctors, and caregivers to organize and store a patient's information as well as track medication usage and exercise. The application also includes contact information for critical caregivers and people who are able to make medical decisions as well as store favorite quotes, books, music, movies, and other personal preferences. The safety plan application process helps doctors view trends and analyze activity to discover when patients feel their best during their treatment program. The information is stored on an on-line service so that appropriate parties can log in and analyze data at any given time through a smart device or computer with the installed safety plan application.

Abstract: A system for a check and exception center may include a holding area, a manual section, a distribution section. The manual section may include a plurality of handling areas each enabled for pill counting, pharmacist verification, exception handling, or combinations thereof. The distribution section may be disposed proximate the manual section, and may include a robot and a scanner. The robot may be adapted to pick a container from the holding area and to move the container to the scanner for scanning. The robot may also be further adapted to direct the container to a first handling area of the plurality of handling areas.

Abstract: The present invention relates to automated devices, systems and methods for automatically controlling the dispensing of articles and for controlling access to dispensed articles, such as medication. In various aspects, an automated dispenser transfers articles from a storage compartment to an access compartment. A user has controlled access to dispensed articles in the access compartment. After a certain period of time, any untaken, dispensed articles in the access compartment can then be transferred to a holding compartment and are no longer accessible to the user. In certain aspects, an operator can access the compartments of the automated dispenser and program the automated dispenser to control the dispense and regulation of articles.

Abstract: A kiosk includes a processor configured to receive, from a user interface device, medication information and determine, via a database, that medication associated with the medication information satisfies criteria. The processor is also configured to receive, from a first camera, an image of the medication and to determine that the image of the medication satisfies a visual criterion. The processor is further configured to receive, from the scale, a weight of the medication and to determine that the weight of the medication satisfies an expected weight criterion. The processor is also configured to cause a display to display an indication that the medication satisfies the criteria based at least in part on the determination that the image of the medication satisfies the visual criterion and the determination that the weight of the medication satisfies the expected weight criterion.

Abstract: A medication administration and tracking system is described. The system is equipped with an electric medication dispenser configured to administer medication to a patient in a hospital bed without intervention from hospital staff. The dispenser is configured to allocate safe doses of prescribed or over-the-counter medications to a patient upon request by the patient. At least one method of biometric authentication is employed to solely permit access to the medication to the patient upon confirmation of his or her identity. A camera disposed on the dispenser is configured to witness the patient take the medication, and track the time and date of consumption. The medications administered are preferably equipped with a tracking sensor to help track medication levels within the patient, and monitor treatment efficacy.

Abstract: A diabetes management system including a pump for dispensing a medicant and a control device for controlling the pump includes a user interface for controlling functions of the pump and providing information related to operation of the pump and other information. The user interface can display blood glucose information and insulin dosing data such that a user can appropriately act on the information and/or gain confidence that the diabetes management system is operating appropriately to manage the disease. User interfaces provided herein can include displays of current and projected glucose values, bolus calculators, charts displaying glucose levels and/or insulin delivery data, system maintenance reminders, system status information, patient configuration input screens, and log-in screens. Diabetes management systems can include insulin pumps, continuous glucose monitors, blood glucose monitors, mobile computing devices, servers, and/or other insulin delivery devices (e.g., insulin pens).

Abstract: A medical device is disclosed. The medical device includes an RFID reader for receiving information from at least one RFID transponder. The medical device also includes a memory for storing a database and at least one processor for processing information. Also, a remote controller for a medical device is disclosed. The remote controller includes an information receiver for receiving information related to food. The infusion device also includes a memory for storing a database and at least one processor for processing information. A method for use in a medical device is also disclosed. The method includes receiving information from an RFID transponder related to food. Also, the processing the information by comparing the information to a database is included in the method. The method also includes determining the acceptability of the food and providing information related to acceptability to the user.

Abstract: A method for identifying diagnostic and therapeutic options for medical conditions. The method includes obtaining, from patient data in electronic health records, a diagnoses statistics database that includes statistical distributions of values of action results associated with diagnoses, and for each action result, a benefit of using the action result for disambiguating pairs of diagnoses. The method further includes obtaining an initial differential diagnosis for a patient. The initial differential diagnosis includes a set of initial diagnoses that are based on initially available patient data. Each initial diagnosis is assigned a probability that the initial diagnosis correctly identifies a condition of the patient.

Abstract: In a content protection scheme, and in response to a request for a content segment received by a server, the server generates and associates with the segment a message that confers entitlement to a session-specific key from which one or more decryption keys may be derived. The decryption keys are useful to decrypt the segment at runtime as it is about to be rendered by a player. Before delivery, the server encrypts the segment to generate an encrypted fragment, and it then serves the encrypted fragment (and the message) in response to the request. At the client, information in the message is used to obtain the session-specific key. Using that key, the decryption keys are derived, and those keys are then used to decrypt the received encrypted fragment. The decryption occurs at runtime. The approach protects content while in transit to and at rest in the client browser environment.

Abstract: To resolve a conflict between CMIS secondary types and certain ECM features such as content server categories, and allow the underlying ECM system to be fully CMIS-compliant, an ECM-independent ETL tool comprising a CMIS-compliant, repository-specific connector is provided. Operating on an integration services server at an integration tier between an application tier and a storage tier where the repository resides, the connector is particular configured to support CMIS secondary types and specific to the repository. On startup, the connector can import any category definition from the repository. The category definition contains properties associated with a category in the repository. When the category is attached to a document, the properties are viewable via a special category object type and a category identifier for the category. Any application can be adapted to leverage the ECM-independent ETL tool disclosed herein.

Abstract: Examples of techniques for detecting and tracking virtual containers are disclosed. In one example implementation according to aspects of the present disclosure, a computer-implemented method includes detecting a virtual container. The method further includes collecting virtual container data for the virtual container. The method also includes associating, by a processing device, the virtual container to at least one of a plurality of images. Additionally, the method includes building, by the processing device, a container event database based on the virtual container data and the association of the virtual container to the at least one of the plurality of images, so as to enable tracking of software in the plurality of images and in live virtual containers.

Abstract: Disclosed is active content. The active content includes at least content that is capable of being played by a player and content control code, which is executable in a computer, for controlling the content depending on an intention parameter, wherein the intention parameter is set in order to control at least playback or distribution of the content.

Abstract: Embodiments of the present application disclose a method and system for identifying whether an application is genuine by means of digital watermarks, which can conveniently determine whether an application is genuine.

Abstract: A watermarked content generating device including processing circuitry which performs active element conversion that converts a specified active modification target element from among elements included in an original content, based on a modification control code that is generated based on embedded information, when generating a structured content including at least a structured document, and performs passive element conversion that converts a specified passive modification target element from among elements included in the original content such that a change in a perceptual aspect of the original content corresponding to an active modification result element which results from the active element conversion is returned to having a same or equivalent perceptual aspect as that of the original content.

Abstract: A method for authenticating a user. The method includes the act of recording first data about an environment at a first time. A user interaction with the environment is stored as a stored password. Second data about the environment is received through an image sensor at a second time. While receiving the second data about the environment, a password is entered. The entered password is compared with the stored password.

Abstract: A user classification apparatus and method using a keystroke pattern based on a user posture are provided. A user classification method using a keystroke pattern may include receiving keystroke data from a user, extracting feature information corresponding to a unique pattern of the user using the received keystroke data, comparing the extracted feature information to a pattern of a keystroke profile for each posture of the user pre-generated through training, and determining whether currently input keystroke data is data of a trained user based on a result of the comparing.

Abstract: An adaptive updating method of an enrollment database is disclosed. The method may include extracting a first feature vector from an input image of a user, determining whether the input image is to be enrolled in an enrollment database based on the first feature vector, second feature vectors of enrollment images including initial enrollment images enrolled in the enrollment database, and a representative vector representing the initial enrollment images, and enrolling the input image in the enrollment database based on a result of the determining.

Abstract: This invention is directed to an electronic device with an embedded authentication system for restricting access to device resources. The authentication system may include one or more sensors operative to detect biometric information of a user. The sensors may be positioned in the device such that the sensors may detect appropriate biometric information as the user operates the device, without requiring the user to perform a step for providing the biometric information (e.g., embedding a fingerprint sensor in an input mechanism instead of providing a fingerprint sensor in a separate part of the device housing). In some embodiments, the authentication system may be operative to detect a visual or temporal pattern of inputs to authenticate a user. In response to authenticating, a user may access restricted files, applications (e.g., applications purchased by the user), or settings (e.g., application settings such as contacts or saved game profile).

Abstract: A system may identify a user based on inputs from multiple devices. The system may determine a confidence score based on the probability that the system accurately identifies the user. The system may provide a permissions level based on the confidence score. The permissions level may affect the type of interactions the user may perform with a device. The system may determine a privacy level for an interaction based on determining whether the user is in a public or private setting.

Abstract: A function performing apparatus includes a function performing unit performing a specific function, a processor, and memory storing computer-readable instructions therein, the computer-readable instructions, when executed by the processor, causing the function performing apparatus to perform, in response to receiving a user authentication information when the user authentication information has been registered in an authentication memory, transitioning a state of the apparatus from a non-permission state to a permission state, registering, in the authentication memory, a device authentication information in association with the user authentication information upon establishing a first connection with a portable device, and transitioning the state of the apparatus from the non-permission state to the permission state when a second connection with the portable device is established and the device authentication information is obtained from the portable device.

Abstract: A computer-implemented method, according to one embodiment, includes receiving a request for a hypervisor to run a virtual machine; determining, using a processor, whether the virtual machine is authorized to run using a data structure having metadata about properties of the virtual machine; determining, using the processor, whether the hypervisor is authorized to run the virtual machine using a digital signature of the data structure; and running the virtual machine on a computer system using the hypervisor in response to determining that the virtual machine is authorized to be run and that the hypervisor is authorized to run the virtual machine. Other systems, methods, and computer program products are described in additional embodiments.

Abstract: Various techniques are disclosed for managing and modifying data items. In some embodiments, a first data item can be selected for password protection via establishing an active secured user session according to a set of user credentials. Thereafter, subsequent data items can be selected for password protection using the same set of user credentials while the secured user session remains active. In some embodiments, a gesture input can be received by a touch interface. The input can be detected, and when the input is recognized as a command for creating an extension of a work space associated with a data item, then the extension of the work space is generated. In some embodiments, the gesture input received by the touch interface is recognized as a command for creating a new work space associated with the data item such that a new work space is generated upon recognizing the input.

Abstract: An apparatus for use as a single sign on entity (100) for controlling access to one or more devices (104a-d) in a computer network, the devices accessible with a device access password; the apparatus comprises a password generator configured to generate current and future device access passwords, a back-up controller configured to store a back-up comprising the current and future device access passwords at the time of the back-up in a memory, a password changer configured to change the current device password to one of the future device access passwords and to control a transmitter to transmit data implementing the change to the device, wherein the back-up controller is configured to restore the device access password from the backed-up future device access passwords, losing the current device access password.

Abstract: Method for repeatable creation of random file enables to create and recreate random files at different places, different times and on different devices. Random files are based on aliases, which can contain any text, including specific information, such as serial number, start date, expiry date, etc. Random files can be used for generations of strong and unique passwords. The strength of the password doesn't depend on alias, so any alias will result in equally strong and unique password. Browser, using the method, would be able to register the user to any resource, by generating a password, using resource's URL as alias, and afterwards automatically log user in using same URL for generating the password again. Users can communicate securely by sending alias in plaintext together with ciphertext encrypted with password. IoT devices can establish master, slave, partner, alien relationship and communicate securely without human introduction.

Abstract: A non-transitory processor-readable medium storing code representing instructions to cause a processor to perform a process includes code to cause the processor to receive a set of indications of allowed behavior associated with an application. The processor is also caused to initiate an instance of the application within a sandbox environment. The processor is further caused to receive, from a monitor module associated with the sandbox environment, a set of indications of actual behavior of the instance of the application in response to initiating the instance of the application within the sandbox environment. The processor is also caused to send an indication associated with an anomalous behavior if at least one indication from the set of indications of actual behavior does not correspond to an indication from the set of indications of allowed behavior.

Abstract: Systems, methods, computer readable media and articles of manufacture consistent with innovations herein are directed to computer virtualization, computer security and/or hypervisor fingerprinting. According to some illustrative implementations, innovations herein may utilize and/or involve a separation kernel hypervisor which may include the use of a guest operating system virtual machine protection domain, a virtualization assistance layer, and/or a CPU ID instruction handler (which may be proximate in temporal and/or spatial locality to malicious code, but isolated from it). The CPU ID instruction handler may perform processing, inter alia, to return configurable values different from the actual values for the physical hardware. The virtualization assistance layer may further contain virtual devices, which when probed by guest operating system code, return the same values as their physical counterparts.

Abstract: In one implementation, a system calculating a product risk profile includes a criticality score engine to calculate a criticality score via an aggregation of values assigned to a plurality of descriptions of a component of a product criticality. In addition, the system includes a vulnerability score engine to calculate a vulnerability score via an aggregation of a quantity of security risks found during a security assessment for the product. In addition, the system includes a product risk profile engine to calculate a product risk profile for the product via a multiplication of the criticality score and the vulnerability score.

Abstract: Systems and methods are disclosed for implementing an educational mode on a portable computing device, such as a tablet computer, that is a single-user system, used serially by multiple users. Each user can have a separate user storage that may be encrypted. The computing device boots as a system user to a login screen. A first student user enters user credentials into the login screen. The computing device can reboot the user-space processes, while leaving the kernel running, rebooting the computing device as the first student user. When the first student user logs out, data to be synchronized to, e.g., the cloud, can be synchronized for the first student user while a second student user is logged into the device.

Abstract: Systems and methods are disclosed for implementing an educational mode on a portable computing device, such as a tablet computer, that is a single-user system, used serially by multiple users. Each user can have a separate user storage that may be encrypted. The computing device boots as a system user to a login screen. A first student user enters user credentials into the login screen. The computing device can reboot the user-space processes, while leaving the kernel running, rebooting the computing device as the first student user. When the first student user logs out, data to be synchronized to, e.g., the cloud, can be synchronized for the first student user while a second student user is logged into the device.

Abstract: An system is described herein that comprises an operating system including one or more applications running on computing hardware of a smart mirror device. The one or more applications provide a boot component for controlling low level firmware and boot processes, wherein the boot component loads an initialization process. The one or more applications provide a graphical interface for launching and displaying device applications. The one or more applications provide an authorization component for authorizing installation of the device applications, wherein the authorization component comprises an installation component for installing the device applications. The one or more applications provide a communications interface for establishing communications with a mobile application running on a processor of at least one mobile device.