Patents Issued in August 17, 2017
  • Publication number: 20170232145
    Abstract: The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral matrices or scaffolds that are substantially decellularised for subsequent transplantation/implantation.
    Type: Application
    Filed: May 1, 2017
    Publication date: August 17, 2017
    Inventors: Eileen Ingham, Gemma Jones, Hazel Fermor, John Fisher, Jahid Hasan
  • Publication number: 20170232146
    Abstract: A tissue-engineered bone marrow for personalized therapy of a patient is described. The tissue-engineered bone marrow includes an autologous fibrin scaffold and a plurality of patient-derived cells isolated from the patient's bone marrow. The autologous fibrin scaffold is made using fibrinogen isolated from the patient's bone marrow. The plurality of patient-derived cells may include cells associated with a hematological or metastatic malignancy, bone marrow stromal cells, and endothelial cells. The patient-derived cells are cultured on the autologous fibrin scaffold to create the tissue-engineered bone marrow. The tissue-engineered bone marrow may be used for personalized drug screening.
    Type: Application
    Filed: May 3, 2017
    Publication date: August 17, 2017
    Inventors: Abdel Kareem Azab, Pilar de la Puente
  • Publication number: 20170232147
    Abstract: The present invention generally relates to bioactive composites of polymer and glass and, more particularly, to bioactive implants. The present invention also relates to methods of manufacturing bioactive composites. The bioactive composite finds utility in a variety of load-bearing clinical applications including spine, orthopaedic and dental procedures.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 17, 2017
    Inventors: Theodore D. Clineff, Marissa M. Conrad, Matthew B. Havener, James P. Murphy, Zachary S. Szczerbinski
  • Publication number: 20170232148
    Abstract: Systems and methods are disclosed for body augmentation by mixing hyaluronic acid (HA) with polyvinyl alcohol (PVA) to form an HA-PVA hydrogel; and exposing the HA-PVA hydrogel to one or more freeze-thaw cycles or to an amount of radiation effective to crosslink the HA to the PVA to crosslink the HA to the PVA.
    Type: Application
    Filed: January 19, 2017
    Publication date: August 17, 2017
    Applicant: MIBA MEDICAL INC.
    Inventors: Phi Nguyen, Loc Phan, Bao Tran, Thuan Nguyen, Duy Bui
  • Publication number: 20170232149
    Abstract: The invention relates to a composition for the release of an active ingredient, comprising a porous matrix, a filled carrier in the matrix and the active ingredient in the carrier. The invention is suitable for the treatment of bone cancers.
    Type: Application
    Filed: October 27, 2015
    Publication date: August 17, 2017
    Applicant: I.CERAM
    Inventors: François BERTIN, Eric DENES, Fabrice FIORENZA, Franck STURTZ, Daniel SETTON
  • Publication number: 20170232150
    Abstract: A skeletal-hole plug comprising a hardened bone cement, which has a circular or polygonal column, and the column is a porous hardened bone cement with a porosity of 30% to 90% by volume, which can be used to rapidly fill the skeletal holes resulted from the removal of bone screws, or from the removal of teeth, and to induce rapid growth of osteocytes in the skeletal holes.
    Type: Application
    Filed: November 15, 2016
    Publication date: August 17, 2017
    Inventors: Jiin-Huey Chern LIN, Chien-Ping JU, BING-CHEN YANG
  • Publication number: 20170232151
    Abstract: A solid solution for use in bone regeneration. The solid solution includes two divalent cations, wherein a first divalent cation is calcium ion (Ca2+) and a second divalent cation is selected from the group consisting of magnesium ion (Mg2+), zinc ion (Zn2+), barium ion (Ba2+) and strontium ion (Sr2+). The solid solution also includes at least one anion, and the at least one anion comprises one or more of sulfate (SO42?), phosphate (PO42?), carbonate (CO32?), and silicate (SiO32?).
    Type: Application
    Filed: February 9, 2017
    Publication date: August 17, 2017
    Inventors: WEI-HSING TUAN, PO-LIANG LAI, MAN-PING CHANG, CHIA-JUNG WU, HSIU-CHING HSU
  • Publication number: 20170232152
    Abstract: A copolymer containing polyether blocks and polyamide blocks for manufacturing an inflatable catheter element, such as a catheter balloon, with improved bursting strength, in which said copolymer has the following characteristics: number-average molecular mass of the PE blocks greater than 500 g/mol, and number-average molecular mass of the PA blocks greater than 10 000 g/mol.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 17, 2017
    Applicant: ARKEMA FRANCE
    Inventors: René-Paul EUSTACHE, Frédéric MALET, Eric GAMACHE, Alejandra REYNA-VALENCIA, Damien RAULINE
  • Publication number: 20170232153
    Abstract: Various embodiments relate to catheter locking solutions and catheter locking therapies with use of trisodium citrate and ethyl alcohol, and in particular 4.0 to 15.0 weight/volume % trisodium citrate as an anticoagulant component and/or an antibacterial component and 15.0 to 25.0 volume/volume % ethyl alcohol as an antibacterial component. Use of the catheter locking solution and catheter locking therapy can reduce treatment failure during medical procedures that may employ catheters to supply treatment by at least significantly reducing the risks associated with bloodstream infections, catheter system malfunction, emboli formation, patient discomfort, and patient illness. These benefits can be partially due to the synergistic antibacterial effects of the trisodium citrate and ethyl alcohol in solution, generating an effective catheter locking solution with minimal concentrations of ethyl alcohol.
    Type: Application
    Filed: February 6, 2017
    Publication date: August 17, 2017
    Inventors: Premkumar Babu, Benjamin R. Brozanski, Lisa Pagano, Jeffrey S. Bennett
  • Publication number: 20170232154
    Abstract: Biomaterials and methods and uses for repair or augmentation of tissues are provided. In particular, the invention provides a multi-layered, naturally occurring multi-axial oriented biomaterial comprising predominately type I collagen fibers. The invention further provides methods and uses for repair or augmentation of tissues using biomaterials of the invention.
    Type: Application
    Filed: February 28, 2017
    Publication date: August 17, 2017
    Inventors: Barry K. Bartee, Richard A. Rosen
  • Publication number: 20170232155
    Abstract: The present invention includes an apparatus and method of making the apparatus that biomedical apparatus comprises a device adapted for use in a biomedical application that comprises a high entropy alloy comprising at least 5 elements.
    Type: Application
    Filed: February 15, 2017
    Publication date: August 17, 2017
    Inventor: Aleksandra Fortier
  • Publication number: 20170232156
    Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
    Type: Application
    Filed: May 2, 2017
    Publication date: August 17, 2017
    Inventors: XIAODONG MA, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
  • Publication number: 20170232157
    Abstract: A tissue closure device can include a structural material and a stimulus responsive material on or in the structural material. The structural material can be biodegradable and/or bioabsorbable (e.g., biocompatible natural and/or semi-natural and/or synthetic polymer). The stimulus responsive material can be a particle, such as a nanoparticle. The structural material is shaped as a suture, staple, screw, patch, adhesive, sealant, or the like. A biologically active agent can be included. A method of promoting wound healing can include: approximating tissue portions; and stimulating the stimulus responsive material with a stimulus to cause the tissue portions of the wound to adhere to each other. The stimulus is selected from optical, electrical, thermal, chemical, mechanical, magnetic, acoustic, pressure, shear, biological, or enzymatic sources.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 17, 2017
    Inventors: Kaushal Rege, Taraka Sai Pavan Grandhi, Jerry Crum, Russell Urie
  • Publication number: 20170232158
    Abstract: The present invention relates to a medical device. In particular, the present invention concerns a medical device which can be detected by means of magnetic resonance imaging (MRI).
    Type: Application
    Filed: May 3, 2017
    Publication date: August 17, 2017
    Applicant: MARVIS INTERVENTIONAL GMBH
    Inventors: Klaus Düring, Joachim Georg Pfeffer
  • Publication number: 20170232159
    Abstract: The infant nasal suction apparatus is disclosed for clearing the nasal passages of small babies and toddlers. The invention provides stress-free mucus extraction and allows the child to breathe easily and freely. The nasal suction apparatus is comprised of the suction housing, which includes the motor, battery, suction level adjustment controls, and an on/off switch. A collection container is removably connected to the suction housing, and a fluid conduit is connected to the container and adapted for placement in a nostril. The infant nasal suction apparatus is arranged for the removal of excess fluid and mucus from an infant nasal passageway and is controlled by the provided speed adjustment controller.
    Type: Application
    Filed: February 16, 2016
    Publication date: August 17, 2017
    Inventor: Jessica Mackey-Jean
  • Publication number: 20170232160
    Abstract: An incising and medicating syringe is described which is configured to form raised skin areas of effected skin and lance the skin to extract subdermal fluid and distribute medical ointment. The device is employed by placement of an aperture over the effective area whereafter translation of a plunger extends a lance which subsequently withdraws to absorb and contain the excreted fluid.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 17, 2017
    Inventor: Gabriel Cardwell
  • Publication number: 20170232161
    Abstract: A method of irradiating a wound that includes positioning a wound insertion foam within a wound cavity of a wound and covering the wound insertion foam using a wound sealing layer. The method further includes pumping fluid from the wound cavity using a drain tube sealed within the wound cavity and coupled to a vacuum source, and irradiating the wound using a light diffusing optical fiber that is optically coupled to a therapeutic light source and includes light scattering structures distributed along the light diffusing optical fiber. A portion of the light diffusing optical fiber is positioned within a wound tissue region of the wound, the wound cavity, or both, such that light emitted by the therapeutic light source enters the light diffusing optical fiber, scatters outward from the light diffusing optical fiber, and irradiates the wound tissue region, a wound cavity surface of the wound, or both.
    Type: Application
    Filed: July 6, 2016
    Publication date: August 17, 2017
    Inventors: Edward John Fewkes, Stephan Lvovich Logunov, Cynthia Jean Wilson
  • Publication number: 20170232162
    Abstract: A moisture trap for removing liquid from a fluid drawn from a tissue site treated with reduced pressure and systems and methods for using the same are described. The moisture trap may include a barrier adapted to be fluidly coupled to and define an indirect fluid path between a fluid reservoir and a reduced-pressure source. The barrier may have a hydrophilic surface. The moisture trap also may include a sump adapted to receive condensation from the barrier.
    Type: Application
    Filed: April 26, 2017
    Publication date: August 17, 2017
    Inventors: Richard Daniel John COULTHARD, Christopher Brian LOCKE
  • Publication number: 20170232163
    Abstract: The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.
    Type: Application
    Filed: March 6, 2017
    Publication date: August 17, 2017
    Applicant: MACO PHARMA S.A.
    Inventors: Wolfram Hubert Walker, Frank Tolksdorf, Thierry Verpoort, Francis Goudaliez
  • Publication number: 20170232164
    Abstract: The present invention is a decompression needle assembly having a needle that is removable received into to a catheter. The catheter can include a rigid portion and a deformable portion wherein the deformable portion can be multi-ported at its distal end. A one-way valve contained in a catheter hub attached to the catheter wherein the one way valve is in an open position when the needle is received in the catheter. Lateral catheter openings can be defined in the catheter and disposed adjacent to a distal end of the catheter. A plunger can be received within the needle and have an visual and auditory indicator that can be appreciated through the needle hub.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 17, 2017
    Applicant: North American Rescue, LLC
    Inventors: Matt Cupelli, Brent Bronson, Scott Bolleter
  • Publication number: 20170232165
    Abstract: A support apparatus, which is fastened to the center and to the left and right straps of an article of clothing suitable for nursing (e.g. a nursing bra), and can be worn for extended periods of time (e.g. a full work day). The support apparatus is operable in an open and closed position. In its open position, it securely holds a breast pump's shield on a breast, enabling a woman to pump breast milk in a “hands-free” manner, while also allowing for translational motion of the breast shield. In its closed position, it lays flat against a woman's chest without obstructing access to her breasts, enabling the woman to breastfeed an infant while wearing it. By operating the two positions of the support apparatus, a woman has the option of pumping milk in a “hands-free” manner with one breast, and simultaneously breastfeeding an infant with the other breast.
    Type: Application
    Filed: February 14, 2017
    Publication date: August 17, 2017
    Inventor: Crystal B. Harris
  • Publication number: 20170232166
    Abstract: Described are systems and methods for administration of nitric oxide (NO) with use of left ventricular assists devices (LVADs), as well as systems and methods for monitoring the NO delivery devices and/or the LVAD.
    Type: Application
    Filed: January 30, 2017
    Publication date: August 17, 2017
    Applicant: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED
    Inventors: Jim Potenziano, Douglas Alan Greene, Craig Flanagan
  • Publication number: 20170232167
    Abstract: A catheter (20), which can be part of an intravascular blood pump, possesses a kink sensor which extends over the total length of the catheter and comprises an optical fiber (28A). The optical fiber is attached to an evaluation device (100) which evaluates a preset light quantity transmitted through the optical fiber as to whether a part of the light quantity is coupled out of the optical fiber along the length of the optical fiber. This is interpreted as a kink event and displayed. The optical fiber preferably utilized for the kink sensor is the optical fiber of an optical pressure sensor.
    Type: Application
    Filed: May 3, 2017
    Publication date: August 17, 2017
    Inventors: Gerd Spanier, Thorsten Siess
  • Publication number: 20170232168
    Abstract: A blood pump includes a hub having an axis of rotation and a generally cylindrical shape. The hub has an upstream end region, a central region, and a downstream end region, and the hub includes a magnetic material. Blades that are disposed on the downstream end region of the hub extend downstream of the hub.
    Type: Application
    Filed: November 22, 2016
    Publication date: August 17, 2017
    Inventors: Steven H. Reichenbach, Stephen G. Briana, William V. Hodges, Eric Lee, Yi-Ren Woo, Onur Dur, David Gary Eldridge, Pieter W.C.J le Blanc
  • Publication number: 20170232169
    Abstract: A catheter assembly can include a cannula disposed at a distal portion of the catheter assembly. The cannula can have a collapsed configuration and an expanded configuration. The cannula can be arranged to permit the flow of blood therethrough when in the expanded configuration. The catheter assembly can comprise a tip member coupled with a distal portion of the cannula. A guide feature can be configured to receive a guidewire through a guide lumen formed through the guide feature. The catheter assembly can be configured such that, when the catheter assembly is inserted into a patient with the guidewire, the guidewire passes through the guide lumen and along at least a portion of an outer surface of the catheter assembly.
    Type: Application
    Filed: August 14, 2015
    Publication date: August 17, 2017
    Inventor: Paul F. Muller
  • Publication number: 20170232170
    Abstract: Miniature axial flow pumps are implanted inside the heart or major arteries to provide hemodynamic support. These pumps commonly utilize tubular blood conduit tubes to transport blood across the aortic valve. The valve leaflets themselves are very thin and flexible, and will seal against the conduit if it is centered within the valve orifice. The present invention provides a conduit support device that retains the conduit centered within the annulus of the natural heart valve. A leaflet valve stent may be combined with a conduit support device comprised of a ring supported by posts attached to the valve stent ring. A blood pump may be attached to the center of a transvalvular support stent, for optimal fixation of the pump with relation to a trileaflet or bi-leaflet tissue or polymer valve.
    Type: Application
    Filed: May 1, 2017
    Publication date: August 17, 2017
    Inventor: Robert JARVIK
  • Publication number: 20170232171
    Abstract: The invention relates to a flexible shaft arrangement having a flexible hollow shaft (1, 2) which has an, end at the drive side and an end at the output side, wherein the hollow shaft is reinforced sectionally between these ends by a core (3, 4) extending in its interior. Stiffer and more flexible sections can hereby be selectively positioned within the shaft arrangement.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 17, 2017
    Inventors: Daniel Roehn, REINER LIEBING
  • Publication number: 20170232172
    Abstract: Described are aspects and embodiments directed to systems for tapping into the breathing system to generate pressure in a sustained space with pulsating frequency to aid the pumping functions of cardiac muscle. In some embodiments, the generated energy can also be transferred to other forms of energy (e.g., electricity to power certain devices (e.g., pacemaker batteries). In further embodiments, the system utilizes air entrapment in a closed space to generate mechanical force with valves and timed release frequency to control power generation and mechanical movements that assist blood flow.
    Type: Application
    Filed: May 1, 2017
    Publication date: August 17, 2017
    Inventor: Sameh Mesallum
  • Publication number: 20170232173
    Abstract: An airtrap for a medical or physiological fluid in one embodiment includes a conical housing having a radius that increases from its top to its bottom when the housing is positioned for operation; a medical or physiological fluid inlet located at an upper portion of the conical housing; a medical or physiological fluid outlet located at a lower portion of the conical housing, the inlet and the outlet positioned and arranged so that medical or physiological fluid spirals in an increasing arc around an inside of the conical housing downwardly from the inlet to the outlet; and a gas collection area located at an upper portion of the conical housing. In another embodiment, the airtrap is shaped like a seahorse having a head section and a tail section. Any of the airtraps herein may be used for example in blood sets, peritoneal dialysis cassette tubing, and drug delivery sets.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 17, 2017
    Inventors: Mark Perry, Jorge DelCastillo, Matthew Muller, Carlos Corrales, Atif Yardimci, James Laird
  • Publication number: 20170232174
    Abstract: The invention relates to a blood treatment device comprising an attachment unit 7 for attaching a functional unit 1 intended for single use for carrying out the blood treatment. The blood treatment device according to the invention is characterised by a monitoring unit 8 for monitoring the operability and/or the operating state of the functional unit 1, which functional unit comprises at least one light transmitter 17A, 18A and at least one light receiver 17B, 18B. The light transmitter and light receiver are arranged in the monitoring unit 8 according to the invention on one side of the functional unit 1. The arrangement of the light transmitter and light receiver on the same side has the advantage that the monitoring unit 8 can be integrated into the attachment unit 7 of the blood treatment device without any major structural modifications.
    Type: Application
    Filed: July 21, 2015
    Publication date: August 17, 2017
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Daniel Gerlach, Jurgen Hacker, Joachim Noack, Peter Scheunert
  • Publication number: 20170232175
    Abstract: A peritoneal dialysis device includes a disposable tubing set that includes a fill line with a patient access connector at one end and a dialysis fluid receiving end opposite the patient access connector end. The device also includes a fill-side pressure measuring sensor attached at the fill end and forming a disposable component of the tubing set and a patient-side pressure measuring sensor located at the fluid receiving end. The patient-side and fill-side pressure measuring sensors are adapted for measuring pressure in the fill line at the respective ends thereof. The device also includes a controller configured to regulate a rate of flow in the fill line responsively to a signal from the at least the patient-side pressure measuring sensor.
    Type: Application
    Filed: March 31, 2017
    Publication date: August 17, 2017
    Applicant: NxStage Medical, Inc.
    Inventors: Jeffrey H. BURBANK, James M. BRUGGER, Dennis M. TREU, Mark T. WYETH
  • Publication number: 20170232176
    Abstract: The present invention relates to an apparatus for determining the peritoneal pressure in the abdomen of a patient and/or for determining the drainage state of the abdomen of a patient, wherein the apparatus comprises at least one pump for conveying a dialysis solution into the abdomen as well as at least one measurement device for measuring the pressure in the dialysis solution, wherein the apparatus comprises at least one control unit that is configured such that it controls the pump and the measurement device such that a first measurement of the pressure is carried out by the measurement device with a stationary pump to obtain a first measured pressure value, the pump is subsequently put into operation to convey a partial volume of the total inflow volume of the dialysis solution into the abdomen, and the pump then stops, and then a second measurement of the pressure is carried out by the measurement device to obtain a second measured pressure value.
    Type: Application
    Filed: August 10, 2015
    Publication date: August 17, 2017
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Torsten HOCHREIN, Frank HEDMANN
  • Publication number: 20170232177
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Application
    Filed: November 2, 2016
    Publication date: August 17, 2017
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Publication number: 20170232178
    Abstract: A blood processing apparatus (1) comprises a measurement device (8) having a first chamber element (80) for measuring a haematocrit value of a blood fluid, the first chamber element (80) comprising a first inlet port (800) connectable to a first reservoir container (2) for allowing a flow from the first reservoir container (2) into the first chamber element (80) and a first outlet port (801) for allowing a flow out of the first chamber element (80), and the second chamber element (81) comprising a second inlet port (810) for allowing a flow into the second chamber element (81) and a second outlet port (811) connectable to a second reservoir container (3) for allowing a flow out of the second chamber element (81) towards the second reservoir container (3).
    Type: Application
    Filed: August 3, 2015
    Publication date: August 17, 2017
    Applicant: Fresenius Kabi Deutschland GmbH
    Inventors: Artur Meisberger, Melanie Fahrendorff, Ilka Sternheimer, Lars Michel, Frank Schmidt
  • Publication number: 20170232179
    Abstract: The invention relates to a method of purging gas bubbles from a target zone of an extracorporeal blood circuit of a dialysis machine, wherein the target zone is flowed through by flushing liquid which enters into the target zone through an inflow and exits it again through an outflow, wherein the inflow differs from the arterial port and the outflow differs from the venous port of the extracorporeal blood circuit. The invention furthermore relates to a dialysis machine having an extracorporeal blood circuit and a control unit, with the extracorporeal blood circuit having an inflow and an outflow for flushing liquid, with the inflow differing from the arterial port and the outflow differing from the venous port of the extracorporeal blood circuit, and with the control unit being configured to carry out a method in accordance with the invention.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 17, 2017
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Ralf WOJKE, Paul WIENEKE
  • Publication number: 20170232180
    Abstract: Provided is a priming method including a step of filling a priming liquid in a hollow-fiber membrane module in which hollow-fiber membranes are packed in a vessel having an inlet port, an outlet port, and a filtrate discharge port at a linear velocity of 20 cm/min or more and 550 cm/min or less through the inlet port or the outlet port in an amount of 15% or more relative to a volume of the hollow-fiber membrane module. According to the present invention, the effective filtration area at the time of cell suspension treatment is increased, and the recovery rate of cells and the filtration rate can be improved. Further, since the cell treatment can be completed while maintaining the closed environment, the obtained cells can be provided for therapeutic applications.
    Type: Application
    Filed: April 28, 2017
    Publication date: August 17, 2017
    Applicant: KANEKA CORPORATION
    Inventors: Nobuyoshi UMEDA, Shuhei TANIGUCHI
  • Publication number: 20170232181
    Abstract: Disclosed is an artificial heart and lung apparatus (100) that can be connected to a patient (P), and transfers removed blood to a human body via a roller pump (120), the system including: the roller pump (120); a blood removal line (101) which transfers removed blood to the roller pump (120); a first blood transfer line (104) that transfers blood, which is transferred from the roller pump (120), to the human body; a blood removal rate sensor (111) that is provided in the blood removal line (101); and a control unit (140), in which the control unit (140) performs control such that a blood transfer rate of the roller pump (120) is in a specific range with respect to a blood removal rate measured by a blood removal rate sensor (111).
    Type: Application
    Filed: August 20, 2015
    Publication date: August 17, 2017
    Inventors: Yoshinari NIIMI, Masahiro KAMIYA
  • Publication number: 20170232182
    Abstract: The preset invention discloses an artificial heart and lung apparatus (100) including a roller pump (120); a blood removal line (101); a first blood transfer line (104); a blood removal rate sensor (111) and a control unit (140) that performs linked control of the roller pump (120) in correspondence with a blood removal rate. The control unit (140) is capable of detecting that the blood removal rate deviates from a blood removal condition set in advance, and out-of-set condition blood removal is performed.
    Type: Application
    Filed: August 20, 2015
    Publication date: August 17, 2017
    Applicant: SENKO MEDICAL INSTRUMENT Mfg. Co., Ltd.
    Inventors: Yoshinari NIIMI, Katsunori TANAKA, Masahiro KIHARA, Munehiro KISHI, Taku MARUYA, Masanori YOSHIHARA, Masahiro KAMIYA
  • Publication number: 20170232183
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Application
    Filed: May 2, 2017
    Publication date: August 17, 2017
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Publication number: 20170232184
    Abstract: A packet for a medication delivery pen comprises a pen cap integrally connected to one, some, or all of the devices listed: an unused pen needle dispenser, sharps container for used needles, folding glucose monitor, constant glucose monitor, glucose tablets/candy, lancing device, or glucose test strip holder. The integrated pen cap is configured to replace the pen cap normally supplied with the pen and the attachments and devices featured put all items needed by a diabetic in one device. This device also gives the diabetic freedom in choosing which devices they would like to or would like not to carry with them, and in what manner so as to have the highest convenience to the diabetic.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 17, 2017
    Inventor: Hunter S. BIHN
  • Publication number: 20170232185
    Abstract: A contrast injector system includes one or more devices for reducing or eliminating risk of cross-patient contamination. In particular, the contrast injector system includes at least one of a sterilization device, vibration device, and illuminator device positioned on a component of the contrast injector system, where the sterilization device, vibration device, and/or illuminator device is in communication with a console of the contrast injector system. The sterilization device has an energy emitter positioned to emit energy to one or more components of the system. The vibration device is positioned on a component of the system so as to induce acoustic vibrations on a surface of such component. The illuminator device includes a light source positioned to illuminate a component of the system.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 17, 2017
    Inventors: Robert F. Wilson, Edward R. Miller, Kendall R. Waters
  • Publication number: 20170232186
    Abstract: The invention features an implantable cell device that includes a membrane defining and enclosing a chamber; a distance body within the chamber for reducing the diffusion distance for a biological active factor to or across the membrane; and a support scaffold within the chamber for increasing the cell support surface area per unit volume of the chamber for distributing cells.
    Type: Application
    Filed: April 30, 2017
    Publication date: August 17, 2017
    Applicant: Gloriana Therapeutics sarl
    Inventors: Lars Ulrik Wahlberg, Jens Tornøe
  • Publication number: 20170232187
    Abstract: A unified dispenser for holding, mixing, and dispensing a drug includes a housing holding a diluent reservoir, a drug reservoir, and a tubing set connecting and defining a fluid communication path therebetween. A first occlusion is at the diluent reservoir, and a second occlusion is at the drug reservoir. In a storage state of the dispenser, the first and second occlusions are entirely encased within the housing and occlude the fluid communication path. First and second pull assemblies extend outside the housing. The first and second pull assemblies are coupled to the first and second occlusions, respectively, so that removal of the first and second pull assemblies removes the first and second occlusions and joins the diluent reservoir to the drug reservoir in fluid communication through the tubing set, thereby arranging the dispenser from the storage state to a use state.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 17, 2017
    Inventors: Ralph I. McNall, III, Thomas T. Donze, Andrew M. MacDonell, Serena Joshi
  • Publication number: 20170232188
    Abstract: An infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, where the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.
    Type: Application
    Filed: November 7, 2016
    Publication date: August 17, 2017
    Inventors: Kevin L. Grant, Brian D. Tracey
  • Publication number: 20170232189
    Abstract: A flexible patch pump for controllable accurate subcutaneous delivery of one or more medicaments to a patient includes a laminated layered structure. The pump may have a rigid reservoir layer including a number of rigid reservoirs disposed in a flexible material; a flexible microfluidic layer including a compliant membrane for sealing the rigid reservoirs, a network of microfluidic channels connecting the rigid reservoirs, and a number of inlet and/or outlet valves corresponding to the rigid reservoirs; and a flexible-rigid electronic circuit layer including a number of individually-addressable actuators. In operation, the rigid reservoirs may contain medicament that is dispensed in precise volumes at appropriate times due, for to example, to a pressure change in an addressed reservoir caused by displacement of the compliant membrane or other actuation element.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 17, 2017
    Inventors: Yanzhe Qin, Zhifei Ge
  • Publication number: 20170232190
    Abstract: A injection device includes: a hub; two wings extending from the hub and functioning as flashing indicators; a tube connected to a first end of the hub; a needle being in fluid communication with the second end of the hub; and a check valve is provided within the tube, wherein a fluid can flow from the tube to the hub through the check valve, and the fluid is prohibited from flowing from the hub to the tube by the check valve. The flashing indicators can be observed by a user to make sure that the needle has been properly inserted into a vein.
    Type: Application
    Filed: September 28, 2015
    Publication date: August 17, 2017
    Inventor: Farhad BYBORDI
  • Publication number: 20170232191
    Abstract: Ambulatory infusion pumps, medicament reservoirs, and medicament sealing assemblies, including a variety of trocar seal assemblies and fill plug seal assemblies, plus related components, as well as component combinations and related methods.
    Type: Application
    Filed: February 12, 2017
    Publication date: August 17, 2017
    Inventors: Roger E. Smith, Tom Xiaobai He
  • Publication number: 20170232192
    Abstract: A drug solution administration apparatus includes an injection unit comprising an injection member configured to inject a drug solution; a delivery unit configured to be coupled to and decoupled from the injection unit, the delivery unit comprising: a delivery member configured to deliver the drug solution to the injection member, and a delivery device configured to deliver the drug solution to the delivery member; a detection unit configured to detect whether the injection unit and the delivery unit are coupled or decoupled; and a control unit configured to control operation of the delivery device. The control unit is configured to perform at least one of (i) restricting the filling operation when the detection unit detects that the injection unit and the delivery unit are coupled, or (ii) restricting the administration operation when the detection unit detects that the injection unit and the delivery unit are decoupled.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 17, 2017
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Shohei SASAKI
  • Publication number: 20170232193
    Abstract: A diagnostic transceiver assembly includes a diagnostic unit that may be implanted into a human body. The diagnostic unit monitors physiological functions of the human body to include heart rate and blood serum levels. The diagnostic unit generates a diagnostic sequence when the diagnostic unit detects blood serum levels outside of a trigger ratio. A dispensing unit may be implanted into the human body. The dispensing unit is in fluid communication with the human circulatory system. The dispensing unit contains insulin. The dispensing unit releases a measured amount of the insulin into the human circulatory system in response to the diagnostic sequence.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 17, 2017
    Inventor: Paul Gargano
  • Publication number: 20170232194
    Abstract: An anesthesiology pump for automatic delivery and control of anesthetics to a patient provides a remote unit that may be carried by an anesthesiologist to improve supervision of the anesthesiology process without unnecessarily constraining the anesthesiologist's movement. The anesthesiology pump may assess one or both of a status of the anesthesiology procedure and the availability of the anesthesiologist to provide tailored alerts to the anesthesiologist when additional attention or availability may be needed. Availability may consider separation distance between the pump and the radiologist as well as express indications of availability. A set of predefined safe states permit a pump response when the anesthesiologist is not available and additional attention is required.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 17, 2017
    Inventors: Chao Young Lee, Mei Zhang