Abstract: A cohesive bone composition is made from a moldable bone composition intermixed with a bone gel composition. The cohesive bone composition is made from human cadaver bone. A fluid can be added, the fluid may also be laden with cells.

Abstract: A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substrate for engineering periosteal grafts.

Abstract: A prosthesis including a magnetic implant approximating the size of a bone to be replaced; a first magnetic bone implant securable to a first bone adjacent the bone to be replaced; and a second magnetic bone implant securable to a second bone adjacent the bone to be replaced. Each of the first and second magnetic bone implants have a magnetic relationship with the magnetic implant. A method of reconstructing a wrist includes removing a patient's scaphoid to create a void. The scaphoid has a plurality of adjacent bones, each of the adjacent bones comprising a surface generally facing the void. The surface of at least two of the adjacent bones is prepared by affixing a magnetic element thereto and a magnetic scaphoid implant is inserted into the void. A magnetic relationship exists between the magnetic elements and the magnetic scaphoid implant.

Abstract: An example implant device includes a base having a surface that mates with bone, and a plurality of tapered protrusions positioned on the base and extending from the surface of the base that mates with bone. A surface of the plurality of tapered protrusions includes a textured surface to increase area for bone growth. An example method for inserting the implant device into bone includes forcing the plurality of tapered protrusions of the implant device into the bone, and securing the implant device in place without cement due to the plurality of tapered protrusions cutting into the bone for fixation of the implant device.

Abstract: A medical device for implantation in a hip joint of a patient; the hip joint having a caput femur integrated with a collum femur having a collum and caput center axis, extending longitudinal along the collum and caput femur, in the center thereof. The medical device comprises an elongated portion adapted to at least partially replace the collum femur, wherein said elongated portion is adapted to be at least one of integrated in and connected to a prosthetic spherical portion adapted to replace the caput femur, and wherein said prosthetic spherical portion in turn is adapted to be movably placed in a prosthetic replacement for the acetabulum having at least one extending portion for clasping said prosthetic spherical portion. Said elongated portion comprises a restricting portion adapted to restrict the motion range of the spherical portion in relation to said prosthetic replacement for the acetabulum.

Abstract: The present invention regards an elbow spacer device, including: at least one ulnar section, including a stem portion extending along a substantially longitudinal axis (x-x) between a proximal end and a distal end; at least one humeral section, including a stem portion extending along a substantially longitudinal axis (y-y) between a proximal end and a distal end, the distal end of the humeral section delimiting an engagement seat with the proximal end of the ulnar section; articulation means between the distal end of the humeral section and the proximal end of the ulnar section, positionable along an axis (z-z) that is orthogonal to the substantially longitudinal axis (y-y) of the humeral section. The proximal end of the ulnar section is engageable in the housing seat.

Abstract: A spacer device for the knee joint including a femoral component, a tibial component and an intermediate component, wherein the femoral component is adapted to be constrained to an end of the femoral bone in proximity to the knee joint, wherein the tibial component is adapted to be constrained to an end of the tibial bone in proximity to the knee joint, the femoral component being adapted to come into contact and to articulate with the tibial component, wherein the intermediate component is placed in use between the femoral component and the tibial component and wherein the constrained spacer device includes a first hinge and a second hinge adapted to rotatably constrain the femoral component to the tibial component.

Abstract: This disclosure is directed to restoring joints by deploying a resilient interpositional arthroplasty implant. Such implants function to pad cartilage defects, cushion, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function. The implant may endure variable joint compressive and shear forces and cyclic loads. The implant may repair, reconstruct, and regenerate joint anatomy, and thereby improve upon joint replacement alternatives. The walls of this invention may capture, distribute and hold living cells until aggregation and hyaline cartilage regrowth occurs. The implant may be deployed into debrided joint spaces, molding and conforming to surrounding structures with sufficient stability so as to enable immediate limb use after outpatient surgery. Appendages of the implant may repair or reconstruct tendons or ligaments, and menisci by interpositional inflatable or compliant polymer arthroplasties that promote anatomic joint motion.

Abstract: An implant device having a non-conductive base structure with at least two exposed or exterior surfaces wherein at least one of the exposed or exterior surfaces has attained electrical conductivity on at least portions of the surface by an energy exposure wherein portions of the exposed or exterior surfaces are transformed by the energy exposure to attain the electrical conductivity.

Abstract: An adjustable implant includes a telescopic body with first and second portions in sliding engagement, and a deflectable linkage formed from a first linking segment, an intermediate segment and a second linking segment pivotally interconnected so that adjustment of a length of the telescopic body causes a corresponding deflection of the deflectable linkage. The first linking segment and the second linking segment are formed with projecting features that provide a partial gear engagement between the first and second linking segments such that, during adjustment of a length of the telescopic body and corresponding deflection of the deflectable linkage, pivotal motion of the first and second linking segments relative to the intermediate segment about the first and second pivot axes occurs in a fixed ratio defined by the partial gear engagement.

Abstract: The invention relates to medical implants, including spinal implants and bone grafts, for fixation and integration with hard tissue. The bone medical implants include at least one rotational fixation mechanism that further includes or is attached to one or more sharp protrusions configured to penetrate and become lodged into hard tissue to provide support and positional stability. Such support is useful to ensure that the spinal bone graft may be used without additional stabilizing or anchoring structures, such as supporting plates or screws.

Abstract: An intervertebral fusion implant for fusion of adjacent vertebrae, includes a main body having a first leg, a second leg, and an intermediate articulated joint, a pivoting blade is rotatably attached to the first leg, a guiding trough that includes two lateral side walls and two end-faces, one being stationary and one being movable and formed by a traveller movable along the guiding trough to vary its distance to the stationary end-face, the traveller being rotatably attached to the other end of the pivoting blade, wherein an attachment device is provided at the stationary end-face, and a second attachment device is provided at the traveller, which includes an aperture for passage of the holding instrument, wherein a lifting mechanism includes a lifting plate adjustable between retracted and raised states, the lifting plate being spaced from a top surface of the legs and forming a bearing for an adjacent vertebrae end-plate.

Abstract: Techniques and systems for distracting a spinal disc space and supporting adjacent vertebrae are provided. Trial instruments are insertable into the disc space to determine a desired disc space height and to select a corresponding implant. Implants can be also be self-distracting and the implant providing the desired disc space height can be implanted in the spinal disc space.

Abstract: Medical devices suitable for implantation in spaces between bones are described. An example medical device suitable for use as an intervertebral spacer includes a main body having an exterior proximal wall, an exterior distal wall, a first exterior lateral wall, a second exterior lateral wall, an upper surface, a lower surface, an interior proximal wall, an interior distal wall, a first interior lateral wall, a second interior lateral wall, and a longitudinal axis. The interior proximal wall, the interior distal wall, the first interior lateral wall, and the second interior lateral wall cooperatively define an interior cavity. The first and second exterior lateral walls are outwardly directed at an angle from the lower surface to the upper surface relative to the longitudinal axis.

Abstract: A stand-alone interbody fixation system having a cage, anterior fixation blade and posterior fixation blade. The cage includes an annular side wall with an open interior and upper and lower surfaces, the cage being configured to fit between end plates of adjacent vertebrae. The anterior fixation blade includes an anterior alignment boss with two opposing outward extending anterior blades with end plate penetrating tips configured to fit within the open interior of the cage. The posterior fixation blade includes a posterior alignment boss with two opposing outward extending posterior blades with end plate penetrating tips configured to fit within the open interior of the cage. The anterior alignment boss and posterior alignment boss being rotatably coupled to each other and with a first opening and a second opening in the annular side wall opposite the first opening.

Abstract: Disclosed are a fusion cage for a spinal surgery and a clamping device thereof. The fusion cage comprises a fusion cage body (1) and a triangular screw plate (2). A limiting groove (12) fit with the clamping device is provided at a rear end surface of the fusion cage body (1), the fusion cage body (1) is hinged with the screw plate (2), and each of three corners of the screw plate (2) is provided with a screw hole (23). The clamping device comprises two clamping rods (4) which are fit with each other, and a front end of each clamping rod (4) is provided with a clamping head (41), wherein each of face-to-face sides of the clamping heads (41) is provided with a limiting protrusion (42), a front end of each clamping head (41) is capable of being inserted into the limiting groove (12) of the fusion cage body (1), and the limiting protrusion (42) is capable of being clamped at a front side surface of the screw plate (2).

Abstract: An interbody spacer for a spine includes a housing having a plurality of clearance holes configured to engage bone of the spine. A contact plate including a plurality of apertures is positioned a distance away from the housing configured to engage bone of the spine. A plurality of rivets adjoin the housing and the contact plate. A plurality of springs are included with each spring configured to encircle a respective rivet and translate the distance between the housing and contact plate from a minimum distance to a maximum distance.

Abstract: Systems, methods and devices for providing orthopedic implant augments are provided which have fastener locking mechanisms. The augments include a surface for mating with an implant component and a surface for interfacing with a patient's bone. The fastener locking mechanisms are aligned such that the augment may be locked in a variety of orientations while maintaining close contact with both an implant and a patient's bone. The alignment of the locking mechanisms provides variability and adjustability to the augment to address a variety of bone anatomies and requirements.

Abstract: A method and system for measuring tension, pressure, and distance of knee tissue, the system comprising a prosthetic inlay device comprising at least two platform structures, wherein each of the platforms are supported on a scissor arm structure and a coil spring, a force sensing sensor configured beneath each coil spring, and a connector cable coupled to the force sensing sensors.

Abstract: In some aspects, graft devices for a mammalian patient can include a tubular member comprising a first end; and a fiber matrix surrounding the tubular member, wherein the fiber matrix is designed and constructed to be substantially continuously tapered at the first end to define a diameter that increases as it approaches the first end.

Abstract: A lumen stent preform is provided using a plasma nitriding technology, a preparation method thereof, a method for preparing a lumen stent by using the preform, and a lumen stent obtained according to the method. The preform is manufactured by using pure iron or an iron alloy containing no strong nitrogen compound, has a hardness of 160-250HV0.05/10, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. Alternatively, the preform is an iron alloy containing a strong nitrogen compound, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. The lumen stent preform meets the requirements of a conventional stent for radial strength and plasticity, so that plasma nitriding is applicable to commercial preparation of a lumen stent.

Abstract: A biodegradable in vivo supporting device is disclosed. In one embodiment, a coated stent device includes a biodegradable metal alloy scaffold made from a magnesium alloy, iron alloy, zinc alloy, or combination thereof, and the metal scaffold comprises a plurality of metal struts. The metal struts are at least partially covered with a biodegradable polymer coating. A method for making and a method for using a biodegradable in vivo supporting device are also disclosed.

Abstract: A device for placement in the aortic arch of a patient is provided. The device includes a distal portion for being engageably received in an aortic arch of a patient beyond the left subclavian artery and a stent portion fluidly engaged with the distal portion, the stent portion being permeable and configured to span a portion of the aortic arches to which the brachiocephalic trunk, left common carotid artery, and left subclavian artery attach to the aortic arch. A diameter of the stent portion may be modified by translation of the proximal portion to thereby alter a length of the stent portion thus causing modification of the diameter of the stent portion to fit anatomical features of differing dimensions.

Abstract: A stent including a plurality of curved sections and a connector. The curved sections surround a longitudinal axis to define a tube portion and are distributed along the longitudinal axis to form a helix. The connector includes a bioresorbable material and is positioned between two adjacent curved sections. The stent has a spring constant that changes to a different spring constant after exposure to biological material.

Abstract: A stent including a plurality of curved sections and a connector. The curved sections surround a longitudinal axis to define a tube portion and are distributed along the longitudinal axis to form a helix. The connector includes a bioresorbable material and is positioned between two adjacent curved sections. The stent has a spring constant that changes to a different spring constant after exposure to biological material.

Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.

Abstract: Medical systems and related methods are disclosed. In some embodiments, the medical systems include an inner tubular member defining an aperture and an outer tubular member at least partially surrounding the inner tubular member. The inner and outer tubular members can be arranged such that an implantable medical endoprosthesis can be disposed therebetween.

Abstract: A handle assembly for a delivery device the sequential release of trigger wires from a prosthesis to release the prosthesis from the delivery device. The handle assembly has two handles, one of which is a rotating handle. The rotating handle has a first and second trigger wire release mechanisms which operate to sequentially release a first and second trigger wire, respectively, and a locking mechanism. The other handle has a locking mechanism that prevents that operation of the second trigger wire release mechanism until the first trigger wire has been released.

Abstract: A system for delivering an implantable medical device to a treatment site within a patient includes an implantable medical device including a rigid body, and a delivery device. The delivery device includes an elongated catheter shaft and an expandable balloon connected to the elongated catheter shaft adjacent a distal end of the elongated catheter shaft, where the expandable balloon includes a proximal region, a distal region, and an implant retaining portion disposed between the proximal region and the distal region. The delivery device also includes a compression element connected to the implant retaining portion of the expandable balloon, where the compression element is adapted to limit expansion of the implant retaining portion of the expandable balloon when the expandable balloon is at least partially inflated. At least a portion of the compression element and the implant retaining portion are disposed within a lumen of the implantable medical device.

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath is removed by a health professional either by removing the sheath directly or using a tube containing the catheter.

Abstract: A intragastric device that contains a compressible free-floating structure and a sleeve attached thereto is provided. The device is considered to be anchorless as the sleeve is not physically attached to any portion of the GI tract. The device is configurable between a compressed pre-deployment configuration and an expanded post-deployment configuration. The free-floating device may be composed of a shape memory material such a nitinol. In some embodiments, the free-floating structure is space occupying and non-porous. The sleeve may be attached to the free-floating structure, such as with sutures and/or glue. In some embodiments, a stent may be inserted at the proximal end of the sleeve. A second free-floating structure may be connected to the free-floating structure such that there is an upper structure and a lower structure. In some embodiments, the gastrointestinal device is used to deliver prebiotic and/or probiotic therapy to a patient.

Abstract: The invention relates to a transpyloric device for accepting chyme from the stomach and conducting said chyme on in a bypass-like manner through a patient's duodenum; said device is held in place by balloon segments which sit on a preferably radially collapsible and self-erecting transpyloric conducting element; the filling level of the balloon segments, and thus the axial sealing force acting primarily on the shoulder surfaces of the pylorus or the surrounding area thereof, can be adjusted by the user, and the force applied to the stomach and duodenum structures adjoining the pylorus is reduced to a level that is permanently bearable for the organs even when the filling pressure of the segments rolling against each other is elevated. The invention also relates to an applicator for putting a bypass device of said type in place in the region of the transition from the stomach to the duodenum.

Abstract: A restraint anchor in accordance with at least one of the present inventions includes an attachment member that is adapted to be secured to a patient restraint and a base member, associated with the attachment member, that is adapted to be secured to a portion of a patient support apparatus.

Abstract: Embodiments disclosed herein are directed to drainage bag systems configured to facilitate disposal of a fluid therein and methods of using the drainage bag systems. For example, the drainage bag systems may include a drainage container configured to receive and hold a fluid from a patient. The drainage container may be fluidly coupled and reversibly attached to a bag. The bag may be configured to selectively receive at least some of fluid held by the drainage container. The bag may be detached from the drainage container and disposed of in a substantially fluid tight manner without disrupting operation of the drainage container (e.g., receiving and holding a fluid).

Abstract: An ostomy appliance comprises a pouch having first and second walls, with an inlet aperture in the first wall. A stoma seal is carried by the second wall, and is disposed generally in register with the inlet aperture for sealing against a stoma in use. An outer coupling element is coupled to the first wall and surrounds the inlet aperture. An inner coupling element for supporting the stoma seal, is coupled to the second wall and/or to the stoma seal. The outer coupling element surrounds a periphery of the inner coupling element. The stoma seal may be of an inflatable type or an insertable type. Manipulation tabs may be provided associated with the inner and outer coupling elements.

Abstract: The invention is an external urinary incontinence treatment method and device for women that assists women or a care giver in locating the orifice of the urethral tract for the connection of a tube for removal of urine. The method and device facilitate a stable and reversibly fixated connection of a urine receiving component with the skin surrounding the orifice of the urethral tract of a treated patient while minimizing the discomfort of the treatment. The device for the treatment in women of urinary incontinence comprises a urine collecting component and a stabilizing component that are reversibly connected in a manner that the distance between the components can easily be altered so as to minimize the discomfort caused to a treated patient.

Abstract: A sleep apnea treatment/anti-snoring device optionally having controlled positive air-flow using a micro-blower to maintain an individual's upper airway unobstructed (pharynx area). Optionally the device includes a lower jaw mandibular advancement component. The device has built-in sensors, microprocessor and other items required for data acquisition and transfer.

Abstract: The invention relates to devices and methods for monitoring, diagnosing and/or treating sleep apnea. Devices of the invention comprise a mouthpiece having a filter assembly and a microchip. Devices of the invention may also comprise a nasal splint having a filter assembly and a microchip. The invention also relates to a system comprising devices of the invention.

Abstract: The cooling system (100, 300, 400, 500, 700, 750) includes an applicator (101, 501, 701) configured to hold a predetermined amount of solid coolant and fluid coolant (117) to cool a targeted area of the body (162, 570) to crystalize the lipid-rich cells underneath the targeted area to reduce the fat cells. The applicator may include a thermoelectric cooler (TEC, 136, 704, 706) where the hot side is cooled by coolant held within the applicator. The cold side of the TEC may be thermally coupled to a cooling plate (138, 560) configured to cool a targeted area of the skin at a predetermined temperature range for a predetermined period of time. The cooling system may also be used to relieve localized pain at certain area of the body and/or utilized for cryotherapy.

Abstract: The present invention relates to a system (100) for controlling a temperature, the system (100) comprising: a temperature sensor module (10), which is configured to measure a temperature value; a microcontroller module (20), which is coupled to the temperature sensor module (10) and which is configured to generate AC heating pulse signals by separate sequential code steps based on the measured temperature value; a coupling module (30) which is coupled to the microcontroller module (20) and which is configured to transform the generated AC heating pulse signals into transformed AC heating pulse signals using a transfer function which is substantially zero for DC signal components; and a heating module (40) which is coupled to the coupling module (30) and which is configured to generate heat according to the transformed AC heating pulse signals.

Abstract: A method of providing moisture therapy to a subject by applying a moist therapy compress against a treated body portion. The moist therapy compress includes a fluid-permeable shell, a flexible backing fastened to the shell to define an enclosure, and a hydrophilic zeolite fill granules loosely contained within the enclosure. The therapy compress is exposed to a source of moisture to cause absorption of water into the hydrophilic zeolite, and the moisture is delivered from the hydrophilic zeolite through the fluid permeable shell to the treated body portion.

Abstract: The present invention relates to a hyperthermia mask used in the field of medical appliances. The hyperthermia mask of the present invention comprises a mask surface body and a tensioning belt, the mask surface body is made of phase change fibers or the mask surface body is filled with the phase change fibers; the phase change fibers are composed of hollow fibers and phase change materials filled into the hollow fibers; and the phase change materials have a phase change temperature of 40° C.-55° C. The hyperthermia mask of the present invention is prepared based on phase change heat storage, is convenient to use and has a good hyperthermia effect.

Abstract: An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.

Abstract: Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space of the eye. The implant can drain fluid from an anterior chamber of the eye to a physiologic outflow path of the eye, such as, the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space. Alternatively, or in addition, the implant can elute a drug or therapeutic agent. The delivery or inserter devices or systems can be used in conjunction with other ocular surgery, for example, but not limited to, cataract surgery through a preformed corneal incision, or independently with the inserter configured to make a corneal incision.

Abstract: An exemplary surgical device includes an element positionable within a shaft having a lumen defined therethrough with the element movable from a stored position to a deployed position in which a larger portion of the element extends out of the distal end of the lumen. The element forming a closed loop which is positioned around the lens while the lens is within a capsular bag. The closed loop is reduced in size to form a cut in the lens.

Abstract: A ring that can maintain a pupil in an extended position d˜ring an ophthalmic procedure. The ring has a plurality of loops that capture iris tissue. The ring is configured to extend the pupil when iris tissue is inserted into each loop. An ophthalmic procedure such as phacoemulsification can then be performed on the patient. The ring has a center opening that provides a wide view of the ocular chamber during the procedure.

Abstract: A ring that can maintain a pupil in an extended position d-ring an ophthalmic procedure. The ring has a plurality of loops that capture iris tissue. The ring is configured to extend the pupil when iris tissue is inserted into each loop. An ophthalmic procedure such as phacoemulsification can then be performed on the patient. The ring has a center opening that provides a wide view of the ocular chamber during the procedure.

Abstract: A surgical needle assembly for attachment to an ultrasonic handpiece includes an elongated metal cannula having a distal end and a proximal end. A hub is insert molded onto the cannula generally towards the cannula proximal end and formed from a material having an ultimate strength at least twice a peak cyclical stress force at a joint between the elongated metal cannula and the hub when the surgical needle assembly is in use with the ultrasonic handpiece. The hub material has a stiffness sufficient to limit a motion of the elongated metal cannula to less than 1.5 times an expected peak to peak stroke length when the surgical needle assembly is in use with the ultrasonic handpiece. The hub includes structure for mating attachment to the ultrasonic handpiece.

Abstract: A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include applying energy during at least one pulsed energy on period, typically sufficient or intended to rapidly induce and beneficially employ transient cavitation. Applying energy during the pulsed energy on period comprises applying energy during a first high energy period, and applying energy during a second nonzero lower energy period.

Abstract: Ocular surgery may be performed by a variety of systems, processes, and techniques. In certain implementations, a system and a process for ocular surgery may include the ability to draw ocular fluid into a channel of a hand-held pump system and separate the fluid into multiple compressible channels to create multiple flows. The system and the process may also include the ability to peristaltically pump the fluid through the compressible channels.